Entries |
Document | Title | Date |
20080196711 | METHOD AND APPARATUS FOR DELIVERING AN ADDITIVE WITH A CPAP MACHINE - The present invention is a method and apparatus for delivering an additive with a continuous positive airway pressure (“CPAP”) machine. The invention includes mixing an additive with humidifier water and providing the additive to the patient with the CPAP machine. According to certain embodiments, the additive can be an aromatic additive or a therapeutic additive. | 08-21-2008 |
20080210224 | Dose Counter Device for Inhaler - The invention refers to a dose counter device for an inhaler that in a reliable way will register a delivered dose from a canister comprised in the inhaler, and that at the same time substantially will reduce the risk of falsely register a dose not delivered. Thus, the present invention will in an effective way, substantially avoid erroneous counting of delivered doses from the canister. | 09-04-2008 |
20080210225 | DISPOSABLE ANTISTATIC SPACER - A “disposable antistatic spacer” is presented for use as a universal medicinal inhalant applicator offering an inexpensive tube configuration with antibacterial and biodegradable characteristics for efficient administration of pharmaceuticals; including antibiotics, vaccines and brochodilators; having removable parts for adaptability to diverse pressurized inhalant pumps and is furthermore; an interchangeable platform for other pulmonary therapeutic devices. | 09-04-2008 |
20080223361 | Respiratory medicine delivery system - The respiratory medicine delivery system is a handheld breathing device for a user having respiratory problems. The device comprises a hollow tubular manifold. A front tubular section extends from a front opening of the hollow tubular manifold. A mouthpiece extends from a rear opening of the hollow tubular manifold. The front tubular section has an MDI port. A seal cap that can seal off the MDI port is provided. A PEEP valve is mounted in the front tubular section to create a sealed backpressure in the user's airways by creating resistance to exhalation. The hollow tubular manifold has a manifold inlet. A threaded nebulizer port having a recessed one-way valve can be formed at the inlet of the manifold. The nebulizer port is provided for attachment to a nebulizer to facilitate buildup of positive pressure and delivery of medication to a user's lungs. A nebulizer seal cap is also provided. | 09-18-2008 |
20080251068 | Aerosol therapy device - Aerosol therapy device comprising a nebuliser ( | 10-16-2008 |
20080257337 | Ventilator Aerosol Delivery - A method for delivering a medicament to a mechanically ventilated patient receiving a flow of breathing gas comprises delivering a respiratory maneuver to such a patient, monitoring the physiological effects of the respiratory maneuver on such patient, automatically establishing an optimized respiratory maneuver in response to the monitored physiological effects, and delivering the optimized respiratory maneuver to such a patient. A system for delivering an aerosolized medicament to a ventilated patient is also provided. | 10-23-2008 |
20080271732 | Pulmonary Drug Delivery Devices Configured to Control the Size of Administered Droplets - A pulmonary drug delivery device including a drug delivery tube that defines a flow path and a droplet ejection device configured to eject droplets of medication into the flow path. Using collected feedback, the pulmonary drug delivery device can control the size of the droplets that are administered to a user. | 11-06-2008 |
20080283048 | TWO-STAGE REDUCTION OF AEROSOL DROPLET SIZE - A droplet-size reduction system is described. The system in a first embodiment has a catheter having a distal end and a proximal end and a plurality of lumens therein, a chamber at the proximal end of the catheter, the chamber having a first end and a second end and a fluid pathway therebetween, the first end of the chamber being in fluid communication with the plurality of lumens, an aerosol generator between a first one of the plurality of lumens and the first end of the chamber; and a piezoelectric element disposed in the pathway and coupled to an oscillating voltage supply. In another embodiment, the system has a chamber having a first end and a second end and a fluid pathway therebetween, a plurality of catheters in fluid communication with the first end, an aerosol generator between a first one of the plurality of catheters and the first end, and a piezoelectric element disposed in the pathway and coupled to an oscillating voltage supply. In yet another embodiment, the invention is a method of reducing droplet size in a nebulized medicament, by aerosolizing a liquid medicament to create droplets of the medicament, passing the droplets across a piezoelectric element; and delivering the droplets from the piezoelectric element to a patient. | 11-20-2008 |
20080283049 | HIGH EFFICIENCY NEBULIZER - The present invention relates generally to a nebulizer, and more particularly but not exclusively to a compact nebulizer that efficiently utilizes medication. | 11-20-2008 |
20080295826 | Metering System and Method for Aerosol Delivery - An apparatus for metering the delivery of an aerosol. The apparatus has a variable acoustic source and a microphone, both acoustically coupled to a volume having a fluid region and an air region. The apparatus may also include a processor to determine a volume of the air region based on signals received from the microphone and the variable acoustic source. A fluid valve is coupled to the processor, and is configured to allow an amount of fluid to exit the fluid region associated with the volume of the air region. An atomizer, coupled to the fluid region, is configured to aerosolize at least a portion of the fluid. | 12-04-2008 |
20080308095 | Dissociated Discharge EHD Sprayer With Electric Field Shield - The invention is directed to devices and methods for electrohydrodynamic (EHD) aerosolization of liquids utilizing a dissociated discharge electrode and an electric field shield disposed between the nozzle and the discharge electrode. Preferred embodiments are designed as inhalers suitable for administration of therapeutic compounds to the respiratory tract of a patient, preferably the lungs. | 12-18-2008 |
20080308096 | Aerosol Generating Device and Inhalation Therapy Unit Provided with This Device - An aerosol generating device includes a membrane for atomizing a liquid; an actuating device, which is coupled to the membrane so that this membrane is set in oscillatory motion when activated by electric signals; and a flexible substrate, which has electric lines for supplying electric signals to the actuating device and is designed for fastening the aerosol generating device to a fastening area of an inhalation therapy unit, and on which the membrane and the actuating device are held. | 12-18-2008 |
20090020113 | INHALER - An object of the present invention is to enhance the inhalation efficiency by bearing liquid droplets on an air flow at the early stage of inhalation in an inhaler that is used for the user to inhale a medicine ejected from an ejection head. According to one embodiment of the present invention, from an operation in which the user lets out a breath before the start of inhalation, that is, from the exhalation stage, a positive pressure B produced by the exhalation is detected by a pressure detecting unit, and is compared with a standard pattern stored in a storage unit, by which the exhalation profile of the user is prepared. A time difference t between the exhalation finish time and the start time of next inhalation is estimated, followed by the determination of the ejection start time T | 01-22-2009 |
20090050137 | Inhaler With a Mixing Channel for Producing an Aerosol to Be Inhaled - An inhaler with a mixing channel ( | 02-26-2009 |
20090050138 | INHALER - A mouthpiece ( | 02-26-2009 |
20090050139 | LIQUID MEDICINE EJECTION DEVICE - A liquid medicine ejection device for ejecting a liquid medicine as liquid droplets to be inhaled by a user includes means for providing information on the ejection to the user without providing means for determining a state of the ejection when a preliminary ejection operation is carried out, the preliminary ejection operation ejecting an amount of the liquid medicine smaller than an amount ordinarily ejected. The liquid medicine ejection device enables improved reliability of ejection and comfort of a user by carrying out preliminary ejection before inhalation and by making it possible for the user to visually or auditorily check an ejection state of minute liquid droplets with a relatively simple structure to see whether or not the preliminary ejection is carried out correctly. | 02-26-2009 |
20090056708 | DEVICE, SYSTEM AND METHOD FOR TARGETING AEROSOLIZED PARTICLES TO A SPECIFIC AREA OF THE LUNGS - The present invention is directed to the administration of aerosolized particles to specific area of the lungs, and in particular to the targeted delivery of aerosolized pharmaceutical formulations to a specific area of the lungs. More specifically, the present invention relates to devices and methods for depositing aerosolized particles to a specific area of the lungs by regulating aerosolizing parameters of the device. The present invention also relates to devices, systems and methods for disease management, where the aerosolizing parameters are adjusted based on monitoring at least one health parameter. | 03-05-2009 |
20090071469 | Semi-automatic emergency medication dose nebulizer - A conventional respiratory nebulizer has an emergency medication dose storage system conveniently useable in an emergency to deliver the stored medication dose directly to the nebulizing chamber quickly, reliably, and with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication. | 03-19-2009 |
20090095287 | Method and system for vaporization of a substance - The present invention provides an apparatus for the vaporization of materials that releases active constituents for inhalation without the creation of harmful byproducts such as carcinogens associated with combustion and inhalation of substances. The apparatus is designed to fit ergonomically within the user's hand. The apparatus uses the user's inhalation process for air flow. | 04-16-2009 |
20090095288 | DEVICE FOR DELIVERY AND REGULATION OF VOLATILE FLUIDS INTO INSPIRATORY GAS - An apparatus for discharging fluid for a subject breathing. The apparatus includes a fluid cavity for conveying a fluid to be discharged; a valve for guiding the flow of fluid through the fluid cavity; a control unit for controlling the valve for guiding the flow of fluid; a first housing having a wall and a hole on this wall for fluid flowing through the fluid cavity; a first member apart from the first housing having holes discharging fluid through them for the subject breathing; a chamber between the first member and the first housing for receiving the fluid coming along the fluid cavity; a vibrator making the first member to vibrate and discharge fluid through the holes to a subject breathing tube. The vibrator is in contact with the first member through a transmitter extending towards the chamber and which transmitter transmits the vibration effect from the vibrator to the first member. | 04-16-2009 |
20090107491 | Respiratory System for Inducing Therapeutic Hypothermia - The present invention provides a method and apparatus for controlling a patient's body temperature and in particular for inducing therapeutic hypothermia. Various embodiments of the system are described. The system includes: a source of breathing gas, which may be in the form of a compressed breathing gas mixture; a heat exchanger or other heating and/or cooling device; and a breathing interface, such as a breathing mask or tracheal tube. Optionally, the system may include additional features, such as a mechanical respirator, a nebulizer for introducing medication into the breathing gas, a body temperature probe and a feedback controller. The system can use air or a specialized breathing gas mixture, such as He/O | 04-30-2009 |
20090151716 | Semi-automatic emergency medication dose nebulizer - A conventional respiratory nebulizer has an emergency medication dose storage system delivering the stored medication dose directly to the nebulizing chamber with a single impulse of manual force to a simple mechanical delivery system, thereby making the nebulizer useable in two steps: (a) opening the medication capsule with a simple opening action; and (b) inhaling the nebulized medication. The nebulizer can be operated without disassembling the nebulizer housing so as to expose the nebulizing chamber and without manually opening the liquid medication container and, without spillage and without manual pouring of the liquid medication directly into the nebulizing chamber, and without reassembling the nebulizer housing before positioning the inhaler mouthpiece in the mouth so as to inhale the nebulized medication. The delivery system includes a serrated slicing blade to sever the capsule. | 06-18-2009 |
20090188490 | Aerosolizing Inhalation Device - An aerosolizing inhalation device comprising a housing including a battery, a pneumatic switch, an atomizer and a liquid-supplying bottle having a first end connected to the atomizer, wherein the liquid-supplying bottle includes a vent duct, and wherein at least a portion of the housing defines an air orifice. | 07-30-2009 |
20090194099 | Nozzle-System For A Dispenser For Fluids consisting Of A Nozzle And A Nozzle-Holder And/or A Screw Cap - The invention relates to a nozzle system for a delivery device for liquids, which comprises a nozzle and a device which fixes the nozzle in the delivery device. The device has a liquid reservoir from which a liquid is forced through a nozzle under pressure to deliver the liquid. The nozzle is secured by a holder on the delivery device. This holder may itself be secured by a second holder, e.g. in the form of a check nut, or the check nut itself may be the holder. According to the invention at least part of the outer surface of the holding device is micro- or nanostructured. | 08-06-2009 |
20090199848 | Spray Applicator with Positionable Spray Tip - An apparatus for applying a spray to a selected site on a patient includes a sheath having a through bore extending from a first end to a second end. A flexible multi-lumen tube is secured within the sheath and has a distal portion that extends beyond the second end of the sheath. A malleable wire is positioned within at least the distal portion of the multi-lumen tube wherein manual force is exerted upon the distal portion to position the distal end in a selected position by bending the malleable wire. A housing is attached to the rigid outer sheath and has a plurality of ports for engaging a multi-tube syringe and a port for injecting a gas into the selected site wherein each port is in communication with at least one lumen. A spray nozzle is removably attached to the distal end of the multi-lumen tube wherein the at least one liquid and the gas are discharged from the multi-lumen tube and into the spray nozzle such that the aerosol exiting the spray nozzle is effective in treating the selected site. | 08-13-2009 |
20090217923 | Breath-controlled inhalation therapy device - A breath-controlled inhalation therapy device includes an obturation mechanism, obturating a nozzle opening through which a pressurized gas, preferably pressurized air, is issued when the device is in operation. An actuation mechanism actuates the obturation mechanism only in the exhalation phases of the respiration cycle of a patient. The fluid to be atomized is therefore substantially atomized only in the inhalation phases. | 09-03-2009 |
20090217924 | Treatment systems and methods - There is disclosed a system comprising a fluid reservoir, a liquid solution within the reservoir, the solution comprising an antibiotic of the lincomycin family, a spray nozzle, a spray activator, and a tubular connection connecting the spray nozzle and the fluid reservoir. | 09-03-2009 |
20090217925 | METHOD AND APPARATUS FOR DRIVING A TRANSDUCER OF AN INHALATION DEVICE - An inhaler is disclosed wherein medicament in a flat-bottomed container is aerosolized with a vibrator piezoelectric transducer. The transducer is driven by a signal that excites multiple harmonic frequencies to create a complex pattern of oscillations. A circuit for generating the drive signal to the transducer is also disclosed. | 09-03-2009 |
20090235923 | SPRAY DEVICE AND NOZZLE CLOSURE - A spray device including a casing and a spray bottle. A closing element is arranged in a nozzle. The closing element substantially fills the nozzle in order to minimize residual amounts of a drug in the nozzle. The overall purpose is to protect the spray device from contamination and evaporation. A method for manufacturing with as few parts as possible a spray device that by usually manual action causes the spray bottle to effect a pumping movement which triggers a spray dose through the nozzle. The device is intended to increase dose accuracy and facilitate the actual pumping. | 09-24-2009 |
20090235924 | RESERVOIR AND NEBULIZER - A reservoir for a nebulizer, a nebulizer and a method of filling a reservoir are proposed. To avoid undesirable rises in pressure, a fluid chamber of the reservoir is pre-collapsed and filled with an initial amount of fluid which is less than the maximum volume of the fluid chamber. Preferably, before being filled, the fluid chamber is compressed and/or expanded by means of gas to a defined volume which is less than the maximum volume of the fluid chamber. | 09-24-2009 |
20090235925 | AEROSOLISATION SYSTEM - The invention provides a combination of a micro pump | 09-24-2009 |
20090235926 | Multiple Dose Condensation Aerosol Devices and Methods of Forming Condensation Aerosols - Devices and methods of entraining a substance within an airflow are disclosed. Condensation aerosol delivery devices and methods of consistently producing multiple doses of a substance, such as a drug, having high purity, high yield, characterized by a particle size distribution appropriate for pulmonary delivery, and which can be administered to a user in a single dose are also disclosed. | 09-24-2009 |
20090288658 | Antibiotic Formulations, Unit Doses, Kits, and Methods - An aqueous or powder composition includes anti-gram-negative antibiotic or salt thereof being present at an amount ranging from about 100 mg/ml to about 200 mg/ml. Another aqueous or powder composition includes anti-gram-positive antibiotic or salt thereof being present at a concentration ranging from about 0.6 to about 0.9 of the water solubility limit, at 25° C. and 1.0 atmosphere, of the anti-gram-positive antibiotic or salt thereof. Other embodiments include unit doses, kits, and methods. | 11-26-2009 |
20090293868 | Inhalation Therapy Device Comprising an Ampoule for Storing a Medicament To Be Nebulized - An inhalation therapy device includes an atomizer for atomizing a drug which is advantageously present in the form of a fluid into an atomization chamber so that an aerosol or mist is provided in the atomization chamber. The patient or user can inhale the aerosol produced by the atomizer from the atomization chamber via a mouthpiece. The ampoule is inserted into an ampoule holder holding the fluid-containing ampoule. The inhalation therapy device also includes an opening unit for opening the fluid-containing ampoule. The ampoule holder advantageously includes a first part, disposed displaceably in relation to the opening unit, thereby allowing an ampoule present in the ampoule holder to be displaced in the direction of the opening unit. | 12-03-2009 |
20090301471 | EVAPORATION ELEMENT FOR LIQUIDS - An evaporation element for liquids, in particular aqueous solutions, has a first reservoir for storing the liquid that is to be evaporated, a second reservoir, which is separated from the first reservoir by a sheet and contains a reagent that in contact with the liquid that is to be evaporated carries out an exothermic chemical reaction, and an opening element which, on actuation, perforates the sheet and in this way brings the reagent into contact with the liquid that is to be evaporated. | 12-10-2009 |
20090308384 | Apparatus and methods for delivery of medicament to a respiratory system - Apparatus and methods are provided for delivery of a medicament to a respiratory system. A reservoir is provided for a liquid medicament with the reservoir having a liquid medicament inlet port and a medicament outlet. An aerosol generator is provided at the medicament outlet of the reservoir for aerosolizing the liquid medicament. A connector entrains the aerosolized medicament from the aerosol generator with a gas. | 12-17-2009 |
20090314287 | PORTABLE INHALER WITH ADD-ON DEVICE WITH A CHAMBER FOR INTERMEDIATE STORAGE OF AN ATOMIZED MEDICAMENT PREPARATION - An inhaler for propellant-free atomization of a medicament preparation. The inhaler produces an aerosol at low speed. The inhaler is combined with an add-on device for intermediate storage of the aerosol produced, so as to allow easier inhalation, particularly for children. | 12-24-2009 |
20090314288 | PACKAGING AND DELIVERY OF PHARMACEUTICALS AND DRUGS - A blister pack for use with inhalation therapy inhalers comprises an elongate bottom element having an overlying top element defining a plurality of spaced top crowned areas containing powder or liquid medications or drugs. | 12-24-2009 |
20100012114 | PARTICLE-SIZE REDUCTION APPARATUS, AND USE THEREOF - A sterilisable particle-size reduction apparatus, component parts thereof and a method of sterilising and validating sterility thereof are provided. Also provided is use thereof to prepare sterile suspensions of drugs. | 01-21-2010 |
20100051022 | DELIVERY DEVICE AND METHOD - A delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: at least one nosepiece unit ( | 03-04-2010 |
20100071687 | Nebulization Apparatus - A nebulization apparatus includes a nebulization plate, a piezoelectric driving device connected to the nebulization plate for vibrating the nebulization plate, a liquid droplet conveying pipe located below the nebulization plate, a water tank for containing the liquid droplet conveying pipe and an active water supply device connected to the liquid droplet conveying pipe and the water tank. The active water supply device supplies working liquid to the liquid droplet conveying pipe, such that the droplet is attracted by surface tension and attached onto the nebulization plate to form the camber water film to nebulize the working liquid. | 03-25-2010 |
20100083956 | DISCHARGE HEAD AND DROPLET DISCHARGING DEVICE - A discharge head | 04-08-2010 |
20100095957 | Manually operated monodose nasal sprayer device - The nasal sprayer utilizes a piston that fires automatically upon full depression of the firing cap. The drive spring does not fire the piston until fully compressed because the force required to break a puncturable medicine container is greater than to compress the spring. The piston height is greater than the firing cap and central member height combined so that after the spring is fully compressed, the piston punctures the medicine container. The spring then releases, pushing the piston toward the nozzle. A user procures medicine from the device by (i) unlocking a child resistant lock; (ii) applying compressive force against the firing cap to compress the spring and to push the piston to puncture the medicine container, then the spring causes the distal end of the piston to drive medicine through the spray nozzle independent of the user as to dosage amount and speed of delivery. | 04-22-2010 |
20100108058 | POWDER DISPERSION APPARATUS, METHOD OF MAKING AND USING THE APPARATUS, AND COMPONENTS THAT CAN BE USED ON THE APPARATUS AND OTHER DEVICES - Methods and apparatuses for the pulmonary delivery of a composition, such as methods and apparatuses for dispersing dry powder medicaments for inhalation by a patient. Elements or aspects of the apparatuses, including receptacle puncturing mechanisms, deoccluding devices, receptacle impacting devices, and receptacle lock devices or systems. | 05-06-2010 |
20100116268 | AQUEOUS AEROSOL PREPARATIONS CONTAINING THERAPEUTICALLY ACTIVE MICRO-ORGANISMS OR PARTS OF MICRO-ORGANISMS AND METHOD FOR PRODUCING CORRESPONDING AEROSOLS - The invention relates to aqueous aerosol preparations for inhalation, containing therapeutically active micro-organisms or parts of micro-organisms as the active ingredient. | 05-13-2010 |
20100116269 | LIQUID DISCHARGING DEVICE, LIQUID DISCHARGING CARTRIDGE, AND DEVICE BODY CAP - A liquid discharging device includes a device body configured to house a liquid discharging cartridge body having a liquid discharging portion for discharge liquid, and a device body cap removably attached to the device body. When the device body cap is detached from the device body, a discharging portion cap attached to the liquid discharging cartridge body so as to protect a discharging port of the liquid discharging portion is detached from the liquid discharging portion in combination with the device body cap. | 05-13-2010 |
20100139652 | Dispensing Device and Method - Methods and devices for dispensing an aerosolized liquids that generate an electric field proximate an outlet of a liquid supplier to cause liquid issuing from the outlet to be aerosolized for dispensing, and regulating an electrical characteristic, such as voltage, for generating the electric field based on a detected electrical characteristic, e.g., current drawn, of the electric field and/or based on an environmental sensor, to compensate, for example, for adverse effects of relative humidity in the aerosolization process. Such methods and devices are suitable for use as, for example, an inhaler for dispensing therapeutic liquids to a patient's lungs, spraying paint, crops or other liquids over a surface area. | 06-10-2010 |
20100163020 | Method for administering an inhalable compound - A method may include dispensing a dose of an inhalable compound according to a dosing instruction set; and maintaining a hands-free article for dispensing the inhalable compound in an operable dispensing position. | 07-01-2010 |
20100186738 | LIQUID CARTRIDGE - A liquid cartridge of the present invention has a liquid ejection portion | 07-29-2010 |
20100282245 | Detection of nitric oxide - A system for the detection of nitric oxide in a gas sample includes a converter for oxidation of nitric oxide to nitrogen dioxide, a nitrogen dioxide sensor including nanostructures and a filtering device to remove at least carbon dioxide from the gas sample positioned upstream of the converter. The nitrogen dioxide sensor can, for example, include a recognition layer on the nanostructures adapted to enhance sensitivity to nitrogen dioxide. A method for detecting nitric oxide in exhaled breath includes detecting nitric oxide in the exhaled breath using a nitric oxide sensor including nanostructures. Another method for detecting nitric oxide in exhaled breath includes filtering the breath to remove at least carbon dioxide from the breath, oxidizing nitric oxide in the exhaled breath to nitrogen dioxide and detecting the nitrogen dioxide using a nitrogen dioxide sensor including nanostructures. | 11-11-2010 |
20100282246 | NASAL DELIVERY - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece ( | 11-11-2010 |
20100282247 | TREATMENT OF PULMONARY DISORDERS WITH AEROSOLIZED MEDICAMENTS SUCH AS VANCOMYCIN - A method of administering an aerosolized anti-infective, such as a glycopeptide, to the respiratory system of a patient. A ratio of an amount of the glycopeptide, such as vancomycin, delivered to the pulmonary system of the patient in a 24 hour period to a minimum inhibitory amount for the target organ for the same period is about 2 or more. A system to introduce aerosolized medicament to a patient may include a humidifier coupled to an inspiratory limb of a ventilator circuit wye, where the humidifier supplies heated and humidified air to the patient, and an endotracheal tube having a proximal end coupled to a distal end of the ventilator circuit wye. The system may also include a nebulizer coupled to the endotracheal tube, where the nebulizer generates the aerosolized medicament. | 11-11-2010 |
20100288270 | LIQUID EJECTING HEAD - A liquid ejecting head includes an energy generating element for generating energy utilized for ejecting liquid containing a medicine, and a plurality of ejection outlets, provided for said energy generating element, for ejecting the liquid. Each of the ejection outlets has a rotationally asymmetrical cross-section in a plane parallel to the energy generating element. | 11-18-2010 |
20100294268 | Aerosol Generating Method and Device - A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active compound to organs and tissues such as the lung, eye, mucosa and skin. The aerosol is formed through vaporization of the compound while mixing the resulting vapor with a gas, in a ratio, to form the desired particle size when a stable concentration of particles in the gas is reached. | 11-25-2010 |
20100294269 | NEBULIZING DRUG DELIVERY DEVICE WITH AN INCREASED FLOW RATE - The present invention provides a nebulizing drug delivery system for delivering an aerosolized drug to a user having various features to increase the capacity of the drug delivery device. The drug delivery system includes a heater to increase the viscosity of the drug, a double aerosolizing system to double the capacity of the device, and a valve system to continuously replenish drug to the aerosol generator thereby providing a high speed delivery. | 11-25-2010 |
20100300433 | Substrates for Enhancing Purity or Yield of Compounds Forming a Condensation Aerosol - A device for vaporizing a composition. The device comprises a thermally conductive substrate having a surface, the surface comprising a thermally conductive surface structure. A dry composition capable of a solid to liquid phase change upon being heated to at least a select temperature is disposed on the surface structure. The surface structure is configured to form liquid droplets of the composition upon heating of the surface structure to at least the select temperature. The liquid droplets have a median diameter less than a median diameter of liquid droplets formed on a planar substrate surface heated to at least the select temperature. | 12-02-2010 |
20100326431 | Aerosolization Device - In an aerosolization device, an oscillating aerosol generator is installed at a position proximate to an opening at the bottom of a liquid container for aerosolizing a supplied liquid in the container and a sensor is provided to detect an oscillating signal variation according to a condition whether or not the liquid in the container is in contact with the oscillating aerosol generator and the oscillating signal variation is sent to a controller for computation, so as to control whether to continue operating or stop operating the aerosol generator. If the aerosol generator is controlled to stop its operation, the controller will drive an alarm device to send out an alarm signal at the same time. | 12-30-2010 |
20110011392 | OLOPATADINE NASAL SPRAY REGIMEN FOR CHILDREN - A methodology for administering topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose in children is disclosed. Moreover, an ophthalmic product is provided for practicing the methodologies. | 01-20-2011 |
20110023869 | DELIVERY DEVICES - A delivery device for delivering a metered amount of substance (L) in response to exhalation by a user, the delivery device comprising: a mouthpiece ( | 02-03-2011 |
20110030678 | INSUFFLATION SYSTEM - An aerosol generator | 02-10-2011 |
20110030679 | PACKAGING AND DELIVERY OF PHARMACEUTICALS AND DRUGS - A blister pack for use with inhalation therapy inhalers comprises an elongate bottom element having an overlying top element defining a plurality of spaced top crowned areas containing powder or liquid medications or drugs. | 02-10-2011 |
20110041840 | Atomizing Device, Inhaler and Method for Dispensing a Liquid Formulation - An atomizing device ( | 02-24-2011 |
20110079220 | Detection System and Method for Aerosol Delivery - An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to the detector and to the pressure sensor, and is configured to receive at least a signal from the detector and the pressure sensor. The processor is further configured to use the received signals to calculate a volume of the first aerosol, and to output an output signal associated with the calculated volume. The various measurements can be repeated and compared, and the output signal can be a feedback signal for metering subsequent amounts of the aerosol, based on the comparison. | 04-07-2011 |
20110088689 | DEVICE FOR DISPENSING A FLUID PRODUCT - A fluid dispenser device comprising: a body ( | 04-21-2011 |
20110094506 | FLUID PRODUCT DISPENSING DEVICE - A fluid dispenser device comprising: a body ( | 04-28-2011 |
20110108022 | Nebulizer device - An improved tee type nebulizer unit for medicinal use that delivers a mist of properly sized aerosol particles of medicament to the patient. A uniquely configured air flow baffle assembly, which is strategically positioned within the tee of the nebulizer unit, markedly increases the rate of liquid-to-aerosol conversion compared to prior art tee type nebulizer units. More particularly, due to the positioning and sizing of the air channeling pathways within the air flow baffle assembly, an increase in rate of aerosol mist production by factors of 200%-300% is realized. | 05-12-2011 |
20110108023 | AEROSOL GENERATOR - A sonic aerosol generator is provided that provides a constant concentration of particulate aerosol over a long exposure time to an animal. The concentration of aerosols is maintainable for greater than 30 hours at concentrations of 15 mg/m | 05-12-2011 |
20110108024 | Timer for nebulizer compressor - The Timer For Nebulizer Compressor provides a shatterproof plastic casing which houses the unit motor and a piston driven or comparable compressor. Associated accessories such as a mouthpiece, medicine cup and elongated, flexible tubing are also included. The Timer For Nebulizer Compressor runs on standard AC power and can be connected to any power outlet. The novel feature of the Timer For Nebulizer Compressor however, is found in the previously mentioned timer. This timer is directly connected to the unit's shut off valve. As such, a therapist simply prepares the unit for use, at which point the timer is set for the time period required to administer the designated course of treatment. When the treatment was complete and the allotted time had passed, the timer is activated, automatically shutting the nebulizer off and thus preventing the unit from overheating. | 05-12-2011 |
20110114087 | NASAL ADMINISTRATION - A delivery device for and method of providing for delivery of substance to the central nervous system (CNS) of a subject, the delivery device comprising: a nosepiece unit ( | 05-19-2011 |
20110139149 | BOTTLE FOR SINUS CAVITY RINSE - A vessel for use in rinsing a user's nasal cavities includes a main body, a spout, a self-sealing nozzle, and a flow control valve actuable by the user. The spout extends off of the main body and the elastomeric nozzle attached to the spout defines an outer skirt having a deflectable free end upon contact with the walls of the user's nasal cavity. A vacuum breaker valve is formed in a top portion of the main body for actuation by the user to control the flow of a fluid positioned in the vessel out of the nozzle. The main body may include gripping indentations along opposing sidewalls thereof. The spout may be integrally formed with the main body, and the spout and the nozzle may be detachably connected. | 06-16-2011 |
20110139150 | AEROSOL GENERATING MEANS FOR INHALATION THERAPY DEVICES - The invention describes an aerosol generator for inhalation therapy devices, in which an oscillatable assembly, consisting of at least a membrane and an oscillation generator, is mounted in an encapsulating means such that at least the membrane is exposed for the supply of liquid and the generation of an aerosol, whereas the remaining parts of the oscillatable assembly are protected. Mounting occurs by means of a flexible passage such that the oscillatory motions of the oscillatable assembly are not negatively affected. | 06-16-2011 |
20110146670 | NEBULISER FOR VENTILATION MACHINES AND A VENTILATION MACHINE COMPRISING SUCH A NEBULISER - Atomizer for a ventilation machine with a ventilator ( | 06-23-2011 |
20110155128 | NASAL SPRAY AND TISSUE DISPENSER - A spray package including: a container defining a cavity, the cavity having first and second compartments; a spray projection having an orifice in fluid communication with the first compartment; the container having an outlet in communication with the second compartment; a therapeutic liquid disposed in the first compartment and being discharged through the orifice upon application of a force to the container; and one or more tissues disposed in the second compartment, the one or more tissues being removable from the second compartment through the outlet. | 06-30-2011 |
20110168169 | NEBULIZER APPARATUS AND METHOD - A nebulizer for efficiently and reliably delivering aerosolized fluid to an inhaling patient is disclosed. The nebulizer includes a fixed diverter and a movable fluid orifice or fluid pathway connected with an actuator for responding to an inhalation or a manual actuation and beginning the nebulization process. Also provided is a method of providing nebulization including the steps of moving a fluid orifice or fluid pathway connected to an actuator so that the fluid orifice or fluid pathway reaches a nebulizing position during inhalation. | 07-14-2011 |
20110168170 | PRESERVATIVE FREE INSULIN FORMULATIONS AND SYSTEMS AND METHODS FOR AEROSOLIZING - One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation comprises a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation. | 07-14-2011 |
20110180063 | COMPENSATION FOR UNMEASURABLE INSPIRATORY FLOW IN A CRITICAL CARE VENTILATOR - A system and method for operating a ventilator to compensate for external gas flow reaching a patient from an external device, such as a nebulizer. A control unit of the ventilator monitors the gas flow rate from the ventilator and compares the gas flow rate from the ventilator to an expired gas flow rate from the patient. The difference between the inspired flow rate and the expired flow rate is due to the external device. The control unit modifies the operation of the ventilator to compensate for the external gas flow rate such that the flow of gas reaching the patient is maintained at a desired level. | 07-28-2011 |
20110192396 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE - Provided is a pharmaceutical composition for preventing or treating mucus hypersecretion in airways or chronic obstructive pulmonary diseases (COPDs), the pharmaceutical composition including an epidermal growth factor (EGF) and a pharmaceutically acceptable carrier. In addition, a combined preparation capable of respectively administering the pharmaceutical composition and chemotherapeutics is provided. | 08-11-2011 |
20110203580 | AEROSOL DELIVERY SYSTEMS AND METHODS - Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered. | 08-25-2011 |
20110209699 | COMBINATION OF DEHYDROEPIANDROSTERONE OR DEHYDROEPIANDROSTERONE-SULFATE WITH A LIPOXYGENASE INHIBITOR FOR TREATMENT OF ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE - A pharmaceutical or veterinary composition, comprises a first active agent selected from a dehydroepiandrosterone and/or dehydroepiandrosterone-sulfate, or a salt thereof, and a second active agent comprising a lipoxygenase inhibitor for the treatment of asthma, chronic obstructive pulmonary disease, or other respiratory diseases. The composition is provided in various formulations and in the form of a kit. The products of this patent are applied to the prophylaxis and treatment of asthma, chronic obstructive pulmonary disease, or other respiratory diseases. | 09-01-2011 |
20110209700 | INHALATION THERAPY DEVICE COMPRISING A VALVE - The inhalation therapy device according to the invention comprises a nebulizer chamber which accommodates an aerosol generator that emits aerosol into the nebulizer chamber. A valve that has a valve seat, a resilient valve member and a valve member positioning means is arranged at an opening of the nebulizer chamber. The valve member positioning means can be moved out of a first position and into a second position so as to position the valve member on the valve seat in such a manner that in the first position, the valve member, in a flow-free state, is positioned on the valve seat in a pre-tensioned manner and in a second position, is spaced apart from the valve seat. | 09-01-2011 |
20110220101 | GAS MIST INHALER - The present invention is to provide a gas mist inhaler making use of physiological actions of carbon dioxide or oxygen, which is simple in a structure and excellent in effects. The gas mist inhaler is composed of a gas mist inhaler which comprises; a gas supply means | 09-15-2011 |
20110240011 | Treating apparatus - A treating apparatus having a source of a flowable substance, an assembly for releasing the flowable substance in a general direction relative to a target, and a propelling assembly operable to transport the flowable substance from the source to the releasing means whereby the flowable substance is propelled in the general direction relative to the target. | 10-06-2011 |
20110240012 | RECOMBINANT HUMAN CC10 AND COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF NASAL RHINITIS - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of nasal rhinitis, nasal sinusitis, chronic rhinosinusitis, and nasal polyposis. More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10 and intranasal route of administration, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 10-06-2011 |
20110240013 | METHOD OF FORMING AN AEROSOL FOR INHALATION DELIVERY - The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000° C./s, thereby forming a vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. | 10-06-2011 |
20110240014 | SUBSTRATES FOR DRUG DELIVERY DEVICE AND METHODS OF PREPARING AND USE - An assembly and method for producing a condensation aerosol are disclosed. The assembly includes a heat-conductive metal substrate with an oxidation resistant exterior surface and a drug composition film on the exterior surface and is for use in an aerosol device. The thickness of the film and the surface of the substrate is such that the aerosol formed by vaporizing and condensing the drug composition the aerosol contain 10% by weight or less drug-degradation products and at least 50% of the total amount of the drug composition in the film. The methods for treating the exterior surface include heat and chemical treatment and formation of a protective overcoat. | 10-06-2011 |
20110240015 | METHOD AND APPARATUS COMPRISING STEPPED MOUTHPIECE FOR AEROSOL DRUG DELIVERY - The invention of the present application relates to an apparatus to aid in administering inhaled pharmaceutical aerosol to a patient. The apparatus is used in conjunction with an aerosol delivery device. The apparatus comprises steps on the top and bottom of the apparatus, which when used aid the patient causes mandibular advancement, and opening of the mouth, causing opening of patient's airway, resulting in improved aerosol lung deposition. The invention also relates to a method of using such apparatus in a combination with an aerosol delivery device or a system, and to the mouthpiece of said apparatus. | 10-06-2011 |
20110247610 | GAS MIST INHALER - The invention is to provide a gas mist inhaler being simple and excellent in effects by using physiological actions of carbon dioxide or oxygen. The gas mist inhaler has a gas supply means for supplying oxygen, carbon, or a mixed gas (called as “gas” hereafter) of oxygen and carbon dioxide, a gas mist generation means connected to the gas supply means for storing a liquid inside thereof and generating a mist (called as “gas mist” hereafter) prepared by pulverizing and dissolving the stored liquid and the gas, and an inhalation member connected to the gas mist generation means and having an inhalation port of inhaling the gas mist into a living organism, wherein the gas mist inhaler inhales the gas mist into the upper airway and the lower airway of the living organism. | 10-13-2011 |
20110247611 | APPARATUS AND METHOD FOR DELIVERY OF AN AEROSOL - An apparatus for measuring lung ventilation, comprising: a pressure device to measure volume of air flow; an aerosol-generating device that provides aerosol particles to be released at a determined point in a breathing cycle; a mouthpiece with a detector that measures the concentration of aerosol particles for a given volume during the breathing cycle; and a computing device configured to provide lung ventilation data as a function of time constants. | 10-13-2011 |
20110253131 | Apparatus for the administration of pharmaceutical products in aerosol form - An apparatus ( | 10-20-2011 |
20110253132 | Pore Structures for Reduced Pressure Aerosolization - A nozzle comprising a thin, flexible substantially planar polymeric film having a plurality of pores with structures allowing for generation of an aerosol at reduced extrusion pressure is disclosed. The pores can comprise at least two sections, or steps, in which the thickness of the membrane is reduced in stepwise fashion, or the pores can be tapered. Nozzles formed comprising pores having such structures permit aerosol generation at lower extrusion pressures, thereby allowing for decreased weight of aerosolization devices, increased efficiency, increased portability and increased battery life. The pore structures also allow for the use of thicker, more easily processed polymeric films in manufacturing while having a thinner, more efficient aerosolization area. The use of decreased extrusion pressures also results in increased uniformity in aerosol generation and improved reliability of other components. | 10-20-2011 |
20110259323 | ACTUATOR FOR AN INHALER - An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; and an outlet through which a user in use inhales, wherein the outlet has a substantially closed rear section which partitions the outlet from the housing, such that, on inhalation through the outlet, an air flow is drawn substantially only from an outer peripheral surface of the outlet. | 10-27-2011 |
20110259324 | DRIVE UNIT FOR DOSAGE COUNTER - A nebuliser, particularly an MDI, with a counter is proposed. By means of a guide track or inclined plane and an associated guide element, an axial movement occurring on actuation of the nebuliser is partly converted into a rotary movement for driving a counting ring, using an annular rigid drive element with axial teeth. In this way a simple and operationally reliable construction can be achieved, in which even incomplete actuations are counted. | 10-27-2011 |
20110277752 | RECEPTACLE FOR AN AEROSOLIZABLE PHARMACEUTICAL FORMULATION - An article for storing a pharmaceutical formulation. In one or more embodiments, the present invention comprises a receptacle ( | 11-17-2011 |
20110277753 | DISPENSING DEVICE, STORAGE DEVICE AND METHOD FOR DISPENSING A FORMULATION - The invention relates to a dispensing device, a storage device and a method for dispensing a medical formulation. Multiple doses of the formulation are stored in a carrier having multiple storage members, each storage member containing a single dose. Each storage member comprises one duct or nozzle for dispensing the respective dose. The dispensing direction of the ducts or nozzles is directed in a lengthwise or indexing direction of the carrier. The storage device of the carrier is a peelable blister strip, wherein the ducts or nozzles can be opened one after the other by peeling the blister strip. | 11-17-2011 |
20110290239 | NEBULIZER - A nebulizer is proposed which comprises an insertable container and a counter device for counting operations of the nebulizer. The nebulizer can be opened for replacing the container. The counter devices blocks opening of the nebulizer until a predetermined number for operations has been reached. | 12-01-2011 |
20110290240 | METHOD AND DEVICE FOR PERFORMING ORIENTATION DEPENDENT OSCILLATING POSITIVE EXPIRATORY PRESSURE THERAPY - A respiratory device comprising a housing enclosing a chamber and an orientation indicator moveable with respect to the housing between a first position indicative of an orientation of the housing predetermined to be suitable for operation of the respiratory device, and a second position indicative of an orientation of the respiratory device predetermined to be less suitable for operation of the respiratory device. The orientation indicator is positioned in a location on the respiratory device visible to a user during the operation of the respiratory device. | 12-01-2011 |
20110290241 | NEBULIZERS AND FUNCTION UNITS ATTACHABLE TO NEBULIZER - A nebulizer includes a main body unit, an atomization unit, and a breath detection unit, which is a function unit for realizing an additional function of the nebulizer. The main body unit and the atomization unit are separable. The atomization unit includes a storage section for storing the medicinal solution, and an atomizing section for spraying the medicinal solution by atomizing the medicinal solution in the storage section. The main body unit includes a control circuit for performing control to operate the atomizing section. The breath detection unit is attachable between the main body unit and the atomization unit. | 12-01-2011 |
20110297145 | Nasal spray device - A nasal spray device is an environment friendly spray device so as to spray the liquid medicine in the container from the outlet. The nasal spray device includes a push member, a mount, a rod, a block, a resilient member and a cylindrical body. The resilient member made by metal is received in the cylindrical body so that it does not contact the liquid medicine which is prevented from being spoiled. The cylindrical body does not have any bead received therein so as to reduce the number of parts. | 12-08-2011 |
20110297146 | LIQUID EJECTION HEAD TO BE USED FOR INHALER AND INHALER - A liquid ejection head has a plurality of liquid ejection ports | 12-08-2011 |
20110303218 | NASAL NEBULIZER - A nasal delivery system for and a method of delivering aerosolized medication to the nasal passageway of a patient for treating an ailment in the upper respiratory tract above the trachea, comprising: contacting a nosepiece to a patient's nose, the nosepiece being coupled to a directly to the mesh of the vibrating mist nebulizer via a connecting portion, activating the nebulizer to create aerosolized medication from liquid medication in the chamber, directing the aerosolized medication through the connecting portion to the nosepiece; and dispensing, from apertures in the nosepiece, the aerosolized medication directly through the patient's nose. | 12-15-2011 |
20110303219 | GAS BLENDER WITH AUXILIARY MIXED GAS OUTLET - A gas blender with auxiliary mixed gas outlet for mixing a primary gas, generally air, and a secondary gas, generally oxygen, to obtain a mixed gas having several controlled characteristics. The gas blender may be incorporated into a Continuous Positive Airway Pressure (CPAP) device. The gas blender controls the mixing to produce the mixed gas having a predetermined mixture setpoint, generally an oxygen percentage, and a predetermined control setpoint, generally a pressure setpoint or flow rate setpoint. The gas blender provides an auxiliary mixed gas source for use by an auxiliary piece of equipment such as a nebulizer or resuscitation bag. The gas blender includes a primary gas inlet passageway, a secondary gas inlet passageway, a gas mixing apparatus, a mixed gas distribution passageway with an auxiliary mixed gas outlet, a gas sensor, a delivery sensor, a mixed gas delivery control valve, a mixed gas controlled passageway, and a controller. | 12-15-2011 |
20120017892 | USE OF SALT OF AN ACETYLSALICYLIC ACID FOR THE TREATMENT OF VIRAL INFECTIONS - The invention relates to a method of use of a composition comprising a salt of the o-acetylsalicylic acid with a basic amino acid for producing a pharmaceutical composition for the prophylaxis or treatment of viral infections of humans or of animals, in particular mammals and birds. | 01-26-2012 |
20120017893 | METHODS FOR AMELIORATING PAIN AND DEVICES FOR DELIVERING A MEDICAMENT - A method for delivering medicament such as for ameliorating pain in a patient includes introducing an injector through a nasal passage of the patient into a region substantially medial and/or posterior and/or inferior to a sphenopalatine ganglion (SPG) of the patient; and delivering a medicament from the injector superiorly and/or laterally and/or anteriorly towards the SPG. A device for delivering a medicament to a patient in need thereof includes (a) an injector containing a first end configured to remain outside a nasal passage of the patient and a second end configured for entry into the nasal passage of the patient; and (b) an introducer configured for engagement with a nostril of the patient and containing a passageway configured for slidably receiving the injector. The injector is moveable between a storage position preceding the engagement and an engaging position pursuant to the engagement. | 01-26-2012 |
20120042874 | AEROSOL MEDICATION INHALATION SYSTEM - An apparatus for use in conjunction with a metered dose inhaler which includes a novel valve system to aid in the delivery of aerosolized medicament to a subject. The apparatus also includes a novel rotational flow generator to aid in the useable delivery of said medication and avoid its loss either in the apparatus or by non-useful delivery to said subject. | 02-23-2012 |
20120060833 | INHALATION THERAPY DEVICE - The invention relates to an inhalation therapy device having an aerosol generator ( | 03-15-2012 |
20120085343 | NEBULIZER SYSTEMS, APPARATUS AND METHODS FOR RESPIRATORY THERAPY - Nebulizer systems, apparatus, and methods are disclosed. The apparatus includes a body, a breathing gas inlet and outlet, and a barrier. The body is sized to be positioned within an adaptor of the nebulizer system. The breathing gas inlet and the breathing gas outlet are at opposite ends of the body. The barrier is coupled to the body. A plurality of holes are formed in the barrier. The plurality of holes open in a direction orthogonal to the breathing gas inlet. The system employs the apparatus in conjunction with a nebulizer and an adaptor. The method includes generating an aerosolized medicament, providing the aerosolized medicament to the adaptor, passing the aerosolized medicament through the barrier of the apparatus, providing a breathing gas to the apparatus, and flowing the aerosolized medicament and the breathing gas through the breathing gas outlet of the apparatus. | 04-12-2012 |
20120097155 | SYSTEM AND METHOD FOR INTEGRATED PACED BREATHING AND INHALATION THERAPY - The invention provides systems and methods for providing integrated paced breathing and inhalation therapy to a patient. Paced breathing includes alternately providing a high and a low airway pressure to a respiratory system of the patient using a breathing circuit, wherein the high airway pressure coincides with inhalation by the patient and the low airway pressure coincides with exhalation by the patient. A therapeutic substance is delivered to the respiratory system of the patient during the provision of high airway pressure to the respiratory system of the patient, wherein delivery of the compound to the respiratory system of the patient is discontinued during provision of low airway pressure to the respiratory system of the patient. | 04-26-2012 |
20120125325 | THE USE OF AMLEXANOX IN THE THERAPY OF NEUTROPHIL-DRIVEN DISEASES - An agent, which is amlexanox, is useful in the therapy of a disease associated with neutrophilia. | 05-24-2012 |
20120132198 | RESERVOIR AND ATOMIZER - A reservoir and a nebuliser having such a reservoir are proposed. The reservoir comprises a closure for a fluid chamber with a medicament formulation that is formed by two closure members welded together. The closure comprises a particle barrier for preventing the ingress into the fluid chamber of any weld particles that may potentially be formed during the welding of the two closure members. The fluid chamber is preferably broadened in the shape of a beaver tail and is sealed lengthways with an additional strip of material. | 05-31-2012 |
20120138049 | ADAPTER, INHALATION DEVICE, AND ATOMIZER - The invention relates to an adapter ( | 06-07-2012 |
20120167877 | MEMBRANE NEBULIZER AND METHOD FOR WELDING A MEMBRANE TO A CARRIER DURING THE PRODUCTION OF A MEMBRANE NEBULIZER - The invention relates to a membrane nebulizer for producing aerosol in an aerosol therapy device, comprising: a membrane ( | 07-05-2012 |
20120174914 | Electronic vapor inhaling device - An electronic vapor inhaling device has an outer housing that defines an internal cavity having a proximal end and a distal end. A mouthpiece is located at the proximal end. A liquid storage chamber is defined within the outer housing near its proximal end and a battery compartment containing a battery is located near the distal end. An atomizer is positioned between the liquid storage chamber and battery chamber and is in communication with an electronic circuit board. The electronic circuit board is configured to receive input from a unique identifier associated with the electrical resistance of the liquid in the liquid storage chamber and automatically adjust the power supplied to the atomizer. The atomizer rapidly heats the liquid that is injected into an air passageway when the user inhales through the mouthpiece, causing the liquid to vaporize and allow inhalation by the user. | 07-12-2012 |
20120174915 | PULSE DRUG NEBULIZATION SYSTEM, FORMULATIONS THEREFORE, AND METHODS OF USE - Liquid nebulizer apparatus, systems, and formulation compositions, as well as systems for the nebulized, aerosol delivery of such compositions, for the administration and insufflation of medicinal aerosols into the pulmonary system of a mammal are described. The nebulizing apparatus and system can effectively aerosolize a variety of viscosities of medicinal liquid drug carriers, including those made up of oil, water, or emulsions of oil and water. Drugs dissolved or suspended in the compositions and formulations described and adapted for use herein are not damaged or denatured by the nebulization process when the nebulizer described is used. Further, the nebulization system itself can be adapted for use with both mechanically assisted pulmonary ventilation systems as well as hand-held inhalers and nose/mouth face masks for use in pulmonary drug delivery. | 07-12-2012 |
20120186581 | INTEGRATED DELIVERY DEVICE FOR CONTINUOUS GLUCOSE SENSOR - Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction. | 07-26-2012 |
20120199118 | BOTTLE CLOSURE WITH HINGED SEAL - An anesthetic container and closure for transferring anesthesia from a container to a vaporizer. A hinged closure member is moveable between an open position and a closed position by a receiving member of a vaporizer when the anesthetic container is attached to the vaporizer for transfer of liquid anesthetic from the anesthetic container to the vaporizer. The hinged closure member is moved to the closed position upon withdrawal of the receiving member. | 08-09-2012 |
20120211005 | PULMONARY DELIVERY OF ALPHA-1 PROTEINASE INHIBITOR - The present invention relates to a system that includes a pharmaceutical composition of a purified, stable, active alpha-1 proteinase inhibitor (API) in a form of a ready to use sterile solution and an inhalation nebulizer, and to methods of use thereof for treating pulmonary diseases. | 08-23-2012 |
20120216800 | MEDICATION DELIVERY APPARATUS INCLUDING A MEDICATION METERING SYSTEM - A medication delivery apparatus ( | 08-30-2012 |
20120227735 | NEBULIZER FOR A AEROSOLTHERAPY - This invention concerns an ampoule nebulizer per aerosol therapy at different medicament delivery speeds. It comprises a body with a through conduit ( | 09-13-2012 |
20120266870 | DRUG DELIVERY APPARATUS AND METHOD - A nebulizer ( | 10-25-2012 |
20120266871 | SEAL FOR A DISPENSING APPARATUS - The present invention relates to a seal for a valve for use in a pharmaceutical dispensing device, which seal is formed from an elastomeric composition comprising: (a) one or more elastomers; and (b) a cross-linking agent comprising an aliphatic dialkyl peroxide and/or an aliphatic perketal peroxide. | 10-25-2012 |
20120272951 | FORMULATIONS AND METHODS FOR CONTROLLING MDI PARTICLE SIZE DELIVERY - Provided herein are formulations, methods, and metered dose inhaler drug delivery devices. The formulations and methods may provide for controlled particle size delivery in metered dose inhaler drug delivery devices. Further provided are metered dose inhaler drug delivery devices that may themselves deliver controlled sized particles to the airways. | 11-01-2012 |
20120285446 | MAGNETIC COUPLING FOR AEROSOL GENERATING APPARATUS - An apparatus (e.g., nebulizer) for aerosol delivery of a substance (e.g., a drug to a patient) has a mouthpiece ( | 11-15-2012 |
20120291776 | MAGNETIC COUPLING FOR AEROSOL GENERATING APPARATUS - An apparatus (e.g., nebulizer) for aerosol delivery of a substance (e.g., a drug to a patient) has a mouthpiece ( | 11-22-2012 |
20120304983 | NASAL SPRAY - A container for holding and dispensing a liquid and/or dissolved active substance, for example a pharmaceutical or cosmetic active substance, has at least one dispensing organ ( | 12-06-2012 |
20130008436 | RESPIRATORY DRUG DELIVERY APPARATUS INCLUDING A FEEDBACK AND COMPLIANCE DEVICE - A respiratory drug delivery apparatus ( | 01-10-2013 |
20130019860 | METHODS AND COMPOSITIONS FOR THE PREPARATION OF AEROSOLS - The present invention relates to methods for the preparation of an aerosol. More specifically the present invention provides methods for the preparation of an aerosol of immunoglobulin single variable domains wherein the amount of aggregate formation is significantly reduced. The invention further provides aerosols prepared by the methods of the invention, as well as compositions for use in the methods of the invention. The invention further relates to methods for the preparations of such compositions, to containers, kits and aerosol delivery systems comprising such compositions and to uses of the same. | 01-24-2013 |
20130019861 | NEBULIZABLE COMPOSITIONS OF QUATERNARY AMMONIUM MUSCARINIC RECEPTOR ANTAGONISTS - Compositions and methods for treatment, prevention, or amelioration of one or more symptoms of bronchoconstrictive disorders are provided. The compositions provided herein are nebulizable compositions comprising quaternary ammonium muscarinic receptor antagonists. The compositions are suitable for direct administration to a patient in need thereof via a nebulizer. Also provided are kits which comprise of the nebulizable composition of the invention in combination with a nebulizer. Also provided is a method of treating, preventing, or amelioration of one or more symptoms of bronchoconstrictive disorders by administering a therapeutically effective amount of the nebulizable composition of the invention via the use of a nebulizer to a patient in need thereof with minimal to no exposure of the nebulizable composition to the body surface of the patient. | 01-24-2013 |
20130032139 | Drug Condensation Aerosols And Kits - The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation products and are characterized by having an MMAD of between 1-3 microns. These aerosols are made by rapidly heating a substrate coated with a thin film of drug having a thickness of between 0.05 and 20 μm, while passing a gas over the film, to form particles of a desirable particle size for inhalation. Kits comprising a drug and a device for producing a condensation aerosol are also provided, wherein the device, has an element for heating the drug which is coated as a film on the substrate and contains a therapeutically effective dose of a drug when the drug is administered in aerosol form, and an element allowing the vapor to cool to form an aerosol. Methods for use are also disclosed. | 02-07-2013 |
20130074832 | AEROSOL GENERATING MEANS FOR INHALATION THERAPY DEVICES - The invention describes an aerosol generator for inhalation therapy devices, in which an oscillatable assembly, consisting of at least a membrane and an oscillation generator, is mounted in an encapsulating means such that at least the membrane is exposed for the supply of liquid and the generation of an aerosol, whereas the remaining parts of the oscillatable assembly are protected. Mounting occurs by means of a flexible passage such that the oscillatory motions of the oscillatable assembly are not negatively affected. | 03-28-2013 |
20130118484 | Anesthetic Inhalation Aid Device and Attachment Used for the Same - An inhalation mask, an artificial nose unit, an anesthetic gas concentration detector, an extension tube, an anesthesia attachment, and an elastic bag are in communicative connection in sequence. The elastic bag has a mixing chamber formed therein and has an anesthetic inlet, an air inlet, and an outlet port each formed at the boundary to the exterior. The anesthesia attachment includes a hollow structure and an evaporation injector syringe. The outlet port of the elastic bag is in communicative connection with the hollow structure through its opening, and the evaporation injector syringe tightly mates with the interior of another opening. The anesthetic introduced into the mixing chamber is vaporized and then mixed with air introduced from the air inlet into mixed gas. The mixed gas is supplied from the outlet port to the inhalation mask by compressing the elastic bag or other procedures. | 05-16-2013 |
20130125878 | NEBULIZER WITH NEGATIVE PRESSURE STRUCTURE - A nebulizer with a negative pressure structure includes a nebulization body, a carrying cavity, a nebulizing element and a negative pressure generating element. The carrying cavity is provided for carrying a nebulized liquid and has a through hole. The nebulizing element is installed at the through hole and includes a piezoelectric driving unit and a nebulizing plate disposed on a side of the piezoelectric driving unit. The negative pressure generating element is formed on the carrying cavity and provided for changing the volume of the carrying cavity or removing air from the carrying cavity to reduce the air pressure in the carrying cavity, so as to nebulize a liquid of low surface tension or high viscosity effectively. | 05-23-2013 |
20130125879 | MICROPARTICLE FORMULATION FOR PULMONARY DRUG DELIVERY OF ANTI INFECTIVE MOLECULE FOR TREATMENT OF INFECTIOUS DISEASES - The present invention relates to a biodegradable, inhalable microparticle formulation comprising a compound of formula I obtained by fermentation of a microorganism of the | 05-23-2013 |
20130146050 | NASAL SPRAY APPARATUS - A pharmaceutical product in the form of an anti-snoring substance includes a container ( | 06-13-2013 |
20130174838 | DELIVERY SYSTEM FOR THERAPEUTICALLY CONDITIONED AIR - An apparatus for delivery of therapeutically conditioned air to a patient may include a hollow flexible tube and at least one clamp attached to the tube. A shape retention wire may be engaged with the tube. The apparatus may be configured to direct the therapeutically conditioned air to a region near the patient's nose and mouth without being attached to the patient. | 07-11-2013 |
20130192593 | NOZZLE UNIT AND DISPENSER - A nozzle unit for discharge of a pharmaceutical medium and a dispenser equipped therewith. The nozzle unit includes a common supply channel for supply of the medium and first and second discharge nozzles each having a discharge orifice for discharge of the medium supplied through the common supply channel. The nozzle unit is configured for atomized delivery of the medium and includes a first vortex chamber assigned to the first discharge nozzle and a second vortex chamber assigned to the second discharge nozzle for the purpose of atomizing. | 08-01-2013 |
20130220314 | MEDICAL VAPORIZER WITH POROUS VAPORIZATION ELEMENT - An apparatus and method utilize a porous vaporization element with a dispersion mechanism to disperse a liquid agent onto the porous vaporization element. The porous vaporization element extends across a majority of a cross-sectional area of the flow passage. In one implementation, the liquid agent is sprayed onto the porous vaporization element. | 08-29-2013 |
20130233309 | VAPORIZABLE SUBSTANCE DRUG DELIVERY AND MONITORING SYSTEM - This invention relates to a new technology that enables administration of a vaporizable substance to patients for medical purposes. In one embodiment, this invention is a component of a system of technologies, processes and concepts that creates a new method of producing, delivering, administering and regulating the use of medical vaporizable substances. | 09-12-2013 |
20130239956 | AEROSOL GENERATOR - Aerosol generator having a liquid reservoir ( | 09-19-2013 |
20130255670 | System and Method for Performing a Surgical Procedure - In accordance with one embodiment of the present disclosure, a method for performing a surgical procedure may include atomizing at least a portion of a humidification liquid. The method may also include receiving a gas from a source. The method may further include generating a vortex flow of the received gas. The method may further include combining the vortex flow of the received gas with at least a portion of the atomized humidification liquid in order to humidify the received gas. The method may further include providing the humidified gas adjacent to or into a patient. | 10-03-2013 |
20130263845 | HUMIDIFIER SYSTEM FOR HUMIDIFYING GAS DELIVERED TO A PATIENT - Provided are systems and methods for humidifying gas to be provided to a patient utilizing heating of an aerosolized mist. A humidification unit ( | 10-10-2013 |
20130276779 | METHOD OF FORMING AN AEROSOL FOR INHALATION DELIVERY - The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. The method involves: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10μ thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another aspect, a method of forming an aerosol for use in inhalation therapy is provided, wherein the method comprises: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy | 10-24-2013 |
20130284165 | SYSTEM AND METHOD FOR TREATING A MEDICAL CONDITION USING AN AEROSOLIZED SOLUTION - A system for treating a medical condition in a subject using an aerosolized solution includes a subject interface, an inspiratory limb in fluid communication with the subject interface, an expiratory limb in fluid communication with the subject interface, and a controller in electrical communication with the inspiratory and expiratory limbs. The inspiratory limb includes an aerosol-generating device configured to provide the aerosolized solution. The controller is configured to automatically regulate at least one treatment parameter based on feedback from one or more sensors operably integrated into the inspiratory limb and/or the expiratory limb. The at least one treatment parameter is selected from the group consisting of the amount, rate, and temperature of the aerosolized solution. | 10-31-2013 |
20130291859 | NEBULIZER - A nebulizer ( | 11-07-2013 |
20130291860 | Method For Treating Cystic Fibrosis with Inhaled Denufosol - The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, applying about 0.8-3 mL of a solution comprising about 18-65 mg/mL of denufosol into a medication reservoir of an nebulizer to achieve a target loading dose of denufosol of about 25-52 mg denufosol per dosing regimen, nebulizing the solution by passing through holes of an vibrating mesh device equipped with an oscillating membrane in the nebulizer, and delivering an inhaled respiratory dose of 20-33 mg to the lungs of the patient by inhalation within 3-9 minutes. | 11-07-2013 |
20130298902 | ATOMIZER FOR NASAL THERAPY - An atomizing nozzle structured particularly for nasal therapy. Preferred embodiments include a 2-piece atomizing nozzle structured to couple with luer-locking structure carried by a syringe. Such an atomizing nozzle includes a nasal stopper and a stem. A preferred nasal stopper includes a distal tip sized for insertion into a nostril of a human child, with a proximal shield portion being structured to resist over-insertion of a discharge orifice into the nostril. A nasal stopper desirably provides a centering function to urge the discharge orifice away from a nasal wall. One operable stem is structured to couple with the stopper and desirably carries unitary thread structure at a proximal end. A second operable stem is structured as a unitary part of the nasal stopper and also desirably carries unitary thread structure at a proximal end. Certain embodiments may also include spacer structure configured to reduce a dead volume inside the atomizing nozzle. Other embodiments may also include spacer structure configured to reduce dead volume inside a syringe that is coupled to the atomizing nozzle. | 11-14-2013 |
20130298903 | DISPOSABLE THERMAL THERAPEUTIC APPARATUS AND METHOD OF THERMALLY CONTROLLING THE DELIVERY OF MEDICATION THEREWITH - A portable, disposable, thermal drug dispensing apparatus and method of thermally controlling the delivery of medication therewith is provided. The apparatus provides a predetermined thermal energy over a predetermined amount of time to allow effective drug delivery regardless of the external environment. The apparatus produces exothermic or endothermic thermal energy, in a balanced and controlled environment via a chemical reaction between reactants contained as an integral part within the apparatus. The reactants are provided and automatically combined in a selective, predetermined manner within the apparatus to provide the desired thermal cycle needed to produce the desired, thermal environment for effective drug treatment. | 11-14-2013 |
20130298904 | Methods, Devices And Formulations For Targeted Endobronchial Therapy - The present invention provides an improved means of treating tracheobronchitis, bronchiectasis and pneumonia in the nosocomial patient, preferably with aerosolized anti gram-positive and anti-gram negative antibiotics administered in combination or in seriatim in reliably sufficient amounts for therapeutic effect. In one aspect, the invention assures this result when aerosol is delivered into the ventilator circuit. In one embodiment the result is achieved mechanically. In another embodiment, the result is achieved by aerosol formulation. In another aspect, the invention assures the result when aerosol is delivered directly to the airways distal of the ventilator circuit. The treatment means eliminates the dosage variability that ventilator systems engender when aerosols are introduced via the ventilator circuit. The treatment means also concentrates the therapeutic agent specifically at affected sites in the lung such that therapeutic levels of administrated drug are achieved without significant systemic exposure of the patient to the drug. The invention further provides a dose control device to govern this specialized regimen. | 11-14-2013 |
20130306060 | Delivery of Nebulized Medicines - Devices are disclosed that include a positionable elongated member configured to support and delivery tube and maintain a distal end of the tube in a desired position, and to allow the position of the distal end of the tube to be adjusted by a user, and an attachment device configured to allow a proximal end of the elongated member to be secured in a fixed position. These devices may be used, for example, in the delivery of vaporized medicine to a patient, e.g., a child or infant on a bed. | 11-21-2013 |
20130319404 | Liquid Droplet Spray Device - A liquid droplet spray device for ejecting a liquid as a spray of droplets has a cartridge ( | 12-05-2013 |
20130327320 | DELIVERY DEVICE AND METHOD - A delivery device for and method of delivering substance, in particular a vaccine, to a mucosal surface within the oral cavity of a subject, the device comprising: a mouthpiece unit to be gripped in the mouth of a subject, wherein the mouthpiece unit is configured such that, on exhalation or attempted exhalation by the subject, a pressure is developed in the oral cavity which is such as to close the oropharyngeal velum of the subject; and an oral outlet unit including at least one outlet from which substance is in use delivered to a mucosal surface within the oral cavity of the subject. | 12-12-2013 |
20130327321 | SUBLINGUAL FENTANYL SPRAY - The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable salt thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations. | 12-12-2013 |
20130333695 | METHOD AND SYSTEM FOR THE ADMINISTRATION OF A PULMONARY SURFACTANT BY ATOMIZATION - A method and system according to preferred embodiments of the present invention allows optimizing the dispensing of aerosol medicaments. In particular the system according to a preferred embodiment of the present invention allows the administration of an exogenous pulmonary surfactant to very young patients (e.g. preterm neonates). A catheter | 12-19-2013 |
20140000587 | LATERALLY-ACTUATED FLUID PRODUCT DISPENSING DEVICE | 01-02-2014 |
20140000588 | LATERALLY-ACTUATED FLUID PRODUCT DISPENSING DEVICE | 01-02-2014 |
20140007864 | SYSTEMS AND METHODS FOR DRIVING NEBULIZERS - In various arrangements, a nebulizer element of a nebulizer may be energized with a drive signal. A phase offset of the drive signal may be measured. A phase delta may be determined. The phase delta may indicate a difference between a target phase offset and the measured phase offset. The target phase offset may indicate a non-zero target phase difference between the voltage of the drive signal and the current of the drive signal. A frequency of the drive signal may be changed to decrease the phase delta. | 01-09-2014 |
20140007865 | OLOPATADINE NASAL SPRAY REGIMEN FOR CHILDREN - A methodology for administering topical formulations of olopatadine for treatment of allergic or inflammatory disorders of the nose in children is disclosed. Moreover, an ophthalmic product is provided for practicing the methodologies. | 01-09-2014 |
20140014093 | COMPENSATION FOR UNMEASURABLE INSPIRATORY FLOW IN A CRITICAL CARE VENTILATOR - A system and method for operating a ventilator to compensate for external gas flow reaching a patient from an external device, such as a nebulizer. A control unit of the ventilator monitors the gas flow rate from the ventilator and compares the gas flow rate from the ventilator to an expired gas flow rate from the patient. The difference between the inspired flow rate and the expired flow rate is due to the external device. The control unit modifies the operation of the ventilator to compensate for the external gas flow rate such that the flow of gas reaching the patient is maintained at a desired level. | 01-16-2014 |
20140014094 | AEROSOLIZED THERAPY KIT - A comprehensive aerosol therapy for administration to a patient in need of treatment is provided. More particularly, the aerosol therapy kit provides a seamless conduit for a patient to receive in-office or hospital inhalation treatments and access to drugs and equipment for continuing home use. | 01-16-2014 |
20140041652 | NANO-AEROSOL GENERATION SYSTEM AND METHODS - The invention provides methods and apparatus for stable generation and delivery of solid nano-particles in aerosols that simultaneously maintain high nano-particle concentration, and which avoid coagulation and agglomeration of the nano-particles. The apparatus includes a Collison nebulizer is in communication with a plenum. The Collison nebulizer includes a port for introducing a helium gas flow into the Collison nebulizer. The plenum includes component(s) for providing flow of uniform axially symmetrical dry air around the nano-particles entrained in the helium gas flow in the plenum. Preferably, the plenum includes an uniformity screen and a reduction in the plenum circumference downstream from the uniformity screen. In some preferred aspects, the invention provides methods of introducing nanoparticles into the lungs of test animals. The present invention allows more than 0.5 mass % of the nano-particles to be deposited in an animal's lungs. | 02-13-2014 |
20140041653 | PRESERVATIVE-FREE SINGLE DOSE INHALER SYSTEMS - An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane. | 02-13-2014 |
20140041654 | METHOD FOR TREATMENT OF LUNG INFECTIONS BY ADMINISTRATION OF AMINOGLYCOSIDES BY AEROLISATION - The present invention regards a novel administration form and a novel administration regime useful in the treatment and prevention of a bacterial lung infection in patient in need thereof, in particular by providing a composition useful for aerosolization of a highly concentrated solution of aminoglycosides such as Tobramycin. | 02-13-2014 |
20140048061 | SYSTEM AND METHOD FOR ADMINISTERING ANESTHETICS WHILE PERFORMING CPR - According to one embodiment, a device for delivering an anesthetic to an individual to reduce reperfusion injury during the performance of cardiopulmonary resuscitation (CPR) is provided. The device includes a patient connection mechanism for coupling with an airway of the individual and an anesthetic delivery mechanism for receiving the anesthetic and for delivering the anesthetic to the individual via the patient connection mechanism. In some embodiments, the anesthetic is delivered with the assistance of an intrathoracic pressure regulation (IPR) mechanism or an impedance threshold device (ITD) coupled with the patient connection mechanism. The IPR mechanism may be configured to change a pressure in the airway and a thorax of the individual via application of a vacuum source. The ITD device may be configured to prevent respiratory gases from entering the lungs for at least some time during a decompression or relaxation phase of CPR. | 02-20-2014 |
20140053830 | Methods, Devices And Formulations For Targeted Endobronchial Therapy - The present invention provides an improved means of treating tracheobronchitis, bronchiectasis and pneumonia in the nosocomial patient, preferably with aerosolized anti gram-positive and anti-gram negative antibiotics administered in combination or in seriatim in reliably sufficient amounts for therapeutic effect. In one aspect, the invention assures this result when aerosol is delivered into the ventilator circuit. In one embodiment the result is achieved mechanically. In another embodiment, the result is achieved by aerosol formulation. In another aspect, the invention assures the result when aerosol is delivered directly to the airways distal of the ventilator circuit. The treatment means eliminates the dosage variability that ventilator systems engender when aerosols are introduced via the ventilator circuit. The treatment means also concentrates the therapeutic agent specifically at affected sites in the lung such that therapeutic levels of administrated drug are achieved without significant systemic exposure of the patient to the drug. The invention further provides a dose control device to govern this specialized regimen. | 02-27-2014 |
20140060523 | DISCHARGE DEVICE FOR A FLOWABLE SUBSTANCE - A discharge device for a flowable substance is proposed, comprising at least one storage element ( | 03-06-2014 |
20140060524 | ATOMIZING DEVICE AND ELECTRONIC CIGARETTE USING THE SAME - The present invention provides an atomizing device and an electronic cigarette using the same. The atomizing device includes an outer sleeve, a liquid storage layer, a heating assembly, an atomizing elastic seat and a hard connecting assembly. The hard connecting assembly is inserted in the atomizing seat to elastically squeeze and tensioningly engage. The atomizing seat is adapted for the outer sleeve, and elastically expanded as a result of the connecting assembly being inserted in the elastic atomizing seat to be tightly sealed in the inner wall of the outer sleeve. The electronic lines are respectively tensioningly fixed in the elastic atomizing seat and electrically connect to the connecting assembly. The strength of the atomizing device is highly enhanced and assures further assembly. The atomizing seats is squeezed and sealed by the connecting head, of which sealing is better and avoid too soft of the simply using silicon glue. | 03-06-2014 |
20140060525 | Drug Condensation Aerosols And Kits - The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation products and are characterized by having an MMAD of between 1-3 microns. These aerosols are made by rapidly heating a substrate coated with a thin film of drug having a thickness of between 0.05 and 20 μm, while passing a gas over the film, to form particles of a desirable particle size for inhalation. Kits comprising a drug and a device for producing a condensation aerosol are also provided. The device contained in the kit typically, has an element for heating the drug which is coated as a film on the substrate and contains a therapeutically effective dose of a drug when the drug is administered in aerosol form, and an element allowing the vapor to cool to form an aerosol. Also disclosed, are methods for using these aerosols and kits. | 03-06-2014 |
20140069419 | ISOXAZOLIDINE DERIVATIVES - Glucocorticosteroids that are derivatives of isoxazolidine are useful as anti-inflammatory and antiallergic compounds of the glucocorticosteroid series. | 03-13-2014 |
20140076308 | NOZZLE AND INHALER AND METHOD FOR PRODUCING A NOZZLE - A nozzle, an inhaler with a nozzle and a method for producing a nozzle are proposed. The nozzle comprises two holes formed in a flat plate. Then, the plate is deformed such that the axes of the holes intersect so that jets of fluids generated by the holes impinge with each other. | 03-20-2014 |
20140096765 | INHALED HYPERTONIC SALINE DELIVERED BY A HEATED NASAL CANNULA - The invention described herein is directed to method of treating chronic obstructive pulmonary disease, comprising administering an effective amount of an osmolyte by at least one nasal cannula to a subject in need thereof. Also provided is a nasal cannula system for delivering an osmolyte, comprising a nebulizer and tubing having two ends, where the first end of the tubing is connected to the nebulizer and the second end of the tubing is tapered to fit in the nostril of a subject. | 04-10-2014 |
20140109898 | ATOMIZING DEVICE AND ELECTRONIC CIGARETTE HAVING SAME - An atomizing device of an electronic cigarette is provided. The atomizing device includes a screw sleeve and an electrode ring fixed in the screw sleeve. The screw sleeve includes a glass fiber core, a heating coil winding around the glass fiber core and a heating coil support. Each of two ends of the heating coil is respectively connected to a silver coated bare electrical wire. The heating coil support has a central through hole and two side wall through holes. The bare electrical wires respectively extend through the side wall through holes which are exposed to two ends of the heating coil support, then respectively in contact with the screw sleeve and the electrode ring. An electronic cigarette having the atomizing device is also disclosed. | 04-24-2014 |
20140116426 | INHALATION DEVICE FOR USE IN AEROSOL THERAPY - The invention provides an inhalation device comprising a base unit, a mouthpiece, and an aerosol head. The base unit comprises an air inlet, an air outlet opening, a groove for receiving the mouthpiece, and key lock member(s). The mouthpiece comprises a first segment, comprising an air inlet opening and a lateral opening for receiving an aerosol generator, the first segment being insertable into the groove of the base unit, and a second segment comprising an aerosol outlet. The aerosol head comprises an aerosol generator, a liquid reservoir, and key lock member(s) complementary to the key lock member(s) of the base unit. The base unit, mouthpiece and aerosol head are connectable with one another such that when engaging the members of the key lock with the complementary members, the aerosol generator is inserted into the lateral opening of the mouthpiece. | 05-01-2014 |
20140144429 | METHODS AND DEVICES FOR COMPOUND DELIVERY - Provided herein are methods, devices, systems, and computer readable medium for delivering one or more compounds to a subject. Also described herein are methods, devices, systems, and computer readable medium for transitioning a smoker to an electronic nicotine delivery device and for smoking or nicotine cessation. | 05-29-2014 |
20140158116 | INHIBITING TRPA1 FOR THE TREATMENT OF ASTHMA - This disclosure describes novel compounds and pharmaceutical compositions for inhibiting the TRPA1 ion channel and/or medical conditions related to TRPA1, such as asthma. | 06-12-2014 |
20140158117 | Compositions Comprising Azelastine and Methods of Use Thereof - The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions, into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent. The invention also provides methods of treating or preventing certain disorders, or symptomatic relief therefrom, by administering the compositions of the invention to a patient, e.g., for the symptomatic relief of allergic rhinitis, non-allergic vasomotor rhinitis, allergic conjunctivitis, as well as other disorders. | 06-12-2014 |
20140165998 | INDICATING DEVICE WITH WARNING DOSAGE INDICATOR - An indicating device for indicating the number of dosages of a substance that have been dispensed from or remain in a container includes a first housing member having laterally spaced apart first and second guide members and a second housing member. The first and second housing members are moveable relative to each other along a longitudinal axis. The second housing member includes laterally spaced apart first and second guides shaped to receive the first and second guide members respectively, and wherein the first and second guides are not shaped to receive the second and first guide members respectively. A biasing member biases the second member relative to the first member along the longitudinal axis. An indicating member is disposed between the first and second housing members. | 06-19-2014 |
20140165999 | CAPILLARY SYSTEM WITH FLUIDIC ELEMENT - An aerosol generation system having an aerosol generator wherein a liquid formulation is at least partially volatilized in a capillary passage and discharged from the capillary passage to form an aerosol. The aerosol generation system includes a pumping unit adapted to supply a liquid formulation to the aerosol generator; and a fluidic element located between the pumping unit and the capillary passage of the aerosol generator, wherein the fluidic element increases backpressure of the liquid formulation as the liquid formulation enters the capillary passage of the aerosol generator. | 06-19-2014 |
20140202453 | PROCESS FOR MANUFACTURING AN INTEGRATED MEMBRANE OF NOZZLES IN MEMS TECHNOLOGY FOR A SPRAY DEVICE AND SPRAY DEVICE USING SUCH MEMBRANE - A process for manufacturing a membrane of nozzles of a spray device, comprising the steps of laying a substrate, forming a membrane layer on the substrate, forming a plurality of nozzles in the membrane layer, forming a plurality of supply channels in the substrate, each supply channel being substantially aligned in a vertical direction to a respective nozzle of the plurality of nozzles and in direct communication with the respective nozzle. | 07-24-2014 |
20140202454 | INHALER COMPONENT - The invention relates to an inhaler component for forming a vapour/air mixture or/and condensation aerosol by evaporation of a liquid material ( | 07-24-2014 |
20140202455 | METHOD AND APPARATUS FOR CONTROLLING A VENTILATION THERAPY DEVICE - A method and apparatus provide closed-loop control of the operation of a ventilator device based on physiological parameters received from and/or through a patient monitor device, which is a separate and discrete device from the ventilator device. | 07-24-2014 |
20140209094 | Detection System and Method for Aerosol Delivery - An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to the detector and to the pressure sensor, and is configured to receive at least a signal from the detector and the pressure sensor. The processor is further configured to use the received signals to calculate a volume of the first aerosol, and to output an output signal associated with the calculated volume. The various measurements can be repeated and compared, and the output signal can be a feedback signal for metering subsequent amounts of the aerosol, based on the comparison. | 07-31-2014 |
20140230811 | MOUTHPIECE AND METHOD FOR DELIVERING NEBULIZED MEDICAMENT TO THE AIRWAY OF A SUBJECT - A mouthpiece ( | 08-21-2014 |
20140251319 | THERMAL MATERIAL NEBULIZING SYSTEM - A system for thermal regulation of a nebulizer is provided. The system includes a container to house a nebulizer and a thermal material together. The thermal material acts to chill a liquid located inside the nebulizer, in order to deliver a chilled mist to a patient for therapeutic purposes, such as initiating. Therapeutic Hypothermia, or treating various respiratory illnesses such as croup, laryngobronchitis, and smoke inhalation. | 09-11-2014 |
20140290646 | THERAPY APPLIANCE - A therapy appliance, in particular for use for administering medicaments by nasal inhalation, includes a ventilation tube, on the input side of which is attached an aerosol generator connected to a medicament container, which aerosol generator is connected to a control unit. The ventilation tube is attached at the end to a nasal applicator. | 10-02-2014 |
20140290647 | INTRANASAL ADMINISTRATION OF AGENTS WITH PRO-INFLAMMATORY ACTIVITY FOR THE THERAPY OF NEUROLOGICAL DISORDERS - The invention concerns a product consisting of distilled water or of an aqueous solution hypotonic or substantially isotonic with respect to blood plasma or, less preferably, hypertonic with respect to blood plasma, to be administered on the nasal mucosa according to a specific operation mode in order to cause an inflammation of an irritative kind, for use in a treatment of stimulation of the endogenous production of inflammatory mediators, in the therapy and prevention of neurological disorders, in particular of degenerative disorders of the central and peripheral nervous system. The inflammatory mediators the endogenous production of which is stimulated comprise NGF, neurotrophin-3, neurotrophin-4, serotonin, substance P, heparin, ECF-A. | 10-02-2014 |
20140318533 | LIQUID DISPENSING AND METHODS FOR DISPENSING LIQUIDS - A dispenser for supplying a metered volume of a liquid medicament to an aerosolizing device. The dispenser may include a container having a proximal end and a distal end, wherein the container is configured to store a volume of liquid medicament. The dispenser may also include a dispensing mechanism coupled to the distal end of the container. The dispensing mechanism may have a distal end terminating in a tip through which the liquid medicament is dispensed. The dispensing mechanism operates to dispense a metered volume of the liquid medicament from the tip each time the dispensing mechanism is operated. The distal end of the dispensing mechanism includes an interface that interacts with a housing of an inhaler to limit an insertion depth of the tip into an opening the housing. | 10-30-2014 |
20140331994 | SYSTEM COMPRISING A NEBULIZER AND A PACKAGING - A system comprising a nebulizer, in particular inhaler, having a pre-installed container is proposed. The system comprises a packaging preventing fluidic connection or opening of the container in a delivery state of the nebulizer. | 11-13-2014 |
20140366871 | ATOMIZER - An atomizer for the delivery, and in particular, for the atomization of a formulation, particularly, a powder has a simple construction that makes a simple intuitive operation possible. In particular, such is achieved by the fact that the atomizer has a mouthpiece with an associated cover, so that opening and/or closing of the cover causes a delivery medium, in particular air, to be taken in and/or put under pressure by a delivery device, a spring store is put under tension and/or a preferably annular reservoir containing a plurality of doses of the formulation is further rotated. | 12-18-2014 |
20140366872 | AEROSOLS FOR SINUNASAL DRUG DELIVERY - A pharmaceutical aerosol is disclosed which is suitable for delivering an active compound to the mucosa of the nose, the osteomeatal complex or a paranasal sinus. The pressure of the aerosol is not constant, but pulsates at a frequency from about 10 to 90 Hz. The aerosol is further characterised in that it exhibits a low effective flow rate of less than about 5 litres per minute. The aerosol is, inter alia, suitable for the prevention, management, or treatment of a disease, symptom, or condition affecting the nose or the paranasal sinuses, such as acute and chronic sinusitis. | 12-18-2014 |
20150007810 | Delivery of Nebulized Medicines - Devices are disclosed that include a positionable elongated member configured to support a delivery tube and maintain a distal end of the tube in a desired position and directional orientation, and to allow the position and orientation of the distal end of the tube to be adjusted by a user. The devices include a multi-segment elongated member configured to support a delivery tube and maintain a distal end of the tube in a desired position and orientation, and a multi-axis joint assembly disposed between segments of the elongated member to allow articulated relative movement of the segments. These devices may be used, for example, in the delivery of vaporized medicine to a patient, e.g., a child or infant on a bed. | 01-08-2015 |
20150027440 | AEROSOL DELIVERY DEVICE AND METHOD FOR OPERATING AN AEROSOL DELIVERY DEVICE - The invention relates to an aerosol delivery device ( | 01-29-2015 |
20150034075 | AEROSOL GENERATING MEANS FOR INHALATION THERAPY DEVICES - The invention describes an aerosol generator for inhalation therapy devices, in which an oscillatable assembly, consisting of at least a membrane and an oscillation generator, is mounted in an encapsulating means such that at least the membrane is exposed for the supply of liquid and the generation of an aerosol, whereas the remaining parts of the oscillatable assembly are protected. Mounting occurs by means of a flexible passage such that the oscillatory motions of the oscillatable assembly are not negatively affected. | 02-05-2015 |
20150040890 | NEBULIZER - A nebulizer and a housing part comprising a blocking device as well as use of a blocking device are proposed. The blocking device blocks a rotatable element of a counter device in a defined rotational position until the nebulizer is closed. | 02-12-2015 |
20150047631 | Medicament Delivery Device - A medicament delivery device for a disposable container having at least one chamber for a liquid medicament encapsulated in the container by at least one movable plunger. The medicament delivery device is elongated along a longitudinal axis (A), has proximal and distal ends, and includes a housing with proximal housing section configured for accommodating the disposable container and a distal housing section; a plunger rod configured for contacting the movable plunger; and a drive mechanism arranged in the distal housing section for applying, when the medicament delivery device is activated, a force on the movable plunger in a proximal direction via the plunger rod. The plunger rod includes an outer periphery having at least two axially separated recesses or cut-out portions for retaining liquid medicament that leaks along the plunger rod toward the drive mechanism. | 02-19-2015 |
20150075520 | METERED QUANTITY SYRINGE- TYPE DISPENSER - Provided is a metered quantity syringe-type dispenser that is capable of multistage pushing. The metered quantity syringe-type dispenser includes a syringe; a plunger configured to be pushed into the syringe; an elastic deforming portion configured to be deformed in response to the pushing of the plunger; and a stopper portion configured to be locked with respect to the syringe and to be released from the locking by restoring force of the elastic deforming portion. | 03-19-2015 |
20150090253 | VAPORIZATION DEVICE AND METHOD OF PREPARATION AND USE - A vaporization device and its method of use, where the device can accommodate a plurality of formulations for dispensing by selecting the desired source. Such formulations can include different drug formulations for providing different effects on the user. Also, an indicator with specialized indicia can be provided to identify the source being dispensed. | 04-02-2015 |
20150101595 | Controllable Rate Turbulating Nozzle - A piercing device for use in internally pierced blister delivery devices include a base, a piercer body and an internal fluid path. The internal fluid path includes one or more inlet channels into a central cavity which is connected to one or more delivery channels and exit ports. The cavity is defined by angular walls and top to create turbulence in the fluid flow and to produce a controllable spray, mist, drops, plume or stream delivery. The piercer body also provides a pointed lancet disposed in the center of the exit ports for piercing the lidstock of a formed blister. | 04-16-2015 |
20150122247 | NEBULISER WITH CODING MEANS - A nebuliser and a housing part removably connected thereto, each having a coding, are proposed. To increase the flexibility in the coding while using carry-over parts at least one of the coding means can be mounted in different defined positions on the nebuliser or the housing part removably connected thereto so that in each position a different coding is obtained in which the coding means match one another. | 05-07-2015 |
20150122248 | AEROSOL DELIVERY SYSTEM - A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well. | 05-07-2015 |
20150128934 | WOUND TREATMENT AND CLEANING SYSTEM AND METHOD - A wound treatment/cleaning device is described as having a sprayer portion and a brush portion each designed to be used with standard sized fluid bottles. The sprayer and brush can be packed with and/or sterilized with the fluid bottles, or packaged/sterilized separately. When the sprayer and brush are used in conjunction with the fluid bottle, the sprayer allows the fluid to be sprayed directly onto the wound to numb the wound while the brush can be used to clean the wound after it has been numbed. | 05-14-2015 |
20150128935 | INHALATION SYSTEMS, BREATHING APPARATUSES, AND METHODS - Examples of the invention include inhalation systems, breathing apparatuses, and methods for administering a solution by inhalation to a patient. Example breathing apparatuses described herein may be configured to minimize loss of the solution to the environment. Additionally or instead, example breathing apparatuses may be configured to recirculate exhaled solution to increase an amount of the solution available to a patient while minimizing exhausted solution. In some examples, breathing apparatuses may deliver nebulized platelet rich plasma (“PRP”). | 05-14-2015 |
20150144127 | VALVED CONTAINER ASSEMBLY - A valved container assembly ( | 05-28-2015 |
20150290418 | TREATMENT OF RESPIRATORY CONDITION USING TARGETED DELIVERY - System and methods are provided for targeted delivery of agent for treatment of a respiratory condition. A respiratory characteristic is measured, and an agent is delivered based on the respiratory characteristic during a respiratory cycle. A computer controlled system is used to control mixing of an agent into the fluid delivery channel of a ventilator to treat the respiratory condition of a patient. | 10-15-2015 |
20150297846 | INTRANASAL MEDICATION DELIVERY DEVICE AND METHOD OF USE THEREOF - The intranasal medication delivery device and method of use thereof includes an elongated malleable member arcuately curved or pre-formed in manner complimentary to the anterior wall of a nasal cavity. One particular embodiment provides the elongated and arcuate member to deliver medication through a lumen such that the medication is deposited in a semi-solid state adjacent the anterior aspect of the nasal cavity lateral wall and to the anterior end of the superior, middle, and inferior turbinate. Another particular embodiment provides the elongated and arcuate member to deliver medication as a suppository to a location similar to that of the previous embodiment. The method of delivering the medicine provides depositing the medicine adjacent the anterior end of one of the superior turbinate, middle turbinate, and inferior turbinate. An exemplary medication can be any one of a corticosteroid, an anti-histamine, an immune active mediator, an IgE binding medication, or a decongestant. | 10-22-2015 |
20150313842 | UNIT DOSES, AEROSOLS, KITS, AND METHODS FOR TREATING HEART CONDITIONS BY PULMONARY ADMINISTRATION - Methods of treating atrial arrhythmia include administering an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof, such that the at least one antiarrhythmic pharmaceutical agent first enters the heart through the pulmonary vein to the left atrium. Other methods of treating atrial arrhythmia include administering by inhalation an effective amount of at least one antiarrhythmic pharmaceutical agent to a patient in need thereof. An amount of the at least one antiarrhythmic pharmaceutical agent may peak in the coronary sinus of the heart at a time ranging from 10 seconds to 30 minutes from initiation of the administering. Unit doses, aerosols, and kits are also contemplated. | 11-05-2015 |
20150314085 | VAPOR MEDICINE DISPENSING AND NANO-MIST LUNG CLEANSER SYSTEM - A system, accompanying apparatuses and methods relating to an oral, nasal or propellant enhanced mist delivery, drug delivery and lung cleansing apparatuses and having for an object to provide a safe and harmless means for and method of delivering medication with heated, moist, flavored air; or by inhaling warm medication like methanol into the lungs in case of a respiratory ailment under direction of a physician. Additionally, all state of the art medicines are envisioned for delivery with the system. | 11-05-2015 |
20150320947 | NEBULIZER - A nebulizer and a container with a fluid for such a nebulizer are described, the container comprising an indicator device fixedly mounted on the bottom of the container, the indicator device stopping further use of the container in a locked state when a predetermined number of uses has been reached or exceeded, and when the nebulizer is partially opened, it is blocked against further use, and after replacement of the container including the indicator device, the nebulizer can be used again. | 11-12-2015 |
20150328414 | INHALATION THERAPY DEVICE COMPRISING A VALVE - The inhalation therapy device according to the invention comprises a nebulizer chamber which accommodates an aerosol generator that emits aerosol into the nebulizer chamber. A valve that has a valve seat, a resilient valve member and a valve member positioning means is arranged at an opening of the nebulizer chamber. The valve member positioning means can be moved out of a first position and into a second position so as to position the valve member on the valve seat in such a manner that in the first position, the valve member, in a flow-free state, is positioned on the valve seat in a pre-tensioned manner and in a second position, is spaced apart from the valve seat. | 11-19-2015 |
20150335575 | PHARMACEUTICAL SPRAY COMPOSITION COMPRISING A VITAMIN D ANALOGUE AND A CORTICOSTEROID - The present invention relates to a topical spray composition comprising a biologically active vitamin D derivative or analogue and a corticosteroid, and its use in the treatment of dermal diseases and conditions. | 11-26-2015 |
20150343164 | Automated HME with Nebulizer Connection - An airway circuit has two modes of operation, dependent upon the presence or absence of a nebulizer in a nebulizer port. When the nebulizer if absent, a patient port is in fluid communications with a ventilation circuit port through a heat and humidity exchange element. When the nebulizer is inserted into the nebulizer port, the nebulizer port (and nebulizer), patient port, and ventilation circuit port are in fluid communications with each other and the heat and humidity exchange element is isolated, thereby protecting the heat and humidity exchange element from medicines emanating from the nebulizer. After the nebulizer is removed from the nebulizer port, the patient port is again placed in fluid communications with the ventilation circuit port through a heat and humidity exchange element. | 12-03-2015 |
20150352297 | LIQUID DRUG CARTRIDGES AND ASSOCIATED DISPENSER - Liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a container for storing the liquid drug, an end cap having an ejection opening, a filter element, and a piston that is repositionable relative to the container to selectively eject a volume of liquid drug from the ejection opening. The filter element filters the liquid drug prior to ejection from the ejection opening. The liquid drug cartridge can be coupled with an inhaler that includes an aerosol generator. The aerosol generator includes a vibratable membrane onto which the liquid drug is ejected. The liquid drug is aerosolized by the vibration of the membrane for inhalation by a user. | 12-10-2015 |
20150352298 | Medicament Delivery Device - A medicament delivery device for delivering metered doses of medicament, wherein an indicator mechanism ( | 12-10-2015 |
20150359978 | Medicament Delivery Device - A metered droplet medicament delivery device for delivering metered doses of medicament includes a proximal part and a distal part having opposite distal and proximal ends; a medicament container with a movable stopper; and a dose delivery mechanism that includes a plunger rod, operably arranged to act on the stopper. The proximal and distal parts are releasably connectable to each other. The proximal part includes a medicament container holder accommodating the medicament container, and the distal part includes the dose delivery mechanism. A plunger rod positioning member is engageable with a proximal end of the plunger rod and with a proximal area of the distal part for positioning the plunger rod in a longitudinal direction in relation to the proximal area. | 12-17-2015 |
20160001019 | LIQUID NEBULIZATION SYSTEMS AND METHODS - Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range. | 01-07-2016 |
20160022726 | VITAMIN B12 NASAL SPRAY AND METHOD OF USE - The present invention relates generally to vitamin B | 01-28-2016 |
20160030435 | PHOSPHODIESTERASE INHIBITOR TREATMENT - Methods and compositions are disclosed for the treatment of taste and smell disorders. The compositions comprise phosphodiesterase inhibitors and are formulated for intranasal administration. | 02-04-2016 |
20160030523 | NOSE BLEED TREATMENT SYSTEM - A nose bleed treatment system for use in treating a patient having a nose bleed uses a nose clip that resiliently clamps the patient's nostrils to provide pressure to help stop the bleeding. A medically effective agent is sprayed in the patient's nostril using a spray bottle that has an elongated tip to apply the agent close to the source of the bleed. The medically effective agent contains at least one of a clot enhancing agent and a vasoconstricting agent. The agent may contain vitamin K as well as a vasoconstricting agent epinephrine with pytonadione (vitamin K1), menaquinone (vitamin K2), menadion (vitamin K3) fibrogen or other suitable medications. The medically effective agents are preferably herbally or mammalian sourced. | 02-04-2016 |
20160030692 | SINGLE-PIECE AEROSOL EXHALATION FILTER AND AN AEROSOL DELIVERY DEVICE INCLUDING THE SAME - An aerosol delivery device for delivering an aerosol to a patient includes a nebulizer configured to generate an aerosol containing droplets of a liquid medicament, an inhalation conduit defining an inhalation passage, an exhalation conduit defining an exhalation passage, and a single-piece filter connected to the exhalation conduit configured to capture at least some of the droplets of the liquid medicament from a gaseous or fluid medium. The single-piece filter includes a continuous, single-piece filter body having a proximal portion and a distal portion, wherein the proximal portion of the filter body has a proximal end that defines an opening configured to connect to the exhalation conduit and the distal portion of the filter body has a closed distal end. | 02-04-2016 |
20160038692 | Internally controlled cell spray dispenser - Internally controlled cell spray dispenser comprises embodiments that are being used to generate spray by controlling a contact between solutions of different cellular composition and the incoming compressed air produced and triggered by an external source of compressed air. In order to obtain desired quality of spray the present apparatus uses the compressed air regulator, and elastic properties of the air channel valve to control both the circumference of the air channel, and the flow of air in to the frontal cone where the main contact between the two fluids is taking place. Reduced air channel is causing a reduction in flow of air and an increased air pressure in the air channel and in the frontal cone promoting discharge of thicker liquids and larger tissue grafts. Releasing the pressure exerted on the air channel valve is causing the air channel to elastically rebound allowing more air under less pressure to enter the frontal cone promoting a discharge of smaller particles suspended in thinner media. | 02-11-2016 |
20160051775 | NEBULIZER DEVICE AND MASK OF INHALATION SOLUTION - The traditions, studies and international practice, prove that the inhalation of hot steams with or without the impurity of a medicine, helps the prevention and treatment of respiratory system diseases in hospitalization or home treatment. The device of application of the therapy is simple, easy to use, safe and affordable cost. This invention concerns a system with: 1) A inventive pipe—conductor of air, with an embodied safe system of electric points and power connections—cables for the supply of the nebulizer device with air and power simultaneously. 2) A nebulizer device that permits the simultaneous heating of the solution and nebula at 35-40° C. via a temperature regulator. In addition it posses system which via the electromagnets or the mechanism opens and closes impellers or a silicone leaf and settles the provision of nebula towards the inhalation mask. 3) A mask of inhalations with conical channels that routes the expired air to the sensor and the inhaled nebula to the mouth and nasal cavity. | 02-25-2016 |
20160058959 | AN INHALER - An inhaler comprising a reservoir of inhalable composition, an outlet valve to control the flow of composition from the reservoir, the valve outlet orifice having a maximum dimension h, measured in the direction of opening when fully opened; an expansion chamber downstream of the valve having a length L and diameter D measured half way along the expansion chamber; and an exit orifice at the downstream end of the expansion chamber, the orifice having a length l and a diameter d; wherein 0.103-03-2016 | |
20160082208 | Inhaler With Orientation Sensor - Various embodiments include an inhaler for oral delivery of medication that includes an actuation detector configured to provide an actuation signal in response to release of the medication from the inhaler, and an accelerometer configured to measure an orientation of the inhaler. The inhaler may include a processor, coupled to the actuation detector and the accelerometer, configured with processor-executable instructions to perform operations to determine a quality of use of the inhaler based on the actuation signal provided by the actuation detector and the orientation of the inhaler measured by the accelerometer. | 03-24-2016 |
20160095992 | Adapter, Inhalation Device, and Atomizer - An inhalation device includes: a chamber for intermediate storage of an aerosol, a first connection for a nebuliser that produces the aerosol, a second connection on a patient side for delivering the aerosol, and a third connection for breathable air, where the chamber is fluidically connected in a valve-free manner on an inlet side to the first connection when the nebuliser is attached, and the chamber is connected to the third connection in parallel on the inlet side via an inlet valve so that the breathable air from the third connection flows into the chamber. | 04-07-2016 |
20160101244 | INHALER FOR A METERED DOSE AEROSOL - An inhaler for delivering a metered dose aerosol, in which a permeable sheet is positioned directly in front of a narrow channel. | 04-14-2016 |
20160101248 | Wearable Wrist Inhaler - A wearable wrist inhaler includes a wristband having a first end and a second end configured for wear about a user's wrist. An inhaler unit is coupled to the wristband displaced from the first end and the second end, the inhaler unit including a housing having a plurality of walls defining an interior area and an outlet port in communication with the interior area. A watch assembly is positioned atop the housing of the inhaler unit, the watch assembly energized by a battery and includes a display configured to indicate a time of day. A dosage chamber including a medicament is positioned in the interior area of the housing. A dispensing assembly is communication with the inhaler medicament that is configured to dispense an individual portion of the medicament via the outlet port upon demand by a user. | 04-14-2016 |
20160106937 | NASAL DELIVERY DEVICE - The present invention provides a method for delivering a substance to the nasal cavity of a subject in which drawing air from a mouthpiece triggers release of a substance to a subject's nasal cavities. The device comprises a container for containing the substance in fluid communication with a nosepiece, a valve with an active configuration and an inactive configuration, and a trigger mechanism to reconfigure the valve from its inactive configuration to its active configuration and vice versa. Drawing air from the mouthpiece, e.g., when the subject takes in air by mouth, activates the trigger mechanism, thereby reconfiguring the valve from its inactive configuration to its active configuration for a predetermined period of time and delivering the substance from the device to a nasal cavity of the subject. | 04-21-2016 |
20160106947 | CPAP FLOW DRIVER FOR USING NEBULIZER WITH CPAP APPARATUS - A CPAP flow driver is adapted to split supplied breathable fluid into a first portion delivered to a venturi throat to generate a pressure drop to draw in ambient air to create a CPAP flow and a second portion that is delivered to a nebulizer to drive the nebulizer. | 04-21-2016 |
20160120220 | AEROSOL-GENERATING SYSTEM COMPRISING A DELIVERY ENHANCING COMPOUND SOURCE AND A MEDICAMENT SOURCE - An aerosol-generating system is provided, including a medicament source and a volatile delivery enhancing compound source. The volatile delivery enhancing compound source includes a first sorption element, a second sorption element downstream of the first sorption element, and a volatile delivery enhancing compound sorbed on the first sorption element and the second sorption element, wherein a rate of release of the volatile delivery enhancing compound from the first sorption element is greater than a rate of release of the volatile delivery enhancing compound from the second sorption element. | 05-05-2016 |
20160121071 | CONTROLLED DELIVERY OF MEDICAL GASES USING DIFFUSION MEMBRANES - A delivery system utilizing a diffusion membrane that regulates the concentration of medical gases that are administered to a patient. A storage vessel contains a neat or pure medical gas under pressure that is in fluid communication with a diffusion membrane. The medical gas is then dispensed at a specified rate by diffusion across a membrane into a carrier gas. The concentration is kept constant by regulating the pressure and carder gas flow. Typical applications are for inhaled gases that are used in patient treatment and care. | 05-05-2016 |
20160144138 | FILTER SYSTEM FOR USE IN MEDICAL DEVICES - The invention relates to a medical hand-held device, in particular an atomizer (1), for dispensing a liquid pharmaceutical preparation from a container with a discharge nozzle for the pharmaceutical preparation and located upstream from the discharge nozzle there is a multiple-stage filter system. | 05-26-2016 |
20160157524 | CALIBRATED DOSE CONTROL - Methods and vaporizer apparatuses that estimate, measure and/or predict the amount of vapor and/or material (including active ingredients) released by the vaporizer apparatus. In particular, described herein are electronic vaporizers and methods of using them that determine a dose/amount of vapor and/or a material in the vapor based primarily or exclusively on the electrical and thermal properties, e.g., power or energy applied to the vaporizing element (e.g., heating coil) and the temperature of the material immediately before and as it is vaporized. Dose information may be used to control operation of the device and/or reported to the user. | 06-09-2016 |
20160158464 | A MESH FOR USE IN A NEBULISER, AND A METHOD OF MANUFACTURING THE SAME - There is provided a mesh for use in forming droplets of liquid in a nebuliser, the mesh comprising a first portion ( | 06-09-2016 |
20160166506 | METHOD AND SYSTEM FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH NEBULIZED ANTICHOLINERGIC ADMINISTRATIONS | 06-16-2016 |
20160166785 | MONITORING OF NEBULIZER USAGE | 06-16-2016 |
20160166786 | SYSTEMS, DEVICES, AND METHODS INCLUDING PERSONAL VAPORIZING INHALERS HAVING CARTRIDGES CONFIGURED TO HOLD MULTIPLE UNIT DOSES | 06-16-2016 |
20160175245 | TREATMENT OF DISEASES ASSOCIATED WITH MOLD AND MYCOTOXIN EXPOSURE | 06-23-2016 |
20160184294 | NASAL DRUG PRODUCTS AND METHODS OF THEIR USE - Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided. | 06-30-2016 |
20160193435 | NASAL DEVICES | 07-07-2016 |
20160199597 | DISPOSABLE AMPOULE FOR AN AEROSOL GENERATING DEVICE | 07-14-2016 |
20160199599 | Nasal Delivery Device and Methods of Use | 07-14-2016 |
20160199604 | INHALATION THERAPY DEVICE FOR USE IN PREMATURE BABIES AND INFANTS | 07-14-2016 |
20160199630 | METHODS AND DEVICES TO PREVENT PREMATURE BIRTH | 07-14-2016 |
20160250437 | SELF-SEALING T-PIECE AND VALVED T-PIECE | 09-01-2016 |
20160374937 | Drug Condensation Aerosols And Kits - The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation products and are characterized by having an MMAD of between 1-3 microns. These aerosols are made by rapidly heating a substrate coated with a thin film of drug having a thickness of between 0.05 and 20 μm, while passing a gas over the film, to form particles of a desirable particle size for inhalation. Kits comprising a drug and a device for producing a condensation aerosol are also provided. The device contained in the kit typically, has an element for heating the drug which is coated as a film on the substrate and contains a therapeutically effective dose of a drug when the drug is administered in aerosol form, and an element allowing the vapor to cool to form an aerosol. Also disclosed, are methods for using these aerosols and kits. | 12-29-2016 |
20160375212 | Methods, devices and Formulations For Targeted Endobronchial Therapy - The present invention provides an improved means of treating tracheobronchitis, bronchiectasis and pneumonia in the nosocomial patient, preferably with aerosolized anti gram-positive and anti-gram negative antibiotics administered in combination or in seriatim in reliably sufficient amounts for therapeutic effect. In one aspect, the invention assures this result when aerosol is delivered into the ventilator circuit. In one embodiment the result is achieved mechanically. In another embodiment, the result is achieved by aerosol formulation. In another aspect, the invention assures the result when aerosol is delivered directly to the airways distal of the ventilator circuit. The treatment means eliminates the dosage variability that ventilator systems engender when aerosols are introduced via the ventilator circuit. The treatment means also concentrates the therapeutic agent specifically at affected sites in the lung such that therapeutic levels of administrated drug are achieved without significant systemic exposure of the patient to the drug. The invention further provides a dose control device to govern this specialized regimen. | 12-29-2016 |
20190143053 | AEROSOL GENERATING APPARATUS WITH REPLACEABLE PARTS | 05-16-2019 |
20190143054 | Nasal Delivery Device and Methods of Use | 05-16-2019 |
20220134025 | ASSEMBLY OF CARTRIDGE AND FLAT HEAT ELEMENT FOR MICROVAPORIZER - A microvaporizer ( | 05-05-2022 |
20220134026 | CONSUMPTION UNIT, INHALER AND MANUFACTURING METHOD - A consumption unit for an inhaler comprises a liquid reservoir, a vaporizer device arranged in the liquid reservoir, and a vent having a flow channel extending in the liquid reservoir to a flow connection of the flow channel to the environment. The liquid reservoir comprises a filling opening, which is closed by means of a first closure part. | 05-05-2022 |