03rd week of 2015 patent applcation highlights part 56 |
Patent application number | Title | Published |
20150018547 | AROMATIC RING COMPOUND - The present invention provides a compound having a GOAT inhibitory action, which is useful for the prophylaxis or treatment of obesity and the like, and has superior efficacy. The present invention is a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof. | 2015-01-15 |
20150018548 | PROCESS FOR PRODUCING N-METHYL OR N,N-DIMETYL AMINES - A process for producing N-methyl or N,N-dimethyl amines, which comprises using amine compound, nitro-containing compound or nitrile compound as a starting material, carbon dioxide as a methylating agent and hydrogen gas as a reducing agent, and allowing them to react in a sealed reactor for 6 to 48 h in a reaction medium at a reaction temperature of 80 to 180 ° C. in the presence of a composite catalyst, so as to provide N-methyl or N,N-dimethyl amines. The process of the present invention is simple and under relative mild reaction conditions. By means of the process of the invention, the target products can be prepared at low cost with a high yield. The catalysts used have a high catalytic activity and can be separated from the reaction system simply and reused. Furthermore, the whole process of the present invention is environmental-friendly and facilitates the cycling use of carbon dioxide. | 2015-01-15 |
20150018549 | Metal Complexes of Cyclometallated Imidazo[1,2-f]phenanthridine and Diimidazo[1,2-a:1',2'-c]quinazoline Ligands and Isoelectronic and Benzannulated Analogs Thereof - Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described. | 2015-01-15 |
20150018550 | MULTIFUNCTIONAL SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF AND METHODS OF USE - Disclosed are multifunctional sulfur-containing polymers that are the reaction products of a sulfur-containing diol, a polyol containing at least three hydroxyl groups per polyol molecule, and an aldehyde, a ketone, or a combination thereof. Sealant compositions comprising the multifunctional sulfur-containing polymers are also disclosed. | 2015-01-15 |
20150018551 | CYCLOALKANE DERIVATIVES - Disclosed herein are therapeutic agents and/or preventive agents for pain or therapeutic agents and/or preventive agents for a sodium channel associated disease. The present invention provides compounds represented by the following formula (I) or pharmacologically acceptable salts thereof: | 2015-01-15 |
20150018552 | N-Phenyl-2-pyrimidine-amine Derivatives - The present invention relates to novel amides and a process for preparing these amides. | 2015-01-15 |
20150018553 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES - The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof. | 2015-01-15 |
20150018554 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES - The disclosure relates to a process for the preparation of the enantiomeric forms of 2,3-diaminopropionic acid derivatives of formula I, | 2015-01-15 |
20150018555 | NOVEL CHIRAL NITROGEN-PHOSPHORUS LIGANDS AND THEIR USE FOR ASYMMETRIC HYDROGENATION OF ALKENES - The invention relates to a series of novel chiral nitrogen-phosphorus ligands of formulae (Ia) and (Ib): | 2015-01-15 |
20150018557 | CATALYST COMPLEX WITH CARBENE LIGAND - Catalytic complexes including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand. The complexes are highly stable to air, moisture and thermal degradation. The complexes are designed to efficiently carry out a variety of olefin metathesis reactions. | 2015-01-15 |
20150018558 | Platinum (II) Di (2-Pyrazolyl) Benzene Chloride Analogs and Uses - Synthesis of platinum(II) di(2-pyrazolyl)benzene chloride and analogs includes forming a 1,3-di-substituted benzene including two aromatic five-membered heterocycles, and reacting the 1,3-di-substituted benzene with an acidic platinum-containing solution to form a luminescent platinum(II) complex. The luminescent platinum(II) complex is capable of emitting blue and white light and can be used as an emitter in a light emitting device. | 2015-01-15 |
20150018559 | Chelating Carbene Ligand Precursors and Their Use in the Synthesis of Metathesis Catalysts - Chelating ligand precursors for the preparation of olefin methathesis catalysts are disclosed. The resulting catalysts are air stable monomeric species capable of promoting various methathesis reactions efficiently, which can be recovered from the reaction mixture and reused. Internal olefin compounds, specifically beta-substituted styrenes, are used as ligand precursors. Compared to terminal olefin compounds such as unsubstituted styrenes, the beta-substituted styrenes are easier and less costly to prepare, and more stable since they are less prone to spontaneous polymerization. Methods of preparing chelating-carbene methathesis catalysts without the use of CuCl are disclosed. This eliminates the need for CuCl by replacing it with organic acids, mineral acids, mild oxidants or even water, resulting in high yields of Hoveyda-type methathesis catalysts. The invention provides an efficient method for preparing chelating-carbene metathesis catalysts by reacting a suitable ruthenium complex in high concentrations of the ligand precursors followed by crystallization from an organic solvent. | 2015-01-15 |
20150018560 | Process for preparing cis-5-[1-(4-chlorophenyl)-methylene]-1-hydroxymethyl-2,2-dimethylcyclopen- tanol - The present invention relates to a process for preparing a diol of the formulae (Ia) or (Ib), or a mixture thereof, | 2015-01-15 |
20150018561 | CF3O-CONTAINING ENAMINOKETONES AND THEIR UTILIZATION FOR THE PREPARATION OF CF3O-CONTAINING PYRAZOLES - The present invention pertains to novel enaminoketones containing a CF | 2015-01-15 |
20150018562 | PROCESS FOR THE PREPARATION OF PHENYL SUBSTITUTED 3 - DIFLUOROMETHYL - 1 -METHYL - 1H - PYRAZOLE - 4 - CARBOXYLIC ACID N-METHOXY- [1 -METHYL- 2 PHENYLETHYL] AMIDES - The invention relates to a process for the preparation of a compound of formula (I), wherein R | 2015-01-15 |
20150018563 | Surfactants and Solvents Containing Diels-Alder Adducts - Surfactants and solvents containing derivatized adducts formed from Diels-Alder reactions of terpenes and unsaturated carboxylic acids or their derivatives are disclosed. Processes for making and derivatizing the Diels-Alder adducts are also disclosed. | 2015-01-15 |
20150018564 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME - The present invention provides a new amide compound and salt thereof that is capable of inhibiting biofilm formation or removing deposited biofilms. The present invention also provides a biofilm formation inhibitor or a biofilm remover containing the amide compound or salt thereof as an active ingredient. | 2015-01-15 |
20150018565 | METHOD OF PREPARING EZETIMIBE - A method of preparing ezetimibe. The method includes converting a compound of formula (II) to a compound of formula (III) as shown below: | 2015-01-15 |
20150018566 | TUBULIN BINDING AGENTS - The invention provides combretastatin A-4 like compounds that are modified to have enhanced tubulin binding activity and in some embodiments the ability to promote accumulation in the vasculature undergoing angiogenesis (homing activity). The compounds are based on the combretastatin A-4 skeletal structure having a tubulin-binding pharmacophore comprising two fused rings (A and B rings) in which the B ring is substituted with (a) an aromatic ring structure (C ring) and (b) a second substituent/functional group that comes off the B ring. The aromatic ring structure is typically a six membered ring phenolic or aniline structure, or may also be a fused ring structure such as a substituted or unsubstituted naphthalene. The second substituent on the B ring may for example be a substituent which has been found to provide enhanced tubulin binding activity (for example a carbonyl group), or may be a substituent that facilitates functionalisation of the B ring (for example an hydroxyl or amine group), or it may be a binding agent for a target that is preferentially expressed on vasculature undergoing angiogenesis, and not expressed on quiescent vasculature. | 2015-01-15 |
20150018567 | Cyclohexenone Compositions and Process for Making Thereof - Provided herein are processes of preparing cyclohexenone compounds useful for cancer treatments and/or diseases. | 2015-01-15 |
20150018568 | PROCESS FOR PREPARATION OF DRONEDARONE BY THE USE OF DIBUTYLAMINOPROPANOL REAGENT - The invention relates to a novel process for preparation of dronedarone of formula (I) and pharmaceutically acceptable salts thereof, characterized in that a compound of formula (II)—where L is leaving group—is reacted with compound of formula (III) and the obtained product is isolated and, if desired, converted into a pharmaceutically acceptable salt thereof. | 2015-01-15 |
20150018569 | METHOD FOR PREPARING A HERBICIDAL COMPOUND - The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition. | 2015-01-15 |
20150018570 | LIPID COMPOSITIONS WITH HIGH DHA CONTENT - The invention provides lipid compositions comprising phospholipids having a high docosahexaenoic acid (DHA) content, which compositions are preferably extracted from natural sources. The lipid compositions are excellent sources of highly bioavailable DHA and they can be used in oral delivery vehicles, dietary supplements, functional foods, and the like. | 2015-01-15 |
20150018571 | ENZYMES AND METHODS FOR PRODUCING OMEGA-3 FATTY ACIDS - The present invention relates generally to the field of recombinant fatty acid synthesis, particularly in transgenic plants. The application describes genes involved in fatty acid synthesis and provides methods and vectors for the manipulation of fatty acid composition of plant oils. In particular, the invention provides constructs for achieving the integration of multiple heterologous genes involved in fatty acid synthesis into the plant genome, such that the resulting plants produce altered levels of polyunsaturated fatty acids. Also described are methods for enhancing the expression of fatty acid biosynthesis enzymes by co-expressing a silencing suppressor within the plant storage organ. | 2015-01-15 |
20150018572 | Solid Acid Catalyst, Method of Manufacturing the Same and Method of Manufacturing Fatty Acid Alkyl Ester Using the Same - The purpose of the present invention is to solve various problems with fatty acid alkyl ester methods using conventional homogenous-phase catalysts, and to provide a solid acid catalyst for fatty acid alkyl ester manufacturing that can be used to manufacture high-quality fatty acid alkyl esters and high-purity glycerin from various oils at low cost and with high yield. The present invention is a solid acid catalyst produced by supporting an oxide (B) of a metal element of at least one type selected from group VIb on the periodic table as the primary active constituent, an oxide or a sulfide (C) of a metal element of at least one type selected from the group consisting of manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc (Zn), gallium (Ga), and tin (Sn) as a promoter, and an oxide (D) of a non-metal element of at least one type selected from the group consisting of boron (B) and silicon (Si) as a catalyst stabilizer, on an inorganic porous carrier (A) such as silica, alumina, titania, magnesia, and zirconia, and applying heat treatment at 400-750° C. | 2015-01-15 |
20150018573 | Process for producing renewable bioproducts from various feedstocks - The present invention describes a method for production of a class of renewable specialty chemicals that may be used for a variety of purposes including as a solvent in the semiconductor industry and as a reagent for commercial chemical production. The precursor compound, PHA, can be produced using various feedstocks such as waste water treatment plant biosolids, distiller's grains and agricultural residual biomass (e.g., corn stover and rice straw). The production of specialty chemicals in tandem with energy production can serve to aid the overall economics of renewable feedstock energy production. | 2015-01-15 |
20150018574 | METATHESIS OF OLEFINS USING RUTHENIUM BASED CATALYTIC COMPLEXES - A self-metathesis process for the production of unsaturated dicarboxylic fatty diacids and/or unsaturated dicarboxylic fatty diesters, wherein unsaturated carboxylic fatty acids and/or esters of unsaturated carboxylic fatty acids are reacted in the presence of at least one defined ruthenium based catalyst compound. A catalyst enhancer compound selected from a sacrificial catalyst or a non-catalyst enhancer may also be used. The process exhibits improved reaction times and/or the catalyst can be used at very low concentrations. | 2015-01-15 |
20150018575 | HIGHLY SEGREGATED JET MIXER FOR PHOSGENATION OF AMINES - Embodiments of the present invention provide a mixing conduit ( | 2015-01-15 |
20150018576 | METHOD AND DEVICE FOR THE HYDROFORMYLATION OF ISOBUTENE AND FOR THE SEPARATION OF THE PRODUCT MIXTURE - The invention relates to a method for producing a product mixture ( | 2015-01-15 |
20150018577 | Process for Preparing N-(4-Cyclohexyl-3-trifluoromethyl-benzyloxy)-acetimidic Acid Ethyl Ester - This invention relates to novel processes for synthesizing N-(4-cyclohexyl-3-trifluoromethyl-benzyloxy)-acetimidic acid ethyl ester and to the compound of formula I below and other intermediates that are used in such processes. | 2015-01-15 |
20150018578 | PROCESS FOR PREPARATION OF FINGOLIMOD - The present invention provides a process for preparation of fingolimod, a compound of Formula I or a pharmaceutically acceptable salt thereof, free of regioisomeric impurity compound of Formula IA | 2015-01-15 |
20150018579 | SYNTHESIS OF HIGH PURITY DMT-C3-DISULFIDE PHOSPHORAMIDITE - The 5′ and 3′-thiol modified oligonucleotides are attractive tools with a vast number of potential applications in the field of nucleic acid chemistry. There is a strong interest in developing new disulfide compounds or to optimize synthesis of existing disulfide modifiers, which are efficient in generating the 3′- or 5′-end reactive thiol group. Various synthetic protocols have been employed to synthesize pure 3-((3-(bis(4-dimethoxytrityl)propyl)di-sulfanyl)propyl 2-cyanoethyl diisopropylphosphoramidite (compound 2) starting from 3-(dimethoxytrityl)propyl)disulfanyl)pro-pan-1-ol, (compound 1). Herein, we describe an efficient, reproducible synthetic and purification protocol for target compound 2 from the compound 1. It is noteworthy that our reaction conditions were reproducible even at multi-gram scale (27 g) with a purity level as achieved in a small scale. | 2015-01-15 |
20150018580 | SEPARATION METHOD OF ACETOPHENONE AND A-METHYLBENZLY ALCOHOL - A method of inclusive separation of acetophenone and α-methylbenzyl alcohol is provided. According to the different binding ability of Cyclodextrin (CDs) with acetophenone and α-methylbenzyl alcohol, selective separation in mild condition can be possible. This has the advantages of mild separation conditions, high separation efficiency, simplicity, reuse ability of separation media, energy conservation and environmental protection, etc. | 2015-01-15 |
20150018581 | Simultaneous Production of Base Oil and Fuel Components from Renewable Feedstock - The present invention provides a method for simultaneous production of components suitable for production of base oil and fuel components. In the method a feedstock comprising fatty acids and/or fatty acid esters is entered into a reaction zone and subjected to a ketonisation reaction in the presence of a dual catalyst system. This system is configured to perform a ketonisation reaction and a hydrotreatment reaction, under hydrogen pressure. Subsequently ketones are obtained. | 2015-01-15 |
20150018582 | DIRECT DIMETHYL ETHER SYNTHESIS FROM SYNTHESIS GAS - The invention concerns processes for preparing dimethyl ether from synthesis gas, comprising a synthesis step, wherein synthesis gas comprising hydrogen and carbon monoxide is converted into dimethyl ether and carbon dioxide, and a separation step, wherein unconverted synthesis gas is separated from carbon dioxide, wherein unconverted synthesis gas is separated from carbon dioxide by a membrane. | 2015-01-15 |
20150018583 | Process for Producing Phenol - In a process for producing phenol, benzene is reacted with a source of hydrogen containing methane in the presence of a hydroalkylation catalyst under conditions effective to produce a hydroalkylation reaction effluent comprising cyclohexylbenzene, benzene, hydrogen, and methane. A first stream comprising hydrogen, methane, and benzene is removed from the hydroalkylation reaction effluent and the first stream is washed with a second stream containing cyclohexylbenzene to produce a benzene-depleted hydrogen stream containing hydrogen and methane and a wash stream containing cyclohexylbenzene and benzene. | 2015-01-15 |
20150018584 | Methods and Systems for Saccharification of Biomass - Provided are methods and compositions for high yields while using reduced enzyme loads in saccharification and fermentation processes. These methods increase the efficiency of enzymes and result in improved yields and composition of saccharification and fermentation end products. | 2015-01-15 |
20150018585 | METAL POWDERDOUS CATALYST COMPRISING A COCRMO-ALLOY - The present invention is related to a new metal powder catalytic system (catalyst) comprising a cobalt/chrome-alloy as a carrier, its production and its use in hydrogenation processes. | 2015-01-15 |
20150018586 | METHOD FOR PRODUCING MIXTURE OF FLUOROALKYL IODIDES - The present invention provides a novel method for producing a mixture of fluoroalkyl iodides with high production efficiency, the method enabling the production of a desired fluoroalkyl iodide with high selectivity. Specifically, the present invention provides a method for producing a mixture of fluoroalkyl iodides represented by formula (I): | 2015-01-15 |
20150018587 | PROCESSES FOR ISOLATING FLUORINATED PRODUCTS - Useful processes for isolating the fluorinated products formed by reaction with 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride (Fluolead) are disclosed. The processes comprise the conversion of the byproduct (formula I) to sulfinate ester (formula V), and to sulfonate eater (formula VI), and then to the water-soluble sulfonate salt (formula IV) in the presence of the fluorinated products. | 2015-01-15 |
20150018588 | Method for Production of Hydrocarbons by Increasing Hydrocarbon Chain Length - The present invention provides a method for increasing hydrocarbon chain length. The method comprises providing a feedstock comprising fatty acids and/or fatty acid esters with hydrocarbon chain length below C | 2015-01-15 |
20150018589 | Manufacture of Butadiene from Ethylene - A method of producing butadiene includes: (1) dimerizing ethylene to butene followed by (2) oxidatively dehydrogenating the butene to butadiene and (3) recovering the butadiene by (i) absorbing the product with a hydrocarbon absorber oil and (ii) stripping a crude product stream from the absorber oil. The absorber oil is selected so as to be effective to sequester ethylene dimerization-derived impurities from the system. | 2015-01-15 |
20150018590 | CATALYST FOR CONVERSION OF HYDROCARBONS, PROCESS OF MAKING AND PROCESS OF USING THEREOF - GE ZEOLITE - In an embodiment a catalyst comprises a medium or large pore zeolite having germanium incorporated into the zeolite framework. The zeolite can have a pore structure that is one dimensional, two dimensional or three dimensional. A metal selected from Group 10 can be deposited on the zeolite. In an embodiment, a process for synthesizing the zeolite comprises preparing a medium pore zeolite containing germanium in the framework of the zeolite and calcining the zeolite. In an embodiment, the catalyst can be used in a process for the conversion of hydrocarbons comprising contacting a hydrocarbon stream containing alkanes, olefins, or mixtures thereof having 2 to 12 carbon atoms per molecule with the catalyst and recovering the product. | 2015-01-15 |
20150018591 | Method of Converting Oxygenates to Olefins - A method of converting an oxygenate comprising feedstock to olefins comprising: feeding an oxygenate comprising feedstock into a reactor containing an oxygenate to olefins conversion catalyst; contacting the feedstock with the catalyst at oxygenate conversion conditions to produce olefins; removing an effluent comprising the olefins from the reactor; passing the effluent through a compression section to form a compressed effluent; and adding methane to the compression section. | 2015-01-15 |
20150018592 | DIRECT SYNTHESIS OF DME AT EQUILIBRIUM - The invention relates to a process for production of DME ( | 2015-01-15 |
20150018593 | Catalyst, Process For The Preparation Of Said Catalyst And Use Of Said Catalyst In A Process And In A Device For The Preparation Of Olefins - The present invention relates to a catalyst characterized in that it comprises a) at least one metal compound selected from a group consisting of metal carbide, -nitride, -silicide, -phosphide and -sulfide or mixtures thereof, wherein the metal is selected from a group consisting of molybdenum, tungsten, tantalum, vanadium, titanium, niobium, lanthanum and chromium, and b) at least one non-Brønsted-acidic binder selected from a group consisting of AlPO | 2015-01-15 |
20150018594 | CLAY/POLYMER BLEND AS HIGH PH OR IONIC LIQUID BARRIER - A composition capable of increased impermeability against the passage of ionic liquids therethrough can include a clay mixed with an anionic and cationic polymer. Such compositions can be provided in geosynthetic liners to provide a hydraulic barrier in aggressive leachate environments. | 2015-01-15 |
20150018595 | TREATMENT SYSTEM, CONTROL DEVICE AND TREATMENT METHOD - According to an embodiment, a treatment system includes a plurality of first radiators, a plurality of detectors, a determiner, and a controller. Each of the first radiators irradiates a radioactive beam to a subject. Each of the detectors detects a radioactive beam transmitted through the subject and generates an image based on the detected radioactive beam. The determiner determines whether an object in the subject is included in a first region using a given image that is one of the images. The controller controls the first radiators so that, when the object is not included in the first region, a smaller amount of radioactive beams is irradiated per unit time than when the object is included in the first region. | 2015-01-15 |
20150018596 | SYSTEM FOR PLANNING RADIATION TREATMENT THERAPY - A system for planning radiation treatment therapy is provided. An optical sensor device is implanted within or in close proximity to a risk region within the patient during a radiation delivery. The sensor device optically monitors the orientation of the risk region, and the radiation dosage received by the risk region, during the radiation delivery. That information may be used as appropriate to modify an on-going radiation delivery plan in real time while the plan is being implemented. | 2015-01-15 |
20150018597 | KIT AND DEVICES FOR ORGAN PERFUSION - The present invention provides a kit for the delivery a therapeutic agent to an organ blood flow and the removal of the excess of said therapeutic agent from said organ blood flow, said kit comprises: (a) the therapeutic agent, (b) a first retrievable medical device ( | 2015-01-15 |
20150018598 | NEUROSTIMULATION PATCH - A neurostimulation patch is affixed to a patient's skin (e.g., via a medical skin adhesive) and provides stimulation energy for an implanted lead. The patch may be used for SCS trials or other applications where is it desirable to avoid implanting a stimulation device within a patient. Circuitry in the patch generates stimulation signals and couples these signals to the implanted lead. The signals may be coupled to the lead via a direct physical connection or via a wireless connection. In some embodiments, the neurostimulation patch is configured in a manner that enables the patch to be placed immediately above the puncture site where an associated percutaneous lead passes through a patient's skin, thereby protecting the puncture site and facilitating secure routing of the lead. | 2015-01-15 |
20150018599 | EYE-WEAR BORNE ELECTROMAGNETIC RADIATION REFRACTIVE THERAPY - An eye-wear borne electromagnetic radiation refractive therapy system can comprise an electromagnetic radiation source comprising a ring of LEDs that directs one of its on axis or off axis electromagnetic radiation to a desired peripheral retina area of a wearer's eye; a power source for powering the LEDs, an antenna for receiving signals and a processor for controlling the LEDs; wherein the electromagnetic radiation source includes spectral characteristics similar to outdoor light. | 2015-01-15 |
20150018600 | ENDOVASCULAR VENTRICULAR ASSIST DEVICE, USING THE MATHEMATICAL OBJECTIVE & PRINCIPAL OF SUPERPOSITION - This embodiment suggests new approach for Endovascular Ventricular Assist Device, using the mathematical objective & principle of superposition allow design and calculation of the body response to VAD pump located in the Aorta. This new approach allows minimal invasive Endovascular VAD that result in similar relief to the heart as partial VAD. Using special power transfer technique will allow wireless power transformation into the aorta. This methods and technique should dramatic reduce VAD barrier | 2015-01-15 |
20150018601 | MOTION SICKNESS DEVICE - An electrically powered device ( | 2015-01-15 |
20150018602 | SYSTEMS, METHODS, AND IMPLANTS FOR TREATING PROLAPSE OR INCONTINENCE - Described are pelvic implants, systems including the implant and a delivery tool, and methods for the treatment of incontinence or prolapse. The implant has an expansion member associated with a support portion and a tensioning member along an extension portion of the implant. Systems and methods for treating incontinence or prolapse that include a composition having non-absorbable fibers of different sizes that can be applied to and set on an implant are also provided. | 2015-01-15 |
20150018603 | MALE URETHRAL PROSTHESIS WITH TENSIONING MEMBER - The present invention provides a urethral prosthesis including a first and a second arm that join to form a junction, and a stem that is also joined to the junction. The junction is adapted to exert sufficient pressure on a portion of a patient's urethra to prevent unintentional voiding of the patient's bladder. However, upon exerting a tension force on the stem, the pressure exerted by the junction is reduced such that the patient's bladder may be intentionally voided. | 2015-01-15 |
20150018605 | EMBRYO CULTURE METHODS AND MEDIA - Improved methods of culturing embryos in media having amounts of lactate that have not previously been recognized as beneficial for embryo development. Also, compositions, devices and kits related to the same. | 2015-01-15 |
20150018606 | CATHETER ASSEMBLY - The catheter assembly includes a catheter having a catheter body, and a curved stylet that is constituted of a linear body of higher rigidity than the catheter body and is inserted into the catheter, the catheter assembly being assembled by inserting the curved stylet into the catheter. The curved stylet has a curved section, a part of which is curved. A deformation section that has been deformed in a curved manner along the curved shape of the curved section is formed on the catheter body at a portion where the curved section is located in the assembled state. The catheter assembly is so configured that, when the catheter is inserted into the urethral lumen in the assembled state, the deformation section curves a portion of the urethral lumen that faces the deformation section. | 2015-01-15 |
20150018607 | HEART CORRECTION NET - A heart correction net according to the present invention is attached to an exterior of a heart. The heart correction net includes a first area that is a partial area included in a right ventricle side area of an entire area surrounding exteriors of ventricles; and a second area that is an area surrounding the first area in the right ventricle side area and a left ventricle side area. The first area in the heart correction net is configured to provide a lower contact pressure against a heart during a cardiac diastole than the second area. | 2015-01-15 |
20150018611 | Self-Illuminating CMOS Imaging Package - A microelectronics chip contains an integrated CMOS imaging sensor integrated with a LED die. Circuitry is established on the chip for a shared power arrangement. | 2015-01-15 |
20150018612 | MEDICAL DEVICE, MEDICAL SYSTEM, AND PROGRAM - Provided is a medical device including a plurality of storage units each configured to store a different medicine, and a medicine discharge unit configured to selectively discharge at least one of a first medicine and a second medicine, each of which is stored in the plurality of storage units, when the medical device reaches a periphery of a predetermined site of an intracorporeal site of a subject. | 2015-01-15 |
20150018613 | 3D SCANNER WITH STEAM AUTOCLAVABLE TIP CONTAINING A HEATED OPTICAL ELEMENT - A 3D scanner for recording topographic characteristics of a surface of at least part of a body orifice, where the 3D scanner includes a main body having a mounting portion; a tip which can be mounted onto and un-mounted from the mounting portion, where the tip is configured for being brought into proximity of the body orifice surface when recording the topographic characteristics such that at least one optical element of the tip is at least partly exposed to the environment in the body orifice during the recording; and a heater for heating the optical element, where the heat is provided by way of thermal conduction; where the tip can be sterilized in a steam autoclave when un-mounted from the main body of the 3D scanner such that it subsequently can be reused. | 2015-01-15 |
20150018614 | Apparatus and method for controlling movement of a capsule endoscope in digestive tract of a human body - A system for controlling movement of a capsule endoscope in a human GI track is disclosed. The system comprises a magnetic dipole for placement in human GI track, an external magnet in a sphere shape generating dipole magnetic field and applying external translational and or rotational magnetic field force to the capsule endoscope, and a control system for moving the external magnet to manipulate the object along the variable axis in a desired direction of movement. | 2015-01-15 |
20150018615 | Apparatus and method for controlling movement of a capsule endoscope in digestive tract of a human body - System and method to provide a suspended capsule endoscope at a liquid gas interface is described. The capsule comprises a permanent magnetic dipole and has a density greater than the density of the liquid. An sphere-shaped external magnet is used to suspend and control the movement of the capsule endoscope at the liquid/gas interface. The capsule endoscope can translate along variable axes, rotate and tilt, according to the movement of the external magnet. The external magnet performs a translation and rotation simultaneously to keep the capsule endoscope still and anchored at the same position of the liquid/gas interface. The external magnet adjusts its distance to the liquid/gas interface during the rotation in order to apply a constant magnetic field force to the capsule endoscope. | 2015-01-15 |
20150018616 | MEDICAL TREATMENT INSTRUMENT - A medical treatment instrument includes a tube-shaped elongated main body; and an insertion guide part mounted to a distal end of the elongated main body. The insertion guide part includes a frame body mounted to a distal portion of the elongated main body; and a flexible bridge portion which is disposed so as to bridge points of an end edge of the frame body, the flexible bridge portion including a linear body or band-shaped body projecting in a distal direction beyond the elongated main body. | 2015-01-15 |
20150018617 | STEREOSCOPIC ENDOSCOPE - A stereoscopic endoscope includes an insertion portion, an objective optical system provided at a distal end portion of the insertion portion, an objective optical system provided at the distal end portion, a first opening portion provided a predetermined distance apart from an optical axis center of the objective optical system and configured to deliver fluid to the objective optical system, and a second opening portion provided a distance equivalent to the predetermined distance apart from an optical axis center of the objective optical system and configured to deliver the fluid in a supply direction same as a supply direction of the first opening portion to the objective optical system. | 2015-01-15 |
20150018618 | STEREOSCOPIC ENDSCOPE SYSTEM - To simultaneously observe not only a principal part but also a surrounding wide range, the present invention provides a stereoscopic endoscope system including an endoscope including a plurality of image capturing units which photograph a subject to acquire images at a leading edge of a long narrow insertion unit insertable into the subject, an image processing apparatus that processes the images obtained by the image capturing units in the endoscope | 2015-01-15 |
20150018619 | SPACE-SAVING FLAT INTERCONNECTION - Apparatus, consisting of an integrated circuit (IC) die, and a circuit. The IC die includes a semiconductor substrate having a substrate plane face and a substrate edge, an imaging array formed on the substrate plane face, and a plurality of array pads mounted on the substrate plane face and connected to the imaging array. The circuit includes a circuit substrate having a circuit face and a circuit edge butted to the substrate edge, a plurality of circuit pads mounted on the circuit face, and a plurality of traces mounted on the circuit face and connected to the circuit pads. The apparatus further includes a plurality of connectors coupling the array pads to the circuit pads. | 2015-01-15 |
20150018620 | INFLATABLE MEMBER FOR AN ENDOSCOPE SHEATH - Apparatus and methods for attaching and forming enclosed inflatable members on an endoscope assembly with a disposable sheath are disclosed. In one embodiment, an apparatus includes a flexible and resilient cuff member that is positioned on the outer surface of the disposable sheath and sealably and fixedly bonded to the sheath cover material at the cuff edges to form an annular space capable of being inflated. The inflatable member formed thereby is inflated through a lumen internal to the sheath that has an opening into the interior annular space. The inflatable member may be inflated to exert a longitudinal force on the insertion tube, thereby moving the endoscope assembly along a body passage. Alternately, a sheath may include a plurality of inflatable cuffs that may be inflated to create an isolated space therebetween within the body passage. | 2015-01-15 |
20150018621 | HAND-HELD EAR VACUUM WITH CAMERA AND VIDEO DISPLAY - An ear speculum that includes a body having an ear-contacting tip with an opening; a light providing member; a viewing member; and a vacuum intake port, wherein the members and intake port are provided within the ear speculum with the vacuum intake port occupying a larger portion of the of the cross-sectional area of the ear speculum opening than the light providing or viewing members to facilitate removal of material from an ear canal. Also, an otoscope that includes a head; an ear speculum as described herein in operative association with the head; an image detector in image communication with the viewing member; a suction source in vacuum communication with the vacuum intake port; and a light source in illumination communication with the light providing member. Also, a system and method for removing material or debris from an ear canal using the otoscope described herein. | 2015-01-15 |
20150018622 | SURGICAL VISUALIZATION SYSTEMS - A surgical device includes one or more cameras integrated therein. The view of each of the one or more cameras can be integrated together and provided to a surgeon display and/or an assistant display. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the images generated by the one or more cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as at least partially transparent. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices. | 2015-01-15 |
20150018623 | Surgical Access Systems and Methods - A method for retracting tissue in a surgical procedure includes inserting a first blade of a retractor system into an incision in a body of a patient. The retractor system includes a first articulating arm and a second articulating arm. The first articulating arm is coupled to a retractor assembly blade. The retractor assembly blade has a handle portion and the first blade. The second articulating arm is coupled to a bracket securing a second blade. The method includes retracting tissue using the first blade, inserting the second blade into the incision in the body of the patient and retracting tissue using the second blade. | 2015-01-15 |
20150018624 | SURGICAL RETRACTOR - The invention relates to a surgical retractor, particularly for the retraction of a separated sternum, with a holding device and two spreader arms, wherein the spreader arms are mounted with one end on the holding device, at a distance from each other that is adjustable in a spreading plane, and at least two retaining elements for retention of bone material, for example of the separated sternum, are arranged on each of the spreader arms. To develop this retractor for sternotomy in such a way as to permit gentler opening of the separated sternum, it is proposed that at least one of the retaining elements is mounted such that its position can be modified in the retraction direction with respect to that end of the spreader arm mounted on the holding device. | 2015-01-15 |
20150018625 | TISSUE RETRACTOR - A surgical site retractor is configured to retract tissue, such as in an intercostal procedure. The retractor may be formed from non-radiopaque material for improved monitoring via x-ray imaging. The retractor may have a rigid retractor and a soft tissue retractor, where the rigid retractor has a plurality of legs and the soft tissue retractor extends between the legs to prevent soft tissue from extending between said legs. The retractor may have a bendable arm with an implement holder, such as distal cuff or clip adapted to resiliently hold an implement such as a tube of an elongated port-access device. A method involves partly installing the surgical site retractor, expanding the surgical site retractor, deploying the surgical implement from outside the body through the incision and into the patient, resiliently capturing the implement with the holder of the arm, and bending the arm to hold the implement in a desired position. | 2015-01-15 |
20150018626 | ACCESS SEALING APPARATUS AND METHOD - A surgical access device includes a seal housing and a roller disposed in the housing and defining a working channel. The roller may be stationary or moveable within the seal housing to form both a zero seal in the absence of an instrument, and an instrument seal in the presence of an instrument. Rotation of the roller is contemplated and low-friction surfaces are discussed to reduce instrument insertion forces. Multiple rollers, wiper elements, low-friction braid, pivoting elements and idler rollers are contemplated. The rollers will typically be formed of a gel material in order to facilitate the desired compliance, stretchability and elongation desired. | 2015-01-15 |
20150018627 | ILLUMINATED AND MODULAR SOFT TISSUE RETRACTOR - A surgical retractor for illuminating a surgical field includes an ergonomic handle, a retractor blade coupled with the handle, a quick release mechanism, and an illuminator blade. The retractor blade is adapted to engage and retract tissue, and the quick release mechanism is adapted to couple the handle with the retractor blade. The illuminator blade acts as a waveguide to transmit light by total internal reflection. Light is extracted from the illuminator to illuminate the surgical field. The retractor blade is releasable from the handle without requiring uncoupling of the illuminator blade from the handle and also without requiring optical uncoupling of the illuminator blade from a light source. The retractor may also be adapted to evacuate smoke from the surgical field. | 2015-01-15 |
20150018628 | Surgical Access System and Methods - A method for retracting tissue in a surgical procedure includes inserting a first blade of a retractor system into an incision in a body of a patient. The retractor system includes a first articulating arm and a second articulating arm. The first articulating arm is coupled to a retractor assembly blade. The retractor assembly blade has a handle portion and the first blade. The second articulating arm is coupled to a bracket securing a second blade. The method includes retracting tissue using the first blade, inserting the second blade into the incision in the body of the patient and retracting tissue using the second blade. | 2015-01-15 |
20150018629 | Eye Surgical Lighting Unit - The invention relates to an eye surgical lighting unit for lighting internal ocular tissue. The lighting unit comprises a fiber having a proximal end and a distal end, for guiding a light beam to the distal end. The lighting unit also comprises a manual unit, provided with a cannula and a handle having an internal passage positioned in line with the cannula. The fiber is adjustable between an intraocular operational position in which the fiber extends through the internal passage of the handle and through the cannula, and a chandelier operational position in which the fiber is uncoupled from the manual unit. | 2015-01-15 |
20150018630 | SYSTEMS AND METHODS FOR CREATING COMPREHENSIVE AND PERSONALIZED BRAIN HEALTH PROGRAMS - Systems, methods and computer-readable storage media for generating comprehensive and personalized brain health programs are described. The brain health programs may be configured to improve the brain health of a patient, including improving patient cognitive function and/or increasing hippocampal volume. The brain health programs may use various interventions, including, without limitation, exercises, activities, habits, and diet, that are directed toward certain aspects of a patient's brain and/or brain function, such as memory abilities or increasing the size of the hippocampus or other parts of the brain. | 2015-01-15 |
20150018631 | Apparatus and Method for Measuring Physiological Signals - A measuring unit has at least one first signal-measuring end and at least one second signal-measuring end. The first signal-measuring end and the second signal-measuring end contact at least two symmetrical portions of a living being to obtain at least one first pulse signal and at least one second pulse signal of the two symmetrical portions, respectively. A signal-analyzing unit is coupled to the measuring unit. The signal-analyzing unit obtains at least one physiological data based on the first pulse signal and the second pulse signal, respectively, further to determine a physiological condition of the living being according to the physiological data. | 2015-01-15 |
20150018632 | System and Method For Monitoring Cardiac Blood Flow Balance Between The Right and Left Heart Chambers - A system for measuring of cardiac blood flow balance parameter between the right chamber of the heart and the left chamber of the heart includes a sensor device for measuring one of blood pressure and blood flow rate and blood constituent concentration of a patient so as to generate an arterial pulse signal. A processing unit is responsive to the arterial pulse signal for generating a full arterial pulse signal, an arterio-venous pulse signal, and a balance parameter. A computational device is responsive to the balance parameter for further generating a set of physiological parameters. A display station device is responsive to the set of physiological parameters from the computational device for displaying meaningful information. | 2015-01-15 |
20150018633 | Unified Platform for Monitoring and Control of Blood Glucose Levels in Diabetic Patients - A flexible system capable of utilizing data from different monitoring techniques and capable of providing assistance to patients with diabetes at several scalable levels, ranging from advice about long-term trends and prognosis to real-time automated closed-loop control (artificial pancreas). These scalable monitoring and treatment strategies are delivered by a unified system called the Diabetes Assistant (DiAs) platform. The system provides a foundation for implementation of various monitoring, advisory, and automated diabetes treatment algorithms or methods. The DiAs recommendations are tailored to the specifics of an individual patient, and to the patient risk assessment at any given moment. | 2015-01-15 |
20150018634 | SYSTEMS AND METHODS FOR DETECTING CEREBROSPINAL-FLUID PULSATION USING AN IMPLANTABLE ELECTRICAL STIMULATION DEVICE - An electrical stimulation lead assembly includes a lead body having a distal end portion, a proximal end portion, and a longitudinal length. Electrodes are disposed along the distal end portion of the lead body; terminals disposed along the proximal end portion of the lead body; and stimulation conductors couple the terminals to the electrodes. A cerebrospinal-fluid-pulsation detection assembly includes a sensor disposed along the distal end portion of the lead body. The sensor detects pulses of cerebrospinal fluid within a subarachnoid space of a patient and transforms the detected cerebrospinal-fluid pulses into sensor signals. A sensor processor receives the sensor signals from the sensor, processes the received sensor signals to cerebrospinal-fluid pulsation data (“CSF-pulsation data”), and estimates a patient blood-flow condition based on the CSF-pulsation data. A sensor control pathway couples the sensor to the sensor processor. | 2015-01-15 |
20150018635 | MULTIFACTORIAL TELEHEALTH CARE PREGNANCY AND BIRTH MONITORING - A system for monitoring a fetus in a pregnant woman, and/or the maternal health risk for pregnancies complicated by such as pre-eclampsia and hypertensive disorders is configured to be worn by the pregnant woman, preferably so as to allow monitoring during daily life, e.g. in the form of an adhesive patch. The unit has a sound sensor, e.g. a microphone or accelerometer, to be positioned on the skin of the abdominal area so as to detect a vascular sound from umbilical arteries of the fetus or from the uterine arteries of the pregnant woman. The sound sensor is functionally connected to a processing unit which executes a processing algorithm on the captured vascular sound and extracts a signal parameter accordingly. The processing unit then communicates the signal parameter, e.g. using an audio signal, a visual display or by means of a wired or a wireless data signal. | 2015-01-15 |
20150018636 | Reduction of Physiological Metric Error Due to Inertial Cadence - The heart rate monitor disclosed herein removes a step rate component from a measured heart rate by using one or more filtering techniques when the step rate is close to the heart rate. In general, a difference between the step rate and the heart rate is determined, and the step rate is filtered from the heart rate based on a function of the difference. | 2015-01-15 |
20150018637 | METHOD AND SYSTEM FOR OPTICAL BLOOD PRESSURE MONITORING - An apparatus, methods and a system for cuffless blood pressure monitoring are provided. The system includes an optical BCG sensor, a PPG sensor, a transceiver and a signal processing device. The BCG sensor optically couples to the subject, acquires BCG signals from the subject, and optically transmits the subject's BCG signals. The PPG sensor optically couples to the subject for acquiring PPG signals from the subject and optically transmits the acquired subject's PPG signals. The transceiver is coupled to the BCG sensor and the PPG sensor for receiving the BCG signals and the PPG signals and generating a BCG electronic signal from the subject's BCG signals and a PPG electronic signal from the subject's PPG signals. And the signal processing device is coupled to the transceiver for receiving the BCG electronic signal and the PPG electronic signal and for monitoring the subject's blood pressure in response to predetermined BCG indicia of the BCG electronic signal and predetermined PPG indicia of the PPG electronic signal. | 2015-01-15 |
20150018638 | APPARATUS AND METHOD FOR NON-INVASIVE MEASUREMENT OF BLOOD PARAMETERS - The present invention provides techniques for non-invasive measurement of blood related parameters based on NMR (nuclei) relaxation techniques carried out using a relatively low constant magnetic field in the range of 0.15 to 0.5 Tesla. A plurality of electromagnetic excitation pulse sequences having relatively low radiofrequencies are applied over a living tissue placed in the magnetic field and blood related parameters of the examined subject are determined using a plurality of nuclear spin echo signals received from the tissue in response to the applied excitation sequences, thereby allowing to improve the accuracy of the obtained signals and substantially reducing the time duration of the process. | 2015-01-15 |
20150018639 | Method and System for Providing an Integrated Analyte Sensor Insertion Device and Data Processing Unit - Method and apparatus for providing an integrated analyte sensor and data processing unit assembly is provided. | 2015-01-15 |
20150018640 | Method and Apparatus for Providing Analyte Sensor Insertion - Devices and methods for positioning a portion of a sensor at a first predetermined location, displacing the portion of the sensor from the first predetermined location to a second predetermined location, and detecting one or signals associated with an analyte level of a patient at the second predetermined location are disclosed. Also provided are systems and kits for use in analyte monitoring. | 2015-01-15 |
20150018641 | Fiber Optic Device for Sensing Analytes and Method of Making Same - A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel. | 2015-01-15 |
20150018642 | TISSUE PATHLENGTH RESOLVED NONINVASIVE ANALYZER APPARATUS AND METHOD OF USE THEREOF - An analyzer apparatus and method of use thereof is configured to dynamically interrogate a sample. For example, an analyzer using light interrogates a tissue sample using a temporal resolution system on a time scale of less than about one hundred nanoseconds. Optionally, near-infrared photons are introduced to a sample with a known illumination zone to detection zone distance allowing calculation of parameters related to photon pathlength in tissue and/or molar absorptivity of an individual or group through the use of the speed of light and/or one or more indices of refraction. Optionally, more accurate estimation of tissue properties are achieved through use of: knowledge of incident photon angle relative to skin, angularly resolved detector positions, anisotropy, skin temperature, environmental information, information related to contact pressure, blood glucose concentration history, and/or a skin layer thickness, such as that of the epidermis and dermis. | 2015-01-15 |
20150018643 | SYSTEMS, DEVICES, AND METHODS FOR ENERGY EFFICIENT ELECTRICAL DEVICE ACTIVATION - Systems, devices, and methods are provided for changing the power state of a sensor control device in an in vivo analyte monitoring system in various manners, such as through the use of external stimuli (light, magnetics) and RF transmissions. | 2015-01-15 |
20150018644 | MULTIPLEXED PATHLENGTH RESOLVED NONINVASIVE ANALYZER APPARATUS WITH NON-UNIFORM DETECTOR ARRAY AND METHOD OF USE THEREOF - A noninvasive analyzer apparatus and method of use thereof is described comprising a near-infrared source, a non-uniform detector array, and a photon transport system configured to direct photons from the source to the detector via an analyzer-sample optical interface. The non-uniform detector array provides a multitude of distinguishable optical pathlengths, couples to a plurality of optical transmission filters, couples to a plurality of light directing micro-optics, and/or couples to an array of light-emitting diodes. | 2015-01-15 |
20150018645 | DISPOSABLE CALIBRATION END-CAP FOR USE IN A DERMOSCOPE AND OTHER OPTICAL INSTRUMENTS - A disposable tubular end cap for a dermoscope for examining the skin of an animal. The end cap has one end for receiving light from and transmitting light to the dermoscope, a removable calibration target disposed at the other end having optical characteristics similar to a standard skin type, and an identifier disposed on the end cap. The identifier uniquely identifies the end cap and associates it with both data regarding light emitted from the skin of an animal and calibration data derived from the calibration target. Animal tissue may be examined to identify lesions using a plurality of wavelengths and a plurality of polarizations. | 2015-01-15 |
20150018646 | DYNAMIC SAMPLE MAPPING NONINVASIVE ANALYZER APPARATUS AND METHOD OF USE THEREOF - A noninvasive analyzer apparatus and method of use thereof is described using a sample mapping phase to establish one or more analyzer/software parameters used in a subsequent individual and/or group specific data collection phase. For example, in the sample mapping phase distance between incident and collected light is varied as a function of time for collected noninvasive spectra. Spectra collected in the sample mapping phase are analyzed to determine a physiological property of the subject, such as dermal thickness, hydration, collagen density, epidermal thickness, and/or subcutaneous fat depth. Using the physiological property or measure thereof, the analyzer is optically reconfigured for the individual to yield subsequent spectra having enhanced features for noninvasive analyte property determination. Similarly, in the mapping and/or collection phase, the incident light is varied in time in terms of any of: sample probe position, incident light solid angle, incident light angle, depth of focus, energy, and/or intensity. | 2015-01-15 |
20150018647 | METHOD AND APPARATUS FOR MONITORING A SUBJECT FOR BLOOD OXYGEN SATURATION - What is disclosed is a system and method for monitoring a subject of interest for functional blood oxygen saturation using an apparatus that can be comfortably worn by the subject around an area of exposed skin where a photoplethysmographic (PPG) signal can be registered. In one embodiment, the apparatus is a reflective or transmissive wrist-worn device with emitter/detector pairs fixed to an inner side of a band with at least two illuminators, each emitting source light at a different wavelength band. Each photodetector comprises sensors that are sensitive to a wavelength band of its respective illuminator. Each photodetector measures an intensity of sensed light emitted by a respective illuminator. The signal obtained by the sensors comprises a continuous PPG signal. The continuous PPG signal analyzed for functional blood oxygen saturation levels and communicated to a remote device. Various embodiments are disclosed. | 2015-01-15 |
20150018648 | SYSTEMS AND METHODS FOR MONITORING PATIENTS ON VENTILATION - A system for monitoring a patient on ventilation including a ventilator system, a pulse oximeter, an information processing system, and a display device. The ventilator system is configured to provide mechanical ventilation in accordance with an FiO | 2015-01-15 |
20150018649 | METHODS AND SYSTEMS FOR USING A DIFFERENTIAL LIGHT DRIVE IN A PHYSIOLOGICAL MONITOR - A physiological monitoring system may use a differential light drive to illuminate one or more light sources. A differential light drive may include applying two signals, one to each terminal of a light emitting diode or other light source, such that the illumination of the light source is controlled by the difference between the two light drive signals. In some embodiments, light emitting diodes may be turned on and off using a differential light drive without using switches and using only unipolar voltage sources. In some embodiments, light drive signals may be 180 degrees out-of-phase, and the phase shift may be used to reduce crosstalk and other electronic noise, for example by carrying the signals in a twisted pair of conductors. | 2015-01-15 |
20150018650 | PHYSIOLOGICAL MONITOR - A patient monitor has multiple sensors adapted to attach to tissue sites of a living subject. The sensors generate sensor signals that are responsive to at least two wavelengths of optical radiation after attenuation by pulsatile blood within the tissue sites. | 2015-01-15 |
20150018651 | INDICATORS FOR A SPECTROPHOTOMETRIC SYSTEM - A near-infrared spectrophotometric system (e.g., a cerebral oximeter) includes a sensor portion and a monitor portion. The monitor portion includes a processor that runs an algorithm which utilizes the amount of detected light to determine the value of the oxygen concentration (e.g., the absolute level of oxygen concentration). The monitor portion also includes a visual display that displays the determined oxygen concentration values in various formats. The monitor portion may also include an audible device (e.g., a speaker), that provides audible indications of the determined oxygen concentration values. Various visual indicators may include, for example, color-coded graphs of the determined oxygenation values to alert the system user, for example, whether one hemisphere of the brain, or one or more regions of the brain, is in danger of adverse and potentially permanent damage. Also, data may be pre-processed by selecting the most clinically concerning sensor value (e.g., the sensor with the lowest value), and displaying only that sensor value and its identification on the display screen. Alternatively, an average value of multiple sensor measurements may be displayed. This reduces screen clutter and increases the speed of interpretation by the system user. Also, all sensor values may be averaged, and the average value displayed. The determined oxygenation values may also be provided in an audible format. | 2015-01-15 |