BREONICS, INC.
BREONICS, INC. Patent applications | ||
Patent application number | Title | Published |
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20150173348 | ORGAN CHAMBER FOR EX VIVO WARM PERFUSION - An exsanguinous metabolic support system for maintaining an organ or tissue at a near normal metabolic rate is disclosed. The system employs an organ chamber comprising an oxygenator in the perfusion fluid paths for controlling respiratory gases. The oxygenator may contain three pouches for gaseous exchange of the perfusion solution. A controlled gassing subsystem for regulating respiratory gases and maintaining the pH of the perfusion solution is also employed by the system and delivers oxygen and carbon dioxide to the pouches of the oxygenator. The organ chamber additionally includes a perfusion subsystem including the perfusion fluid paths, a container for holding the organ in the perfusion fluid paths with one or more perfusion solution inlets. The organ chamber may additionally include a conduit for receiving venous outflow of perfusion solution and preventing its contact with the outer surfaces of the organ. | 06-25-2015 |
20120179139 | Delivery System for Cell-Based Therapies - A warm perfusion system that has the ability to support a tissue or organ at a near normal metabolic rate provides the mechanism not only for restored oxidative metabolism of the organ but for the delivery of cells, cell-based therapeutics, and growth and differentiation factors to a damaged tissue or organ. Subsequent to delivery of therapeutic cells, such as stem cells or progenitor cells, to the damaged organ, the cells can be prompted to grow, multiply and differentiate, thereby restoring damaged tissue. | 07-12-2012 |