PNEUMATIC SCALE CORPORATION Patent applications |
Patent application number | Title | Published |
20130089917 | Single Use Centrifuge System for Highly Concentrated and/or Turbid Feeds - A method and apparatus for cell harvest of production scale quantities of cell cultures using single use components comprising a flexible membrane mounted on a rigid frame and is supported within a multiple use rigid centrifuge bowl, such single use components including a core with an increased diameter and an internal truncated cone shape in order to permit the system to maintain a sufficiently high angular velocity to create a settling velocity suited to efficiently processing highly concentrated cell culture streams. Features which minimize feed turbidity, and others which permit the continuous or semi-continuous discharge of cell concentrate, increase the overall production rate over the rate which can be achieved using current intermittent processing methods for large cell culture volumes. Injection of a diluent during the cell concentrate removal process permits more complete removal of viscous cell concentrates. | 04-11-2013 |
20130012371 | Centrifuge System and Method - A centrifuge may include a bowl operative to rotate with respect to a stationary portion. The centrifuge may include at least one vibration sensor operative to generate vibration data representative of vibrational movement of portions of the centrifuge. The processor may monitor the vibration data as the bowl is being filled with a fluid. The processor may cause a drive device to increase the rotational speed of the bowl responsive to determining from the vibration data that the bowl has becoming substantially filled with a fluid. | 01-10-2013 |
20100167388 | Single Use Centrifuge System - An improved centrifuge system having a single means for both feeding and collecting liquid streams aseptically from rotating components is provided. Also methods and apparatus for centrifugal separation of cells from cell culture media of large cell culture batches by processing a large volume within a few hours, using pre-sterilized, single-use fluid path components. The apparatus uses a sealing approach that improves reliability while avoiding air contamination as well as shedding from mechanical seals. The risk of process liquid leaks is minimized. | 07-01-2010 |