Class / Patent application number | Description | Number of patent applications / Date published |
210647000 | Maintaining critical concentration(s) | 44 |
20080296226 | Solutions, Dialysates, and Related Methods - Solutions, dialysates, and methods for measuring solutes in blood and/or for treating blood. In one aspect of the invention, a method of performing dialysis includes placing a solution in communication with blood of a subject, where a concentration of at least one electrically conductive solute in the solution, prior to being placed in communication with the blood of the subject, is substantially equal to a concentration of the at least one electrically conductive solute in the blood of the subject. | 12-04-2008 |
20090008331 | Hemodialysis systems and methods - The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments. | 01-08-2009 |
20090120876 | Means for removing protein-bound substances - The present invention relates to a means of dialysis for removing protein-bound substances from a biological fluid, especially blood or blood plasma, which contains at least one means for solubilizing protein-binding substances to be removed into the biological fluid and/or dialysis fluid, and to a process for removing protein-bound substances from a biological fluid. | 05-14-2009 |
20090152200 | Optimizing Clearance for Protein-Bound Molecules Using Cascade Filtration Therapy - A hemofiltration system or method removes unwanted molecules from a flow of blood using cascaded first and second hemofilters. Filtration of the blood in first hemofilter raises hemoconcentration of unwanted protein-bound molecules. Combination of a substitution fluid with outflow from the first hemofilter creates a concentration differential between bound and unbound molecules that frees unwanted molecules from protein bonds. Filtration of the combined fluids in a second hemofilter removes the unwanted free molecules. A second substitution fluid may be added to the twice filtered blood fluid for return to a patient. Removal of inflammatory mediators, apoptotic mediators, and certain electrolytes may be effected, and the removal may be optimized by controlling fluid flows and transmembrane pressures. | 06-18-2009 |
20090294360 | Dialysis preparation - The present invention provides a pharmaceutical composition for dialysis wherein the decline of ionized calcium concentration in an acetate-free bicarbonate dialysate comprising no acetic acid and/or sodium acetate is controlled. The present invention further provides a dialysis agent A that comprises electrolytes, citric acid and/or citrate as pH adjuster, and/or glucose, for preparation of bicarbonate dialysates; the agent A characterized by being adjusted by citric acid and/or citrate so as to keep the electrolyte ionized calcium concentration not less than 1 mmol/L in a prepared bicarbonate dialysate. In a specific aspect of the present invention, sodium citrate is used as citrate, and the present invention provides a dialysate obtained from above. | 12-03-2009 |
20100051552 | IN-LINE SENSORS FOR DIALYSIS APPLICATIONS - A system for monitoring water quality for dialysis, dialysis fluids, and body fluids treated by dialysis fluids, is disclosed. The system uses microelectromechanical systems (MEMS) sensors for detecting impurities in input water or dialysis fluid, and in the prepared dialysate. These sensors may also be used to monitor and check the blood of the patient being treated. These sensors include ion-selective sensors, for ions such as ammonium or calcium, and also include amperometric array sensors, suitable for ions from chlorine or chloramines, e.g., chloride. These sensors assist in the monitoring of water supplies from a city water main or well. The sensors may be used in conjunction with systems for preparing dialysate solutions from water for use at home or elsewhere. | 03-04-2010 |
20100084339 | High cut-off hemodialysis membranes for the treatment of chronic hemodialysis patients - The present invention relates to high cut-off hemodialysis membranes for the treatment of chronic hemodialysis (CHD) patients, with the potential to improve long-term survival of these patients by reducing the risk of cardiovascular disease, through down-regulation of monocyte activation in the blood. Monocytes are the major circulating blood cells involved in the progression of cardiovascular disease. High cut-off hemodialysis in chronic dialysis patients results in a sustained decrease in expression of monocyte cell-surface proteins that direct the movement of these cells from the blood to the walls of blood vessels, where they promote the progression of arterial disease (atherosclerosis) that leads to cardiovascular disease (CVD); heart disease, strokes and peripheral vascular disease. | 04-08-2010 |
20100096330 | Method of Determining A Phosphorus Binder Dosage for a Dialysis Patient - The invention is directed to a method of determining a dosage of phosphorus binder for a patient undergoing dialysis treatment to achieve a pre-dialysis serum phosphorus concentration within a desired concentration range while achieving a desired net accumulation of calcium. The method includes determining the dosage of phosphorus binder that will achieve pre-dialysis serum phosphorus concentration of the patient that is within the desired concentration range while accounting for the change in the amount of phosphorus removed by the dialysis treatment when the pre-dialysis serum phosphorus concentration of the patient is within the desired concentration range, determining a dialysate calcium concentration that will result in the desired net accumulation of calcium over a complete dialysis cycle, and dialyzing the patient with a dialysate containing a calcium concentration based upon that determination. | 04-22-2010 |
20100200506 | FLOW BALANCING AND SYNCHRONIZATION SYSTEM AND METHOD, ESPECIALLY FOR CITRATE - A renal failure therapy system includes a blood pump; a citrate pump; and a control unit configured to automatically control the blood pump and the citrate pump to achieve a citrate flowrate that is based on a blood flowrate, so that the flowrates are synchronized. | 08-12-2010 |
20100213127 | METHOD FOR DETERMINING THE REDUCTION RATIO OR THE Kt/V VALUE OF A KIDNEY SUBSTITUTION TREATMENT AND APPARATUS FOR THE REALISATION OF THE METHOD - A method for determining online adequacy parameters for any hemodialysis, hemofiltration and hemodiafiltration treatment modality is provided. Blood equilibrated dialysate samples at the begin and/or at the end of the treatment; and a continuous measurements of waste compounds in the effluent dialysate by means of spectroscopic techniques, are required. With the data coming from the measurements and a simple mathematic approach Kt/V and reduction ratios for different compounds, which are important from the medical point of view, are obtained. | 08-26-2010 |
20100264086 | METHOD AND APPARATUS FOR MONITORING THE SUPPLY OF REPLACEMENT FLUID DURING AN EXTRACORPOREAL TREATMENT OF BLOOD - An apparatus and a method for monitoring the supply of replacement fluid during an extracorporeal treatment of blood is disclosed. Detection of the supply of replacement fluid upstream or downstream of the dialyser or filter is based on a measurement of the optical or physical density of the blood or of a constituent of blood in the extracorporeal circulation. To detect pre- or post-dilution, the blood flow rate and/or the replacement rate and/or the flow rate of the fluid removed from the blood through the dialyser membrane is altered, and the density of the blood or of the constituent of blood is measured upstream and/or downstream of the dialyser. Additionally, an apparatus for treating blood with an apparatus for monitoring the supply of replacement fluid is disclosed. | 10-21-2010 |
20100276367 | METHOD FOR DETERMINING THE PERCENTAGE OF RECIRCULATION IN A FISTULA AND/OR CARDIOPULMONARY RECIRCULATION RELATIVE TO THE TOTAL FISTULA RECIRCULATION AND CARDIOPULMONARY RECIRCULATION - The method according to the invention and the apparatus according to the invention are characterized in that the substitution rate Q | 11-04-2010 |
20110079558 | METHOD OF CONTROLLING DIFFUSIVE SODIUM TRANSPORT IN DIALYSIS - A method of controlling diffusive sodium transport from the dialysate solution to the blood of a patient undergoing hemodialysis treatment or from the blood to the dialysate solution includes calculating SNa | 04-07-2011 |
20110266221 | FLOW BALANCING SYSTEM AND METHOD, ESPECIALLY FOR CITRATE - A renal failure therapy system includes a blood pump; a citrate pump; and a control unit configured to automatically control the blood pump and the citrate pump to achieve a citrate flowrate that is based on at least a blood flowrate. | 11-03-2011 |
20110284464 | METHOD OF SETTING A TIME-VARYING PARAMETER IN A BLOOD TREATMENT APPARATUS - A medical apparatus comprises a control system allowing storage of a number of shaping profiles. Each shaping profile is stored as a plurality of pairs, including a shaping profile reference value and a time interval value. The reference value is represented as fraction, for instance a percentage, of the total weight loss the apparatus should achieve at the end of a treatment time. Each time interval value is represented either as fraction of the total treatment time or as a prefixed actual time interval. The control system calculates the actual weight loss rate versus time profile based on the desired total weight loss, on the desired total treatment time as well as on selected desired shaping profile. | 11-24-2011 |
20120018379 | DEVICE AND METHOD FOR DETERMINING AND CONTROLLING THE CONCENTRATION OF AT LEAST ONE SOLUTE IN A FLUID CIRCUIT - The present invention relates to an apparatus and to a method for the determination and regulation of the concentration of at least one dissolved substance in a fluid circuit, wherein the fluid circuit comprises at least two partial circuits, and wherein the partial circuits are separated by filter in a semi-permeable manner. | 01-26-2012 |
20120261341 | Device and method for conveying a fluid to a filter unit of a medical treatment apparatus - The invention relates to a device and a method for conveying a fluid to a filter unit of a medical treatment apparatus, in particular for conveying a dialysing fluid to a treatment unit, in particular a dialyser or filter of an extracorporeal blood treatment apparatus. The device comprises a balancing unit and a recirculation unit, which comprises one or more chambers. With the balancing unit, it is possible to supply fresh fluid continuously to the recirculation circuit and to discharge used fluid from the recirculation circuit. The supply and discharge of fresh and used dialysing fluid can take place at a flow rate other than the flow rate at which the fluid circulates in the recirculation circuit via the filter unit. | 10-18-2012 |
20120273420 | ELECTROLYTE AND pH MONITORING FOR FLUID REMOVAL PROCESSES - Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session. | 11-01-2012 |
20120305487 | Method for Treating Anemia in Hemodialysis Patients - The present invention relates to a method of treating anemia especially in an EPO resistant hemodialysis patient, comprising hemodialysis with a high cut-off dialysis membrane, wherein the hemodialysis membrane is characterized in that it has a molecular weight cut-off in water, based on dextran sieving coefficients, of between 90 and 200 kD and a molecular weight retention onset in water, based on dextran sieving coefficients, of between 10 and 20 kD, and a ΔMW of between 90 and 170 kD. The invention further relates to a high cut-off hemodialysis membrane for the treatment of anemia in hemodialysis patients, especially EPO resistant hemodialysis patients. | 12-06-2012 |
20130008854 | DIALYSIS MACHINE CALIBRATION - The invention covers a cartridge for use in a hemodialysis machine, the cartridge comprising a dialysate flow path including a dialyzer, the dialysate flow path for delivering a flow of dialysate through the dialyzer; a mixing pump defining a chamber having volume variable between a maximum volume and a minimum volume for receiving a predetermined volume of a first dialysate solution base, second dialysate solution base, and a volume of water; a first dialysate solution base supply conduit having a first positive displacement pump having a first inlet valve and a first outlet valve associated therewith; a second dialysate solution base supply conduit having a second positive displacement pump having a second inlet valve and a second outlet valve associated therewith; a first and second fluid conduit associated joining respective first and second positive displacement pumps with the mixing pump; and a third fluid conduit for connecting the mixing pump outlet to a dialyzer filter inlet. | 01-10-2013 |
20130032537 | LAST-CHANCE QUALITY CHECK AND/OR AIR/PATHOGEN FILTER FOR INFUSION SYSTEMS - Blood treatment system and method for high rate hemofiltration ensures against pyrogenic patient reaction by providing various mechanisms for filtering replacement fluid to remove endotoxins and other safety features including detecting incorrect fluid administration. | 02-07-2013 |
20130056419 | DIALYSATE MIXING AND DIALYZER CONTROL FOR DIALYSIS SYSTEM - A medical dialysis system including a filtration system configured to filter a water stream, a water purification system configured to purify the water stream in a non-batch process, a mixing system, and a dialyzer system. The mixing system includes a supply of dialysate components, a conductivity sensor positioned within a fluid pathway through which the water stream flows, and a control mechanism having a pump configured to control an amount of the one or more dialysate components added to the water stream from the supply. The mixing system can produce a stream of dialysate from mixing the one or more dialysate components with the water stream in a non-batch process. The dialyzer system includes a dialyzer, a plurality of pumps capable of pumping the stream of dialysate across the dialyzer, and another conductivity sensor positioned downstream of the dialyzer within a fluid pathway through which the water stream flows. | 03-07-2013 |
20130081998 | METHOD FOR CONTROLLING OF A FILTRATION RATE, CONTROLLER, AND DEVICES - The present invention relates to a method for controlling a filtration rate during treatment of a body fluid, e.g., during hemofiltration or dialysis, comprising the steps of defining a target relation, or a development during dialysis thereof, between one or more calculated or measured value(s) reflecting the mass, concentration, or the volume of a substance comprised by a patient's tissue or bodily fluid, and one or more calculated or measured value(s) reflecting a patient's distribution space or an approximation thereof; during dialysis repeatedly calculating or measuring value(s) reflecting the mass, concentration or the volume of the substance and/or reflecting the distribution space or an approximation thereof, and determining the relation therebetween at least once; and controlling the filtration rate of the body fluid treatment device such that the determined relation is or approaches the target relation. It also relates to systems for conducting the method, and related computer-readable storage media. | 04-04-2013 |
20130168316 | PREPARATION APPARATUS AND PREPARATION METHOD FOR DIALYSIS FLUID OF VARIABLE BICARBONATE ION CONCENTRATION TYPE, DIALYSATE OF VARIABLE BICARBONATE ION CONCENTRATION TYPE, AND DIALYSIS SYSTEM OF VARIABLE BICARBONATE ION CONCENTRATION TYPE - Technology for preparing a dialysis fluid capable of flexibly changing bicarbonate ion concentration and maintaining concentrations of electrolytes such as potassium, calcium, and magnesium at constant levels during dialysis according to the disease state of a patient. A three-component dialysate containing an agent S containing sodium chloride, an agent B containing sodium bicarbonate, and an agent A containing electrolyte components other than sodium chloride and sodium bicarbonate, with suitable adjustment of the amount of the agent B during dialysis fluid preparation maintains concentrations of trace metal ions such as potassium ions, calcium ions, and magnesium ions in a dialysis fluid at constant levels and flexibly changes the bicarbonate ion concentration therein. Adjusting the ratio between the amount of the agent S and agent B when the dialysate is used also makes it possible to maintain the sodium ion concentration at a constant level or flexibly change the sodium ion concentration. | 07-04-2013 |
20140102983 | DIALYSIS OPTIMIZING METHOD - A method as well as an apparatus is disclosed for determining the efficiency of a currently performed kidney replacement therapy on the dialysis side making use of a dialysis machine which in a first step is operated in a hemodialysis or hemodiafiltration process and in a second step is sequentially changed over to a hemofiltration process or is changed over to a sequential mode in which merely a flow from the blood compartment via the semipermeable membrane to the dialysis fluid compartment of the dialyser is generated in which, according to a third step, a sensor for determining or measuring the concentration at least of uremic toxins in the saturated dialysate or ultra-filtrate which is connected downstream of a dialyser on the dialysis side outputs corresponding measuring signals that are representative of the current concentration at least of uremic toxins in the blood to a calculation or determination unit. | 04-17-2014 |
20140110341 | INTEGRATED WATER TESTING SYSTEM AND METHOD FOR ULTRA-LOW TOTAL CHLORINE DETECTION - A system and method for determining a concentration of total chlorine in dialysis water are provided. The system comprises a main unit housing an iodide/water sample chamber and a reducing agent chamber. An electrode pair bridges the two chambers and generates tri-iodide proportional to the amount of total chlorine in the dialysis water. The electrode pair detects the amount of tri-iodide generated in proportion to the amount of active chloride in the dialysis water. The system is suitable for use in connection with, or for incorporation into, a water purification system for generating dialysis fluid, and may include a display that alerts the user to stop or prevent a hemodialysis treatment if the total chlorine level exceeds a predetermined level. | 04-24-2014 |
20140158623 | SODIUM MANAGEMENT FOR HEMODIALYSIS - Systems and methods for managing the sodium concentration of a dialysate fluid during hemodialysis therapy and adjusting sodium concentration using a sodium management system to generate a sodium-modified fluid. The systems and methods also provide a mechanism for controlled addition of sodium ions to the dialysate to generate a predetermined total sodium concentration in a dialysate. | 06-12-2014 |
20140166579 | Device and Method for Monitoring An Extracorporeal Blood Circuit for the Detection of Air Bubbles - A device for monitoring an extracorporeal blood circuit of an extracorporeal blood treatment device for detection of air bubbles in blood that is conveyed in the extracorporeal circuit by a blood pump, and a method for monitoring an extracorporeal blood circuit for detection of air bubbles, together with a device for monitoring the extracorporeal blood circuit are described. The device and method are based on monitoring the negative pressure in the extracorporeal blood circuit upstream of the blood pump, to allow differentiation between the occurrence of microbubbles which are attributable to cavitation and an entry of air not due to cavitation. When the negative pressure is above a predetermined limit value and microbubbles are detected in the extracorporeal blood circuit, it is deduced that the microbubbles are produced by cavitation and the mechanisms for dissolving the microbubbles are insufficient to remove the microbubbles again before they could reach the patient. | 06-19-2014 |
20140175012 | Method and System of Monitoring Electrolyte Levels and Composition Using Capacitance or Induction - Methods and systems for monitoring fluid levels and electrolyte levels used in a dialysis machine. A receptacle, configured to receive a container, comprises a plurality of curved side panels and a base to form a cylindrical shaped cavity for receiving a container. Each panel includes a conductive material on its inner surface and, optionally, a shielding on its outer surface. An electronics component housed within, or near, the receptacle drives the capacitive process and interprets generated data to determine fluid levels and compositions. An alternate receptacle includes one or two coils wrapped about the container and uses induction to determine fluid level. | 06-26-2014 |
20140197106 | DIALYSIS PREPARATION - The present invention provides a pharmaceutical composition for dialysis wherein the decline of ionized calcium concentration in an acetate-free bicarbonate dialysate comprising no acetic acid and/or sodium acetate is controlled. The present invention further provides a dialysis agent A that comprises electrolytes, citric acid and/or citrate as pH adjuster, and/or glucose, for preparation of bicarbonate dialysate; the agent A characterized by being adjusted by citric acid and/or citrate so as to keep the electrolyte ionized calcium concentration not less than 1 mmol/L in a prepared bicarbonate dialysate. In a specific aspect of the present invention, sodium citrate is used as citrate, and the present invention provides a dialysate obtained from above. | 07-17-2014 |
20140209537 | DEVICE AND METHOD FOR REGULATING A TREATMENT DEVICE - A method and a device are disclosed for regulating an ultrafiltration in a dialysis treatment, in which the blood to be ultrafiltered in an extracorporeal blood circulation ( | 07-31-2014 |
20140217029 | FLUID CIRCUIT FOR DELIVERY OF RENAL REPLACEMENT THERAPIES - A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD) that has a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the flow path. | 08-07-2014 |
20140217030 | SODIUM AND BUFFER SOURCE CARTRIDGES FOR USE IN A MODULAR CONTROLLED COMPLIANT FLOW PATH - Systems and methods for using a sodium chloride source and a buffer source such as sodium bicarbonate in a controlled compliant flow path to generate from water a physiologically compatible fluid having a suitable level of a sodium ion and/or a buffer for use in hemodialysis, hemodiafiltration and hemofiltration. The system has a conditioning flow path that has at least a salination valve or salination pump, and at least one container has at least one solute in excess of the solubility of that solute. At least one of the solutes is a buffer source or sodium chloride. The conditioning flow path is in fluid communication with a controlled compliant flow path. The conditioning flow path can selectively meter fluid into and out of the controlled compliant flow path. | 08-07-2014 |
20140246373 | PROCESS AND DEVICE FOR MONITORING THE SUPPLY OF SUBSTITUTION FLUID DURING AN EXTRACORPOREAL TREATMENT OF BLOOD - The invention relates to a process for monitoring the supply of substitution fluid upstream or downstream of a dialyser or filter arranged in an extracorporeal blood stream. One embodiment provides, for the detection of predilution or postdilution, for measuring the pressure in the blood stream downstream of the dialyser or filter, predilution or postdilution being recognized on the basis of the change in pressure following the shutting off and/or starting up of the substituate pump provided for conveying the substitution fluid. Another embodiment provides for recognizing predilution or postdilution on the basis of the comparison of the oscillating pressure signal attributable to the substituate pump to a characteristic reference signal. The characteristic reference signal to which the pressure signal of the substituate pump is compared is preferably the oscillating pressure signal of a blood pump arranged in the blood stream for conveying the blood upstream of the dialyser or filter. In addition, the invention relates to an extracorporeal blood treatment device with a facility for detecting predilution or postdilution, which device operates according to the processes detailed above. | 09-04-2014 |
20140263063 | MEDICAL FLUID SENSORS AND RELATED SYSTEMS - This disclosure relates to medical fluid sensors and related systems and methods. In certain aspects, a method includes using a medical fluid pump of a medical fluid pumping machine, such as a hemodialysis machine, to deliver medical fluid to a first portion of a cartridge that is positioned within a magnetic field, exciting atoms in the medical fluid in the first portion of the cartridge by applying radio frequency energy to the medical fluid in the first portion of the cartridge, receiving radio frequency energy generated by the excited atoms in the medical fluid in the first portion of the cartridge, and determining a concentration of a substance in the medical fluid based on the received radio frequency energy generated by the excited atoms in the medical fluid in the first portion of the cartridge. | 09-18-2014 |
20140263064 | MEDICAL FLUID SENSORS AND RELATED SYSTEMS AND METHODS - This disclosure relates to medical fluid sensors and related systems and methods. In certain aspects, a method includes reading an indicia of a medical fluid cartridge to determine a volume of a fluid passageway of the medical fluid cartridge indicated by the indicia, receiving radio frequency energy generated by excited atoms in medical fluid in the fluid passageway of the medical fluid cartridge, and determining a concentration of a substance in the medical fluid based on the determined volume of the fluid passageway of the medical fluid cartridge indicated by the indicia and the received radio frequency energy generated by the excited atoms in the medical fluid in the fluid passageway of the medical fluid cartridge. | 09-18-2014 |
20140291244 | METHOD AND DEVICE FOR DETERMINING A RECIRCULATION STATE - A method and a device for determining a recirculation during a dialysis on the basis of the response of the dialysis system to an alteration of a system-related operating value are described. Recirculation may be determined by establishing, at the side of the dialysis liquid, a reference parameter that represents the concentration of uremic toxins from the extracorporeal circulation, and calculating a target parameter for a system-related target operational value from the reference parameter, presetting the system-related target operational value and establishing an actual parameter related to the system-related target operational value, determining an actual comparative value from the actual parameter and the reference parameter related to the system-related target operational value and comparing the actual comparative value with a system-specific target comparative value related to the system-related target operational value, and converting the comparison result into a recirculation degree. | 10-02-2014 |
20140305869 | METHOD AND APPARATUS FOR THE DETERMINATION OF AN INTERNAL FILTRATION DURING AN EXTRACORPOREAL BLOOD TREATMENT - A method and apparatus for the treatment of blood are disclosed allowing for the determination of an internal convection in a blood purification device e.g. in the form of a dialyzer. The internal convection in the purification device can be determined on the basis of pressure differences in the purification device. The blood purification may be, for instance, a hemodialysis or a hemodiafiltration. Pressure sensors serve for measuring the pressures of the blood at the input and/or output of the purification device as well as optionally for detecting the pressure of a cleaning fluid or dialysis fluid at the input and/or output of the purification device. | 10-16-2014 |
20150096936 | SYSTEMS AND METHODS FOR INCREASING CONVECTIVE CLEARANCE OF UNDESIRED PARTICLES IN A MICROFLUIDIC DEVICE - A microfluidic device for increasing convective clearance of particles from a fluid is provided. A network of first channels can be separated from a network of second channels by a first membrane. The network of first channels can also be separated from a network of third channels by a second membrane. Fluid containing an analyte can be introduced in the network of first channels. Infusate can be introduced into the network of second channels, and waste-collecting fluid can be introduced into the network of third channels. A pressure gradient can be applied in a direction perpendicular to the direction of fluid flow in the network of first channels, such that the analyte is transported from the network of first channels into the network of third channels through the second membrane. | 04-09-2015 |
20150129499 | APPARATUS AND METHOD FOR DETERMINING A PARAMETER INDICATIVE OF THE PROGRESS OF AN EXTRACORPOREAL BLOOD TREATMENT - An apparatus for extracorporeal treatment of blood ( | 05-14-2015 |
20150359954 | AUTHENTICATION SYSTEM UTILIZED IN A SORBENT-BASED DIALYSIS SYSTEM FOR THERAPY OPTIMIZATION - A dialysis authentication and management system comprising at least one dialysis component having at least one authentication component affixed thereon. The dialysis component can be any one of a dialyzer, sorbent cartridge, recharger or any other dialysis component. The authentication component can be selected from the group of a radio-frequency identification marker, a bar code, a one-wire security component, and a wireless authentication component. The authentication system can ensure that all components used are in proper usable condition and/or certified. The system can also manage the recharging of rechargeable components, and optionally manage dialysis therapy. | 12-17-2015 |
20150367059 | UREASE INTRODUCTION SYSTEM FOR REPLENISHING UREASE IN A SORBENT CARTRIDGE - An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The system is configured to allow insertion of a urease pouch, injection of a urease solution, or addition of a urease cartridge, into a dialysis cabinet containing a dialysis flow loop. The urease can be dissolved and the resulting urease solution added to the sorbent cartridge in the flow loop to replenish the urease within the sorbent cartridge. The sorbent cartridge can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate. | 12-24-2015 |
20160018347 | DESIGNS, SYSTEMS, CONFIGURATIONS, AND METHODS FOR IMMITTANCE SPECTROSCOPY - Described herein are devices, systems, and methods for determining the composition of liquids, including the identity of one or more drugs in the liquid, the concentration of the drug, and the type of diluent using immittance spectroscopy. These devices, systems and methods are particularly useful for describing the identity and, in some variations, concentration of one or more components of a medical liquid such as intravenous fluid. | 01-21-2016 |
20160109398 | Method and System of Monitoring Electrolyte Levels and Composition Using Capacitance or Induction - Methods and systems for monitoring fluid levels and electrolyte levels used in a dialysis machine. A receptacle, configured to receive a container, comprises a plurality of curved side panels and a base to form a cylindrical shaped cavity for receiving a container. Each panel includes a conductive material on its inner surface and, optionally, a shielding on its outer surface. An electronics component housed within, or near, the receptacle drives the capacitive process and interprets generated data to determine fluid levels and compositions. An alternate receptacle includes one or two coils wrapped about the container and uses induction to determine fluid level. | 04-21-2016 |