Entries |
Document | Title | Date |
20090005437 | Alpha-Ketoglutarates and Their Use as Therapeutic Agents - The present invention relates generally to the field of pharmaceuticals and medicine. More particularly, the present invention relates to certain compounds (e.g., α-ketoglutarate compounds; compounds that activate HIFα hydroxylase; compounds that increases the level of α-ketoglutarate, etc.) and their use in medicine, for example, in the treatment of cancer (e.g., cancer in which the activity of one of the enzymes in the tricarboxylic acid (TCA) cycle is down regulated), in the treatment of angiogenesis (e.g., hypoxia-induced angiogenesis). One preferred class of compounds are α-ketoglutarate compounds having a hydrophobic moiety that is, or is part of, an ester group formed from one of the acid groups of α-ketogluartic acid; and pharmaceutically acceptable salts, solvates, amides, esters, ethers, N-oxides, chemically protected forms, and prodrugs thereof. | 01-01-2009 |
20090005438 | Use of Isothiocyanates Compounds in Treating Prostatic Diseases and Skin Cancer - A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof. | 01-01-2009 |
20090005439 | STABLE ORGANIC PEROXIDE COMPOSITIONS - Methods of treating acne include the use of formulations including a benzoyl peroxide solution and an antioxidant. | 01-01-2009 |
20090018186 | STABLE BEVERAGE PRODUCTS COMPRISING POLYUNSATURATED FATTY ACID EMULSIONS - A beverage product comprising at least one beverage base and at least one polyunsaturated fatty acid emulsion, said emulsion comprising a continuous liquid phase; an emulsifier; and a discontinuous liquid phase comprising a blend including a polyunsaturated fatty acid source and a dispersing agent, the polyunsaturated fatty acid source comprising at least one polyunsaturated fatty acid, wherein the weight ratio of the fatty acid source to the dispersing agent in the blend ranges from about 9:1 to about 1:10. | 01-15-2009 |
20090036520 | Combinations of vasoprotective agents and formulations containing them - Combinations of vasoprotective agents useful for the prevention and the treatment of vascular injuries induced by an excess of plasma lipids comprising polycosanols, tocotriends and/or lycopene, procyanidole oligomers and vegetable oil rich in insaturated fatty acids. | 02-05-2009 |
20090048334 | Sodium ascorbate solubilisate - The invention relates to a solubilisate consisting of an aqueous solution of the alkali salts and/or alkaline-earth salts of ascorbic acid for foodstuffs, cosmetics and or similar and consisting of an emulsifier with an HLB value of between 9 and 18, for example a polysorbate, which also comprises one or more mid-chain triglycerides and/or one or more tocopherols. | 02-19-2009 |
20090088467 | VITAMIN E SUPPLEMENTATION TO TETANUS TOXOID - The invention relates to a formulation for supplementation on immune response to a biological substance. More particularly, the formulation consists of one or more forms of Vitamin E which provides a supplementation on immune response to tetanus toxoid. In addition, the present invention also relates on the effect of different types of Vitamin E such as tocotrienol rich fraction, delta tocotrienol and alpha-tocopherol supplementation on immune response to tetanus toxoid vaccination. | 04-02-2009 |
20090105330 | ADMIXTURE OF CAROTENOIDS AND ISOFLAVONOIDS FOR TREATING CUTANEOUS SYMPTOMS OF AGING - Intimate admixtures of at least one carotenoid and at least one isoflavonoid are well suited for treating the undesirable cutaneous signs of skin aging, in particular the determination of the skin and/or of the mucous membranes by inhibiting the activity and/or the expression of collagenases and by increasing the synthesis of collagen. | 04-23-2009 |
20090105331 | COMPOSITIONS OF ACTIVE INGREDIENTS - The present invention relates to compositions containing fat-soluble active ingredients and/or colorants in a matrix based on improved modified polysaccharides, i.e. modified polysaccharides where parts were separated, and to a process for preparing these compositions as well as to these improved modified polysaccharides themselves and a process for the manufacture thereof. The present invention further relates to the use of the compositions of this invention for the enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves. | 04-23-2009 |
20090131514 | BUCCAL, POLAR AND NON-POLAR SPRAYS CONTAINING PROPOFOL - Buccal aerosol sprays using polar and/or non-polar solvents have now been developed which provide propofol for rapid absorption through the oral mucosa, resulting in fast onset of effect. The buccal polar compositions of the invention comprise formulation I: propofol, a polar solvent and an optional flavoring agent; formulation II: propofol, a polar solvent, a propellant, and an optionally flavoring agent; formulation III: propofol, a non-polar solvent, and an optional flavoring agent; formulation IV: propofol, a non-polar solvent, a propellant, and an optional flavoring agent; formulation V: propofol, a mixture of a polar solvent and a non-polar solvent, and an optional flavoring agent; and formulation VI: propofol, a mixture of a polar solvent and a non-polar solvent, a propellant, and an optional flavoring agent. | 05-21-2009 |
20090137663 | Therapeutic micro nutrient composition for drug delivery - A lecithin based biphasic injection dosage formulation is disclosed which is applicable to subcutaneous, intramuscular, and intravenous administration. The formulation is characterized in that it comprises an adjustable buffer, an antoxidant, and a stabilizer. It is further characterized in that it includes liposomes, and that the components of these liposomes are therapeutic in the treatment of several human ailments. The formulation is characterized in that it comprises a carrier of biologically active substances. | 05-28-2009 |
20090156663 | Functional Foods Comprising Flavonoids and Tocotrienols and Methods Thereof - Disclosed in certain embodiments is a functional food comprising an active agent combination comprising flavonoids and tocotrienols. | 06-18-2009 |
20090156664 | Natural Vitamin E Compositions with Superior Antioxidant Potency - Compositions for increased antioxidant potency of natural vitamin E (d-alpha-tocopherol), comprising alpha-, beta-, delta-, and gamma-forms of tocopherols and tocotrienols are disclosed. All of these compositions provide 400 International Units (IU), based on one mg of d-alpha-tocopherol provides 1.49 IU. These compositions showed antioxidant activities superior to natural d-alpha-tocopherol. These compositions are designed to provide protection of the cell membrane lipid layer, and protection against heart disease, cancer, and eye disease. | 06-18-2009 |
20090156665 | Compositions Comprising Flavonoids and Toctrienols and Methods Thereof - Disclosed in certain embodiments is a pharmaceutical formulation comprising a pharmaceutical ingredient comprising an active agent combination comprising flavonoids and tocotrienols in a ratio of about 75:25 to about 95:5 and at least one pharmaceutically acceptable excipient. | 06-18-2009 |
20090163581 | Pharmaceutical Products for Treating Neoplastic Disease and Inflammation - Disclosed in certain embodiments is a pharmaceutical formulation and a functional food comprising a pharmaceutical ingredient comprising an active agent combination comprising flavonoids and tocotrienols in a ratio of about 75:25 to about 95:5 and at least one pharmaceutically acceptable excipient and methods to treat neoplastic diseases and inflammation. | 06-25-2009 |
20090176872 | Carotenoid Composition and Method for Protecting Skin - A method for protecting skin against damages caused by ultra-violet (uv) radiation from the sun, comprising administering to a subject in need of protection an effective amount of a composition containing lycopene from a natural source and one or more carotenoid selected from among phytoene and phytofluene or mixtures thereof. | 07-09-2009 |
20090203772 | Vaginal Health Products - The invention provides compositions and methods for increasing cell growth, stimulating cell turnover and promoting the secretion of mucus within the reproductive tract of a female mammal. | 08-13-2009 |
20090215885 | Antioxidant Food Composition and Methods and Uses Thereof - Various food compositions are provided that provide nutritional components useful, only or in combination with a training regime, to prevent or delay the onset of cognitive decline. | 08-27-2009 |
20090264520 | LIPID-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF - Lipid compositions comprising nuts, seeds, oils, legumes, fruits, grains, and dairy useful in specified amounts as dietary supplements and diet plans designed around and including the aforementioned for the prophylaxis and treatment of numerous diseases are disclosed. The compositions include omega-6 and omega-3 fatty acids where the ratio of the omega-6 to the omega-3 fatty acids and their amounts are controlled based on one or more factors including age of the subject, sex of the subject, diet of the subject, the body weight of the subject, medical conditions of the subject, and climate of the subject's living area. | 10-22-2009 |
20090306198 | Anti-Oxidant Synergy Formulation Nanoemulsions to Treat Caner - A uniform microfluidized nanoemulsion is disclosed containing a synergistic combination of two antioxidants and a cell membrane stabilizer phospholipid (i.e., an anti-oxidant synergy formulation; ASF). The microfluidized nanoemulsion improves the combination's cell membrane permeability by at least four-fold over conventional nanoemulsion compositions, which significantly increases the intracellular concentration of typically cell-impermeant antioxidants (i.e., for example, tocopherol) and/or systemic bioavailability. As a nanoemulsion, synergistic combination has greater anticancer efficacy than the same combination applied as a free solution. | 12-10-2009 |
20100022636 | Compositions and Methods For Enhancing The Antioxidant Status of Animals - Compositions suitable for enhancing the antioxidant status of animals containing methionine, taurine, vitamin C, and vitamin E and methods for preparing and using such compositions to enhance the antioxidant status of animals. | 01-28-2010 |
20100063140 | WATER-SOLUBLE COMPOSITIONS OF BIOACTIVE LIPOPHILIC COMPOUNDS - Water-soluble compositions comprising a lipophilic compound and a solubilizing agent of the general formula: | 03-11-2010 |
20100069482 | GEL USEFUL FOR THE DELIVERY OF OPHTHALMIC DRUGS - It is described a gel composed of a mixture of a polymer which forms a gel, a buffer; a saccharide and one or more active ingredients useful for treating diseases of the eyes. | 03-18-2010 |
20100076072 | COMPOSITIONS AND METHODS OF VITAMIN E ADMINISTRATION - The present invention relates to compositions and methods of vitamin E administration. In particular, the present invention provides opposing effects, relative to inflammation, from the administration of two major forms of vitamin E (α-tocopherol and γ-tocopherol). | 03-25-2010 |
20100087520 | STABLE SOLUTIONS OF ORLISTAT FOR PHARMACEUTICAL DOSAGE FORMS - Liquid orlistat-containing fill materials suitable for encapsulating in hard or soft capsules are described herein. The fill material contains orlistat dissolved in one or more medium chain triglycerides or medium chain partial triglycerides, one or more citrate esters, and combinations thereof. The fill material can also contain one or more pharmaceutically acceptable excipients. In one embodiment, the fill material is substantially free of surfactants. The fill material can be encapsulated in hard or soft, gelatin or non-gelatin capsules. The capsules may be coated to modify release of orlistat from the capsule. Alternatively, the fill material can be encapsulated in an enteric capsule, wherein the enteric polymer is a component of the capsule shell, rather than a coating over the capsule shell. The fill materials are stable at elevated temperatures over an extended period of time and allow for high loadings of orlistat (e.g., 20% w/w or higher). | 04-08-2010 |
20100093845 | COMPOSITION AND METHOD FOR TREATING DRY EYE SYNDROME - The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of α-tocopheryl acetate; α-tocopheryl acetate and about 0.5% aqueous component; or α-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient. | 04-15-2010 |
20100113587 | Abscissic acid and derivatives thereof for the treatment of diseases - The present invention relates generally to the fields of molecular biology and pharmacology. More particularly, it concerns the use of abscissic acid to treat various diseases, including neurodegenerative diseases and neuromuscular diseases. | 05-06-2010 |
20100113588 | Composition and Methods for the Protection of Hair From Treated Pool Water - Compositions for treating hair are disclosed. Methods of making and using compositions for treating hair are also disclosed. | 05-06-2010 |
20100137427 | Softgel of NLKJ for treating prostate diseases - A softgel of NLKJ for the treatment of prostate diseases, comprising 0.05˜1.0 g of NLKJ and 0.05˜1.5 mg of an antioxidant, said NLKJ having the following physicochemical parameter: acid value<0.56, iodine value 95.0-107.00, saponification value 185.00-195.00, specific gravity 0.914-0.918 (20° C.), and refractive index 1.470-1.475 (20° C.). The inhibition of the softgel of NLKJ on the growth of prostate cancer in combination with the injection of Lupron is stronger than that of each of them used alone. | 06-03-2010 |
20100144861 | Perfluorocarbon gel formulations - A perfluorocarbon gel composition is disclosed with numerous uses including topical medical and cosmetic uses. | 06-10-2010 |
20100197780 | COMPOUNDS EXTRACTED FROM PALM OIL MILL EFFLUENT FOR THE TREATMENT OF CANCER, COMPOSITIONS THEREOF AND METHODS THEREWITH - The present invention describes a composition and methods for prevention and treatment of cancer comprising compounds extracted from Palm oil mill effluent. Also, the invention describes effective therapeutic dosages of the compounds and their combinations. The present invention can be prepared independently or as a combination product. | 08-05-2010 |
20100267820 | ANTIADHESION AGENTS - Vitamin E succinate derivatives according to formula I: | 10-21-2010 |
20100273871 | ANTICANCER TOCOPHERYL SUCCINATE DERIVATIVES - Compounds of formula I: | 10-28-2010 |
20100286257 | Methods Of Use Of Nitroalkane Compositions In Dermatologic Applications To Prevent or Treat Skin Aging - Topical compositions comprising an effective amount of a nitroalkene and a carrier are used to prevent or treat skin aging. | 11-11-2010 |
20100286258 | Process - A process for producing a composition comprising at least 3% by weight of total tocopherols and tocotrienols comprises:
| 11-11-2010 |
20100292316 | IMPROVED THERAPEUTIC METHODS AND COMPOSITIONS COMPRISING CHROMAN RING COMPOUNDS - The instant invention concerns chroman ring derivative compounds such as vitamin E derivatives and methods for their use. In certain aspects, methods for treating subjects comprising Arg, JNK, p73, NOXA or FOXO1 positive cancers are provided. In still further aspects, methods for treating cell proliferative disease such as cancer by administration of a chroman ring compound in conjunction with a P13 or Akt kinase inhibitor are described. | 11-18-2010 |
20100298425 | Use of Tocotrienols for Elevating IKBKAP Gene Expression and Treating Familial Dysautonomia - The present invention provides methods for elevating IKBKAP gene expression and the level of functional IKAP protein in cells, which are beneficial to human individual, such as an individual suffering from Familial Dysautonomia, by providing one or more tocotrienols alone or in combination with one or more tocopherols to the cells. The present invention also provides methods for treating Familial Dysautonomia by providing tocotrienols alone or in combination with one or more tocopherols to a patient having Familial Dysautonomia. Related therapeutic kits are also provided. | 11-25-2010 |
20100324132 | METHODS AND COMPOSITIONS FOR PROMOTING WOUND HEALING - The present invention provides methods and compositions that use the combination of Tris and EDTA to inhibit the growth of microorganisms at the site of a wound or burn, and/or to promote the healing of a wound or burn, and/or to reduce the sensation of pain at the site of a wound or burn. The amount of Tris and EDTA applied to a wound or burn can be selected to achieve one or more of the foregoing effects. | 12-23-2010 |
20110021622 | Stabilized Synthetic Brood Pheromone and Race-Specific Ratios of Components for Manipulating the Behavior and Physiology of Honey Bees - This invention relates to a 10-component stabilized synthetic honey bee brood pheromone and methods of stabilizing said pheromone by adding one or more antioxidants, thereby enabling the production and sustained use of commercial products based on that pheromone. The 11-component stabilized pheromone composition formed by adding the antioxidant tertiary-butyl hydroquinone to a synthetic blend of ethyl linoleate, ethyl linolenate, ethyl oleate, ethyl palmitate, ethyl stearate, methyl linoleate, methyl linolenate, methyl oleate, methyl palmitate and methyl stearate can be used in generic or race-specific ratios to manipulate the behavior and improve the performance of worker honey bees, resulting in overall increased vigor of the hive. | 01-27-2011 |
20110028542 | COMPOSITIONS FOR PREVENTION OR TREATMENT OF ANOREXIA-CACHEXIA SYNDROME AND USES THEREOF - A pharmaceutical composition for 1) increasing weight gain; and/or 2) decreasing weight loss; and/or 3) increasing appetite in a subject in need thereof, comprising purified β-caryophyllene together with a pharmaceutically acceptable carrier. Also provided are pharmaceutical compositions for use in the prevention or treatment of Anorexia-Cachexia Syndrome, the pharmaceutical composition comprising purified β-caryophyllene together with a pharmaceutically acceptable carrier. | 02-03-2011 |
20110046216 | STABLE COMPOSITIONS OF DEHYDROASCORBIC ACID - Stable liquid compositions containing the oxidized form of vitamin C known as dehydroascorbic acid are provided. The compositions comprise dehydroascorbic acid and a pharmacologically acceptable liquid organic polyol solvent for said dehydroascorbic acid, wherein said polyol solvent comprises about 50% or greater of the total weight of said composition. The compositions are useful as dietary supplements, skin-enhancers, concentrates, or research solutions. | 02-24-2011 |
20110105601 | COMPOSITIONS FOR USE IN TREATING OR PREVENTING METABOLIC STRESS-INDUCED LUNG INJURY AND METHODS FOR INCREASING PHYSICAL CAPACITY OF MAMMALIAN LIVESTOCK - The present invention relates to a composition comprising (i) choline and (ii) a compound selected from the group consisting of palmitate, vitamin C and vitamin E for use in treating or preventing metabolic stress-induced lung injury and a method for increasing physical capacity of mammalian livestock comprising administering to the mammalian livestock the above composition. | 05-05-2011 |
20110160299 | COMPOSITION AND METHOD - A companion pet diet meeting ordinary nutritional requirements for an aged pet and further comprising a sufficient amount of antioxidant or mixture thereof, to inhibit the deterioration of the mental capacity of an aged companion pet. | 06-30-2011 |
20110196030 | TOCOTRIENOL ESTERS - Esters of tocotrienols having pharmacological activities pertinent to the treatment of breast cancer and other forms of cancer are disclosed herein. Among those compounds is (Z)-4-oxo-4-((R)-2,5,7,8-tetramethyl-2-((3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl)chroman-6-yloxy)but-2-enoic acid. Tocotrienol esters were used to inhibit the growth and migration of +SA mammary epithelial cells and highly metastatic human breast cancer MDA-MB-231 cells respectively. | 08-11-2011 |
20110196031 | COMPOSITIONS AND METHODS FOR TREATING VARICOSE VEINS - The present invention provides compositions and methods for preventing or treating diseases and disorders, the composition comprising vitamin C, vitamin E, and at least one of an omega-3 fatty acid and an omega-6 fatty acid. | 08-11-2011 |
20110213025 | Catheter Lock Solutions Utilizing Tocopherol and Mid-Chain Fatty Acids - Methods, compositions and kits are disclosed for infusing a hydrophobic catheter lock solution into an indwelling catheter. The combination of a tocopherol compound and at least one saturated mid-chain fatty acid provides a broad spectrum antimicrobial solution with optimal viscosity for effectively locking a catheter. The lock can effectively reduce or eliminate the risk of infection and prevents tainting the catheter, particularly clotting and thrombus in intravascular and extravascular catheters. The potential for this discovery is for maintaining or reestablishing the viability of an intravascular or extravascular catheter, as well as topical formulations for promoting healing. | 09-01-2011 |
20110218241 | ANTIVIRAL EPICATECHINS, EPICATECHIN OLIGOMERS, OR THIOLATED EPICATECHINS FROM THEOBROMA CACAO FOR TREATMENT OF GENITAL WARTS - Epicatechins, Epicatechin Oligomers, or Thiolated Epicatechins are applied (A) directly to a genital wart in the form of a cream, ointment, paste or solution, (B) directly to the genital wart wherein such cream, ointment, paste or solution contains as an additional active ingredient a skin permeabilizing agent, (C) following electrosurgical resection or removal of the genital wart in such form of a cream, ointment, paste or solution, (D) following chemical resection or extirpation of the genital wart in such form, (E) following surgical resection or removal of the genital wart in such form, wherein said Epicatechins, Epicatechin Oligomers, or Thiolated Epicatechins both provide antiviral activity against multiple strains of human papilloma virus (HPV) and promote healing following resection polymers contained in a vehicle. Disclosed are the compositions, therapeutical kits containing such composition, methods of treatment using such composition, and methods of enhancing the stability of such composition. | 09-08-2011 |
20110237661 | Supplement Composition and Method of Use - The present invention relates to a dietary supplement composition made of: linolinic expeller pressed soybean oil in the range of 65%-85%, Omega 3 (18/12) fish oil 15%-35%, and 1%-20% alpha-tocopherol and a method to use this composition to supplement the diet of a domestic animal, such as a canine or an equine. | 09-29-2011 |
20110251273 | COMPOSITION AND METHOD OF TREATING SKIN CONDITIONS - This invention relates to compositions containing a retinoid and use of the compositions for treating skin conditions. | 10-13-2011 |
20110251274 | Natural Vitamin E Compositions with Superior Antioxidant Potency - Compositions for increased antioxidant potency of natural vitamin E (d-alpha-tocopherol), comprising alpha-, beta-, delta-, and gamma-forms of tocopherols and tocotrienols are disclosed. All of these compositions provide 400 International Units (IU), based on one mg of d-alpha-tocopherol provides 1.49 IU. These compositions showed antioxidant activities superior to natural d-alpha-tocopherol. These compositions are designed to provide protection of the cell membrane lipid layer, and protection against heart disease, cancer, and eye disease. | 10-13-2011 |
20110281941 | COMBINATION OF LYCOPENE, POLYPHENOL, AND VITAMINS FOR THE CARE OF KERATIN MATERIALS - The present invention relates to the cosmetic use, by the oral route, of a combination of lycopene, of vitamin C, of vitamin E and of at least one polyphenol compound derived from pine bark as active ingredient intended for maintaining and/or restoring the biomechanical properties of keratinous materials, and notably of the skin. | 11-17-2011 |
20110288165 | NOVEL LIPID COMPOSITION FOR THE TREATMENT OF SKIN PROBLEMS IN COMPANION ANIMALS - The present invention provides lipid compositions comprising linolenic acid (LA), alpha-linolenic acid (ALA), stearidonic acid (SDA) and gamma linolenic acid (GLA), said LA and ALA in a ratio of about less than 2:1 LA:ALA. The compositions find use in for improving, treating, or preventing a condition selected from the group consisting of: eczema, dry skin, flaky skin, pruritus, pyotraumatic dermatitis, furunculosis, dry paw pads, rough paw pads, chapped paw pads, paw pad durability, dry rhinarium, chapped rhinarium, split claws, brittle claws, rashes, hairless spots, hot spots, symmetrical lupoid onychodystrophy, skin ulceration, skin crusting, reddening of skin between toes, external ear infection, and nutritional dermatosis. | 11-24-2011 |
20120004297 | Agent for alleviating vascular failure - An agent for alleviating, treating and preventing vascular failure and a vascular endothelial cell-protecting agent characterized by containing, as an effective ingredient, at least one active oxygen scavenger such as astaxanthin and tocotrienols; and a food, a drink and an animal feed having an effect of alleviating, treating and preventing vascular failure and an effect of protecting vascular endothelial cells characterized by containing, as the effective ingredient, at least one active oxygen scavenger such as astaxanthin and tocotrienols. | 01-05-2012 |
20120010280 | OPHTHALMIC COMPOSITIONS BASED ON POLYUNSATURATED OMEGA-3 AND OMEGA-6 FATTY ACIDS - The invention concerns topical compositions for the prevention and treatment of ocular pathologies, in particular inflammatory keratites and conjunctivites and dry eye syndrome, containing as active ingredients polyunsaturated fatty acids of the types omega-3 and omega-6, and specifically EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) and GLA (γ-linolenic acid), mixed with vitamin E acetate and formulated in a stable composition in hydrogel, i.e. in dispersed form in an aqueous vehicle containing one or more gelling polymers. The proposed compositions are particularly indicated for use as artificial tears. | 01-12-2012 |
20120029068 | TRANSDERMAL FLUID - The present invention relates to a transdermal fluid. The transdermal fluid containing an active amount of a tocotrienol is described, useful for the treatment or prevention of a cancer or a tumour or an inflammatory disorder, particularly breast cancer. The fluid can be used either in combination with known medication or exclusively. | 02-02-2012 |
20120046354 | ANTI-OXIDANT LOZENGES FOR THE PREVENTION AND TREATMENT OF RADIATION INDUCED MUCOSITIS, PRECANCEROUS LESIONS, ORAL CANCER AND OTHER ORAL CAVITY MUCOSAL DISORDERS - A method for treating or preventing oral cavity mucosal disorders, comprising a step of providing a lozenge containing an antioxidant selected from the group of Vitamin A, Vitamin C, Vitamin E; and other ingredients and a step of placing the lozenge within the oral cavity for a period of time required for dissolution of the lozenge. | 02-23-2012 |
20120108658 | OPHTHALMIC COMPOSITION - Disclosed is an ophthalmic composition which is characterized by containing (A) a vitamin A, (B) a polyoxyethylene polyoxypropylene glycol, and (C) an oil component that is selected from the group consisting of castor oil, soybean oil, sesame oil, peanut oil, olive oil, almond oil, wheat germ oil, corn oil, rapeseed oil, sunflower oil, purified lanolin and gel hydrocarbon. | 05-03-2012 |
20120122969 | TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH TOCOTRIENOLS OR TOCOTRIENOL ENRICHED EXTRACTS - Methods of treating or suppressing Pervasive Developmental Disorders (PDDs) including; Autistic Disorder, Asperger's Disorder, Childhood Disintegrative Disorder (CDD), Rett's Disorder, and PDD-Not Otherwise Specified (PDD-NOS) comprising administering to a subject in need thereof a therapeutically effective amount of a tocotrienol, a tocotrienol ester, a tocotrienol ether, a tocotrienol enriched extract or mixtures thereof. | 05-17-2012 |
20120190737 | Fatty Acid Formulations and Methods of Use Thereof - The present invention provides dietary formulations comprising polyunsaturated fatty acids and vitamin E. The present invention further provides methods of treating various conditions, generally involving administering to an individual in need thereof an effective amount of a subject dietary formulation. | 07-26-2012 |
20120252888 | Compositions and Methods for Treating Neurologic Disorders - The present invention relates to compositions comprising DHA, EPA, LA and GLA. The compositions may further comprise other omega-3 PUFAs, MUFAs, SFAs, gamma tocopherol, Vitamin A and Vitamin B. The compositions are useful for treating neurologic disorders. The compositions are administered chronically for the prevention and/or treatment of multiple sclerosis (MS) and other degenerative diseases. | 10-04-2012 |
20120264822 | METHOD OF IMPROVING ANIMAL TISSUE QUALITY BY SUPPLEMENTING THE ANIMAL DIET WITH OLEIC ACID AND SELECTED TOCOLS - A novel method for improving the meat quality of an animal is provided. The method comprises feeding the animal a diet supplemented with oleic acid and selected tocols in amounts effective to improve the meat quality. The method may be practiced on non-ruminants and ruminants. | 10-18-2012 |
20120289590 | HAIR COSMETIC COMPOSITION - A hair cosmetic composition including an exfoliating agent, an antioxidant, and an antibacterial agent. The hair cosmetic composition is noncomedogenic and nonacnegenic. | 11-15-2012 |
20120329864 | SYNERGISTIC EFFECT OF TOCOTRIENOLS AND CURCUMIN - A transdermal fluid is provided wherein the main ingredient is tocotrienol, and curcumin is added to enhance the anti-cancer effects of tocotrienols. The composition is useful for the treatment or prevention of a cancer, a tumour or an inflammatory disorder, particularly breast cancer. | 12-27-2012 |
20130041024 | Methods for the Diagnosis, Control and Prophylaxis of Inflammation and Mitigation of Inflammatory Conditions in Canines - The invention relates to methods of diagnosis, control and prophylaxis of inflammation and mitigation of inflammatory conditions, particularly arthritis and joint pain, in canines, comprising measuring inflammatory biomarkers wherein elevated levels of the biomarkers in blood correlates to reduced inflammation and reduced levels in blood correlates to increase level in the tissues. The invention further provides a method to treat or control inflammation comprising administering a diet comprising increased levels of one or more of DHA, EPA, vitamin C, vitamin E, and/or L-carnitine. | 02-14-2013 |
20130079395 | NOVEL PROCESS - The present invention provides a process for the production of an oil in water emulsion comprising the step of a) introducing an oil phase into a mixing device by applying a positive pressure in the oil phase containing tank. | 03-28-2013 |
20130096190 | PERFLUOROCARBON GEL FORMULATIONS - A perfluorocarbon gel composition is disclosed with numerous uses including topical medical and cosmetic uses. | 04-18-2013 |
20130116314 | METHOD OF MAINTAINING OR IMPROVING THE SKIN HEALTH OF AN ANIMAL COMPRISING ADMINISTERING AS A DIETARY SUPPLEMENT A COMPOSITION COMPRISING FLAX SEED OIL AND GAMMA LINOLENIC ACID - A phytochemical composition for use as a veterinary dietary supplement comprising alpha linolenic acid (ALA) and up to 10% gamma linolenic acid (GLA). Preferably the ALA source is flax seed oil and GLA is sourced from borage oil. | 05-09-2013 |
20130178518 | Contact Lenses Containing Carotenoid And Method For Making Same - The instant invention pertains to a method for producing contact lenses with improved oxidative stability of Carotenoids in the contact lens. The method of the invention involves adding a vitamine E material into a contact lens in an amount sufficient to reduce oxidative degradation of Carotenoids in the lens by at least about 30% in comparison with an identical contact lens without the vitamin E material. | 07-11-2013 |
20130178519 | EXTRACTION OF VITAMIN E FROM PLANT MATTER - A process for the extraction of Vitamin E from annatto plant matter is disclosed wherein annatto seed matter is subjected, before extraction, to acidification using amla fruit matter. After the acidification, the mixture of the two plant matters is extracted by water. The acidification converts the vitamin E compounds in the plant matter into more water-soluble forms thus enhancing the vitamin yield. More of the vitamin is obtained in the ester form than in the form of vitamin alcohols. Processing time is reduced. | 07-11-2013 |
20130274324 | COMPOSITIONS OF FAT-SOLUBLE ACTIVE INGREDIENTS CONTAINING PLANT PROTEIN-SOY POLYSACCHARIDE COMPLEXES - The present invention relates to compositions comprising a) 0.1 to 70 weight-% based on the composition of one or more fat-soluble active ingredients; b) one or more plant protein(s) chosen from the group of proteins suitable for food application; and c) one or more soy soluble polysaccharide(s); wherein the sum of the amount of protein(s) and the amount of polysaccharide(s) represents 10 to 85 weight-% based on the composition in dry matter and, wherein the weight ratio of protein(s) to polysaccharide(s) is chosen like 1:b with the proviso that b is comprised between 0.5 and 15. | 10-17-2013 |
20130296420 | NATURAL LYCOPENE CONCENTRATE AND METHOD FOR PRODUCTION THEREOF - Natural lycopene concentrate obtained from a plant structure after alkalinization, solid-liquid separation, acidification and a second solid-liquid separation. The concentrate obtained is highly bioavailable and water-soluble at room temperature. | 11-07-2013 |
20130317096 | SYNERGISTIC INTERACTION OF AT LEAST ONE VITAMIN E COMPONENT AND TYROSINASE INHIBITORS FOR DERMATOLOGICAL APPLICATIONS - The present invention is directed to a method of treating a dermatological condition or preventing a dermatological condition from occurring or for altering the pigmentation of the skin by administering to a patient a pharmaceutically effective amount of a composition comprising at least one Vitamin E component and at least one additional component different from the Vitamin E component that has anti-tyrosinase activity and/or anti-melanogenesis activity. The present invention is further directed to a pharmaceutical composition comprising at least one Vitamin E component and at least one additional component different from the Vitamin E component that has anti-tyrosinase activity and/or anti-melanogenesis activity. | 11-28-2013 |
20130317097 | STABLE COMPOSITIONS OF DEHYDROASCORBIC ACID - The invention relates to stable liquid compositions containing the oxidized form of vitamin C known as dehydroascorbic acid (DHAA). The compositions comprise DHAA and a pharmacologically acceptable liquid organic polyol solvent. The polyol solvent comprises about 50% or greater of the total weight of the composition. The compositions are useful as dietary supplements, skin-enhancers, concentrates, or research solutions. | 11-28-2013 |
20130317098 | PROTECTIVE HYDROCOLLOID FOR ACTIVE INGREDIENTS - (Modified) sorghum protein is used as novel protective hydrocolloid for active ingredients, especially fat-soluble active ingredients and/or colorants. Included are compositions comprising (modified) sorghum protein and at least one active ingredient and to their manufacture, as well as to the (modified) sorghum protein itself and its manufacture. These compositions are used for the enrichment, fortification and/or coloration of food, beverages, animal feed, personal care or pharmaceutical compositions, and to food, beverages, animal feed, personal care and pharmaceutical compositions containing such a (modified) sorghum protein and such a composition, respectively. | 11-28-2013 |
20130338221 | PHOTOAGING PROTECTIVE COMPOSITION CONTAINING CHROMENES DERIVED FROM SARGASSUM HORNERI - There is provided a photoaging protective composition having an effect of protecting photoaging on skin cell, the composition including chromenes derived from | 12-19-2013 |
20130345301 | SUPPLEMENT COMPOSITION AND METHOD OF USE - The present invention relates to a dietary supplement composition made of: linolenic expeller pressed soybean oil in the range of 65%-85%, Omega 3 (18/12) fish oil 15%-35%, and 1%-20% alpha-tocopherol and a method to use this composition to supplement the diet of a domestic animal, such as a canine or an equine. | 12-26-2013 |
20140148506 | DRUG ELATING SILICONE GEL SHEETING FOR WOUND HEALING AND SCAR REDUCTION - Provided are compositions of various silicone compounds loaded with active pharmaceutical agents, which are suitable for promoting the healing of skin wounds and the reduction or prevention of scarring. | 05-29-2014 |
20140179776 | Skin Cleansing Cosmetic Composition Containing Vegetable Oils, Method For Producing Same And Use Thereof - The present invention relates to a cosmetic composition, particularly indicated for cleaning the skin, which comprises a plant oil portion comprising:
| 06-26-2014 |
20140200268 | Composition and Method for Treating Dry Eye Syndrome - The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of α-tocopheryl acetate; α-tocopheryl acetate and about 0.5% aqueous component; or α-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient. | 07-17-2014 |
20140315995 | Antioxidant Compositions and Methods of Using the Same - The invention provides non-irritating, stable topical compositions including at least Vitamin C, Vitamin E and a polyphenol antioxidant. Such compositions can be used to facilitate the prevention or treatment of free oxygen, nitrogen, and/or other free radical related skin damage. Also provided are methods for modifying free radical damage to skin by administering such compositions in an amount sufficient to treat and/or prevent free radical damage to the skin. | 10-23-2014 |
20140357709 | PROTECTIVE HYDROCOLLOID FOR ACTIVE INGREDIENTS - (Modified) | 12-04-2014 |
20150025133 | NUTRITIONAL COMPOSITIONS INCLUDING RRR-ALPHA TOCOPHEROL AND POLYUNSATURATED FATTY ACIDS - Disclosed are nutritional formulas generally, and infant formulas specifically, including a combination of RRR-alpha tocopherol, LC-PUFAs, and optionally vitamin C. The combination enhances brain development and improves cognitive performance in an individual, and specifically in an infant. | 01-22-2015 |
20150051274 | SUPPLEMENT COMPOSITION AND METHOD OF USE - The present invention relates to a dietary supplement composition made of: linolenic expeller pressed soybean oil in the range of 65%-85%, Omega 3 (18/12) fish oil 15%-35%, and 1%-20% alpha-tocopherol and a method to use this composition to supplement the diet of a domestic animal, such as a canine or an equine. | 02-19-2015 |
20150290102 | TOPICAL SANITIZING FORMULATIONS AND USES THEREOF - Several embodiments disclosed herein relate to formulations having antimicrobial and/or sanitizing effects, and uses of the same. In particular, the formulations and methods of using same provide, in several embodiments, an immediate and a persistent antimicrobial effect against a broad spectrum of microorganisms. | 10-15-2015 |
20150359779 | COMPOSITION AND METHOD FOR TREATING DRY EYE SYNDROME - The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present embodiments provide for medicaments consisting of tocopherol or tocotrienol eyedrops. A single topical administration of tocopherol or tocotrienol eyedrops in the eyes of a subject suffering from dry eye alleviates symptoms for at least one day. In particular, the eyedrop medicament consists of α-tocopheryl acetate; α-tocopheryl acetate and about 0.5% aqueous component; or α-tocopheryl acetate, about 2.5% tocopherol emulsifier, and about 20% to about 30% aqueous excipient. | 12-17-2015 |
20160008318 | A COMPOSITION FOR ENHANCING NEWBORN INFANT COGNITIVE, BRAIN AND/OR CNS DEVELOPMENT AND METHOD OF USING SAME | 01-14-2016 |
20160022628 | INFANT NUTRITIONAL PRODUCT WITH RRR ALPHA-TOCOPHEROL - This invention relates to a method of improving CNS maturation in an infant by administering a mixture of natural tocopherols, wherein the composition contains an optimum tocopherol profile similar to that found in human breast milk, and can encompass a tocopherol profile from early stage to transitional to mature human breast milk. For ease of administration and maximized efficacy, the optimized mixture of natural tocopherols are typically delivered in an oral dosage form with a limited level of non-RRR alpha-tocopherols to maximize efficacy of the RRR alpha-tocopherol on stimulating post-natal CNS development. | 01-28-2016 |
20160038440 | Astaxanthin Anti-Inflammatory Synergistic Combinations - This invention is directed to compositions having synergistic combinations of astaxanthin with a tomato extract lycopene, and optionally with carnosic acid and/or lutein. More specifically, the present invention provides compositions having synergistic combinations of the aforementioned compounds, which may be used, inter alia, to inhibit/suppress inflammation via the suppression of the expression of anti-inflammatory mediators or via the suppression of the secretion of anti-inflammatory mediators from macrophages at a site of inflammation. | 02-11-2016 |
20160038459 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NATAL AND PRE-NATAL CONDITIONS WITH ALPHA-TOCOPHEROL - The present invention provides methods, compositions, and systems for preventing or reducing an allergic condition in an offspring by administering tocopherol to a mother pregnant or nursing the offspring, where the tocopherol in the composition is 98-100% unmodified natural d-alpha tocopherol, and less than 2% gamma tocopherol (e.g., undetectable levels of gamma tocopherol). In certain embodiments, a prenatal tablet or pill is provided composed of such tocopherol compositions in combination with folic acid, iron, and calcium. | 02-11-2016 |
20160106670 | Novel Process - The present invention provides a process for the production of an oil in water emulsion comprising the step of a) introducing an oil phase into a mixing device by applying a positive pressure in the oil phase containing tank. | 04-21-2016 |
20160106708 | USE OF ANTIOXIDANTS FOR THE TREATMENT OF COGNITIVE AND BEHAVIOURAL DISORDERS IN INDIVIDUALS WITH FRAGILE X SYNDROME - The invention relates to the use of antioxidants such as, ascorbic acid (Vitamin C), Tocopherol (Vitamin E), vitamin A and polyphenols, for the treatment of cognitive and behavioural disorders in patients with Fragile X syndrome. Specifically, the invention relates to the use of said antioxidants in a pre-determined concentration in a therapeutic doses, in order to obtain the greatest amount of antioxidants possible in all the tissues of the organism, so as to eliminate the excess free radicals produced in the cells and to treat the aforementioned cognitive and behavioural disorders in patients with Fragile X syndrome. | 04-21-2016 |
20160151260 | Skin Treatments Containing Carboxylic Acid-Substituted Idebenone Derivatives and Methods of Preparation and Use Thereof | 06-02-2016 |
20160193340 | NOVEL USES OF ALKYL POLYGLYCOSIDES FOR SOLUBILISING VITAMIN E IN WATER; COMPOSITIONS COMPRISING SAME | 07-07-2016 |
20190142791 | USE OF RICE BRAN OIL DISTILLATE EXTRACT FOR PREVENTION AND MITIGATION OF THE EFFECTS OF RADIATION | 05-16-2019 |
20190144413 | TOCOTRIENOL DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHOD OF USE IN 5-LIPOXYGENASE RELATED DISEASES | 05-16-2019 |