Achaogen, Inc. Patent applications |
Patent application number | Title | Published |
20150203444 | POLYMORPHS OF N-((S)-3-AMINO-1-(HYDROXYAMINO)-3-METHYL-1-OXOBUTAN-2-YL)-4-(((1R,2R)-2-(- HYDROXYMETHYL)CYCLOPROPYL)BUTA-1,3-DIYNYL)BENZAMIDE - Polymorphs of N—((S)-3-amino-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl)-4-(((1R,2R)-2-(hydroxymethyl)cyclopropyl)buta-1,3-diynyl)benzamide (Compound I) are provided. Processes for making the same, as well as related compositions and methods, are also disclosed, particularly with regard to the treatment of bacterial infections. | 07-23-2015 |
20150018331 | ANTIBACTERIAL AGENTS - Antibacterial compounds of formula (I) are provided: | 01-15-2015 |
20130217642 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 08-22-2013 |
20130178438 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 07-11-2013 |
20120283209 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 11-08-2012 |
20120283208 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 11-08-2012 |
20120283207 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 11-08-2012 |
20120283175 | ANTIBACTERIAL COMPOSITIONS - The present invention provides a methods and pharmaceutical compositions useful for treating bacterial infections in humans and animals which comprises administering to a human or animal in need thereof, a synergistic combination of an inhibitor of LpxC and second antibacterial agent. | 11-08-2012 |
20120258925 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 10-11-2012 |
20120214759 | TREATMENT OF KLEBSIELLA PNEUMONIAE INFECTIONS WITH ANTIBACTERIAL AMINOGLYCOSIDE COMPOUNDS - A method for treating a | 08-23-2012 |
20120208781 | AMINOGLYCOSIDE DOSING REGIMENS - The present invention provides new aminoglycoside dosing regimens associated with enhanced microbicidal activity and reduced nephrotoxicity, as well as methods of using these dosing regimens to treat various bacterial infections. | 08-16-2012 |
20120196791 | COMBINATION THERAPIES USING ANTIBACTERIAL AMINOGLYCOSIDE COMPOUNDS - Methods for treating a bacterial infection in a mammal in need thereof, and compositions related thereto, are disclosed, the methods comprising administering to the mammal an effective amount of an antibacterial aminoglycoside compound and a second antibacterial agent. | 08-02-2012 |
20120184501 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 07-19-2012 |
20120172332 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 07-05-2012 |
20120165282 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) or (II): | 06-28-2012 |
20120135948 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I) or (II): | 05-31-2012 |
20120135946 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 05-31-2012 |
20120135945 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 05-31-2012 |
20120122809 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 05-17-2012 |
20120058989 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 03-08-2012 |
20110288041 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 11-24-2011 |
20110275586 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 11-10-2011 |
20110224186 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS - Carbacephem β-lactam antibiotics having the following chemical structure (I) are disclosed: | 09-15-2011 |
20100267686 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS - Carbacephem β-lactam antibiotics having the following chemical structures (I) and (II) are disclosed: | 10-21-2010 |
20100190766 | ANTIBACTERIAL AGENTS - Antibacterial compounds of formula (I) are provided: | 07-29-2010 |
20100099661 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS - Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): | 04-22-2010 |
20090220982 | COMPOSITIONS AND METHODS FOR DETERMINING NEPHROTOXICITY - The present invention provides novel in vitro assays for determining the nephrotoxicity of a compound. These assays correlate well with in vivo nephrotoxicity and also provide high-throughput methods to screen multiple compounds for in vivo nephrotoxicity. In addition, the methods of the present invention may be adapted to screen for nephroprotectant compounds, including those that protect cells and animals from the nephrotoxic effects of aminoglycoside antibiotics. | 09-03-2009 |
20090136518 | Compositions and methods to reduce mutagenesis - The present invention provides methods and compositions for said inhibition of drug resistance. In one embodiment, said invention provides methods and compositions for said inhibition of antibiotic resistance. The invention generally involves said administration of achaogens, agents that inhibit said mutational process, to inhibit said evolution of drug resistance. Also, described herein are compositions that are suitable for use as achaogens. | 05-28-2009 |
20080300199 | ANTIBACTERIAL 1,4,5-SUBSTITUTED AMINOGLYCOSIDE ANALOGS - The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection. | 12-04-2008 |