UNIVERSITAET LEIPZIG Patent applications |
Patent application number | Title | Published |
20150274781 | POTENT LIGANDS OF THE GHRELIN RECEPTOR - The present invention relates to highly potent ligands at the ghrelin receptor to influence food intake or other conditions. | 10-01-2015 |
20150259338 | PRECURSOR COMPOUNDS FOR THE RADIOSYNTHESIS OF [18F] NORCHLORO-FLUOROHOMOEPIBATIDINE - The invention relates to a compound of formula Ia or Ib wherein R | 09-17-2015 |
20140346058 | DEVICE AND METHOD FOR PARALLEL RECORDING OF IMPEDANCE SPECTRA AND FIELD POTENTIAL - The present invention relates to a device and a method for parallel recording of impedance spectra and field potential of cells in vitro. | 11-27-2014 |
20140309300 | Bicyclic Labdane Diterpenes for Use in the Treatment of TRPC6 Associated Diseases - The present invention relates to bicyclic labdane diterpenes for use in the treatment of a disease associated with activation of transient receptor potential cation channel 6 (TRPC6), preferably a pulmonary or a renal disease. In one aspect the invention relates to the use of a bicyclic labdane diterpene for blocking calcium transport via TRPC6. Another aspect of the invention is a bicyclic labdane diterpene according to formula (1) for use as a medicament wherein R | 10-16-2014 |
20140162306 | POLYMUTANT TAU PROTEIN VARIANTS AND THEIR USE FOR RECAPITULATING HUMAN TAUOPATHIES - The present invention relates to a tau protein comprising at least four different mutations selected from group consisting of mutations which cause the condition frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17), and to nucleic acids encoding said tau protein. The invention further pertains to methods for identifying an agent for treating or preventing neurogenerative disease, and to methods for recapitulating tauopathies. | 06-12-2014 |
20130217064 | Integrated cultivation and measurement device for label-free detection and classification of cellular alterations, in particular for generation and characterisation of cell-spheroids, components and uses thereof - The invention relates to an integrated cultivation and measurement device for label-free detection and classification of cellular alterations, in particular for generation and characterisation of cell-spheroids and monitoring the condition of the cell-spheroids in real time, comprising a) a mounting device for a cultivation chamber plate, b) an amplifier board linked with the contacts for the microelectrodes in the mounting device, c) a rotary shaker, on which the amplifier board and the mounting device for the cultivation chamber plate are placed, and d) a control unit, that is linked with the amplifier board and the rotary shaker, wherein the control unit allows recording, analyzing of data and controlling of the movement of the rotary shaker. The cultivation chamber plate has several culture reservoirs, wherein the bottom of each culture reservoir forms a microcavity and each microcavity features microelectrodes on the microcavity walls. The mounting device has contacts for the microelectrodes. The invention advantageously allows the automated generation, cultivation and characterisation of spheroids, as well as the cultivation and characterisation of tissue probes. | 08-22-2013 |
20130017607 | Nanotube carrier substrate for primary tissue cultureAANM Mayr; StefanAACI LeipzigAACO DEAAGP Mayr; Stefan Leipzig DEAANM Zink; MareikeAACI LeipzigAACO DEAAGP Zink; Mareike Leipzig DEAANM Dallacasagrande; ValentinaAACI LeipzigAACO DEAAGP Dallacasagrande; Valentina Leipzig DEAANM Kas; JosefAACI LeipzigAACO DEAAGP Kas; Josef Leipzig DEAANM Reichenbach; AndreasAACI LeipzigAACO DEAAGP Reichenbach; Andreas Leipzig DE - A carrier substrate for primary tissue culture has a nanotube array. A tissue culture vessel has an outer vessel and a nanotube carrier substrate with a nanotube array, located within the outer vessel, wherein the surface roughness of the nanotube array is 1 nm to 100 nm. The nanotube array is used for in vitro culturing of primary tissue in connection with a tissue culture vessel for in vitro culturing of primary tissue and a method for in vitro culturing primary tissue, wherein a nanotube array is arranged essentially horizontal inside an outer cell culture vessel, so that openings of the nanotubes point at least in upward direction, the nanotube array is contacted with cell culture medium and an isolated primary tissue sample is placed on top-side on said nanotube array. | 01-17-2013 |
20120091453 | Transparent Rectifying Metal/Metal Oxide/Semiconductor Contact Structure and Method for the Production Thereof and Use - The invention relates to transparent rectifying contact structures for application in electronic devices, in particular appertaining to optoelectronics, solar technology and sensor technology, and also a method for the production thereof. The transparent rectifying contact structure according to the invention has the following constituents: a) a transparent semiconductor, b) a transparent, non-insulating and non-conducting layer composed of metal oxide, metal sulphide and/or metal nitride, the resistivity of which is preferably in the range of 10 | 04-19-2012 |