MAINE MEDICAL CENTER Patent applications |
Patent application number | Title | Published |
20140011737 | COMPOSITIONS AND METHODS FOR REGULATING METABOLISM - The present invention features compositions and methods for treating and preventing a metabolic syndrome featuring the collagen triple helix repeat containing-1 (Cthrc1) protein. | 01-09-2014 |
20130059786 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIAC AND VASCULAR DISEASE - The invention provides methods for the treatment of coronary heart disease, peripheral vascular disease, stroke, and ischemia featuring agents that interfere with the expression or activity of Cthrc1. The invention also provides the use of Cthrc1 peptide as a therapeutic agent for the treatment of acute or chronic cardiac deficiencies. The invention further provides detection and monitoring of Cthrc1 peptide in blood or serum to assess or monitor cardiac function. | 03-07-2013 |
20120237504 | COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION AND FIBROSIS - The present invention features compositions featuring agents that bind to denatured collagen and methods of using such agents to treat or prevent fibrosis or inflammation in a subject. | 09-20-2012 |
20120203051 | TREATMENT OF CANCER USING THE SODIUM SALT OF A BENZOIC ACID DERIVATIVE - The present invention provides a method of treating cancer using the sodium salt of a benzoic acid derivative, alone or in combination with standard treatments such as chemotherapy and radiotherapy. | 08-09-2012 |
20110165697 | MONOCLONAL ANTIBODIES AGAINST OSTEOPONTIN - The present invention relates to reagents and methods for the detection of osteopontin fragments and distinguishing them from each other and from the full-length osteopontin protein. The present invention also relates to assays for the determination of the presence of osteopontin fragments in samples obtained from subjects and, further, the correlation of osteopontin fragment levels fragment levels with disease detection, progression and prognosis. | 07-07-2011 |
20110125467 | SYSTEM FOR OPTIMIZING TREATMENT STRATEGIES USING A PATIENT-SPECIFIC RATING SYSTEM - The combined effects of a selected treatment option on multiple causes of morbidity or mortality are simulated for evaluation. Various patient-specific and model-specific parameters, including parameters related to diseases to be modeled, are used in modeling incidence and mortality rates for each disease. These disease-specific models are used for defining a set of health states having initial probabilities, which are used to formulate a transition matrix used in matrix calculation to obtain output matrix Q. If additional cycles are needed, the transition matrix is updated and matrix calculation is performed using the updated transition matrix. Otherwise, final output matrix Q is utilized for calculation of values needed for determining an overall treatment score. The calculated values and/or values from Q are combined with patient or numeric scores from other treatment choice-related domains to obtain a raw score that is used to produce a patient-specific score for a selected treatment option. | 05-26-2011 |