Active Biotech, AB Patent applications |
Patent application number | Title | Published |
20140112946 | DEUTERIUM-ENRICHED 4-HYDROXY-5-METHOXY-N,1-DIMETHYL-2-OXO-N-[(4-TRIFLUORO-METHYL)PHENYL]-1,2- -DIHYDROQUINOLINE-3-CARBOXAMIDE - Deuterium-enriched 4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)-phenyl]-1,2-dihydroquinoline-3-carboxamide, having a deuterium enrichment in the amide-N methyl group of at least 70%; or a salt thereof with a pharmaceutically acceptable organic or inorganic cation; and a method of preparing said compounds. The compounds are useful in therapy, e.g. for the treatment of a malignant hyperproliferative disorder or an autoimmune disease. | 04-24-2014 |
20130123301 | CRYSTALLINE SALTS OF QUINOLINE COMPOUNDS AND METHODS FOR PREPARING THEM - A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II) | 05-16-2013 |
20130109860 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | 05-02-2013 |
20100166775 | S100A9 INTERACTION SCREENING METHOD - A method of identifying a compound for use in therapy which modulates the interaction of S1OO A9 with a ligand comprising: -determining whether a candidate compound is capable of modulating the interaction of S1OO A9 with RAGE or the interaction of S1OO A9 with a TLR (Toll like receptor), or -determining whether a candidate compound is capable of binding to S100A9 in a manner which disrupts binding of S1OO A9 with RAGE or the binding of S100A9 with a TLR, to thereby identify whether the compound may be used in therapy. | 07-01-2010 |
20100111978 | CONJUGATES BETWEEN A VARIANT STAPHYLOCOCCAL ENTEROTOXIN E SUPERANTIGEN AND A TARGETING ANTIBODY THAT BINDS TO A CANCER-ASSOCIATED CELL SURFACE STRUCTURE - The present invention relates to compositions and methods of use, wherein the composition comprises a conjugate of a bacterial superantigen and an antibody moiety. More particularly, the bacterial superantigen has been modified to decrease seroreactivity with retained superantigen activity. | 05-06-2010 |
20090232889 | CRYSTALLINE SALTS OF QUINOLINE COMPOUNDS AND METHODS FOR PREPARING THEM - A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II) | 09-17-2009 |