Entries |
Document | Title | Date |
20080300683 | PROSTHETIC DEVICE AND METHOD OF MANUFACTURING THE SAME - A knitted prosthetic device has at least two knitted sections, where each knitted section has at least one row of fiber. The knitted prosthetic device also has at least one intra-articular section disposed between the at least two knitted sections. In addition, the at least one intra-articular section has at least one single continuous fiber traversing the at least one intra-articular section and the at least two knitted sections, where the at least one single continuous fiber forms a plurality of traverses extending between the at least two knitted sections. In particular, embodiments may be used as ligament prostheses by anchoring each of the at least two knitted sections to a bone section of a patient. Such embodiments may be constructed from a strong polymer, preferably, but not limited to, silk, where the polymer provides ligament support but bioresorbs as load bearing responsibilities are transferred to tissue resulting from in-growth. | 12-04-2008 |
20090069893 | Oriented Collagen-Based Materials, Films and Methods of Making Same - In general, the present invention is related to collagen compositions and thin films, and to methods of making and using the same. In some embodiments, the present invention is directed to “uniaxial pattern” or “linear pattern” collagen materials, compositions and thin films, and methods of making. | 03-12-2009 |
20090076604 | ARTIFICIAL LIGAMENTS FOR JOINT APPLICATIONS - A ligament incorporated into a prosthetic joint exhibiting a plasticized, elongated and deformable material. A fibrous material is internally disposed within the deformable material, the fibrous material terminating in first and second enlarged bead portions arranged in proximity to enlarged pocket defined ends associated with the deformable materials. First and second bones define a joint region therebetween, the deformable end pockets and bead portions being inserted through associated holes defined in joint proximate locations associated with the bones, so that actuation of a projection location of the fibrous material causes the bead portions to outwardly deflect the end pockets, resulting in the ligaments being anchored in place between the bones. | 03-19-2009 |
20090287307 | Orthopaedic Implant and Prosthesis Systems, Devices, Instruments and Methods - The present invention provides a replacement ligament comprising first and second ends, two or more securing portions for securing said ligament to a portion of bone material and a body portion comprising a first component having a first, higher, elongation per unit load characteristic; and a second component having a second, lower, elongation per unit load characteristic. The first and second components are between said two or more securing portions and arranged in load series such that initial, lower, loading is reacted by said first component and subsequent, higher, loading is reacted by said second component. | 11-19-2009 |
20100049319 | SINGLE-TUNNEL DOUBLE BUNDLE ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION - The present invention provides a method of performing anterior cruciate ligament replacement. Specifically, a graft tissue is harvested from a patient and single tunnels are prepared in each of the tibia and the femur of the patient. The graft is secured in the femoral tunnel and separated into an anterior cruciate medial bundle and a anterior cruciate posterior lateral bundle. The bundles are inserted through the tibial tunnel. During insertion the posterior lateral bundle is positioned in a posterior lateral position in the tibial tunnel while the anterior cruciate medial bundle is positioned in an anterior cruciate medial position in the tibial tunnel. The anterior cruciate medial bundle is then tensioned while the patient's knee is in approximately 90 degrees of flexion, and the posterior lateral bundle is tensioned while the patient's knee is approximately in full extension. Each of the bundles is then secured in the tibial tunnel. | 02-25-2010 |
20100121447 | METHOD FOR REPLACING A LIGAMENT IN A KNEE - A method of providing a replacement anterior cruciate ligament (ACL) provides a tibial tunnel and at least one femoral tunnel for receiving the replacement ligament, the femoral and tibial tunnels not being colinear but rather in an orientation that more closely mimics the natural ACL. The femoral tunnel is formed through the anterior medial portal. A cross pinning guide having a femoral rod for insertion into the femoral tunnel, a spaced apart arc shaped track and a guide block having one or more bores aligned with the femoral rod whereby an instrument inserted through one of the bores creates a pilot hole for the cross pin which intersects the femoral tunnel and an appropriate angle thereof which avoids ligaments and other sensitive tissue can be selected by adjusting the guide block along the track. | 05-13-2010 |
20100121448 | METHOD AND APPARATUS FOR FIXING A GRAFT IN A BONE TUNNEL - A method and apparatus for fixing a ligament in a bone tunnel by cross-pinning the ligament in the bone tunnel. | 05-13-2010 |
20100174368 | PLATELET-DERIVED GROWTH FACTOR COMPOSITIONS AND METHODS FOR THE TREATMENT OF TENDON AND LIGAMENT INJURIES - The invention provides compositions and methods for treatment of tendon and ligament injuries and/or repair of damaged tendons and ligament. The invention provides compositions comprising a biocompatible matrix and platelet-derived growth factor (PDGF). | 07-08-2010 |
20100211173 | ARTICULAR CARTILAGE, DEVICE AND METHOD FOR REPAIRING CARTILAGE DEFECTS - The articular cartilage according to the invention is made of pure cartilage and is provided with incisions ( | 08-19-2010 |
20100234949 | DEVICE FOR ELASTIC LIGATURE OF TISSUES - A device for elastic ligature of tissues comprises: a first and a second element, one of which exhibits a support portion for at least a rubber ring, the elements being slidably coupled to one another such that a reciprocal sliding between the elements determines a release of a rubber ring from the support portion; a trigger, manually manoeuvrable by an operator and acting on at least the second element for realising a reciprocal sliding between the elements; a connecting portion, connected to the trigger and to the second element and being elastically deformable in order to enable a reciprocal change of orientation between the trigger and the second element. | 09-16-2010 |
20110046732 | STRUCTURALLY MODIFIED ACELLULAR TISSUE ENGINEERING SCAFFOLDS AND METHODS OF PRODUCTION - Methods are provided for producing a bioscaffold from natural tissues by oxidizing a decellularized tissue to produce a bioscaffold having pores therein. The pore size and porosity is increased to better accommodate intact cells so that live cells can better infiltrate and inhabit the bioscaffold. The bioscaffold may be freeze-dried or lyophilized, sterilized and (optionally) aseptically packaged for subsequent use. A further aspect of the present invention is a bioscaffold produced by the processes described herein. Methods of treatment using the bioscaffold as a graft or as a biomedical implant for implantation are also provided. Also provided are methods of seeding a bioscaffold with mammalian cells, wherein the seeding carried out either in vitro or in vivo, and wherein a bioscaffold produced as described herein is utilized for said seeding. | 02-24-2011 |
20110066241 | DEMINERALIZED CANCELLOUS BONE SCAFFOLDS - The present invention provides a cancellous bone scaffold to use in the replacement or repair of connective tissue such as ligaments and tendons. The cancellous bone scaffold has a fully demineralized segment with at least one adjacent mineralized end segment. | 03-17-2011 |
20110238178 | TISSUE REPAIR SCAFFOLD - The present invention provides a tissue repair scaffold comprising a secondary fibre bundle, the secondary fibre bundle comprising a plurality of primary fibre bundles, each primary fibre bundle comprising a plurality of fibres, wherein the fibres comprise a biocompatible polymer. In embodiments the biocompatible polymer is polycaprolactone (PCL) (also known as poly-ε-caprolactone) and the average diameter of the fibres is less than 1 μm. The scaffold is particularly adapted for tendon repair. In vivo mouse studies demonstrate that tendon repair can be achieved with normal ambulation returning after 24-48 hours. The scaffolds were easy to handle during surgery, being non-slippery and easy to suture in place. | 09-29-2011 |
20110276137 | TUBULAR IMPLANTABLE CORD - A surgical cord ( | 11-10-2011 |
20110282447 | COMPRESSIBLE TUBES FOR PLACING IMPLANTS AND RELATED MEDICAL KITS AND METHODS OF USING SAME - Medical delivery devices include a needle and a flexible compressible impermeable tube attached to the needle. The compressible tube has an open interior channel. The device is adapted to releasably hold a length of a medical implant in the open interior channel of the tube. The medical implant can be slidably inserted into the interior channel of the tube and is loosely held by the tube. | 11-17-2011 |
20110282448 | METHODS OF MAKING COLLAGEN FIBER MEDICAL CONSTRUCTS AND RELATED MEDICAL CONSTRUCTS, INCLUDING TUBES FOR AUTO AND/OR ALLO-GRAFTS - The disclosure describes methods of winding collagen fiber to make medical constructs and related collagen fiber tube and patch devices. | 11-17-2011 |
20110319993 | TENDON OR LIGAMENT TISSUE ENGINEERING - This document relates to methods and materials involved in tendon or ligament tissue engineering. For example, methods and materials for generating a composite of acellular tendon or ligament allograft slices seeded with cells and bundled into a graft for tissue repair are provided. | 12-29-2011 |
20120071975 | DEVICE AND METHOD FOR ASSISTING IN FLEXOR TENDON REPAIR AND REHABILITATION - A device and method used to protect at least one end of a severed flexor tendon from contacting the edge of a flexor tendon pulley. The device, in one embodiment, can include a body forming a complete perimeter around at least a portion of a cavity passing through the device. The body of the device includes a first portion that is adapted for insertion through the passage of a flexor tendon pulley, a second portion that adapted funnel the severed flexor tendon into the cavity, and a perforation that extends the length of the body that is adapted to be torn along the length thereof to afford removal of the device from around the previously-severed flexor tendon. | 03-22-2012 |
20120179252 | PROSTHETIC DEVICE AND METHOD OF MANUFACTURING THE SAME - A knitted prosthetic device has at least two knitted sections, where each knitted section has at least one row of fiber. The knitted prosthetic device also has at least one intra-articular section disposed between the at least two knitted sections. In addition, the at least one intra-articular section has at least one single continuous fiber traversing the at least one intra-articular section and the at least two knitted sections, where the at least one single continuous fiber forms a plurality of traverses extending between the at least two knitted sections. In particular, embodiments may be used as ligament prostheses by anchoring each of the at least two knitted sections to a bone section of a patient. Such embodiments may be constructed from a strong polymer, preferably, but not limited to, silk, where the polymer provides ligament support but bioresorbs as load bearing responsibilities are transferred to tissue resulting from ingrowth. | 07-12-2012 |
20120179253 | PROSTHETIC DEVICE AND METHOD OF MANUFACTURING THE SAME - A knitted prosthetic device has at least two knitted sections, where each knitted section has at least one row of fiber. The knitted prosthetic device also has at least one intra-articular section disposed between the at least two knitted sections. In addition, the at least one intra-articular section has at least one single continuous fiber traversing the at least one intra-articular section and the at least two knitted sections, where the at least one single continuous fiber forms a plurality of traverses extending between the at least two knitted sections. In particular, embodiments may be used as ligament prostheses by anchoring each of the at least two knitted sections to a bone section of a patient. Such embodiments may be constructed from a strong polymer, preferably, but not limited to, silk, where the polymer provides ligament support but bioresorbs as load bearing responsibilities are transferred to tissue resulting from ingrowth. | 07-12-2012 |
20120226354 | METHOD OF USING AN IMPLANT FOR TREATMENT OF LIGAMENTS AND TENDONS - A method of treating a ligament or tendon according to the present invention can include inserting a tissue-generating implant into the ligament or tendon to thereby treat the defect. The tissue-generating implant has a plurality of microparticles. The microparticles subsequently form a biological scaffold which operates at least as partial connective tissue in the ligament or tendon giving structural support during regrowth. | 09-06-2012 |
20120226355 | TENODESIS IMPLANT AND INSERTER AND METHODS FOR USING SAME - The present invention provides a novel split barbed fixation device for tenodesis, soft tissue reattachment of tendons and ligaments to bones. The insertion device is adapted for an entirely arthroscopic approach while achieving fixation strength with ultimate pullout resistance comparable to interference screws. The device includes an integrated tendon grasper that provides for easy manipulation of the tendon arthroscopically while eliminating the need for external whip stitching of the tendon, thereby reducing preparation time. The device further includes elements that prevent the fixation implant from being destabilized or rotating during deployment and manipulation, including: a depth limiting sheath, a first implant retainer, a first implant retaining step, a tendon grasping needle tube, and an implant keyway for mating the implant to the tube. The implant itself comprises two separate portions mating along a diagonal and having barbed surface features in opposite directions, only one of which contacts the tendon. | 09-06-2012 |
20120259415 | STRUCTURALLY MODIFIED ACELLULAR TISSUE ENGINEERING SCAFFOLDS AND METHODS OF PRODUCTION - Methods are provided for producing a bioscaffold from natural tissues by oxidizing a decellularized tissue to produce a bioscaffold having pores therein. The pore size and porosity is increased to better accommodate intact cells so that live cells can better infiltrate and inhabit the bioscaffold. The bioscaffold may be freeze-dried or lyophilized, sterilized and (optionally) aseptically packaged for subsequent use. A further aspect of the present invention is a bioscaffold produced by the processes described herein. Methods of treatment using the bioscaffold as a graft or as a biomedical implant for implantation are also provided. Also provided are methods of seeding a bioscaffold with mammalian cells, wherein the seeding carried out either in vitro or in vivo, and wherein a bioscaffold produced as described herein is utilized for said seeding. | 10-11-2012 |
20120271414 | PLUG COMPONENTS FOR BONE TUNNEL - A component for satisfactorily plugging a bone tunnel formed in surgery such as ACL reconstruction by regenerating bone in a space portion of the bone tunnel (e.g., a bone tunnel for an arthroscope), is provided in order to solve the problems in the conventional technologies. The plug component is made of a calcium phosphate-based material, comprises a porous part having a porosity of 50 to 85%, and has a cylindrical shape such that one of its bottom surfaces forms an angle of 30 to 60 degrees to its central axis. | 10-25-2012 |
20120283829 | FAN FOLDED FASCIA LATA FOR CRUCIATE LIGAMENT SUBSTITUTION AND METHOD AND APPARATUS FOR MAKING THE SAME - Cruciate ligament substitutes are formed using fan-folded fascia lata grafts. Devices of making the same and methods of making and using the same are described herein. The fan-folded fascia lata cruciate ligament substitutes disclosed herein are used in a single-loop fashion and have surprisingly exhibited load to failure and stiffness values that compare favorably with conventional grafts, including tibialis anterior, tibialis posterior, peroneus longus, and bone-patellar tendon-bone (BPTB) half-patella specimens. It has been demonstrated that single-loop, fan-folded fascia lata sheets can exhibit mechanical properties that compare favorably with existing cruciate ligament grafts. An apparatus for handling a fascia lata sheet can include a first and a second removable anchoring member. A method of producing a cruciate ligament substitute can include providing a fascia lata sheet secured in a fan-folded orientation with at least one removable anchoring member, and securing the fan-folded fascia lata in a fan-folded orientation with at least one permanent anchoring member. | 11-08-2012 |
20120323323 | MICRO-ALLOYED POROUS METAL HAVING OPTIMIZED CHEMICAL COMPOSITION AND METHOD OF MANUFACTURING THE SAME - A micro-alloyed porous metal is disclosed having an optimized chemical composition to achieve targeted mechanical properties for use as an orthopaedic implant and a cell/soft tissue receptor. The porous metal may achieve a targeted compressive strength and a targeted ductility, for example. These targeted mechanical properties may allow the porous metal to be densified to a low relative density. | 12-20-2012 |
20130041464 | POSITIONING SYSTEMS AND METHODS FOR IMPLANTING AN ENERGY ABSORBING SYSTEM - Positioning instruments and related methods are described for implanting an energy absorbing system for treating joints. The positioning instruments and methods allow the energy absorbing system to be positioned at a joint such that the desired motion will occur for the particular design of a particular energy absorbing system which is to be implanted. The positioning instruments include a locating instrument for locating an anatomical feature and a target location for implantation of the energy absorbing system, a verification instrument for verification of the target location, a placement guide for guiding placement of a part of the energy absorbing system, and positioning device for aligning portions of the energy absorbing system. | 02-14-2013 |
20130123920 | DEVICE FOR TENDON AND LIGAMENT TREATMENT - Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include acellular arterial tissue matrices that facilitate regrowth of the damaged tissue. | 05-16-2013 |
20130172997 | METHODS AND APPARATUS FOR DELIVERING AND POSITIONING SHEET-LIKE MATERIALS IN SURGERY - An implant delivery system for delivering a sheet-like implant is disclosed. The implant delivery system includes a distal guidewire port for receiving the proximal end of guidewire after the guidewire distal end has been affixed to a first point on bone or other tissue. The implant delivery system is tracked over the guidewire to a selected position defined by the guidewire attachment. The device includes an implant spreader assembly disposed proximate the distal end of a delivery shaft. The implant spreader assembly includes a first arm and a second arm. The arms are coupled to the delivery shaft such that the first arm and second arm are moveable between a closed position and an open position. When pivoting to the open position the distal end of each arm travels in a generally transverse direction to spread a sheet-like implant. | 07-04-2013 |
20130345810 | BAND-LIKE STRUCTURE FOR THE AUGMENTATION OF A LIGAMENT - The invention relates to a band-like structure for the augmentation of a ligament, comprising a central section for fastening to an organ of the true pelvis, said central section having a central knit fabric with a central warp direction, a lateral section for fastening to a suspension surface and a plurality of threads, which are connected to the central section and the lateral section. It is proposed that the central knit fabric comprises the plurality of threads. | 12-26-2013 |
20140052247 | Placental tissue grafts modified with a cross-linking agent and methods of making and using the same - Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of chorion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts. | 02-20-2014 |
20140236295 | METHOD FOR MODIFYING BIOCOMPATIBILITY CHARACTERISTICS OF A SURFACE OF A BIOLOGICAL MATERIAL WITH GAS CLUSTER ION BEAM - A method for preparing a biological material for implanting provides irradiating at least a portion of the surface of the material with an accelerated Neutral Beam. | 08-21-2014 |
20140309738 | Membrane-Scaffold Composites for Tissue Engineering Applications - Collagen-glycosaminoglycan membrane shell scaffold core composites for connective tissue engineering that avoids aspects of the typical tradeoff between mechanical properties (i.e. modulus, failure strength) and bioactivity (i.e., permeability and porosity) for porous tissue engineering scaffolds. The relative density of the collagen glycosaminoglycan scaffold core can be about 0.5 to about 0.95 while the membrane shell can be about 0.001 to 25 about 0.2. The core-shell composite can be tubular and the composite can have a diameter of about 1 mm to about 20 mm. The collagen glycosaminoglycan membrane shell can be perforated with about 25 to about 1000 micrometers openings or alternatively can be embossed with any range of pattern features from about 25 to about 1000 micrometers in size. The porous collagen glycosaminoglycan scaffold core can be populated with cells such as adult or embryonic stem cells, tenocytes, osteoblasts, nerve cells, cardiac cells, myocytes, fibroblasts or combinations thereof. | 10-16-2014 |
20140371853 | TENDON REPAIR IMPLANT AND METHOD OF ARTHROSCOPIC IMPLANTATION - A tendon repair implant for treatment of a partial thickness tear in the supraspinatus tendon of the shoulder is provided. The implant may incorporate features of rapid deployment and fixation by arthroscopic means that compliment current procedures; tensile properties that result in desired sharing of anatomical load between the implant and native tendon during rehabilitation; selected porosity and longitudinal pathways for tissue in-growth; sufficient cyclic straining of the implant in the longitudinal direction to promote remodeling of new tissue to tendon-like tissue; and, may include a bioresorbable construction to provide transfer of additional load to new tendon-like tissue and native tendon over time. | 12-18-2014 |
20150012092 | CARBON NANOTUBES AND GRAPHENE PATCHES AND IMPLANTS FOR BIOLOGICAL TISSUE - The present invention relates to a novel composition comprising carbon nanotubes and/or graphene and a supporting material that can be used as an implant, patch or construct for the treatment, repair or replacement of biological tissue, including musculoskeletal tissue, fascia tissue, dura tissue, epidermal tissue, blood vessels and arteries, and organs. The present invention is also a method of manufacturing the novel composition, and a method of using the novel composition to treat, repair or replace biological tissue. | 01-08-2015 |
20150320543 | MEDICAL IMPLANT DELIVERY SYSTEM AND RELATED METHODS - An implant assembly for introducing and positioning implants within patients may comprise an implant device, an implant, and a sheath. The implant device may include a head, an upper beam, a lower beam, and an implant positioning component. The implant may be disposed between the upper beam and the lower beam and may include a first face engaged with the upper beam and a second face engaged with the lower beam. Additionally, the implant may be at least partially disposed around the implant positioning component. The sheath may be disposed around the implant positioning device and the implant. | 11-12-2015 |
20150342722 | IMPLANTED PASSIVE ENGINEERING MECHANISMS AND METHODS FOR THEIR USE AND MANUFACTURE - Implantable passive engineered mechanisms and a method for implanting such devices in a subject are described. The implantable passive engineered mechanism may be made of or comprise a biocompatible material and is appropriately sized for implantation in a subject. Exemplary implantable passive engineered mechanisms may be selected from a strut, a pulley, a lever, a compliant mechanism, a scissor lift, a tendon network, springs, planetary gears, rigid or soft hydraulics, a linkage system, a cam/clutch system, or combinations thereof. In some embodiments the system comprises plural inserts, such as pulleys, levers, and/or tendon networks. Plural inserts may be arranged hierarchically to distribute force differentially from an input to one or more outputs. | 12-03-2015 |
20160022874 | MEDICAL CONSTRUCTS INCLUDING TUBES AND COLLAGEN FIBERS - Medical constructs with collagen fibers and gelatin and related collagen fibers. The collagen fibers can be derived from extruded soluble dermal collagen and can include a gelatin film attached to the at least one collagen fiber. The gelatin film can include one or more minerals and has a gelatin concentration of between about 0.1% to about 40% weight per volume. | 01-28-2016 |
20160030157 | MEDICAL DEVICE DELIVERY SYSTEM AND METHOD - A tendon repair implant delivery system and methods incorporating a guide member having a temporary fixation member on or adjacent to the distal end. The point of fixation defines a target site for placement of the tendon repair implant which is subsequently affixed to the tendon. | 02-04-2016 |
20160135957 | PARTIAL JOINT RESURFACING IMPLANT, INSTRUMENTATION, AND METHOD - A partial resurfacing implant for use in repairing an articular cartilage defect site that includes a top articulating portion having a top surface that is configured with at least one radius of curvature to approximate the surface contour of the articular cartilage surrounding the defect site. The implant also includes a supporting plate that has a top surface and a bottom surface. The top surface is attached to the top articulating portion by a locking mechanism. The bottom surface of the supporting plate is constructed to facilitate the insertion of the implant into the defect site. Extending from the bottom surface of the supporting plate is at least one implant fixation portion. The at least one implant fixation portion is integrally connected to and is oriented about normal relative to the bottom surface. A method of repairing an articular cartilage defect with the partial joint resurfacing implant is also disclosed. | 05-19-2016 |
20160151165 | CORRECTION OF FIRST RAY DEFORMITY | 06-02-2016 |