CURATORS OF THE UNIVERSITY OF MISSOURI Patent applications |
Patent application number | Title | Published |
20160063352 | IDENTIFYING GEOGRAPHIC AREAS BASED ON CHANGE PATTERNS DETECTED FROM HIGH-RESOLUTION, REMOTELY SENSED IMAGERY - A method, system, and medium are provided for identifying terrestrial objects that have changed in a certain manner. One embodiment of the method includes receiving a query that includes one or more inputs, which are related to 1) a first terrestrial object (“first object”) and 2) source change-detection information that describes change associated with the first object; applying the query to a dataset that includes indexed information that describes the imagery; based on the one or more inputs, receiving a query result by identifying a set of regions in the dataset that are respectively associated with change information that is similar to that of the source change-detection information; and presenting on a presentation device indications of at least a portion of the identified set of regions. | 03-03-2016 |
20160058907 | BIOMATERIAL COMPOSITIONS - Biomaterial compositions comprising organosilicon monomers (such as silorane monomers) and chemical curing systems or dual chemical/light curing systems, in conjunction with optional tetraoxaspiro[5.5]undecanes (“TOSUs”) and/or fillers. | 03-03-2016 |
20140303226 | KCNQ CHANNELS AS THERAPEUTIC TARGETS - The present disclosure relates to methods and compositions for modulating the activity of KCNQ channels as a means for reducing the effects of aberrant KCNQ channel function associated with epilepsy, deafness and arrhythmias including but not limited to, Long-QT syndrome (“LQTS”), and atrial fibrillation. The present disclosure also relates to the discovery of certain regions of KCNQ channels that interact with various channel stimulating molecules such as, ATP, and PIP | 10-09-2014 |
20140066390 | SACCHARIDE CONJUGATES - The invention provides a series of novel Lipid A anlogues that are structually simple, synthetically accessible, and capable of blocking the cellular receptor within the signal transduction pathway. The novel Lipid A anlogues can include a monosaccharide core with hydrophobic side chains and amino acid ionic motif. The invention further provides methods of using the compounds and compositions thereof in various therapeutic methods. | 03-06-2014 |
20130210953 | BIOMATERIAL COMPOSITIONS - Biomaterial compositions comprising organosilicon monomers (such as silorane monomers) and chemical curing systems or dual chemical/light curing systems, in conjunction with optional tetraoxaspiro[5.5]undecanes (“TOSUs”) and/or fillers. The present invention is directed to biomaterial compositions, as well as methods for manufacturing the same, and methods of using the compositions. The biomaterial composition comprises one or more organosilicon monomers (such as a silorane) and a chemical curing system or dual chemicaVlight curing system for polymerizing the 10 monomer(s). The compositions may include one or more tetraoxaspiro[5.5]undecanes “TOSUs”) and/or fillers. Accelerators (such as photoacids), photosensitizers, and/or electron donors may also be included in the composition as appropriate. | 08-15-2013 |
20110167795 | NANOTHERMITE THRUSTERS WITH A NANOTHERMITE PROPELLANT - In various embodiments, the present disclosure provides a thruster that utilizes a nanothermite material as a propellant. The thruster generally includes a body having at least one sidewall and a bottom wall that define a propellant chamber having a closed repulsion end and an opposing open exhaust end. The thruster additionally includes a nanothermite propellant configured within the propellant chamber to have a selected density that dictates a reaction propagation rate of the nanothermite propellant such that the reaction propagation rate will have a selected one of two distinctly different force-time profiles. | 07-14-2011 |
20100282005 | MASS SENSING DEVICE FOR LIQUID ENVIRONMENT - A device for sensing a mass in a liquid environment including a resonator comprising a piezo layer having a top electrode and a bottom electrode, a sensing surface located adjacent and opposite the top electrode, the resonator and the sensing surface defining a gap therebetween, and a post attached to the sensing surface and the resonator. | 11-11-2010 |
20100233518 | HIGH ENERGY-DENSITY RADIOISOTOPE MICRO POWER SOURCES - A method of constructing a solid-state energy-density micro radioisotope power source device. In such embodiments, the method comprises depositing the pre-voltaic semiconductor composition, comprising a semiconductor material and a radioisotope material, into a micro chamber formed within a power source device body. The method additionally includes heating the body to a temperature at which the pre-voltaic semiconductor composition will liquefy within the micro chamber to provide a liquid state composite mixture. Furthermore, the method includes cooling the body and liquid state composite mixture such that liquid state composite mixture solidifies to provide a solid-state composite voltaic semiconductor, thereby providing a solid-state high energy-density micro radioisotope power source device. | 09-16-2010 |
20100100835 | VISUALIZING GEOGRAPHIC-AREA CHANGE DETECTED FROM HIGH-RESOLUTION, REMOTELY SENSED IMAGERY - A method, system, and medium are provided for presenting aspects of change associated with a geographic area that has been captured by high-resolution, remotely sensed imagery. One embodiment of the method includes receiving a query directed at the geographic area that includes one or more inputs, the query seeking an identification of regions associated with the geographic area that are characterized by aspects of change based on the one or more inputs; applying the query to a dataset of geospatial information that stores imagery associated with the geographic area, wherein the dataset includes information that is sufficient to identify the regions, and wherein the imagery is derived from the high-resolution, remotely sensed imagery, which is characterized by having a resolution of three meters or less per pixel; receiving a first results set that includes a first plurality of keys and corresponding change scores, wherein, (1) each key is useable to identify a certain region, and (2) each change score indicates an amount of change in the certain region from a first state to a second state; and presenting at least a portion of the results set in a viewing application. | 04-22-2010 |
20100100548 | STORING CHANGE FEATURES DETECTED FROM HIGH-RESOLUTION, REMOTELY SENSED IMAGERY - A method, system, and medium are provided for identifying facilitating storage and retrieval of information associated with high-resolution, remotely sensed imagery. In one embodiment, a data structure includes information derived from change-detection information associated with remotely sensed imagery, which change-detection information is useable by the application program, and wherein the data structure includes a plurality of change indexes, each of which (1) indicates change in a given item from a first state to a second state and (2) is associated with a feature set that includes one or more of item-texture features and item-spectral features, wherein each of the change indexes is an entropy balanced statistical (EBS) k-d tree index that describes features associated with items within a geographic area that is reflected in the imagery, and wherein the features include one or more of the item-texture features and item-spectral features. | 04-22-2010 |
20100100540 | REVISING IMAGERY SEARCH RESULTS BASED ON USER FEEDBACK - A method, system, and medium are provided for revising a first set of search results related to high-resolution satellite imagery. One embodiment of the method includes receiving a query that seeks high-resolution, remotely sensed images of geographic areas that have changed consistent with a given change signature; returning indications of the geographic areas; and presenting a first set of images that corresponds to the indications; presenting a set of feedback of options in connection with each of the set of images, wherein the feedback options include one or more of a more-like-this option and a less-like-this option; such that a second set of images can be identified based on receiving input by way of the feedback options. | 04-22-2010 |
20100100539 | IDENTIFYING GEOGRAPHIC-AREAS BASED ON CHANGE PATTERNS DETECTED FROM HIGH-RESOLUTION, REMOTELY SENSED IMAGERY - A method, system, and medium are provided for identifying terrestrial objects that have changed in a certain manner. One embodiment of the method includes receiving a query that includes one or more inputs, which are related to 1) a first terrestrial object (“first object”) and 2) source change-detection information that describes change associated with the first object; applying the query to a dataset that includes indexed information that describes the imagery; based on the one or more inputs, receiving a query result by identifying a set of regions in the dataset that are respectively associated with change information that is similar to that of the source change-detection information; and presenting on a presentation device indications of at least a portion of the identified set of regions. | 04-22-2010 |
20100098342 | DETECTING GEOGRAPHIC-AREA CHANGE USING HIGH-RESOLUTION, REMOTELY SENSED IMAGERY - A method, system, and medium are provided for detecting change in a geographic area. One embodiment includes receiving a set of remotely sensed imagery that depicts the geographic area, automatically identifying changes in physical features of the geographic area by comparing, without user intervention, the set of remotely sensed imagery to a dataset of previously stored remotely sensed imagery that also depicts the geographic area, and deriving a change-quality measurement associated with the set of remotely sensed imagery, wherein the change-quality measurement quantifies a suitability of comparison of the set of remotely sensed imagery to the previously stored remotely sensed imagery. | 04-22-2010 |
20090264306 | DNA METHYLATION BIOMARKERS IN LYMPHOID AND HEMATOPOIETIC MALIGNANCIES - Differential Methylation Hybridization (DMH) was used to identify novel methylation markers and methylation profiles for hematopoieetic malignancies, leukemia, lymphomas, etc. (e.g., non-Hodgkin's lymphomas (NHL), small B-cell lymphomas (SBCL), diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), mantle cell lymphoma (MCL), B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL), chronic lymphocytic leukemia (CLL), multiple myeloma (MM), acute myelogenous leukemia (AML), acute lymphoblastic leukemia (ALL), etc.). Particular aspects provide novel biomarkers for NHL and subtypes thereof (e.g., MCL, B-CLL/SLL, FL, DLBCL, etc.), AML, ALL and MM, and further provide non-invasive tests (e.g. blood tests) for lymphomas and leukemias. Additional aspects provide markers for diagnosis, prognosis, monitoring responses to therapies, relapse, etc., and further provide targets and methods for therapeutic demethylating treatments. Further aspects provide cancer staging markers, and expression assays and approaches comprising idealized methylation and/or patterns” (IMP and/or IEP) and fusion of gene rankings. | 10-22-2009 |