02nd week of 2010 patent applcation highlights part 47 |
Patent application number | Title | Published |
20100010163 | Polyethylene Molding Composition for Producing Injection-Molded Finished Parts - The invention relates to a polyethylene molding composition which has a multimodal molecular mass distribution and comprises a low molecular weight ethylene homopolymer A, a high molecular weight ethylene copolymer B and an ultrahigh molecular weight ethylene copolymer C. The molding composition has a density at a temperature of 23° C. in the range from 0.940 to 0.957 g/cm | 2010-01-14 |
20100010164 | CURABLE RESIN COMPOSITION AND PROCESS FOR PREPARING SAME - The present invention relates to the curable resin composition, comprising (A) the reaction product of the fluorine-containing copolymer (A-1) having hydroxyl group and comprising a fluoroolefin unit and a radically polymerizable hydroxyl group-containing unsaturated monomer unit and the isocyanate group-containing unsaturated compound (A-2) having one isocyanate group and at least one radically polymerizable unsaturated group, and the reaction product is dissolved in (B) the acrylic monomer, and the present invention provides the curable resin composition being moldable even without containing an organic solvent and the preparation process thereof. | 2010-01-14 |
20100010165 | SELF-DISPERSIBLE SILICONE COPOLYMERS AND METHOD FOR THE PRODUCTION AND USE THEREOF - The invention relates to highly transparent organofunctional silicone copolymers, being self-dispersible in water without emulsifiers or protective colloid, being obtained by radically initiated solution polymerization of a) one or more ethylenically unsaturated organomonomers, and b) one or more siliconmacromeres, characterized in that c) one or more water soluble comonomeres are copolymerized in an organic solvent or solvent mixture. | 2010-01-14 |
20100010166 | SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS - Silane-terminated prepolymers which contain, on at least one silicon atom, at least one hydrolyzable aryloxy type functional group. The use of these prepolymers, containing silyl-aryloxy terminated groups, in adhesive sealant formulations increases their reactivity so enabling the use of metal-based catalysts, which are in most cases toxic and act as oxidation catalysts, to be avoided or their quantity to be reduced compared with the standard quantity used in conventional formulations, yet ensuring considerably shorter cross-linking times than those of formulations based on known silane-terminated prepolymers. | 2010-01-14 |
20100010167 | Aminde Detection Method and Materials - Compounds linked to a solid support through a divalent linker moiety are disclosed. In particular, compounds such as 1-hydroxybenzotriazole-6-carboxylic acid are directly linked to the support under mild conditions (i.e., in aqueous or organic solvents at neutral pH and at room temperature). The polymer bound 1-hydroxybenzotriazole-6-carboxylic acid can be used for the derivatization of amines as well as for single step amino group modification of proteins, peptides, and amines via acylation or sulfonylation reactions. A flow through device and method for the single step amino group modifications of proteins, peptides, and amines is disclosed. Also disclosed is a flow through device for the detection of amines in a sample. Additionally, a device and method for the detection of amines in a sample using 1-hydroxybenzotriazole-6-carboxylic acid are disclosed. In a preferred embodiment, the device is used to detect the presence of amines in a spoiled meat product. Diagnostic kits for detecting the presence of amines are also disclosed. | 2010-01-14 |
20100010168 | BETA-NUCLEATING AGENT FOR POLYPROPYLENE AND PROCESS FOR ITS PREPARATION - The present invention relates to a novel β-nucleating agent and a process for preparing same. Preferably, the β-nu-cleating agent is a water-free admixture of calcium carbonate and a calcium salt of a dibasic organic acid. | 2010-01-14 |
20100010169 | SHAPE MEMORY MATERIALS AND METHOD FOR FABRICATING THE SAME - Materials having shape memory properties and method for fabricating the same are provided. The material having shape memory properties includes a blend prepared by melt blending an amorphous polyester and a semi-crystalline polyester. The method for fabricating shape memory material includes melt blending an amorphous polyester and a semi-crystalline polyester. | 2010-01-14 |
20100010170 | PRESSURE-SENSITIVE ADHESIVES AND PROCESS FOR PREPARING THEM - The invention relates to a process for preparing a pressure-sensitive adhesive based on at least one polymer, in the course of which said at least one polymer is crosslinked, the polymer having functional groups Y and having been admixed, further, with at least one kind of functionalized particles which have at least one nonpolymeric base unit, wherein the particles having a surface modification of the base unit, the surface modification of the particles having at least one kind of functional groups Z, which can not undergo any reaction with the functional group Y and is converted into group X by thermal energy, electromagnetic radiation, particulate radiation and/or sound energy and the crosslinking of the polymer being brought about at least in part by a reaction of the functional groups X of the particles and the functional groups Y of the polymer, and further to pressure-sensitive adhesives based on at least one crosslinked polymer component, the crosslinking of the polymer component being brought about at least in part by incorporation of the functionalized particles, the particles having at least one nonpolymeric base unit and also a surface modification of this base unit, and the surface modification of the particles having at least one kind of functional groups Z which, after conversion to group X by way of thermal energy, electromagnetic radiation, particulate radiation and/or sound energy, are capable of reacting with functional groups Y present in the polymer component, and also to the use of surface-modified functionalized particles having a nonpolymeric base unit as crosslinking reagents for crosslinking polymers for preparing pressure-sensitive adhesives. | 2010-01-14 |
20100010171 | THERMOPLASTIC POLYURETHANE/BLOCK COPOLYMER COMPOSITIONS - The present invention relates to novel compositions comprising (a) anionic block copolymers of mono alkenyl arenes and isoprene, and (b) thermoplastic polyurethane elastomers. Also included are processes for the manufacturing such novel compositions and various end-uses and applications for such compositions. | 2010-01-14 |
20100010172 | IMPACT MODIFIER COMPOSITION FOR TRANSPARENT THERMOPLASTICS - The present invention relates to a toughened transparent thermoplastic composite of a transparent thermoplastic and a block copolymer having a block of a random copolymer and an elastomeric block. One preferred embodiment is a polycarbonate that is modified with a block copolymer having a methyl methacrylate (MMA) and naphthyl methacrylate or a substituted naphthyl methacrylate block and an elastomeric block. This block copolymer has excellent miscibility with polycarbonate resin, even at elevated temperature, producing transparent polycarbonate blends. The blend can provide a toughened strength polycarbonate while maintaining its excellent optical properties. | 2010-01-14 |
20100010173 | Production of Super Absorbent Polymers on a Continuous Belt Reactor - The invention relates lo a process for production of super absorbent polymers on a continuous belt reactor, wherein a continuous polymerization belt rests at least partly upon the upper surface of at least one continuous support belt. | 2010-01-14 |
20100010174 | HALF-METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS - The present invention provides polymerization catalyst compositions employing half-metallocene compounds with a heteroatom-containing ligand bound to the transition metal. Methods for making these hybrid metallocene compounds and for using such compounds in catalyst compositions for the polymerization and copolymerization of olefins are also provided. | 2010-01-14 |
20100010175 | Additives for Polyolefin Extruder Start-Up - Polymerization processes and polymers formed therefrom are described herein. The polymerization processes generally include contacting an olefin monomer with a catalyst system to form polymer within a reaction vessel, withdrawing polymer from the reaction vessel, contacting the polymer with one or more initiation additives to form a modified polymer and extruding the modified polymer. | 2010-01-14 |
20100010176 | Method for the Production of Water Absorbent Polymer Particles by Polymerizing Drops of a Monomer Solution - A process for preparing water-absorbing polymer beads by polymerizing droplets of a monomer solution in a gas phase surrounding the droplets, the initiator being added to the monomer solution from 0.5 to 60 seconds before the droplets are generated. | 2010-01-14 |
20100010177 | Method for Preparing Norbornene Monomer Composition, Norbornene Polymer Prepared Therefrom, Optical Film Comprising the Norbornene Polymer, and Method for Preparing the Norbornene Polymer - Disclosed is a method for producing a norbornene monomer composition, a norbornene polymer produced using the norbornene monomer composition, an optical film including the norbornene polymer, and a method for producing the norbornene polymer. The method includes reacting a reaction solution that contains cyclopentadiene, dicyclopentadiene, or a mixture of cyclopentadiene and dicyclopentadiene, an acetate compound, and a solvent so that a content of an exo isomer is 50 mol % or more. Variables such as a reaction temperature, a reaction time, a molar ratio between reactants, and addition of a solvent are controlled so that the exo isomer is contained in content of 50 mol % or more. Accordingly, it is possible to industrially produce an acetate norbornene addition polymer by using the acetate norbornene monomer composition containing the exo isomer in content of 50 mol % or more. | 2010-01-14 |
20100010178 | METHOD FOR THE PRODUCTION OF TELECHELIC POLYMERS - The present invention relates to the coupling of two polymer chains to give end group-functionalized polymers, the simultaneous precipitation of transition metals from polymer solutions and to the removal of halogen atoms from polymer chain ends. | 2010-01-14 |
20100010179 | DE-FOAMING SPRAY DRIED CATALYST SLURRIES - A method for preparing a spray dried catalyst and a low viscosity, low foam spray dried catalyst system for olefin polymerization are provided. In one aspect, the method includes preparing a catalyst system including one or more components selected from metallocenes, non-metallocenes, and activators, adding mineral oil to the catalyst system to form a slurry, and adding one or more liquid alkanes having three or more carbon atoms to the slurry in an amount sufficient to reduce foaming and viscosity of the slurry. In one aspect, the catalyst system includes one or more catalysts selected from metallocenes, non-metallocenes, and a combination thereof, wherein the catalyst system is spray dried. The system further includes mineral oil to form a slurry including a catalyst system, and one or more liquid alkanes having three or more carbon atoms in an amount sufficient to reduce foaming and viscosity of the slurry. | 2010-01-14 |
20100010180 | Transition Metal Complexes Supported on Activating Support - The present invention discloses an active supported catalyst system comprising:
| 2010-01-14 |
20100010181 | Catalyst Activators, Processes For Making Same, And Use Thereof In Catalysts And Polymerization Of Olefins - A composition useful for activating catalysts for olefin polymerization is provided. The composition is derived from at least; carrier containing water; organoaluminum compound; N,N-dimethylaniline and pentafluorophenol in amounts such that there are at least two equivalents of pentafluorophenol per equivalent of the N,N-dimethylaniline. | 2010-01-14 |
20100010182 | Adhesive composition, film adhesive, and method for producing the adhesive composition - An adhesive composition is disclosed which includes a polymer prepared by copolymerizing a monomer containing a polymerizable group, the polymer including a low-molecular-weight component having a molecular weight equivalent to 1% or less of the weight-average molecular weight of the polymer, the low-molecular-weight component is contained in a range of not less than 0 weight % to less than 0.3 weight % of the total weight of the polymer. This allows provision of an adhesive composition having great adhesive strength in a high-temperature environment, especially at temperatures from 140° C. to 200° C., as well as high heat resistance and favorable crack resistance. | 2010-01-14 |
20100010183 | Hyperbranched polymer and process for production thereof - There is provided a novel hyperbranched polymer in which the refractive index is precisely controlled while retaining its hyperbranched structure, and a method for producing the hyperbranched polymer. Further, there is also provided an optically and thermally stable novel hyperbranched polymer in which the desired refractive index is precisely controlled, and a method for producing the hyperbranched polymer. The hyperbranched polymer has, as a branched structure, a repeating unit structure produced from two dithiocarbamate compounds each having a vinyl structure, at the polymerization initiation site having a vinyl structure. A specific example of the hyperbranched polymer can be produced by subjecting to a living radical polymerization N,N-diethyldithiocarbamylmethylstyrene in the presence of N,N-diethyldithiocarbamylethyl methacrylate. | 2010-01-14 |
20100010184 | Process for Producing Water-Absorbing Polymer Particles - A process for producing water-absorbing polymer particles by neutralizing the monomer and cooling it by means of an indirect heat exchanger, wherein the specific cooling performance of the heat exchanger is less than 10 W/m | 2010-01-14 |
20100010185 | MODIFIED POLYDICYCLOPENTADIENES - The present invention provides novel, modified polydicyclopentadienes and methods to prepare modified polydicyclopentadienes. The modified polydicyclopentadienes prepared by the methods of the invention are useful in many applications including new and useful solid phases for chromatography. | 2010-01-14 |
20100010186 | High Strength Polyethylene Fiber - The present invention provides a high strength polyethylene fiber having an intrinsic viscosity of from about 5 dL/g to 40 dL/g, and containing carbon nanofiber modified with alkyl chains. The fiber obtained by the production method of a high strength polyethylene fiber of the present invention is industrially applicable to a wide range and greatly contributes to the industry. | 2010-01-14 |
20100010187 | GLUCOSAMINE MATERIALS - Polymers comprising glucosamine (GlcN) are used to make medical devices. Examples include polyGlcN and carrier molecules containing multiple GlcN residues. | 2010-01-14 |
20100010188 | METHOD OF POLYMERIZING SILICONE FLUID - The present invention relates to an improved method of polymerizing silicon fluids, more particularly, this method is particularly convenient for producing low viscosity silicone oils. | 2010-01-14 |
20100010189 | GAS-PHASE PROCESS FOR THE SYNTHESIS OF DIAMINOPYRIDINES FROM GLUTARONITRILES - A gas-phase, continuous process is provided for the manufacture of 2,6-diaminopyridine and related compounds from glutaronitriles, which are used industrially as compounds and as components in the synthesis of a variety of useful materials. The synthesis proceeds by means of a dehydrogenative aromatization process. | 2010-01-14 |
20100010190 | CURABLE RESIN COMPOSITION - In general, the invention provides curable resin compositions that may be used to rebuild insulation and/or to provide environmental protection for cable splices, potted articles, and the like. The curable resin compositions can be curable at room temperature. The components used to form and cure the resin compositions may be provided in two or more parts. In specific embodiments, the invention provides curable resin compositions having anhydride, polyol, epoxy, and urethane components. | 2010-01-14 |
20100010191 | Methods for Preparing Selectively-Releasable Adhesives - In one embodiment, a method for preparing a selectively releasable adhesive includes condensing a multifunctional alcohol and a multifunctional carboxylic acid to form a prepolymer and curing the prepolymer at an elevated temperature and a vacuum to produce a cured polymer. | 2010-01-14 |
20100010192 | PROCESS FOR PRODUCING RESIN FOR OPTICAL MATERIAL - Disclosed is a process for producing effectively a high performance optical material (e.g. a lens) made of a polyurethane resin, which is transparent and colorless without a strain. In this process, the optical material is produced without causing striation or clouding by polymerizing a polymerizable composition comprising a polythiol compound and a polyiso(thio)cyanate compound, and characterized in that a water content in the composition is 10 to 300 ppm. | 2010-01-14 |
20100010193 | Immunogenic complexes and methods relating thereto - The present invention relates generally to an immunogenic complex comprising a charged organic carrier and a charged antigen and, more particularly, a negatively charged organic carrier and a positively charged antigen. The complexes of the present invention are useful, inter alia, as therapeutic and/or prophylactic agents for facilitating the induction of a cytotoxic T-lymphocyte response to an antigen. | 2010-01-14 |
20100010194 | Method for Preparing a Polymer Conjugate - Provided herein is a straightforward and efficient method for covalently attaching a polyethylene glycol polymer to an active agent. | 2010-01-14 |
20100010195 | Novel tumor necrosis factor receptor homolog and nucleic acids encoding the same - The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. | 2010-01-14 |
20100010196 | COMPOSITIONS AND METHODS FOR NON-TARGETED ACTIVATION OF ENDOGENOUS GENES - The present invention is directed generally to activating gene expression or causing over-expression of a gene by recombination methods in situ. The invention also is directed generally to methods for expressing an endogenous gene in a cell at levels higher than those normally found in the cell. In one embodiment of the invention, expression of an endogenous gene is activated or increased following integration into the cell, by non-homologous or illegitimate recombination, of a regulatory sequence that activates expression of the gene. In another embodiment, the expression of the endogenous gene may be further increased by co-integration of one or more amplifiable markers, and selecting for increased copies of the one or more amplifiable markers located on the integrated vector. In another embodiment, the invention is directed to activation of endogenous genes by nontargeted integration of specialized activation vectors, which are provided by the invention, into the genome of a host cell. The invention also provides methods for the identification, activation, isolation, and/or expression of genes undiscoverable by current methods since no target sequence is necessary for integration. The invention also provides methods for isolation of nucleic acid molecules (particularly cDNA molecules) encoding a variety of proteins, including transmembrane proteins, and for isolation of cells expressing such transmembrane proteins which may be heterologous transmembrane proteins. The invention also is directed to isolated genes, gene products, nucleic acid molecules, to compositions comprising such genes, gene products and nucleic acid molecules, and to vectors and host cells comprising such genes and nucleic acid molecules, that may be used in a variety of therapeutic and diagnostic applications. Thus, by the present invention, endogenous genes, including those associated with human disease and development, may be activated and isolated without prior knowledge of the sequence, structure, function, or expression profile of the genes. | 2010-01-14 |
20100010197 | METHOD AND SYSTEM FOR CORN FRACTIONATION - Methods and apparatus for processing corn into one or more corn products. Oil is extracted from corn or corn products or by-products with a solvent. The corn-solvent mixture is separated into streams, one of which preferably includes an extract containing at least oil and solvent, and another containing de-oiled corn solids and adsorbed solvent. Zein is separated from the de-oiled corn solids. Solvent is then separated, and the de-oiled, de-zeined, desolventized corn solids are processed to provide one or more corn products. | 2010-01-14 |
20100010198 | Soluble Canola Protein Isolate Production ("Nutratein") - Canola protein isolates are provided which contain both albumin and globulin protein fractions that are soluble and parent in an acidic aqueous environment. The canola protein isolates are completely soluble in water at low pH, low in phytic acid and useful in products for human consumption, pet foods and aquaculture. | 2010-01-14 |
20100010199 | MAKING INFLUENZA VIRUS VACCINES WITHOUT USING EGGS - Currently, the steps performed prior to release of influenza strains to vaccine manufacturers involve passaging influenza virus through eggs. The invention aims to provide procedures useful in manufacturing influenza vaccines, in which the use of eggs is reduced, and preferably is avoided altogether. For instance, rather than use chicken eggs for influenza vaccine isolation, MDCK cells (Madin Darby canine kidney cells) may be used e.g. growing in suspension, growing in a serum-free medium, growing in a protein-free medium, being non-tumorigenic, grown in the absence of an overlay medium, etc. | 2010-01-14 |
20100010200 | INTERLEUKIN-18 BINDING PROTEINS, THEIR PREPARATION AND USE - Interleukin-18 binding proteins which are capable of binding IL-18 and/or modulating and/or blocking IL-18 activity are provided. Methods for their isolation and recombinant production, DNAs encoding them, DNA vectors expressing them, vectors useful for their expression in humans and other mammals, antibodies against them are also provided. | 2010-01-14 |
20100010201 | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods - The present invention relates in general to metalloproteinase inhibitors and to polynucleotides encoding such inhibitors. In particular, the invention relates to novel mammalian inhibitors of metalloproteinase, which are designated as type three or TIMP-3, to fragments, derivatives, and analogs thereof, and to polynucleotides encoding the same. Novel methods of producing such compositions and novel methods of using such compositions are also provided. | 2010-01-14 |
20100010202 | Human antibodies derived from immunized xenomice - Fully human antibodies against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof. | 2010-01-14 |
20100010203 | ANTI-HYDROXYLASE ANTIBODIES AND USES THEREOF - Antibodies, or antigen-binding portions thereof, to aspartyl (asparaginyl) β-hydroxylase are provided. The anti-aspartyl (asparaginyl) β-hydroxylase antibodies, or antigen-binding portions thereof, can modulate activity of aspartyl (asparaginyl) β-hydroxylase. | 2010-01-14 |
20100010204 | METHOD OF PREPARING COMPLEX-AZO PIGMENT AND COMPLEX-AZO PIGMENT THEREOF - A method of preparing a complex-azo pigment having plural pigment components including at least an azo pigment represented by the following formula (a) | 2010-01-14 |
20100010205 | NAPHTHALENE 2-CARBOXYLATE DERIVATIVE USEFUL FOR SYNTHESIZING GEMCITABINE AND A METHOD FOR PREPARING THE SAME - Disclosed herein are novel naphthalene-2-carboxylate derivatives of Formula (I), which are useful for the synthesis of gemcitabine, as well as a preparation method. The novel derivatives have naphthalene-2-carboxlate as the hydroxy protecting group of 2-deoxy-2,2-difluoro-pentofuranose-1-ulose. (I) wherein R1 and R2 are each independently hydrogen, methyl, chloro, fluoro, bromo, iodo, methoxy, ethoxy or nitro. | 2010-01-14 |
20100010206 | siRNA Targeting Hypoxia-Inducible Factor 1 - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed. | 2010-01-14 |
20100010207 | RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES - Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a | 2010-01-14 |
20100010208 | PURIFICATION OF A TRIPLE HELIX FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE - Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix. | 2010-01-14 |
20100010209 | METHOD AND APPARATUS FOR COMBINATORIAL CHEMISTRY - A method and apparatus are provided for performing light-directed reactions in spatially addressable channels within a plurality of channels. One aspect of the invention employs photoactivatable reagents in solutions disposed into spatially addressable flow streams to control the parallel synthesis of molecules immobilized within the channels. The reagents may be photoactivated within a subset of channels at the site of immobilized substrate molecules or at a light-addressable site upstream from the substrate molecules. The method and apparatus of the invention find particularly utility in the synthesis of biopolymer arrays, e.g., oligonucleotides, peptides and carbohydrates, and in the combinatorial synthesis of small molecule arrays for drug discovery. | 2010-01-14 |
20100010210 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 2010-01-14 |
20100010211 | Vaccine - The invention relates to a vaccine for the treatment of disease caused by | 2010-01-14 |
20100010212 | Processes for the preparation of (3R,4S)-4-((4-benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophen- yl)-3-hydroxypropyl)-2-azetidinone, an intermediate for the synthesis of ezetimibe - The invention encompasses (3R,4S)-4-((4-benzyloxy)phenyl)-1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-oxopropyl)-2-azetidinone (Compound 2a) having an enantiomeric purity of at least about 97.5%. The invention also encompasses Compound 2a having a chemical purity of at least about 97%. The invention further encompasses processes for preparing Compound 2a from Compound 1 having the following formula: | 2010-01-14 |
20100010213 | PROCESS FOR THE CRYSTALLISATION OF CEFADROXIL - The present invention relates to a process for the preparation of cefadroxil in crystal form, comprising a) adding an aqueous solution of cefadroxil to a crystallisation vessel and a titrant to keep a pH in the crystallisation vessel of between 7 to 9; and b) lowering the pH in the crystallisation vessel to a value of between 5 and 6.5 to obtain a suspension of the β-lactam compound in crystal form. The invention further relates to cefadroxil in crystal form obtainable by the process according to the present invention. The invention also relates to cefadroxil in crystal form with a CIE b value of below 12 when stored at a temperature of 25° C. for at least 1 month. | 2010-01-14 |
20100010214 | LYOPHILIZED PREPARATION OF 1-METHYLCARBAPENEM - A lyophilized preparation comprising (1R,5S,6S)-6-[(1R)-1-hydroxyethyl]-1-methyl-2-[(2S,4S)-2-[(3S)-3-(2-guanidinoacetylamino)pyrrolidin-1-ylcarbonyl]-1-methylpyrrolidin-4-ylthio]-1-carbapen-2-em-3-carboxylic acid or a pharmacologically acceptable salt thereof as a carbapenem compound, which has a 1-alkylpyrrolidine structure and possesses a superior antimicrobial activity, and sodium chloride. | 2010-01-14 |
20100010215 | Introverted CB[N] Compounds - Inverted cucurbituril compounds having at least one pair of hydrogen atoms protruding into an internal molecular cavity thereof. | 2010-01-14 |
20100010216 | 2-FLUORINATED ACYL-3-AMINOACRYLONITRILE DERIVATIVE AND METHOD FOR PRODUCING THE SAME - The invention provides a 2-fluorinated acyl-3-aminoacrylonitrile derivative, and a method for producing the same. A desired 2-fluorinated acyl-3-aminoacrylonitrile derivative represented by the following Formula (3) is obtained by reacting a fluorinated acyl derivative with an aminoacrylonitrile derivative. In Formula (3), Rf represents an alkyl group having 1 to 6 carbon atoms which is substituted with at least one fluorine atom, R | 2010-01-14 |
20100010217 | METHODS FOR THE PREPARATION OF IMIDAZOLE-CONTAINING COMPOUNDS - The present invention generally relates to methods for the preparation of compounds that contain imidazole moieties. In some embodiments, the methods include the reaction of a diamine with a dichloroimmonium compound to produce the imidazole moiety. In some embodiments, the methods are employed to prepare compounds having the Formulas II, II or III below: I II III wherein the constituent variables are as described herein. | 2010-01-14 |
20100010218 | SYNTHESIS OF PALIPERIDONE - A compound of formula (6) or an acid addition salt thereof | 2010-01-14 |
20100010219 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND - Provided is a method capable of efficiently producing a compound having a superior HSD1 inhibitory action and a compound useful as a synthetic intermediate therefor, with superior achievability of asymmetric synthesis (i.e., superior selectivity), superior yield, superior safety and superior industrial workability at a low cost. | 2010-01-14 |
20100010220 | Process for Preparing Amidrazones - The present invention relates to a novel process for preparing amidrazones of the formula (I) wherein R, R | 2010-01-14 |
20100010221 | PROCESSES FOR PURIFYING VARENICLINE L-TARTRATE SALT AND PREPARING CRYSTALLINE FORMS OF VARENICLINE L-TARTRATE SALT - Processes for purifying Varenicline base or the L-tartrate salt thereof and for preparing Varenicline L-tartrate crystalline forms A and B are provided. | 2010-01-14 |
20100010222 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DISEASES ASSOCIATED WITH DECREASE IN BONE MASS COMPRISING EP4 AGONIST AS ACTIVE INGREDIENT - A pharmaceutical composition for topical administration for prevention and/or treatment of diseases associated with decrease in bone mass comprising an EP | 2010-01-14 |
20100010223 | Pyrazine derivatives, Methods of use, and methods for preparing same - The present invention relates to methods for producing N,N′-alkylated diaminopyrazines. | 2010-01-14 |
20100010224 | PROCESS FOR PRODUCTION OF HETEROARYL-TYPE BORON COMPOUNDS WITH IRIDIUM CATALYST - The present invention provides an economically and industrially superior simple process that enables the selective production of an aromatic heterocyclic monoboron compound and aromatic heterocyclic diboron compound at a satisfactory yield and in a desired ratio by reacting an aromatic heterocyclic compound and a boron compound in a single step under mild conditions while changing only the charged ratios of the raw materials. | 2010-01-14 |
20100010225 | ISOQUINUCLIDINE DERIVATIVE AND METHOD FOR MANUFACTURING 1-CYCLOHEXENE-1-CARBOXYLIC ACID DERIVATIVE USING THE SAME - The present invention provides an isoquinuclidine derivative which can be used to easily synthesize oseltamivir or an analog thereof. In particular, the present invention provides an isoquinuclidine derivative represented by the following formula (1) or an enantiomer thereof: | 2010-01-14 |
20100010226 | TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE - The present invention relates to the compound of formula 7*acetate (see below), a process for its preparation, and its use | 2010-01-14 |
20100010227 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES - The present invention discloses a process for preparing the piperidine derivative compound 4-[4-[4-hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylphenylacetic acid of formula | 2010-01-14 |
20100010228 | PROCESS FOR THE ASYMMETRIC REDUCTION OF 3-BENZOYLPIPERIDINES - Disclosed is a process for the asymmetric preparation of a phenyl(3-piperidinyl)methanol represented by Formula (I): | 2010-01-14 |
20100010229 | FEXOFENADINE POLYMORPH - The present invention provides a novel fexofenadine hydrochloride polymorph. The polymorph is particularly useful as a medicament for use as an antihistamine, antiallergy agent or bronchodilator. | 2010-01-14 |
20100010230 | Method for the purification of lansoprazole - The present invention relates to an improved process for the preparation of Lansoprazole of formula (I). More particularly, the present invention relates to a method for the purification of crude Lansoprazole in a solvent in presence of an alkali salt of an organic acid or in presence of an organic base such as piperidine or imidazole. | 2010-01-14 |
20100010231 | METAL COMPLEX, LUMINESCENT DEVICE AND DISPLAY APPARATUS - There is provided a novel luminescent metal complex. A metal complex having a composition of [(Pt | 2010-01-14 |
20100010232 | Aryl derivatives of curcumin, demethoxycurcumin, bisdemethoxycurcumin or curcuminisoxazolide and their use as animal feed additives - The present invention relates to the use of acyl derivatives of curcumin, desmethoxy curcumin and bisdesmethoxy curcumin and of curcuminisoxazolide as components of animal feed or feed additives for the improvement of animal performance and the new acyl derivatives per se as well as the corresponding animal feed or feed additives containing them. | 2010-01-14 |
20100010233 | PROCESS FOR PREPARING IMIDAZOLIDIN-2,4-DIONE COMPOUND AND METHOD FOR ACQUIRING SOLID STATE 4,5-DIHYDROXY-2-IMIDAZOLIDINONE COMPOUND - An object of the present invention is to provide an industrially suitable process for preparing an imidazolidin-2,4-dione compound which is safe, simple and easy to prepare the imidazolidin-2,4-dione compound with high yield, which is a useful compound, for example, as a material for decomposing a harmful halogenated aromatic hydrocarbon compound such as dioxin, etc., an electroless silver plating solution for electronic parts, or a diazo copying material, etc. This object can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises subjecting a 4,5-dihydroxy-2-imidazolidinone compound, (1) to dehydration reaction in the presence of an acid catalyst(s); or (2) to reaction at 100 to 300° C. Or, it can be solved by a process for preparing an imidazolidin-2,4-dione compound which comprises reacting a mixed solution of a urea compound, glyoxal, and a base at 20 to 300° C. | 2010-01-14 |
20100010234 | PROCESS FOR MANUFACTURING A GLUTAMIC ACID DERIVATIVE AND A PYROGLUTAMIC ACID DERIVATIVE AND A NOVEL INTERMEDIATE IN THE MANUFACTURE THEREOF - Glutamic acid derivatives, in particular monatin, may be conveniently prepared by alkylating a 4-protected hydroxyl pyroglutamic acid derivative with an alkylating agent to prepare a 4-protected hydroxyl-4-alkylglutamic acid derivative, followed by the steps of hydrolysis and deprotection. The 4-protected hydroxyl pyroglutamic acid derivative is easy to produce from hydroxyproline. The 4-protected hydroxyl pyroglutamic acid derivative is particularly suitable for use in the efficient manufacture of monatin of high optical purity, since it can be alkylated selectively at the 4-position and stereoselectively and after its alkylation, it can easily be converted to a glutamic acid derivative. | 2010-01-14 |
20100010235 | Method of using rhodium quinonoid catalysts - In accordance with aspects of the invention methods of using rhodium hydroquinone catalysts for the conjugate addition of boronic acids are disclosed. | 2010-01-14 |
20100010236 | CATALYTIC PROCESS FOR PREPARING (METH)ACRYLIC ESTERS OF N-HYDROXYALKYLATED LACTAMS - A process for preparing (meth)acrylic esters (F) of N-hydroxyalkylated lactams, in which cyclic N-hydroxyalkylated lactams (L) | 2010-01-14 |
20100010237 | FUSED THIOPHENES, METHODS FOR MAKING FUSED THIOPHENES, AND USES THEREOF - Described herein are compositions including heterocyclic organic compounds such as fused thiophene compounds, methods for making them, and uses thereof | 2010-01-14 |
20100010238 | PROCESS FOR PRODUCING A RINGLIKE OXIDIC SHAPED BODY - A process for producing a ringlike oxidic shaped body by mechanically compacting a pulverulent aggregate introduced into the fill chamber of a die, wherein the outer face of the resulting compact corresponds to that of a frustocone. | 2010-01-14 |
20100010239 | Process for the Production of Prostaglandins and Prostaglandin Analogs - The present invention relates to an improved process for the production of prostaglandins and prostaglandin analogs. In particular, this invention relates to the production of prostaglandins of the PGF | 2010-01-14 |
20100010240 | SYNTHESIS OF POLYCYCLIC PROCYANIDINS - The invention provides compounds that are A-type procyanidins. The compounds can be prepared by reacting flavylium salts with catechins or analogs thereof, for example, under anhydrous conditions in alcohol. | 2010-01-14 |
20100010241 | Cosmetics - The present invention provides a cosmetic having equal to or a higher antioxidant activity and moisture retaining property than the above-described conventional vitamin E derivatives. The cosmetic also has an excellent emulsifying ability and solubilizing ability and remarkably reduces a sticky feeling on the skin (in particular, the sticky feeling during drying after the application on the skin). That is, the cosmetic of the present invention containing a vitamin E derivative represented by the following formula (I) or a salt thereof. | 2010-01-14 |
20100010242 | Process for Preparing beta-Amino-alpha-Hydroxycarboxamides - The present invention is directed to a process for preparing β-amino-α-hydroxycarboxamides. The process works with epoxycarboxamides of the formula 2 | 2010-01-14 |
20100010243 | EPOXIDATION CATALYST AND PROCESS - Disclosed herein is a catalytic method of converting alkenes to epoxides. This method generally includes reacting alkenes with oxygen in the presence of a specific silver catalyst under conditions suitable to produce a yield of the epoxides. The specific silver catalyst is a silver nanocrystal having a plurality of surface planes, a substantial portion of which is defined by Miller indices of (100). The reaction is performed by charging a suitable reactor with this silver catalyst and then feeding the reactants to the reactor under conditions to carry out the reaction. The reaction may be performed in batch, or as a continuous process that employs a recycle of any unreacted alkenes. The specific silver catalyst has unexpectedly high selectivity for epoxide products. Consequently, this general method (and its various embodiments) will result in extraordinarily high epoxide yields heretofore unattainable. | 2010-01-14 |
20100010244 | Method For Producing Fatty Acid Alkanol Amides - The invention relates to a method for producing fatty acid alkanol amides by reacting at least one amine that contains at least one primary or secondary amino group and at least one hydroxyl group with at least one fatty acid to form an ammonium salt, said ammonium salt being subsequently converted into the alkanol amide by means of microwave radiation. | 2010-01-14 |
20100010245 | RESINS OF NATURAL ORIGIN DERIVED FROM VEGETABLE OIL AND FROM HYDROXY ACIDS - The present invention relates to an organic resin derived from a naturally occurring oil or fat comprising monoglycerides and/or diglycerides, esterified with a poly(hydroxy acid) having the following formula: | 2010-01-14 |
20100010246 | METHODS AND CATALYSTS FOR MAKING BIODIESEL FROM THE TRANSESTERIFICATION AND ESTERIFICATION OF UNREFINED OILS - A method of forming a biodiesel product and a heterogeneous catalyst system used to form said product that has a high tolerance for the presence of water and free fatty acids (FFA) in the oil feedstock is disclosed. This catalyst system may simultaneously catalyze both the esterification of FAA and the transesterification of triglycerides present in the oil feedstock. The catalyst system according to one aspect of the present disclosure represents a class of zinc and lanthanum oxide heterogeneous catalysts that include different ratios of zinc oxide to lanthanum oxides (Zn:La ratio) ranging from about 10:0 to 0:10. The Zn:La ratio in the catalyst is believed to have an effect on the number and reactivity of Lewis acid and base sites, as well as the transesterification of glycerides, the esterification of fatty acids, and the hydrolysis of glycerides and biodiesel. | 2010-01-14 |
20100010247 | NOVEL METHOD FOR PRODUCING BIODIESEL USING AN IMMOBILISED CATALYST - A method produces a fatty acid alkylester by transesterification of a fat or oil and an alcohol. The reaction is catalysed by a heterogeneous catalyst immobilised in a tubular reactor at a temperature between 260 and 420° C. and at a pressure higher than 5 bar. A mixture of the fat or oil and the alcohol is led in a continuous flow through the tubular reactor. The catalyst is preferably a metal oxide or a metal carbonate including an alkaline earth metal. The reaction takes place at reduced residence times and contact times compared to the prior art. | 2010-01-14 |
20100010248 | IMIDE COMPLEX, METHOD FOR PRODUCING THE SAME, METAL-CONTAINING THIN FILM AND METHOD FOR PRODUCING THE SAME - Objects of the present invention are to provide a novel niobium or tantalum complex having good vapor pressure and becoming a raw material for producing a niobium- or tantalum-containing thin film by a method such as CVD method, ALD method or the like, a method for producing the same, a metal-containing thin film using the same, and a method for producing the same. The present invention relates to producing an imide complex represented by the general formula (1) by, for example, the reaction between M | 2010-01-14 |
20100010249 | LITHIUM SALT - The principal object of the invention is to provide a lithium salt having excellent ion conductivity. The invention solves the problem by providing a lithium salt having a structure represented by the general formula (1): in which “M” represents B, Si, Ge, P, As or Sb; “X” represents the valence of “M”; “R | 2010-01-14 |
20100010250 | METHODS FOR PREPARING 2-METHOXYISOBUTYLISONITRILE AND TETRAKIS(2-METHOXYISOBUTYLISONITRILE)COPPER(I) TETRAFLUOROBORATE - The present invention relates to new synthetic methods for preparing 2-methoxyisobutylisonitrile and metal isonitrile complexes, such as tetrakis(2-methoxyisobutylisonitrile)copper(I) tetrafluoroborate, which are used in the preparation of technetium ( | 2010-01-14 |
20100010251 | PREPARATION OF ALKOXYSULFATES - A process for the preparation of alkoxysulfates from organic compounds containing one or more nucleophilic groups by reacting said organic compound, in a water-miscible solvent selected from the group consisting of sulfur-containing solvents such as dimethylsulfoxide (DMSO) or sulfolane, or polar solvents such as tetrahydrofuran (THF), dimethylformamide (DMF), dimethylacetamide (DMA) and hexamethylphosphoric triamide (HMPT), with an alkylene sulfate, in a non-water-miscible solvent selected from the group consisting of chlorinated solvents such as methylene chloride, chloroform, carbon tetrachloride, trichloroethane or chlorinated aromatics, such as chlorobenzene or dichlorobenzene, and non-chlorinated aromatics, such as toluene or xylenes, in the presence of a base selected from the group consisting of hydroxides, carbonates and hydrogen carbonates of alkali metals or alkaline earth metals. | 2010-01-14 |
20100010252 | PROCESS FOR PREPARING DIARYL CARBONATES FROM DIALKYL CARBONATES - The invention provides a process for preparing diaryl carbonates from dialkyl carbonates and aromatic hydroxyl compounds using at least two reaction columns, a process section for recovering the dialkyl carbonate used in the reaction and for removing the alcohol of reaction, one or more process steps for removing the by-products obtained in the process which have a boiling point between that of the dialkyl carbonate and that of the alkyl aryl carbonate formed during the preparation of the diaryl carbonate, and a process step for further purification of the diaryl carbonate obtained from the reaction columns. | 2010-01-14 |
20100010253 | RECOVERY OF BIS(DIARYLPHENOL) LIGANDS DURING THE PRODUCTION OF ISOPULEGOL - The present invention relates to a method of working up an aluminium-containing reaction product from the production of isopulegol by cyclization of citronellal in the presence of complex compounds, comprising at least one ligand of the formula (I), | 2010-01-14 |
20100010254 | METHOD OF PRODUCING OPTICALLY ACTIVE ALPHA-AMINO ACID BENZYL ESTERS - A method of is provided for producing optically active α-amino acid benzyl esters. The method includes reacting an optically active α-amino acid and benzyl alcohols in the presence of an acid, wherein the reaction is carried out under reduced pressure without substantially using a solvent, while distilling off water generated by the progress of the reaction. | 2010-01-14 |
20100010255 | NOVEL ALPHA-FLUOROMETHOXYCARBOXYLIC ESTER, PROCESS FOR PRODUCING THE ALPHA-FLUOROMETHOXYCARBOXYLIC ESTER, AND PROCESS FOR PRODUCING SEVOFLURANE - The present invention provides a novel α-fluoromethoxycarboxylic ester represented by Formula (1): (CF | 2010-01-14 |
20100010256 | PROCESSES FOR HYDROGEN CHLORIDE OXIDATION USING OXYGEN - Processes which include: (a) providing a gas phase comprising hydrogen chloride; (b) oxidizing the hydrogen chloride in a reactor to form a product gas comprising chlorine, unreacted hydrogen chloride and water, the reactor having structural parts with inner surfaces that are contacted during oxidation by one or both of the gas phase and the product gas; (c) cooling the process gas; (d) separating the unreacted hydrogen chloride and water from the product gas; (e) drying the product gas; and (f) separating the chlorine from the product gas; wherein the inner surfaces of the reactor structural parts that are contacted during oxidation by one or both of the gas phase and the product gas are comprised of a nickel material having a nickel content of at least 60 wt. %, are described. | 2010-01-14 |
20100010257 | SEPARATION OF AMMONIUM CHLORIDE FROM THE GAS PHASE OF AN ISOCYANATE PRODUCTION PROCESS - Isocyanates are produced in the gas phase and by-products such as ammonium halides are selectively separated from the gas phase by desublimation. | 2010-01-14 |
20100010258 | PROCESS FOR MAKING 1-HYDROXYALKYLIDENE-1,1-BIPHOSPHONIC ACIDS - Synthesis of biphosphonate compounds can be advantageously carried out in a solvent/diluent comprising a compound of formula (3) | 2010-01-14 |
20100010259 | Process for producing anhydrous peroxydisulfuric, acid using sulfur trioxide recovered from a waste comprising sulfuric acid - A process for producing peroxydisulfuric acid from a waste comprising substantially sulfuric acid, whereby the sulfuric acid is separated into sulfur trioxide and substantially water which is removed as a waste. The recovered sulfur trioxide is reacted with hydrogen peroxide to produce peroxydisulfuric acid which is fed to a methane-sulfonation process resulting in formation of sulfuric acid radicals. The sulfuric acid radicals react with methane producing methane radicals resulting in formation of sulfuric acid. The sulfuric acid from the methane-sulfonation process is recovered, reprocessed, and the process is repeated. | 2010-01-14 |
20100010260 | PROCESS FOR PRODUCING ACRYLIC ACID - The present invention provides a process for producing acrylic acid from glycerin with a catalyst having a prolonged life. In the process for producing acrylic acid from glycerin, a molar ratio of oxygen to glycerin in a raw material gas is set to be not lower than 0.8 and not higher than 20. | 2010-01-14 |
20100010261 | PRODUCTION OF AMINES - A process for the hydrogenation of carboxylic acids and/or derivatives, particularly amides, is described. The process includes reacting an acid or derivative such as an amide with a source of hydrogen in the presence of a catalyst system. The catalyst system obtainable by combining: (a) a source of ruthenium, and (b) a phosphine compound of general Formula I: (Formula I). The hydrogenation reaction is carried out in the presence of a low concentration of water or at low pressure or in the presence of a source of ammonia or the hydrogenation reaction is carried out in the absence of water or a combination of these factors is utilised. The invention also relates to the use of ammonia in the production of primary amines by hydrogenation of carboxylic acids and/or derivatives thereof or a process for the production of primary amines generally. | 2010-01-14 |
20100010262 | COMPOSITIONS AND METHOD FOR MAKING THEREOF - A composition has a structure as shown in formula I: | 2010-01-14 |