The Royal Institution for the Advancement of Learning / McGill University Patent applications |
Patent application number | Title | Published |
20150236353 | FABRICATION AND FUNCTIONALIZATION OF A PURE NON-NOBLE METAL CATALYST STRUCTURE SHOWING TIME STABILITY FOR LARGE SCALE APPLICATIONS - A pure and crystalline single-crystal nitrogen-functionalized graphene nano-flake powder comprising from 2 atomic % to at least 35 atomic % of total functionalized nitrogen within the graphene nano-flakes is disclosed. As well, the method of producing the nano-flakes that comprises injecting a carbon source into a thermal plasma system, dissociating the carbon source into carbon atomic species, transporting the carbon atomic species through a controlled nucleation zone to produce a crystalline graphene nano-flake structure, injecting the nitrogen source into the thermal plasma system dissociating the nitrogen source into nitrogen active species, and transporting the nitrogen atomic species to contact the crystalline graphene nano-flakes to produce the crystalline nitrogen-functionalized graphene nano-flakes is also disclosed. Finally, a multilayer composite comprising a carbon substrate and a layer of crystalline nitrogen-functionalized graphene nano-flakes is also described. | 08-20-2015 |
20150157376 | METHOD OF PRODUCING A POROUS BONE SCREW - A bone screw and method of producing the same is described. The method of producing a bone screw includes forming a one-piece headless screw body out of a rigid metallic foam that is entirely porous throughout and defines a plurality of inter-connected pores having a size of about 30 to about 500 microns in diameter. The method includes providing at least one thread on an external surface of the screw body, and forming a bore extending through an entire axial length of the screw body, the bore forming a cannula that defines an annular radial wall thickness of the screw body. The method further includes disposing the inter-connected pores throughout the radial wall thickness of the screw body such as to allow for bone in-growth through the full radial wall thickness and into the cannula. | 06-11-2015 |
20140265720 | METHODS AND DEVICES RELATING TO CAPACITIVE MICROMACHINED DIAPHRAGMS AND TRANSDUCERS - Monolithically integrated capacitive micromachined transducers (CMTs) offer combined process steps, shared layers, simplified packaging, and reduced die size by overlapping the CMTs with the integrated circuit (IC) electronics. Moreover, a CMT array directly above the electronics also allows for varying the excitation signal phase to each CMT element thereby enabling beam-forming techniques. Above-IC integration is particularly attractive by not requiring any alteration of the semiconductor fabrication process and allowing subsequent implementation independent of IC fabrication. Naturally, this scheme requires that the CMT technology limit itself to IC compatible materials and chemicals, as well as process step temperatures within a specific thermal budget. Embodiments of the invention expanding upon surface micromachining technology allow the fabrication of IC-compatible CMT structures with superior mechanical properties and resistance to harsh environments such as high temperature, corrosive media and high-g shocks, by exploiting silicon carbide (SiC) structures to form the upper CMT structural layer. | 09-18-2014 |
20140230547 | Microelectromechanical Bulk Acoustic Wave Devices and Methods - Micromachined gyroscopes, such as those based upon microelectromechanical systems (MEMS) have the potential to dominate the rate-sensor market mainly due to their small size, low power and low cost. As MEMS gyroscopes are resonant devices requiring active excitation it would be beneficial to improve the resonator Q-factor reducing the electrical drive power requirements for the excitation circuitry. Further, many prior art MEMS gyroscope designs have multiple resonances arising from design and manufacturing considerations which require additional frequency tuning and control circuitry together with the excitation/sense circuitry. It would therefore be beneficial to enhance the bandwidth of the resonators to remove the requirement for such circuitry. Further, to address the relatively large dimensions of MEMS gyroscopes it would be beneficial for the MEMS gyroscopes to be fabricated directly above the CMOS electronics thereby reducing the die dimensions and lowering per die cost. | 08-21-2014 |
20140219279 | METHODS AND SYSTEMS FOR NETWORK ADDRESS LOOKUP ENGINES - Internet routers are a key component in today's Internet. Each router forwards received packets toward their final destinations based upon a Longest Prefix Matching (LPM) algorithm select an entry from a routing table that determines the closest location to the final packet destination among several candidates. Prior art solutions to LPM lookup offer different tradeoffs and that it would be beneficial for a design methodology that provides for low power large scale IP lookup engines addressing the limitations within the prior art. According to embodiments of the invention a low-power large-scale IP lookup engine may be implemented exploiting clustered neural networks (CNNs). In addition to reduced power consumption embodiments of the invention provide reduced transistor count providing for reduced semiconductor die footprints and hence reduced die cost. | 08-07-2014 |
20140114430 | STENT DEVICES MADE OF A LATTICE WITH SMOOTH SHAPE CELLS IMPROVING STENT FATIGUE LIFE - A method for generating a lattice cell shape for a stent comprising generating a unit cell model representing a stent cell to be made of a given material, the unit cell model comprising elements each comprising points defining a G | 04-24-2014 |
20140094924 | ORTHOPAEDIC IMPLANTS - A method for making an orthopaedic implant, the method comprising: characterizing at least a portion of a bone corresponding to the bone to be replaced, said corresponding bone being on the contralateral side of the patient; providing a model of the orthopaedic implant based on a mirror image of the contralateral bone; and forming the orthopaedic implant based on the model. | 04-03-2014 |
20140092469 | Method and System for Optical Microscopy - Optical microscopy of biological specimens, particularly live cells, is difficult as they generally lack sufficient contrast to be studied successfully as typically the internal structures of the cell are colourless and transparent. Commonly, contrast is increased by staining the different structures with selective dyes, but this involves killing and fixing the sample. Staining may also introduce artifacts, apparent structural details caused by the processing of the specimen and are thus not a legitimate feature of the specimen. Further, microscopy of different elements of these biological specimens typically requires multiple microscopy techniques on multiple specimens. According to embodiments of the invention simultaneous imaging techniques are applied to a biological specimen such as fluorescent imaging and dark field imaging by designing an experimental evaluation system and associated illumination system addressing the conflicting demands of these approaches. | 04-03-2014 |
20140080225 | METHODS AND DEVICES FOR XEROGEL BASED SENSORS - Fluorescence based sensing systems and methods that exploit xerogels are provided. Embodiments of the invention encompass a sensing system that includes: an optical excitation source emitting over a first predetermined wavelength range and capable of analog modulation over a predetermined frequency range; a sensor including a gel substrate incorporating within its matrix a receptor for molecular recognition of an analyte and a luminophore for signaling a recognition event relating to the analyte, the luminophore emitting an optical signal over a second predetermined wavelength range; a detection circuit including an optical detector for receiving the optical signal emitted by the luminophore and generating a photocurrent in dependence thereof; an excitation circuit that generates an analog signal for modulating the optical excitation source in dependence upon a digital control; and a read circuit for receiving the photocurrent and generating a digital output. | 03-20-2014 |
20130315948 | CONTROLLED RELEASE FORMULATION BASED ON HEMATIN ANHYDRIDE CRYSTALS FOR THE INDUCTION OF AN INNATE IMMUNE REACTION - The present invention relates to a new process for producing a doped synthetic monodispersed hematin anhydride (HA) crystals useful as a slow release vehicle and immune modulator. As the preparation comprises embedded in the crystals one or more antigens and/or one or more biologically active entities, the preparation can be useful in numerous medical indications such as vaccine or any therapy where it is desired that a biologically active entity maintains its activity over time due to its slow-release. The process comprises the steps of (i) providing a substantially pure iron(III) protoporphyrin-IX, in solution in an alkaline solution substantially free of oxygen (ii) adjusting the pH of the solution to an acidic pH of between about 4.0, by slowly adding a medium strong organic acid, (iii) during step b) above, adding one or more antigens and/or one or entities having a biological activity, at a pH of about 5.0. | 11-28-2013 |
20130300483 | METHODS AND DEVICES RELATING TO TIME-VARIABLE SIGNAL PROCESSING - Time-Mode Signal Processing (TMSP) offers a means for offsetting some of the challenges for analog circuit designs when exploiting CMOS circuit processes designed for digital applications. It would therefore be beneficial to provide a digital method for the storage, addition and subtraction of Time-Mode variables as these offer significant benefit to providing TMSP techniques and expanding their exploitation within devices, systems, and applications. Whilst driven by CMOS process challenges the TM circuits outlined may exploit essentially any digital circuit technology since they are based upon delay. The inventors present an approach to TM variables wherein a switched delay unit is exploited and adopted such that the instantaneous phase difference between two rising signal edges can be latched and used to perform various arithmetic operations. Beneficially, the technique allows analog sampled-data signal processing to be implemented within digital circuitry. | 11-14-2013 |
20130255361 | Methods and Devices for Multi-Dimensional Separation, Isolation and Characterization of Circulating Tumour Cells - In most cancers, a significant factor in a poor outcome for the individual cancer victim is metastatic disease, i.e., dissemination of tumour cells to other parts of the human body via the circulation, such as distant organs, and their subsequent proliferation therein to form multiple other cancer tumours. The presence of circulating tumour cells, or CTCs, represents a vital intermediate step in this process and variations of a few CTCs within blood samples containing tens of billions of cells may denote the outcome for a patient or impact the cancer treatment regimen. At present no low cost field deployable technique for filtering CTCs exists. According to embodiments of the invention micro-machined filters with high aspect ratio, with and without, functionalization are employed to perform multi-parameter filtering for CTCs based upon compatibility with low cost semiconductor processes within multiple materials including silicon, polymers and silicon carbide. | 10-03-2013 |
20130240348 | High Efficiency Broadband Semiconductor Nanowire Devices - Amongst the candidates for very high efficiency electronics, solid state light sources, photovoltaics, and photoelectrochemical devices, and photobiological devices are those based upon metal-nitride nanowires. Enhanced nanowire performance typically require heterostructures, quantum dots, etc which requirement that these structures are grown with relatively few defects and in a controllable reproducible manner. Additionally flexibility according to the device design requires that the nanowire at the substrate may be either InN or GaN. Methods of growing relatively defect free nanowires and associated structures for group IIIA-nitrides are presented without the requirement for foreign metal catalysts, overcoming the non-uniform growth of prior art techniques and allowing self-organizing quantum dot, quantum well and quantum dot-in-a-dot structures to be formed. Such metal-nitride nanowires and quantum structure embedded nanowires support a variety of devices including but not limited to very high efficiency electronics, solid state light sources, photovoltaics, and photoelectrochemical devices, and photobiological devices. | 09-19-2013 |
20130236153 | METHOD OF MANUFACTURING OPTICAL FIBERS, TAPERED OPTICAL FIBERS AND DEVICES THEREOF - Optical fibers and optical fiber tapers have application within many optical systems and optical devices. To date manufacturing such fibers and fiber tapers has been restricted to drawing constant diameter fibers in gravity driven processes and symmetric tapers through pulling with localized heating. However, it would be beneficial to be able to generate arbitrary profiles when pulling an optical fiber into a fiber taper allowing an initial uniform section, reducing transition, wire section, increasing transition and final uniform section. Further, the technique further allows novel optical fiber geometries to be fabricated, which the inventors refer to a hybrid tapers wherein additional elements such as coatings, which provide mechanical and environment protection, may be incorporated into the initial preform and processed simultaneously with the fabrication of the optical taper such that the final fabricated hybrid tapers are mechanically robust and handlable thereby improving manufacturing yield and reducing cost. | 09-12-2013 |
20130115730 | Low-Temperature Wafer Level Processing for MEMS Devices - It would be beneficial to integrate MEMS devices with silicon CMOS electronics, package them in controlled environments, e.g. vacuum for MEMS resonators, and provide industry standard electrical interconnections such as solder bumps. However, to do so requires through-wafer via-based electrical interconnections. However, the fragile nature of the MEMS devices, the requirement for vacuum, hermetic sealing, and the stresses placed on metallization membranes are not present in conventional CMOS packaging. Accordingly there is provided a means of reinforcing through-wafer vias for integrated MEMS-CMOS circuits by in-filling the through-wafer electrical vias with low temperature deposited ceramic materials deposited with processes compatible with post-processing of CMOS electronics. Beneficially ceramics such as silicon carbide provide enhanced mechanical strength, enhanced expansion matching, and increased thermal conductivity in comparison to silicon and solder materials. The ceramic reinforcing may be further adapted to include micro-channels for the provisioning of liquid cooling through the structures. | 05-09-2013 |
20130087890 | METHOD FOR FABRICATING OPTICAL SEMICONDUCTOR TUBES AND DEVICES THEREOF - Semiconductor micro- and nanotubes allow the incorporation of ordered structures such as quantum wells and quantum dots into them providing the potential for ultralow threshold micro- and nanoscale lasers for use in applications such as future ultrahigh-speed photonic systems as well as quantum information processing. According to the invention a means of manufacturing these with high reproducibility, low processing complexity, and at high densities is provided. Also provided is a means of releasing these micro- and nanotubes with low stress and a method of “pick-and-place” allowing micro- and nanotubes to be exploited in devices integrated on substrates that are either incompatible with the manufacturing technique or where the area of substrate required to manufacture them is detrimental to the cost or performance of the circuit. | 04-11-2013 |
20130085251 | POLYMERS AND COPOLYMERS CONTAINING 2H-BENZIMIDAZOL-2-ONE MOIETIES - Polymers and copolymers containing 1H-benzo[d]imidazol-2(3H)-one units have been synthesized under conditions generally used for the synthesis of poly(aryl ether)s. 1H- | 04-04-2013 |
20130053273 | METHODS AND DEVICES FOR MULTIPLEXED MICROARRAY MICROFLUIDIC ANALYSIS OF BIOMOLECULES - Rapid and specific detection of biological cells and biomolecules is important to biological assays across diverse fields including genomics, proteomics, diagnoses, and pathological studies. Microarrays and microfluidics increasingly dominate such detection techniques due to the ability to perform significant numbers of tests with limited sample volumes. A snap chip assembly is provided for the transfer of a microarray of reagents within semi-spherical liquid droplets on a transfer chip to a target assay microarray on an assay chip following assembly of the two chips and physical contact of the droplets with the target array. Reagents in nanolitre quantities are spotted on both chips and selectively transferred as liquid droplets between transfer chip and assay chip within the contact areas. Using the snap chip structure the inventors performed immunoassays with colocalization of capture and detection antibodies with 10 targets and bead-in-gel droplet microarrays with 9 targets in the low pg/ml regime. | 02-28-2013 |
20120231411 | DENTAL PROBE WITH CURETTE - There is described a hand-held dental instrument for detection of carious lesions which includes a handle portion defining a longitudinal axis therethrough and at least a first working end, mounted on the handle portion, which includes a probe body extending from the handle portion and a probe tip disposed at a remote end. The probe tip is configured for exploring teeth and/or periodontal pockets. The probe body is curved and has a curette portion disposed on the probe body between the handle portion and the probe tip, the curette portion having at least two scraping fins each defining a curved blade for removing at least one of biofilm, plaque and tartar from a curved tooth surface. | 09-13-2012 |
20120205613 | High Efficiency Broadband Semiconductor Nanowire Devices and Methods of Fabricating without Foreign Catalysis - Amongst the candidates for very high efficiency solid state light sources and full solar spectrum solar cells are devices based upon InGaN nanowires. Additionally these nanowires typically require heterostructures, quantum dots, etc which all place requirements for these structures to be grown with relatively few defects and in a controllable reproducible manner. Additionally flexibility according to the device design requires that the nanowire at the substrate may be either InN or GaN. According to the invention a method of growing relatively defect free nanowires and associated structures for group IIIA-nitrides is presented without the requirement for foreign metal catalysts and overcoming the non-uniform growth of prior art non-catalyst growth techniques. According to other embodiments of the invention self-organizing dot-within-a-dot nanowire and dot-within-a-dot-within-a-well nanowire structures are presented. | 08-16-2012 |
20120179636 | Method and System for Automatically Classifying and Identifying Vestibulo-Ocular Responses - Stabilizing the visual system for any sighted mobile system increases immunity of the mobile system's gaze and reduces information processing task complexity. Two human reflexes are the optokinetic reflex and vestibulo-ocular reflex (VOR). The VOR stabilizes retinal images during head movement by producing eye movements in the opposite direction. Improved analysis of the VOR in humans would improve the diagnosis/treatment of patients, provide improvements in visual prosthesis performance for patients, and also vision systems performance for mobile robotic systems. However, an important issue for prior art mathematical analysis techniques is the requirement to classify the nystagmus segments before applying any analysis techniques, wherein this classification should be preferably performed non-subjectively. Accordingly the inventors overcome these limitations by performing classification, i.e. segmentation of the data record into multiple modes (including possible artifacts or outliers), and identification of mode dynamics concurrently and objectively in a manner suitable for multi-input systems. | 07-12-2012 |
20110282828 | METHOD OF IDENTIFICATION AND DEVICES THEREOF - Portable wireless devices are ubiquitous in modern society and many of these have integral sensors such as accelerometers, microphones, and Global Positioning Systems (GPS) that can collect data. This creates potential for intelligent applications to recognize the user, or aspects of the user and take appropriate action. According to embodiments of the invention there are presented techniques for representing such time series data which reduce the memory and computational complexity of performing the analysis and classifying the results. The techniques exploit time-delay embedding is to reconstruct the state and dynamics of an unknown dynamical system, Geometric Template Matching to build nonparametric classifiers, and algorithms to address the problem of selecting segments of data from which to build the time-delay models for classification problems. | 11-17-2011 |
20110271411 | METHOD AND APPARATUS FOR MEASURING CANTILEVER DEFLECTION IN CONSTRAINED SPACES - Atomic Force Microscopes (AFMs) allow forces within systems under observation to be probed from the piconewton forces of a single covalent bond to the forces exerted by cells in the micronewton range. The pendulum geometry prevents the snap-to-contact problem afflicting soft cantilevers in AFMs which enable attonewton force sensitivity. However, the microscopic length scale studies of cellular/subcellular forces parallel to the imaging plane of an optical microscope requires high sensitivity force measurements at high sampling frequencies despite the difficulties of implementing the pendulum geometry from constraints imposed by the focused incoming/outgoing light interfering with the sample surface. Additionally measurement systems for biological tissue samples in vitro must satisfy complex physical constraints to provide access to the vertical cantilever. Embodiments of the invention address these geometrical restrictions by exploiting optical periscope approaches that further allows multiple probes to be deployed and multiple optical beams within each probe. | 11-03-2011 |
20110231731 | METHOD AND SYSTEM FOR DECODING - Low-Density Parity-Check (LDPC) codes offer error correction at rates approaching the link channel capacity and reliable and efficient information transfer over bandwidth or return-channel constrained links with data-corrupting noise present. LDPC codes also offer error correction performance approaching channel capacity exponentially fast in terms of the code length, linear processing complexity, and parallelism that scales with the code length. They also offer challenges relating to the decoding complexity of the binary error-correction codes themselves and error floors limiting achievable bit-error rates. A new Relaxed Half-Stochastic (RHS) decoding algorithm is presented that reduces decoding complexity for high decoding throughput applications. The RHS algorithm uses an approach based on stochastic decoding algorithms but differs significantly from the conventional approaches of LDPC decoder implementation. The RHS algorithm also leads to a randomized decoding technique called redecoding that addresses the error floor limitation. | 09-22-2011 |
20110163421 | Method for Fabricating Optical Semiconductor Tubes and Devices Thereof - Semiconductor micro- and nanotubes allow the incorporation of ordered structures such as quantum wells and quantum dots into them providing the potential for ultralow threshold micro- and nanoscale lasers for use in applications such as future ultrahigh-speed photonic systems as well as quantum information processing. According to the invention a means of manufacturing these with high reproducibility, low processing complexity, and at high densities is provided. Also provided is a means of releasing these micro- and nanotubes with low stress and a method of “pick-and-place” allowing micro- and nanotubes to be exploited in devices integrated on substrates that are either incompatible with the manufacturing technique or where the area of substrate required to manufacture them is detrimental to the cost or performance of the circuit. | 07-07-2011 |
20110127490 | Method of Growing Uniform Semiconductor Nanowires without Foreign Metal Catalyst and Devices Thereof - Amongst the candidates for very high efficiency solid state lights sources and full solar spectrum solar cells are devices based upon InGaN nanowires. Additionally these nanowires typically require heterostructures, quantum dots, etc which all place requirements for these structures to be grown with relatively few defects. Further manufacturing requirements demand reproducible nanowire diameter, length etc to allow these nanowires to be embedded within device structures. Additionally flexibility according to the device design requires that the nanowire at the substrate may be either InN or GaN. According to the invention a method of growing relatively defect free nanowires and associated structures for group III—nitrides is presented without the requirement for foreign metal catalysts and overcoming the non-uniform growth of prior art non-catalyst growth techniques. The technique also allows for unique dot-within-a-dot nanowire structures. | 06-02-2011 |
20110111545 | LOW TEMPERATURE CERAMIC MICROELECTROMECHANICAL STRUCTURES - A method of providing microelectromechanical structures (MEMS) that are compatible with silicon CMOS electronics is provided. The method providing for processes and manufacturing sequences limiting the maximum exposure of an integrated circuit upon which the MEMS is manufactured to below 350° C., and potentially to below 250° C., thereby allowing direct manufacturing of the MEMS devices onto electronics, such as Si CMOS circuits. The method further providing for the provisioning of MEMS devices with multiple non-conductive structural layers such as silicon carbide separated with small lateral gaps. Such silicon carbide structures offering enhanced material properties, increased environmental and chemical resilience whilst also allowing novel designs to be implemented taking advantage of the non-conductive material of the structural layer. The use of silicon carbide being beneficial within the formation of MEMS elements such as motors, gears, rotors, translation drives, etc where increased hardness reduces wear of such elements during operation. | 05-12-2011 |
20110024771 | Optically Interrogated Solid State Biosensors Incorporating Porous Materials - Devices and Methods of Fabrication - Quantitative understanding of neural and biological activity at a sub-millimeter scale requires an integrated probe platform that combines biomarker sensors together with electrical stimulus/recording sites. Optically addressed biomarker sensors within such an integrated probe platform allows remote interrogation from the activity being measured. Monolithic or hybrid integrated silicon probe platforms would beneficially allow for accurate control of neural prosthetics, brain machine interfaces, etc as well as helping with complex brain diseases and disorders. According to the invention a silicon probe platform is provided employing ultra-thin silicon in conjunction with optical waveguides, optoelectronic interfaces, porous filter elements, and integrated CMOS circuitry. Such probes allowing simultaneously analysis of both neural electrical activities along with chemical activity derived from multiple biomolecular sensors with porous membrane filters. Such porous silicon and polymer filters providing biomolecular filtering and optical filtering being compatible with post-processing wafers with integrated CMOS electronics. | 02-03-2011 |
20100074381 | METHODS AND SYSTEMS FOR IMPROVING ITERATIVE SIGNAL PROCESSING - A method for iteratively decoding a set of encoded samples received from a transmission channel is provided. A data signal indicative of a noise level of the transmission channel is received. A scaling factor is then determined in dependence upon the data signal and the encoded samples are scaled using the scaling factor. The scaled encoded samples are then iteratively decoded. Furthermore, a method for initializing edge memories is provided. During an initialization phase initialization symbols are received from a node of a logic circuitry and stored in a respective edge memory. The initialization phase is terminated when the received symbols occupy a predetermined portion of the edge memory. An iterative process is executed using the logic circuitry storing output symbols received from the node in the edge memory and a symbol is retrieved from the edge memory and provided as output symbol of the node. Yet further an architecture for a high degree variable node is provided. A plurality of sub nodes forms a variable node for performing an equality function in an iterative decoding process. Internal memory is interposed between the sub nodes such that the internal memory is connected to an output port of a respective sub node and to an input port of a following sub node, the internal memory for providing a chosen symbol if a respective sub node is in a hold state, and wherein at least two sub nodes share a same internal memory. | 03-25-2010 |