Entries |
Document | Title | Date |
20080200528 | Derivatives of a 1-Phenyltriazole - Compounds of formula (I) | 08-21-2008 |
20080249149 | Crystalline Forms of Rizatriptan Benzoate - The present invention is directed to the novel polymorphic Form A and Form B of Rizatriptan benzoate, processes for the preparation thereof and pharmaceutical compositions comprising these crystalline forms. | 10-09-2008 |
20080249150 | HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION CONTAINING AN AZOLE - Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia: | 10-09-2008 |
20080255216 | Diaryltriazoles as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 - 2,5-Diaryl-1,2,4-triazole derivatives of structural formula I are selective inhibitors of the 11&bgr;-hydroxysteroid dehydrogenase Type 1 enzyme (11&bgr;-HSD-1). The compounds are useful for the treatment of diabetes, hyperglycemia, obesity, insulin resistance, atherosclerosis, dyslipidemia, hyperlipidemia, hypertension, and Metabolic Syndrome. Also disclosed are novel compounds of structural formula II which are inhibitors of 11&bgr;-HSD-1. | 10-16-2008 |
20080262060 | Crystalline forms of Deferasirox - The present invention provides novel crystalline forms of deferasirox, methods for their production, and methods for conversion of the novel forms to the known crystalline form I. | 10-23-2008 |
20080262061 | COMPOSITION AND USE OF A LIQUID FUNGICIDAL FORMULATION OF MYCLOBUTANIL OR TEBUCONAZOLE FUNGICIDE - A fungicide composition containing a fungicide compound and a surfactant, wherein the fungicide is fully dissolved in the surfactant, and wherein the fungicide is selected from either myclobutanil or tebuconazole or a mixture thereof. | 10-23-2008 |
20080275097 | Non-nucleoside reverse transcriptase inhibitors - Compounds of Formula I: | 11-06-2008 |
20080287512 | Plant Protection Composition Including an Active Compound Selected from Azoles and a Solvent, and Useful Solvent Composition - The present invention relates to a concentrated plant protection composition containing an active compound selected from azoles and preferable triazoles such as tebuconazole. The composition contains at least one solvent. The composition is stable and easy for farmers to use. The present invention further relates to a useful solvent composition particularly suitable for implementing the plant protection composition. | 11-20-2008 |
20080293792 | Tocopherol derivatives and uses thereof - Tocopherol derivatives having the general formula: | 11-27-2008 |
20080293793 | Fungicidal Mixtures for Wood Preservation - Using synergistically effective mixtures comprising triadimefon and/or triadimenol and at least one further known fungicidally active compound, it is possible to protect industrial materials, in particular wood, against attack, damage and/or destruction by biological pests, in particular by wood-destroying fungi. | 11-27-2008 |
20080293794 | DIARYLTRIAZOLMETHYLAMINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF - The invention concerns compounds of formula (I): | 11-27-2008 |
20080312302 | Desferasirox Dispersible Tablets - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet. | 12-18-2008 |
20080319037 | 1,2,4-TRIAZOL-1-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMORS - There is provided a compound of Formula I | 12-25-2008 |
20090030053 | FUNGICIDAL COMPOSITIONS - The invention relates to a composition capable of controlling phytopathogenic fungi on a plant or propagation material thereof said composition comprising as active ingredients a mixture of: (A) Difenoconazole or a salt or metal complex thereof; and (B) Chlorothalonil, wherein said Difenoconazole or the salt or metal complex thereof and said Chlorothalonil are present in said composition in amounts which produce a synergistic effect. The composition of the invention is also suitable for the protection of industrial materials. | 01-29-2009 |
20090030054 | CYTOPLASMIC ANTIGENS FOR DETECTION OF CANDIDA - The present invention relates to a method and a means of diagnosing | 01-29-2009 |
20090036507 | BIS (CYANOPHENYL) METHYL-TRIAZOLE FOR USE IN PREVENTION OF BREAST CANCER - The present invention relates to the use of a lower dosage of bis(cyanophenyl)methyl-triazole of the formula (I) or a pharmaceutically acceptable salts thereof, for the preparation of a pharmaceutical composition for the prevention of conditions responsive to aromatase inhibition and to inhibition of estrogen biosynthesis, especially breast cancer, in mammals. | 02-05-2009 |
20090042963 | Triazole-Based Fungicidal Mixtures - Fungicidal mixtures, comprising | 02-12-2009 |
20090048319 | Method of Using a Micronutrient as Safener for a Triazole for Controlling Harmful Fungi - A method of using a micronutrient selected from the group consisting of salts and adducts of Mg, Ca, B, Mn, Fe, Co and Zn and Mo as a safener for a triazole, selected from the group consisting of azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, enilconazole, epoxiconazole, fenbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, tebuconazole, tetraconazole, triadimenol, triadimefon and triticonazole or salts or adducts thereof for controlling harmful fungi. | 02-19-2009 |
20090062357 | DEUTERIUM-ENRICHED FLUCONAZOLE - The present application describes deuterium-enriched fluconazole, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-05-2009 |
20090082412 | DEUTERIUM-ENRICHED DEFERASIROX - The present application describes deuterium-enriched deferasirox, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-26-2009 |
20090082413 | DEUTERIUM-ENRICHED LETROZOLE - The present application describes deuterium-enriched letrozole, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-26-2009 |
20090082414 | DEUTERIUM-ENRICHED VIRAMIDINE - The present application describes deuterium-enriched viramidine, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 03-26-2009 |
20090111862 | Compound - There is provided a compound of Formula I | 04-30-2009 |
20090111863 | Compounds, Compositions and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of β-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment. | 04-30-2009 |
20090124678 | Combined Use of Metconazole and Epoxiconazole for Reducing or Preventing the Contamination of Cereals With Mycotoxins - The invention relates to the combined use of metconazole and epoxiconazole for reducing or preventing the contamination of cereals with mycotoxins formed by mould fungus producing trichothecene. | 05-14-2009 |
20090137649 | Concentrated liquid triazole-fungicide formulations - Concentrated liquid formulations of triazole fungicides are provided and the use of such formulations in diluted form for the control of harmful fungi. The formulations are both storage stable and prevent crystallization of the triazole fungicide when applied in diluted form. | 05-28-2009 |
20090163564 | Translational Dysfunction Based Therapeutics - Provided are methods and compositions for inhibiting eukaryotic translation initiation factor eIF4E. Such methods and compositions may be used alone or in conjunction with other therapies, such as gene therapies, for inhibiting cell proliferation and/or treating cancer. | 06-25-2009 |
20090170918 | Solid Formulation of Fungicidal Mixtures - The invention provides highly concentrated WG formulations of fungicidal mixtures, comprising
| 07-02-2009 |
20090186928 | Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1 - Novel crystalline salts of 3-[1-(4-chlorophenyl)-trans-3-fluorocyclobutyl]-4,5-dicyclopropyl-r-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment. | 07-23-2009 |
20090197929 | Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds - The present invention relates to azolylmethyloxiranes of the general formula I | 08-06-2009 |
20090215845 | Fungicidal mixtures - Synergistically effective mixtures comprising prochloraz and tebuconazole and fungicidal compositions based thereon are highly suitable for protecting industrial materials, in particular wood and timber products, against attack, damage and/or destruction by biological pests. | 08-27-2009 |
20090247597 | AGROCHEMICAL FORMULATIONS THAT CAN BE DISPERSED IN WATER CONTAINING POLYALKOXYTRIGLYCERIDED AS PENETRATION ENHANCES - The present invention relates to novel water-dispersible agrochemical formulations such as, for example, water-based suspension concentrates and water-dispersible granules of agrochemically active compounds comprising a penetrant from the class of the polyalkoxytriglycerides, to a process for preparing these formulations and to their use for applying the active compounds comprised therein. | 10-01-2009 |
20090270471 | METHOD FOR INHIBITING MYCOTOXIN PRODUCTION - The present invention provides a method for prominently inhibiting the production in fungi of mycotoxin, which has serious effects on health of humans and other animals, and provides a mycotoxin production inhibitor. Mycotoxin content such as deoxinivalenol (DON) in harvested crops can be reduced without a correlation with the control effects against fungi by spraying a fungicide containing a benzimidazole-type fungicidal compound such as thiophanate-methyl as an active ingredient onto food crops such as wheat, barley, and the like. Concomitant use of the benzimidazole-type fungicidal compound and a sterol biosynthesis inhibitor (SBI agent) such as tebuconazole can further enhance the effect. | 10-29-2009 |
20090291994 | Use of Pyraclostrobin as Safener for Triticonazole for Controlling Harmful Fungi - (1) Use of pyraclostrobin of the formula I | 11-26-2009 |
20090306160 | METHODS FOR IMPROVING DRUG DISPOSITION - The invention provides a method for improving the bioavailability, preferably, oral bioavailability and/or drug disposition, e.g. brain penetration, of an iron chelator, which method comprises co-administering to a mammal, especially a human, in need of such treatment, a combination of an iron chelator and an efflux protein inhibitor. | 12-10-2009 |
20100004303 | TREATMENT OF ENDOCRINE DYSFUNCTION USING IRON CHELATORS - The invention relates to the use of an iron chelator for the treatment or prevention of pathologies due to iron loading, e.g. related to a dysfunction, in particular a reduction or inhibition, of the secretory function of cells from endocrine glands, in the human or animal body. | 01-07-2010 |
20100048655 | Comb Polymers and Use Thereof for the Production of Active or Effective Ingredient Formulations - The present invention relates to novel comb polymers, to a process for their manufacture and to the use thereof in the stabilization in an aqueous phase of active or effect substances which are insoluble or sparingly soluble in water. The invention furthermore relates to the use of the comb polymers in the manufacture of active substance formulations or active substance preparations of water-insoluble active or effect substances, in particular of active substances for plant protection. | 02-25-2010 |
20100056590 | POLYMORPHIC FORMS OF DEFERASIROX (ICL670A) - The invention relates to crystalline forms of -[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid and to its amorphous form, to processes for the preparation thereof, to compositions containing the same and their uses for the manufacture of a medicament for the treatment of the human body. | 03-04-2010 |
20100099724 | Formulations Comprising Triazoles and Alkoxylated Amines - The present invention relates to the use of alkoxylated amines to enhance the activity of fungicidal formulations comprising fungicidal triazoles. It also relates to formulations comprising one or more fungicidal triazoles and alkoxylated amines. These formulations are useful for the protection of any living or non-living material, such as crops, plants, fruits, seeds, objects made of wood, thatch or the like, biodegradable material and textiles against deterioration due to the action of fungi. | 04-22-2010 |
20100113542 | TRIAZOLE DERIVATIVE AS AN HSP 90 INHIBITOR - 5-[4-(2-Methylphenyl)-3-hydroxy-4H-1,2,4-triazol-5-yl]-2,4-dihydroxy-N-methyl-N-butylbenzamide is an HSP90 inhibitor and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role. | 05-06-2010 |
20100113543 | Crystalline Complexes of Agriculturally Active Organic Compounds - The present invention relates to crystalline complexes comprising at least one agriculturally active organic compound A having at least one functional moiety which is capable as serving as a hydrogen acceptor in a hydrogen bond and thiophanate-methyl. | 05-06-2010 |
20100120878 | FORMULATION - This invention relates to mixtures of triazole compounds and in particular to the use of such mixtures in non-crystallising compositions. It relates to mixtures that are concentrated solutions and also to the use of the concentrated solutions in water diluted form. Furthermore, it relates to the use of such mixtures for agricultural or materials protection purposes and to the use of one triazole compound to prevent or delay crystallisation of a second triazole compound. | 05-13-2010 |
20100120879 | INSECTICIDES AS SAFENER FOR FUNGICIDES WITH PHYTOTOXIC ACTION - The present invention relates to the use of insecticides which are selected among GABA antagonists and nicotin receptor agonists/antagonists, if appropriate in combination with at least one gibberellin, as safener for fungicides which have a phytotoxic effect. Moreover, the invention relates to a method of reducing or preventing the phytotoxic effect of fungicides on plants treated therewith or on plants whose seeds or growth substrate have been or are treated with these fungicides. The invention finally also relates to compositions which comprise at least one GABA antagonist, at least one azole fungicide or strobilurin fungicide and, if appropriate, at least one gibberellin, and to compositions which comprise at least one nicotin receptor agonist/antagonist, at least one azole fungicide or strobilurin fungicide and, if appropriate, at least one gibberellin. | 05-13-2010 |
20100144812 | Heterocyclic Sulfonamide Inhibitors of Beta Amyloid Production Containing an Azole - Compounds useful for lowering beta amyloid levels are provided. The compounds have the structure of formula Ia: | 06-10-2010 |
20100152261 | NOVEL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND - A nitrogen-containing heterocyclic derivative represented by the following general formula (I), or a hydrate or solvate thereof, which has a selective antagonistic action on the muscarinic M | 06-17-2010 |
20100173963 | COMPOUND - There is provided a compound of Formula I | 07-08-2010 |
20100173964 | PHARMACEUTICAL COMPOSITION THAT INCLUDES A DIPEPTIDYL PEPTIDASE-IV INHIBITOR - The present patent application relates to a pharmaceutical composition for oral administration that includes a certain pyrrolidine derivative as DPP-IV inhibitor, and a pharmaceutically acceptable excipient. More particularly, the present invention contemplates pharmaceutical compositions that include melogliptin and a pharmaceutically acceptable excipient as well as to processes for preparing the pharmaceutical composition and the use of the composition in reducing glucose level in a subject. The present invention also contemplates an impurity associated with melogliptin. | 07-08-2010 |
20100179204 | CO-CRYSTALS OF PROPICONAZOLE - The present invention relates to co-crystals of propiconazole and a co-crystal forming compound. | 07-15-2010 |
20100184815 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA - Disclosed are compounds of the formula: | 07-22-2010 |
20100184816 | Method for Reducing the Phytotoxicity of Azoles on Dicotyledonous Plants by Adding Additives - The present invention relates to a method for reducing the phytotoxicity of azoles on dicotyledonous plants by addition of additives. Furthermore, the application relates to novel compositions comprising certain triazole fungicides in combination with additives, in particular alkali metal sulphosuccinates, and their use for controlling unwanted phytopathogenic fungi. | 07-22-2010 |
20100197749 | CHEMICAL COMPOUNDS - The invention relates to chemical compounds of formula (I) and (II): | 08-05-2010 |
20100222400 | F1F0-ATPase Inhibitors and Related Methods - The present invention relates to a family of guanidine-based F1F0-ATPase inhibitors, e.g., mitochondrial F1F0-ATPase inhibitors, methods for their discovery, and their use as therapeutic agents for treating certain disorders. | 09-02-2010 |
20100298394 | ANTIFUNGAL AGENTS AS NEUROPROTECTANTS - Provided herein are compounds, compositions and methods for protecting neuronal and glial cells. | 11-25-2010 |
20100331380 | Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of β-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment. | 12-30-2010 |
20100331381 | Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands - The invention relates to substituted phenylureas and phenylamides, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions. | 12-30-2010 |
20110003872 | MATERIAL FORMED FROM DENDRITIC MOLECULES CONTAINING ASSOCIATIVE GROUPS - The present invention relates to a material comprising dendritic molecules each constituted of fragments that are at least bifunctional and of fragments that are at least trifunctional joined together by ester or thioester bridges, alone or in combination with amide or urea bridges, said bridges being formed from two functions carried by different fragments, said molecules containing, on the fragments located at the ends of the dendritic branches, associative end groups capable of forming associations with one another by hydrogen bonds and joined covalently to the functions that are not involved in said bridges. It also relates to the method of production thereof, as well as to its uses and to compositions, notably cosmetic, containing this material. | 01-06-2011 |
20110021586 | PHENYL-SULFAMATES AS AROMATASE INHIBITORS - There is provided a compound of Formula I | 01-27-2011 |
20110039904 | Alcohol alkoxylates, agents comprising the same and use of the alcohol alkoxylates as adjuvants in the agrochemical field - The present invention relates to certain alcohol alkoxylates of the amphiphilic type, to agrochemical agents comprising them, and to the use of the alcohol alkoxylates as activity-improving adjuvants in the agrochemical field and particularly in the field of plant protection. The alcohol alkoxylates are alkoxylated alcohols of the formula (I) | 02-17-2011 |
20110046193 | DEFERACIROX DISPERSIBLE TABLETS - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet. | 02-24-2011 |
20110053996 | Use of phenyltriazoles for controlling insects and spider mites by watering, droplet application or dip application or by treating seed - The present invention relates to the use of compounds of the formula (I) | 03-03-2011 |
20110065766 | METHODS OF USE OF ANTIVIRAL COMPOUNDS - The present invention relates, in part, to methods of treatment, prevention, and inhibition of viral disorders. In one aspect, the present invention relates to inhibition of the M2 proton channel of influenza viruses (e.g. influenza A virus) and other similar viroporins (e.g., VP24 of Ebola and Marburg viruses; and NS3 protein of Bluetongue). The present invention further relates, inter alia, to compounds which have been shown to possess antiviral activity, in particular, inhibiting the M2 proton channel of influenza viruses. | 03-17-2011 |
20110071201 | PHENOL-CONTAINING AZOLE COMPOSITIONS FOR THE PROTECTION OF INDUSTRIAL MATERIALS - Composition, comprising
| 03-24-2011 |
20110092556 | PLANT DISEASE CONTROLLING COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE - There is provided a plant disease controlling composition comprising at least one compound (A) selected from the group consisting of metconazole, bromuconazole and epoxyconazole, as well as a compound represented by the formula (I): as active ingredients. Also provided is a method for controlling a plant disease, which comprises applying at least one compound (A) selected from the group consisting of metconazole, bromuconazole and epoxyconazole, as well as the compound represented by the formula (I) to a plant, a seed of a plant or a cropland. | 04-21-2011 |
20110105575 | METHOD OF TREATMENT OF HEREDITARY HEMOCHROMATOSIS - The present invention relates to the use of Compound I of the following formula | 05-05-2011 |
20110105576 | PESTICIDAL COMBINATIONS - A method of controlling or preventing pathogenic damage and/or pest damage in a plant propagation material, a plant, part of a plant and/or plant organ that grow at a later point in time, which comprises applying on the plant, part of the plant, plant organ, plant propagation material or a surrounding area thereof a combination comprising (I) prochloraz, (II) metconazole, and optionally (III) metalaxyl or mefenoxam. | 05-05-2011 |
20110144171 | THIOPENE CONTAINING ANALOGUES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND PROCESS FOR THEIR PREPARATION - The present invention discloses novel compounds of the Formula (1), containing thiophene moieties and pharmaceutically acceptable salts thereof, methods for preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these novel compounds. | 06-16-2011 |
20110190362 | ANTIMICROBIAL COMPOSITION USEFUL FOR PRESERVING WOOD - Antimicrobial compositions useful for preserving wood, and comprising a variety of antimicrobial compounds. | 08-04-2011 |
20110237634 | NOVEL CRYSTALLINE FORMS OF AN INHIBITOR OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 - Novel crystalline salts of 3-[4-(3-ethanesulfonyl-propyl)-bicyclo[2.2.2]oct-1-yl]-4-methyl-5-(2-trifluoromethyl-phenyl)-4H-1,2,4-triazole are potent inhibitors of 11β-hydroxysteroid dehydrogenase Type 1 and are useful for the treatment of conditions associated with Metabolic Syndrome as well as cognitive impairment. The invention also relates to pharmaceutical compositions containing these novel salts, processes to prepare these salts and their pharmaceutical compositions as well as uses thereof for the treatment of Type 2 diabetes, hyperglycemia, obesity, dyslipidemia, hypertension, and cognitive impairment. | 09-29-2011 |
20110245306 | CO-CRYSTALS - The present invention relates to co-crystals of propiconazole and a co-crystal forming compound. | 10-06-2011 |
20110257234 | Agrochemical Auxiliary Compositions - Suggested are agrochemical auxiliary compositions, comprising (a) alkoxylated polyol esters, (b) optionally alkoxylated alk(en)yl oligoglycosides, and (c) fatty acids or their salts. | 10-20-2011 |
20110294861 | METHOD OF TREATMENT OF HEREDITARY HEMOCHROMATOSIS - The present invention relates to the use of Compound I of the following formula | 12-01-2011 |
20110319457 | DEFERACIROX DISPERSIBLE TABLETS - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet. | 12-29-2011 |
20120010259 | Methods of Treating an Overweight or Obese Subject - The invention herein generally relates to methods of treating a subject having an overweight or obese condition, and overweight- or obesity-related conditions. In one embodiment, the invention herein provides a method of treating a subject having an overweight or obese condition involving administering to the subject in need thereof, an amount of a pharmaceutical composition including a MetAP-2 inhibitory compound, or a salt, ester, or prodrug thereof, effective to result in weight loss in the subject. | 01-12-2012 |
20120015993 | Novel Pharmaceutical Forms, and Methods of Making and Using the Same - Crystalline salts, polymorphs, solvates, and hydrates of bicalutamide, 5-fluorouracil, donepezil, anastrozole, nelfinavir, mirtazapine, lansoprazole, and tamsulosin, or derivatives thereof are provided by the subject invention. Methods of making and using the same are also provided. | 01-19-2012 |
20120035230 | Compounds, Compositions, and Methods for the Treatment of Beta-Amyloid Diseases and Synucleinopathies - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment. | 02-09-2012 |
20120071530 | AGROCHEMICAL COMPOSITION AND METHOD FOR PREPARING AND USING THE SAME - An agrochemical composition comprises an azole active ingredient and an N,N-dialkyl long chain alkylamide. The N,N-dialkyl long chain alkylamide is present in sufficient amount to prevent or inhibit the crystallization of the azole derivative during the application of the composition to a locus. Preferred N,N-Dialkyl long chain alkylamide(s) comprised in the composition is/are selected from the group consisting of compounds of the formula (I): in which (a) R | 03-22-2012 |
20120129901 | TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS - Formula (I) and (II). The present invention relates to the use of a new lupane derivative of general formula (I) or (II), or a pharmaceutically acceptable salt, crystal form, complex, hydrate, or hydrolysable ester thereof, for preventing and/or inhibiting tumor growth and for treating cancer and other proliferative diseases, more particularly for treating leukemia, liver, cervical, colon and prostate cancer. The present invention also relates to the synthesis of these compounds and to pharmaceutical compositions which contain them. | 05-24-2012 |
20120149744 | ANTI-MITOTIC ANTI-PROLIFERATIVE COMPOUNDS - Substituted triazole compounds and pharmaceutical compositions thereof are presented. Also presented are methods for treating a pathology linked to a hyperproliferative disorder by administering the substituted triazole compounds to a patient in need thereof. | 06-14-2012 |
20120165378 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions. | 06-28-2012 |
20120190716 | METHODS AND USES OF CYTOCHROME P450 INHIBITORS - Methods are provided for treating or preventing chronic obstructive pulmonary diseases such as emphysema, and fibrotic diseases including heart, liver, kidney and vascular diseases, by administering to a subject a pharmaceutical composition comprising a compound that inhibits cytochrome P450RA or CYP26. | 07-26-2012 |
20120196909 | DEFERACIROX DISPERSIBLE TABLETS - The invention pertains to dispersible tablets comprising as active ingredient 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or pharmaceutically acceptable salt thereof in an amount of from 5 to 40% in weight by weight of the total tablet. | 08-02-2012 |
20120309801 | CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING - A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. Methods of use and methods of designing calixarene-based peptide mimetics are described. | 12-06-2012 |
20130012555 | Compounds, Compositions and Methods for the Treatment of Islet Amyloid Polypeptide (IAPP) Accumulation in Diabetes - Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of IAPP or amylin fibril diseases, and the manufacture of medicaments for such treatment. | 01-10-2013 |
20130012556 | Bioactive Agrichemical Compositions and Use Thereof - Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations. | 01-10-2013 |
20130023571 | N- ( 4-PERFLUOROALKYL-PHENYL) -4-TRIAZOLYL-BENZAMIDES AS INSECTICIDES - The present invention relates to novel triazole-substituted benzamide derivatives, to processes and intermediates for preparing them, to methods of using them to control insect, acarine, nematode and mollusc pests, and to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising them. Formula (I). | 01-24-2013 |
20130046002 | TRIAZOLE COMPOUND HAVING PESTICIDAL ACTIVITIES - To provide a triazole compound which has remarkably excellent pesticidal activities. Optically active (+)-1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole represented by the following formula (I), which is obtainable by subjecting a racemic modification of 1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]-5-amino-3-(trifluoromethyl)-1H-1,2,4-triazole to optical resolution: | 02-21-2013 |
20130109730 | TREATMENT OF LIVER DISEASES IN WHICH IRON PLAYS A ROLE IN PATHOGENESIS | 05-02-2013 |
20130137738 | FUNGICIDAL COMPOSITIONS FOR TURF TREATMENT AND IMPROVEMENT - The present invention relates to novel compositions comprising: a fungicide that inhibits mitochondrial respiration at the QoI site (QoI inhibitor), a contact fungicide, a demethylation inhibitor, and pigments, which are highly suitable for controlling unwanted phytopathogenic fungi. Moreover, the fungicidal compositions are able to control mold and fungus infection in grasses and in particular turf grasses. | 05-30-2013 |
20130165491 | THERAPEUTIC AGENT FOR PAIN | 06-27-2013 |
20130172395 | COMPOUNDS FOR ANTI-FUNGAL TREATMENT - Provided are methods of treating or preventing a fungal infection in a subject. The methods comprise selecting a subject with or at risk of developing a fungal infection and administering to the subject a therapeutically effective amount of toremifene and fluconazole or derivatives thereof. | 07-04-2013 |
20130203826 | Pure Intermediate - The present invention relates to an improved process for the preparation of Letrozole (I) and its synthetic intermediate 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III). In particular, it relates to a process to prepare Letrozole and its intermediate (III) substantially free from regioisomeric impurities. The present invention further relates to acid addition salts of 4-[(1-(1,2,4-triazoly)methyl]benzonitrile (III) such as the oxalate salt, and also to Letrozole (I), the intermediate (III) and salts thereof preparable by the processes of the present invention. | 08-08-2013 |
20130210874 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS - In one aspect, the invention relates to compounds having the formula: | 08-15-2013 |
20130231378 | INHIBITORS OF AkT ACTIVITY - Invented are novel heterocyclic carboxamide compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis. | 09-05-2013 |
20130245084 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS - Compounds of general formula (I) their use as calcium receptor-active compounds for the prophylaxis, treatment or amelioration of physiological disorders or diseases associated with disturbances of CaSR activity, such as hyperparathyroidism, pharmaceutical compositions comprising said compounds, and methods of treating diseases with said compounds. | 09-19-2013 |
20130267572 | Plymorphic Forms of Deferasirox (ICL670A) - The invention relates to crystalline forms of 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid and to its amorphous form, to processes for the preparation thereof, to compositions containing the same and their uses for the manufacture of a medicament for the treatment of the human body. | 10-10-2013 |
20130281502 | POST-TREATMENT BREAST CANCER PROGNOSIS - The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to extended treatment and cancer-free survival in a patient. In particular, the disclosure includes the identities of genes that are expressed in correlation with benefit in a switch in endocrine therapy used to treat a patient. The levels of gene expression are disclosed as a molecular index for predicting clinical outcome, and so prognosis, for the patient. The disclosure further includes methods for predicting cancer recurrence, and/or predicting occurrence of metastatic cancer, after initial treatment with an anti-estrogen agent. The disclosure further includes methods for determining or selecting the treatment of a subject based upon the likelihood of life expectancy, cancer recurrence, and/or cancer metastasis. | 10-24-2013 |
20130296387 | TOPICAL NON-AQUEOUS PHARMACEUTICAL FORMULATIONS - The present application relates to non-aqueous pharmaceutical formulations containing an anti-microbial agent. | 11-07-2013 |
20130296388 | PHENOL-CONTAINING AZOLE COMPOSITIONS FOR THE PROTECTION OF INDUSTRIAL MATERIALS - A process for the protection of industrial materials in which a composition, comprising at least one azole and at least one phenol, is employed so as to treat the industrial material. | 11-07-2013 |
20130303579 | HYBRID MOLECULES CONTAINING PHARMACOPHORES OF FLUCONAZOLE AS ANTIFUNGAL AGENTS AND THEIR PREPARATION - Disclosed herein are novel antifungal compounds of Formula 1, containing fluconazole pharmacophore moieties coupled with other moieties including aryl enones and chalcones and pharmaceutically acceptable salts thereof, methods for preparing these compounds and pharmaceutical preparations containing these novel compounds for prevention and treatment of fungal infections. | 11-14-2013 |
20130310433 | THIOPHENE-CARBOXAMIDES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising said compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, or disorders. The invention also relates to processes for preparing compounds of the inventions. | 11-21-2013 |
20140005240 | COMPOUNDS AND COMPOSITIONS FOR USE AS MODULATORS OF TAU AGGREGATION AND ALLEVIATION OF TAUOPATHIES | 01-02-2014 |
20140039018 | MYCOTOXIN ACCUMULATION INHIBITION METHOD AND MYCOTOXIN ACCUMULATION INHIBITOR - An fungicide capable of inhibiting the accumulation of the mycotoxin in a crop effectively and a mycotoxin accumulation inhibition method using said fungicide are provided. The mycotoxin accumulation inhibition method according to the invention is a mycotoxin accumulation inhibition method for inhibiting the accumulation of the mycotoxin in a grain after cropping comprising a first fungicide treatment step for treating the cereal plant after the flowering stage with a fungicide containing metconazole as an active ingredient. | 02-06-2014 |
20140051735 | USE OF N-PHENYLETHYLPYRAZOLE CARBOXAMIDE DERIVATIVES OR SALTS THEREOF FOR CONTROLLING POWDERY MILDEW PRIMARY INFECTIONS - The present invention relates to the use of N-phenylethylpyrazole carboxamide derivatives, in particular 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid [2-(2,4-dichlorophenyl)-2-methoxy-1-methyl-ethyl]-amide for controlling powdery mildew primary infections in crops and to a method for controlling those primary infections. | 02-20-2014 |
20140051736 | FUNGICIDAL COMPOSITIONS - The invention relates to fungicidal compositions comprising as active ingredient a combination of components A) and B) as defined in the patent claims, to a method of controlling phytopathogenic diseases on crop plants using such a composition and to a method of protecting natural substances of vegetable and/or animal origin and/or their processed forms using such a composition. | 02-20-2014 |
20140057956 | COPOLYMERISED FATTY BODY, PREPARATION METHOD THEREOF AND USES OF SAME - The invention relates to a copolymer having a backbone that is obtained by radical polymerisation of: a fatty body (A) comprising unsaturations and/or hydroxyl functions; and at least one monomer (B) including at least one function that can be polymerised by means of radical polymerisation and comprising either (i) at least one linear or branched alkyl chain having preferably between 16 and 44 carbon atoms, and more preferably at least 18 carbon atoms, e.g. at least 20 carbon atoms, in particular 22 carbon atoms or 44 carbon atoms, or (ii) a reactive function. The invention also relates to a method for modifying the rheological properties of an non-aqueous medium with the addition of a copolymer of the invention. The invention further relates to a composition formed totally or partially by a copolymer of the invention. Preferably, the composition is an emulsifiable composition. Furthermore, the invention relates to a composition comprising a copolymer of the invention and an emulsifying agent. | 02-27-2014 |
20140073678 | ANTI-PAIN AND ANTI-NAUSEA AND/OR VOMITING COMBINATORIAL COMPOSITIONS - In one aspect, the present invention discloses combinational compositions for treating users experiencing symptoms associated with a migraine or other central nervous system related pain disorder that can cause or exacerbate nausea and/or vomiting or other central nervous system related pain disorder that can cause or exacerbate nausea and/or vomiting. The combinational composition includes a first pharmaceutical active component for treating pain, and a second pharmaceutical active component for treating nausea and/or vomiting and/or vomiting in a user. | 03-13-2014 |
20140107171 | Methods of Treating an Overweight or Obese Subject - The invention herein generally relates to methods of treating a subject having an overweight or obese condition, and overweight- or obesity-related conditions. In one embodiment, the invention herein provides a method of treating a subject having an overweight or obese condition involving administering to the subject in need thereof, an amount of a pharmaceutical composition including a MetAP-2 inhibitory compound, or a salt, ester, or prodrug thereof, effective to result in weight loss in the subject. | 04-17-2014 |
20140206730 | COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES - The present invention provides a composition for controlling plant diseases having an excellent control efficacy on plant diseases. A composition for controlling plant diseases comprising an amide compound represented by a formula (I): wherein each of symbols are the same as defined in the Description; or salts thereof and one or more kinds of azole compounds selected from the group (A) consisting of tebuconazole, difenoconazole, triticonazole, imazalil, triadimenol, fluquinconazole, prochloraz, prothioconazole, diniconazole, diniconazole M, cyproconazole, tetraconazole, ipconazole, triforine, pyrifenox, fenarimol, nuarimol, oxpoconazole fumarate, pefurazoate, triflumizole, azaconazole, bitertanol, bromuconazole, epoxiconazole, fenbuconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, myclobutanil, penconazole, propiconazole, simeconazole, triadimefon and metconazole, shows an excellent controlling efficacy on plant diseases. | 07-24-2014 |
20140206731 | COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES - The present invention provides a composition for controlling plant diseases having an excellent control efficacy on plant diseases. A composition for controlling plant diseases comprising an amide compound represented by a formula (I); wherein each of symbols are the same as defined in the Description; or salts thereof and at least one kind of azole compounds selected from the group (A) consisting of tebuconazole, difenoconazole, triticonazole, imazalil, triadimenol, fluquinconazole, prochloraz, prothioconazole, diniconazole, diniconazole M, cyproconazole, tetraconazole, ipconazole, triforine, pyrifenox, fenarimol, nuarimol, oxpoconazole fumarate, pefurazoate, triflumizole, azaconazole, bitertanol, bromuconazole, epoxiconazole, fenbuconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, myclobutanil, penconazole, propiconazole, simeconazole, triadimefon and metconazole, shows an excellent controlling efficacy on plant diseases. | 07-24-2014 |
20140213622 | PHARMACEUTICAL COMPOSITIONS COMPRISING AN AROMATSE INHIBITORS - The invention relates to low-dose pharmaceutical compositions comprising the aromatase inhibitor 4,4′[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, as the active ingredient in a suitable carrier. The present invention also relates to a process for their preparation and to their use as therapeutic agents. | 07-31-2014 |
20140221440 | COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES - The present invention provides a composition for controlling plant diseases having an excellent control efficacy on plant diseases. A composition for controlling plant diseases comprising a carboxylic acid compound represented by a formula (I): wherein each of symbols are the same as defined in the Description; or salts thereof and one or more kinds of azole compounds selected from the group (A) consisting of tebuconazole, difenoconazole, triticonazole, imazalil, triadimenol, fluquinconazole, prochloraz, prothioconazole, diniconazole, diniconazole M, cyproconazole, tetraconazole, ipconazole, triforine, pyrifenox, fenarimol, nuarimol, oxpoconazole fumarate, pefurazoate, triflumizole, azaconazole, bitertanol, bromuconazole, epoxiconazole, fenbuconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, myclobutanil, penconazole, propiconazole, simeconazole, triadimefon and met conazole, shows an excellent controlling efficacy on plant diseases. | 08-07-2014 |
20140235684 | METAL-SALEN COMPLEX COMPOUND RESPONSIVE DRUG AND INTRA-CORPOREAL BEHAVIOR CONTROL SYSTEM FOR METAL-SALEN COMPLEX COMPOUND - A metal-salen complex compound responsive drug, which has an antidotal property capable of neutralizing cytotoxicity of a metal-salen complex compound, and an intra-corporeal behavior control system for the metal-salen complex compound are provided. This metal-salen complex compound responsive drug contains an effective amount of a metal chelating agent to suppress side effects by the metal-salen complex compound. | 08-21-2014 |
20140249193 | MODULATORS OF MITOCHONDRIAL PROTEIN IMPORT - The present invention provides compounds that modulate protein translocation in mitochondria, compositions thereof, and methods of identifying, making and using these. | 09-04-2014 |
20140249194 | OPTICALLY ACTIVE FLUCONAZOLE ANALOGUES CONTAINING THIOPHENES AS ANTIFUNGAL AGENTS - The invention discloses optically active compounds of Formula (1a) or Formula (1b), | 09-04-2014 |
20140275194 | FILMS AND DRUG DELIVERY SYSTEMS FOR RIZATRIPTAN - The invention relates to film products including a polymer component and a therapeutically effective amount of rizatriptan or a pharmaceutically acceptable salt thereof. The invention further relates to film products including a polymer component and a therapeutically effective amount of rizatriptan benzoate. | 09-18-2014 |
20140288136 | METHODS AND USES OF CYTOCHROME P450 INHIBITORS - Methods are provided for treating or preventing chronic obstructive pulmonary diseases such as emphysema, and fibrotic diseases including heart, liver, kidney and vascular diseases, by administering to a subject a pharmaceutical composition comprising a compound that inhibits cytochrome P450RA or CYP26. | 09-25-2014 |
20140309267 | USE OF AN AROMATASE INHIBITOR FOR THE TREATMENT OF HYPOGONADISM AND RELATED DISEASES - The aromatase inhibitor 4,4′-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile increases testosterone levels and treats hypogonadism and related diseases. A particular dosing regimen is disclosed as well as pharmaceutical compositions comprising said of 4,4′-[fluoro-(1-H-1,2,4-triazol-1-yl)methylene]bisbenzonitrile, optionally in combination with other active ingredients and kits comprising the pharmaceutical compositions. | 10-16-2014 |
20140315967 | AZOLE DERIVATIVE AND USES THEREOF - In order to provide a compound which exhibits a high controlling effect against plant diseases and is able to reduce phytotoxicity, the present invention is a triazole derivative represented by General Formula (I), the azole derivative being a (−)-enantiomer or (+)-enantiomer having an —R | 10-23-2014 |
20140336230 | METHOD OF INCREASING METABOLISM - The present invention provides a method for increasing metabolism and/or energy expenditure in a subject, e.g., to treat or prevent obesity and/or a related condition and/or the reduce adiposity, the method comprising increasing the level and/or activity of Hypoxia Induced Factor 1α (HIF-1α) in a cell, tissue or organ of the subject, thereby increasing metabolism in the subject. The present invention also provides a method for increasing metabolism in a subject, the method comprising administering an iron chelating agent to the subject, thereby increasing metabolism in the subject. | 11-13-2014 |
20150018402 | PESTICIDAL DISPERSIBLE CONCENTRATE FORMULATIONS - The present invention relates to non-aqueous pesticidal dispersible concentrate formulations comprising from about 2 to about 10% of at least one pesticidal agent, from about 15 to about 25% of hexylene glycol, from about 65 to about 75% of propylene glycol, a hydrophobic silica, and a surfactant, wherein the weight percentages are based on the total weight of the formulation. Formulations of the present invention have superior storage stability but are non-phytotoxic to seeds when used as a seed treatment. The present invention also relates to ready-to-use products made from the concentrated formulations of the present invention. Further, the present invention includes methods of using the pesticidal dispersible concentrate formulations and ready-to-use products to achieve superior plant protection and disease control. | 01-15-2015 |
20150038540 | INSTANTLY WETTABLE ORAL FILM DOSAGE FORM WITHOUT SURFACTANT OR POLYALCOHOL - An instantly wettable and rapidly disintegrating oral film dosage form without a surfactant and without a polyalcohol was achieved by combining at least one water soluble polymer that is not a copolymer of vinylpyrrolidone, at least one active agent, a copolymer of vinylpyrrolidone and titanium dioxide. In certain embodiments, the film comprises hydroxypropyl cellulose or a combination of hydroxypropyl cellulose and a polymer or copolymer of vinylpyrrolidone or a substituted vinylpyrrolidone as the water soluble polymer(s). A plasticizer, and optional additives selected from synthetic sweeteners, natural sweeteners, flavorants, antioxidants, colorants, and opacifiers, can be added to the disclosed film oral dosage forms. | 02-05-2015 |
20150065545 | Transdermal Delivery of Anastrozole for Systemic Effect - Formulations and methods for transdermal drug delivery compositions that include anastrozole are disclosed. Transdermal anastrozole compositions of the present disclosure may be indicated for treating testosterone deficiency. Disclosed transdermal anastrozole compositions may include permeation enhancers that may improve penetration of anastrozole in human skin. Permeation enhancers within transdermal anastrozole compositions may include oils from Amazon rainforest such as Pracaxi oil, | 03-05-2015 |
20150094347 | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE - Benzoxepin compounds of Formula I, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, wherein: Z | 04-02-2015 |
20150105437 | Process for the Preparation of Random Radical Copolymers, and Active Substance Compositions Obtainable Therefrom - A process for the preparation of random radical copolymers which comprises
| 04-16-2015 |
20150126569 | QUATERNARY FUNGICIDAL MIXTURE - A quaternary fungicide mixture for controlling diseases of turfgrass and/or ornamentals. | 05-07-2015 |
20150366190 | Sustained Release Methods to Defeat Plant Pests - A dilute concentrate for treating vegetation for suppressing fungi thereon, formed from a concentrate having components added in the following sequence fungicide, EtOH, and surfactant, at about 1:3:1 weight percent, respectively, and forming supramolecular assemblies comprising surfactant/fungicide/EtOH, surfactant/fungicide, and free non-associated fungicide; and a latex/water solution, wherein the supramolecular assemblies in the dilute concentrate now include latex/fungicide/surfactant, latex/fungicide, and free fungicide. Upon drying of a latex film from the dilute concentrate supramolecular assemblies, the composition of the assemblies regulates the release of fungicide from the dried latex film by the formation of active pools with varying water solubility, wherein the surfactant forms supramolecule assemblies with the fungicide via a non-covalent mechanism to produce (i) a composite surfactant/fungicide combination, a fraction of which assembles with the polymerizing latex via a non-covalent mechanism to form additional supramolecular assemblies and (ii) a fungicide/latex combination that is formed by a non-covalent mechanism. | 12-24-2015 |
20160002189 | PROCESS FOR THE PREPARATION OF SUBSTITUTED OXIRANES AND TRIAZOLES - The present invention relates to a process for the preparation of the compounds II | 01-07-2016 |
20160008326 | BICYCLIC COMPOUND, PRODUCTION AND USE THEREOF | 01-14-2016 |
20160021877 | EMULSIFIABLE CONCENTRATE COMPRISING PESTICIDE, ALKYL BENZOATE AND FATTY ACID AMIDE - Subject matter of the present invention is an emulsifiable concentrate comprising a water-insoluble pesticide, an alkyl benzoate, and an amide of the formula (I) as defined herein. The invention further relates to a process for the preparation of said concentrate; an emulsion obtainable by mixing water, a water-insoluble pesticide, the alkyl benzoate, and the amide; and to a method for controlling phytopathogenic fungi and/or undesired vegetation and/or undesired attack by insects or mites and/or for regulating the growth of plants, where the concentrate or the emulsion is allowed to act on the respective pests, their environment or on the crop plants to be protected from the respective pests, on the soil and/or on undesired plants and/or on the crop plants and/or their environment. | 01-28-2016 |
20160102063 | METHOD OF INCREASING METABOLISM - The present invention provides a method for increasing metabolism and/or energy expenditure in a subject, e.g., to treat or prevent obesity and/or a related condition and/or to reduce adiposity, the method comprising increasing the level and/or activity of Hypoxia Induced Factor 1α (HIF-1α) in a cell, tissue or organ of the subject, thereby increasing metabolism in the subject. The present invention also provides a method for increasing metabolism in a subject, the method comprising administering an iron chelating agent to the subject, thereby increasing metabolism in the subject. | 04-14-2016 |
20160175255 | DEFERACIROX DISPERSIBLE TABLETS | 06-23-2016 |
20160185761 | Compounds for Enhancing the Cognitive Function - The invention relates to 2-oxo-1-pyrrolidinyl triazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals for enhancing the cognitive function or to counteract cognitive decline. | 06-30-2016 |
20160249619 | QUATERNARY FUNGICIDAL MIXTURE | 09-01-2016 |