Entries |
Document | Title | Date |
20080213460 | Method of Coating a Polymer Surface with a Polymer Containing Coating and an Item Comprising a Polymer Coated Polymer - A method of coating a surface of a solid polymer substrate, e.g. comprising silicone, thermoplast, thermoset and/or elastomers, with a coating comprising a coat polymer. | 09-04-2008 |
20080233267 | Coated Stent With Evenly Distributed Therapeutic Agent - A stent includes a stent framework and a coating disposed on the stent framework. The coating includes an inner surface and an outer surface. The coating has a circumferential therapeutic concentration zone near the inner surface and a circumferential washed zone near the outer surface. | 09-25-2008 |
20080299288 | Durable, heat-resistant multi-layer coatings and coated articles - A method of providing a durable protective coating structure which comprises at least three layers, and which is stable at temperatures in excess of 400° C., where the method includes vapor depositing a first layer deposited on a substrate, wherein the first layer is a metal oxide adhesion layer selected from the group consisting of an oxide of a Group IIIA metal element, a Group IVB metal element, a Group VB metal element, and combinations thereof; vapor depositing a second layer upon said first layer, wherein said second layer includes a silicon-containing layer selected from the group consisting of silicon oxide, silicon nitride, and silicon oxynitride; and vapor depositing a third layer upon said second layer, wherein said third layer is a functional organic-comprising layer. Numerous articles useful in electronics, MEMS, nanoimprinting lithography, and biotechnology applications can be fabricated using the method. | 12-04-2008 |
20080317939 | Method and System for Irradiation of a Drug Eluting Implantable Medical Device - A method and system for modifying a drug delivery polymeric substrate for an implantable device, such as a stent, is disclosed. | 12-25-2008 |
20090011116 | REDUCING TEMPLATE WITH COATING RECEPTACLE CONTAINING A MEDICAL DEVICE TO BE COATED - An apparatus and a method for applying a coating to a medical device such as a stent, balloon, or catheter, shortly before insertion or implantation are described. The apparatus and method produce uniform consistent coverage of the medical device in a predictable, repeatable and controllable manner and reduce the need for preservative components in the coating or for excessive curing or hardening of the coating. | 01-08-2009 |
20090035446 | Solid Solution Perforator Containing Drug Particle and/or Drug-Adsorbed Particles - A solid drug solution perforator containing drug particles and/or drug-adsorbed or loaded particles with an associated drug reservoir (SSPP system) are provided for delivering therapeutic, prophylactic and/or cosmetic compounds, diagnostics, and for nutrient delivery and drug targeting. For drug delivery, the SSPP system includes an active drug ingredient in particulate form or drug adsorbed on the particle surface in a matrix material that dissolves upon contact with a patient's body. In a preferred method of transdermal drug delivery, an SSPP system containing a drug-adsorbed microparticle penetrates into the epidermis or dermis, and the drug is released from the (dissolving) SSPP system perforator and desorbed from the particles. An additional drug is optionally delivered from a patch reservoir through skin pores created by insertion of the perforator Formulation and fabrication procedures for the SSPP and associated reservoir are also provided. An SSPP system can be fabricated with variety of shapes and dimensions. | 02-05-2009 |
20090074943 | MICRODROP ABLUMENAL COATING SYSTEM AND METHOD - Systems and methods for coating medical devices are provided that allow for relatively precise control over the deposition area and coating uniformity with improved efficiency. A microdrop source is used to provide a flow of coating microdrops. A charging electrode disposed near the outlet of the coating source gives each microdrop an electrostatic charge. As the microdrop travels toward the medical device to be coated, a control electrode alters the trajectory of the microdrop. The invention can include a scanner to scan or image the medical device as the coating is applied and a control system to adjust parameters of the deposition process based on information provided by the scanner. | 03-19-2009 |
20090123639 | RF PLASMA-ENHANCED DEPOSITION OF FLUORINATED FILMS - Low- or atmospheric pressure RF plasma-enhanced thin film deposition methods are provided for the deposition of hydrophobic fluorinated thin films onto various substrates. The methods include at least two steps. In the first step, RF plasma-mediated deposition is used to deposit a fluorinated film onto a substrate surface. In a second step, plasma-generated active sites on the fluorinated film are quenched by reacting them with stable fluorinated gas-phase molecules in situ, in the absence of plasma, to provide a hydrophobic fluorinated thin film having a very low oxygen content. In some instances the hydrophobic fluorinated thin films have an atomic oxygen concentration of no more than about 3%. | 05-14-2009 |
20090148590 | MANDREL COATING ASSEMBLY - Mandrel coating assemblies are provided, as well as methods for coating endoluminal medical devices with a therapeutic agent using the mandrel coating assembly. The endoluminal medical device may be a stent, valve or other medical device, and may include a plurality of interconnected members defining a lumen and plurality of openings positioned along the abluminal surface in communication with the lumen. The mandrel coating assembly may be configured to minimize the coating penetration on the luminal surface of the medical device and/or incidence of webbing or agglomerations of the coating within the openings between the struts. | 06-11-2009 |
20090155449 | MEDICAL DEVICE COATING APPARATUS AND METHODS OF USE - Apparatus and methods are configured to coat a medical device, such as a stent, with a beneficial medicinal agent using one or more liquid feeds and one or more micromist nozzles. In one implementation, an agent coating rig includes a vertical adjustment means, a rotation means, and a traverse adjustment means for moving a medical device along virtually any point on an x or y axis. In additional or alternative implementations, the agent coating rig can further include a secondary horizontal adjustment means that allows adjustment along virtually any point on a z axis. Furthermore, methods and apparatus are provided for distributing the beneficial agent on the medical device, including delivering the beneficial agent efficiently over time. | 06-18-2009 |
20090176004 | Medical Devices and EFAB Methods and Apparatus for Producing Them - Various embodiments of the invention present miniature medical devices that may be formed totally or in part using electrochemical fabrication techniques. Sample medical devices include micro-tweezers or forceps, internally expandable stents, bifurcated or side branch stents, drug eluting stents, micro-valves and pumps, rotary ablation devices, electrical ablation devices (e.g. RF devices), micro-staplers, ultrasound catheters, and fluid filters. In some embodiments devices may be made out of a metal material while in other embodiments they may be made from a material (e.g. a polymer) that is molded from an electrochemically fabricated mold. Structural materials may include gold, platinum, silver, stainless steel, titanium or pyrolytic carbon-coated materials such as nickel, copper, and the like. | 07-09-2009 |
20090176005 | Method And Apparatus For Spray Processing Of Porous Medical Devices - Thermal spray processing and cold spray processing are utilized to manufacture porous starting materials (such as tube stock, wire and substrate sheets) from biocompatible metals, metal alloys, ceramics and polymers that may be further processed into porous medical devices, such as stents. The spray processes are also used to form porous coatings on consolidated biocompatible medical devices. The porous substrates and coatings may be used as a reservoir to hold a drug or therapeutic agent for elution in the body. The spray-formed porous substrates and coatings may be functionally graded to allow direct control of drug elution without an additional polymer topcoat. The spray processes are also used to apply the drug or agent to the porous substrate or coating when drug or agent is robust enough to withstand the temperatures and velocities of the spray process with minimal degradation. | 07-09-2009 |
20090181156 | MARKED PRECOATED MEDICAL DEVICE AND METHOD OF MANUFACTURING SAME - A method of manufacturing a coated medical device, such as a medical guide wire, including at least applying a first colored coating to at least a first portion of an outer surface of a medical guide wire, securing a first end of the medical guide wire, and for each a designated quantity of turns, turn a second end of the medical guide wire upon a longitudinal axis of the medical guide wire. The method of manufacturing also includes securing the second end of the medical guide wire, blocking at least a first portion of the coated surface of the medical guide wire, applying a second contrasting colored coating to at least a second, unblocked portion of the outer surface of the medical guide wire and releasing the first end and the second end of the medical guide wire to display at least one spiral marking formed along a length of the medical guide wire. | 07-16-2009 |
20090208635 | METHOD FOR PRODUCING AN INSULATION TUBE AND METHOD FOR PRODUCING AN ELECTRODE - The present invention relates to a method for producing an insulation tube ( | 08-20-2009 |
20090220675 | Apparatus for producing a biomimetic coating on a medical implant - An apparatus for producing a biomimetic coating on an implantable article is provided. The apparatus includes an outer reactor for containing a biomimetic coating solution and an inner reactor arranged within the outer reactor. The inner reactor is smaller than the outer reactor so as to define a space between the inner and outer reactors. The apparatus also includes a pump system for circulating the biomimetic coating solution. The pump system is arranged to operate in the space between the inner and outer reactors. The inner reactor includes a flow control system that is selectively operable to control the flow of biomimetic coating solution between the outer and inner reactors. | 09-03-2009 |
20090232962 | ANTIMICROBIAL FILTRATION ARTICLE - The present invention relates generally to a filtration article, such as a protective facemask, a method for using a filtration article, and a method for preparing a filtration article. In particular, the invention relates to a protective facemask that cost-effectively offers a broad spectrum of antimicrobial protection through the use of fibers treated with one or more oligodynamic metal and/or salt of an oligodynamic metal. | 09-17-2009 |
20090238948 | Coating process for ophthalmic lenses - The present invention generally relates to a method for coating ophthalmic lenses, preferably contact lenses, more preferably silicone hydrogel contact lenses. In particular, the present invention is directed to a method for forming a coating comprising a polyionic material on a contact lens, preferably a silicone hydrogel contact lens, directly in the primary package and maintaining the coated contact lens within said primary package until insertion of the coated contact lens in the eye of the contact lens user. | 09-24-2009 |
20090311413 | METHOD AND DEVICE FOR RADIOTHERAPY - A radiotherapy method, comprising positioning a predetermined amount of a radionuclide selected from the group consisting of Radium-223, Radium-224, Radon-219 and Radon-220, in proximity to and/or within a tumor of a subject, for a predetermined time period. The predetermined amount and the predetermined time period are selected sufficient for the radionuclide to administering a predetermined therapeutic dose of decay chain nuclei and alpha particles into the tumor. | 12-17-2009 |
20100015321 | SCAFFOLD TREATMENT - DEVICE AND METHOD - An apparatus for treating porous polymeric scaffolds including an enclosure; a support for at least one porous polymeric scaffold, and at least one application outlets within the enclosure for applying a liquid agent onto the top surface of the at least one porous polymeric scaffold; each porous polymeric scaffold being supported on a drained platform above a liquid catchment area within the enclosure and having at least one application outlet directed at its top surface | 01-21-2010 |
20100021619 | LOW FRICTION COATED MARKED WIRE GUIDE FOR OVER THE WIRE INSERTION OF A CATHETER - A wire guide includes a mandrel that has a proximal portion and a distal portion. A coating having a low coefficient of friction is disposed on at least part of the proximal portion and the distal portion of the mandrel, where a part of the proximal portion and distal portion of the mandrel without the coating indicates a marking on the wire guide. This marking on the wire guide allows a user to determine a trimmable length of a catheter, and the low friction coating enables the user to easily advance the catheter over the wire guide. | 01-28-2010 |
20100047434 | FABRICATION OF MONOLITHIC ZONES ON POROUS SCAFFOLD - Processes for preparing medical devices comprising building, by confocally fed, laser-assisted microdeposition, a monolithic biocompatible ceramic coating on a surface of a porous or porogenic, biocompatible substrate; medical devices prepared thereby; and kits comprising them. | 02-25-2010 |
20100075018 | SURFACE MODIFICATION TO IMPROVE LUBRICITY, ABRASION RESISTANCE AND TEMPERATURE RESILIENCE OF LEADS - A medical electrical lead body having an outer surface and including at least one lumen having an inner surface treated with a silane surface modifying agent to form a three-dimensional, densely cross-linked lubricious coating over at least a portion of the inner surface of the lumen. The outer surface of the lead body also may be similarly treated. The lubricious silane coating may reduce the coefficient of friction of the coated surface of the lead body by as much as 80% when compared to an uncoated surface. A reduction in the coefficient of friction may enhance the stringing efficiency of a conductor through the lead body lumen and may enhance its abrasion resistance. | 03-25-2010 |
20100136209 | SYSTEMS AND METHODS FOR APPLYING AN ANTIMICROBIAL COATING TO A MEDICAL DEVICE - Methods for applying an antimicrobial coating to a medical device is disclosed. Generally, the methods comprise providing a medical device, dispensing an antimicrobial coating onto the device, flushing excess coating from the device, and curing the coating onto the device. In one aspect, the coating includes a UV-curable, antimicrobial composition. In this aspect, the medical device can be coated and the coating can be cured with UV light in a manner of seconds. In another aspect, the coating includes an antimicrobial solution that contains an acrylate-type polymer or copolymer. In this aspect, the medical device can be coated and the coating can be heat-cured in a manner of minutes. Both the UV-curable composition and the antimicrobial solution can also include rheological modifiers, as necessary. Additionally, the compositions include one or more antimicrobial agents, which may be selected from a wide array of agents. | 06-03-2010 |
20100143576 | DIRECT APPLICATION OF PRESSURE FOR BONDING POROUS COATINGS TO SUBSTRATE MATERIALS USED IN ORTHOPAEDIC IMPLANTS - A method for constantly controlling a direct application of pressure for bonding porous coatings to substrate materials used in orthopaedic implants. The direct pressure is applied to an interface between the porous coating and the substrate material via a pressure application mechanism unaffected by heat and air pressure conditions of the bonding process. The pressure application mechanism maintains a pressure on the implant which is constantly controlled throughout the bonding process. | 06-10-2010 |
20100159116 | METHOD FOR PRODUCING A MEDICAL DEVICE WITH A CROSS-LINKED HYDROPHILIC COATING - A time and cost effective production method for medical devices with a hydrophilic coating is provided, which ensures adequate adhesion to the substrate, as well as good water retention and low friction properties. Specifically, the method comprises the steps of: providing a substrate; applying, in one or more steps, a coating solution comprising a hydrophilic polymer to a surface of said substrate to form a non-cross-linked hydrophilic coating on said substrate; and irradiating the coated substrate, wherein said irradiation is adapted both to cross-link said hydrophilic coating and to simultaneously sterilize the medical device. | 06-24-2010 |
20100203226 | METHOD FOR FORMING INORGANIC COATINGS - The present invention is directed to a method for forming an inorganic coating on a protein template. The method comprises contacting the template with an anionic polymer interface followed by an inorganic material for a sufficient period of time to allow mineralization of the inorganic material thus forming an inorganic coating on the template. Preferably, the coating is aligned. | 08-12-2010 |
20100247736 | METHOD FOR PRODUCING CALCIUM PHOSPHATE COMPLEX - A method of the present invention for producing a calcium phosphate complex including a substrate and calcium phosphate bonded to a surface of the substrate, the method includes the steps of: (a) treating the surface of the substrate; and (b) bonding the calcium phosphate onto the surface of the substrate after the step (a), the step (a) being the step of placing the surface of the substrate in contact with ozone water. Therefore, the method of the present invention makes it possible to bond calcium phosphate and the substrate at a high bonding strength and at a high coverage. In addition, the method of the present invention provides an easy method for producing a calcium phosphate complex. | 09-30-2010 |
20100255178 | System and Method for Enhancing the Efficacy of Antimicrobial Contact Lenses and Other Surfaces - A system and method of enhancing the antimicrobial and biofilm-resistant efficacy of surfaces that have cationic polyelectrolytes nonleachably bound thereto in order to impart antimicrobial activity to the surface. The system for enhancing antimicrobial efficacy involves brushing, dipping, wiping, spraying, or storing the surface in a solution containing citrate ion. The method involves treatment of the surface with a solution which enhances the antimicrobial and biofilm-resistant efficacy of the surface, and which prevents a loss of the antimicrobial properties of the surface which may occur over time. Preferably, the enhancement agent is citrate ion and the cationic polyelectrolyte is poly(diallyldimethylammonium chloride), also known as poly-DADMAC. The system is particularly beneficial for surfaces of articles such as contact lenses. | 10-07-2010 |
20100260922 | Method for loading nanoporous layers with therapeutic agent - The present invention relates generally to medical devices with therapy eluting components and methods for making same. More specifically, the invention relates to implantable medical devices having at least one porous layer, and methods for making such devices, and loading such devices with therapeutic agents. A mixture or alloy is placed on the surface of a medical device, then one component of the mixture or alloy is generally removed without generally removing the other components of the mixture or alloy. In some embodiments, a porous layer is adapted for bonding non-metallic coating, including drug eluting polymeric coatings. A porous layer may have a random pore structure or an oriented or directional grain porous structure. One embodiment of the invention relates to medical devices, including vascular stents, having at least one porous layer adapted to resist stenosis or cellular proliferation without requiring elution of therapeutic agents. The invention also includes methods, devices, and specifications for loading of drugs and other therapeutic agents into nanoporous coatings. | 10-14-2010 |
20100291286 | LASER-PRODUCED POROUS SURFACE - A method of fabricating a porous or partially porous three-dimensional metal article for use as a tissue ingrowth surface on a prosthesis. The porous article is formed using direct laser remelting in a cross section of a layer of metallic powder on a build platform without fusing thereto. The power, speed, spot size and beam overlap of the scanning laser is coordinated so that a predetermined porosity of the metallic powder can be achieved. Laser factors also vary depending from the thickness of the powder layer, type of metallic powder and size and size distribution of the powder particles. Successive depositing and remelting of individual layers are repeated until the article is fully formed by a layer-by-layer fashion. In an additional embodiment, a first layer of metallic powder may be deposited on a solid base or core and fused thereto. | 11-18-2010 |
20110033608 | PROCESS FOR MAKING COATED, WATER-SWELLABLE HYDROGEL MICROSPHERES - A process for coating water-swellable hydrogel microspheres with various coating materials is described. The coating process described herein is a fluidized bed process, which utilizes inert, cofluidization particles to aid the fluidization of the microspheres. The use of the cofluidization particles increases the efficiency of the coating process and improves the quality of the coating obtained. | 02-10-2011 |
20110039013 | System and Method for Coating a Medical Device - A system and method allows for processing of two groups of medical devices, both groups being alternatingly spray coated within the same enclosure. The two groups repeatedly move back and forth between a spray area and a drying area which is isolated from the spray area. One group moves into the spray area as the other group moves out and into the drying area. Thereafter, the group in the spray area moves out and into the drying area and the other group moves back into the spraying area for a second coating. The alternating process may be repeated any number of times. The spray area may be located inside a sealed spray isolator enclosure and surrounded by gas discharge nozzles. | 02-17-2011 |
20110052787 | SOLVENTLESS METHOD FOR FORMING A COATING ON A MEDICAL ELECTRICAL LEAD BODY - A solventless method for forming a coating on a medical electrical lead is described. The method includes combining particles of a therapeutic agent with a polymeric material in a flowable form in the absence of a solvent to form a uniform suspension. A predetermined amount of the suspension is dispensed onto a portion of the lead and is then cured to form the therapeutic agent eluting layer. Additional layers such as a primer layer, fluoro-opaque layer and/or a topcoat layer can be formed using the solventless method. Employing a solventless method may avoid contraction of the layer being formed due to solvent evaporation during the curing process, and may facilitate greater control over the thickness of the therapeutic agent eluting coating. | 03-03-2011 |
20110052788 | ANTIFOULING HYDROGELS, COATINGS, AND METHODS OF SYNTHESIS AND USE THEREOF - The invention provides an antifouling hydrogel comprising an effective amount of antifouling polymer modified with a compound containing catechol functional groups to yield a modified antifouling polymer comprising at least one catechol functional end group; and an effective amount of at least one oxidizing reagent, wherein the at least one oxidizing reagent reacts with the modified antifouling polymer to provide a modified antifouling polymer comprising at least one oxidized catechol end group, wherein an antifouling hydrogel is provided. Methods of synthesis, methods of use and kits of the antifouling hydrogel are also provided. | 03-03-2011 |
20110052789 | Composite Structure Including A Low Vinyl Acetate Layer - A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer. | 03-03-2011 |
20110076384 | SYSTEM AND METHOD FOR MAKING BIOMATERIAL STRUCTURES - A system and method for making a biomaterial device includes a support structure providing a shape for a biomaterial device. At least one applicator has a supply of biomaterial solution and is positioned along the support structure. The at least one applicator forms a biomaterial fiber by applying shear force to the biomaterial solution and delivering the biomaterial fiber to the support structure. A controller causes relative movement between the support structure and the at least one applicator, and the biomaterial fiber is arranged on the support structure according to the relative movement to form the biomaterial device. The biomaterial may be silk fibroin which may be wound onto a reciprocating and rotating mandrel. Control over the properties of the biomaterial device is achieved through appropriate selection of material processing, winding strategy, and post-winding processing. | 03-31-2011 |
20110117266 | Medical Device Coating System - A system for coating a medical device comprises a transfer web, a metering web. The webs are each advanced in a downstream direction toward a gap defined by the advancing webs. A coating solution applicator is configured to apply a coating solution at a staging area at a position upstream of the gap. A medical device retaining mechanism is positioned at a coating application area of the transfer web, at a position downstream from the gap. | 05-19-2011 |
20110177230 | MEDICAL GUIDE WIRE AND PROCESS FOR PRODUCTION THEREOF - A medical guide wire ( | 07-21-2011 |
20110189377 | Coating for Medical Devices Comprising An Inorganic or Ceramic Oxide and a Therapeutic Agent - The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable medical device, such as an intravascular stem, having a coating comprising an inorganic or ceramic oxide, such as titanium oxide, and a therapeutic agent. | 08-04-2011 |
20110200738 | System and Method for Conditioning Implantable Medical Devices - A method for passivating a biomaterial surface includes exposing the biomaterial surface to therapeutic electrical energy in the presence of blood or plasma. The biomaterial surface may be removably secured within a chamber of a treatment system, which communicates the therapeutic electrical energy to the biomaterial surface while interfacing the biomaterial surface with blood or plasma. | 08-18-2011 |
20110223314 | EFFICIENT MICROENCAPSULATION - A device and method for generating microcapsules employs an inertial-focusing channel for introducing particles dispersed in a prepolymer suspension fluid, a droplet-generating junction for introducing oil evenly onto the flow of particles to create separated droplets of prepolymer suspension fluid encapsulating respective particles in a streamline flow, and a polymerization section for exposing the droplets to UV light or heat to cause polymerization of a polymer coating on separate microcapsules each containing a respective particle. Preferred suspension fluids may be aqueous solution of poly(ethylene-glycol)-diacrylate (PEGDA), or poly(N-isopropyl-acryalmide) (PNIPAAM). The preferred device may employ a curved or linear inertial-focusing microchannel. Functional tags and/or handles may be added to the microcapsules allowing easy detection, measurement and handling of the microcapsules. | 09-15-2011 |
20110281019 | Direct Fluid Coating Of Drug Eluting Balloon - A system and method for coating an expandable member of a medical device comprises providing a dispenser in fluid communication with a fluid source with the dispenser having at least one outlet to dispense fluid of the fluid source therefrom. The outlet(s) of the dispenser is positioned proximate a surface of an expandable member, with relative movement between the outlet(s) and the surface of the expandable member established along a coating path, and fluid is dispensed from the dispenser to form a substantially continuous bead of fluid between the at least one outlet and the surface of the expandable member along the coating path, and simultaneously drying the fluid while dispensing the fluid from the dispenser to control flow of fluid on the surface of the expandable member. The fluid source can include a variety of therapeutic agents. | 11-17-2011 |
20110281020 | Maintaining A Fixed Distance During Coating Of Drug Coated Balloon - A system and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and a dispenser positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A guide maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the expandable member relative to the at least one outlet. | 11-17-2011 |
20110287167 | CERAMIC COATING AND METHOD OF PREPARATION THEREOF - A ceramic coating with gradient density/porosity and/or incorporated biologically active agents can be fabricated on the surface of substrates, including the surface of implantable medical devices. | 11-24-2011 |
20120076919 | METHOD FOR PRODUCING AN ANTIMICROBIAL COATING ON A TECHNICAL SURFACE - The invention relates to a method for producing a microbial substance-releasing layer on a technical surface. The inventive method comprises three steps: a) producing a solution from polyvinylacetate, a preservative agent and a solvent, b) applying the solution to the technical surface, and c) drying the solution applied to the technical surface while forming the layer. The inventive method is characterized by using benzoic acid, sorbic acid, natamycin, bacteriocines, plant extracts or mixtures thereof as the preservative agent and an ethanol/water mixture, ethyl acetate or acetone as the solvent. | 03-29-2012 |
20120076920 | LOCAL DELIVERY OF WATER-SOLUBLE OR WATER-INSOLUBLE THERAPEUTIC AGENTS TO THE SURFACE OF BODY LUMENS - A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue. | 03-29-2012 |
20120094003 | Method Of Making A Sintered Skin Engaging Member - A method of forming a skin engaging member for use on a hair removal device comprising the steps of: providing a carrier having at least one receiving region; applying a skin conditioning composition in a powder form into the receiving region; and sintering the powder to form a solid interconnected network of particles. | 04-19-2012 |
20120094004 | Methods of Forming Self-Supporting Films for Delivery of Therapeutic Agents - The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed. | 04-19-2012 |
20120094005 | Methods of Forming Self-Supporting Films for Delivery of Therapeutic Agents - The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed. | 04-19-2012 |
20120094006 | Method Of Making A Skin Engaging Member - A method of forming a skin engaging member for use on a hair removal device comprising the steps of: providing a carrier having at least one receiving region; and dispensing a skin conditioning composition in a flowable form through a dispensing member, into or onto the receiving region, wherein said skin conditioning composition is dispensed while at least one of said carrier and said dispensing member is moving relative to the other, wherein the skin conditioning composition comprises at least one of: a water soluble polymer, an emollient, and a mixture thereof. | 04-19-2012 |
20120141655 | VAPOR SHEATH FOR LIQUID DISPENSING NOZZLE - The present disclosure provides a device for preventing the fouling of a liquid dispensing nozzle. The end of the dispensing nozzle is placed in a hollow interior of a band carrying the same solvents that are dispensed by the nozzle. The solvent on the band evaporates into a gap between the ring and dispensing nozzle, thus providing a vapor sheath or environment that helps to prevent the fouling of the dispensing nozzle. | 06-07-2012 |
20120183674 | Method of Selectively Applying an Antimicrobial Coating to a Medical Device or Device Material - A process for depositing nanoparticles on a surface. The process includes the steps of: providing a sol including a volatile non-aqueous liquid and nanoparticles suspended in the non-aqueous liquid; processing the sol to form a plurality of droplets; depositing the plurality of droplets on a surface; and evaporating the non-aqueous liquid from the surface leaving a residue of nanoparticles. The liquid can be selected from heptane, chloroform toluene, and hexane and mixtures thereof and the nanoparticles are desirably silver nanoparticles. The plurality of droplets may be formed by a spray process. The surface may be selected from a particular area, region, portion, or dimension of a medical device, device material, packaging material or combinations thereof. The residue of nanoparticles desirably provides antimicrobial properties. | 07-19-2012 |
20120269955 | METHOD FOR THE PRODUCTION OF AN OTOPLASTIC DEVICE - A novel method for producing an otoplastic device is described. In said method, a model of the auditory canal of an individual is made, then a thin film is placed over the model, and said thin film is used for making an accurate copy of the model in a deep drawing process. | 10-25-2012 |
20120276278 | MEDICAL DEVICES HAVING ANTIMICROBIAL COATINGS THEREON - The present invention provides a medical device, preferably a contact lens, which a core material and an antimicrobial metal-containing LbL coating that is not covalently attached to the medical device and can impart to the medical device an increased hydrophilicity. The antimicrobial metal-containing coating on a contact lens of the invention has a high antimicrobial efficacy against microorganisms including Gram-positive and Gram-negative bacterial and a low toxicity, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial metal-containing LbL coating thereon. | 11-01-2012 |
20120321776 | PROCESS FOR IN SITU PLASMA POLYMERIZATION OF SILICONE COATINGS FOR SURGICAL NEEDLES - A novel method of in situ curing of silicone polymer coatings on surfaces of medical devices, such as surgical needles. The method provides for curing the coatings using a plasma. | 12-20-2012 |
20120328768 | APPARATUS AND METHODS FOR MICROPARTICLE DRY COATING OF SURFACES - A device for coating dry powder microparticles onto a surface may include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film. | 12-27-2012 |
20130029029 | BACTIX SILVER-BASED ANTIMICROBIAL ADDITIVE IN BATH AIDS - Compositions for bath aids and other hard surfaces having silver-based antimicrobial efficacy are disclosed. A variety of hard surfaces are suitable for use of the invention. Methods for reducing or eliminating bacterial growth using a silver-based antimicrobial additives in a hard surface are also disclosed. Preferably, the silver-based antimicrobial additive according to the invention may be formed into any desired shape for its desired uses. | 01-31-2013 |
20130084381 | STERILIZATION OF POLYMERIC MATERIALS - A method of sterilizing a polymeric material that is sensitive to radiation. The method includes the steps of applying at least one radiosensitizer to the polymeric material and irradiating the polymeric material with a suitable radiation at an effective dose and time to sterilize the polymeric material. Also disclosed is a method of enhancing the ability of a medical device to withstand sterilization by radiation and a bioabsorbable polymeric medical device. | 04-04-2013 |
20130095226 | METHOD FOR PRODUCING MEDICAL DEVICE - A method for firmly fixing a hydrophilic polymer on a polyamide surface involves applying a solution containing a phenolic compound to a base material of which at least a part of the surface is a polyamide, and coating the base material with a hydrophilic polymer after applying the solution. | 04-18-2013 |
20130122183 | MEDICAL DEVICE COATING APPARATUS AND METHODS OF USE - Apparatus and methods are configured to coat a medical device, such as a stent, with a beneficial medicinal agent using one or more liquid feeds and one or more micromist nozzles. In one implementation, an agent coating rig includes a vertical adjustment means, a rotation means, and a traverse adjustment means for moving a medical device along virtually any point on an x or y axis. In additional or alternative implementations, the agent coating rig can further include a secondary horizontal adjustment means that allows adjustment along virtually any point on a z axis. Furthermore, methods and apparatus are provided for distributing the beneficial agent on the medical device, including delivering the beneficial agent efficiently over time. | 05-16-2013 |
20130129907 | METHOD FOR PRODUCING THIN LAYERS - The invention relates to a method for providing organic, semi-organic, mineral, inorganic and hybrid thin layers and thin layers containing nanoparticles, by simultaneous or alternate spraying of solutions of reactive partners (that is polymer/polymer interacting by hydrogen bonding, polyelectrolyte/small oligo-ion, inorganic compounds, etc.) on the surface of a solid substrate. | 05-23-2013 |
20130129908 | MAGNESIUM-BASED MEDICAL DEVICE AND MANUFACTURING METHOD THEREOF - A magnesium-based medical device which can adjust a degree of corrosion within a wide range of period such that the device can maintain a sufficient strength only during a desired period and disappears within a desired period thereafter and a manufacturing method thereof are provided. A magnesium-based medical device of the present invention is a magnesium-based medical device in which a base material is made of magnesium or a magnesium alloy, wherein a corrosion-resistant film is formed on a surface of the base material, and variation in surface hardness of the formed corrosion-resistant film in the in-plane direction is less than 21 in terms of a dispersion value of Vickers hardness. | 05-23-2013 |
20130142938 | Oriented Collagen Gel - Techniques for the production of flow-oriented collagen gels using hydrodynamics to influence the assembly of collagen fibers. Highly concentrated monomeric solutions of collagen are subjected to shear and extensional flow as they are drawn onto a substrate to induce fibrillogenesis under a high Ph buffer. | 06-06-2013 |
20130156933 | METHOD FOR MANUFACTURING AN ACTIVE FIXATION ELECTRODE - The present invention relates to methods for manufacturing active fixation helices for the stimulation and/or sensing of organs. A first embodiment of a method in accordance with the present invention for making a helix comprises a first step of producing an elongated helix precursor body comprising one or more electrical conductors surrounded by an insulating material. This helix precursor body is then shaped into a helix, material removed in predetermined places in order to expose the areas of the conductors which will be used as electrodes in the final product. The body is coated with an electrically conducting biocompatible coating which is subsequently partly removed in continuous loops from around the electrodes in order to electrically insulate them from each other and to ensure that the electrically active areas of the electrodes are of the correct dimensions. | 06-20-2013 |
20130164435 | METHOD FOR TREATING AN ELASTOMERIC SURFACE OF A DEVICE FOR DISPENSING A FLUID PRODUCT - A method of treating an elastomer surface of a fluid dispenser device, said method comprising a step of modifying at least one elastomer surface to be treated of said device by ionic implantation using multi-charged and multi-energy ion beams, said modified elastomer surface limiting adhesion of the elastomer surfaces during the manufacturing and/or assembly stages, said multi-charged ions being selected from helium (He), nitrogen (N), oxygen (O), neon (Ne), argon (Ar), krypton (Kr), and xenon (Xe), ionic implantation being carried out to a depth of 0 μm to 3 μm. | 06-27-2013 |
20130171329 | PROCESS AND APPARATUS FOR COATING A POROUS SUBSTRATE WITH A COATING LIQUID - An engagement head for engaging a porous substrate includes at least two pin sets, each pin set including a plurality of pins arranged in a plurality of parallel pin rows at a predetermined pin angle, wherein pins of immediately neighboring pin rows are arranged such that pin angles for the pins in a pin row are inversely symmetrical to pin angles for the pins in a neighboring pin row. The pins of a pin row move collectively in the same direction when a pin set is extended, which direction is determined by the pin angle of the pin row, whereby neighboring pin rows move in opposite longitudinal directions from one another when the pin set is extended. The pin sets may be extended and retracted in unison by a single actuation source. | 07-04-2013 |
20130196052 | ANTIMICROBIAL/ANTIBACTERIAL MEDICAL DEVICES COATED WITH TRADITIONAL CHINESE MEDICINES - An antimicrobial composition for coating a medical device. The antimicrobial composition includes a polymeric film forming material and an antimicrobial agent comprising a material selected from the group of extract of | 08-01-2013 |
20130209659 | Buttress Composition - A tissue buttress is provided on at least a first and second jaw of a surgical stapling apparatus. The tissue buttress comprises an electrophilic component and a nucleophilic component. At least a portion of the tissue buttress may be disposed within either or both of the staple pockets and staple forming pockets, securing the tissue buttress to at least one of the staple jaws. | 08-15-2013 |
20130295272 | Granules of a Brittle Material for Room Temperature Granule Spray in Vacuum, and Method for Forming a Coating Film Using Same - The present invention relates to granules of a brittle material for room-temperature granule spray in vacuum, and to a method for forming a coating film using same. Particularly, particles having a size of 0.1 to 6 μm are granulated and a coating film may be formed through room-temperature granule spray in vacuum using the granules. The granules of the brittle material according to exemplary embodiments may be used through the vacuum granule injection at room temperature and a coating process may be continuously performed. Since the granules injected through a nozzle have a relatively large mass and thus have a large amount of kinetic energy, the coating film may be formed at a low gas-flow rate, and the forming rate of the coating film may be increased. Therefore, the granules may be useful for forming a ceramic coating film. | 11-07-2013 |
20130323402 | TISSUE REPAIR AND REPLACEMENT - Tissue fixation devices are provided. The devices include a first component and a second component, the components having different rates of in vivo degradation. The first component and second component are arranged so that, upon degradation of one of the components, the other component provides a scaffold into which bone can grow. | 12-05-2013 |
20130330464 | METHOD OF MAKING SELF-CLEANING SKIN-LIKE PROSTHETIC POLYMER SURFACES - An external covering and method of making an external covering for hiding the internal endoskeleton of a mechanical (e.g., prosthetic) device that exhibits skin-like qualities is provided. The external covering generally comprises an internal bulk layer in contact with the endoskeleton of the prosthetic device and an external skin layer disposed about the internal bulk layer. The external skin layer is comprised of a polymer composite with carbon nanotubes embedded therein. The outer surface of the skin layer has multiple cone-shaped projections that provide the external skin layer with superhydrophobicity. The carbon nanotubes are preferably vertically aligned between the inner surface and outer surface of the external skin layer in order to provide the skin layer with the ability to transmit heat. Superhydrophobic powders may optionally be used as part of the polymer composite or applied as a coating to the surface of the skin layer to enhance superhydrophobicity. | 12-12-2013 |
20130344229 | SURFACE-INDEPENDENT, SURFACE-MODIFYING, MULTIFUNCTIONAL COATINGS AND APPLICATIONS THEREOF - The present invention provides a surface-independent surface-modifying multifunctional biocoating and methods of application thereof. The method comprises contacting at least a portion of a substrate with an alkaline solution comprising a surface-modifying agent (SMA) such as dopamine so as to modify the substrate surface to include at least one reactive moiety. In another version of the invention, a secondary reactive moiety is applied to the SMA-treated substrate to yield a surface-modified substrate having a specific functionality. | 12-26-2013 |
20130344230 | METHOD OF MANUFACTURING A GUIDEWIRE WITH AN EXTRUSION JACKET - A method of manufacturing a guidewire having a discrete length. The method includes the steps of feeding a first end of a corewire into an extrusion device, gripping the first end of the corewire with a gripping apparatus, and extruding a first extrusion material onto an outer surface of the corewire while the gripping apparatus pulls the corewire through the extrusion device to form an extrusion jacket on the outer surface of the corewire. The corewire has a predetermined length corresponding to a length of the guidewire. | 12-26-2013 |
20140004250 | Methods of treatment of polymeric coatings for control of agent release rates | 01-02-2014 |
20140017391 | DEVICE FOR COATING INTRAMEDULLARY RODS WITH CEMENT - A mold for forming a coated intramedullary (IM) nail can include a tubular member having an insertion end and an opposite end. The tubular member can comprise a sidewall extending along a longitudinal axis between an outer surface and an inner surface. The sidewall can define at least one threaded inlet port therealong. The tubular member can be configured to receive the IM nail therein. The tubular member can be further configured to locate a flowable material against the IM nail within the inner surface. | 01-16-2014 |
20140037831 | Coating Layers For Medical Devices And Method Of Making The Same - Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents. | 02-06-2014 |
20140037832 | Coating Layers For Medical Devices And Method Of Making The Same - Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents. | 02-06-2014 |
20140072694 | ROTATIONAL SPUN MATERIAL COVERED MEDICAL APPLIANCES AND METHODS OF MANUFACTURE - A medical appliance or prosthesis may comprise one or more layers of rotational spun nanofibers, including rotational spun polymers. The rotational spun material may comprise layers including layers of polytetrafluoroethylene (PTFE). Rotational spun nanofiber mats of certain porosities may permit tissue ingrowth into or attachment to the prosthesis. Additionally, one or more cuffs may be configured to allow tissue ingrowth to anchor the prosthesis. | 03-13-2014 |
20140161964 | COATING APPARATUS AND METHODS - Embodiments of the invention include coating apparatuses and related methods. In an embodiment, the invention includes a coating apparatus. The coating apparatus can include a motor, a rotating contact member, a fluid applicator, a fluid pump, and a base member. The fluid applicator can include an orifice. The rotating contact member can be configured to rotate around a device to be coated that does not rotate. The rotating contact member can be configured to move along the lengthwise axis of a device to be coated. In an embodiment, the invention includes a method of coating a medical device. The method of coating a medical device can include a rotating a contact member around the outer diameter of a non-rotating medical device, applying a coating solution to the outer diameter of the non-rotating medical device at a position adjacent to the contact member, and moving at least one of the contact member and the non-rotating medical device with respect to one another so that the contact member moves with respect to the lengthwise axis of the non-rotating medical device. Other embodiments are also included herein. | 06-12-2014 |
20140170298 | DEPOSITION OF A SILVER LAYER ON A NONCONDUCTING SUBSTRATE - Methods for the deposition of silver-comprising films on nonconducting substrates, and, more particularly, to deposition of such films that are very thin, are provided. The surface of nonconducting substrates is modified with a superabsorbent polymer to increase silver deposition when compared to a non-modified surface. Also provided are films produced using a swelling agent, whereby porosity of the surface of the nonconducting substrate is increased, thereby permitting increased silver deposition when compared to an unmodified surface. | 06-19-2014 |
20140255593 | FUSION OF BIOCOMPATIBLE GLASS/CERAMIC TO METAL SUBSTRATE - Applicants have disclosed a process for fusing a biocompatible glass to a metal substrate. In the preferred embodiment, the process comprises: grit blasting a metallic substrate (e.g., titanium) to remove a surface layer of the metal; after blasting, cleaning the abrasion residue off the surface layer; blending a solvent to use as a suspension agent; creating a suspension of glass-coating powders in the solvent solution; depositing the suspension onto the metallic substrate; drying thoroughly the suspension-coated metallic substrate; inserting the dried, coated substrate into a non-reactive chamber, purging the chamber with an inert gas, such as pure argon; and firing the metallic substrate, inside the furnace, in the inert gas. This process forms a robust fusion between the biocompatible glass/ceramic and titanium, according to preliminary test results. This process can be used for various medical and dental devices, including implants and onplants. | 09-11-2014 |
20140272097 | DNA MARKING OF PREVIOUSLY UNDISTINGUISHED ITEMS FOR TRACEABILITY - The invention provides a method of marking an item with a naturally-derived or synthetic non-natural polymeric marker molecules, such as a DNA or Peptide marker in conjunction with optional visible or rapid scan reporters for authenticating or tracking, in which the method includes providing an item for marking, and applying a medium including a DNA marker to the item. The invention also provides a method of marking an item with a DNA marker for authenticating or tracking, in which the method includes providing a medium including a DNA marker, and molding the medium including the DNA marker to provide all or part of the item. The DNA marker encodes information unique to the item and/or the model of the item as desired. | 09-18-2014 |
20140272098 | PROCESS FOR MANUFACTURING NANOPARTICLES IN A CONCENTRATED SLURRY - The present invention concerns a process for manufacturing nanoparticles in a slurry based on an aqueous solvent by treating said inorganic particles or their agglomerates in said solvent at a solids content of 30-75w-%, by adding dispersing agent(s) and by carrying out ultrasonic treatment at an intensity of 5-1000 W/cm | 09-18-2014 |
20140363562 | PHOTO-CURING OF THERMOPLASTIC COATINGS - The present invention relates to a method for the preparation of a medical device element by means of extrusion or injection moulding and to medical devices comprising such extruded or injection moulded medical device elements. The medical device elements (e.g. tubes, wires, lines, stents, catheters, guides, endodontic instruments, needles, trocars for e.g. laparoscopic surgery, laparoscopic accessories, surgical instruments, guide wires) are characterized by a prefabricated shaped article or a thermoplastic substrate polymer having thereon a layer of a covalently cross-linked coating composition of a thermoplastic matrix polymer and a hydrophilic polymer. The method involves a coating composition comprising a thermoplastic matrix polymer, a hydrophilic polymer, and one or more photo-initiator(s), e.g. covalently linked to molecules of the thermoplastic matrix polymer and/or to molecules of the hydrophilic polymer. The coating composition is irradiated with UV or visible light so as to covalently cross-link said coating composition. | 12-11-2014 |
20140370182 | ORGANIC SILICON COMPOUND AND SILANE COUPLING AGENT CONTAINING THE SAME - There is provided a novel organic silicon compound that can be used for a silane coupling agent. An organic silicon compound of Formula (1): | 12-18-2014 |
20150072066 | Antimicrobial Silver Compositions - The present invention comprises methods and compositions for antimicrobial silver compositions comprising silver nanoparticles. The present invention further comprises compositions for preparing silver nanoparticles comprising at least one stabilizing agent, one or more silver compounds, at least one reducing agent and a solvent. In one aspect, the stabilizing agent comprises a surfactant or a polymer. The polymer may comprise polymers such as polyacrylamides, polyurethanes, and polyamides. In one aspect, the silver compound comprises a salt comprising a silver cation and an anion. The anion may comprise saccharinate derivatives, long chain fatty acids, and alkyl dicarboxylates. The methods of the present invention comprise treating devices with the silver nanoparticle compositions, including, but not limited to, such devices as woven wound care materials, catheters, patient care devices, and collagen matrices. The present invention further comprises treatment of humans and animals wacr6ith the antimicrobial devices described herein. | 03-12-2015 |
20150079270 | Fabrication of Magnetic Nanoparticles - Methods for forming core-shell magnetic nanoparticles are provided. The method can include: forming an oxide shell around a metal oxide core to form a core-shell magnetic nanoparticle; attaching an anchoring agent to the magnetic nanoparticle; reacting a RAFT agent with the functional group of the anchoring agent such that the RAFT agent is bonded to the magnetic nanoparticle through the anchoring agent; and attaching a polymeric chain to the RAFT agent. | 03-19-2015 |
20150118388 | MARKED PRECOATED MEDICAL DEVICE AND METHOD OF MANUFACTURING SAME - A medical device, such as a medical wire, which includes a coating applied to the surface of the medical wire. The coating includes a base layer bonded to the surface of the medical wire and an at least partially transparent low-friction top coat applied to the base layer. The base layer includes heat activated pigments that change color when heated above a color shifting temperature. In one embodiment, the color of the pigment in one area contrasts with the color of the pigment in an adjacent area without otherwise affecting the low-friction surface of the coating. The areas of different color created in locations along the length of the low-friction coated medical wire form markings which, as an example, enable a surgeon to determine the length of the medical wire inserted into a body by observing the markings on the portion of the marked medical wire located exterior to the body. | 04-30-2015 |
20150132468 | METHOD OF MAKING A COATED WIRE GUIDE - In a method for making a wire guide, a fluoropolymer coating is removed from a distal section of an FP coated core wire to expose a metallic portion. A polymer coating is applied to a proximal section of the FP coated core wire such that the polymer coating overlays at least a portion of the FP coating, and to the distal section of the FP coated core wire including the exposed metal portion. The polymer coating is removed from the FP coating to form the wire guide having a proximal portion with the FP coating and a distal portion with the polymer coating. A hydrophilic coating may be applied to the distal portion over the polymer coating. | 05-14-2015 |
20150366213 | INORGANIC COATING AND COMPOSITION - This disclosure relates to basic inorganic compositions. Methods of providing antifungal/antibacterial resistance and/or hydrophobicity and/or corrosion resistance by coating surfaces with the basic inorganic compositions are provided. In another aspect, a silicate composition comprising at least one alkali earth metal; and a Group IV element of silicon, germanium, tin, or lead having at least one hydrocarbon moiety covalently bonded thereto is provided. | 12-24-2015 |
20150374886 | COATINGS WITH CRYSTALLIZED ACTIVE AGENT(S) AND METHODS - The present invention relates to coatings with crystallized active agent(s) and related methods. In an embodiment, the invention includes a method for coating a medical device including selecting a solvent and a polymer, selecting a concentration of an active agent of at least a certain amount of saturation, forming a coating composition having the selected concentration of the active agent, and applying the coating composition to the medical device. In an embodiment, the invention includes an elution control coating disposed on a medical device, the elution control coating including a polymer, and an active agent, wherein the active agent is at least about 80% crystallized within one week of being disposed on the medical device. In an embodiment, the invention includes a method for enhancing the formation of active agent crystals within a coating layer including forming a coating solution and adjusting the concentration of the active agent in the coating solution to reach some percentage of the active agent saturation point. In an embodiment, the invention includes a method of enhancing crystallization of an active agent, the method including forming a coating solution comprising a polymer, an active agent, and a solvent; applying the coating solution to a substrate; and increasing the rate of active agent nucleation within the coating. | 12-31-2015 |
20160022882 | MEDICAL IMPLEMENTS AND MEDICAL IMPLEMENT PRODUCTION METHODS - The present disclosure provides medical implements having films fixed to at least a portion of their surface. In embodiments, a medical implement of the present disclosure may include a substrate including a synthetic resin, a film including a methyl vinyl ether-maleic anhydride copolymer in combination with a polyether block amide fixed to at least a portion of a surface of the substrate, and a silver ion bound to the film. Methods for forming such medical implements are also provided. | 01-28-2016 |
20160030732 | PACING LEADS WITH A STRUCTURED COATING - An implantable medical device includes a lead body having a distal end and a proximal end, a lumen and at least one lead wire extending through the lumen. The lead wire has an outer surface and a polymeric coating on at least a portion of the outer surface of the lead wire. The coating includes a first structure having a first end proximate the outer surface of the lead wire and a second end opposite the first end. The second end is movable relative to the first end and relative to the lead wire. | 02-04-2016 |
20160038902 | PATTERNED DEPOSITION OF LIQUID FILMS FOR BIOMEDICAL DEVICES - Embodiments described herein generally relate to a method for deposition of a biofunctionalizing material, such as for the production of a biomedical device. The method can include positioning a substrate on a substrate support, the substrate having a plurality of wells formed therein. A printing mask is positioned over the substrate, the printing mask having a plurality of mask openings, the plurality of mask openings corresponding to the plurality of wells. A biofunctionalizing material is then deposited through the printing mask and into the wells, the biofunctionalizing material being guided by the plurality of mask openings, the biofunctionalizing material forming a layer over a bottom surface of the plurality of wells. | 02-11-2016 |
20160058920 | Method for Treating Surface of Implant - Disclosed is a method for treating a surface of an implant. The disclosed method for treating the surface of the implant comprises the steps of: coating a surface treatment composition containing an organic material having a hydrophilic group on the surface of the implant (coating step); and drying the coated surface treatment composition (drying step). | 03-03-2016 |
20160089479 | ELECTRODEPOSITION COATING FOR MEDICAL DEVICES - The present disclosure relates generally to coating medical devices. In particular, the present disclosure provides materials and methods for coating a portion of a balloon catheter with a pharmaceutical agent using electrodeposition techniques. Although angioplasty and stenting can be effective methods for treating vascular occlusions, restenosis remains a pervasiveness problem. Therefore, coating portions of a balloon catheter with a pharmaceutical agent that inhibits restenosis can reduce the likelihood of restenosis. | 03-31-2016 |
20160101219 | METHODS AND PROCESSES FOR APPLICATION OF DRUG DELIVERY POLYMERIC COATINGS - Polymeric coatings, their applications, and the methods of their preparation are described. The coatings may be used to confer desirable properties to the consumer and/or medical products. Also described are methods of loading therapeutic agents on the polymeric coatings and the applications of the drug eluting polymeric coatings thus obtained. | 04-14-2016 |
20160175494 | Medical Devices for Delivering a Bioactive to a Point of Treatment and Methods of Making Medical Devices | 06-23-2016 |
20160184494 | PROHEALING PIEZOELECTRIC COATINGS - Provided herein is a prohealing piezoelectric coating and the method of making and using the same. | 06-30-2016 |
20160199542 | Pharmaceutical-Coated Medical Products, the Production Thereof and the Use Thereof | 07-14-2016 |
20160250391 | COATING LAYER, COATING SOLUTION, METHOD FOR FORMING COATING LAYER, AND METHOD FOR PRODUCING MEDICAL TOOL | 09-01-2016 |