Class / Patent application number | Description | Number of patent applications / Date published |
514398000 | Chalcogen or nitrogen bonded directly to the imidazole ring by nonionic bonding | 66 |
20080221189 | Use of Metronidazole For Preparing a Pharmaceutical Composition For Treating Pathologies Related to the B-Type Receptor of Interleukin 8 and/or to a Pacap Type 1 Receptor - The invention relates to use of metronidazole for the preparation of a pharmaceutical composition for treating pathologies involving at least one receptor chosen from the group comprising the IL-8RB receptor and the PAC-1 receptor. | 09-11-2008 |
20080234344 | Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use - The invention provides novel compounds of general formula I | 09-25-2008 |
20080287513 | Topical compositions containing metronidazole - Aqueous compositions containing solubilized metronidazole at a concentration of about 0.75% by weight or greater are able to be obtained by using the combination of solubility enhancing agents, one of which is niacinamide and the other is urea. Related methods are also disclosed. | 11-20-2008 |
20080287514 | Topical compositions containing metronidazole - Aqueous compositions containing solubilized metronidazole at a concentration of about 0.75% by weight or greater are able to be obtained by using the combination of solubility enhancing agents, one of which is niacinamide and the other is hydroxyalkyl urea. Related methods are also disclosed. | 11-20-2008 |
20080287515 | Topical compositions containing metronidazole - Aqueous compositions containing solubilized metronidazole at a concentration of about 0.75% by weight or greater are able to be obtained by using the combination of solubility enhancing agents, one of which is urea and the other is hydroxyalkyl urea. Related methods are also disclosed. | 11-20-2008 |
20080312304 | Topical compositions containing metronidazole - Aqueous compositions containing solubilized metronidazole at a concentration of about 0.75% by weight or greater are able to be obtained by using the combination of solubility enhancing agents, first one is niacinamide, second one is urea, and third one is hydroxyalkyl urea. Related methods are also disclosed. | 12-18-2008 |
20080312305 | Imidazoles as Gaba- B Receptor Modulators - The present invention relates to novel imidazole derivatives having a positive allosteric GABA | 12-18-2008 |
20090030060 | INTRAVAGINAL TREATMENT OF VAGINAL INFECTIONS WITH METRONIDAZOLE COMPOSITIONS - The present invention provides a buffered non-flowing composition suitable for the treatment of bacterial vaginosis. The composition includes metronidazole in a concentration of about 0.50% (w/w) to about 1.50% (w/w). The metronidazole is present together with a buffer system in a physiologically tolerable medium. The buffer system provides an acidic buffered pH value for the composition in the range of about 5.0 to about 6.0. The present invention also provides for a method for inhibiting a microorganism. The method includes contacting a microorganism with an effective amount of the composition of the present invention, for a period of time effective to inhibit the microorganism. The present invention also provides for a method for treating bacterial vaginosis in a human patient. The method includes intravaginal administration to a patient in need of such treatment an effective amount of the composition the present invention. The composition is introduced into the vagina at least once a day for a time period of at least one day. | 01-29-2009 |
20090137653 | SUBSTITUTED BENZYLAMINES AS CYP2A INHIBITORS AND USES THEREOF TO TREAT NICOTINE DEPENDENCE - This invention is directed to substituted benzylamines which are useful as inhibitors of the CYP2A6 enzyme. Pharmaceutical compositions comprising the compounds and methods of using the compounds to treat nicotine dependence are also disclosed. | 05-28-2009 |
20090163567 | GERMICIDE COMPOSITION FOR AGRICULTURAL AND GARDENING APPLICATIONS AND METHOD FOR CONTROLLING PLANT DISEASE - It is to provide a composition having stable and high fungicidal effects against cultivated crops infected with plant diseases. | 06-25-2009 |
20090163568 | AVERMECTIN/METRONIDAZOLE COMPOSITIONS FOR TREATING AFFLICTIONS OF THE SKIN, E.G., ROSACEA - Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and metronidazole or salt, ester or derivative thereof, are useful for treating afflictions of the skin, especially rosacea. | 06-25-2009 |
20090215849 | High stability aqueous gels comprising metronidazole and methods for the preparation thereof - A method for preparing highly stable aqueous gels based on metronidazole, well suited for treating such skin conditions as rosacea, acne and dermatitis, entails the successive steps of: | 08-27-2009 |
20090221659 | COMBINATION OF ALPHA-2 RECEPTOR AGONIST (CLONIDIN) AND ANTI-MUSCARINIC AGENT (OXYBUTYNIN) FOR THE TREATMENT OF SIALORRHOEA - An alpha2 adrenoreceptor agonist eg. clonidine, brimonidine, monoxidine, lofexidine is useful for the treatment of siaiorrhoea, administered by the paraungual, sublingual or buccal route. The patient to be treated is also given an anti-muscarinic agent eg. oxybutynin, glycopyrrolate, ipratropium. | 09-03-2009 |
20090253765 | Angiogenesis Inhibitor Containing Amine Derivative as Active Ingredient - An object of the present invention is to provide an angiogenesis inhibitor. The angiogenesis inhibitor according to the present invention contains a compound represented by the following general formula [I] or a salt thereof as an active ingredient. In the formula, the ring A represents a benzene ring or a naphthalene ring; X represents a single bond, an alkylene group or —CH | 10-08-2009 |
20090326030 | Use of Levo-Ornidazole in the Preparation of Anti-Anaerobic Bacteria Infection Drugs - The use of levo-ornidazole in the preparation of medicine for preventing and treating the anti-anaerobic bacteria infection is provided. It is demonstrated that levo-ornidazole exhibits lower toxicity and less central inhibition effects than dextro-ornidazole or racemic ornidazole. L-ornidazole possesses pharmacokinetics characteristics, which are superior to that of the racemic ornidazole, and anti-anaerobic activities which are slightly better than or substantially the same as that of the racemic ornidazole. Also, this invention particularly relates to a preparation process, which comprises formulating L-ornidazole as anti-anaerobic infection pharmaceutical preparations, which are suitable for clinical uses. | 12-31-2009 |
20100035952 | Radiosensitizer Formulations and Methods for Use - The present invention provides radiosensitizer compositions, in controlled-release formulations or other acceptable formulations, particularly nitrohistidine radiosensitizer compositions, which may be administered by any suitable means including oral, intravenous, arterial infusion, intraperitoneal, intramuscular, subcutaneous, surgical, and topical. Optionally, radiosensitizer compositions may be formulated with other agents, including chemotherapy agents and agents that provide a synergistic radiosensitizing effect. Methods of potentiating radiotherapy cancer treatment of cancers in humans, particularly of astrocytomas, are also presented, wherein a radiosensitizer composition is administered and radiotherapy is directed to the site of the tumor. Chemotherapy regimens may also be used as adjuvant therapy. | 02-11-2010 |
20100048659 | Aqueous compositions containing metronidazole - An aqueous solution of metronidazole in which the concentration of metronidazole is higher than 0.7%. The solution contains a combination of solubility-enhancing agents, one of which is niacinamide. Methods of manufacture and therapeutic use of the solution are disclosed. | 02-25-2010 |
20100076042 | PHARMACEUTICAL COMPOSITION - To provide a pharmaceutical composition which can enhance the storage stability of 1-(1-hydroxymethyl-2,3-dihydroxypropyloxymethyl)-2-nitroimidazole without impairing the effect of the compound. | 03-25-2010 |
20100081697 | CRYSTALLINE FORM OF AN ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID - The invention provides a crystalline freebase form of 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compound, processes and intermediates for preparing the crystalline compound, and methods of using the crystalline compound to treat diseases such as hypertension. | 04-01-2010 |
20100105750 | STABLE METRONIDAZOLE GEL FORMULATIONS - The invention provides aqueous gel compositions comprising metronidazole, benzyl alcohol as a solvent, water, and a polyacrylic acid or cellulosic gelling agent, wherein the benzyl alcohol is present in an amount effective to maintain the physical stability of the aqueous gel composition for at least seven days at 5° C. The invention also provides methods of using and methods of preparing the aqueous gel compositions. | 04-29-2010 |
20100130576 | PHARMACEUTICAL COMPOSITION - To provide a pharmaceutical composition containing a 2-nitroimidazole derivative, which has high solubility in an aqueous carrier and high stability. | 05-27-2010 |
20100144814 | NOVEL 4-PHENYLIMIDAZOLE-2-THIONE TYROSINASE INHIBITORS AND PHARMACEUTICAL/COSMETIC APPLICATIONS THEREOF - Novel 4-phenylimidazole-2-thione tyrosinase inhibiting compounds corresponding to the following general formula (I): | 06-10-2010 |
20100152264 | 3- TO 7-MEMBERED 1,3-DIAZA-4-OXO-HETEROCYCLIC DERIVATIVES CAPABLE OF RELEASING ACTIVE ALDEHYDES OR KETONES - The present invention provides 3- to 7-membered 1,3-diaza-4-oxo-heterocyclic derivatives, such as imidazolidinone O derivatives, capable of releasing in a controlled manner a biologically active aldehyde or ketone in the surrounding. The invention also relates to the use of these compounds as perfuming or flavoring ingredients, as well as to the perfuming compositions and consumer articles containing such derivatives. It also provides a process for preparing said derivatives of the invention | 06-17-2010 |
20100305178 | Pharmaceutical Composition - A topical composition comprises at least 5-wt % metronidazole or a pharmacologically acceptable derivative thereof in a non-aqueous vehicle. The composition may be used in the treatment of conditions of the colon, rectum, anorectum and perianal region, in particular inflammatory bowel disease and perianal Crohn's disease. The composition also relieves pain and inflammation and promotes healing of the colon, rectum, and anorectum and perianal region following surgical operations. One advantage of the composition is that topical administration of metronidazole results in a primarily local effect and thus side effects observed from systemic administration are avoided. | 12-02-2010 |
20100317707 | Oligomer-Nitroimidazole Anti-Infective Conjugates - The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. | 12-16-2010 |
20110028528 | PESTICIDAL AQUEOUS SUSPENSION COMPOSITION - When an organosilicone surface active agent is added to a pesticidal aqueous suspension composition containing an active ingredient compound of a sparingly water-soluble pesticide for the purpose of attaining activity enhancement and formulation, the following problems arise: such that (1) the viscosity of the composition increases; (2) a large amount of foams due to the organosilicone surface active agent tends to generate at the time of preparation of a spray solution; and the like. Thus, measuring the composition and preparation of a spray solution were difficult. The present invention provides a pesticidal aqueous suspension composition including (a) an active ingredient compound of a sparingly water-soluble pesticide, (b) an organosilicone surface active agent, (c) a viscosity-reducing agent, (d) an antifoaming agent, (e) a pH adjustor and (f) a dispersant, which is suppressed in increasing in the viscosity, is easy to measure, hardly generates foams at the time of dilution with water and is easy to prepare a spray solution. | 02-03-2011 |
20110092557 | Neuraminidase Inhibitors And Compositions And Methods Related Thereto - The present invention provides compounds comprising amino acid R groups, compositions comprising the same, and methods of inhibiting neuraminidase and/or treating influenza, | 04-21-2011 |
20110160265 | METHOD OF TREATING MOTOR DISORDERS WITH ALPHA-2B ADRENERGIC RECEPTOR AGONISTS - Disclosed herein is a method of treating motor disorders comprising administering to a subject in need of such treatment an alpha-2 receptor agonist lacking significant alpha-2A receptor activity. | 06-30-2011 |
20110218224 | CRYSTALLINE ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID AND METHODS FOR PREPARING THEREOF - The invention provides a micronized 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid having improved stability. The invention also provides pharmaceutical compositions comprising the stable micronized compound, processes for preparing the stable micronized compound, and methods of using the stable micronized compound to treat diseases such as hypertension. | 09-08-2011 |
20110224272 | CRYSTALLINE FORM OF AN ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID - The invention provides a crystalline freebase form of 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compound, processes and intermediates for preparing the crystalline compound, and methods of using the crystalline compound to treat diseases such as hypertension. | 09-15-2011 |
20110237637 | METRONIDAZOLE-BASED DERMATOLOGICAL FOAM AND EMULSIONS FOR THE PRODUCTION THEREOF - Oil-in-water emulsions expandable into stable foams having diminished inhibitor of skin breathing and useful for the treatment of dermatological conditions/afflictions, e.g., rosacea, advantageously contain:
| 09-29-2011 |
20110237638 | METRONIDAZOLE-BASED DERMATOLOGICAL FOAM AND EMULSIONS FOR THE PREPARATION THEREOF - Oil-in-water emulsions expandable into stable foams having diminished inhibitor of skin breathing and useful for the treatment of dermatological conditions/afflictions, e.g., rosacea, advantageously contain:
| 09-29-2011 |
20120108644 | AGRICULTURAL OR HORTICULTURAL FUNGICIDE COMPOSITION AND ITS USE FOR CONTROLLING PLANT PATHOGENS - The present invention provides a composition in which a fungicidal effect against a cultivated crop infected by a plant pathogen is stable and highly active. An excellent agricultural or horticultural fungicide composition for controlling a plant pathogen is provided by using (a) at least one imidazole compound represented by formula (I): | 05-03-2012 |
20120115920 | CRYSTALLINE FORMS OF AN ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID - The invention provides crystalline salt forms of 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]-imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compounds, processes and intermediates for preparing the crystalline compounds, and methods of using the crystalline compounds to treat diseases such as hypertension. | 05-10-2012 |
20120129905 | PHARMACEUTICAL COMPOSITION - To provide a pharmaceutical composition which can enhance the storage stability of 1-( | 05-24-2012 |
20120157506 | Novel Imidazole-2-Benzamide Compounds Useful for the Treatment of Osteoarthritis - The present invention provides compounds of the formula below | 06-21-2012 |
20120165381 | DUAL-ACTING IMIDAZOLE ANTIHYPERTENSIVE AGENTS - The invention is directed to compounds having the formula: | 06-28-2012 |
20120245211 | Methods of Treating Cognitive Dysfunction by Modulating Brain Energy Metabolism - Methods for treating cognitive dysfunction by modulating brain energy metabolism are discussed. | 09-27-2012 |
20120264796 | METHODS FOR MODULATING CIRCADIAN RHYTHMS - This disclosure described the role of AMPK in circadian rhythms and methods of screening for agents that modulate such rhythms, compositions that are useful for modulating such rhythms and uses thereof. | 10-18-2012 |
20120309805 | CRYSTALLINE FORM OF AN ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID - The invention provides a crystalline freebase form of 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compound, processes and intermediates for preparing the crystalline compound, and methods of using the crystalline compound to treat diseases such as hypertension. | 12-06-2012 |
20120316211 | Diagnostic Methods for Assessing Risk of Chagas Disease and Heart Failure - Provided herein are methods of detecting evidence of Chagas disease in a biological sample, comprising the step of measuring the presence of at least one protein selected from the group consisting of gelsolin, myosin light chain 2, vimentin, myosin heavy chain 11, vinculin, and plasminogen in said sample, wherein significantly elevated levels of the protein is a biomarker for the presence or severity of Chagas disease. | 12-13-2012 |
20130005787 | HIGH DOSAGE MUCOADHESIVE METRONIDAZOLE AQUEOUS-BASED GEL FORMULATIONS AND THEIR USE TO TREAT BACTERIAL VAGINOSIS - The present disclosure provides mucoadhesive aqueous-based gel formulations of metronidazole useful for a variety of purposes, including intravaginal application as a therapeutic approach towards the treatment of individuals suffering from and/or diagnosed with bacterial vaginosis. | 01-03-2013 |
20130158090 | METRONIDAZOLE ESTERS FOR TREATING ROSACEA - A compound of formula (I): | 06-20-2013 |
20130197048 | METRONIDAZOLE ESTERS FOR TREATING ROSACEA - A compound of formula (I): | 08-01-2013 |
20130217740 | METRONIDAZOLE ESTERS FOR TREATING ROSACEA - A compound of formula (I): | 08-22-2013 |
20130217741 | TOPICAL PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF SKIN DAMAGE - A topical composition comprising about 5 wt % to about 12.5 wt % of metronidazole or a pharmacologically acceptable salt thereof in a non-aqueous vehicle. The composition may be used in the treatment of skin damage due to inflammatory skin conditions; thermal, chemical or electrical burns; infections or radiation treatment. One advantage of the composition is that topical administration of metronidazole results in a primarily local effect, and thus, side effects observed from systemic administration are avoided. | 08-22-2013 |
20130217742 | Methods and Compositions for Increasing Solubility of Azole Drug Compounds that are Poorly Soluble in Water - The combination of any two of a polyol, a polyol ether, and a low carbon organic alcohol provides a synergistic effect on the solubility of azole compounds, such as metronidazole, in aqueous fluid. | 08-22-2013 |
20130267573 | CRYSTALLINE FORMS OF AN ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID - The invention provides crystalline salt forms of 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]-imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compounds, processes and intermediates for preparing the crystalline compounds, and methods of using the crystalline compounds to treat diseases such as hypertension. | 10-10-2013 |
20130274305 | CANCER TARGETING USING CARBONIC ANHYDRASE ISOFORM IX INHIBITORS - The present invention concerns novel carbonic anhydrase IX inhibitors comprising a nitroimidazole moiety and their use in therapy of hypoxic conditions, in particular cancer treatment, especially chemotherapy and radiotherapy. The compounds of the invention have an increased specificity for the carbonic anhydrase IX enzyme compared to the art. The present invention relates to novel nitroimidazole derivates represented by formula (1). | 10-17-2013 |
20130296393 | METHOD FOR CONTROLLING CLUBROOT - In order to control the clubroot of brassica vegetables which is settled-planted in a farm field, it is necessary to previously treat the seedling with a chemical before settled planting or treat the soil with a chemical, but the clubroot is sometimes not controlled depending on the weather or soil conditions. In addition, the treatment with a fungicidal compound at a high concentration causes a problem of phytotoxicity or crop persistence. An object of the present invention is to solve these problems and provide a method for easily and simply controlling clubroot without causing a problem of phytotoxicity or crop persistence. The present invention provides a method for controlling clubroot, comprising applying cyazofamid to brassica vegetables after seeding or settled planting in a farm field. | 11-07-2013 |
20140206735 | HIGH DOSAGE TOPICAL METRONIDAZOLE AQUEOUS-BASED GEL FORMULATIONS AND THEIR USE TO TREAT ROSACEA - The present disclosure provides aqueous-based gel formulations of metronidazole useful for a variety of purposes, including topical application as a therapeutic approach towards the treatment of individuals suffering from and/or diagnosed with rosacea. | 07-24-2014 |
20140213624 | METHOD FOR TREATING AND CURING LEISHMANIOSIS USING FEXINIDAZOLE - The present invention encompasses methods of using fexinidazole to treat and eliminate and/or cure | 07-31-2014 |
20140296314 | Methods for Treating Conditions Such as Dystonia and Post-Stroke Spasticity with Clonidine - Effective treatments of dystonia and/or post-stroke spasticity for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site, one can relieve dystonia and/or post-stroke spasticity caused by diverse sources. When appropriate formulations are provided within biodegradable polymers, this relief can be continued for at least five days. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days, at least one hundred and thirty-five days or at least one hundred and eighty days. | 10-02-2014 |
20140303222 | DUAL-ACTING IMIDAZOLE ANTIHYPERTENSIVE AGENTS - The invention is directed to compounds having the formula: | 10-09-2014 |
20140364474 | Imidazole Derivatives Useful for Controlling Microbial Growth - Disclosure is provided for 1,4,5-substituted amino imidazole compounds useful to control microbial growth, compositions including these compounds, devices including these compounds, and methods of using the same. | 12-11-2014 |
20140378520 | OLIGOMER-NITROIMIDAZOLE ANTI-INFECTIVE CONJUGATES - The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. | 12-25-2014 |
20150133518 | CRYSTALLINE FORMS OF AN ALKOXYIMIDAZOL-1-YLMETHYL BIPHENYL CARBOXYLIC ACID - The invention provides crystalline salt forms of 4′-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]-imidazol-1-ylmethyl}-3′-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compounds, processes and intermediates for preparing the crystalline compounds, and methods of using the crystalline compounds to treat diseases such as hypertension. | 05-14-2015 |
20150141476 | Use Of 2,5-Dihydroxybenzene Compounds And Derivatives For The Treatment Of Rosacea - The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea. | 05-21-2015 |
20150148393 | COSMETIC AND/OR PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF SKIN INFLAMMATION AND RELATED SYNDROMES - The invention relates to a cosmetic and/or pharmaceutical composition in combination with suitable carriers for topical use, comprising a mixture consisting of methyl sulfonyl methane and at least one compound belonging to the class of 4-alkyl cyclohexanols, which is useful in the treatment of various inflammatory conditions such as rosacea. The composition can act to simultaneously hinder both the release of chemical mediators which are up-regulated in rosacea and their action of causing the activation of TRPV receptors. The composition can reduce the effect of ultraviolet radiations on a skin already affected by an inflammatory process, and particularly, it can reduce the erythema induced by ultraviolet radiations on a skin already affected by an inflammatory process. | 05-28-2015 |
20150291536 | METHOD FOR PREPARING PHENYLOXYMETHYL-NITRO-IMIDAZOLE DERIVATIVES AND USE OF SAME - Fexinidazole is prepared according to a method which comprises the following steps: a) reacting 1-methyl-2-hydroxymethyl-5-nitro-imidazole with methanesulfonyl chloride in the presence of a suspension of powdered alkaline carbonate in an anhydrous organic solvent suitable for performing nucleophile substitution reactions; b) adding to the resulting reaction medium a solution of 4-methyl-mercapto-phenol in the same organic solvent as referred to in step a); c) separating fexinidazole from the reaction mixture as its hydrochloride salt and d) converting said hydrochloride salt into fexinidazole and optionally, purifying the latter. | 10-15-2015 |
20150306073 | THIOREDOXIN PROTEIN INHIBITORS AND USES THEREOF - A method of treating a fungal infection in a subject including administering to the subject a therapeutically effective amount of a thioredoxin protein inhibitor to treat the fungal infection in the subject. | 10-29-2015 |
20150366821 | ADRENERGIC AGONISTS FOR USE IN TREATING LIVER DAMAGE - The invention relates to liver damage, and to pharmaceutical compositions for use in treating, preventing or ameliorating liver damage or disease, especially acute liver damage. The invention is particularly, although not exclusively, concerned with treating or preventing liver damage caused by paracetamol poisoning. The invention also extends to methods of treating such conditions. | 12-24-2015 |
20160007593 | Fungicidal Composition | 01-14-2016 |
20160106714 | AQUEOUS-BASED METRONIDAZOLE GEL FORMULATIONS - The present disclosure provides mucoadhesive aqueous-based gel formulations of metronidazole useful for a variety of purposes, including intravaginal application as a therapeutic approach towards the treatment of individuals suffering from and/or diagnosed with bacterial vaginosis. | 04-21-2016 |
20160158199 | METHOD OF ACTIVATING REGULATORY T CELLS WITH ALPHA-2B ADRENERGIC RECEPTOR AGONISTS - Disclosed herein is a method of upregulating regulatory T-cells, and treating diseases that would benefit from such upregulation, by administering an alpha-2 receptor agonist. | 06-09-2016 |
20160194287 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | 07-07-2016 |