DEPARTMENT OF BIOTECHNOLOGY Patent applications |
Patent application number | Title | Published |
20120244552 | Modified Method of Agglutination to Detect Infections Caused by Microorganisms - Provided herein is a modified method of agglutination to detect infections caused by microorganisms including the steps of staining the test serum, plasma or blood or purified antibodies with a protein stain; mixing serum, plasma or blood with stained antibodies with an equal quantity of colored antigen particles on a glass slide; adding diluted Antiglobulin conjugated with Biotin to the mixture; subjecting the mixture to the step of mixing, adding diluted Avidin (preferably tagged with a visible indicator) to the mixture and thoroughly mixing all the ingredients. | 09-27-2012 |
20120116336 | Device For Collecting Fecal Discharge In Incontinent Patients - A collector for fecal discharge is provided comprising a self-expanding resilient collection component, a housing sheath and a transit component. The collection component has an open proximal and distal end and a lumen connecting them. The component comprises interconnected resilient arms circumscribing its contour, wherein adjacent arms are resiliently biased away from each other for exerting outwardly radial pressure for expanding and anchoring the component to rectal walls upon deployment. The housing sheath comprises a flexible and resilient material overlaying at least one of inner or outer contour of collection component without interfering with or blocking its ends or lumen. The transit component provides a conduit for fecal discharge to migrate from collection component to a receptacle and comprises a flexible, tubular sheath having a first open end connected to a second end by a lumen, wherein the first end engages with the proximal end of the collection component. | 05-10-2012 |
20120106703 | Technique to Enhance the Clinical Efficiency of Radiotherapy and Radiosurgery Using Perturbative Beaming and Tissue-Specific Radiobiology - This invention relates to a technique to enhance the clinical efficiency of radiotherapy and readiosurgery using perturbative beaming and tissue specific radiobiology, comprising, Considering the normal steady beam dose rate, then increasing the temporal stochastic fluctuation of the output intensity of the radiation beam from a medical linear accelerator or cobalt gamma knife beam setup, developing a computer-based methodology by considering the tumor specific radiobiology and magnitude of the tailor made dose rate fluctuation using an embedded system device consisting of requisite hardware and software as described herein. | 05-03-2012 |
20120096573 | Process for Generating Transgenic Animals Using Recombinant Lentiviruses - A process for generating transgenic animals using recombinant lentiviruses. The process comprises injecting recombinant lentiviruses into the interstituim of the testis of a male to produce mature spermatozoa within a few days. The male with transgene expressing lentivirus is mated with a female, forming a progeny carrying the transgene. | 04-19-2012 |
20110286650 | READY AUTOMATED SCREENING, DIAGNOSIS & CLASSIFICATION TECHNIQUE FOR ALZHEIMER'S DISEASE USING MAGNETIC RESONANCE IMAGING SIGNAL FROM VENTRICULAR ZONE CONTOUR OF BRAIN - The invention relates to a fully automated screening, diagnosis and classification technique for Alzheimer's disease using magnetic resonance imaging signals from the ventricular zone contour of the brain to get a fundamental index of brain deterioration comprising the steps: —obtaining a gray scale MRI image of the brain region; —applying a contour edge-detecting algorithm to the image; —employing a grid covering method for calculating a first order metric index of ventricular zone contour; —superimposing metric square grids of increasing edge length to the binary contour image and counting the metric grid squares; —plotting the logs of metric grid squares against the logs of edge lengths, wherein the gradient of the plot is the linear topological metric index. | 11-24-2011 |
20110256547 | MicroRNAa (miRNA) AS BIOMARKERS FOR DIAGNOSING DIFFERENT GRADES OF GLIOMAS AND PATHWAYS OF GLIOMA PROGRESSION - This invention relates to a method for detecting, (i) malignant astrocytoma from normal brain tissue (ii) glioblastoma and anaplastic astrocytoma (iii) primary glioblastoma and secondary glioblastoma (iv) progressive pathway and denovo pathway comprises determining the level of expression of miRNAs listed in table 2, 3, 4, 5, wherein a higher or lower level of expression of miRNAs in the test sample as compared to the control sample differentiates and kit for characterizing a) malignant astrocytoma from normal brain tissue cell comprising reagent capable of specifically detecting the level of expression of the genes of miRNAs and instructions for using said kit for characterizing malignant astrocyoma from normal brain tissue cells b) glioblastoma from anaplastic astrocytoma comprising reagent capable of specifically detecting the level of expression of the genes of miRNAs and instructions for using said kit for characterizing glioblastoma from anaplastic astrocyoma c) primary glioblastoma from secondary glioblastoma comprising reagent capable of specifically detecting the level of expression of the genes of miRNAs and instructions for using said kit for characterizing primary glioblastoma from secondary glioldastoma, d) progressive pathway from denovo pathway comprising reagent capable of specifically detecting the level of expression of the genes of miRNAs and instructions for using said kit for characterizing progressive pathway from denovo pathway. | 10-20-2011 |
20110150932 | Constructing a DNA Chimera for Vaccine Development Against Leishmaniasis and Tuberculosis - A novel recombinant chimera of DNA construct having esat-6 region of | 06-23-2011 |
20110116699 | Medical Image Enhancement Technique Based on Image Transform Resonance - A method for medical image enhancement based on image transform resonance A novel method for Stochastic Resonance of medical image enhancement device based on the Integral Transform of the image, comprising: generating specific types of integral transforms like radon transform for CT, Fourier transform for MRI with image transform component; preparing stochastic perturbation waveform, with perturbator component performing the stochastic resonance on the image transform, with stochastic resonator component; characterizing the image enhancement factor of the SR-processed image with performance monitoring component; adjusting and controlling the bistability parameters of the double-well system that induces stochastic resonance with control component; arranging the provisional display of the array matrix of the SR-enhanced images, as the bistability parameters are varied with matrix display component; subjecting the final image to the step of display with final image display component. | 05-19-2011 |
20110054040 | Bicyclic Triterpenoid Iripallidal as a Novel Anti-Glioma and Anti-Neoplastic Therapy - This invention relates to a Bicyclic triterpenoid Iripallidal as a novel anti-glioma and anti neoplastic agent, having the composition [(−)(6R,10S,11S,18R,22S)-26 Hydroxy-22-α methylcyloirid-16-enal NSC 631939], wherein it binds to Ras GRP3, a phorbol ester receptor that links DAG/phorbolester signaling with Ras activation and induces phosphorylation of ER K1/2 in a Ras dependent manner, reducing proliferation of cancer cell lines to the extent of 50-70%. | 03-03-2011 |
20110046354 | Humanized High Affinity Recombinant Antibody Against Hepatitis B Surface Antigen - This invention relates to a high affinity recombinant humanized antibody fragment (scFv) specific for hepatitis B surface antigen having unique inter/intra chain bonding interaction because of 28 altered amino acid residues from the original mouse (5S) antibody and its chimeric Fab form, wherein fine tuning of the vernier zone residue makes it closer to the human sequence without any structural constraints. | 02-24-2011 |
20110046342 | TUMOR SUPPRESSOR ACTIVATING POLYPEPTIDES AND USES THEREOF - Chimeric tumor suppressor activating peptides derived from matrix attachment region binding protein (MARBP) SMARI unique in their sequence comprising a arginine rich motif flanked by serine residues wherein from the stretch of four consecutive serine residues the first serine residue gets phosphorylated by the protein kinase C family of serine threonine kinases being indispensable for its functionality, the phosphorylation being directly correlated to the phosphorylation of p53 at serine 15 residue thereby stabilizing it, wherein the peptide activates p53 by modifying it post translationally which allow phosphorylation and translocation of p53 to the nucleus. | 02-24-2011 |
20100329989 | In Vivo Labeling of Mammalian Cone Photoreceptors by Intravitreal Injection of Fluorescently Tagged Peanut Agglutinin - A method for specifically labeling of mammalian cone photoreceptors in vivo comprising injecting a mammal with peanut agglutinin conjugated with a fluorescent probe. The peanut agglutinin labels the cone photoreceptor. | 12-30-2010 |
20100311049 | PCR-Based Kit For Detecting Chlamydia Trachomatis and Nelsseria Gonorrhoeae - The invention relates to a PCR based prototype kit for detecting | 12-09-2010 |
20100240071 | Assay for Detection of Transient Intracellular CA2+ - This invention relates to a simple end point assay for detection of transient intracellular Ca | 09-23-2010 |
20100167380 | Process for the Production of Organic Formulation of Bio-Pesticide Pseudomonas Fluorescens - This invention relates to a process for the production of organic formulation of bio pesticide containing | 07-01-2010 |
20100126945 | Reactor for Reductive Conversion Reactions Using Palladized Bacterial Cellulose - A process for affecting reductive conversion reactions in a reactor using the palladized bacterial cellulose immobilized on a support for reductive conversion reactions in a reactor. | 05-27-2010 |
20090305325 | Method for Preservation of Human Hematopoietic Stem or Progenitor Cells - Maintenance of quiescent hematopoietic stem and progenitor cells (HSPC) in culture without the addition of exogenous growth factors is an important aspect in clinical hematology. A recent report described the ability of Flt3 receptor-interacting lectin (FRIL) in the maintenance of cord blood (CB) derived progenitors in vitro. Since FRIL is a mannose binding lectin, the effectiveness of four such lectins of well-characterized specificities on the preservation of HSPC of CB origin have been examined. The HSPC preservation activity of lectins was assessed by in vitro colony forming unit (CFU) and long-term culture initiating cell (LTC-IC) assays. It was found that all four lectins had a HSPC preservation activity at least up to 30 days in culture without addition of exogenous growth factors. The results indicate that use of such lectins may provide a cost effective method of HSPC maintenance for clinical use. | 12-10-2009 |
20090298177 | DAT1 - A synthetic diaminoketothiazole, its process of preparation and its use as a microtubule inhibitor, a probe for tubulin-microtubule system and a cytotoxic agent. Diaminoketothiazole of the formula (I) wherein Ar is 4-OMe-C | 12-03-2009 |
20090291476 | Resistance of Plants to Biotic and Abiotic Stresses by Overexpression of Protochlorophyllide Oxidoreductase C and Its Isoforms - A process for the construction of plant transformation vector comprising: digesting a binary vector pCAMBIA 1304 with EcoRI and Sal I; subjecting the digested binary vector to the step of end filling by Klenow; re-ligating the said binary vector by known method; obtaining CaMV 35 8 promoter cassette with Ω enhancer from pSH9; incorporating the said Camv35S promoter cassette into the Hind III site of the said binary vector to obtain modified pCAMBIA 1304 vector; subjecting pore DNA fragment (1206 bp) to the step of amplification using a pair of primers; introducing EcoRI restriction sites to both the primers; ligating the said amplified cDNA fragment to pGEM T-easy; extracting EcoRI digested porC cDNA fragment from cloned pGEM T-easy; inserting said EcoRI digested porC cDNA fragment into modified pCAMBIA 1304 plant transformation vector to produce recombinant plasmids construct (pCAMBIA 1304-AtporC). | 11-26-2009 |
20090163526 | Process for the Preparation of an Anti Microbial Extract from Leaves of the Plant Callistemon Rigidus - A process for the preparation of an antimicrobial extract from leaves of the plant | 06-25-2009 |
20090018341 | DAT1 - A synthetic diaminoketothiazole, its process of preparation and its use as a microtubule inhibitor, a probe for tubulin-microtubule system and a cytotoxic agent. Diaminoketothiazole of the formula (I) wherein Ar is 4-OMe-C | 01-15-2009 |
20080282431 | Rtbv Plant Promoter And Process Thereof - The present invention relates to isolation and characterization of novel nucleotide sequences from rice tungro bacilliform virus (RTBV) showing promoter activity in plants. The present invention further relates to the analysis of the functional domains of RTBV promoters by fusing full-length and deleted versions of the RTBV promoter sequences with the bacterial reporter gene GUS. The invention also relates to the study of the expression of the reporter gene in various tissues of transgenic rice and tobacco plants during different stages of development. The present invention also describes an RTBV promoter and its deletions which function in a constitutive or tissue-specific manner to drive the expression of the heterologous nucleic acid sequences in both monocot and dicot plants, cells and tissues. | 11-13-2008 |