Entries |
Document | Title | Date |
20080199358 | AUTOMATIC ANALYZER - An object of the present invention is to provide an automatic analysis method and an automatic analyzer which are suitable for improving throughput by changing reagents during analysis without placing a load on an operator, and without stopping the analysis. There is provided an automatic analysis method comprising the steps of: while moving a reagent transfer mechanism with respect to a reagent pipettor, dispensing a reagent placed in the reagent transfer mechanism by use of the reagent pipettor to cause a sample to react with the dispensed reagent; and measuring the reacted sample so as to analyze specified analysis items of the sample. A reagent is transferred from a reagent storage unit to a reagent changing mechanism. Then, the reagent changing mechanism is moved in synchronization with the reagent transfer mechanism so that reagents are changed during the synchronization. | 08-21-2008 |
20080206099 | MAGNETIC SEPARATOR AND ANALYZER USING THE SAME - An analyzer which collects magnetic particles for immunological analysis includes a magnetic separator adapted to efficiently separate within a short time a reaction product formed by bonding substances such as an object to be measured and the magnetic particles, and a nonmagnetic component other than the reaction product, from a liquid mixture in a vessel of the magnetic separator To perform the separation, a magnet complex having multiple magnets and magnetic materials stacked in alternate form so that magnetic pole pieces on opposed sides of each magnet are homopolar, is disposed outside the vessel that holds a liquid in which the magnetic particles are suspended. | 08-28-2008 |
20080206100 | AUTOMATIC ANALYZER - The automatic analyzer uses a sample pipetted into a sample vessel to perform analysis, the sample vessel being repeatedly cleaned and used. In order to prevent contamination of the sample vessel, which is caused by the measurement of general biologically-derived samples, from influencing the analysis, the automatic analyzer uses a specified sample vessel to measure a standard solution so that the calibration of each analysis item is carried out. The automatic analyzer does not use the sample vessel in question for analysis of other biologically-derived samples. | 08-28-2008 |
20080206101 | Fluidic array devices and systems, and related methods of use and manufacturing - The instant application provides a fluidic array device having an elastomeric body that provides easy fluidic control of the device. The elastomeric body may include plurality of intersecting row and column channels. Reactions may occur at the intersection spots formed by the intersecting channels. Pinching applied at suitable locations along the channels enables the channels to be opened or closed, and thus provides control of fluids pumped through the device. The surfaces of the channels and intersection spots may be engineered to have certain properties. In particular, the intersection spots may be nanoengineered to have surface properties differing from those of the channels, and thus reactions may be selectively controlled to occur only, or highly preferentially, in the intersection spots. | 08-28-2008 |
20080206102 | Apparatus and methods for high-resolution and high-sensitivity assays - An apparatus allows separation, fractionation isolation and fraction collection simultaneously. The device consists of two major pieces, with one piece slides relatively to the other to facilitate the switching between separation and fractionation. | 08-28-2008 |
20080213130 | DIAGNOSTIC-NANOSENSOR AND ITS USE IN MEDICINE - This invention relates generally to biosensor technology, and pertains more particularly to novel multifunctional biosensors based on ordered arrays of metallic, semiconductors and magnetic nano-islands for medical, biological, biochemical, chemical and environmental applications. | 09-04-2008 |
20080213131 | PARTICLE AGGLUTINATION-EVALUATING CONTAINER - A particle agglutination-evaluating container for immunological analysis, based on an agglutinate formed in an agglutination reaction between an antibody- or antigen-containing sample and agglutination particles, includes a transparent container body having a bottom face including a sloping bottom face and a raised bottom face extended in a horizontal direction at the top of the sloping bottom face to form an obtuse angle with the sloping bottom face, and a fluidal separation layer containing insoluble particles which are filled in the container body and where the agglutination particles are separated according to the agglutination degree, wherein agglutination is evaluated by observation from the bottom of the container body, where the agglutination reaction is judged positive when the agglutination particles are observed through the raised bottom face, negative when observed at the bottom end of the sloping bottom face, and weakly positive when observed in the middle of the sloping bottom face. | 09-04-2008 |
20080213132 | AUTOMATIC ANALYZER - In an automatic analyzer, effect is reduced or prevented of a change in temperature and volume of components making up a mechanism for dispensing a reagent and a sample or a system liquid on an amount of sample and reagent per one dispensing cycle. One or a plurality of components making up the mechanism for dispensing the reagent and the sample is mounted with a sensor for measuring a temperature of the component. The dispensing mechanism further includes a sensor for measuring a temperature of the system liquid at one or a plurality of locations. Control is thereby provided, based on temperature information provided by the temperature sensor, to vary an amount of operation of a component that varies an amount of reagent and sample to be dispensed or to make the temperature of the system liquid equal to, or close to, the temperature of the component. | 09-04-2008 |
20080219888 | Multi-Channel Flow Cells - A multi-channel flow cell can allow for reduced cross-contamination in sample loading and the ability to observe activity within the flow cell once the channels are loaded. A multi-channel flow cell includes a plurality of independently-addressable channels sandwiched between a two substrates. Each of the channels can be coated with a layer that facilitates support-binding of an analyte. Each of the channels terminates on one end in an inlet and on the other end in an outlet. A loading block having inlet ports that match the inlets of the channels can be mated to the inlets of the channels, and an outlet block can be mated to the outlets of the channels. Analytes can be introduced into the channels via the inlet ports of the loading block and are pulled through the channels by capillary action or by vacuum. Once analyte has been introduced into each of the channels, the loading and outlet blocks can be removed and the device turned over. Such a flow cell can be used for streamlining the process of reaction and interrogation of biochemical assays at the microfluidic level. Reagents can be introduced into each of the channels of the flow cell for chemical reactions therein, excess reagent being washed out through the channel outlets. Observation of optically-detectable moieties is then conducted. With such a flow cell optical labels associated with incorporation in a sequencing-by-synthesis reaction can be observed. | 09-11-2008 |
20080219889 | System for Automatically Processing a Biological Sample - The invention provides a system, a processing apparatus, a sample unit, a reagent unit and a method for processing a biological sample in the inside of the sample unit. The system comprises at least a processing apparatus and a sample unit, the sample unit comprises a plurality of microfluidic elements, the processing apparatus comprises actuation means capable of actuating at the microfluidic elements such that a quick, cheap and accurate analysis of the biological sample is possible. | 09-11-2008 |
20080226500 | Chemical Analytic Apparatus and Chemical Analytic Method - A chemical analytic apparatus of the present invention is the one which proposes that a miniaturization, a making low-cost and portability are possible and also the operation of each process of separation, concentration and dilution of specimen is possible, and which includes: an introduction means (S | 09-18-2008 |
20080226501 | Microfluidic Device With Finger Valves - A microfluidic device ( | 09-18-2008 |
20080226502 | Microfluidic Methods and Support Instruments - A method of performing a test of a liquid sample using a microfluidic device having at least one flow path may include introducing the liquid sample into the flow path and subjecting the microfluidic device to at least one linear motion with an acceleration sufficiently high to affect the flow of the liquid sample in the flow path, the test preferably being a diagnostic test. A support instrument for use in supporting a microfluidic device may include a sustaining arrangement capable of sustaining a microfluidic device, and a motion arrangement capable of subjecting a sustained microfluidic device to at least one linear motion. | 09-18-2008 |
20080226503 | Method for selective detection of peptides using molecularly imprinted sensors - This invention presents a fast and effective method to detect macromolecules such as peptides. Using a multifunctional chiral monomer, it combines molecular imprinting polymerization technology with a quartz crystal microbalance for detection of peptides to the ng/ml scale. | 09-18-2008 |
20080233006 | Method and Apparatus For Determining the Oxygen Permeability of a Polymer - The present invention is relates to an apparatus and method for the determination of the oxygen gas permeability of a polymer. In one embodiment, the present invention relates to an apparatus and method for determining the oxygen gas permeability of a polymer membrane (e.g., a polydimethylsiloxane and/or polysiloxane polymer or copolymer). In still another embodiment, the present invention relates to oxygen gas permeable polymer compositions. | 09-25-2008 |
20080233007 | Nondestructive Portable Sugar Level Measurement Instrument with Applications in Food Production and Distribution Industries - We present a device for measuring levels and concentrations of sugar in objects that is suitable for food production and distribution industries. One of the key characteristics of the device is its ability to perform the measurement without destructing the product, and therefore, maintaining its quantity and quality. | 09-25-2008 |
20080240985 | Nucleic Acid Assays - The present invention relates to the detection of specific nucleic acid sequences, either by a process of amplification of specific nucleic acid sequences or not. More particularly the invention provides for improved compositions and methods for reducing the chance for contamination from manipulation of reagents, internal controls for amplification, and the use of automated apparatus for the automated detection of one, or more than one amplified nucleic acid sequences. | 10-02-2008 |
20080240986 | Assaying device for collecting, storing, and testing fluid samples - An assaying device for collecting, storing, and assaying fluid samples includes a container and a cap. Disposed within the cap is a chamber for housing an assay testing system. A flow channel is provided for communicating between the container and the testing system and enabling the fluid samples to be introduced to the testing system from the container upon change of orientations of the device. A tamper-proof flow control valve and a key are provided for regulating the flow of the fluid sample in the flow channel, thereby, the assaying can be activated only when desired by an authorized person with the key. | 10-02-2008 |
20080240987 | Micro fluidic device and method for producing micro fluidic device - A micro fluidic device comprises a micro channel in which a plurality of fluids form laminar flows and are supplied, wherein an inner wall of the micro channel comprise a protruding part that is substantially parallel to the flows of the fluids and protrudes in directions substantially vertical to interfaces formed by the plurality of fluids. | 10-02-2008 |
20080240988 | SAMPLE ANALYZER - A sample analyzer: measures a measurement sample including a sample and a reagent; creates a calibration curve based on first measurement data obtained by measuring a measurement standard sample including a standard sample and the reagent; provides calibration curve specifying information for specifying the calibration curve to the calibration curve; acquires an analysis result by processing second measurement data obtained by measuring the measurement sample based on the calibration curve; and stores the analysis result and the calibration curve specifying information provided to the calibration curve used in the process of the second measurement data in correspondence to each other. | 10-02-2008 |
20080240989 | AUTOMATIC ANALYZER - An automatic analyzer of the present invention includes a status table storing the status of each analysis module and reagent information identifying each reagent, the supply of which is exhausted, and allowing tracking of the status of each analysis module, etc. The automatic analyzer determines, based on the status table, whether and how it can continue current analysis, and stores the determination results in its instruction information table. The instruction information table stores analysis-unit or -module operating information and information to be supplied to the user or operator. The analysis-unit operating information includes instructions for the analysis modules to initiate an analysis in a normal manner, finish an analysis in a normal manner, omit a pre-analysis operation, omit a post-analysis operation, or stop sampling, etc. Further, the reagent information and the analysis module status are updated each time a reagent container is replaced by the operator. | 10-02-2008 |
20080240990 | Adaptor for sample vial - The invention relates generally to a sample vial adaptor for interfacing a sample vial with the sample port of a diagnostic instrument, in particular a sample vial containing a patient body fluid sample with the sample port and sample pathway of a multi-use diagnostic instrument. Embodiments of the sample vial adaptor according to the invention generally include a short exterior vent tube having one end in communication with a chamber having a vent, an interior collection tube that is longer than the short exterior vent tube, axially positioned in the lumen of the short exterior vent tube and extending to a capillary outlet that is located on the portion of the inner collection tube that is outside of the short exterior vent tube and outside the vented chamber. | 10-02-2008 |
20080240991 | Sample Analyzer - A sample analyzer is disclosed that comprising: a first reagent container to hold a first reagent container with a first record section which contains a first reagent management information; a second reagent container holder to hold a second reagent container with a second record section which contains a second reagent management information; a first information reader; a second information reader; a registration section for registering the combination of the first reagent and the second reagent based on the first reagent management information; a measurement section for conducting a measurement of a predetermined analysis item by using the first reagent and the second reagent corresponding to the combination registered by the registration section; and a processing section for processing a measurement result obtained by the measurement section, and for obtaining an analysis result of the sample. | 10-02-2008 |
20080240992 | STIRRER,VESSEL, AND ANALYZER - A stirrer is for stirring a liquid retained in a vessel with a sonic wave. The stirrer includes a sonic wave generating unit and a drive control unit. The sonic wave generating unit includes plural sound generators each having a different resonance frequency, for emitting the sonic wave generated from the sound generator toward the liquid. The drive control unit switches the sound generator which generates the sonic wave to a specific sound generator among the plural sound generators by changing a frequency of a drive signal input to the sonic wave generating unit. | 10-02-2008 |
20080247907 | Dual inlet microchannel device and method for using same - A dual inlet microchannel device and a method for using the device to perform a flow-through kinetic assay are described. A microplate having an array of the dual inlet microchannel devices and in particular their specially configured flow chambers is also described. Several embodiments of the dual inlet microchannel devices and specially configured flow chambers are also described. | 10-09-2008 |
20080247908 | Sensor Chip for a Biosensor - The invention relates to a microchip ( | 10-09-2008 |
20080247909 | Sample suction apparatus - A sample suction apparatus includes: first through third members; a drive source; and a suction needle provided on the third member. The drive source reduces a distance between the first member and the third member to perform: a first action of shifting the first member toward the third member to contact the first member with a portion of a specimen vessel; a second action of shifting the second member together with the third member toward the first member to contact the second member with another portion of the specimen vessel so that the specimen vessel is sandwiched between the first and second members; and a third action of shifting the third member toward the first member to bring the third member close to the second member so that the suction needle is inserted in the specimen vessel. | 10-09-2008 |
20080253928 | Substrate for Biochip and Method for Manufacturing Substrate for Biochip - A substrate for biochips has a substrate surface having a reaction region capable of reacting with biological substances and a non-reaction region not reacting with the biological substances, sunken bottomed wells formed in the substrate surface, and a layer of a material capable of reacting with the biological substances having a surface exposed only at the bottoms of the bottomed wells, the exposed surface forming the reaction region. | 10-16-2008 |
20080253929 | MICRO- OR NANO-FLUIDIC CHIP FABRICATED WITH NORLAND OPTICAL ADHESIVE AND BIOANALYSIS PLATFORM PRODUCED BY USING THE SAME - The present invention relates to a micro- or nano-fluidic chip fabricated with a NOA. Said micro- or nano-fluidic chip comprises sequentially an inlet, a channel, and an outlet, wherein the channel has pillar in the region of the outlet to prevent beads from flowing out. The surface of channels in the micro- or nano-fluidic chip of the invention is hydrophilc, which generates spontaneous flow in the channels by a capillary force without any extra external pumping. | 10-16-2008 |
20080253930 | CODED TUBES AND CONNECTORS FOR MICROFLUIDIC DEVICES - Tubes and connectors for microfluidic devices are described. The tubes are provided with a coding on their external surface for example, to allow easier identification. The connector comprises a plurality of through holes going through the connector. Each through hole can accommodate a pin for connection of microfluidic device ports on one side of the pin and connection of a reagent or sample liquid tube on the other side of the pin. | 10-16-2008 |
20080260581 | Sampling and Assay Device - A sampling and assay device comprises at least three chamber portions ( | 10-23-2008 |
20080260582 | Method for Displacing Small Amounts of Fluids in Micro Channels by Means of Acoustical Waves - A method is provided for displacing small amounts of fluids in micro channels, in which an amount of fluid is introduced into a channel system which has at least one area which corresponds in a topological manner to a ring, such that a closed path of the fluid is possible, and acoustic waves, which have at least one asymmetrical component on the plane of the channel system, are radiated into the fluid, this component defining the direction of displacement of the fluid. A micro channel system for carrying out the method is also provided. | 10-23-2008 |
20080260583 | Micro-Fluidic Device Based Upon Active Matrix Principles - A micro-fluidic device ( | 10-23-2008 |
20080267822 | ANALYSIS DEVICE WITH EXCHANGEABLE TEST ELEMENT MAGAZINE - A measurement system is provided which comprises an analysis device with at least one of a measurement function and a sample collection function, and also at least one magazine configured to receive at least one consumer element therein. The magazine comprises a magazine housing having a pair of openings. The magazine is designed as an exchangeable magazine that can be selectively operatively connected to the analysis device. The analysis device further comprises a closure mechanism having at least one sealing element which is designed to convey at least one consumer element from one of the openings. The sealing element is further configured to sealingly close the openings of the magazine when the sealing element is disposed therein. | 10-30-2008 |
20080267823 | Identification Of A Strip Type By The Meter Using Conductive Patterns On The Strip - A test strip including a reagent end for receiving a body fluid sample and an insertion end which is received at a test strip receptacle slot of a measuring device, the insertion end including one or more on-strip indicators for indicating to a measuring device that the test strip has been inserted into the device so that the device will power-up in preparation to perform a test, and the one or more on-strip indicators having a distinct pattern indicating whether calibration is automatic or whether the user needs to input calibration information to the said device, and corresponding methods are disclosed. | 10-30-2008 |
20080286151 | APPARATUS FOR PERFORMING HEAT-EXCHANGING CHEMICAL REACTIONS - An apparatus for controlling the temperature of a reaction mixture contained in a chamber of a reaction vessel comprises a thermal surface for contacting a flexible wall of the chamber and an automated machine for increasing the pressure in the chamber. The pressure increase in the chamber is sufficient to force the flexible wall to conform to the thermal surface for good thermal conductance. The apparatus also includes at least one thermal element for heating or cooling the surface to induce a temperature change within the chamber. | 11-20-2008 |
20080286152 | Hyperbrached Polymer for Micro Devices - The invention relates to novel polymer-based microstructures, with outstanding shape accuracy and cost-effective processing. The novel polymers are based on hyperbranched macromolecules and enable remarkable property combination such as reduced shrinkage and associated low stress, high shape fidelity and high aspect ratio in patterned microstructures, with additional benefit of fast and low-cost production methods. The invention also relates to methods to produce these microstructures. The polymer-based microstructures are relevant for, but not limited to micro- and nano- technologies applications, including lab-on-a-chip devices, opto-electronic and micro- electromechanical devices, optical detection methods, in fields of use as diverse as automotive, aerospace, information technologies, medical and biotechnologies, and energy systems. | 11-20-2008 |
20080292500 | Flow cytometry for high throughput screening - The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means for introducing a separation gas between each of the plurality of samples in the fluid flow stream; and means for selectively analyzing each of the plurality of samples for the particles. The present invention also provides a flow cytometry method employing such an apparatus. | 11-27-2008 |
20080292501 | SYSTEM FOR AUTOMATIC OPENING OF REAGENT VESSELS - The invention relates to an analysis system which, by means of a reagent cartridge opening module, permits automatic opening of reagent vessels which are closed by screwing. The reagent cartridge opening module for this purpose has catch elements which can lock securely against rotation in correspondingly configured catch elements of a reagent vessel lid. In addition, the reagent cartridge opening module and the reagent vessel lid are connected via snap-in elements, so that transport of the reagent vessel lid perpendicular to the plane of the rotational movement is possible. | 11-27-2008 |
20080305005 | Composite Ceramic Body and Manufacturing Method Thereof, Microchemical Chip, and Reformer - A composite ceramic body and a method thereof are provided. The composite ceramic body comprising a first bonding body comprising a ceramic containing Si ingredient, and a second bonding body bonded to the first bonding body through a bonding material containing, as main ingredient, a Si compound which includes the element common to the Si ingredient contained in the first bonding body. The first and second bonding bodies can be bonded strongly and uniformly without any adhesive. Since the composite ceramic body has high bonding strength, it is applicable to microchemical chips and reformers. | 12-11-2008 |
20080305006 | MICROFLUIDIC APPARATUS HAVING FLUID CONTAINER - A microfluidic apparatus having a substrate including a channel through which a fluid is conveyed, a fluid container in which at least one kind of fluid is accommodated and which is disposed on the substrate so as to allow the fluid to flow toward the channel, and a fluid flow controller which controls a flow of the fluid toward the channel from the fluid container. | 12-11-2008 |
20080305007 | HYDROGEL COMPOSITIONS - The invention relates to compositions comprising a hydrogel matrix, where the matrix comprises poly(ethylene glycol) dimethyacrylate (PEGDMA), an acrylate, such as methacrylic acid (M) and methyl methacrylate (MMA), as well as 2-hydroxy-2 methyl propiophenone (HMPP). | 12-11-2008 |
20080305008 | Micro-Fluidic Structures - A micro-fluidic structure such as a bio-sensor device has a dispensing element for fluid and a destination zone in communication with, and downstream of, the dispensing element. A bridge structure extends to the dispensing element and promotes fluid passage across the bridge structure from the dispensing element toward the destination zone. | 12-11-2008 |
20080311000 | Micro-Fluidic System - Micro-fluidic systems comprise components ( | 12-18-2008 |
20080311001 | REACTION CUVETTE FOR AUTOMATIC ANALYZER AND METHOD OF SURFACE TREATMENT FOR REACTION CUVETTE - The present invention provides a highly reliable reaction cuvette in which air bubbles are adhered little and mutual contamination can be prevented among samples and reagents in adjoining reaction cuvettes, a method of surface treatment for a reaction cuvette, and an automatic analyzer with the reaction cuvette mounted therein. | 12-18-2008 |
20080311002 | Analytical devices with integrated desiccant - An analytical device for performing an assay to determine the presence or approximate quantity of at least one analyte in a liquid sample is described. The device is manufactured to include an integrated desiccant within at least a test strip of the device. Addition of an integrated desiccant within the device improves signal to noise ratio, eases the manufacturing process, and saves in cost of production of the device. | 12-18-2008 |
20080317631 | Nanotube Device and Method of Fabrication - A nanotube device and a method of depositing nanotubes for device fabrication are disclosed. The method relates to electrophoretic deposition of nanotubes, and allows a control of the number of deposited nanotubes and positioning within a defined region. | 12-25-2008 |
20080317632 | Microchannel and Microfluid Chip - There is provided a microchannel for allowing a liquid to flow. At least part of an inner surface of the microchannel is provided with a bubble trapping means for trapping any bubbles present in a liquid sample. This allows bubbles present in the liquid sample to be efficiently trapped even though only a tiny amount of sample may be used, regardless of the size of the microchannel. As a result, the flow of a fluid is not disrupted and thus measurement, detection, and so forth can be carried out accurately and quickly without hampering the measurement system. | 12-25-2008 |
20080317633 | Multiplex lateral flow devices and methods - A lateral flow device includes a porous medium layer having a two-dimensional shape in plan view defined by one or more peripheral edges wherein the two dimensional shape includes a plurality of testing regions separated from one another by spaces between portions of the one or more peripheral edges. The porous medium layer further includes a fluid-receiving region in capillary flow communication through the porous medium layer to the testing regions. | 12-25-2008 |
20090004058 | Device for handling and analysis of a biological sample - An apparatus for detection of an analyte of interest in a solid, semi-solid, or liquid biological sample, using a lateral flow assay test strip, is described. The apparatus minimizes sample handling and manipulation upon introduction of the sample into a sample-receiving chamber and transfer of the sample to a test chamber containing the assay strip. | 01-01-2009 |
20090004059 | METHOD AND APPARATUS FOR PRECISE TRANSFER AND MANIPULATION OF FLUIDS BY CENTRIFUGAL AND OR CAPILLARY FORCES - A micro-liter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved through one or more sample wells arrayed within a small flat chip via interconnecting capillary passageways. The passageways may be either hydrophobic or hydrophilic and may include hydrophobic or hydrophilic capillary stops. | 01-01-2009 |
20090010804 | Portable apparatus for improved sample analysis - The present invention is an improved apparatus for sample analysis. The apparatus employs an assay component containing a membrane having one or a plurality of analyte-specific binding agents attached thereto, a means for absorbing liquid, and a piston means for drawing analytes through said membrane into said means for absorbing liquid. The apparatus is configured to be portable and provide a detector for detecting binding of an analyte to an analyte-specific binding agent, a plurality of data acquisition components, and a computer for integrating, analyzing and storing the detected analyte specific binding and acquired data. | 01-08-2009 |
20090010805 | ASSAYING DEVICE AND METHOD OF TRANSPORTING A FLUID IN AN ASSAYING DEVICE - An assaying device includes one or more detectors, a transporter and inlet that is connected to the one or more detectors by a one or more channels. The transporter includes one or more sealed, vacuum-containing chambers being connected to the channels, wherein each of the chambers includes an electrically activated puncture. The puncture is configured to puncture a wall of a chamber and cause a differential pressure in the one ore more channels, and thereby transport a fluid from the inlet to the one or more detectors. | 01-08-2009 |
20090016932 | Micro Chamber - A microfluidic device is provided including at least one chamber accessible by microfiuidic channels characterized in that the surface of the channels and the chambers are patterned and comprise hydrophilic and hydrophobic areas. The surface energy in correspondence of the areas, i.e., the capillary force, being such that a liquid can be guided along the hydrophilic path, enter the chamber from one side, wet part of one surface of the chamber as a thin layer without touching the opposite surface of the chamber, thus avoiding to fill the volume inside the chamber in correspondence of the hydrophilic pattern until a second liquid, either sequentially or in parallel, comes to wet part of the opposite surface of the chamber and eventually touches the first liquid layer, resulting in a sudden coalescence and efficient mixing between the liquids. | 01-15-2009 |
20090022625 | BIOCHEMICAL ANALYZER AND METHOD OF CONTROLLING INTERNAL TEMPERATURE OF THE BIOCHEMICAL ANALYZER - Provided is a biochemical analyzer in which a microfluidic biochemical assay may be performed. The analyzer includes: a microfluidic device loading space including a microfluidic device supporting unit detachably supporting a microfluidic device including an energy application region in which an energy is applied; an energy source loading space including an energy source applying the energy to the radiation application region; and an isolation wall isolating the microfluidic device loading space and the energy source loading space to prevent heat transfer between the microfluidic device loading space and the energy source loading space and including a window through which the energy can be transmitted. A method of controlling an internal temperature of the biochemical analyzer is also provided. | 01-22-2009 |
20090022626 | AUTOMATED ANALYZER - A conventional automated analyzer has a mechanism for performing a stirring operation and a mechanism for performing a pipetting operation. The mechanisms are independent of each other. The time interval between the stirring operation and the pipetting operation is at least several seconds. A solid particle starts to settle out at the time of termination of the stirring operation. In the pipetting operation, an operation for suctioning a liquid is performed during a transient period of the process in which the solid particle settles out. The suction of the liquid containing a solid particle during the transition period of the process may cause a variation in the number of solid particles contained in the liquid pipetted. The problem is solved by means for simultaneously performing an operation for stirring a liquid reagent containing a solid particle and an operation for maintaining the reagent. | 01-22-2009 |
20090028755 | MICROFLUIDIC DEVICES AND METHODS - Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in a discharge aperture. | 01-29-2009 |
20090035181 | MOBILE ROBOT AND CLINICAL TEST APPARATUS USING THE SAME - A clinical test apparatus employing a mobile robot is provided. The clinical test apparatus includes a stage unit, a test station provided in the stage unit and configured to perform a clinical test, a mobile robot configured to move on a top surface of the stage unit and to transfer a plate on which samples and reagents are loaded to the test station, and a docking unit disposed in the stage unit and configured to reset a position of the mobile robot. A variety of test stations for a clinical test can be integrated, and multiple tests can be performed at the same time through a plurality of mobile robots. | 02-05-2009 |
20090041624 | FLUIDIC STRUCTURE AND METHOD FOR PRODUCTION OF A FLUID STRUCTURE - A fluidic structure and a method for production of a fluidic structure are provided. The method may comprise, in order, introducing at least one externally accessible opening into at least one base substrate of the fluidic structure, partially introducing at least one section of a fluidic conductor, which has at least one inner lumen and at least one conductor wall, in particular of a tube or flexible tube, into the at least one opening, introducing at least one curable fluid sealing material into the at least one opening, entirely or partially curing the at least one fluid sealing material, and producing at least one connecting channel between at least one inner lumen in the at least one fluidic conductor and at least one fluid channel in the fluidic structure, the at least one connecting channel passing through at least one conductor wall. | 02-12-2009 |
20090041625 | Auto-calibration label and method of forming the same - An auto-calibration circuit or label ( | 02-12-2009 |
20090041626 | INSTRUMENTATION SYSTEMS AND METHODS | 02-12-2009 |
20090041627 | PACKAGING OF MICROFLUIDIC DEVICES - A microfluidic device containing liquid reagents having an extended shelf life contains the liquid reagents in micro-reservoirs that limit the escape of moisture to less than 10% over the shelf life of the device. The micro-reservoir preferably is made of polypropylene and covered with a metallized plastic film. | 02-12-2009 |
20090041628 | AUTOMATIC ANALYZER - An automatic analyzer includes a wastewater suction unit that causes a suction nozzle to suction a reaction wastewater from each of plural reaction vessels transferred to a disposal position, transfers the plural suction nozzles to a cleaning position to make the suction nozzles suction a cleaning liquid, and clean the suction nozzles. The wastewater suction unit includes a pressure detector that is arranged near the suction nozzle in a pipe that guides a negative pressure for suction to each of the suction nozzles to detect pressure in each of the suction nozzles at time of suctioning of the reaction wastewater, a vessel determination unit that determines whether the reaction vessel is present or not at the disposal position, and a clog determination unit that determines whether each of the suction nozzles is clogged or not based on change in pressure in the suction nozzle and presence/absence of the reaction vessel. | 02-12-2009 |
20090053105 | Sensor Chip - There is provided a sensor chip including: a base plate; a cover layer; a hollow reaction portion provided between the base plate and the cover layer, in which a reaction is performed between a sample and a reagent applied thereinto; a sensing member constructed of an electrode which is exposed to the hollow reaction portion; and a sample inlet for conducting the sample to the hollow reaction portion, wherein
| 02-26-2009 |
20090053106 | Autonomous microfluidic apparatus - The present invention relates to an autonomous microfluidic apparatus. The autonomous microfluidic apparatus is substantially a substrate having a microchannel structure arranged thereon. As a microfluid is being filled in a loading well situated upstream of the microchannel structure, the microfluid is affected by interactions between gravity, adhesive force and surface tension and thus driven to flow downstream in the microchannel structure while filling a plurality of manifolds formed in a area situated downstream of the microchannel structure, so that accurate and autonomous quantification and separation of the microfluid using the plural manifolds, each having a specific length, can be achieved and provided for biomedical inspection and analysis. | 02-26-2009 |
20090053107 | MICROFLUID DEVICE AND METHOD FOR SETTING UP A MICROFLUID DEVICE - This invention concerns a microfluid device ( | 02-26-2009 |
20090060786 | MICROFLUIDIC APPARATUS FOR WIDE AREA MICROARRAYS - A microfluidic device that includes: a) a fluid inlet having a semi-circular groove and b) a flow chamber comprising an inner wall having an inlet end. The fluid inlet is in communication with the flow chamber. The inner wall at the inlet end is curved and has a radius similar to the radius of semi-circular groove. | 03-05-2009 |
20090060787 | METHOD FOR UNIFORM ANALYTE FLUID DELIVERY TO MICROARRAYS - A method of chemical analysis that includes: a) introducing an analyte fluid having a flow to a surface of a sample chip through a microfluidic device comprising i) a fluid inlet having a semi-circular groove and ii) a flow chamber comprising an inner wall having an inlet end, where the fluid inlet is in communication with the flow chamber and where the inner wall at the inlet end is curved and has a radius similar to the radius of semi-circular groove; b) maintaining the flow of the analyte fluid such that the analyte fluid forms a pattern on the surface of the sample chip, the pattern approximating the semi-circular groove; c) maintaining the flow of the analyte fluid so that a linear fluid front forms on the surface of the sample chip at the inlet end; and d) maintaining the flow so that the linear fluid front moves along the surface of the sample chip. | 03-05-2009 |
20090060788 | Microfluidic component with a channel filled with nanotubes and method for its production - A microfluidic component comprises at least one channel ( | 03-05-2009 |
20090060789 | Sensor assembly - The invention relates to a sensor assembly comprising a first electronic wiring substrate having a first and a second surface and at least one analyte sensor formed on the first surface thereof, the at least one analyte sensor being connected with one or more electrical contact points, a second electronic wiring substrate having a first and a second surface and at least one analyte sensor formed on the first surface part thereof, the at least one analyte sensor being connected with one or more electrical contact points, and a spacer having a through-going recess with a first and a second opening, wherein the first substrate, the second substrate and the spacer are arranged in a layered structure, where the first surface of the first substrate closes the first opening of the spacer and the first surface of the second substrate closes the second opening of the spacer, thereby forming a measuring cell which is faced by at least one sensor from each of the substrates. | 03-05-2009 |
20090060790 | SENSOR FOR DETECTING SUBSTANCE IN LIQUID - A sensor for detecting a substance in liquid includes a sensing circuit including a sensing surface acoustic wave (SAW) element in which a reaction film to react with a substance in liquid, a reference circuit including a reference SAW element including an IDT and not including a reaction film, a first signal source driving the sensing circuit, a second signal source driving the reference circuit and being independent of the first signal source, and a differential circuit arranged to output a differential output between an output of the sensing circuit and an output of the reference circuit. The frequency of a first frequency signal output from the first signal source is different from the frequency of a second frequency signal output from the second signal source, thereby making a driving frequency for the sensing SAW element and a driving frequency for the reference SAW element substantially the same as or different from one another. | 03-05-2009 |
20090060791 | MICROCHANNEL CHIP AND METHOD FOR MANUFACTURING SUCH CHIP - The present invention provides a microchannel chip having microchannels fabricated without using an original such as a mold. The microchannel chip of the present invention comprises at least an upper substrate and a lower substrate, the upper substrate and the lower substrate being bonded together, characterized in that at least one non-bonding thin-film layer is formed on the bonding side of at least one substrate and that opposite ends of the non-bonding thin-film layer are each connected to a port open to the atmosphere. When a positive pressure is applied through one port, the area that corresponds to the non-bonding thin-film layer inflates to create a gap that can function as a microchannel, with the result that a liquid and/or a gas can be transferred from one port to the other. | 03-05-2009 |
20090068063 | AUTOMATIC ANALYZER - An automatic analyzer including a rinse mechanism is adapted so that a suction member for suctioning up rinse water is reliably inserted into a reaction cuvette. | 03-12-2009 |
20090074615 | MICROFLUIDIC MODULE INCLUDING AN ADHESIVELESS SELF-BONDING REBONDABLE POLYIMIDE - A microfluidic module that comprises an adhesiveless self-bonding rebondable polyimide film. | 03-19-2009 |
20090074616 | SPECIMEN ANALYZER AND LIQUID SUCTION ASSEMBLY - A specimen analyzer, comprising: a liquid suction assembly; a measurement section for measuring a specimen; and a connection section for connecting the liquid suction assembly and the measurement section, wherein the liquid suction assembly comprises: a suction nozzle, disposed inside a liquid container storing liquid used for measurement of the specimen, for sucking the liquid in the liquid container; a fluid volume sensor for detecting whether a predetermined volume of the liquid remains in the liquid container; and a notice section for notifying that the liquid in the liquid container is smaller than the predetermined volume, is disclosed. A liquid suction assembly is also disclosed. | 03-19-2009 |
20090074617 | SENSOR CARTRIDGE, SENSOR FEEDER, AND MEASURING INSTRUMENT - A sensor cartridge ( | 03-19-2009 |
20090074618 | Sample analyzer - A sample analyzer is disclosed that comprises: an analysis section for analyzing a sample by using a reagent; an information receiver for receiving an input of information regarding the reagent; a determination section for determining, whether or not the reagent satisfies a condition to determine that the reagent is a genuine product, based on the information received by the information receiver; and a controller for controlling an operation of the sample analyzer based on a result of the determination by the determination section. | 03-19-2009 |
20090087345 | DISK FOR LIQUID SAMPLE ANALYSIS - A disk for liquid sample analysis that has means for detecting any chemical reaction between liquid sample and reagent, and that among others, enhances the accuracy of detecting of components of the liquid sample through “rapidly and homogeneously” dissolving of a solid reagent in the liquid sample. In particular, there is provided a disk for liquid sample analysis comprising one or two or more chambers created in a disk-shaped member and a flow channel for inter-chamber connection, wherein a porous body is disposed in at least one of the chambers, and wherein the porous body bears a reagent capable of reacting with a specified component of the liquid sample. On this disk for liquid sample analysis, the liquid sample can be moved by centrifugal force by rotation and capillary force occurring in the chambers and flow channel. | 04-02-2009 |
20090098018 | TEST DEVICE FOR DETERMINING AN ANALYTE CONCENTRATION - A test device for determining the concentration of at least one analyte in a sample using a element is proposed. The test device can be used particularly for glucose measurement, in particular blood glucose measurement, cholesterol measurement and/or coagulation measurement. The test device according to the invention comprises a housing with a closed state and an opened state, and a storage device for receiving at least one test element. The at least one test element is typically designed as a strip-shaped test element, and the storage device typically comprises a magazine. The magazine comprises a plurality of cavities, and the test elements are received substantially parallel to one another in the cavities. A measuring device and a dispensing device are also provided. The dispensing device comprises means for conveying the at least one test element from at least one storage position of the storage device during opening of the housing. | 04-16-2009 |
20090098019 | BIOSENSOR APPARATUS FOR DETECTION OF THERMAL FLOW - In general terms the biosensor apparatus according to the invention comprises a housing ( | 04-16-2009 |
20090098020 | Binding Assay - A binding assay product ( | 04-16-2009 |
20090098021 | Filter with memory, communication and concentration sensor - The present invention describes a system and method for accurately measuring the concentration of a substance within a filter housing. A concentration sensor and a communications device are coupled so as to be able to measure and transmit the concentration of a particular substance within the filter housing while in use. This system can comprise a single component, integrating both the communication device and the concentration sensor. Alternatively, the system can comprise separate sensor and transmitter components, in communication with one another. In yet another embodiment, a storage element can be added to the system, thereby allowing the device to store a set of concentration values. The use of this device is beneficial to many applications. For example, the ability to read concentration values in situ allows integrity tests to be performed without additional equipment. | 04-16-2009 |
20090104076 | SAMPLE PREPARATION CARTRIDGE AND SYSTEM - A modular specimen preparation cartridge with a tubular body with the interior segmented by pressure sensitive membranes that will rupture or open when exposed to a threshold pressure forming a sequence of chambers. Bladders or capsules filled with reagents or other fluids that will release the contents of the capsules under applied pressure are contained in the chambers. Filters, temperature control elements, diagnostic test strips, or catalysts may also be in the chambers. The cartridge may be adapted to virtually any sample preparation and/or analysis protocols or to sample type. The cartridge may also be modular and capable of being coupled to other cartridges or storage containers. In one embodiment, the tubular body is compressible and external pressure causes the capsules to rupture releasing the contents into the chamber. In another embodiment, pressure is applied to membranes and reagent capsules through the use of a plunger advancing though the center of the body. | 04-23-2009 |
20090110599 | METHODS OF OPERATING FILM SURFACE REACTORS AND REACTORS EMPLOYING SUCH METHODS - In new methods of operating surface reactors, and new reactors employing such methods, the reactor comprises a cylindrical rotor and a cylindrical stator coaxial with one another with respective cylindrical faces forming an annular reaction chamber between them, the chamber being filled with air or inert gas constituting a shear transmitting fluid. The volume of the reactants, one of which at least must be in liquid state, fed into the chamber is only such that they will immediately be spread out under centrifugal force on the stator surface by the shear transmitting fluid in the form of a film of thickness not more than 150 micrometers, preferably not more than 120 micrometers, and more preferably less than 100 micrometers. The rotor is rotated at high speed, usually about 30,00 to 80,000 rpm, and at these speeds molecular clusters which normally slow down one on one molecular encounters between the reactant molecules, are disrupted by the high shear to facilitate forced, uniform molecular interdiffusion, so that the molecules more aggressively and quickly interact with one another with considerably increased rates of reaction, e.g 100 to 1,000 times increase. This use of an intermediate shear transmitting gaseous fluid gives flexibility in the radial dimension of the reaction chamber, which can be 1 mm or larger, avoiding the need for a reaction chamber of radial dimension corresponding to the desired film thickness and its attendant difficulties, due for example to differential expansion of the rotor and stator with rotation and temperature changes. | 04-30-2009 |
20090110600 | METHODS OF OPERATING FILM SURFACE REACTORS AND REACTORS EMPLOYING SUCH METHODS - In new methods of operating surface reactors, and new reactors employing such methods, the reactor comprises a helical reaction chamber formed as a coil surrounding a tubular support, or a groove machined in a cylindrical body. The passage is supplied with a high velocity flow of air or inert gas constituting a shear transmitting fluid that immediately spreads the reactants, one of which at least must be in liquid state, as they are fed into the chamber against the radially outermost wall of the chamber into a film of thickness not more than 150 micrometers, preferably not more than 120 micrometers, and more preferably less than 100 micrometers. The fluid is supplied at velocities of between 1 and 100 meters per second, preferably between 6 and 20 meters per second. At these speeds and corresponding centrifugal force, molecular clusters, which normally inhibit one on one molecular diffusion reaction between the reactant molecules, are disrupted by the highly sheared fluid to facilitate forced molecular interdiffusion, so that the molecules more aggressively and quickly interact with one another with considerably increased rates of reaction, e.g. 100 to 1,000 times increase. This use of an intermediate shear transmitting fluid traveling at high velocity in a circular path gives flexibility in the radial dimension of the reaction chamber, which can be as large as 10 mm radially and 6 mm longitudinally and provides one open surface of the sheared film of the reagents. | 04-30-2009 |
20090110601 | Molecularly imprinted polymers for detection in lateral flow devices - Devices, methods and kits for rapid and simple determination of target molecules, including small molecules, polypeptides, proteins, cells and infectious disease agents in liquid samples that are capable of real-time measurement of these entities in fluid samples that are highly selective, highly sensitive, simple to operate, low cost, and portable. The devices, methods and kits also provide, in at least some embodiments, the use of MIPs in a flow through or lateral flow device. | 04-30-2009 |
20090123336 | MICROFLUIDIC CHIPS FOR RAPID MULTIPLEX ELISA - A microfluidic chip comprises a substrate and a channel or multiple channels in the substrate. Each channel includes a tortuous path section or multiple tortuous path sections. A receptor for the detection of an analyte can be immobilized in a tortuous path section, for example by adsorption. Different receptors can be immobilized in different tortuous path sections of each channel or in different channels for simultaneous detection of multiple analytes. The chip is especially useful for running immunoassays, particularly ELISA. | 05-14-2009 |
20090129980 | Multi-Channel Flow Cells - A multi-channel flow cell can allow for reduced cross-contamination in sample loading and the ability to observe activity within the flow cell once the channels are loaded. A multi-channel flow cell includes a plurality of independently-addressable channels sandwiched between a two substrates. Each of the channels can be coated with a layer that facilitates support-binding of an analyte. Each of the channels terminates on one end in an inlet and on the other end in an outlet. A loading block having inlet ports that match the inlets of the channels can be mated to the inlets of the channels, and an outlet block can be mated to the outlets of the channels. Analytes can be introduced into the channels via the inlet ports of the loading block and are pulled through the channels by capillary action or by vacuum. Once analyte has been introduced into each of the channels, the loading and outlet blocks can be removed and the device turned over Such a flow cell can be used for streamlining the process of reaction and interrogation of biochemical assays at the microfluidic level. Reagents can be introduced into each of the channels of the flow cell for chemical reactions therein, excess reagent being washed out through the channel outlets. Observation of optically-detectable moieties is then conducted. With such a flow cell optical labels associated with incorporation in a sequencing-by-synthesis reaction can be observed. | 05-21-2009 |
20090129981 | MICROFLUIDIC DEVICE - A microfluidic device includes a microfluidic chip and an ultrasonic stator. A holding portion is formed at the ultrasonic stator to hold the microfluidic chip. The microfluidic chip is formed of a substrate with a very small channel, and a valve is provided movably in the channel. The cross section of an upstream portion of the channel is larger than that of a downstream portion. When the valve is moved to the downstream side, the valve closes and decouples the downstream portion of the channel. When the valve is moved to the upstream side, the upstream and downstream portions of the channel are coupled. The valve is moved by a traveling wave generated by the ultrasonic stator, and the traveling wave is transmitted to the substrate via the holding portion. | 05-21-2009 |
20090142229 | Blood Cell Barrier for a Lateral Flow Device - A lateral flow device for analyzing a whole blood sample is provided. More specifically, the lateral flow device contains a porous membrane that defines a barrier zone for separating red blood cells from blood plasma (includes plasma in which clotting factors haven been removed), which may then flow to a subsequent detection zone for analysis. The barrier zone is formed from a blood cell barrier composition that includes an unsaturated aliphatic fatty acid or an ester thereof. Without intending to be limited by theory, the present inventors believe such unsaturated aliphatic fatty acid molecules undergo autoxidation in the presence of air and hemoglobin to release peroxides (e.g., hydrogen peroxide) via oxidative saturation of double bonds. In turn, the released peroxides are believed to induce the formation of echinocytes or crenated blood cells. The crenated red blood cells are distorted in shape and less flexible and malleable than normal red blood cells, making them less able to penetrate into the pores of the porous membrane of the lateral flow device. Consequently, the stiffer, less flexible cells cannot move easily into the porous and become trapped at the surface of the membrane, while the liquid components of the sample flow and penetrate through the membrane to the detection zone for analysis. | 06-04-2009 |
20090142230 | ASSEMBLY COMPRISING J AGGREGATES - The present invention relates to the realization of particular supramolecular assemblies of dyes, in particular cyanines, called J aggregates. The invention concerns an assembly made up of
| 06-04-2009 |
20090142231 | AUTOMATIC ANALYZER - The automatic analyzer stores: a predetermined period from the opening of a reagent vessel to the deterioration of the reagent; a reagent production lot number, reagent vessel unsealing time, and reagent expiration date as reagent information kept on a reagent-set-by-set basis; and relevant calibration curve factor information. The automatic analyzer judges whether a calibration curve factor for a reagent set is applicable or not to another reagent set of the analyzer with the same production number based on the predetermined period from the reagent vessel unsealing time and on the reagent expiration date. | 06-04-2009 |
20090155124 | COLLECTION AND ASSAY DEVICE FOR BIOLOGICAL FLUID - A device for collecting and analyzing a biological fluid is provided. The device contains a sample collecting section having at least one collection pad for collecting a sample of the biological fluid, a sample accommodating section operatively engageable with the sample collecting section for extracting and accommodating the sampled collected by the sample collecting section, a sample analyzing section, disposed within the sample accommodating section and having a sample analyzing means in fluid communication with the sample extracted and accommodated within the sample accommodating section. | 06-18-2009 |
20090162248 | Compact Foldable Meter - A foldable instrument ( | 06-25-2009 |
20090169427 | CONTROLLED FLUID DELIVERY IN A MICROELECTRONIC PACKAGE - A microelectronic package includes a die which may include MEMS and CMOS circuitry for analyzing a fluid. A defined path is provided for channeling fluid to the die. Rather than patterning depressions or physical channels in the package substrate, the defined paths comprise coatings that may channel the flow of liquids to the die for biological sensor type applications. The defined paths may comprise a wetting coating that has an affinity to fluids. Similarly, the defined paths may comprise a dewetting coating the tend to repel fluid surrounding the paths. | 07-02-2009 |
20090169428 | Flow Cell With Piezoelectric Ultrasonic Transducer - A flow cell has a cavity ( | 07-02-2009 |
20090169429 | EXCHANGEABLE CONSUMABLE WITH INTEGRATED AIR FILTER - The invention concerns an analyzer, typically for analyzing body fluids, which has one or several exchangeable cassettes (consumables) that contain operating liquids, operating materials and/or consumables and can be inserted into corresponding holders of the analyzer, wherein the analyzer has a system for exchanging ambient air which has a filter unit on the inlet side of the analyzer to filter the ambient air that needs to be exchanged. The filter unit is integrated into at least one of the exchangeable cassettes in order to minimize the amount of maintenance for the analyzer. | 07-02-2009 |
20090175764 | Measurement Device with At Least One Sensor - A measurement device has at least one sensor for detecting a parameter, a data storage unit, and a power supply for said sensor and data storage unit. In addition to the first sensor, the measurement device has at least one second sensor connected to the power supply and to the data storage unit. The second sensor is provided for detecting a physical quantity acting on the first sensor and is capable of permanently altering the measurement characteristic of the first sensor. An evaluator functions coactively with the second sensor and the data storage unit so that the permanent alteration of the measurement characteristic of the first sensor is recordable as a function of the measurement signal of the second sensor. | 07-09-2009 |
20090175765 | Surfaces Resistant to Non-Specific Protein Adsorption and Methods of Producing the Same - A method of preventing non-specific adsorption of proteins onto a surface can include providing a substrate that has a surface on which surface groups are attached. A solution can be applied to the surface that includes a protective reagent having a terminal functional group exhibiting a dipole moment. A monolayer comprising the protective reagent is assembled on the surface by reacting the protective reagent with the surface groups, thereby creating a protected surface. The protective reagent alone is sufficient to confer to the protected surface an increased resistance to adsorption of proteins. | 07-09-2009 |
20090185955 | MICROFLUIDIC DEVICE FOR MOLECULAR DIAGNOSTIC APPLICATIONS - The present invention relates to a micro fluidic device for analysis of a fluid sample, especially for molecular diagnostics applications, comprising: —a substrate having a surface with at least one micro channel structure thereon; —at least one detecting, controlling and/or processing element; —at least one reception chamber for receiving the fluid sample, wherein the reception chamber is formable between a membrane and the substrate, wherein the reception chamber is fluently connected with at least one micro channel; —at least one membrane, wherein the membrane covers the upper surface of at least one micro channel structure arranged on said substrate leakage proof, whereby movement of said membrane causes a pump action on fluid located in said reception chamber in said micro channel and/or causes a valve action on fluid directed through said micro channel; and—at least one device for actuating the movement of the membrane, comprising pressure and/or vacuum generating means. | 07-23-2009 |
20090191096 | Microchemical Chip - A microchemical chip of the present invention has a base composed of a ceramic and a light-transmitting member. The base composed of a ceramic is provided with a channel, a fluid supplying section disposed on the upstream side of the channel, a fluid reacting section disposed on the downstream side of the fluid supplying section, and a detecting section disposed on the downstream side of the fluid reacting section. The light-transmitting member is disposed so as to cover the detecting section of the base. With this configuration, the channel is formed in the base composed of a ceramic excellent in chemical resistance and heat resistance, thereby enabling reliability to be improved. Since the light-transmitting member is disposed so as to cover the detecting section, the reaction product can be inspected by an optical technique, for example, thereby enabling detection accuracy to be improved. | 07-30-2009 |
20090202391 | MICRO PASSAGE CHIP AND FLUID TRANSFERRING METHOD - There is provided by the present invention a novel micro passage chip having such a structure that a fluid can be transferred without using a physical or mechanical squeezing means that is applied from above the substrate of the micro passage chip. The micro passage chip of the present invention comprises at least a first substrate, a second substrate, and an intermediate substrate interposed between the first substrate and the second substrate and is characterized in that a first non-adhesive thin-film layer is formed on at least one of the mating sides of the first substrate and the intermediate substrate and at least one port for fluids that is in contact with the first non-adhesive thin-film layer and which is open to the outer surface of the first substrate is provided in any position on the first non-adhesive thin-film layer, and that at least a portion of a second non-adhesive thin-film layer whose length is either the same as or different from that of the first non-adhesive thin-film layer is formed on at least one of the mating sides of the second substrate and the intermediate substrate such that it lies either above or under the first non-adhesive thin-film layer, with the intermediate substrate lying in between, and a pressurizing port that is in contact with the second non-adhesive thin-film layer and which is open to the outer surface of the first or the second substrate is provided in at least one area on the second non-adhesive thin-film layer. | 08-13-2009 |
20090208372 | SHEATH FLOW DEVICE AND METHOD - A sheath flow system having a channel with at least one fluid transporting structure located in the top and bottom surfaces situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. | 08-20-2009 |
20090208373 | Captive evaporation cover for dissolution systems - A vessel includes a cylindrical section, a bottom section, a flange, and a shoulder between the flange and the bottom section. The shoulder extends from an outside vessel surface and is concentric with an inside vessel surface relative to a central axis of the vessel. The vessel may be mounted at a dissolution test apparatus by inserting the vessel in an aperture such that the shoulder abuts an inside edge defining the vessel plate. The concentric shoulder enables the vessel to be centered in the aperture, or relative to an instrument inserted in the vessel along the central axis. | 08-20-2009 |
20090208374 | Novel silane compounds carrying a hydrazone or diazo functional group in order to functionalize solid supports and immobilize biological molecules on these supports - The invention relates to novel silane compounds corresponding to the following formula (I): | 08-20-2009 |
20090208375 | Method for Improving a Polymerization Reaction by Taking Out and Analysing a Sample - The invention relates to a device for taking out and analysing a sample from a polymerisation reactor comprising one or more sample conduits ( | 08-20-2009 |
20090220380 | Wireless electronic monitor for a container such as an aquarium and the like - A wireless electronic monitor for a container such as an aquarium is described. The apparatus comprises a sense and transmit assembly (STA) | 09-03-2009 |
20090220381 | IMAGEWISE PATTERNING OF FILMS AND DEVICES COMPRISING THE SAME - The present invention is directed, at least in part, to methods for imagewise patterning of a surface. Such patterned surfaces can be used, e.g., in microfluidic devices. Accordingly, the present invention is also directed, at least in part, to nanopatterned devices which include a microchannel structure and methods for forming such devices. | 09-03-2009 |
20090220382 | NANO-GETTER DEVICE - A nano-structured device for detecting biological analytes, chemical, analytes, cancer and other physiological conditions, includes a carrier substrate, a transducer film disposed over a surface of the carrier substrate, and a dendrimer structure tethered to the transducer film. The transducer film generates a first signal in response to a mechanical stress applied thereto. The first signal indicates the detection of the biological analyte, chemical analyte, cancer or other physiological condition. The dendrimer structure includes a plurality of receptors for binding the biological analyte, the chemical analyte, or one or more biomarkers indicative of cancer or other physiological conditions to the dendrimer structure. The dendrimer structure applies the mechanical stress to the transducer film, which is proportional to the strain induced into the dendrimer by the biological analyte, the chemical analyte, or one or more biomarkers indicative of cancer or other physiological condition binding to the receptors, the mechanical stress causing the transducer film to generate the first signal indicating the detection of the biological analyte, the chemical analyte, or one or more biomarkers indicative of cancer or other physiological condition. | 09-03-2009 |
20090220383 | AUTOMATIC ANALYZER - Disclosed herein is an automatic analyzer that can eliminate the generation of air bubbles of dissolved gas in a liquid circulating in a thermostat bath enabling stable photometry. | 09-03-2009 |
20090238722 | Pressure-Reinforced Fluidic Chip - A fluidic chip device adapted for processing a fluidic sample, the fluidic chip device comprising a substrate comprising a fluidic conduit for conducting the fluidic sample under pressure, and two reinforcing structures between which the substrate is arranged, wherein the two reinforcing structures are connected to one another to reinforce pressure resistance of the substrate. | 09-24-2009 |
20090238723 | Multi-modal particle detector - Systems, methods and computer program products for the multi-modal detection of particles are described herein. An embodiment of the present invention is a particle detector that includes a first chamber wherein analyte particles are subjected to a first particle detection mechanism, and a second chamber coupled to the first chamber, wherein the analyte particles are subjected to a second particle detection mechanism, and wherein the detection characteristics of second particle detection mechanism are orthogonal to detection characteristics of the first particle detection mechanism. According to another embodiment, the present invention is a particle detection method including the steps of detecting presence of at least one predetermined particle type in an analyte particle sample using a first particle detection mechanism, and confirming the presence of the predetermined particle type in the analyte particle sample using a second particle detection mechanism, wherein detection characteristics of the second particle detection mechanism are orthogonal to detection characteristics of the first detection mechanism. | 09-24-2009 |
20090238724 | DISC FOR ANALYZING SAMPLE - It is an object of the present invention to provide a disc for analyzing a fluid sample, which can analyze the fluid sample with accuracy by having the fluid sample react quickly and uniformly with the solid reagent held in the chamber. The disc has a chamber is defined by a gap formed with at least two opening, and defined by a spacer intervening between an upper substrate and a lower substrate, the upper substrate having a convex section, the lower substrate having a concave section, the reagent being attached to the concave section of the lower substrate. | 09-24-2009 |
20090257917 | Sensor Chip and Sensor Chip Production Method - It is intended to provide a sensor chip which has a small size and is easily produced and capable of determining quantities of at least two components of multiple samples rapidly, conveniently, and correctly as well as to provide a production method capable of producing the sensor chip easily and with high productivity. | 10-15-2009 |
20090257918 | REACTION CUVETTE FOR AUTOMATIC ANALYZER AND METHOD OF SURFACE TREATMENT FOR REACTION CUVETTE - The present invention provides reaction cells capable of maintaining stable analytical performance by preventing bubble adhesion and reducing sample carryover even if the amount of sample liquid for a single test is further reduced in the future. The invention further provides an automatic analyzer that uses the reaction cells and a method for enhancing the hydrophilicity of the inner surfaces of the reaction cells. According to the invention, a reaction cell has a first electrode inserted thereinto and a second electrode disposed on the bottom side of the reaction cell. A voltage is applied between the first electrode and the second electrode to cause electric discharge between the electrodes. This allows for enhancing only the hydrophilicity of the bottom inner surface and the four bottom corners of the reaction cell to which large bubbles adhere easily. | 10-15-2009 |
20090263281 | AUTOMATIC ANALYZER - An automatic analyzer is capable of recording contents of a sample subjected to a special treatment to take for an unusual condition to ensure traceability of the sample. The automatic analyzer has functions to easily perform a process for a series of operations including the special treatment, a request for a re-measurement after the special treatment, and confirmation of the result of the re-measurement. The automatic analyzer has a database dedicated for a sample accompanied by an unusual condition and records contents of the special treatment in the database. The automatic analyzer has a dedicated re-measurement request screen, a dedicated measurement result screen and a dedicated special treatment trace screen. The automatic analyzer has a function of guiding a method for coping with each unusual condition. | 10-22-2009 |
20090263282 | Microchip - A microchip including a fluid circuit formed by a groove of a first substrate and a surface of a second substrate is provided. The fluid circuit includes a fluid retaining reservoir for containing a fluid. The fluid retaining reservoir includes a fluid outlet or outflow channel for allowing the fluid to flow out, and a partition dividing the fluid retaining reservoir into a first region including a fluid inlet for injecting a fluid into the fluid retaining reservoir and a second region including the fluid outlet or outflow channel. The partition includes at least one communication gate for allowing communication between the first region and the second region. | 10-22-2009 |
20090269242 | ANALYZER - An analyzer includes a management unit that manages initiation timings of a calibration analysis process, in which a calibrator is analyzed, and a blank analysis process, in which a blank sample is used, independently for each of the analytical items. The management unit performs at least the blank analysis process before an expiration date for managing accuracy of a result of the blank analysis and when a reagent is supplied, and the management unit performs the calibration analysis process before an expiration date for managing accuracy of a result of the calibration analysis and when the reagent is supplied. | 10-29-2009 |
20090285719 | Compressible Transparent Sealing for Open Microplates - An apparatus for sealing a microplate, wherein the apparatus comprises a microplate having a first surface and an opposing second surface. A plurality of wells is formed in the first surface of the microplate, wherein each of the plurality of wells is sized to receive an assay therein. A sealing cover is disposed over the microplate adjacent the plurality of wells and is compliant to accommodate variations between the sealing cover and the microplate and/or distribute loads evenly therebetween. | 11-19-2009 |
20090291024 | FORMATION OF HIGHLY POROUS GAS-SENSING LAYERS BY DEPOSITION OF NANOPARTICLES PRODUCED BY FLAME SPRAY PYROLYSIS - The invention relates to a method of producing a gas sensor comprising the steps of
| 11-26-2009 |
20090291025 | Microchip And Method Of Using The Same - A microchip is provided, which includes: a second substrate, and a first substrate having a groove on its surface, stacked on the second substrate; and a fluid circuit composed of a cavity defined by the groove and a surface of the second substrate on the side of the first substrate; wherein the fluid circuit includes a mixing portion as a chamber for mixing two or more liquids; and at least a part of a wall forming the mixing portion consists of a linearly extending first wall and a second wall linearly extending from an end of the first wall. A method of using the microchip is also provided. | 11-26-2009 |
20090304549 | MICROFABRICATED DEVICES WITH COATED OR MODIFIED SURFACE AND METHOD OF MAKING SAME - A microfabricated device or component thereof, such as microfluidics or nanofluidics device having a uniform non-wetting or non-absorbing polymeric coating or surface modification formed on a surface thereof by ionisation or activation technology such as plasma processing, to produce a surface energy of less than 15 mNm | 12-10-2009 |
20090304550 | ANALYTICAL TOOL - The present invention relates to an analytical tool ( | 12-10-2009 |
20090317298 | Microfluidic System Comprising Microfluidic Pump, Mixer or Valve - A microfluidic system. The system comprises: (A) a microfluidics platform comprising: a compliant body having a microfluidic channel defined therein; an elongate chamber defined by a section of the microfluidic channel, the chamber having a membrane wall defining part of an outer surface of the body; and a plurality of compression members spaced apart along the membrane wall, each compression member being configured for pinching a respective part of the membrane wall against an opposed wall of the chamber; and (B) a MEMS integrated circuit bonded to the outer surface of the body, the MEMS integrated circuit comprising: a plurality of moveable fingers, each finger engaged with a respective compression member, each finger being configured to urge the respective compression member between a closed position in which the respective part of the membrane wall is sealingly pinched against the opposed wall, and an open position in which the respective part of the membrane wall is disengaged from the opposed wall; a plurality of thermal bend actuators, each associated with a respective finger for controlling movement of the respective finger, and control circuitry for controlling actuation of the actuators. | 12-24-2009 |
20100021344 | BETA-PEPTIDE LYOTROPIC LIQUID CRYSTALS AND METHODS OF MANUFACTURE AND USE THEREOF - The present invention provides materials and methods that make liquid crystal phases accessible with relatively short β-peptides in aqueous solvents. | 01-28-2010 |
20100021345 | Modular Microfluidic System - There is described a modular microfluidic system with the following features: Modules are arranged next to each other in a row. Every module has a microfluidic part which rests on a contact surface of the module in a locally limited area and is forced against the same by means of a fastening element. The microfluidic part comprises a fluid channel system with fluid connections that are arranged on the top surface of the microfluidic part in edge areas relative to the adjoining microfluidic parts. The fluid connections of adjoining microfluidic parts are interlinked by respective connecting channels in a connecting part bridging the microfluidic parts, said connecting part resting on the microfluidic parts in the edge areas. A clamping part rests against the lower surfaces of the adjoining microfluidic parts and is connected to the connecting part via an additional fastening element in the area between the microfluidic parts. | 01-28-2010 |
20100028204 | DEVICE, SYSTEM AND METHOD FOR PROCESSING A SAMPLE - A device for the processing of a sample comprises a location apparatus, a processing chamber for receiving the sample and a plurality of reagent chambers. The reagent chambers have openings defined in the location apparatus. The processing chamber is movable relative to the reagent chambers to enable sequential communication with each reagent chamber in turn. | 02-04-2010 |
20100028205 | MICRO-FLUIDIC DEVICE FOR THE USE IN BIOCHIPS OR BIOSYSTEMS - The Invention concerns to a micro-fluidic device for the use in biochip or bio-system, wherein an 2 dimensional matrix array of temperature sensitive Poly-MEM actuators ( | 02-04-2010 |
20100028206 | MICROCHIP AND METHOD OF MANUFACTURING MICROCHIP - A microchip having: two flow path substrates having flow paths in a shape of a groove formed on one side of each substrate thereof; and a communication hole substrate on which a communication hole is formed to communicate the flow paths of the two substrates each other; wherein the two substrates are bonded in a way that the surfaces, on which the flow paths in the shape of the groove formed, face each other, having the communication hole substrate therebetween. | 02-04-2010 |
20100047129 | FECAL SAMPLING DEVICE AND METHOD - A device for testing a specimen comprising a first panel, a metering aperture structure having a plurality of metering apertures formed therein for receiving the specimen therethrough, a second panel opposite the first panel, a sheet disposed between the first and second panels, the sheet including a test area aligned with the plurality of metering apertures, a spacer element disposed between the first panel and the sheet, wherein the metering aperture structure is spaced away from the test area thereby improving readability of the testing. A method of manufacturing a specimen testing device is also disclosed. | 02-25-2010 |
20100047130 | Lab-On-Cd Systems With Magnetically Actuated Micro Check Valves And/Or Magnetic Immobilization - The present invention provides lab-on-CD (LoCD) systems for conducting chemical and biological reactions. One of the LoCD systems comprises a microfluidic CD with at least one magnetically actuated micro check valve, said microfluidic CD having at least one sample reservoir, at least one reaction chamber, and at least one microfluidic channel connecting the at least one sample reservoir and the at least one reaction chamber; wherein the at least one magnetically actuated micro check valve is positioned to control the microfluidic flow in the at least one microfluidic channel; and a supporting CD with at least one magnetic element for providing a magnetic force; thereby when the microfluidic CD and the supporting CD are assembled into the LoCD system, the at least one magnetic element can move the at least magnetically actuated micro check valve so as to control the microfluidic flow in the at least one microfluidic channel. | 02-25-2010 |
20100054995 | METHOD FOR ALIGNING CARBON NANOTUBES IN MICROFLUIDIC CHANNEL - A method includes aligning nanotubes in a microfluidic channel including supplying nanotubes to the microfluidic channel; forming at least one interface in the channel; and applying a pressure to the microfluidic channel to control orientation of the nanotubes. A microfluidic device includes a silicon chip having a outer surface further including an upper surface and a lower surface; an upper wafer attached to the upper surface of the silicon chip; and a lower wafer attached to the lower surface of the silicon chip; wherein: the silicon chip, upper wafer, and lower wafer form a microfluidic channel; one or more nanotubes are aligned on the silicon chip according to the method; and the outer surface includes probe molecules. | 03-04-2010 |
20100054996 | MICROCHIP FOR PROTEIN FIXATION - Disclosed is a microchip for protein fixation, which fixes a specific protein, such as albumin, immunoglobulin, transferrin, or keratin, to beads so as to detect a micro amount of proteins during a micro analysis process, such as Liquid Chromatography/Mass Spectrometry (LC/MS) or Matrix Assisted Laser Desorption/Ionization Time Of Flight Mass Spectrometry (MALDI-TOF/MS). The microchip for protein fixation reduces the amount of a sample, shortens a reaction time, heightens the reliability in results, and simplifies a working process. For this reason, the beads provided with an antibody attached thereto are contained in a chamber of the microchip having a stratified structure using an organic polymer, i.e., dimethylsiloxane (PDMS), the pressure of a micro amount of a sample passing through the chamber is uniformly distributed onto all the beads, and the micro amount of the sample passes through the beads having a large surface area and is smoothly discharged to the outside at the optimum speed so as to effectively fix the specific protein. Thus, the microchip for protein fixation optimizes the speed of the sample passing through the microchip, and increases an efficiency of fixing the specific protein to the antibody due to the sufficient surface area of the fine-sized beads, thereby obtaining a rapid reaction result. | 03-04-2010 |
20100054997 | AUTOMATIC ANALYZING APPARATUS - In an automatic analyzing apparatus that analyzes a mixture of a tested sample and a reagent, by selecting the reagent, acquiring cross-check information unique to the kind of the selected reagent, inputting input information for acquiring permission for input of data including an analysis parameter of the selected reagent, and cross-checking the cross-check information and the input information, it is determined whether to permit the input of the data. In a case that it is determined to permit the input of the data, the input of the data is accepted and, based on the analysis parameter reflecting the inputted data, the mixture of the tested sample and the reagent is measured and analysis data is generated. | 03-04-2010 |
20100061891 | Flow analysis system capable of quantitatively or semi-quantitatively determining element in sample - A flow analysis system or flow injection analysis system, providing a high detection sensitivity even when metallic elements contained in a sample are of extreme trace in amount, wherein a sealed vessel in which a reagent solution is encapsulated is composed of a material having an oxygen permeability of 10 fmol/m | 03-11-2010 |
20100061892 | MICROFLUIDIC DEVICE HAVING AN ARRAY OF SPOTS - A microfluidic spotting device has a first substrate patterned with an array of spots, a second substrate attached directly or indirectly to the first substrate, and channels formed at least partly in at least one of the first substrate and the second substrate, each channel having an inlet channel and an outlet channel. | 03-11-2010 |
20100068097 | FLUID-CONTAINING POUCHES WITH REDUCED GAS EXCHANGE AND METHODS FOR MAKING SAME - The invention is directed to fluid-containing pouches and to methods for forming fluid-containing pouches. In one embodiment, the invention is to a fluid-containing pouch, comprising first and second opposing sheets, and a fluid (e.g., a calibrant fluid, a reactant fluid or a wash fluid) disposed between the first and second opposing sheets. The first sheet and the second sheet have a substantially liquid and gas impermeable perimeter seal. The sheets may be sealed, for example, by one or more of heat crimping, pressure crimping, heat and pressure crimping, ultrasonic welding, metal-to-metal welding or laser welding. Fluid-containing pouches sealed according to the disclosed methods and apparatuses show substantially improvement in terms of reduced gas exchange, notably CO | 03-18-2010 |
20100068098 | MICROFLUIDIC DEVICES AND METHODS FOR MULTIPLE ANALYTE DETECTION - The invention is directed to microfluidic devices comprising at least two processing channels, wherein each of the processing channels comprises an inlet, an outlet, and a high-flow-resistant and hydrophilic conduit; a distributing channel, wherein the distributing channel comprises an upstream end and a downstream end, and is in fluid communication with each inlet of the processing channels via the high-flow-resistant and hydrophilic conduit; and a flushing channel, wherein the flushing channel comprises an upstream end and a downstream end, and is in fluid communication with each outlet of the processing channels. The invention also provides methods of using the microfluidic devices. | 03-18-2010 |
20100074801 | MICROCHIP AND ANALYZER USING THE SAME - A microchip having an inlet ( | 03-25-2010 |
20100086441 | BEAM RADIATING DEVICE, BIO-CHEMICAL ANALYZER INCLUDING THE BEAM RADIATING DEVICE, AND BIO-CHEMICAL ANALYZING SYSTEM INCLUDING THE BIO-CHEMICAL ANALYZER - Provided are a beam radiating device that is used to operate elements, such as valves, included in a microfluidic device, a bio-chemical analyzer which includes the beam radiating device and is configured to perform various tests by using a bio-sample, and a bio-chemical analyzing system including the bio-chemical analyzer and the microfluidic device. The beam radiating device includes: an energy source which is spaced apart from a target and emits an electromagnetic wave beam; a first pivot unit which pivots the energy source by a first angle on a first pivot axis that does not pass the target; and a second pivot unit which pivots the energy source by a second angle on a second pivot axis that perpendicularly crosses the first pivot axis and does not pass the target. | 04-08-2010 |
20100098585 | Biosensor Package Structure with Micro-Fluidic Channel - A biosensor package structure with a micro-fluidic channel is provided. The biosensor package structure includes a substrate, a biochip, and a cover. The substrate has a first surface, a second surface, and an opening. The biochip is attached on the first surface. A bio-sensing area of the biochip is exposed to the opening of the substrate. The cover is attached on the second surface to cover the opening so as to form a micro-fluidic channel. By implementing the invention, the manufacturing process of the biosensor is simplified and the productivity is increased. | 04-22-2010 |
20100098586 | Propylene Polymers for Lab/Medical Devices - Polymer compositions and articles formed therefrom are described herein. The compositions include a random copolymer and a radiation additive, wherein the random copolymer includes propylene and less than 2 wt. % ethylene and exhibits a melt flow rate of from about 300 to 100 dg/min., the polymer composition exhibits a flexural modulus of from about 160 kpsi to about 200 kpsi and the polymer composition is adapted to produce a polymer article exhibiting low plate out, a haze at 20 mils of no greater than 15%, radiation stability and autoclavability. | 04-22-2010 |
20100104474 | MICRO FLUIDIC DEVICE - The present invention is directed to a micro fluidic device ( | 04-29-2010 |
20100119414 | SYSTEM FOR MEASURING AN ANALYTE CONCENTRATION OF A BODY FLUID SAMPLE - A system is provided for measuring an analyte concentration in a body fluid sample, comprising at least one cartridge that contains consumables for multiple measurements, a data carrier which is affixed to the cartridge and contains calibration information for the consumables contained in the cartridge, a hand-held device that comprises a cartridge reception compartment including a reading facility for receiving a cartridge of this type and for reading its data carrier, a measuring facility for measuring the result of a detection reaction, a processor that is connected to the measuring facility and the reading facility for controlling the measuring facility and for analysis of a measuring signal. As an additional system component, at least one replaceable data storage unit is further provided in which supplementary data is stored. The data storage unit functions in combination with calibration information from the data carrier, wherein the hand-held device comprises an interface for transmission of supplementary data from the replaceable data storage unit to the device, and a consumables identification is stored on the data carrier and used by the processor after insertion of a cartridge to determine whether the consumables of the inserted cartridge, combined with the supplementary data that is available to the processor, renders a reliable measurement of an analyte concentration of a body fluid sample feasible. | 05-13-2010 |
20100135854 | BIOSENSOR HAVING TRANSISTOR STRUCTURE AND METHOD OF FABRICATING THE SAME - Provided are a biosensor and a method of fabricating the same. The biosensor has a transistor structure including a gate electrode formed on a substrate, a gate insulating layer formed on the gate electrode, source and drain electrodes formed on the gate insulating layer, and a channel region formed between the source and drain electrodes. Here, the channel region includes an active layer formed of an active polymer sensing an antigen-antibody reaction and a hydrophilic nano particle. The active layer is formed through direct printing, for example, inkjet printing. The biosensor having such a structure can be increased in reactivity between an antigen and an antibody and hydrophilicity to improve the sensor's characteristics, fabricated in a large-area process using direct printing, and further facilitates formation of devices on various substrates formed of, for example, plastic. | 06-03-2010 |
20100135855 | METHOD FOR DEPOSITING SUBSTANCES ON A SUPPORT - The present invention relates to a method for depositing a substance on a support, comprising the provision of a substance solution, the provision of a transfer solution capable of activating the support, the deposition of the transfer solution on a predefined position of the support and the deposition of the substance solution on the same predefined position where the transfer solution was placed, whereby an immobilization of the deposited substance at the location of overlap between the deposited transfer solution and the deposited substance solution on said support is achieved. | 06-03-2010 |
20100143193 | Magnetic valves for performing multi-dimensional assays using one microfluidic chip - An apparatus for performing multi-dimensional assays using a microfluidic chip is presented. The apparatus comprises of two crossing series of micro-channels on the microfluidic chip. The apparatus further comprises of a plurality of magnetic valves placed at the crossings and a guiding magnet. When an operator places the guiding magnet in a vicinity of the chip, the guiding magnet produces a proximal magnetic field gradient at a location of each of the plurality of magnetic valves. At the first micro-channel crossing, a magnetic valve controls fluid flow in the first micro-channel, and another magnetic valve controls fluid flow in the second micro-channel at the first micro-channel crossing. Each magnetic valve comprises a magnetic bead and a cavity on the chip next to a corresponding micro-channel section. | 06-10-2010 |
20100143194 | MICROFLUIDIC DEVICE - Provided is a microfluidic device. The microfluidic device includes a sample storage chamber storing sample fluid therein, a detection chamber connected to the sample storage chamber and detecting a specific material of the sample fluid, a cleaning liquid storage chamber connected to the detection chamber and storing cleaning liquid therein, a plurality of fluid passages interconnecting the chambers, and a micropump transferring the cleaning liquid. The microfluidic device precisely inspects a sample fluid although a small amount of the sample fluid flows. | 06-10-2010 |
20100143195 | REACTION WELL FOR AN AUTOMATIC ANALYSIS APPLIANCE - A reaction well, intended for use in an automatic analysis appliance and including an opening at its top end and one or two flaps for partially closing said opening, the flaps being separated by a slot enabling a liquid injection or sampling needle to pass through, and preventing stirrer means contained within the well from escaping. | 06-10-2010 |
20100166607 | Printable hydrogels for biosensors - Methods and apparatus are provided for manufacturing an analyte detecting device. In one embodiment, the method comprises providing a substrate, applying a plurality of layer of materials on said substrate; applying a layer containing at least one mediator; and screen printing a hydrogel on the layer. | 07-01-2010 |
20100166608 | METHOD AND SYSTEM FOR MICROFLUIDIC DEVICE AND IMAGING THEREOF - A biological substrate, e.g., microfluidic chip. The substrate includes a rigid substrate material, which has a surface region capable of acting as a handle substrate. The substrate also has a deformable fluid layer coupled to the surface region. One or more well regions are formed in a first portion of the deformable fluid layer and are capable of holding a fluid therein. The one or more channel regions are formed in a second portion of the deformable fluid layer and are coupled to one or more of the well regions. An active region is formed in the deformable fluid layer. At least three fiducial markings are formed within the non-active region and disposed in a spatial manner associated with at least one of the well regions. A control layer is coupled to the fluid layer. | 07-01-2010 |
20100166609 | MICROCHANNEL CHIP - A micro-channel chip comprising a first substrate and a second substrate bonded together, characterized in that at least one patch of a non-adhesive thin-film layer for generating a micro-channel is formed on the mating surface of at least one of the two substrates, a port that is open to the atmosphere is provided in the first substrate, and at least one end portion of the non-adhesive thin-film layer is communicably connected to the port, further characterized in that an underplate made of a material that is difficult to deform by itself is provided on the underside of the second substrate, the underplate has a recess at the interface with the second substrate that extends from a position that is short of the center of the port toward the non-adhesive thin-film layer, and the width of the recess is greater than that of the non-adhesive thin-film layer. | 07-01-2010 |
20100172798 | METHOD FOR THE PRODUCTION OF AN ANALYTICAL ELEMENT - A method is provided for producing an analytical element comprising at least one test field for analyzing a liquid sample, wherein provision is made for a carrier on which a polymer fabric is arranged. At least one portion of the polymer fabric is irradiated with UV laser light and thereby hydrophobized. | 07-08-2010 |
20100172799 | METHOD FOR THE PRODUCTION OF A MICROFLUIDIC SYSTEM ON A POLYMER SURFACE - A method is provided for producing a microfluidic system on a polymer surface, wherein at least one portion of the polymer surface is irradiated by laser light in a targeted fashion for the spatially-resolved modification of the wettability of the portion of the polymer surface by a liquid sample. | 07-08-2010 |
20100178205 | ANALYZER - An analyzer includes, as a cleaning system, a cleanser tank that contains a cleanser; a cleaning-water tank that contains cleaning water; a connection pipe that connects the cleanser tank with the cleaning-water tank; a pump that is provided to the connection pipe and pumps the cleanser out of the cleanser tank to the cleaning-water tank; a valve that is provided to the connection pipe and adjusts a flow of the cleanser from the cleanser tank into the cleaning-water tank; and a control unit that opens the valve and causes the pump to pump the cleanser out of the cleanser tank to the cleaning-water tank via the connection pipe to clean the inside of the cleaning-water tank and the insides of cleaning-water flow-path constituents that form a flow path through which the cleaning water flows from the cleaning-water tank when the specimen is subjected to an analysis process. | 07-15-2010 |
20100183477 | Methods and apparatus for analyzing an analysis fluid - A meter and test wand system is capable of cooperatively processing an analysis fluid and communicating results to a user. The system includes a meter case including a case front, a case front, a case front, a case bottom, a first case side member, and a second case side member. The first and second case side members connect the case front to case front. The first case side member has a longitudinal dimension between said case front and said case bottom and a latitudinal dimension between said case front and said case front. The first case side member includes a first case ridge; A test wand is capable of receiving an analysis fluid, and includes a cartridge including a cartridge ridge. The cartridge ridge is sized and shaped to matingly engage with said first case ridge to connect said test wand to said meter case. | 07-22-2010 |
20100183478 | HEAT-REDUCTION METHODS AND SYSTEMS RELATED TO MICROFLUIDIC DEVICES - A system and method for preventing or reducing unwanted heat in a microfluidic of the device while generating heat in selected regions of the device. | 07-22-2010 |
20100196203 | Formation of Lipid Bilayers - A method for forming a lipid bilayer across an aperture, comprises: (a) providing a cell having a chamber adjacent to a septum comprising a membrane having an aperture capable of supporting a lipid bilayer; (b) depositing one or more lipids on an internal surface of the chamber; (c) introducing an aqueous solution into the chamber to cover the aperture and the internal surface and to form an interface between the solution and lipids; and (d) moving the interface past the aperture at least once to form a lipid bilayer across the aperture. | 08-05-2010 |
20100196204 | MICROCHIP - A microchip including a separation portion for separating a first component and a second component from a sample containing the first component and the second component, respectively, a first collection portion for collecting the first component, a second collection portion for collecting the second component, a first flow path for guiding the first component from the separation portion to the first collection portion, and a second flow path for guiding the second component from the separation portion to the second collection portion is provided. | 08-05-2010 |
20100215543 | METHODS FOR FABRICATING HIGH ASPECT RATIO PROBES AND DEFORMING HIGH ASPECT RATIO NANOPILLARS AND MICROPILLARS - Methods for fabricating of high aspect ratio probes and deforming micropillars and nanopillars are described. Use of polymers in deforming nanopillars and micropillars is also described. | 08-26-2010 |
20100215544 | HANDHELD MICROCANTILEVER-BASED SENSOR FOR DETECTING TOBACCO-SPECIFIC NITROSAMINES - A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflection indicates a presence of tobacco-specific nitrosamines in the medium. The at least one microcantilever beam can include a silicon base layer and a gold-coated receptor layer with a plurality of thiol molecules having a sulfur head and carboxyl-terminated group. The at least one microcantilever beam can include a silicon base layer and a metal or metal oxide coated receptor layer. Alternatively, the microcantilever beam can be formed by co-absorbing tobacco-specific nitrosamines and silane molecules on a silicon microcantilever surface, wherein the template molecules of tobacco-specific nitrosamines physically co-adsorb between the silane molecules. The template molecules of tobacco-specific nitrosamines are then washed away with a solvent to form a silane monolayer having tobacco-specific nitrosamine cavities. | 08-26-2010 |
20100226822 | Mechanical cartridge with test strip fluid control features for use in a fluid analyte meter - A structure for controlling fluid flow from a sample receiving pad into a lateral flow assay test strip, including: a lateral flow assay test strip; a sample pad abutting the lateral flow assay test strip; a pinch wall positioned to direct fluid flow from the sample pad to the lateral flow assay test strip; a top support structure positioned on top of the test strip; and a bottom support structure positioned underneath the test strip, wherein each of the top and bottom support structures comprise a plurality of separate spaced-apart support ribs positioned along the length of the test strip. | 09-09-2010 |
20100233026 | DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT AND REACTION - The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid. | 09-16-2010 |
20100233027 | CHEMICAL ANALYSIS APPARATUS AND CHEMICAL ANALYSIS METHOD - A chemical analysis apparatus comprising reaction containers containing therein a substance to be analyzed; an agitating mechanism spaced from the substance to be analyzed and agitating said substance to be analyzed with a liquid in said reaction container; and, a measuring portion for measuring physical properties of the substance to be analyzed, said agitating mechanism having a sound supply portion supplying sound waves to the substance to be analyzed, wherein said sound supply portion comprises a mechanism changing, in time, intensity of ultrasonic waves to be irradiated so as to apply pulsation to a swirl flow in the reaction container. | 09-16-2010 |
20100239462 | Assembly of at Least One Microfluidic Device and Mounting Piece - An assembly comprising at least one microfluidic device and a mounting piece, this microfluidic device comprising at least one material layer and at least one first fluidic port, which first fluidic port it situated at least partially in an end surface of the material layer and which mounting piece comprises at least one fluidic component, wherein the mounting piece is coupled to the microfluidic device by means of first coupling means provided for this purpose such that the fluidic component is connected to the first fluidic port. The invention also relates to such a mounting piece. | 09-23-2010 |
20100239463 | LEAD-FREE PIEZOELECTRIC CERAMIC FILMS AND A METHOD FOR MAKING THEREOF - This invention relates to lead-free piezoelectric ceramic films and a method of making thereof. Specifically, the invention is directed to a method for fabricating lead-free piezoelectric free standing films having enhanced piezoelectric properties. The films may be used for a number of applications including incorporation in microelectronic devices such as energy harvesting devices and sensor technologies. | 09-23-2010 |
20100247380 | Module for a Modular Microfluidic System - In order to be able to introduce fluid components extraneous to the system into a modular microfluidic system comprising modules arranged alongside one another which can be connected to one another with fluid connection by connecting parts comprising connecting channels with short connecting paths and good temperature controllability, a module with the following features is provided: the module has a plate-shaped microfluidic part which comprises a fluid channel system and on whose top side, in edge regions to the potentially adjacent modules of the microfluidic system has fluid connections, the fluidic connection to adjacent modules being establishable by means of the connecting parts adjacent in edge regions on the upper side, below the microfluidic part is arranged an insulation vessel which can be filled and flowed through by a temperature control fluid and is concluded at the to by the microfluidic part which serves as a lid. | 09-30-2010 |
20100247381 | PROCESSES AND APPLICATIONS OF CARBON NANOTUBE DISPERSIONS - Disclosed are copolymers of carbon nanotubes, as well as processes and applications of carbon nanotube dispersions. Carbon nanotube emulsions and related technology are also disclosed. The controlled deposition of carbon nanotubes on substrates is also provided. Methods of purifying single-walled carbon nanotubes are also provided. Devices made according to the disclosed methods are further described herein. | 09-30-2010 |
20100254855 | BIOCHIP WITH A THREE DIMENSIONAL MESOPOROUS LAYER AND METHOD FOR FORMING THE SAME - The present invention discloses a biochip comprising a substrate and a three-dimensional mesoporous layer on top of it, wherein the mesoporous layer on top is chemically modified to recognize labeling DNAs, proteins, peptides, saccharides, and cells. In addition, this invention also discloses a method for forming the biochip with a three-dimensional mesoporous layer, including a blending process, a heating process, a coating process, a gelation process, a drying process, and a surface modification process. | 10-07-2010 |
20100266450 | MICROFLUIDIC DEVICE AND METHOD OF MANUFACTURING THE SAME AND SENSOR INCORPORATING THE SAME - The present invention provides a microf luidic device, for instance for molecular sieving or for detecting a target substance in a sample fluid. The device comprises a first substrate ( | 10-21-2010 |
20100278693 | TEST ELEMENT FOR ANALYZING BODY FLUIDS - An analytical test element for determining an analyte in a body fluid comprises a detection area in which the analyte is detected and an application site at which the body fluid can be applied to the test element. The application site is spaced apart from the detection area, wherein at least some of the body fluid applied to the application site moves from the application site to the detection area. The test element also comprises a contamination area which at least partially adjoins the application site, wherein an adhesive substance is applied to at least part of the contamination area of the test element. The adhesive substance adheres to the contamination area of the test element and is able to interact with an excess amount of applied body fluid such that at least some of the body fluid adheres to the test element and thereby an excess amount of body fluid remains in the contamination area. An additional embodiment provides for test elements which, after use, can be stored in a storage container. Another embodiment provides for the production of the test elements. | 11-04-2010 |
20100284858 | PYRROLE END-CAPPED BIPYRIDINE ASSAY POWDER FOR SELECTIVE DETECTION OF ZINC IONS AND A PROCESS FOR THE PREPARATION THEREOF - The present invention provides pyrrole end-capped bipyridine derivative having a general formula (1) useful for the detection of zinc ions in solution. The present invention also provides a process for the preparation of pyrrole end-capped bipyridine derivative having a general formula (1). The present invention further provides a dipstick device by coating the assay powder of formula (1) in alumina over a thermoplastic or a glass solid support. The detection event can be monitored by noting the color change and the intense fluorescence change on the surface of the dipstick. For zinc ions, in addition to the color change an intense fluorescence change from greenish-yellow to red is observed. Detection event by means of fluorescence change is selective for Zn | 11-11-2010 |
20100284859 | Flow Cell Device - A microarray system is disclosed. The microarray system includes a microarray formed on a planar substrate and an incubation chamber formed around the microarray. The incubation chamber has a plurality of interior surfaces including a bottom surface on which the microarray is formed and a top surface that faces the bottom surface and is generally parallel to the bottom surface. At least one of a plurality of interior surfaces is a hydrophilic surface. | 11-11-2010 |
20100284860 | MOLECULES SUITABLE FOR BINDING TO A METAL LAYER FOR COVALENTLY IMMOBILIZING BIOMOLECULES - An article is provided for immobilizing functional organic biomolecules (e.g. proteins, DNA, and the like) through a covalent bond to a thiolate or disulfide monolayer to a metal surface wherein an extra activation step of the surface layer or an activation step of the functional biomolecules or bioreceptors could be avoided. The monolayer can contain, but is not limited to, two moieties. One has a group that resists nonspecific adsorption and another has a group that directly (without activation) reacts with functional groups on the biomolecules. In addition, poly(ethylene oxide) groups are incorporated in the monolayer surfaces to resist the nonspecific adsorption and to enhance the specific affinity interactions. A sensor device including these monolayers is also provided to perform reproducible, sensitive, specific and stable bioanalysis. | 11-11-2010 |
20100290951 | SURFACE-BASED AMMONIUM ION SENSOR: AN ELECTRODE DERIVATIZED WITH A SELF-ASSEMBLED MONOLAYER - A compound sensitive to and selective for ammonium ions over other ions. A sensor fabricated from a self assembled monolayer of said compound on gold, exhibiting sensitivity and selectivity for ammonium ions over other ions in aqueous solutions, including blood. A method of preparation of said compound and said sensor. | 11-18-2010 |
20100329927 | Pipelining Assembly For A Blood Analyzing Instrument - A pipelining assembly for use in a blood analyzing instrument, methods for performing parallel pipelining functions, and methods for processing a plurality of prepared blood samples through a blood analyzing instrument. The pipelining assembly presented generally includes a first sample preparation chamber, a first queuing chamber in fluid communication with the first sample preparation chamber, and a first control valve between the first sample preparation chamber and the first queuing chamber. The pipelining assembly further includes a second sample preparation chamber, a second queuing chamber in fluid communication with the second sample preparation chamber, and a second control valve between the second sample preparation chamber and the second queuing chamber. An analysis chamber is provided to receive first and second prepared blood samples from the in first and second queuing chambers. The presented methods include steps for repeated processing of prepared blood samples through the blood analyzing instrument. | 12-30-2010 |
20100329928 | Sensing device - To provide a sensing device using a piezoelectric sensor having an oscillation area for detection and an oscillation area for reference and capable of achieving a high measurement sensitivity by improving shapes of excitation electrodes. On a quartz-crystal piece | 12-30-2010 |
20110002812 | SAMPLE PACKING DEVICE - Provided is a sample packing device for packing a sample with respect to a microchip for performing reaction of a micro component contained in the sample, the microchip at least including: a sample reservoir; a reaction reservoir; and a channel connected between the sample reservoir and the reaction reservoir, in which a package including a sample chamber packed in advance with the sample is mounted on the microchip so as to pack the sample in the sample chamber into the sample reservoir. | 01-06-2011 |
20110008211 | MICROFLUID CHANNEL, METHOD FOR ITS IMPLEMENTATION, AND MICROFLUIDIC SYSTEM CONTAINING SAID CHANNEL - The invention relates to a microfluidic channel ( | 01-13-2011 |
20110014086 | METHOD OF PRODUCING MICROFLUIDIC DEVICE - There is provided a method of producing a microfluidic device including a substrate having a depressed portion and a cover member, whereby to reduce the dispersion of a geometric individual difference and the possibility that a non-joint area can occur in a joint portion between the substrate and the cover member. At the time of producing the microfluidic device, the depressed portion serving as a channel, a chamber and a reservoir is formed in advance in the substrate and a liquid-state energy ray curable resin is applied to the surface of the substrate in which the depressed portion is formed. The energy ray curable resin is cured by an energy ray irradiation unit and caused to serve as the cover on the depressed portion of the substrate, thereby to form the channel, chamber and reservoir. | 01-20-2011 |
20110020180 | Batch Chemical Analyzer - A batch chemical analyzer is disclosed, the analyzer including a reaction tank ( | 01-27-2011 |
20110020181 | FILTER WITH MEMORY, COMMUNICATION AND CONCENTRATION SENSOR - The present invention describes a system and method for accurately measuring the concentration of a substance within a filter housing. A concentration sensor and a communications device are coupled so as to be able to measure and transmit the concentration of a particular substance within the filter housing while in use. This system can comprise a single component, integrating both the communication device and the concentration sensor. Alternatively, the system can comprise separate sensor and transmitter components, in communication with one another. In yet another embodiment, a storage element can be added to the system, thereby allowing the device to store a set of concentration values. The use of this device is beneficial to many applications. For example, the ability to read concentration values in situ allows integrity tests to be performed without additional equipment. | 01-27-2011 |
20110033338 | MICROFLUIDIC CIRCUIT ELEMENT COMPRISING MICROFLUIDIC CHANNEL WITH NANO INTERSTICES AND FABRICATION METHOD THEREOF - A microfluidic circuit element comprising a microfluidic channel, in which the microfluidic channel has nano interstices formed at both sides thereof and having a height less than that of the center of the channel, gives more driving force of the microfluidic channel and provides stable flow of a fluid. | 02-10-2011 |
20110038757 | IMMUNOASSAY PRODUCT AND PROCESS - The invention is directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips, and other such devices is preferred in doing so. | 02-17-2011 |
20110044855 | SYSTEMS AND METHODS FOR COLLECTION AND ANALYSIS OF ANALYTES - Systems and methods are provided for collecting and analyzing analytes. One embodiment of the invention includes a system for collecting analyte. The system comprises a sampling section disposed on a collection platform and an air source that provides an analyte to be sorbed by the sampling section. The sampling section can be formed of a low pressure drop configuration of sorbent material | 02-24-2011 |
20110052446 | FLOW CELLS AND METHODS OF FILLING AND USING SAME - Various flowcell configurations and systems are provided as are methods of making and using same. The flowcells, systems, and methods of use can be useful in carrying out sequencing reactions and next generation sequencing methods. | 03-03-2011 |
20110076195 | Hydrodynamic Isolation Method and Apparatus - The present invention is a flow cell and method for use in microfluidic analyses that presents highly discrete and small volumes of fluid to isolated locations on a two-dimensional surface contained within an open fluidic chamber defined by the flow cell that has physical dimensions such that laminar style flow occurs for fluids flowing through the chamber. This process of location specific fluid addressing within the flow cell is facilitated by combining components of hydrodynamic focusing with site specific cell evacuation. The process does not require the use of physical barriers within the flow cell or mechanical valves to control the paths of fluid movement. | 03-31-2011 |
20110076196 | PHOTOCHEMICAL REACTOR, LUMINESCENT SCREEN AND PHOTOCHEMICAL PROCESSING SYSTEM - The invention relates to a photochemical reactor ( | 03-31-2011 |
20110081275 | Microfluidic structure - Pressure-operable microfluidic structure for the bubble-free combining of two liquid volumes with a fluid chamber that has a feed opening, as well as an inlet and outlet channel emerging into the fluid chamber, wherein the fluid chamber has a cross section that broadens out relative to the inlet channel in the direction of flow from the inlet to the outlet channel and is designed, thanks to the broadened cross section, to broaden a first liquid volume that is essentially pressure-driven and conducted through the inlet channel and through the fluid chamber to a cross section at least approximately corresponding to the full cross section of the fluid chamber, while the fluid chamber has a holding position and is configured so that a second liquid volume, placed in the fluid chamber through the feed opening, can be held in the region of the holding position and the second liquid volume when the first liquid volume is moved through by pressure can be taken up by the latter and delivered as a combined liquid volume through the fluid chamber and into the outlet channel. | 04-07-2011 |
20110085939 | NODE POLYPEPTIDES FOR NANOSTRUCTURE ASSEMBLY - Engineered proteins are used in the assembly of two-dimensional and three-dimensional nanostructure assemblies, based on systematic design and production of protein node structures that can be interconnected, for example, with streptavidin or streptavidin-incorporating struts to produce structures with defined dimensions and geometry. Nanostructure assemblies having utility as functional devices or as resists for the patterning of substrates have architectures including polygons, polyhedra, two-dimensional lattices, and three-dimensional lattices. | 04-14-2011 |
20110091356 | MICRO-FLUIDIC DEVICE AND SAMPLE TESTING METHOD USING THE SAME - A micro-fluidic device containing an anti-coagulant and a sample testing apparatus equipped with the same are provided. The micro-fluidic device includes a sample chamber which receives a sample, an anti-coagulant chamber which receives an anti-coagulant, a channel which communicably connects the sample chamber to the anti-coagulant chamber, and a valve which opens and closes the channel. | 04-21-2011 |
20110091357 | ANALYTICAL SYSTEMS, DEVICES, AND CARTRIDGES THEREFOR - Described here are systems, devices, cartridges, methods, and kits for detecting or quantifying at least two different analytes using at least two different techniques, in a single sample. The cartridges typically comprise at least two test sites and the location of at least one test site is not dependent on a corresponding measurement device. The systems generally comprise a device, memory, and a processing module. The device comprises a light source, an array detector, and a port configured to accept at least a portion of a cartridge. The processing module is configured to perform an image analysis of the cartridge. The methods comprise the steps of acquiring calibration information, acquiring an image of the cartridge, performing an image analysis, and cycling through specific detection or quantification techniques corresponding to the techniques required by the test sites. Computer readable media are also described. | 04-21-2011 |
20110104009 | CLINICAL EXAMINATION DISK, DISK PACK, AND CLINICAL EXAMINATION DEVICE - A clinical examination disk according to the invention includes a disk body in a disk form, and at least one cell formed in the disk body, wherein the cell comprises a specimen reservoir formed in the disk body and having a specimen injecting port, a reaction tank formed in the disk body so as to position nearer to the outer circumference of the body than a position of the specimen reservoir, and holding a reagent which is reactive with the specimen and is beforehand gelatinized, a first narrow tube formed in the disk body, and communicating to the specimen reservoir and the reaction tank, and a second narrow tube formed in the disk body, and having one end connected to the reaction tank and the other end made open. | 05-05-2011 |
20110116971 | AGITATING DEVICE - An agitating device for agitating a blood sample in a sample container is disclosed. The agitating device includes a base comprising a horizontally-supported shaft, a container holder including a first hand and a second hand, the first hand having a first hole at one end and a first hold portion at other end, the second hand having a second hole at one end and a second hold portion at other end, the first and second holes through which the shaft is inserted, the first and second hands being rotatable relative to the shaft and the first and second hold portions faced each other, and an agitation drive unit including a contact member for contacting the container holder and a drive source for reciprocating the contact member contacting the container holder between a lower position and an upper position. | 05-19-2011 |
20110123398 | THREE-DIMENSIONAL MICROFLUIDIC DEVICES - Three-dimensional microfluidic devices including by a plurality of patterned porous, hydrophilic layers and a fluid-impermeable layer disposed between every two adjacent patterned porous, hydrophilic layers are described. Each patterned porous, hydrophilic layer has a fluid-impermeable barrier which substantially permeates the thickness of the porous, hydrophilic layer and defines boundaries of one or more hydrophilic regions within the patterned porous, hydrophilic layer. The fluid-impermeable layer has openings which are aligned with at least part of the hydrophilic region within at least one adjacent patterned porous, hydrophilic layer. Microfluidic assay device, microfluidic mixer, microfluidic flow control device are also described. | 05-26-2011 |
20110135538 | Microchip - Provided is a microchip having a protrusion to which a device for introducing or discharging a liquid sample, a device for causing the liquid sample to flow, or another device is connected, the protrusion retaining strength. The microchip includes a resin substrate ( | 06-09-2011 |
20110135539 | Microchip and Process for Producing Microchip - A microchip which comprises: a resinous base having a plurality of fine channels formed on one side thereof, one or more cylindrical parts disposed so as to protrude from the other side, and a through-hole which pierces each cylindrical part along the axis thereof and communicates with the fine channel so that the diameter of the inner wall of the through-hole gradually decreases from the tip end of the cylindrical part toward the fine channel at a first inclination angle; and a resinous covering member bonded to that side of the resinous base on which the fine channels have been formed. The microchip has been configured so that a liquid sample can be introduced from the tip end of each cylindrical part through the through-hole. The wall thickness of the cylindrical part on the end side where a liquid sample is to be introduced has been made smaller than the wall thickness thereof on the base side where the cylindrical part has been formed, by forming a step therebetween. | 06-09-2011 |
20110142716 | Microchip and Process for Producing Microchip - A microchip | 06-16-2011 |
20110150702 | MICROFLUIDIC DEVICE AND METHOD OF MANUFACTURING THE SAME - A microfluidic device includes a first substrate including a micro-flow path, and a valve seat protruding into the micro-flow path, a second substrate, coupled to the first substrate, and including a cavity corresponding to the valve seat, a first parylene layer disposed on an inner surface of the first substrate, and a valve gate film provided between the first substrate and the second substrate, such that the valve gate film opens and closes the micro-flow path with air pressure applied between the valve seat and the cavity, the valve gate film having a hydrophilic surface. A portion of the first parylene layer, which is disposed on a lower surface of the valve seat and contacting the valve gate film, has a hydrophobic surface. | 06-23-2011 |
20110150703 | TORTUOUS PATH STATIC MIXERS AND FLUID SYSTEMS INCLUDING THE SAME - Static mixers and fluid systems incorporating one or more of the static mixers. The static mixers may include one or more channels that provide a tortuous path through a body, wherein fluid flowing through each channel defines a downstream direction through the tortuous path created within the channel. The tortuous path of the channel is preferably formed by a set of flow obstacles protruding into the channel and a set of flow restrictions positioned along the channel between the inlet and the outlet. Each flow restriction has a downstream length over which the open cross-sectional area of the channel decreases and then increases when moving in the downstream direction. | 06-23-2011 |
20110165022 | HYDROPHILIC DIAGNOSTIC DEVICES FOR USE IN THE ASSAYING OF BIOLOGICAL FLUIDS - Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary diagnostic devices include lateral flow devices, microfluidic devices and microtiter plates. The devices may also be comprised of low fluorescent material in order to facilitate any diagnostic determination by use of fluorescent emissions. Hydrophilic properties may be imparted to the cover plates or backing strips by physical or chemical treatment thereof. The cover plates or backing strips may exhibit heat sealable or pressure sensitive properties. | 07-07-2011 |
20110165023 | LABORATORY DEVICE UNIT HAVING A LABORATORY DEVICE AND A REMOTE CONTROL - A laboratory device unit ( | 07-07-2011 |
20110171068 | Photostructured Chemical Devices and Methods for Making Same - A photostructurable ceramic is processed using photostructuring process steps for embedding devices within a photostructurable ceramic volume, the devices may include one or more of chemical, mechanical, electronic, electromagnetic, optical, and acoustic devices, all made in part by creating device material within the ceramic or by disposing a device material through surface ports of the ceramic volume, with the devices being interconnected using internal connections and surface interfaces. | 07-14-2011 |
20110171069 | AUTOMATIC ANALYZER - When dispensing from one specimen is repeated, the cleaning liquid adhering to an outer wall of a cleaned dispensing nozzle is likely to be moved into a sample vessel during aspiration of the sample and result in reduced sample concentration or deteriorated analytical accuracy. Thus, the cleaning mechanism has a cleaning range of the dispensing nozzle outer wall which is changed according to a range in which dirt adheres to the nozzle. Additionally, an ejector effect acting between the dispensing nozzle and a cleaning liquid flow prevents a decrease in the concentration of the sample by reducing the amount of cleaning liquid which adheres to the dispensing nozzle outer wall. The cleaning mechanism also uses a liquid level detection function of the dispensing nozzle and a nozzle pipe internal-pressure change detection function to determine a discharge state of the cleaning liquid flow and obtain an appropriate cleaning range. | 07-14-2011 |
20110171070 | SURFACE-MODIFIED SENSOR DEVICE AND METHOD FOR SURFACE-MODIFYING THE SAME - A method for surface-modifying a sensor device is disclosed, which includes the following steps: providing a sensor device, wherein a surface of the sensor device has a metal film; forming a surface-modification layer having a plurality of carboxyl groups on the metal film of the sensor device by isopropyl alcohol plasma; and forming a poly(acrylic acid) layer on the surface-modification layer, wherein the acrylic acid of the poly(acrylic acid) layer is grafted to the carboxyl of the surface-modification layer. A surface-modified sensor device is also disclosed. | 07-14-2011 |
20110176963 | APPARATUS FOR ANALYZING SAMPLE - A apparatus for analyzing sample to prevent a sample from being stuck to a surface of the apparatus for analyzing sample in the course of being injected into the apparatus for analyzing sample. The apparatus for analyzing sample includes a platform having a disk shape. The platform includes chambers and channels, a sample inlet hole which is formed in an outer surface the platform and through which a sample is injected into the platform; an opening which is formed in the outer surface of the platform and through which a residual of the sample, present on the outer surface of the platform around the sample inlet hole, is introduced into a receiving space isolated from the chambers and channels; and a barrier which is formed on the outer surface of the platform around a portion of the opening to prevent the residual of the sample from moving past the opening in a radial outward direction of the platform. | 07-21-2011 |
20110176964 | STIRRING DEVICE AND AN ANALYZING DEVICE - A stirring device and an analyzing device for stirring a liquid retained in a vessel with sound wave. The Stirring device ( | 07-21-2011 |
20110182774 | Plastic Injection-Moulded Part With Embedded Component - A method for producing a plastic injection-moulded part having an insert made of a material different from the plastic material is provided, the method comprising the steps of: (a) introducing and positioning the insert in a cavity of an injection mould; (b) setting the clamping force of the injection mould on a clamping mechanism to a maximum force predetermined by the material of the insert; and (c) seamlessly encapsulating the insert with the plastic material of the plastic injection-moulded part inside the injection mould, wherein the encapsulating is seamless or complete. | 07-28-2011 |
20110182775 | ANALYTICAL INSTRUMENT AND METHOD FOR MANUFACTURING SAME - An analytic instrument ( | 07-28-2011 |
20110189052 | System For The Analysis Of Liquid Samples - A system for the automated analysis of liquid samples having one or more processing units for reaction between the samples and one or more reagents to thereby obtain reaction products is disclosed. Disclosed also are a sample unit for supplying the samples to the one or more processing units; a reagent unit equipped with plural reagent vessels containing one or more reagents for mixing with the samples; a distribution unit for distributing fluids including the one or more reagents provided with plural distribution lines, at least some of which are connected to the reagent vessels and the one or more processing units; and at least one analytical unit for analyzing the samples based on the reaction products, in which the analytical unit may include at least one detector for detecting the reaction products. | 08-04-2011 |
20110189053 | SAMPLE PROCESSING SYSTEM - A sample processing system comprising: a plurality of sample processing units; and a transport apparatus for transporting a sample to any of the plurality of sample processing units, wherein the transport apparatus comprises a communication section for communicating with an apparatus external to the transport apparatus and a controlling section for setting the transport apparatus in a start-up state when the communication section have received a start-up command signal from the external apparatus. | 08-04-2011 |
20110194976 | DETECTION DEVICE AND SYSTEM - A detection device and system are provided. The detection device includes a detection capacitor and a Field Effect Transistor (FET). The detection capacitor has a reactive material layer reacting to a specific functional group in a fluid, and first and second electrodes disposed on the both surfaces of an insulating layer, and the FET has a source electrode connected with the second electrode, a gate electrode connected with the first electrode, and a drain electrode. Here, the insulating layer of the detection capacitor is thicker than a gate insulating layer of the FET. | 08-11-2011 |
20110194977 | LIQUID CONTAINER FOR ANALYSIS - A liquid container for analysis is provided to prevent outside liquid leakage from occurring when a needle is inserted into a seal part of a liquid container for analysis. The liquid container for analysis may contain a liquid for analysis and may include: a container main body formed having an opening part that enables the liquid for analysis to be led out; a seal part that seals the opening part; and a guide part that is provided outside the seal part, serving as a guide for inserting a liquid lead-out needle into the seal part, and upon insertion of the liquid lead-out needle into the seal part, coming into substantially liquid-tight contact with an outer circumferential surface of the liquid lead-out needle. | 08-11-2011 |
20110200486 | DEVICE FOR PREPARING AND/OR TREATING A BIOLOGICAL SAMPLE - A device for preparing and/or treating a biological sample including an assembly of storage chambers and/or reaction chambers intended for receiving a fluid, the chambers being separated by walls so as to form an assembly of adjacent chambers. The device includes a base and a drawer including the assembly of adjacent chambers, the drawer being movable in relation to the base, the drawer including a contact surface connected to first means for establishing fluid communication connected to the inside of at least one chamber, the contact surface of the drawer being intended to be positioned facing a contact surface of the base including at least one position at which second means for fluid communication connected to detection means are placed. | 08-18-2011 |
20110206557 | BIOLOGIC FLUID ANALYSIS CARTRIDGE - A biological fluid sample analysis cartridge is provided. The cartridge includes a housing, a fluid module, and an analysis chamber. The fluid module includes a sample acquisition port and an initial channel, and is connected to the housing. The initial channel is sized to draw fluid sample by capillary force, and is in fluid communication with the acquisition port. The initial channel is fixedly positioned relative to the acquisition port such that at least a portion of a fluid sample disposed within the acquisition port will draw into the initial channel. The analysis chamber is connected to the housing, and is in fluid communication with the initial channel. | 08-25-2011 |
20110206558 | ANALYTICAL PRETREATMENT DEVICE - The present invention relates to an analytical pretreatment device, comprising a supporting material | 08-25-2011 |
20110206559 | Decontamination Method And System Implementing It - The method of microbiological decontamination of a machine comprising an enclosure ( | 08-25-2011 |
20110223063 | SAMPLE ANALYZER AND NON-TRANSITORY STORAGE MEDIUM - The present invention is a sample analyzer comprising: a reagent storage configured to store a reagent container containing a reagent used for analyzing a sample, wherein the reagent storage comprises a liquid storing section which stores a liquid such that a surface of the liquid contacts an air within the reagent storage; and a liquid supply unit configured to supply the liquid into the liquid storing section. | 09-15-2011 |
20110229375 | Microfluidic System for Purposes of Analysis and Diagnosis and Corresponding Method for Producing a Microfluidic System - A microfluidic system for purposes of analysis and diagnosis is made up of layers arranged substantially one above the other. The microfluidic system includes at least a first and a second conducting-through layer, which respectively comprise at least one channel for a fluid to be conducted through in the respective conducting-through layer. The microfluidic system further includes at least one chip layer, which comprises at least one active, micromechanical element, the active, micromechanical element being in operative connection with at least one of the channels, and the chip layer being arranged between the first and the second conducting-through layer, and the channels being fluidically connected to one another. A corresponding production method is disclosed in addition to the microfluid system. | 09-22-2011 |
20110236260 | Digital Barcode Nano-Wire and System for Bio-Sensing Using the Same - Provided are a barcode nano-wire for decoding a hard magnetic segment by using highly sensitive magnetic sensors and a bio-sensing system using the barcode nano-wire. Integration of hard magnetic and non-magnetic segments produces the barcode nanowire and magnetic segments are detected using highly sensitive magnetoresistance sensors. The non-magnetic segment uses a non-magnetic material and a specific biomolecule for bioanalysis is immobilized at a specific portion of the barcode nano-wire. The hard magnetic material has an advantage of higher coercivity and high remanence magnetization, which is considered as an important parameter in selecting the material. The hard magnetic segments produce distinguishable strong stray fields for individually detecting segments using conventional magnetic sensors for multiplexed bioanalysis. | 09-29-2011 |
20110236261 | SENSING DEVICE FOR DETECTING TARGET ELEMENTS IN A FLUID - The invention relates to a sensing device for sensing target elements in a fluid. The sensing device comprises a substrate ( | 09-29-2011 |
20110243794 | BIOLOGIC FLUID ANALYSIS CARTRIDGE WITH DEFLECTING TOP PANEL - A cartridge for analyzing a biologic fluid sample is provided that includes a base plate, a sample inlet port, a first chamber wall, a second chamber wall, and an optically transparent cover panel disposed in contact with the first and second chamber walls. The base plate has a body with a chamber surface, a body passage, and a chamber entry passage. The body passage is in fluid communication with the chamber entry passage, and the chamber entry passage extends through to the chamber surface. The sample inlet port has an inlet passage in fluid communication with the body passage. The first and second chamber walls each have a height extending outwardly from the chamber surface, and the two walls are spaced apart from one another. The cover panel is sufficiently flexible to deflect and contact a central region of the chamber surface. | 10-06-2011 |
20110243795 | CHIP FOR ANALYZING FLUIDS BEING MOVED WITHOUT AN OUTSIDE POWER SOURCE - A chip for analyzing fluid being moved without an outside power source is disclosed. A chip for analyzing fluid being moved without an outside power source according to the present invention comprises: a pre-treatment portion into which a target-being analyzed substance is injected and received; a channel portion through which the fluid received in the pre-treatment portion is moved and in which specific reaction of the fluid such as an antigen-antibody reaction is conducted; and a washing portion into which the fluid passing through the channel portion is received wherein the pre-treatment portion includes: a specimen injection portion into which the fluid is injected; a first buffer portion having a step difference with respect to the specimen injection portion for the fluid to be firstly received; and at least one specimen leading guide which is provided between the specimen injection portion and the first buffer portion and destroys surface tension of the fluid flow moving from the specimen injection portion to the first buffer portion side and thus stabilizes flow surface of the fluid. According to the present invention, a moving pattern of the fluid passing through a channel portion is formed evenly and thus bubble creation is decreased and reproducibility thereof is ensured and further a signal detection from a target-being analyzed substance is performed easily. | 10-06-2011 |
20110256023 | SAMPLE PLATE FOR A BIOCHEMICAL ANALYZER - A sample plate for a biochemical analyzer is provided, which includes a main shaft, an inner plate, an outer plate, a refrigeration bin, a tubing portion, a cooling fluid inlet and a cooling fluid outlet. | 10-20-2011 |
20110256024 | Modular Analyte Monitoring Device - A modular analyte monitoring device comprising a base module and an attachment module is disclosed. The attachment module is removably coupled to the base module and includes a program storing component having a program update stored therein to be transmitted to the base module when coupled. The base module may thereafter operate using the program update. | 10-20-2011 |
20110262304 | METHOD OF FLUID CONTROL IN MEDICAL DIAGNOSTIC MEDIA - Migration of liquid samples on diagnostic test strips is prevented by dividing the test strips into reagent-containing pads spaced about 0.3 to 3 mm apart with a laser. | 10-27-2011 |
20110262305 | Vessel with RFID Tag - The present invention relates to a vessel ( | 10-27-2011 |
20110268611 | LIQUID-MIXING APPARATUS, CHEMICAL TESTING APPARATUS, AND ENDOSCOPE PROCESSING APPARATUS - A liquid mixing apparatus of the present invention includes: a first tank; a first introduction section that introduces a first liquid into the first tank; a second introduction section that introduces a second liquid into the first tank; a first opening portion provided above a highest liquid level of the first tank; a second tank; a third introduction section that introduces a third liquid into the second tank; a second opening portion provided above a highest liquid level of the second tank; a liquid transfer conduit that connects a bottom surface portion of the first tank and a bottom surface portion of the second tank; an opening/closing valve provided in the liquid transfer conduit; a gas transfer conduit having one end arranged above the highest liquid level in the first tank and another end arranged above the highest liquid level in the second tank; a pump capable of forward/reverse operation that can transfer a gas in two directions inside the gas transfer conduit; and an atmospheric release control section that controls opening and closing of the first opening portion and the second opening portion. | 11-03-2011 |
20110268612 | MICROCHANNEL INTO WHICH A POROUS POLYMER IS INSERTED - A microchannel is disclosed. The present invention relates to a microchannel having a porous polymer inserted therein, more particularly, to a microchannel including a channel body and a porous polymer inserted in a surface of the channel body to be employed as a valve which can locally maximize a surface area of reaction between samples and reagents and which can control flow of a fluid in the microchannel. | 11-03-2011 |
20110286885 | MICROFLUIDIC DEVICE HAVING NORMALLY OPEN TYPE MICROVALVE AND METHOD OF MANUFACTURING THE MICROFLUIDIC DEVICE - A microfluidic device includes a microvalve formed by disposing a thin elastic film and a valve seat in a microfluidic channel of the microfluidic device. The microvalve is a normally open type valve in which the elastic film does not contact the valve seat. According to the microvalve of the microfluidic device, an additional process for separating the elastic film from the valve seat is not required. Accordingly, the microfluidic device may have a relatively simple manufacturing process. Also, since an initialization operation to use the microfluidic device is not required, the flow of a fluid in the microfluidic device may be efficiently controlled without additional processing steps. | 11-24-2011 |
20110286886 | LABORATORY INSTRUMENT FOR THE PREPARATION OF SAMPLES - A laboratory instrument for the preparation of samples includes a base housing with a work compartment enclosed by protective walls, at least one multifunctional work head having the ability to turn about a rotary axis pivotally supported on the base housing. At least two defined functional positions that can be aligned with at least one container platform which is arranged in the work compartment. The first functional position contains a receiving device which serves to hold a dosage-dispensing device with free-flowing dosage material, and each of the other functional positions contains an additional device. At least one of the protective walls has a cutout opening, and the at least one multifunctional work head is arranged partially in the cutout, so that portions of the at least one multifunctional work head lies both inside and outside of the work compartment. | 11-24-2011 |
20110293478 | DEVICE FOR REDUCING EVAPORATION IN A REAGENT BOTTLE - A device reducing evaporation in a reagent bottle, in particular in an automatic appliance for analyzing samples, the device being in the form of a tube inserted into the bottle and including, in its top portion, an annular rim for bearing on the top end of the neck of the bottle, and means for centering in the neck of the bottle. | 12-01-2011 |
20110300022 | TEMPERATURE-ADJUSTABLE BIOCHIP ASSEMBLY - A temperature-adjustable biochip assembly has a biochip with a microfluidic channel embedded inside and a temperature-controlling unit including a substance sited at a surface of the biochip, a cyclic guiding module passing through the substance, and a fluid flowed inside the cyclic guiding module, with the cyclic guiding module having a fluidic installed in the substance for guiding the fluid and a temperature-controlling component for modulating the temperature of fluid. | 12-08-2011 |
20110311396 | REAGENT PREPARATION APPARATUS AND SPECIMEN PROCESSING SYSTEM - This reagent preparation apparatus prepares a reagent supplied to a measurement portion measuring a specimen with the reagent. The reagent is prepared from a first liquid and a second liquid different from the first liquid. The reagent preparation apparatus comprises a reagent preparation portion preparing the reagent and a control portion acquiring reagent information related to the reagent prepared by the reagent preparation portion, acquiring supply time information related to a time when the reagent prepared by the reagent preparation portion was supplied to the measurement portion and outputting the reagent information and the supply time information. | 12-22-2011 |
20110318227 | SWITCHES FOR MICROFLUIDIC SYSTEMS - A microfluidic system including a substrate in sheet form, at least one hydrophilic microfluidic channel supported on a surface of the substrate, and at least one function component formed as part of the substrate for providing a functional component for the microfluidic channel wherein the functional component comprises at least one cut within the substrate for providing a switch or filter component for the microfluidic channel. | 12-29-2011 |
20120003123 | FECAL SAMPLING DEVICE AND METHOD - A device for testing a specimen comprising a first panel, a metering aperture structure having a plurality of metering apertures formed therein for receiving the specimen therethrough, a second panel opposite the first panel, a sheet disposed between the first and second panels, the sheet including a test area aligned with the plurality of metering apertures, a spacer element disposed between the first panel and the sheet, wherein the metering aperture structure is spaced away from the test area thereby improving readability of the testing. A method of manufacturing a specimen testing device is also disclosed. | 01-05-2012 |
20120003124 | CHEMICAL ANALYSER - A chemical analyser analyses a sample for a target chemical. The sample and reagent are added to a measurement cell until a detectable change is observed. A reference compound, which does not take part in the reaction between the target chemical and reagent, is added to the reagent. By measuring the concentration of the reference compound, the amount of reagent used may be determined. In one embodiment, a mechanism introduces the sample, adds reagent, mixes, cleans, and flushes the measurement cell, which incorporates a longitudinal chamber having inlets for the sample and reagent and an outlet for measured sample/reagent mixtures. A detector located in or adjacent to the chamber between the inlets and outlet and a piston movable in the chamber carries seals such that movement of a piston sequentially opens the inlets and expels the fluid. The analyzer also includes a device that delivers reagent to a measurement cell. | 01-05-2012 |
20120020835 | Microchip - A microchip having a substrate, a cover member joined to one surface of the substrate, and a flow path formed on at least one of joined surfaces of the substrate and the cover member, wherein the microchip includes: a well which is an first opening for communicating into the flow path with a surface opposite to the joined surface of the substrate and is arranged on the substrate; and a chimney which is a member arranged so as to project from the surface opposite to the joined surface of the substrate and has an second opening which communicating into the well, wherein a liquid rise prevention section is formed in the chimney to prevent the liquid from rising to a top portion of the chimney. | 01-26-2012 |
20120076693 | CAPILLARY FLOW TEST ASSEMBLY - A capillary flow test assembly, including: a receptacle having an opening to receive a sample collection device including a sample to be tested using a capillary flow test, the receptacle containing: (i) one or more chemical entities to interact with the sample prior to performing the test, including one or more liquids contained in one or more packages; (ii) a release component configured to release the one or more liquids from the one or more packages to allow the one or more chemical entities to interact with the sample and thereby provide at least one interaction product for the test; (iii) a capillary flow test pad assembly configured to receive the at least one interaction product and to perform the capillary flow test thereon; and (iv) a delay component configured to delay or prevent transport of the one or more chemical entities and the sample to the capillary flow test pad assembly to allow time for the interaction to occur. | 03-29-2012 |
20120100041 | MICROFLUIDIC DEVICE HAVING A FLOW CHANNEL - A microfluidic device having a flow channel comprising a hydrophobic membrane to improve control of flow and control of processing conditions in the flow channel, and to improve the removal of gas bubbles from the flow channel of the microfluidic device. In addition, the invention enables the process controls of the microfluidic device to know when gas bubbles have been removed, so that the next step in the process can be carried out. | 04-26-2012 |
20120107175 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM - A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module. | 05-03-2012 |
20120121464 | APPARATUS FOR PRETREATING BIOLOGICAL SAMPLES, AND MASS SPECTROMETER EQUIPPED WITH SAME - A clinical laboratory apparatus includes a pretreating apparatus having a high separation capability and providing high data reproducibility and reliability and a mass spectrometer is provided which executes fully automatic processing from pretreatment to detection. The pretreating apparatus that includes a cartridge for holding an extraction agent for solid-phase extraction, a pressure-loading unit for applying a pressure load to any cartridge mounted on the solid-phase extraction cartridge-retaining unit, a receiving tray mechanism for receiving a sample extracted from the cartridge, and a liquid-level sensor for detecting liquid levels in the receiving tray as well as in the cartridge, conducts feedback control for the pressure-loading unit to open its pressure release valve upon the liquid-level sensor detecting that the liquid level in the receiving tray mechanism has reached a preset liquid-level position. | 05-17-2012 |
20120156098 | DISPENSING DEVICE AND ANALYZER - Provided are a dispensing device and an analyzer capable of improving dispensing accuracy as well as improving jamming detection accuracy by realizing a short distance between a syringe and a suction tip. The dispensing device | 06-21-2012 |
20120164026 | CERAMIC INJECTION NEEDLE | 06-28-2012 |
20120189496 | SPREADING LAYER AND METHOD FOR PRODUCING AN ANALYSIS ELEMENT SPREADING LAYER - Methods of producing an analysis spreading layer for absorbing a liquid to be analyzed, by: supplying a porous membrane having a bottom, a top and a thickness D, the size of the pores of the membrane increasing over its thickness D; cutting the membrane at a predefined distance, the spreading layer being a sublayer with a thickness d less than the starting thickness D, the pores of the spreading layer having a fluid connection to one another in such a manner that it is permeable to a liquid. The membrane surface is formed by removing a sublayer of the membrane being the liquid outlet side of the spreading layer. The mean size of the pores on the liquid outlet side is at least 1 μm. | 07-26-2012 |
20120195796 | SAMPLE LIQUID SUPPLY DEVICE, SAMPLE LIQUID SUPPLY DEVICE SET, AND MICROCHIP SET - A sample liquid supply device includes a container tip into which the sample liquid is introduced, a hollow needle provided at one end of the container tip such that a hollow part thereof communicates with inside of the container tip, and a sealing member that covers an opening from which the sample liquid is introduced, wherein the sealing member has a puncture-sealing property achieved by elastic deformation. | 08-02-2012 |
20120207646 | HEAT INSULATOR - The present invention provides a heat retaining device for solving problematic adhesion of a container to the heat retaining device. The heat retaining device includes a supporting rod, a top plate, a bottom plate, a heat retaining body, and a supporting spring. A pressing force applied to the container contained in the hole of the heat retaining body compresses the supporting spring to move the heat retaining body downward along the supporting rod. Release of the pressing force moves the heat retaining body upward by an elastic force of the supporting spring until the heat retaining body comes into contact with the top plate. | 08-16-2012 |
20120213668 | COVER OPENER AND AUTOMATIC ANALYZING DEVICE USING SAME - A cover opener for opening a cover | 08-23-2012 |
20120219457 | BIOLOGIC FLUID ANALYSIS CARTRIDGE WITH SAMPLE HANDLING PORTION AND ANALYSIS CHAMBER PORTION - A biological fluid analysis cartridge is provided. In certain embodiments, the cartridge includes a base plate extending between a sample handling portion and an analysis chamber portion. A handling upper panel is attached to the base plate within the sample handling portion. A collection port is at least partially formed with the handling upper panel. An initial channel and a secondary channel are formed between the handling upper panel and the base plate. The collection port and initial and secondary channels are in fluid communication with one another. A chamber upper panel is attached to the base plate within the analysis chamber portion. At least one analysis chamber is formed between the chamber upper panel and the base plate. The secondary channel and the analysis chamber are in fluid communication with one another. | 08-30-2012 |
20120224996 | STACK OF TEST STRIPS AND METHOD FOR THE PRODUCTION THEREOF - A stack of test strips comprises individual test strips which are stacked over each other and carry a test field for examining a bodily fluid sample. Test strips lying one on top of the other are detachably adhesively bonded to each other so that the test strips can be individually removed from the stack, wherein the test fields are packed in chambers and adjacent test strips form the bottom and the lid of such a chamber. A method for producing such a stack of test strips is also disclosed. | 09-06-2012 |
20120237398 | SPECIMEN ANALYZER - A specimen analyzer comprising: a reagent refrigerator configured to store and cool a reagent container; a measurement unit configured to measure a specimen by using a reagent in the reagent container cooled by the reagent refrigerator; wherein the reagent refrigerator comprises: a housing configured so that an upper portion of the housing is openable and closable; a reagent container table configured so that the reagent container is set thereon, wherein the reagent container table is arranged within the housing so as to space away from a bottom of the housing; a first member arranged so as to face a side surface of the reagent container set on the reagent container table; and a second member arranged lower than the reagent container table, wherein the second member has a higher thermal conductivity than that of the first member. | 09-20-2012 |
20120237399 | MODIFICATION OF SURFACES TO INCREASE THE SURFACE TENSION - The invention concerns an analytical test element in which the sample liquid is transported from a sample application site to a determination site, where a detection site lies upstream of the sample application site in the transport direction. The analytical test element has at least one surface which is composed of at least one element that can be oxidized with water or an alloy that can be oxidized with water which has been treated by the action of boiling water or water vapour. | 09-20-2012 |
20120251390 | Method for Recovering Metal and Kit for Recovery of Metal for Use in the Same - A method for recovering a metal, capable of recovering a metal easily without requiring the use of an organic medium, is provided. A first complex between a first chelating agent and a metal present in a sample is formed in a first mixture prepared by mixing the first chelating agent and the sample. Then, the first complex is recovered from the first mixture, and a second complex between the metal derived from the first complex and a second chelating agent is formed in a second mixture prepared by mixing the first complex and an aqueous solution of the second chelating agent. The aqueous solution is under the pH conditions where the first chelating agent can be insoluble in the aqueous solution. Then, a liquid fraction containing the second complex is recovered from the second mixture. Thus, the metal can be recovered. | 10-04-2012 |
20120251391 | AUTOMATIC ANALYZER - An automatic analyzer comprises selection means for selecting whether a preparatory operation, specified from a plurality of analysis preparation processes of the automatic analyzer, should be executed in an initial process at the powering on of the analyzer or after the start of the actual analysis (i.e., in parallel with the sample analysis operation). For example, the automatic analyzer is equipped with means which allows the analyzer to execute a “system liquid replacement operation”, a “sample nozzle pressure sensor checking operation”, a “reaction vessel discarding operation” and a “pre-cleaning liquid replacement operation” which among various operations that are executed in the preparation process in conventional immunological analyzing apparatus in processes other than the preparation process. | 10-04-2012 |
20120269682 | AUTOMATIC ANALYZER - The present invention provides an automatic analyzer including: an analyzing unit that includes an analyzing mechanism and a dispensing reagent cassette storage for storing a reagent cassette for dispensing; a reagent replenishing unit including a replenishing reagent cassette storage for storing in advance a reagent cassette for replenishing to be supplied as the reagent cassette for dispensing; and means for ejecting from the replenishing reagent cassette storage the reagent cassette for replenishing that cannot be supplied as the reagent cassette for dispensing. | 10-25-2012 |
20120275956 | SAMPLE ANALYZER AND STORAGE MEDIUM - A sample analyzer comprising: a measurement unit holds a reagent to be used in a sample measurement and measures a sample by using the reagent; a memory storing a usage amount of the reagent used by the measurement unit; a controller calculates an estimated usage amount of the reagent for a specific day, based on the usage amount of the reagent stored in the memory; and a display, wherein the controller controls the display to show a screen including graphic information illustrating a remaining amount of the reagent held by the measurement unit and the estimated usage amount of the reagent for the specific day, first numerical information indicating, by means of a numerical value, the remaining amount of the reagent, and second numerical information indicating an excess or shortage amount of the remaining amount of the reagent relative to the estimated usage amount of the reagent. | 11-01-2012 |
20120275957 | TEST-SENSOR CARTRIDGE - A test-sensor cartridge comprising a plurality of test sensors adapted to assist in determining an analyte concentration of a fluid sample. The cartridge further comprises a plurality of walls forming a cavity therein. The cavity is adapted to include the plurality of test sensors. At least one of the plurality of walls forms at least one aperture. The cartridge further comprises a lid adapted to enclose the cavity. The cartridge further comprises a locking feature adapted to lock the lid to one or more of the walls. The locking feature is adapted to be disengaged by the at least one aperture receiving a projection of an analyte-testing instrument. | 11-01-2012 |
20120282138 | INTEGRATED FLUID ANALYTE METER SYSTEM - An integrated meter system for determining information related to an analyte of a fluid sample includes a meter including a housing and a plurality of test sensors. Each of the plurality of test sensors includes a penetrating member, a testing portion, and a channel. The channel is adapted to receive the fluid sample. The test sensors are removably located within the housing. At least one of the test sensors is removably connected to an adjacent test sensor. The integrated meter system also includes a test-sensor advancement mechanism that is configured to advance the test sensors. | 11-08-2012 |
20120301360 | NANOSTRUCTURED AEROGEL-THERMOELECTRIC DEVICE, MAKING AND USING THE SAME - Devices used in conjunction with detecting analytes and methods of their manufacture are disclosed. A pre-concentrator device includes a thermoelectric material and an aerogel which includes a nanostructured material disposed on, and in thermal communication with, the thermoelectric material. Such a pre-concentrator is part of a detection system including a sensor. The detection system is used in a method for detecting analytes. | 11-29-2012 |
20120321516 | DEVICE FOR DECAPPING AND RECAPPING SAMPLE TUBES - A decapping/recapping device for removing closures from sample tubes and for reclosing sample tubes with the same closures is presented. The device comprises individual closure holders, each holder comprising a passive closure gripper for holding a closure, at least one actuator for actuating the passive closure gripper when removing a closure from a tube or reclosing a tube with its respective closure and at least one tube gripper cooperating with the at least one actuator for biasing a tube and its closure away from each other when removing the closure and for biasing the tube and its closure towards each other when reclosing the tube. One actuator is coupled to one passive closure gripper of a closure holder when removing a closure from a tube or when reclosing a tube with its respective closure and is decoupled from a passive closure gripper when the closure holder is holding a closure. | 12-20-2012 |
20120328476 | AUTOMATIC ANALYZER - The present invention provides an automatic analyzer for analyzing blood, urine, or other samples in which, for the purpose of reducing the workload of the operator, the process of reagent replacement is automated such that the measurement operation of the analyzer need not be halted during the reagent replacement. A sample rack transfer mechanism and reagent storage/transfer mechanisms are placed on different levels of two-story structure. This configuration allows reagent replacement even when the analyzer is performing an analysis, as well as achieving size reduction of the analyzer. The automation of reagent replacement is achieved by the following: a sensor's detection of the remaining reagent amount in a reagent vessel reaching a particular value; and the analyzer's detection of a measurement request for a sample rack when necessary reagents are not present in any reagent storage mechanism of an analyzer unit. | 12-27-2012 |
20130034467 | METHOD OF MAKING A MICROFLUIDIC DEVICE - A microfabricated device is fabricated by depositing a first metal layer on a substrate to provide a first electrode of an electrostatic actuator, depositing a first structural polymer layer over the first metal layer, depositing a second metal layer over said first structural polymer layer to form a second electrode of the electrostatic actuator, depositing an insulating layer over said first structural polymer layer, planarizing the insulating layer, etching the first structural polymer layer through the insulating layer and the second metal layer to undercut the second metal layer, providing additional pre-formed structural polymer layers, at least one of which has been previously patterned, and finally bonding the additional structural layers in the form of a stack over the planarized second insulating layer to one or more microfluidic channels. The technique can also be used to make cross over channels in devices without electrostatic actuators, in which case the metal layers can be omitted. | 02-07-2013 |
20130121875 | HOLDING DEVICE - A holding device disposed in a bio-detecting instrument for holding a test strip is provided, wherein the holding device comprises a first casing, a second casing, an ejecting member, and an elastic member. The second casing is assembled with the first casing to form an accommodating space, wherein the sensing terminals are extended into the accommodating space. The ejecting member comprises a push rod configured to be reciprocated in the accommodating space. The elastic member is configured to be compressed by driving the ejecting member to an ejecting position, where the push rod enters the accommodating space and is adapted to push the test strip outward without being contact with the sensing terminals, and the elastic member is configured to be released by drawing the push rod back from the accommodating space to an initial position. | 05-16-2013 |
20130121876 | LIQUID ANALYZER DEVICE AND RELATED METHOD - An agitator ( | 05-16-2013 |
20130121877 | MICROCHANNEL CHIP AND MICROANALYSIS SYSTEM - Disclosed is a microchannel chip having an opening on the side of a plate with a lowered production cost. In the microchannel chip, a first plate ( | 05-16-2013 |
20130121878 | REAGENT BOTTLES, VALVES THEREFOR, WASHING MODULES AND METHODS AND APPARATUS FOR DISPENSING REAGENTS - A valve for a reagent bottle is provided, the valve including a resilient membrane configured to extend across an opening in the reagent bottle, the resilient membrane having at least one slit extending therethrough. Also disclosed is a dispensing apparatus for dispensing a reagent from a reagent bottle, the dispensing apparatus comprising: a probe assembly having a probe adapted for insertion into the reagent bottle through the valve and an extraction mechanism for drawing reagent out of the reagent bottle through the probe. A valve opening assembly is provided, which is adapted to open the valve of the reagent bottle such that the probe can pass through the valve without contacting the valve. | 05-16-2013 |
20130136657 | METHOD FOR HYDROPHILIZING SURFACES OF FLUIDIC COMPONENTS AND PARTS CONTAINING SUCH COMPONENTS - A method for at least partially applying a hydrophilic polymer to a measurement channel of a sensor cartridge is provided, which sensor cartridge can be replaceably inserted in an analyzer. The measurement channel comprises at least one sensor element. The method comprises inserting the sensor cartridge into the analyzer, introducing an aqueous solution containing chitosan or a chitosan derivative into the measurement channel of the sensor cartridge, and following a residence time replacing the aqueous chitosan solution with a gaseous or liquid medium, wherein residues of the chitosan or chitosan derivatives remain on the inside surface of the measurement channel and hydrophilize the surface. | 05-30-2013 |
20130183198 | ANALYZER, METHOD FOR DETERMINING A DISPENSED LIQUID AMOUNT, AND NON-TRANSITORY COMPUTER READABLE MEDIUM - An analyzer comprises a dispenser which dispenses a liquid into a container, a detector which comprises a phototransmitter which emits light to the container and a photoreceiver which receives light from the phototransmitter, a moving unit which changes a relative position between the container and the detector, and a controller which determines whether an amount of the liquid in the container is within a predetermined range, based on outputs from the detector at a plurality of the relative positions. | 07-18-2013 |
20130189157 | ROTATING DEVICE AND BLOOD ANALYSIS EQUIPMENT - A rotating device including a main body, a tray, a cover and a motor is provided. The tray is disposed in the main body and is adapted to support an object. The cover is disposed in the main body and is adapted to cover the object. The motor is disposed in the main body and is adapted to drive the object to rotate. When the object rotates to cause a liquid on the object to move away from the object, the cover prevents the liquid from moving to the main body. In addition, a blood analysis equipment is also provided. | 07-25-2013 |
20130195719 | Microchip and Method of Using the Same - A microchip includes fluid circuits therein, formed by uniting together at least a first substrate that is a transparent substrate and a second substrate having grooves provided at the substrate surface and/or through holes penetrating in a thickness direction. The fluid circuits include a liquid reagent receptacle unit to store a liquid reagent, a quantification unit to quantify the liquid reagent or specimen, and an overflow liquid storage unit connected to the quantification unit to store the liquid reagent or specimen overflowing from the quantification unit during quantification. There is also provided a method of using the microchip. | 08-01-2013 |
20130195720 | SAMPLE RACK HANDLING UNIT - A sample rack handling unit comprising an onload section for loading sample racks holding a sample container is presented. The onload section comprises an onload edge and a receiving area with an onload rail longitudinally on the receiving area parallel to the onload edge. The onload rail engages a recess on the rack bottom such that the rack longitudinally slides on the receiving area along the onload rail when the rack is engaged. The onload rail has a base portion and a protrusion extending from the base portion. The protrusion faces the onload edge and the base portion comprises an inclined onload rail side opposite the onload edge such that the recess engages the onload rail when the rack is loaded on the receiving area from the onload edge transversely to the onload rail and the recess disengages the onload rail by sliding the rack towards the onload edge. | 08-01-2013 |
20130202487 | FLUID DELIVERY SYSTEM AND APPARATUS TO PERFORM THE SAME - The present invention is an apparatus and fluid delivery system for automated assays. The apparatus, for example, may be used for immunoassay that uses flow lines for multiple reagents. In one embodiment, the present invention comprises a tray base with one or more fixed or disposable trays for testing samples, multiple flow lines, and multiple valves and the system is used for automatic controlled delivery of different fluids from supply vessels to different trays and discharges them to designated reservoirs or sewage system with minimum of operator actions. The system may include air line to assist supply and discharge the fluids and also coupled with measuring vessels with adjustable volume and valves adapted to interface with a valve operating unit with drive means. The system is controlled by a programmable electronic device that controls the preset values and sequences of valves operation to deliver or discharge the selected fluids in any one or more of plural fluid input ports individually or all together simultaneously, by a set of programmable pinch valves assemblies that pinching or releasing multiple of elastomeric flow conduits, used as a pinch member. The valve operating unit may, in one embodiment, be a single drive unit to control all valve assemblies or, as alternative embodiment, attached to the housing individual mechanism. | 08-08-2013 |
20130216434 | PORTABLE GLUCOSE MONITOR WITH WIRELESS COMMUNICATIONS - A glucose monitor having only a test strip reader and wireless transmission to a remote hand held calculation processor. All glucose data processing occurs in a remote hand held calculator processor with the glucose monitor providing only sensing and wireless transfer of data. In an embodiment, the glucose monitor includes a button for use in wirelessly pairing the monitor to a smart phone for data communication with a non-proprietary communication protocol, and a light source to communicate the progress of the pairing. In a further embodiment, the glucose monitor includes a switch coupled to the strip reader such that power is applied to the monitor when a test strip is inserted and power is removed with the withdrawal of the test strip. In another embodiment, inserting the test strip and activating the switch also places the glucose monitor into the pairing search mode to communication with a host remote processor. | 08-22-2013 |
20130243652 | AUTOMATIC ANALYZER - With an automatic analyzer for analyzing biological samples, it takes a fairly long time from when the power source of the analyzer is turned on until the analyzer reaches a state stable enough to start analyzing. Thus in order to deal with emergency analysis typically at night, the power source needs to be continuously turned on, which incurs power consumption. Accordingly, power switches are provided which, from among the components configuring the automatic analyzer, turn on and off the power source of the component serving as a heat source for raising the temperature inside the analyzer and the power source of the component as a cold source for lowering the temperature inside the analyzer. A startup mode is selectable corresponding to a temperature rise speed inside the analyzer following an analyzer startup and the on/off operations of the power switch coupled to each of the components is controlled accordingly. | 09-19-2013 |
20130243653 | AUTOMATIC ANALYSIS APPARATUS - There is provided a highly reliable automatic analysis apparatus in which a piercing type reagent container is loaded. The apparatus reduces the load on a reagent sampling mechanism, alarms and reagent splashing which are caused by contact between a dispensing nozzle and a piercing cap. In reagent dispensing operation, in specific zones A and B before and after the dispensing nozzle | 09-19-2013 |
20130259746 | SURFACE ACOUSTIC WAVE SENSING DEVICE - A SAW sensor includes a substrate, first and second IDT on the substrate and a detector portion between the first and second IDT. The first IDT generates a surface acoustic wave in response to a high-frequency signal input. The second IDT receives the SAW from the first IDT, and converts the SAW to an electric signal and outputs the electric signal. A one pulse signal, which is input to the first IDT electrode, has an applying time that is at least as long as a delay time of a surface acoustic wave at the detector less an arrival time of a direct wave attributable to electromagnetic coupling between the first IDT and the second IDT electrode, and that is less than an arrival time at the second IDT of a third response wave of the surface acoustic wave from the first IDT. | 10-03-2013 |
20130287630 | HYDROPHILIC COATING FOR NONPOROUS SURFACES AND MICROFLUIDIC DEVICES INCLUDING SAME - A coating formula and method for surface coating non-porous surfaces. Microfluidic devices including said coating achieve desired properties including increased hydrophilicity, improved adhesion, stability and optical clarity. | 10-31-2013 |
20130294971 | SURFACE SAMPLING CONCENTRATION AND REACTION PROBE - A method of analyzing a chemical composition of a specimen is described. The method can include providing a probe comprising an outer capillary tube and an inner capillary tube disposed co-axially within the outer capillary tube, where the inner and outer capillary tubes define a solvent capillary and a sampling capillary in fluid communication with one another at a distal end of the probe; contacting a target site on a surface of a specimen with a solvent in fluid communication with the probe; maintaining a plug volume proximate a solvent-specimen interface, wherein the plug volume is in fluid communication with the probe; draining plug sampling fluid from the plug volume through the sampling capillary; and analyzing a chemical composition of the plug sampling fluid with an analytical instrument. A system for performing the method is also described. | 11-07-2013 |
20130309133 | ANALYSIS CARTRIDGE AND ANALYSIS SYSTEM THEREOF - An analysis cartridge and an analysis system thereof are disclosed. The analysis cartridge comprises a cartridge body, a liquid storage box and a sealing film. The cartridge body has an accommodation portion. The liquid storage box is disposed within the accommodation portion and has a liquid storage tank and a pillar receiving hole. The sealing film covers the pillar receiving hole and seals an opening of the liquid storage tank. | 11-21-2013 |
20130323123 | INTEGRATED TESTING DEVICE - An integrated testing device and method are disclosed. The device includes an integral reservoir for a test fluid, and an actuator, so that the test fluid can be dispensed to facilitate the test. | 12-05-2013 |
20130323124 | BIOLOGICAL SAMPLE MEASUREMENT APPARATUS - A biological sample measurement apparatus includes container ( | 12-05-2013 |
20130336840 | AIR PURIFIER AND TOTAL ORGANIC CARBON MEASURING DEVICE USING THE AIR PURIFIER - An air purifier includes a pump that supplies air to an air purifying unit, a filter arranged at an outlet of the air purifying unit, and pipes and that connect these components. The air purifying unit includes an activated carbon tube constituted by a glass tube filled with granular activated carbon, and a soda lime tube constituted by a glass tube filled with granular soda lime. According to a preferred embodiment, three each of the activated carbon tubes and the soda lime tubes are provided, and the activated carbon tubes and the soda lime tubes are connected alternately in series by tubes so that one activated carbon tube is arranged at a most upstream part and one soda lime tube is arranged at a most downstream part. | 12-19-2013 |
20140003999 | CATALYST DETERIORATION DETERMINATION SYSTEM | 01-02-2014 |
20140017123 | ANALYTICAL AIDS WITH HYDROPHILIC COATING CONTAINING NANOPARTICLES WITH SILICA STRUCTURE AND METHODS OF PRODUCING AND USING THE SAME - Disclosed herein are analytical aids having a surface coated at least partially with a hydrophilic coating, where the hydrophilic coating includes nanoparticles with silica structure and an average particle size in a range from about 1 nm to about 500 nm. Also disclosed are methods of producing the analytical aids, as well as using the analytical aids in, for example, a sampling device containing the at least partially coated analytical aid. | 01-16-2014 |
20140044598 | HIGH-PRESSURE, HIGH-TEMPERATURE MAGIC ANGLE SPINNING NUCLEAR MAGNETIC RESONANCE DEVICES AND PROCESSES FOR MAKING AND USING SAME - Re-usable ceramic magic angle spinning (MAS) NMR rotors constructed of high-mechanic strength ceramics are detailed that include a sample compartment that maintains high pressures up to at least about 200 atmospheres (atm) and high temperatures up to about least about 300° C. during operation. The rotor designs minimize pressure losses stemming from penetration over an extended period of time. The present invention makes possible a variety of in-situ high pressure, high temperature MAS NMR experiments not previously achieved in the prior art. | 02-13-2014 |
20140050620 | METHODS AND SYSTEMS TO COLLECT A BIOLOGICAL SAMPLE - Sample processing methods and systems to collect a biological sample. A device may be configured collect a predetermined volume of a sample in sample chamber, and seal the chamber upon activation. The device may be further configured to mix the mix the sample with a predetermined volume of a reagent and/or mix the sample and the reagent in a pre-determined ration. | 02-20-2014 |
20140086796 | STRIP DISPENSER AND STRIPS FOR USE WITH THE SAME - The present invention relates to product dispensers, and in particular dispensers for products in the form of strips. The product dispenser includes a container having a lid that may be pivotally attached to a base. According to an embodiment, the assembly includes a cartridge housing and a dispensing cartridge. The dispensing cartridge is configured to house a stack of strips. A guide is biased by a spring to push a presser bar against the bottom portion of the stack of the strips toward the dispensing end of the assembly. When a strip is to be dispensed, a slider is moved from a first position to a second position, causing a slider arm to contact and assist in rotating a strip toward a dispensing opening. At least a corner of the rotated strip may protrude through the dispensing opening so that a user may remove the strip from the assembly. | 03-27-2014 |
20140119994 | SAMPLE ANALYZER - Disclosed is a sample analyzer comprising: a measurement section configured to store a reagent or consumable to be used in a measurement of a sample and to measure a sample with the stored reagent or consumable; a display section; and a controller programmed to control the display section to show a changeover support screen configured to help a changeover of an operation of the sample analyzer, the changeover support screen showing a residual amount information related to a residual amount of the reagent or consumable stored in the measurement section. | 05-01-2014 |
20140134048 | ANALYSIS DEVICE - A protective cap | 05-15-2014 |
20140140891 | APPARATUS AND METHOD FOR SEPARATING PLASMA FROM BLOOD AND DELAYED WETTING - Devices and methods are disclosed herein for separating a supernate from a suspension. The apparatus consists of a sample zone, a controllable gate, and an analysis zone. The sample zone holds the suspension. The analysis zone passively transports a supernate formed from the suspension by capillary transport. A controllable gate prevents the suspension in the transport zone from flowing into the analysis zone. The controllable gate can be triggered after the supernate has separated from the suspension to allow the supernate to flow into the analysis zone. | 05-22-2014 |
20140161667 | AUTOMATED ANALYTE SENSOR ORDERING METHODS AND APPARATUS - Methods, systems, and apparatus adapted to automate ordering of test strips for use in an analyte meter device are disclosed. The method, system and apparatus includes inputting information from an indicia on a package of test strips indicative of a quantity of test strips in the package; tracking a number of test strips used in the analyte meter device; and generating an automatic order for additional test strips based on a signal indicating that a reorder threshold has been reached. Numerous additional features and aspects are disclosed. | 06-12-2014 |
20140186214 | MICROCHIP - A microchip including a fluid circuit composed of a space formed inside is provided. The space includes a first space, a second space, and a space connecting portion connecting the first space and the second space, and the space connecting portion has a structure portion restraining liquid moving between the first space and the second space from moving due to wettability with respect to the space connecting portion surface. | 07-03-2014 |
20140271361 | CONTOURED DISPENSER - A blood testing system includes a cartridge loadable into a blood analyzer. One cartridge includes a convex top portion with a blood entry port therein. A dispenser transfers blood in a stoppered test tube to the cartridge. One dispenser includes a contoured, stabilizing base configured to mate with the cartridge convex top portion. The dispenser may further include a hub supported by the base, a cannula extending upward from the hub, and a dispensing tip in fluid communication with the cannula depending downward from the hub and inserted into the blood entry port of the cartridge when the dispenser base is mated with the cartridge convex top portion. | 09-18-2014 |
20140286825 | TEST STRIP FOR MEASURING BIOLOGICAL FLUID - The invention relates to a test strip. The test strip comprises an insulating sheet; a metallic circuit layer disposed on the insulating sheet, the metallic circuit layer including at least an electrode section; a sensing reagent layer provided on the electrode section; an intermediate layer disposed to cover the insulating sheet and the metallic circuit layer, the intermediate layer having an opening to expose the sensing reagent layer and the electrode section; and a cover disposed to cover the intermediate layer and the insulating sheet, and expose part of the metallic circuit layer, the cover having two holes corresponding to the opening. The test strip is provided in a combination of printing manner and chemical plating such as metallic ion replacement or electroless plating to form the metallic circuit layer readily so as to enhance the stability of resistance and the test accuracy. | 09-25-2014 |
20140308164 | Biological Fluid Transfer Device and Biological Fluid Sampling System - A biological fluid sampling transfer device adapted to receive a multi-component blood sample is disclosed. After collecting the blood sample, the biological fluid sampling transfer device is able to separate a plasma portion from a cellular portion. After separation, the biological fluid sampling transfer device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The biological fluid sampling transfer device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The biological fluid sampling transfer device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the biological fluid sampling transfer device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results. | 10-16-2014 |
20140308165 | Biological Fluid Collection Device and Biological Fluid Separation and Testing System - A biological fluid collection device that is adapted to receive a multi-component blood sample having a cellular portion and a plasma portion is disclosed. After collecting the blood sample, the biological fluid collection device is able to separate the plasma portion from the cellular portion. After separation, the biological fluid collection device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The biological fluid collection device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with an anticoagulant. The biological fluid collection device is engageable with a testing device for closed transfer of a portion of the plasma portion from the biological fluid collection device to the testing device. The testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results. | 10-16-2014 |
20140308166 | Blood Sampling Transfer Device and Blood Separation and Testing System - A blood sampling transfer device that is adapted to receive a blood sample having a cellular portion and a plasma portion is disclosed. The blood sampling transfer device is able to separate the plasma portion from the cellular portion. After separation, the blood sampling transfer device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The blood sampling transfer device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The blood sampling transfer device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the blood sampling transfer device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results. | 10-16-2014 |
20140308167 | Biological Fluid Sampling Transfer Device and Biological Fluid Separation and Testing System - A biological fluid sampling transfer device that is adapted to receive and separate a multi-component blood sample is disclosed. After separation, the biological fluid sampling transfer device is able to transfer a plasma portion of the blood sample to a point-of-care testing device. The biological fluid sampling transfer device of the present disclosure also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with an anticoagulant. The biological fluid sampling transfer device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the biological fluid sampling transfer device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results. | 10-16-2014 |
20140334979 | Biosensor and Measurement Apparatus for Same - Provided is a biosensor and a measuring device which may be coupled with each other only when the biosensor and the measuring device mach with each other, thereby obtaining reliable measured results. | 11-13-2014 |
20140356233 | AUTOMATIC ANALYSIS DEVICE AND REAGENT PROCESSING METHOD IN AUTOMATIC ANALYSIS DEVICE - An automatic analyzer is capable of performing a preparation process on a reagent used to measure a highly urgent test item even during analysis operation, and is configured as follows. If there is no parameter for the analysis item regarding a new reagent, the parameters are downloaded. If the priority of reagent preparation is “high,” a sample pipetting scheduling process is temporarily stopped. If the priority of reagent preparation is not “high,” it is determined whether a waiting time limit has been exceeded, and if it has, the sample pipetting scheduling process is stopped temporarily, reagent preparation scheduling is performed, and the sample pipetting scheduling process is resumed. If it is determined that the waiting time limit has not been exceeded, if the priority of reagent preparation is “medium,” and if the reagent preparation mechanism is found available, then reagent preparation scheduling is performed. | 12-04-2014 |
20140377133 | FLUID ANALYSIS CARTRIDGE - Provided is a fluid analysis cartridge that performs a test on a fluid sample. The fluid analysis cartridge includes: a testing part configured to receive a fluid sample and configured to perform a test on the fluid sample; a housing including at least one supply hole configured to supply the fluid sample to the testing part; a filtering part that is disposed between the at least one supply hole and the testing part and is configured to filter a particular material included in the fluid sample; and at least one stepped part provided on a surface of the housing facing the filtering part and that forms a gap between the filtering part and the surface of the housing. | 12-25-2014 |
20150293136 | AUTOMATIC ANALYZER - An automatic analyzer having no limitation on a range of a placeable position on a sample placement disk for patient specimens, emergency specimens, quality control samples, and calibration samples, and being capable of performing analysis while changing the number of simultaneously-measureable samples for each type of each specimen is provided. In the automatic analyzer, either a calibration sample dedicated disk or a patient specimen dedicated disk is placed in an analyzing unit | 10-15-2015 |
20150309000 | ESTIMATING DIFFUSION COEFFICIENT FOR A RESERVOIR STIMULATION FLUID - The subject disclosure relates to matrix acidizing. More specifically, systems and methods are described for estimating a diffusion coefficient for an acid fluid used to stimulate a subterranean reservoir wherein a spent acid is formulated that includes one or more by-products of the reaction between the fluid and rock. A rock sample, such as in the form of a rotating disk is exposed to spent acid under elevated pressure and temperature conditions while the fluid is sampled and analyzed. A diffusion coefficient for the spend acid is estimated. | 10-29-2015 |
20150377895 | Graphical User Interface Pertaining To A Bolus Calculator Residing On A Handheld Diabetes Management Device - A handheld diabetes manager is presented with an improved graphical user interface for a bolus calculator. The bolus calculator is configured to receive blood glucose measurements from a blood glucose measurement module and operates, in response to an input, to compute an insulin recommendation for a patient based in part on the blood glucose measurements. The graphical user interface for the bolus calculator includes a health adjustment screen that enables a user to input a value for health events associated with the insulin recommendation, where the input value represents a cumulative effect of the health events on insulin of the patient and the health adjustment screen presents a different icon for each of the health events associated with the insulin recommendation. | 12-31-2015 |
20160038940 | Microfluidic Products WIth Controlled Fluid Flow - A microfluidic product utilizing gradient surface energy coatings for fluid control comprising a plurality of fluid passages wherein at least one fluid passage comprises a coating configured to control liquid flow wherein the coating configured to control liquid flow comprises a gradient surface energy coating from a proximal location to a distal location on a surface of the fluid passage. The product can include uniform regions and surface gradient regions in the same passage. Coating compositions and product dimensions can be selected to provide control over different flow properties including fluid velocity, reduction and acceleration of fluid flow, and starting and stopping fluid flow. | 02-11-2016 |
20160069859 | MULTISTRIP CARTRIDGE - A test meter for analyzing a body fluid sample applied to a test strip includes an outer housing having an opening, an actuator, and a cartridge positioned adjacent the outer housing. The cartridge further includes a dispensing member connected to the actuator, a plurality of stacked test strips biased toward the dispensing member, and a cartridge outer housing that is adjacent at least a portion of the dispensing member. Each time the actuator is actuated, the dispensing member is rotated to cause movement of one test strip from the plurality of stacked test strips through the opening, and another test strip is biased toward the dispensing member. | 03-10-2016 |