03rd week of 2010 patent applcation highlights part 65 |
Patent application number | Title | Published |
20100017896 | Filaggrin - The present invention relates to the identification of loss-of-function mutations in the filaggrin gene and their use in diagnosing ichthyosis vulgaris and/or susceptibility to other diseases including atopic dermatitis (eczema), asthma, psoriasis and allergies (including food allergy). | 2010-01-21 |
20100017897 | PRRG4-ASSOCIATED COMPOSITIONS AND METHODS OF USE THEREOF IN METHODS OF TUMOR DIAGNOSIS - Compositions and methods for detecting PRRG4- and PRRG2 associated molecules are provided as are methods of use thereof for the detection and treatment of cancer. | 2010-01-21 |
20100017898 | THERAPEUTIC APPLICATIONS OF NONCOVALENT DIMERIZING ANTIBODIES - Compositions and methods for providing antibodies having noncovalent, self-binding properties are disclosed. Such autophilic antibodies can bind cellular receptors to promote apoptosis of target cells and enhance therapeutic efficacies in the treatment of patients with debilitating or life-threatening diseases. Representative diseases targeted by the autophilic antibodies are lymphomas, breast cancers, colon cancers, and melanomas. Autoimmune disorders, Alzheimer's disease, and other neuro-degenerative conditions, as well as graft or transplant rejection, are among other treatable conditions. | 2010-01-21 |
20100017899 | METHOD FOR THE ISOLATION OF PLURIPOTENT CELLS FROM A PRE-IMPLANTATION EMBRYO IN A CULTURE MEDIUM FREE FROM ANIMAL SERUM - The present invention provides a method of isolating a pluripotent cell from a pre-implantation embryo without isolation of the pluripotent cells from other cells, the method including propagating a whole pre-implantation embryo including one or more pluripotent cells, embedded in a feeder cell layer and cultivated in a medium substantially free of serum, and isolating a pluripotent cell from the one or more pluripotent cells. The present invention also provides pluripotent cells generated by the method and uses thereof. | 2010-01-21 |
20100017900 | Prostate Epithelial Androgen Receptor Suppresses Prostate Growth and Tumor Invasion - Described herein is the generation of the first conditional knockout AR (pes-ARKO) mice that lack AR only in prostate epithelia. Additionally demonstrated herein, through AR gain- and loss-of-function experiments, are the novel growth and differentiation roles of epithelial AR within the normal and cancerous prostate cells. | 2010-01-21 |
20100017901 | Compositions Comprising MG29 Nucleic Acids, Polypeptides, and Associated Methods of Use - Disclosed herein are compositions and methods for treatment of muscle dysfunction (including sarcopenia) and other diseases involving skeletal muscle, including age-related muscle dysfunction. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal muscle disorder, including those related to thr normal aging process. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ regulation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced. | 2010-01-21 |
20100017902 | Corn event PV-ZMGT32(nk603) and compositions and methods for detection thereof - The present invention provides a DNA construct that confers tolerance to transgenic corn plant. Also provided are assays for detecting the presence of the PV-ZMGT32(nk603) corn event based on the DNA sequence of the recombinant construct inserted into the corn genome and of genomic sequences flanking the insertion site. | 2010-01-21 |
20100017903 | SLOW-MATURING, DETERMINATE PEAS - A determinate pea plant, where peas of the pea plant have a wrinkled-seed phenotype, and where the pea plant is slow-maturing. | 2010-01-21 |
20100017904 | Genes and uses for plant improvement - Transgenic seed for crops with improved traits are provided by trait-improving recombinant DNA in the nucleus of cells of the seed where plants grown from such transgenic seed exhibit one or more improved traits as compared to a control plant. Of particular interest are transgenic plants that have increased yield. The present invention also provides recombinant DNA molecules for expression of a protein, and recombinant DNA molecules for suppression of a protein. | 2010-01-21 |
20100017905 | NUCLEOTIDE SEQUENCES MEDIATING PLANT MALE FERTILITY AND METHOD OF USING SAME - Nucleotide sequences mediating male fertility in plants are described, with DNA molecule and amino acid sequences set forth. Promoter sequences and their essential regions are also identified. The nucleotide sequences are useful in mediating male fertility in plants. In one such method, the homozygous recessive condition of male sterility causing alleles is maintained after crossing with a second plant, where the second plant contains a restoring transgene construct having a nucleotide sequence which reverses the homozygous condition. The restoring sequence is linked with a hemizygous sequence encoding a product inhibiting formation or function of male gametes. The maintainer plant produces only viable male gametes which do not contain the restoring transgene construct. Increase of the maintainer plant is also provided by self-fertilization, and selection for seed or plants which contain the construct. | 2010-01-21 |
20100017906 | NUCLEOTIDE SEQUENCES MEDIATING PLANT MALE FERTILITY AND METHOD OF USING SAME - Nucleotide sequences mediating male fertility in plants are described, with DNA molecule and amino acid sequences set forth. Promoter sequences and their essential regions are also identified. The nucleotide sequences are useful in mediating male fertility in plants. In one such method, the homozygous recessive condition of male sterility causing alleles is maintained after crossing with a second plant, where the second plant contains a restoring transgene construct having a nucleotide sequence which reverses the homozygous condition. The restoring sequence is linked with a hemizygous sequence encoding a product inhibiting formation or function of male gametes. The maintainer plant produces only viable male gametes which do not contain the restoring transgene construct. Increase of the maintainer plant is also provided by self-fertilization, and selection for seed or plants which contain the construct. | 2010-01-21 |
20100017907 | NUCLEOTIDE SEQUENCES MEDIATING PLANT MALE FERTILITY AND METHOD OF USING SAME - Nucleotide sequences mediating male fertility in plants are described, with DNA molecule and amino acid sequences set forth. Promoter sequences and their essential regions are also identified. The nucleotide sequences are useful in mediating male fertility in plants. In one such method, the homozygous recessive condition of male sterility causing alleles is maintained after crossing with a second plant, where the second plant contains a restoring transgene construct having a nucleotide sequence which reverses the homozygous condition. The restoring sequence is linked with a hemizygous sequence encoding a product inhibiting formation or function of male gametes. The maintainer plant produces only viable male gametes which do not contain the restoring transgene construct. Increase of the maintainer plant is also provided by self-fertilization, and selection for seed or plants which contain the construct. | 2010-01-21 |
20100017908 | Highly Transformable Elite Doubled Haploid Line PH17AW - A novel double haploid maize line designated PH17AW and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing double haploid maize line PH17AW with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH17AW through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the double haploid line PH17AW or a trait conversion of PH17AW with another maize line. Inbred maize lines derived from double haploid maize line PH17AW, methods for producing other inbred maize lines derived from double haploid maize line PH17AW and the inbred maize lines and their parts derived by those methods. | 2010-01-21 |
20100017909 | Nitrate transport components - This invention relates to isolated nucleic acid fragments encoding high affinity nitrate transport components. The invention also relates to the construction of recombinant DNA constructs encoding all or a portion of nitrate transport components, in sense or antisense orientation, wherein expression of the recombinant DNA construct may alter levels of the nitrate transport components in a transformed host cell. | 2010-01-21 |
20100017910 | Compositions and Methods Using RNA Interference of CDPK-Like For Control of Nematodes - The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of genes essential to establishing or maintaining nematode infestation in a plant, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target plant gene, which is a CDPK-like gene, and relates to the generation of plants that have increased resistance to parasitic nematodes. | 2010-01-21 |
20100017911 | VIRAL-BASED TRANSIENT-EXPRESSION VECTOR SYSTEM FOR TREES - Disclosed herein are viral vectors suitable for transfection into woody trees for purposes of delivering and expressing beneficial genes with increased stability. Specifically exemplified herein are vectors for transfecting citrus trees. The vectors allow for the expression of useful proteins, such as those that can protect the tree from disease. | 2010-01-21 |
20100017912 | COMPOSITIONS AND METHODS USING RNA INTERFERENCE OF CAD-LIKE GENES FOR CONTROL OF NEMATODES - The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of genes essential to establishing or maintaining nematode infestation in a plant, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target CAD-like plant gene, and relates to the generation of plants that have increased resistance to parasitic nematodes. | 2010-01-21 |
20100017913 | DISEASE RESISTANT PLANTS - The invention provides transgenic plants with resistance to infection by a root-infecting fungal plant pathogen such as | 2010-01-21 |
20100017914 | INSECTICIDAL PROTEINS - Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different | 2010-01-21 |
20100017915 | Manipulation of Plant Polysaccharide Synthases - The present invention provides compositions and methods for manipulation of plant polysaccharides and plant polysaccharide syntheses. Compositions include novel nucleotide sequences encoding polysaccharide synthases polypeptides, and biologically active variants thereof. Further provided are methods for polysaccharide manipulation using the sequences disclosed herein. One method comprises stably incorporating into the genome of a plant cell, a nucleotide sequence of the present invention operably linked to a heterologous promoter and regenerating a stably transformed plant that expresses the nucleotide sequence. | 2010-01-21 |
20100017916 | Systems for reducing biomass recalcitrance - Improved systems and methods for reducing costs and increasing yields of cellulosic ethanol including compositions of matter comprising plant biomass and cell wall-modifying enzyme polypeptides and transgenic plants expression cell wall-modifying enzyme polypeptides. | 2010-01-21 |
20100017917 | TRANSGENIC PLANTS WITH TOCOPHEROL METHYLTRANSFERASE - Disclosed is are gene sequences encoding γ-tocopherol methyltransferases from photosynthetic organisms. The enzyme γ-tocopherol methyltransferase catalyzes the methylation of γ-tocopherol to yield α-tocopherol, the most bioactive species of tocopherol. γ-tocopherol methyltransferase is believed to be involved in regulating the relative amounts of the various tocopherols present in photosynthetic organisms. By introducing a genetic construct having a γ-tocopherol methyltransferase coding sequence placed under the control of a plant promoter into a plant, transgenic plants can be made having altered γ-tocopherol methyltransferase expression, to effect dramatic changes in the tocopherol profile of the plant. Transgenic plants can be made that have α-tocopherol as the predominant tocopherol in their seeds and oils. | 2010-01-21 |
20100017918 | ARABIDOPSIS DERIVED PROMOTERS FOR REGULATION OF PLANT EXPRESSION - The invention provides a method to identify a plurality of plant promoters having specified characteristics and promoters identified by the method. Also provided are transgenic plants comprising the genes identified by the methods of the invention. | 2010-01-21 |
20100017919 | Rice Gene, GS3, Exerting Primary Control Over Grain Length and Grain Weight - The present invention relates to an isolated major gene GS3 which regulates grain weight and grain length in the rice and the cloning of said gene. The DNA sequence of GS3 gene is as shown in SEQ ID NO. 1 and is 7883 bp in length. GS3 gene comprises 5 exons and encodes 232 amino acids. It is predicted based on bioinformatics analysis that said protein contains conserved domains including a PEBP-like domain, a transmembrane domain, a cysteine-rich domain of TNFR/NGFR and a VWFC domain. cDNA sequence of said gene is as shown in SEQ ID NO. 2. By sequence alignment between three large grain species and 3 small grain species of rice, it is revealed there is only one common single nucleotide mutation in a 7.9-kb region between the two different grain-length groups. Said nucleotide mutation is located at the second exon of the GS3 gene, in which a cysteine codon (TGC) in the small-grain group is mutated to a termination codon (TGA) in the large-grain group. This mutation causes a premature termination in the large-grain group, which leads to a 178-amino acids truncation (including part of the PEBP-like domain and all the other three conserved domains). The present invention also provides methods of producing transgenic plants comprising sequences disclosed herein. | 2010-01-21 |
20100017920 | SCANNING PROBE MICROSCOPE WITH TILTED SAMPLE STAGE - A scanning probe microscope has a tilting stage on which a sample is mounted. The sample is scanned back and forth with the stage being tilted clockwise during a forward scan and counterclockwise during a reverse scan. A first surface contour of the sample is determined from the response of the probe and the tilt angle of the stage during the forward scan. A second surface contour of the sample is determined from the response of the probe and the tilt angle of the stage during the reverse scan. A final surface contour of the sample is obtained by combining the first and second surface contours. | 2010-01-21 |
20100017921 | DEVICE AND METHOD FOR THE MICROMECHANICAL POSITIONING AND HANDLING OF AN OBJECT - The invention relates to a device and a method for the micromechanical positioning and handling of an object. The aim of the invention is to provide a device and an associated method for the micromechanical positioning and handling of objects by means of which the scanning speed can be increased and the positional accuracy be improved so that real time images or video rate images (ca. 25 images per second) having a lateral and vertical resolution in the nanometer range can be achieved. According to the invention, a monolithic component, preferably made of silicon, comprises a support element, an object carrier, a plurality of guide elements and elements for transmitting the movement, the preferably piezoresistive drive elements and the preferably piezoresistive position detectors being integrated into said monolithic component; Said micromechanical positioning device can be used, for example, in scanning probe microscopy and in nanopositioning and nanomanipulation technology. | 2010-01-21 |
20100017922 | INTEGRATED SENSING PROBES, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF - Briefly described, embodiments of this disclosure include integrated sensing probes, sensing systems, methods of detecting a target compound, and the like. One exemplary integrated sensing probe, among others, includes: a substrate, a circular corrugated reflective surface, and a coaxial waveguide structure, wherein the corrugated reflective surface and the coaxial waveguide structure are disposed on the substrate, wherein the coaxial waveguide structure is positioned at the center of the circular corrugated reflective surface. | 2010-01-21 |
20100017923 | PREAMPLIFYING CANTILEVER AND APPLICATIONS THEREOF - Aspects of the invention are directed to piezoresponse force analysis of a material. A stimulus signal including a first frequency component is applied to a contact point on the material such that the stimulus signal actuates a portion of the material to experience a motion as a result of a piezoelectric effect. A resonant device is coupled to the contact point such that the resonant device experiences a resonant motion at the first frequency component in response to the motion of the material, the resonant motion having a greater displacement than a displacement of the motion of the material, and is substantially unaffected by mechanical properties of the material at the contact point. The resonant motion of the resonant device is detected and processed to produce a measurement representing the piezoresponse of the material at the contact point. | 2010-01-21 |
20100017924 | METHOD FOR USING AN ATOMIC FORCE MICROSCOPE - The present invention relates to a method of using an atomic force microscope comprising exciting natural lower and higher vibration modes of a microlever (M) placed on a sample, and analyzing the variation of one variable of a first output signal (A | 2010-01-21 |
20100017925 | PRUNUS ROOTSTOCK NAMED 'MYROCOT' - A new and distinct | 2010-01-21 |
20100017926 | Mandarin orange tree named 'GARBI' - A new and distinct triploid | 2010-01-21 |
20100017927 | Mandarin orange tree named 'SAFOR' - A new and distinct triploid | 2010-01-21 |
20100017928 | SALVIA PLANT NAMED 'SHELL DANCER' - A new and distinct | 2010-01-21 |