WAKUNAGA PHARMACEUTICAL CO. LTD Patent applications |
Patent application number | Title | Published |
20130190363 | THERAPEUTIC AGENT FOR NEUROLOGICAL DISEASES - An object of the present invention is to provide a pharmaceutical agent useful for treating and preventing neurological disease, having satisfactory solubility and oxidative stress-mediated cell death suppressive activity as well as capable of exhibiting excellent blood-brain barrier permeability. The present invention is directed to an acylaminoimidazole derivative represented by general formula (I) or a salt thereof, and a pharmaceutical and a therapeutic or preventive agent for neurological disease containing the same, as an active ingredient. | 07-25-2013 |
20120308656 | SUGAR-COATED PREPARATION AND PRODUCTION METHOD FOR THE SAME - A method is provided for producing a sugar-coated preparation including a solid composition containing a pharmacologically active ingredient and a sugar coating layer. The method comprises a step of forming the sugar coating layer with a sugar coating composition containing one or more sugar-alcohols selected from the group consisting of mannitol and erythritol and a polyvinyl alcohol-based resin. The sugar-coated preparation includes a solid composition containing a pharmacologically active ingredient and a sugar coating layer, wherein the sugar coating layer is made of a sugar coating composition containing one or more sugar-alcohols selected from the group consisting of mannitol and erythritol and a polyvinyl alcohol-based resin. | 12-06-2012 |
20100285147 | CRUDE DRUG EXTRACT-BLENDED LIQUID MEDICINE - Provided an acidic liquid preparation containing a herb and/or animal-origin extract at high concentration to suppress time-dependent occurrence of precipitation and/or opacity. | 11-11-2010 |
20100063098 | PYRIDONE DERIVATIVES AS P38A MAPK INHIBITORS - A compound represented by the formula (I): wherein R | 03-11-2010 |
20090149440 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF - The present invention provides an agent which exhibits excellent antibacterial activity, low toxicity, improved bioavailability, and low binding rate to serum proteins. The present invention is directed to a pyridonecarboxylic acid derivative represented by formula (1): | 06-11-2009 |
20090042856 | PYRIDAZINONE DERIVATIVES USED FOR THE TREATMENT OF PAIN - A pyridazinone derivative compound shown by the following formula (I): wherein R | 02-12-2009 |
20090012054 | Cephem Compounds and Use as Antimicrobial Agents - The present invention provides a compound of the formula [I]: wherein R1 is lower alkyl, etc. and R2 is hydrogen, etc., or R1 and R2 are bonded together to form lower alkylene; R3 is a group represented by wherein R6 and R7 are independently optionally protected amino, etc.; m and n are independently an integer of 0 to 6; R8 and R9 are independently optionally protected amino, etc., and q and r are independently an integer of 0 to 6, or R8 and R9, together with the adjacent alkylene(s) and the nitrogen atom, form saturated nitrogen-containing heterocycle optionally having substituent(s); R4 is lower alkyl, etc.; and R5 is amino, etc., or a pharmaceutically acceptable salt thereof. | 01-08-2009 |
20080311571 | Nucleic Acid Fragments for Detecting Nucleic Acid and Method for Detecting Nucleic Acid - A nucleic acid fragment set according to the present invention comprises a plural number of nucleic acid fragments capable of individually hybridizing with a plural number of target sequences, in which each nucleic acid fragment has a region ligatable with each other and the affinity between such ligatable regions is adjusted to a higher level than the affinity between the target sequence and the nucleic acid fragment. The nucleic acid fragment according to the present invention is for use in a nucleic acid fragment kit. The nucleic acid fragment of the present invention can be used as a probe for detecting nucleic acid or a competitor for detecting nucleic acid. According to the present invention, human leukocyte antigen (HLA) genes, T-cell receptor genes, red blood cell group determining genes, and Rh antigen genes, and the like can be detected at a high accuracy level. | 12-18-2008 |
20080274213 | Drug for Ameliorating Male Climacteric Disorders - It is intended to provide a highly safe pharmaceutical drug or food that inhibits reduction in blood testosterone level and prevents or ameliorates symptoms and so on associated with male climacteric disorders. The present invention provides a drug for inhibiting reduction in blood testosterone level and a drug for ameliorating male climacteric disorders comprising a plant belonging to the genus | 11-06-2008 |