02nd week of 2021 patent applcation highlights part 38 |
Patent application number | Title | Published |
20210010978 | VIBRO-ACOUSTIC DELIVERY SYSTEM - A vibro-acoustic assembly and related systems and methods for applying a wide range of audio frequencies in one or multiple channels to living beings for wellbeing. The assembly is ergonomic, compact, portable and configured to address physically any area of a user's body while being flexible and easy to use to deliver a wide degree of frequencies/identified targeted programs from a source audio device, such as a smart phone application via wireless transmission. | 2021-01-14 |
20210010979 | INLINE CYCLE FUSE - A system and method of predicting impending failure of a pressure vessel include a pressure vessel, a fluid source, a line coupled to the pressure vessel and to the fluid source, an apparatus, a sensor and a controller. The apparatus includes a conduit and a containment structure. The containment structure includes a cavity separated from an interior of the conduit by a portion of a conduit wall of the conduit. The sensor is configured to determine a value of a physical property in the cavity. The controller is in signal communication with the sensor and configured to detect a change in the value. The method includes determining a first value of a physical property in the cavity, experiencing a failure of the conduit wall, determining a second value of the physical property in the cavity, and detecting a difference between the first and second values. | 2021-01-14 |
20210010980 | SYSTEM IDENTIFICATION DEVICE, SYSTEM IDENTIFICATION METHOD, AND RECORDING MEDIUM - A system identification device | 2021-01-14 |
20210010981 | CHROMATOGRAPH DATA PROCESSOR AND AUTOMATIC SAMPLE INJECTOR - First analysis information including at least one of a sample analysis condition, a sample preparation condition and a kind of sample is assigned to at least one kind of jig, and the jig is arrangeable to correspond to any of a plurality of sample holders. Holding information representing whether a sample is held by each sample holder and jig information for identifying the kind of jig are acquired by a first information acquirer from an automatic sample injector. The first analysis information in regard to a corresponding sample holder is specified by a first analysis information specifier based on jig information. A batch file for controlling a sequence of analysis or preparation in regard to a sample held by a sample holder corresponding to a jig is created by a batch file creator with use of the holding information and the first analysis information. | 2021-01-14 |
20210010982 | ANALYZER - An analyzer capable of suppressing the generation of noise in a current detection circuit is provided. On a board | 2021-01-14 |
20210010983 | MICROCHANNEL PHOTOIONIZATION DETECTOR - A microfluidic photoionization detector (PID) may include a substrate and an electrically conductive layer formed on the substrate. The electrically conductive layer may include a microchannel, and a first electrode region and a second electrode region separated from each other by the microchannel, an ohmic contact layer formed on top of the first electrode region and the second electrode region, and a light source formed on the ohmic contact layer for emitting light toward the microchannel. | 2021-01-14 |
20210010984 | METHOD FOR DETERMINING WEIGHT-AVERAGE MOLECULAR WEIGHT AND CONTENT OF SOLUBLE SALT OF ACIDIC CARBOHYDRATES - The invention belongs to the technical field of natural medicinal chemistry and quality control thereof, and relates to a method for determining the weight average molecular weight and the purity of a soluble salt of an acidic saccharide. The method comprises using metal ion content in the soluble salt of an acidic saccharide to correct the weight average molecular weight and the content of the of acid saccharide obtained by the combined use of the molecular sieve chromatography and a multi-angle laser scattering detector SEC-MALS. The method of the present invention can be used to more quickly and accurately determine the weight average molecular weight and content of acidic saccharide soluble salts. | 2021-01-14 |
20210010985 | METHOD FOR DETERMINING THE ANTIOXIDANT CAPACITY OF A BIOLOGICAL SAMPLE AND RELATED KIT - A method for determining the antioxidant power of a sample of a biological fluid or a food is provided. The method involves contacting the sample to be tested with an aqueous solution of palladium nanoparticles, an oxidizing agent, and a chromogenic peroxidase substrate, and detecting the colour of the final solution thus obtained. The colour intensity of the solution is proportional to the antioxidant power of the sample. A kit for carrying out the method is also provided. | 2021-01-14 |
20210010986 | PAPERLESS RECORDING PASTEURIZATION CONTROL SYSTEM - A pasteurization system includes at least a temperature sensor, a control signal generator, and a processor structured to record a stream of temperatures as well as their associated times of recordation, and to cause the control signal generator to generate a control signal based on the recorded temperatures. | 2021-01-14 |
20210010987 | Detection of Non-XR/MD Detectable Foreign Objects in Meat - Disclosed is an inspection system having a background positioned adjacent an inspection zone; and an image capturing device configured to receive background electromagnetic radiation (EMR) from the background and from the inspection zone, the inspection zone being configured and arranged to receive material for transport into the inspection zone; wherein the background has a background property defined by a background emission, a background absorbance, and a background reflectance, the background property being matched in EMR to a material EMR of material to be transported into the inspection zone, the material having a material property defined by a material emission, a material absorbance, and a material reflectance; and wherein the image capturing device is configured to detect a foreign object within material when transported into the inspection zone by deducting the background EMR from the material EMR. | 2021-01-14 |
20210010988 | SYSTEMS AND METHODS FOR CHARACTERIZING SURFACTANT PROTEIN D (SP-D) OLIGOMERS - Some embodiments of the methods and compositions provided herein include identifying and/or quantifying oligomeric species of surfactant protein-D (SP-D). Some embodiments include performing an asymmetric flow field-flow fractionation with multi-angle laser light scattering (AF4-MALLS) analysis on the SP-D. | 2021-01-14 |
20210010989 | MULTI PARAMETER SWIMMING POOL FLUID ANALYSIS AND REGULATING METHOD AND DEVICE - There may be provided a system comprising a spectroscopic device; wherein the spectroscopic device is configured to analyze a fluid of a pool. | 2021-01-14 |
20210010990 | SYSTEM AND METHOD FOR DETECTION AND DISPOSAL OF MICROORGANISMS AND DETECTION MODULE DISPOSED IN A WATER FLOW POINT - A system and method for the detection and elimination of microorganisms in a water flow. The method comprises the steps of: arranging at least one light emission element at a water flow point, arranging of at least one light capture element at the water flow point, detecting the presence of the microorganism through the first light emission event and eliminating the microorganism through the realization of a second light emission event. It also describes a detection module which can be positioned at a water flow point. | 2021-01-14 |
20210010991 | Sensor cleaning and calibration devices and systems - An electrode cleaning and calibration system generally comprises a sensor holder assembly machined from a block of solid acrylic or similar plastic material, which can accommodate a variety of types and sizes of sensors for use in monitoring and measurement of water processing and treatment processes. Examples of sensors suitable for use in the system include pH sensors, dissolved oxygen sensors, chlorine sensors, ozone sensors, total suspended solid sensors, mixed liquor suspended solid sensors, ammonia sensors, monochloramine sensors, and ultraviolent transmittance sensors. | 2021-01-14 |
20210010992 | SYSTEMS AND METHODS FOR AUTOMATED WETSTOCK MANAGEMENT - An automated wetstock management system can include a plurality of sensors disposed in a fuel storage facility, the plurality of sensors configured to sense fuel data characterizing one or more aspects of the fuel storage facility, and a wetstock management server communicatively coupled to the plurality of sensors. The wetstock management server can process the fuel data to detect whether the fuel data satisfies an exception indicative of an operational issue of the fuel storage facility based on one or more predefined rules or models stored in the wetstock management server. In some embodiments, the wetstock management server can generate a workflow for assisting a user of the fuel storage facility to resolve the operational issue. In some embodiments, the wetstock management server can assign a risk category to the exception and electronically transmit an alert characterizing the operational issue to the user. | 2021-01-14 |
20210010993 | USE OF SOIL AND OTHER ENVIRONMENTAL DATA TO RECOMMEND CUSTOMIZED AGRONOMIC PROGRAMS - The subject invention provides systems and methods for classifying a microbiome at a geographic site where agricultural activity is, or will be, conducted in order to improve and/or promote agricultural productivity at the site. The subject invention utilizes a large sample set of diverse DNA sequencing input data collected from soil, plant, water and/or air samples, as well as environmental information, to determine relationships between environmental factors and the identities, quantities and distributions of microbial species, taxonomies, and/or groupings thereof, at a chosen site. Machine learning and/or artificial intelligence classifier tools use this information to generate various output data, such as, for example, recommendations for customized soil and/or crop treatment compositions, irrigation practices, and/or other agricultural activity, to enhance plant health and crop productivity at the site. | 2021-01-14 |
20210010994 | METHOD FOR DETECTING OIL ON TOBACCO PRODUCTS AND PACKAGING - A process for detecting oil or lubricant contamination in a manufactured product, the process comprising adding at least two fluorescent taggants to oils or lubricants contained in processing machinery for said product, irradiating said product, causing at least one of said taggants to fluoresce and detecting radiation emitted by said fluorescing taggant in an oil-contaminated product. | 2021-01-14 |
20210010995 | MONITORING THE PERFORMANCE OF PROTECTIVE FLUIDS IN DOWNHOLE TOOLS - A method of monitoring a protective fluid of a wellbore tool includes flowing, by a sensor or a fluid moving device secured to a wellbore tool disposed at a downhole location within a wellbore, a portion of a protective fluid of the wellbore tool through a body of the sensor. The portion of the protective fluid is exposed to the body of the sensor responsive to the flowing. The protective fluid degrades over time responsive to the wellbore tool performing operations in the wellbore. The method also includes, in response to the protective fluid being exposed to the body of the sensor, determining, at least in part by the sensor, a degradation level of the protective fluid. The method also includes transmitting, by the sensor or a device communicatively coupled to the sensor, the determined degradation level to a surface of the wellbore. | 2021-01-14 |
20210010996 | MOTION DETERMINATION IN AUTOMATED TESTING APPARATUS - Embodiments include a device for testing biological specimen. The device can include a receiving mechanism to receive a carrier. The carrier may include a holding area. The device includes a camera to capture a plurality of images of the holding area. A processor in the device may utilize the camera module to: adaptively select, based on the plurality of images of the holding area, an analytical algorithm suitable for a motion property that is characteristic of the biological specimen being tested; and perform a set of analytic processes that corresponds to the selected analytic algorithm on the captured imagery to generate an analytic result associated with the biological specimen. | 2021-01-14 |
20210010997 | NANOGAP SENSORS AND METHODS OF FORMING THE SAME - In a non-limiting embodiment, a device may include a substrate having conducting lines thereon. One or more fin structures may be arranged over the substrate. Each fin structure may include a sensor arranged over the substrate and around the fin structure. The sensor may include a self-aligned first sensing electrode and a self-aligned second sensing electrode arranged around the fin structure. The first sensing electrode and the second sensing electrode each may include a first portion lining a sidewall of the fin structure and a second portion arranged laterally from the first portion. At least the first portion of the first sensing electrode and the first portion of the second sensing electrode may define a sensing cavity of the sensor. The second portion of the first sensing electrode and the second portion of the second sensing electrode may be electrically coupled to the conducting lines. | 2021-01-14 |
20210010998 | SAMPLE ACQUISITION INFORMATION MANAGEMENT DEVICE, SAMPLE ACQUISITION INFORMATION MANAGEMENT SYSTEM, AND SAMPLE ACQUISITION INFORMATION MANAGEMENT METHOD - There are provided a sample acquisition information management device, a sample acquisition information management system, and a sample acquisition information management method that allow a subject who is to collect a sample by oneself to reliably perform a sample acquisition operation. Each of the sample acquisition information management device and the sample acquisition information management system includes an image acquisition unit ( | 2021-01-14 |
20210010999 | SYSTEM AND METHOD FOR INDICATING THE PRESENCE OF MAMMALIAN BLOOD OR OTHER MAMMALIAN BODILY FLUID - A system and method of indicating the presence of mammalian blood or other mammalian bodily fluid includes receiving ambient air at an air inlet of a hand-held sensing device and sensing a chemical component of mammalian blood or other mammalian bodily fluid in the ambient air at a sensor disposed near the air inlet of the sensing device. The system and method includes using an electronic control circuit to determine the presence of the chemical component by discriminating the chemical component of mammalian blood or other mammalian bodily fluid from other odors in the ambient air and providing an audible and/or visual and/or vibrator indication when the presence of the chemical component is determined. | 2021-01-14 |
20210011000 | BIOANALYTICAL ANALYSIS OF SITE-SPECIFIC ANTIBODY DRUG CONJUGATES - Methods to rapidly and accurately detect, characterize, measure, and quantify site-specific antibody drug conjugates, that may be present in pre-clinical animal biological samples, or human biological samples, including plasma/serum and tissue samples. | 2021-01-14 |
20210011001 | ASSAYING CELLS AND NON-CELL ANALYTES IN A SAMPLE IN PARALLEL - Among other things, the present invention is related to bio/chemical sampling, sensing, assays and applications. | 2021-01-14 |
20210011002 | COMPOSITIONS AND METHODS FOR IMPROVING SENSITIVITY IN CELL BASED ASSAYS - Compositions and methods are provided that reduce the time required for detection of botulinum neurotoxins in cell-based assays. In one aspect an isoquinolynyl compound can be used for this purpose. In such cell-based assays the cell can include an enzyme that facilitates degradation of the reporter significantly faster after the cleavage than before the cleavage, and presence of the Botulinum toxin correlates with reduction of the signal from a baseline signal. The cell can advantageously express both the construct that includes the reporter, and an enzyme that facilitates the degradation. | 2021-01-14 |
20210011003 | COMPONENT ANALYSIS DEVICE, DRUG COMPONENT ANALYSIS DEVICE, COMPONENT ANALYSIS METHOD, AND DRUG COMPONENT ANALYSIS METHOD - Provided is a component analysis device, which comprises an analysis unit for measuring a component fed to the plurality of containers and analyzing the component thus measured, wherein the plurality of containers are at least a first container and a second container, wherein the first container retains a first solution containing a substance that releases adhesion between multiple cells forming the liver cell tissue, and the second container retains a buffer solution, and wherein the analysis unit measures an amount of the component discharged from the liver cell tissue in the first container into the first solution and an amount of the component discharged from the liver cell tissue in the second container into the buffer solution in the second container, and analyzes an amount of the component to be discharged via a bile duct in the liver cell tissue. | 2021-01-14 |
20210011004 | METHOD FOR CHANGING CONDITION OF EYELID OF HAIRLESS ANIMAL - A method for changing a condition of an eyelid of a hairless animal, a model animal for evaluating a therapeutic or prophylactic effect against an eyelid disease obtained by the method, a method for producing the model animal, a method of screening using the model animal and a substance having a therapeutic or prophylactic effect against an eyelid disease selected by the method of screening, and a therapeutic or prophylactic agent against an eyelid disease containing the substance as an active ingredient. | 2021-01-14 |
20210011005 | SYSTEMS AND METHODS FOR EVALUATING IMMUNE RESPONSE TO INFECTION - Systems and methods for characterizing immune response to infection using cellular analysis, such as a hematological cellular analyzer. In some instances, the immune response may be characterized as normal or abnormal based on one or more blood cell population parameters. In some instances, abnormal characterization may be used to identify patients with sepsis or at elevated risk of developing sepsis. | 2021-01-14 |
20210011006 | ENGINEERED IMMUNE CELLS AS DIAGNOSTIC PROBES OF DISEASE - Embodiments of genetically engineered immune cells are described herein which provide a new class of cell-based in vivo sensors useful for ultrasensitive disease detection based on the ability of immune cells to migrate to a site of pathology. The cell-based sensors provide an approach to early cancer detection and allow the use of the engineered immune cells in monitoring of diverse disease states including, but not limited to, cancer. | 2021-01-14 |
20210011007 | FLUORESCENT PREMIX PARTICLES, FLUORESCENT STAIN CONTAINING SAME, AND FLUORESCENT STAINING METHOD IN WHICH THESE ARE USED - The present invention relates to fluorescent premix particles, a fluorescent stain containing the same, and a fluorescent staining method in which these are used, and the fluorescent premix particles are particles including: phosphor integrated particles that are modified with a first reactive substance; and at least one target protein-binding substance that is modified with a second reactive substance and is selected from the group consisting of an antibody and an aptamer, wherein the phosphor integrated particles and the at least one target protein-binding substance are linked by interaction between the first reactive substance and the second reactive substance. | 2021-01-14 |
20210011008 | AMYLOID-BINDING COMPOUNDS AND METHODS OF USE THEREOF - A method of screening for amyloid-binding compounds, amyloid-binding compounds, and a method of detecting amyloid-β (Abeta) plaques in a subject are disclosed. The method of screening for amyloid-binding compounds includes combining amyloid, a dye, and at least one test compound to form a sample solution; equilibrating the sample solution; measuring a fluorescence signal of the sample solution; and comparing the measured fluorescence signal of the sample to a control; wherein attenuation of the fluorescence signal, as compared to the control, indicates that one or more of the test compounds bind amyloid. The amyloid-binding compound includes a compound detected by the screening method. The method of detecting amyloid-β (Abeta) plaques in a subject includes administering one or more of the amyloid-binding compounds to the subject, and detecting the compound within the subject. | 2021-01-14 |
20210011009 | METHOD AND APPARATUS FOR ANALYSING SKIN-PRINTS - A method of analysing a skin-print comprising the steps of providing a porous substrate, the porous substrate extending in a substrate plane and being substantially planar and having a first end and a second end, wherein the second end tapers to a point. The method further comprises: applying to the porous substrate a skin-print to be analysed; applying a fluid to the porous substrate; applying a voltage between the first end of the porous substrate and ground to generate an electric field, by which droplets of the fluid are ionised and emitted from the point in the form of a Taylor cone; and analysing the ionised droplets using a mass spectrometer. | 2021-01-14 |
20210011010 | APPARATUS AND METHOD FOR ABSOLUTE QUANTIFICATION OF BIOMARKERS FOR SOLID TUMOR DIAGNOSIS - Provided is a method for quantitative analysis of a sample. The method includes steps of (a) providing a singular marker representative of one or more features of the sample, the sample comprising a population of individual units of the marker; (b) measuring the marker with dot blot analysis, wherein the quantitation result is an absolute amount of the marker's population of individual units in the sample, normalized by the sample volume or by the sample weight; and (c) obtaining an objective determination of the one or more features of the sample based on the quantitation result of the marker. Also disclosed is a reference database and a method to use the reference database for diagnosing cancer in a patient. | 2021-01-14 |
20210011011 | Optical Nano-Biosensing System and Method Thereof - An optical nano-biosensing system and a method thereof are provided. The optical nano-biosensing system includes a nano-plasmonic sensing device, a high-resolution analog-to-digital converter, a signal acquisition and processing device, and an intelligent electronic device. The nano-plasmonic sensing device further includes a light-source control circuit, a sample receiver, a light detector, and a signal-amplifying circuit. The sample receiver receives a sample. The light-source control circuit generates an incident light from a light source to be projected onto the sample receiver. The light detector detects an emergent light from the sample receiver to generate a detection signal. The signal-amplifying circuit converts the detection signal to generate an amplified signal. The high-resolution analog-to-digital converter digitizes the amplified signal to generate a digital signal. The signal calculator of the signal acquisition and processing device operates the digital signal to generate calculated information. | 2021-01-14 |
20210011012 | LINKER OF BIOPROBES - A linker of bioprobes, suitable for immobilizing a bioprobe on a chip substrate of a sensor, includes SH—(CH)n-NH2, SH—(CH)n-COOH, SH—(CH)n-SH, (OH)m-(CH)n-COOH or (OH)m-(CH)n-NH2, having a carbon number of 6 or more, m and n being integers greater than 1. When an average surface roughness (Ra) of the chip substrate is greater than 250 nm, coverage of the linker on the chip substrate is 40%-80%. A further linker of bioprobes, includes SH—(CH)n-NH2, SH—(CH)n-COOH, SH—(CH)n-SH, (OH)m-(CH)n-COOH or (OH)m-(CH)n-NH2, having a carbon number of less than 6, m and n being integers greater than 1. When an average surface roughness (Ra) of the chip substrate is less than 250 nm, coverage of the linker on the chip substrate is 65%-100%. The optimal carbon chain length of the linker and the coverage are realized for substrates of various roughnesses, and grasping ability of an electrochemical sensor chip for a detected object are enhanced. | 2021-01-14 |
20210011013 | Novel Biochip Substrate, Preparation Method and Application Thereof - The present disclosure discloses a novel biochip substrate, a preparation method and an application thereof. The surface of the novel biochip substrate contains active vinyl sulfone groups. The preparation method involves a one-step reaction of a compound containing vinyl sulfone groups on both ends with a silicon-hydroxyl group on the surface of a silicon-based biochip substrate material under catalytic conditions, to prepare the biochip substrate. The application immobilizes biomacromolecules by conducting Michael addition of amino or sulfydryl group in biomacromolecules and the vinyl sulfone group on the surface of the biochip substrate, realizing biological functionalization thereof. The biochip substrate has high-density active vinyl sulfone groups, which can be used for immobilization of various biomolecules with mild fixation conditions and simple operation. The preparation method does not require complex pretreatment processes, and has high operability and reproducibility, low cost, mild reaction conditions, simple operation, and environmentally friendly, which is a broad-spectrum biochip substrate with great potential. | 2021-01-14 |
20210011014 | DETECTION AND ASSAY DEVICES AND METHODS OF MAKING AND USING THE SAME - An article such as a biomolecular detector or biosensor having a nonfouling surface thereon includes:(a) a substrate having a surface portion; (b) a linking layer on the surface portion; and (c) a polymer layer formed on the linking layer; and (d) a first member of a specific binding pair (e.g., a protein, peptide, antibody, nucleic acid, etc.) bound to the polymer layer. Methods of making and using the articles are also described. | 2021-01-14 |
20210011015 | IN SITU-GENERATED MICROFLUIDIC ASSAY STRUCTURES, RELATED KITS, AND METHODS OF USE THEREOF - In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures. | 2021-01-14 |
20210011016 | ENZYME-AMPLIFIED LATERAL FLOW DEVICE - The invention concerns a lateral flow assay device for determining the presence of an analyte in a liquid sample; the use of said device to test for the presence of an analyte in a liquid sample; and a method for determining the presence of an analyte in a liquid sample 5 involving the use of said device. | 2021-01-14 |
20210011017 | BOVINE HERPESVIRUS DETECTION AND TREATMENT - Methods, compositions, devices, and kits are described herein that are useful for detecting BoHV-1 infection in animals and/or for distinguishing animals that may benefit from administration of BoHV-1 tmv vaccine. | 2021-01-14 |
20210011018 | ADVANCED BIOPHYSICAL AND BIOCHEMICAL CELLULAR MONITORING AND QUANTIFICATION USING LASER FORCE CYTOLOGY - The present invention is directed to intelligent algorithms, methodologies and computer-implemented methodologies for biophysical and biochemical cellular monitoring and quantification enabling enhanced performance and objective analysis of advanced infectivity assays including neutralization assays and adventitious agent testing using fluidic and optical force-based measurements. | 2021-01-14 |
20210011019 | MPL MUTATIONS IN JAK2 V617F NEGATIVE PATIENTS WITH MYELOPROLIFERATIVE DISEASE - The invention provides compositions and methods for diagnosing a patient as having a myeloproliferative disease by identifying mutations in the MPL gene or gene products. | 2021-01-14 |
20210011020 | INTEGRIN ALPHA V AS A PROTEIN MARKER FOR DIAGNOSING PROSTATE CANCER - The invention relates to the field of biology and medicine, specifically to oncology, and can be used for diagnosing prostate cancer. For this purpose, use is made of a novel prostate cancer marker, which can be identified in the urine of a patient and constitutes of integrin-alpha V level or a fragment thereof. A method of diagnosing prostate cancer, comprising identifying integrin-alpha V in the urine of a patient, and a kit for carrying out the diagnosis, comprising at least one antibody specific to integrin-alpha V, or a functional fragment thereof, are also proposed. The invention makes it possible to carry out a non-invasive diagnosis of prostate cancer using a simple, sensitive and reliable method, which can be used under standard clinical laboratory conditions in inpatient or outpatient medical institutions. | 2021-01-14 |
20210011021 | Glycan-Interacting Compounds and Methods of Use - The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include monoclonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. Further provided are methods of using glycan-interacting antibodies to target cells and treat disease. | 2021-01-14 |
20210011022 | ANTI-GITR ANTIBODIES FOR CANCER DIAGNOSTICS - Provided herein are diagnostic antibodies that bind to glucocorticoid-induced tumor necrosis factor receptor (GITR). Such antibodies are useful for methods of detecting the expression of GITR in biological samples, for example, tumor tissue, and identifying a cancer patient likely to respond to anti-GITR immunotherapy or predicting whether a cancer patient will respond to anti-GITR immunotherapy. | 2021-01-14 |
20210011023 | MULTIPLEX HER2 AND ESTROGEN RECEPTOR CO-STAINING ASSAYS FOR DETECTING TUMOR HETEROGENEITY - Disclosed herein are methods for detecting the presence and/or amount of HER2 protein, HER2 nucleic acid (for example, HER2 genomic DNA), ER protein, and Chromosome 17 centromere DNA in a single sample. Samples stained for HER2 protein, HER2 DNA, ER protein, and Chromosome 17 DNA allow for the identification of various types of cancer cells, for example HER2 protein positive/ER protein positive/HER2 gene positive cells, HER2 protein positive/ER protein negative/HER2 gene positive cells, HER2 protein negative/ER protein positive/HER2 gene positive cells, and HER2 protein negative/ER protein negative/HER2 gene positive cells. | 2021-01-14 |
20210011024 | METHODS FOR DISCOVERING THERAPEUTIC TARGETS - Disclosed are methods and devices to provide efficient methods and systems for discovering therapeutic targets, novel antigens, and for deciphering an immunosignature. The invention discloses methods for the identification of unique peptides which form an immunosignature. The invention can be applied to target identifying screening in drug discovery. | 2021-01-14 |
20210011025 | METHODS AND COMPOSITIONS FOR ASSESSING ANTIBODY SPECIFICITIES - The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The of an antibody specificity in method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition. | 2021-01-14 |
20210011026 | REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS - Given a set of therapeutic epitopes, a cassette sequence is designed to reduce the likelihood that junction epitopes are presented in the patient. The cassette sequence is designed by taking into account presentation of junction epitopes that span the junction between a pair of therapeutic epitopes in the cassette. The cassette sequence may be designed based on a set of distance metrics each associated with a junction of the cassette. The distance metric may specify a likelihood that one or more of the junction epitopes spanning between a pair of adjacent epitopes will be presented. | 2021-01-14 |
20210011027 | IN VITRO METHOD FOR DETECTING INTESTINAL BARRIER FAILURE IN ANIMALS BY DETERMINING OVOTRANSFERRIN - The present invention pertains to an in vitro method for detecting intestinal barrier failure in animals, the method comprising the following steps: a) collecting intestinal sample material of an individual animal or of an animal population; and b) determining the amount of at least one protein marker contained in said sample material; wherein the at least one protein marker comprises or consists of ovotransferrin or a functional fragment thereof, and wherein an increased amount of said at least one protein marker contained in said sample versus a reference sample indicates intestinal barrier failure. | 2021-01-14 |
20210011028 | BIOMARKER DETECTION PROCESS AND ASSAY OF NEUROLOGICAL CONDITION - The subject invention provides a robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject. The invention provides measurement of two or more biomarkers in a biological fluid such as CSF or serum resulting in a synergistic mechanism for determining the extent of neurological damage in a subject with an abnormal neurological condition and for discerning subtypes thereof or tissue types subjected to damage. | 2021-01-14 |
20210011029 | BIOLOGICAL DEVICES AND METHODS OF USE THEREOF FOR THE DETECTION OF AMYLOID PROTEINS - Described herein are devices and methods for simultaneously expressing amyloid precursor protein and TonB protein. These devices and methods increase the production of these two proteins while also minimizing costs, making the proteins more widely accessible for medical research purposes, including the development of diagnostic tests for numerous diseases associated with elevated production of amyloid proteins. The amyloid precursor protein and TonB produced by the devices and methods described herein, as well as the devices themselves, can be used in experiments designed to model the interactions between metals and amyloids such as β-amyloid that are characteristic of numerous diseases such as Alzheimer's. Finally, provided herein are diagnostic tests that can detect Alzheimer's disease in samples from patients; the tests are sensitive enough to identify diseases such as Alzheimer's even at pre-clinical stages, before the appearance of symptoms. | 2021-01-14 |
20210011030 | BLOCKADE OF TIM-1 PATHWAYS and P-SELECTIN PATHWAYS IN TREATMENT OF NEUROINFLAMMATORY DEGENERATIVE DISEASE - Methods for treating, preventing and reducing the progression of neurodegenerative and neurological diseases, including, without limitation Alzheimer's disease, are provided. The methods of the invention inhibit one or both of TIM-1 and P-selectin function and reduce leukocyte and platelet cell adhesion, activation and interaction with the vascular endothelium and infiltration of leukocytes into the brain. | 2021-01-14 |
20210011031 | COMPOSITION FOR SCREENING ONGOING PROGRESS OF ALZHEIMER'S DISEASE BY USING BETA AMYLOID OLIGOMER IN NASAL DISCHARGE SPECIMEN AND METHOD FOR SCREENING ONGOING PROGRESS OF ALZHEIMER'S DISEASE BY USING SAME - The present invention relates to a composition for screening ongoing progress of Alzheimer's disease using beta amyloid of a nose discharge sample and a method of screening ongoing progress of Alzheimer's disease using the same, more specifically, to a composition and a kit for screening ongoing progress of Alzheimer's disease, comprising an agent measuring an expression level of a 56 kDa beta amyloid oligomer and a 72 kDa beta amyloid oligomer in an nose discharge sample, and a method of screening ongoing progress of Alzheimer's disease comprising measuring the expression level of the 56 kDa and 72 kDa beta amyloid oligomers in an nose discharge sample. | 2021-01-14 |
20210011032 | METHODS AND REAGENTS FOR IMPROVED DETECTION OF AMYLOID BETA PEPTIDES - The invention relates to methods for the diagnostic of a neurodegenerative disease, for the detection of a stage prior to a neurodegenerative disease or for distinguishing neurodegenerative disease from a stage prior to a neurodegenerative disease based on the level of certain pools of amyloid beta peptides which are either bound to plasma components or bound to blood cells as well as on certain calculated parameters which are obtained by an arithmetic combination of one or more of the amyloid peptide levels. The invention relates as well to kits for carrying out the above method. | 2021-01-14 |
20210011033 | METHODS AND COMPOSITIONS FOR QUANTIFYING HEMOGLOBIN - The present invention relates to methods and compositions for quantifying hemoglobin using, inter alia, a peroxidase substrate and hydrogen peroxide. | 2021-01-14 |
20210011034 | METHOD FOR PREDICTING THE RISK OF OBESITY IN A SUBJECT - Subject matter of the present invention is a method for determining the fat processing activity and/or predicting the risk of obesity in a subject comprising the following steps determining the level of pro-neurotensin or fragments thereof of at least 5 amino acids in a bodily fluid obtained from said subject; and correlating said level of pro-neurotensin or fragments thereof with fat processing activity and/or the risk of incidence of obesity in said subject, wherein an elevated level is indicative of enhanced fat processing activity and/or predictive for an enhanced risk of getting obesity. | 2021-01-14 |
20210011035 | A RAPID, ON-DEMAND HEPARIN-INDUCED THROMBOCYTOPENIA FUNCTIONAL ASSAY - A method for assaying a heparin-induced thrombocytopenia (HIT) in a patient's serum or plasma sample, the method comprising: incubating a mix of platelets with the patient's serum or plasma sample in the presence of either a low concentration of heparin or a high concentration of heparin; incubating a mix of platelets in the presence or absence of a platelet activator; quantifying platelets and activated platelets in the mixes; calculating percentage of activated platelets within the platelets for each of the mixes; calculating a heparin platelet activation (HEPLA) index using the calculated percentages; measuring and calculating HEPLA indices of serum or plasma samples from donors not suffering from HIT; calculating cut-off values from the HEPLA indices of serum or plasma samples from donors not suffering from HIT, and determining whether a patient suffers of HIT or not by comparing the HEPLA index of the patient with the cut-off values. | 2021-01-14 |
20210011036 | QUANTIFICATION METHOD, QUANTIFICATION REAGENT AND QUANTIFICATION KIT FOR LIPOPROTEIN CHOLESTEROL - Provided are a method which enables more accurate quantification of lipoprotein cholesterol in a test sample, and a quantification reagent and a quantification kit used for this method. The present invention provides a quantification method for lipoprotein cholesterol in a test sample containing a lipoprotein optionally using a quantification reagent, the method including adding a phospholipid to the test sample or the quantification reagent. The present invention also provides a quantification reagent for cholesterol in a lipoprotein used in the method of the present invention, the quantification reagent containing a phospholipid. The present invention also provides a quantification kit for lipoprotein cholesterol used in the method of the present invention, the quantification kit containing a phospholipid. | 2021-01-14 |
20210011037 | LATERAL FLOW IMMUNOASSAYS FOR THE DETECTION OF ANTIBODIES AGAINST BIOLOGICAL DRUGS - A lateral flow immunoassay for the detection of anti-drug antibodies against a biological drug includes a membrane having a capture area, a sample application area, a flow path from the sample application area to the capture area, and a conjugate area located in the flow path. The conjugate area has said biological drug detectably labeled and the capture area has said biological drug immobilized thereto. | 2021-01-14 |
20210011038 | Automated Dissolution/Permeation Testing System - Combined dissolution rate and permeation rate testing apparatus includes temperature-controllable testing cell units arranged on a housing frame. Each testing cell unit includes a donor chamber receivable of dissolution media, a receptor chamber receivable of bodily fluid, gaskets that retain a membrane between the two chambers, and controllable mixers that mix the fluid in the receptor chamber. A flow control arrangement operatively circulates dissolution media through the donor chamber and enables sampling of the dissolution media. Another flow control arrangement operatively circulates bodily fluid through the receptor chamber. An analysis unit analyzes dissolution media removed from the donor chamber and bodily fluid removed from the receptor chamber to provide data about dissolution of a pharmaceutical product dissolved in the dissolution media and permeation of the pharmaceutical product through the membrane into the bodily fluid. | 2021-01-14 |
20210011039 | METHOD OF TRANSPORTING RACK AND SAMPLE MEASUREMENT SYSTEM - A sample measurement system according to an embodiment may include: sample measurement units that receive supply of containers and perform measurement on samples; a rack setting unit in which a rack storing the containers to be supplied to at least one of the sample measurement units is set; a first transport path that transports the containers from the rack setting unit to at least one of the sample measurement units; a second transport path that is provided at a position different from the first transport path in a height direction and that transports the containers from at least one of the sample measurement units to the rack setting unit; and a transfer path that transfers the containers between the first transport path and the second transport path. | 2021-01-14 |
20210011040 | SAMPLE MEASUREMENT SYSTEM AND METHOD OF TRANSPORTING RACKS - A sample measurement system according to an embodiment may include: sample measurement units that perform measurement on samples by using consumables; a consumable setting unit in which a consumable rack storing the consumables to be supplied to the sample measurement units is set; a sample setting unit in which a sample rack storing the samples to be supplied to the sample measurement units is set; a first transport path that transports the consumable rack from the consumable setting unit to at least one of the sample measurement units; and a second transport path that transports the sample rack from the sample setting unit to at least one of the sample measurement units. | 2021-01-14 |
20210011041 | SAMPLE MEASUREMENT SYSTEM AND METHOD OF TRANSPORTING RACKS - A sample measurement system and method of transporting of racks are provided that collectively supply the consumables to the sample measurement units. The sample measurement system includes: sample measurement units that perform measurement on samples by using consumables; a setting part in which a user sets consumable racks housing the consumables; a first transport path that supplies the consumable racks set in the setting part to one of the sample measurement units; a collector that is arranged adjacent to the setting part and that collects empty racks that are emptied after being transported to at least one of the sample measurement units; and a second transport path that transports the empty racks to the collector. | 2021-01-14 |
20210011042 | INTEGRATED CARTRIDGE SERVICE STATION - An integrated cartridge service station may include a reagent module comprising at least one reagent ejection device, and a service module integrated with the reagent module. The service module may include at least one service device. The reagent module and the service module are movable with respect to one another within a reagent dispensing system. The at least one reagent ejection device is movable between an in-line position and an off-line position within the reagent dispensing system. | 2021-01-14 |
20210011043 | REAGENT DEPOSITION VERIFICATION - A reagent substrate may include a reagent sample deposition area on which a sample of a reagent is deposited, and a number of diagnostic regions on which a diagnostic sample of the reagent is deposited for verification of deposition of the diagnostic sample. A reagent dispensing system may include a conveyor surface to convey a number of substrates, at least one reagent module located in-line with respect to the conveyor surface where the reagent module includes at least one reagent dispensing device to dispense a reagent on the substrates, and at least one optical sensor to verify the dispensing of the reagent at a number of diagnostic regions of the substrate. | 2021-01-14 |
20210011044 | Automated Analyzer and Method of Controlling the Automated Analyzer - An automated analyzer including: a stirring part provided with a stirring bar; a cleaning part that cleans the stirring bar; and a control unit that controls the stirring part and the cleaning part, when the control unit causes the stirring part to stir a liquid containing a specimen in a second cycle subsequent to a first cycle, the control unit performing first processing that sets a range of the stirring bar to be cleaned in the second cycle as a cleaning range R | 2021-01-14 |
20210011045 | DNA CONCENTRATE DISPENSING - Examples disclosed herein relate to a device. Examples include a region selection engine to determine a plurality of regions on a well plate, a number of wells in each region, and a location of each well in each region; and a dispense engine to determine a quantity of DNA concentrate to dispense in each well of the plurality of regions on the well plate, and the dispense engine to control a fluid dispensing device to eject the quantity of DNA concentrate into each well of each region of the well plate. In examples, a quantity of DNA fragments in the DNA concentrate is unknown. | 2021-01-14 |
20210011046 | SAMPLE PROCESSING AND DETECTING KIT WITH A MATERIAL TRANSFER STRUCTURE - A sample processing and detecting kit with a material transfer structure comprises a kit body defined by an outer shell. A top outer shell of the kit body comprises an opening-and-closing sample port. An inner side of the kit body is disposed with a material circular plate holder and a middle of the material circular plate holder is disposed with a circular hole. A waste liquid storage chamber, a first lock groove, a second lock groove, and a sealing hole are arranged on the material circular plate holder at a periphery of the circular hole. A sample processing plastic tube member is hermitically disposed in the first lock groove. A detection reaction plastic tube member is hermetically disposed in the second lock groove. | 2021-01-14 |
20210011047 | ACCELEROMETER WITH BUILT-IN TEMPERATURE CORRECTION - Systems and methods are disclosed for generating temperature compensated acceleration data in analog and digital format from a torque balance accelerometer (TBA). During manufacture of the TBA, a calibration process is used for measuring a TBA scale factor and offset. After collecting scale and offset data, said data is loaded into the memory of the TBA. Field operation of the device includes: sensing a current temperature, retrieving the closest scale and offset correction factors from memory of the TBA, and performing linear interpolation to generate a temperature-compensated output for the TBA. | 2021-01-14 |
20210011048 | Processing Downhole Rotational Data - Systems and methods for processing downhole rotational data. An example method includes commencing operation of a processing device to continually calculate a downhole oscillation index by receiving downhole rotational speed data indicative of downhole rotational speed of at least a portion of a drill string during drilling operations, calculating a fundamental oscillation time period of the drill string, calculating a time length of a time window based on the fundamental oscillation time period, and processing the downhole rotational speed data encompassed within the time window. | 2021-01-14 |
20210011049 | DETERMINATION OF RPM FROM VIBRATION SPECTRAL PLOTS - A vibration analyzer for use in determining a rotational speed. The vibration analyzer includes an input for sensing vibration data, a memory for storing the vibrational data, and a processor. The processor produces a spectral plot of the vibrational data, locates peaks in the spectral plot, receives an input rotational speed, and scans the spectral plot in predetermined rotational speed increments to provide a candidate rotational speeds. For each candidate rotational speed, a number of associated harmonics is identified, closest peaks in the spectral plot to the candidate rotational speed and its harmonics are located, gaps between the closest peaks and the candidate rotational speed and its harmonics are measured and summed, and a sum of the gaps is recorded. The candidate rotational speed that is associated with a minimum sum is selected as the nominal rotational speed. | 2021-01-14 |
20210011050 | LIGHTNING-PROOF PIEZOELECTRIC ACCELERATION SENSOR - The present application relates to the technical field of sensors, and particularly relates to a lightning-proof piezoelectric acceleration sensor which comprises a housing, a core assembly, an insulation sheet, a shielding cover, a lightning-proof circuit board and a heat-shrinkable sleeve, the core assembly is provided inside the housing, the insulation sheet has one end fixedly connected to the core assembly and the other end fixedly connected to an inner wall of the housing, the shielding cover is sleeved outside the core assembly and has an open end oriented towards the insulation sheet, the lightning-proof circuit board is fixedly provided on an upper end of the shielding cover and is electrically connected to an external connector and the core assembly respectively, the heat-shrinkable sleeve is sleeved outside the shielding cover and has a lower end connected to the housing and an upper end situated higher than the shielding cover. | 2021-01-14 |
20210011051 | PIEZOELECTRIC ACCELERATION SENSOR - The present application relates to a piezoelectric acceleration sensor, comprising a base member that comprises a supporting part provided with a mounting hole extending along an axis thereof and a columnar connection part located on the connection part; a piezoelectric member, sleeved outside the connection part, and defining with the connection part an annular clearance therebetween; a mass block member, sleeved outside the piezoelectric member in a gapless manner; a pre-tightening member, being a wedge block with a thinner end near the supporting part and inserted into the annular clearance; a locking member that comprises an interconnected columnar part and stopping part; wherein, the columnar part is fitted with the mounting hole for locking the above members, and the stopping part is arranged to press the first end; the columnar part and the mounting hole are provided with fastening glue arranged between. | 2021-01-14 |
20210011052 | SCANNING PROBE MICROSCOPE - A scanning probe microscope includes: a pump light output unit that emits pump light having a first specified phase to a specimen and performs emission of the pump light a plurality of number of times to excite the specimen; a probe light output unit that emits probe light having a second specified phase to the specimen once while the specimen is excited by one-time emission of the pump light; and a scanning probe that detects, from the specimen, a probe signal corresponding to each one-time emission of the probe light, wherein the pump light output unit or the probe light output unit includes a delay time adjustment unit that adjusts delay time from a start of the emission of the pump light until a start of the emission of the probe light. | 2021-01-14 |
20210011053 | Method And Apparatus Of Atomic Force Microscope Based Infrared Spectroscopy With Controlled Probing Depth - A method for obtaining optical spectroscopic information about a sub-micron region of a sample with quantitatively controlled depth/volume of the sample subsurface using a scanning probe microscope. With controlled probing depth/volume, the method can separate top surface data from subsurface optical/chemical information. The method can also be applied in liquid suitable for studying biological and chemical samples in their native aqueous environments, as opposed to air. In the method, a depth-controlled spectrum of the surface layer is constructed by illuminating the sample with a beam of infrared radiation and measuring a probe response using at least one of the resonant frequencies of the probe. The surface sensitivity is obtained by limiting the heat diffusion effect of the subsurface so as to confine the signal. The signal confinement is achieved through non-linearity of the acoustic wave with probe, as well as benefits gained by a high modulation frequency of the infrared radiation source at > | 2021-01-14 |
20210011054 | SECURE HOLDER FOR PROBE AND TEST JIG USING THE SAME - A probe holder for securely holding a probe within a certain location includes a base and a limiting block. The base defines a first receiving cavity having a bottom. The bottom of the first receiving cavity defines at least one first through hole penetrating the base. The first through hole is stepped for abutting the probe in one direction. The limiting block is disposed on the base opposite to the first receiving cavity. The limiting block defines at least one second through hole corresponding to the first through hole, the second through hole is also stepped and serves as a second abutting portion against the probe moving in an opposite direction. A test jig using the probe holder is also provided. | 2021-01-14 |
20210011055 | Apparatus and Method for Securing an Enclosure - The present invention relates to an apparatus and method for securing a box cover to a watthour meter socket box. In certain embodiments, the apparatus has a clamping member that fits over a wall of a meter box, and a lock housing that locks to the clamping member after a box cover has been installed, thereby securing the cover to the box in a manner such that the box cover cannot be installed unless the clamping member has been installed correctly. In various other embodiments, the clamping member consists of a clamp disposed between a clamp actuating member and a fastening shelf. In various other embodiments, the clamp includes a stopping member for indicating when the clamp actuating member is actuated into a fully secured position. Other embodiments relate to a locking bracket and a lock housing wherein the locking bracket generally comprises a clamping member and a fastening lever that attaches to a wall of a meter box base. The lock housing generally comprises a unitary member with a perpendicular flange. The meter box lid is secured to the meter box base when the locking bracket is secured to the side wall (or another wall) and used in combination with the lock housing and a locking shaft. | 2021-01-14 |
20210011056 | CURRENT TRANSFORMER WITH SELF-ADJUSTING CORES - A current transformer includes a first housing including a first handle portion and a first distal portion, a second housing including a second handle portion and a second distal portion, a first core having a first proximal core end and a first distal core end the first core mounted in rotational contact within the first distal portion, and a second core having a second proximal core end and a second distal core end, the second core mounted in rotational contact within the second distal portion, wherein the first housing is rotationally coupled to the second housing about a fulcrum point. | 2021-01-14 |
20210011057 | CURRENT TRANSFORMER WITH CALIBRATION INFORMATION - A current transformer assembly includes a first current transformer, a plug, a first wire and a second wire between the plug and the first current transformer adapted to transmit a measurement of the first current transformer; and a memory chip adapted to store a first scale factor of the first current transformer. | 2021-01-14 |
20210011058 | CURRENT SENSOR AND METHOD FOR MANUFACTURING CURRENT SENSOR - Provided is a current sensor for reducing heat generation caused by energization. The current sensor is provided, including: primary terminals; a first magnetic sensor; a primary conductor; and a signal processing IC; wherein the primary conductor has a bend section including: a first region that surrounds at least a part of the first magnetic sensor in planar view and at least a part of which does not face the signal processing IC; and a second region that faces the signal processing IC; wherein the height of the first region is lower than that of the primary terminal, the height of the second region is lower than that of the first region, and the first magnetic sensor is connected to the signal processing IC through conductive wires, on the opposite side from the plane. | 2021-01-14 |
20210011059 | APPARATUS FOR MEASURE OF QUANTITY AND ASSOCIATED METHOD OF MANUFACTURING - An integrated device provides a measure of a quantity dependent on current through an electrical conductor, having: a sensing and processing sub-system; an electrical conductor conducting current; an insulating material encapsulates the sensing and processing sub-system and maintains the electrical conductor in a fixed and spaced relationship to the sensing and processing sub-system. The insulating material insulates the electrical conductor from the sensing and processing sub-system. Sensing and processing sub-system sensing circuitry includes magnetic field sensing elements adjacent the electrical conductor. The sensing circuitry provides a measure of the quantity as a weighted sum and/or difference of magnetic field sensing elements outputs caused by current through the electrical conductor adjacent the magnetic field sensing elements. A voltage sensing input senses a measure of voltage associated with the current conductor. Sensing and processing sub-system output circuitry provides an output measure of the quantity from the sensed measure of current and voltage. | 2021-01-14 |
20210011060 | LOW POWER COMPARATOR AND SELF-REGULATED DEVICE - A low power comparator and a self-regulated device for adjusting power saving level of an electronic device are provided. The low power comparator includes an input differential pair circuit, a self-regulated device, and a tail current switch. The input differential pair circuit is configured to receive input signals to be compared. The self-regulated device is coupled to the input differential pair circuit and includes a self-regulated circuit which has a first transistor with a first threshold voltage and a second transistor with a second threshold voltage and is configured to adjust a power saving level of the low-power comparator according to the first threshold voltage and the second threshold voltage. The tail current switch is coupled to the input differential pair circuit through the self-regulated circuit to provide a constant current to the input differential pair circuit. | 2021-01-14 |
20210011061 | Harmonics Measurement in Power Grids - The subject-matter relates to a method, performed by at least one apparatus, including: determining of a correction factor for at least one first voltage transformer arranged in a power grid, the correction factor being indicative of a correction for obtaining correct measured values measured by the at least one first voltage transformer, wherein the determining of the correction factor of the at least one first voltage transformer being performed at least partially based on a first measured voltage of the at least one first voltage transformer and a second measured voltage of the at least one first voltage transformer, wherein the second voltage of the at least one first voltage transformer is determined at least partially based on a known transfer function of at least one second voltage transformer and the first voltage of the at least one first voltage transformer is determined without taking into account the known transfer function of the at least one second voltage transformer; determining a calibration factor for the at least one first voltage transformer based at least in part on the determined correction factor; and outputting or causing the output of the determined calibration factor. The subject matter further relates to a correspondingly configured apparatus and a system. | 2021-01-14 |
20210011062 | METHOD AND SYSTEM FOR LOW SAMPLING RATE ELECTRICAL LOAD DISAGGREGATION - This disclosure relates generally to method and system for low sampling rate electrical load disaggregation. At low sampling rates, disaggregation of energy load is challenging due to unavailability of events and signatures of the constituent loads. The disclosed energy disaggregation technique receives aggregated load data from a utility meter and sequentially obtains training data for determining disaggregated energy load at low sampling rate. Dictionaries are used to characterize the different loads in terms of power values and time of operation. The obtained dictionary coefficients are treated as graph signals and graph smoothness is used for propagating the coefficients from the training phase to the test phase by formulating an optimization model. The derivation of the optimization model identifies the load of interest and estimate their power consumption based on optimization model constraints. This method achieves accuracy greater than 70% for the loads of interest at low sampling rates. | 2021-01-14 |
20210011063 | Method for Operating a Power Consumption Metering System and Power Consumption Metering System - A method for operating a power consumption metering system and a power consumption metering system are disclosed. In an embodiment a method includes measuring, by a sensor deployed at a monitored site, power consumption values over time to obtain a value pattern of a power consumption, providing the value pattern to a cloud based data processing system, identifying a status of a power consumer of the monitored site dependent on the value pattern and counting an operation time of the power consumer dependent on the identified status. | 2021-01-14 |
20210011064 | PROCESSING DEVICE AND METHOD FOR CHANGING FUNCTION OF PINS - A detection method for a USB Type-C connector is provided. The detection method is applied to a dual role port (DRP) device. The detection method includes the following steps: in response to the DRP device being in a Try. SRC state, detecting whether there is a sink device connected to the DRP device; in response to detecting a sink device connected to the DRP device, switching the current source provided to the pull-up resistor connected to the CC pin from the first current value to the second current value, and detecting again whether there is a sink device connected to the DRP device, wherein the first current value is greater than the second current value; and in response to detecting a sink device connected to the DRP device, the DRP device enters an Attached. SRC state. | 2021-01-14 |
20210011065 | RESISTANCE MEASUREMENT DEVICE, FILM MANUFACTURING APPARATUS, AND MANUFACTURING METHOD OF ELECTRICALLY CONDUCTIVE FILM - A resistance measurement device for measuring sheet resistance of an electrically conductive film being long in one direction includes two probes disposed to face each other in spaced apart relation so as to allow the electrically conductive film to be interposed therebetween without contacting with the electrically conductive film; a scanning unit that allows the two probes to scan in a cross direction crossing the one direction; and an arithmetic unit that calculates a sheet resistance of the electrically conductive film based on a voltage measured by the two probes. The arithmetic unit includes a memory that memorizes a reference voltage measured by allowing the two probes to scan in the cross direction without interposing the electrically conductive film between the probes. The arithmetic unit corrects an actual voltage by allowing the two probes to scan in the cross direction with the electrically conductive film being interposed between the probes. | 2021-01-14 |
20210011066 | CIRCUIT FOR MEASURING A RESISTANCE - A circuit for measuring an unknown resistance of a resistive element comprises a sensor circuit to generate a differential voltage dependent on the resistance of the resistive element and a reference circuit to generate a differential reference voltage and a sigma-delta converter comprising a first stage, wherein a first capacitor is selectively coupled to one of the output terminals of the sensor circuit and a second capacitor is coupled to one of the output terminals of the reference circuit. The circuit generates logarithmically compressed values. | 2021-01-14 |
20210011067 | SYSTEM AND METHOD FOR DETERMINING THE IMPEDANCE PROPERTIES OF A LOAD USING LOAD ANALYSIS SIGNALS - Various embodiments are described herein for measuring the impedance properties of a load using load analysis signals. In one example embodiment, a transformer is provided which includes at least one primary winding, and at least one secondary winding. The at least one primary winding is coupled in series between a direct-current (DC) power supply and the load. A variable alternating-current (AC) voltage generator is coupled in-series to the at least one secondary winding, and is configured generate at least one load analysis signal for injection into the load. The impedance properties of the load may be determined for different frequencies in the load analysis signals. | 2021-01-14 |
20210011068 | FULLY DISTRIBUTED MAGNETIC ADSORPTION MULTI-PARAMETER SENSING CABLE - A fully distributed magnetic adsorption multi-parameter sensing cable, which is configured to be installed on the wall of a metal pipeline, includes an outer sheath, a sensing component arranged in the outer sheath, and a fully distributed magnetic adsorption reinforcement (FDMAR) arranged in the outer sheath and on a peripheral side of the sensing component. The outer sheath is attached to the wall of the metal pipeline by the FDMAR. A magnetic adsorption force between the FDMAR and the wall of the metal pipeline is able to be adjusted by changing the size of the FDMAR and the distance between the FDMAR reinforcement and the wall of the metal pipeline. The fully distributed magnetic adsorption multi-parameter sensing cable has the advantages of good adsorption effect and high sensitivity. | 2021-01-14 |
20210011069 | INTEGRATED CIRCUIT WITH ANTENNA IN PACKAGE TESTING APPARATUS - An integrated circuit with antenna in package (AiP IC) testing apparatus is provided, and includes: a carrier board, a test socket, and a receiving antenna circuit board. The test socket is disposed on the carrier board and configured to carry an AiP IC which emits a wireless signal. The receiving antenna circuit board is adjacent to the test socket and configured to receive the wireless signal. The receiving antenna circuit board and the reflector are integrated into the AiP IC testing apparatus, so that the AiP IC testing apparatus can be used not only for testing a feedback signal transmitted by a test pin of the IC, but also for testing the wireless signal from the IC. | 2021-01-14 |
20210011070 | BURN-IN CHAMBER - A burn-in chamber is provided, configured to provide the required temperature for a device under test (DUT), including a side wall, a guiding plate, an air flow plate, a partition assembly, and a fan. The air flow plate has a ventilation structure, and the guiding plate is located between the side wall and the air flow plate. The partition assembly is disposed on both sides of the air flow plate. The partition assembly and the air flow plate together form an accommodating space for accommodating the DUT. The partition assembly forms a return channel with respect to the other side of the accommodating space with the side wall. When the fan is active, air from the accommodating space passes through the air flow plate and is guided to the return channel via the guiding plate, and air is returned to the accommodating space through the return channel. | 2021-01-14 |
20210011071 | POWER DISTRIBUTION NETWORK MONITORING SYSTEM AND POWER DISTRIBUTION NETWORK MONITORING DEVICE - A power distribution network monitoring system detects abnormalities that occur in a power distribution network using measuring instruments installed in the power distribution network. The power distribution network monitoring system includes a plurality of measuring instruments that are installed at predetermined positions on power lines on an upstream side of the downmost-stream power demander, among the power lines constituting the power distribution network and configured to perform electrical measurement of the power lines; and an abnormality detector configured to determine whether or not data related to the measurement result measured by the measuring instrument has been received a predetermined number of times within a predetermined length of time, and detect the abnormality. | 2021-01-14 |
20210011072 | INSULATION MONITORING CIRCUIT FOR MOTOR CONTROLLER - An insulation monitoring electric circuit of an electric-motor controller, includes: a first voltage sampling circuit and a second voltage sampling circuit; the first voltage sampling circuit is connected to an input anode (+VBUS) of a busbar, an input cathode (PGND) of the busbar and a busbar-voltage sampled-signal (HV_VDC) line, and a busbar-voltage sampled-signal (HV_VDC) line is connected to the electric-motor controller; the second voltage sampling circuit is connected to the input anode (+VBUS) of the busbar, the input cathode (PGND) of the busbar and an insulation-voltage sampled signal (HV_VDC) line, and an insulation-voltage sampled signal (HV_VISO) line is connected to the electric-motor controller; and the electric-motor controller is configured to compare a busbar-voltage value gathered by the first voltage sampling circuit and an insulation-voltage value gathered by the second voltage sampling circuit, and when the busbar-voltage value and the insulation-voltage value are different, emit an insulation monitoring alarming signal. | 2021-01-14 |
20210011073 | DATA-DRIVEN MISREGISTRATION PARAMETER CONFIGURATION AND MEASUREMENT SYSTEM AND METHOD - A data-driven misregistration parameter configuration and measurement system and method including simulating a plurality of measurement simulations of at least one multilayered semiconductor device, selected from a batch of multilayered semiconductor devices intended to be identical, using sets of measurement parameter configurations, generating simulation data for the device, identifying recommended measurement parameter configurations, selected from sets of measurement parameter configurations, providing a multilayered semiconductor device selected from the batch, providing the at least one recommended set of measurement parameter configurations to a misregistration metrology tool having multiple possible sets of measurement parameter configurations, measuring at least one multilayered semiconductor device, selected from the batch using the recommended set, thereby generating measurement data for the device, thereafter identifying a final recommended set of measurement parameter configurations and measuring misregistration of at least one multilayered semiconductor device, selected from the batch, using the final recommended set. | 2021-01-14 |
20210011074 | SEMICONDUCTOR DEVICES INCLUDING THROUGH ELECTRODES - A semiconductor device includes a first semiconductor chip and a second semiconductor chip stacked on the first semiconductor chip and electrically connected to the first semiconductor chip by a first through electrode and a second through electrode. The first semiconductor chip may electrically connect the first through electrode to a third test resistor during a second test operation. The first semiconductor chip may detect a voltage level of the first internal node, which is determined by resistance values of the third test resistor and the first and second through electrodes, to test a short failure between the first and second through electrodes during the second test operation. | 2021-01-14 |
20210011075 | DEVICE FOR TESTING ELECTRONIC DEVICES IN ADJUSTABLE AND ACCURATE SIMULATION OF REAL-WORLD ENVIRONMENTS - A device for testing performance of main boards of electronic devices includes a housing, two bases, a control device, a humidifier, a heating device, and a refrigerating device. A cavity in the housing comprises separated first and second portions. The heating device is interconnected with the first portion to create a predefined high temperature environment and the refrigerating device is interconnected with the second portion to create a predefined low temperature environment. The humidifier is interconnected with the first portion and the second portion, and configured to create predefined degrees of humidity respectively in the first portion and the second portion. The bases are inside the first portion and the second portion, and electrically connected to the control device. | 2021-01-14 |
20210011076 | MONITORING CIRCUIT AND SEMICONDUCTOR DEVICE - Embodiments of the present disclosure relate to a monitoring circuit and a semiconductor device, and particularly, to a monitoring circuit including an oscillation circuit configured to generate an oscillation signal having a rising characteristic or a falling characteristic according to a threshold voltage level and a counter configured to count the number of rises or the number of falls of the oscillation signal, and a semiconductor device including the monitoring circuit. | 2021-01-14 |
20210011077 | SEMICONDUCTOR DEVICE, SEMICONDUCTOR MODULE, AND METHOD OF OPERATING SEMICONDUCTOR DEVICE - A semiconductor device includes: a substrate; a circuit element disposed on a first surface side of the substrate; a first transmission line disposed on the first surface side; a first terminal disposed on the first surface side; a first dielectric disposed in a part of the first transmission line; a second terminal disposed on a side of the first dielectric opposite to the first transmission line; a second transmission line disposed on the first surface side and has one end coupled to the circuit element; a third terminal disposed on the first surface side and coupled to the other end of the second transmission line; a second dielectric disposed in a part of the second transmission line; a fourth terminal disposed on a side of the second dielectric opposite to the second transmission line; and a conductor disposed on a second surface side of the substrate. | 2021-01-14 |