BIOSERENTACH CO., LTD. Patent applications |
Patent application number | Title | Published |
20110192562 | STAMPER FOR MICRONEEDLE SHEET, PRODUCTION METHOD THEREOF, AND MICRONEEDLE PRODUCTION METHOD USING STAMPER - Microneedle sheets are produced by injecting a needle raw material into a stamper formed with a concavity in a base material. However, because the stamper concavity is very small, there is the problem that air cannot escape due to air and surface tension of the material, thereby preventing a needle from being formed in part. The present invention provides a stamper for producing a microneedle sheet. The stamper comprises a sheet-like base material including a conical concavity formed from a first surface of the sheet-like base material toward a second surface thereof; and a through-hole formed from a bottom of the concavity toward the second surface. Air can escape via this through-hole, allowing a microneedle sheet which is filled with a needle raw material as far as the bottom of the concavity to be obtained. | 08-11-2011 |
20110152792 | MICRONEEDLE ARRAY USING POROUS SUBSTRATE AND PRODUCTION METHOD THEREOF - In order to produce a microneedle array which includes a macromolecular drug such as a vaccine antigen and insulin at its acral portion using a water-soluble thread-forming polymer for a base, there is a need for a substrate which enables a solvent to be efficiently removed so that a base dense solution containing a target substance can be dried and cured while still inserted in a mold. This problem is resolved by using a porous water-insoluble substrate or a porous filter as a substrate, which allows drying and curing as well as peeling from a female mold to be carried out while the base dense solution containing a target substance is still filled in the mold. | 06-23-2011 |
20110127690 | Stamper For Microneedle Sheet, Production Method Thereof, And Microneedle Production Method Using Stamper - Microneedle sheets are produced by injecting a needle raw material into a stamper formed with a concavity in a base material. However, it was not easy to increase the degree of sharpness of the concavity which corresponds to the stamper tips. A method for producing a stamper including the steps of heating a sheet-like base material and an original plate having a conical protrusion, inserting the protrusion of the original plate into the base material to form a conical concavity in the original plate, cooling the original plate with the original plate still inserted in the base material, releasing the original plate from the base material, and heating the base material. | 06-02-2011 |
20080262444 | Percutaneously Absorbable Preparation, Percutaneously Absorbable Preparation Holding Sheet, and Percutaneously Absorbable Preparation Holding Equipment - Self-dissolving needle-like or filamentous shape percutaneously absorbable preparations, by which inherently poorly absorbable drugs into the body through the skin is efficiently administered. The preparations are made of at least one material selected from the group consisting of proteins, polysaccharides, polyvinyl alcohols, carboxyvinyl polymers and sodium polyacrylic acids. An active substance contained therein is released in a sustained-release fashion (1) by forming a water-insoluble layer on its surface, (2) by holding the active substance in porous materials, or (3) by imparting a long-acting characteristic to the active substance. The present invention also provides a sheet-like carrier for holding the preparations on at least one of the sides thereof, and a piece of equipment for holding the preparations so as to facilitate the administration of them. | 10-23-2008 |