03rd week of 2016 patent applcation highlights part 10 |
Patent application number | Title | Published |
20160015862 | COATING FOR INTRALUMINAL EXPANDABLE CATHETER PROVIDING CONTACT TRANSFER OF DRUG MICRO-RESERVOIRS - A coating for an expandable portion of a catheter comprising a hydrophobic matrix and a dispersed phase is disclosed. The dispersed phase comprises a plurality of micro-reservoirs dispersed in the hydrophobic matrix, wherein the plurality of micro-reservoirs comprises a first active agent and a first biodegradable or bioerodable polymer. A coating formulation and a method for forming the coating are also disclosed. A catheter comprising the coating on the expandable portion and a method for treating a condition are also provided. | 2016-01-21 |
20160015863 | DEVICES WITH ANTI-THROMBOGENIC AND ANTI-MICROBIAL TREATMENT - A medical device adapted for contact with a vessel or cavity in the body including a tubular portion is provided. The device has an external surface including an external substance that is at least one of a coating or an impregnation, comprising alexidine in an amount that is both anti thrombogenically effective and anti microbially effective. The device also has an internal surface including an internal substance that is at least one of a coating or an impregnation, comprising alexidine in an amount that is both anti thrombogenically effective and anti microbially effective. | 2016-01-21 |
20160015864 | COATING COMPOSITION AND MEDICAL DEVICE - A coating composition capable of forming a drug coating layer unsusceptible to peeling in the process of delivery of a water-insoluble drug to a target tissue is provided. The coating composition contains the water-insoluble drug and a basic compound which is positively charged at physiological pH. A medical device coated with the coating composition is further provided. | 2016-01-21 |
20160015865 | METASTABLE POLYMER COMPOSITIONS FOR OPHTHALMIC IMPLANT INJECTION DEVICES - The invention relates to metastable polymer compositions, use thereof for manufacturing medical devices or medical device components having a slippery surface as well as the devices with slippery surfaces resulting from these metastable polymer compositions, in particular in the field of ophthalmic injectors. | 2016-01-21 |
20160015866 | Anti-Adhesive Barrier Membrane Using Alginate and Hyaluronic Acid for Biomedical Applications - A non-synthetic, hydrophilic, biodegradable, biocompatible polysaccharide based non-toxic anti-adhesion hydrogel barrier is disclosed herein. The barrier of the present invention is formed by constructing a unique interpenetrating, crosslinked network with a unique porosity. Furthermore, the barrier of the present invention is comprised of tunable biopolymers for controllable mechanical robustness and degradation. The barrier of the present invention effectively reduces unwanted adhesions using non-synthetic components. | 2016-01-21 |
20160015867 | RECYCLED RESIN COMPOSITIONS AND DISPOSABLE MEDICAL DEVICES MADE THEREFROM - Syringe plunger rods comprising an elongate body formed from a composition comprising one or more of virgin material, a sterilization-stable recycled resin and a biobased compositions are described. Plunger rods comprising a plurality of ribs, some of which may have a plurality of openings, are also described. The plunger rods requiring less material while maintaining sufficient structural integrity to function properly. | 2016-01-21 |
20160015868 | Drug Composition and Coating - According to the invention there is provided inter alia a medical device for delivering a therapeutic agent to a tissue, the device having a solid surfactant-free particulate coating layer applied to a surface of the device, the coating layer comprising a therapeutic agent and at least one non-polymeric organic additive which is hydrolytically stable; wherein at least a proportion of the particulate coating layer comprising the therapeutic agent and the at least one organic additive melts as a single phase at a lower temperature than the melting point of the therapeutic agent and the at least one organic additive when in pure form; wherein the therapeutic agent is paclitaxel; and wherein the therapeutic agent, when formulated in the coating layer, is stable to sterilization. | 2016-01-21 |
20160015869 | MEDICAL DEVICE AND METHOD FOR PRODUCING MEDICAL DEVICE - A medical device including a lubricating coating film (surface lubricating layer) that exerts excellent lubricity and durability is provided. The medical device includes, on a base layer, a surface lubricating layer formed from a block copolymer having a hydrophilic portion and a hydrophobic portion that has a reactive functional group. The ratio of the hydrophobic portion of the block copolymer in an outermost surface of the surface lubricating layer is 20 to 45 mol %, and the viscosity of a 1 wt % chloroform solution of the block copolymer at a temperature of 30° C. is 8 to 30 mPa·s. | 2016-01-21 |
20160015870 | Drug Composition and Coating - According to the invention there is provided inter alia a medical device for delivering a therapeutic agent to a tissue, the device having a solid surfactant-free particulate coating layer applied to a surface of the device, the coating layer comprising a therapeutic agent and at least one non-polymeric organic additive which is hydrolytically stable; wherein at least a proportion of the particulate coating layer comprising the therapeutic agent and the at least one organic additive melts as a single phase at a lower temperature than the melting point of the therapeutic agent and the at least one organic additive when in pure form; wherein the therapeutic agent is paclitaxel; and wherein the therapeutic agent, when formulated in the coating layer, is stable to sterilization. | 2016-01-21 |
20160015871 | INSTILLATION CARTRIDGE FOR VACUUM ACTUATED FLUID DELIVERY - A fluid delivery system, method, and apparatus for providing instillation therapy with a negative-pressure source is described. The apparatus includes a housing having an ambient chamber and a negative-pressure chamber fluidly isolated from each other. The apparatus also includes a moveable barrier disposed in the housing between the ambient chamber and the negative-pressure chamber. The moveable barrier is operable to move between a charge position and a discharge position in response to negative pressure. A fluid source is disposed in the negative-pressure chamber and is collapsible in response to movement of the moveable barrier to the discharge position. The apparatus also includes a fluid outlet in fluid communication with the fluid source, a negative-pressure port in fluid communication with the negative-pressure chamber and configured to be coupled to a negative-pressure source, and a vent formed in the housing and fluidly coupled to the ambient chamber. | 2016-01-21 |
20160015872 | DISPOSABLE CARTRIDGE FOR VACUUM ACTUATED FLUID DELIVERY - Systems, methods, and apparatuses for providing instillation therapy with a negative-pressure source are described. The apparatus can include a housing having a dosing chamber and a negative-pressure chamber fluidly isolated from each other. The apparatus can also include a moveable barrier disposed in the housing between the dosing chamber and the negative-pressure chamber. The housing includes a fluid inlet in fluid communication with the dosing chamber and a fluid outlet in fluid communication with the dosing chamber. The housing can also include a negative-pressure inlet in fluid communication with the negative-pressure chamber and a biasing element coupled to the moveable barrier. The biasing element is operable to move the moveable barrier between a charge position and a discharge position. | 2016-01-21 |
20160015873 | INSTILLATION CARTRIDGE AND THERAPY SYSTEM FOR NEGATIVE-PRESSURE THERAPY AND INSTILLATION THERAPY - Systems, methods, and apparatuses for providing installation therapy and negative-pressure therapy are described. The apparatus includes a housing and a moveable barrier disposed in the housing to form a dosing chamber and a pressure chamber. The apparatus also includes a therapy conduit configured to be fluidly coupled to a pressure source and to a canister. The apparatus further includes a fluid inlet fluidly coupled to the dosing chamber and configured to be fluidly coupled to a fluid source and a fluid outlet fluidly coupled to the dosing chamber and configured to be fluidly coupled to a dressing. A pressure inlet is fluidly coupled to the therapy conduit and the pressure chamber; and a check valve is disposed in the therapy conduit. | 2016-01-21 |
20160015874 | TUBE ATTACHMENT DEVICE FOR WOUND TREATMENT - The invention provides a vacuum tube attachment device for vacuum assisted wound dressings. The device is in the form of a patch that can be attached to the primary wound cover. The patch forms a substantially air-tight seal to the primary wound cover, and a vacuum tube is fixed to the patch such that the patch can be oriented on the wound cover to locate the tube near an opening in the cover to allow vacuum pressure to be communicated to the wound. The patch has an adhesive area around its perimeter for attaching the patch in a substantially air-tight seal to the wound cover at any convenient location on the cover. Several embodiments of the patch are described. | 2016-01-21 |
20160015875 | Foam Structure Wound Inserts For Directional Granulation - A wound treatment system comprises a wound-treatment apparatus and a wound dressing coupled to the apparatus. The wound dressing includes a foam structure wound insert having pores with a greater cross-sectional area when viewed from a first direction and a smaller cross-sectional area when viewed from an orthogonal direction. Methods for making such wound inserts may include compressing foam structure material having pores with a substantially uniform cross-sectional area. Methods for treating a wound using a wound insert. | 2016-01-21 |
20160015876 | EASILY ASSEMBLABLE BREAST INTERFACE FOR A BREAST PUMP - Breast interface ( | 2016-01-21 |
20160015877 | SYNCHRONIZED INTRAVENTRICULAR BALLOON ASSISTANCE DEVICE - System structured to facilitate a movement of a myocardial wall by pushing such wall with a force originated due to energy harvested by the system from a motion of a ventricular chamber without the use of any external energy. The system includes two pliable storage volumes fluidly interconnected by a passage to form a closed circuit that enables a movement of the fluid from one storage volume to another in response to a user input. Optionally, one of the storage volumes is encased in a cover characterized by a spatially-non-uniform distribution of elastic properties. The method of using the system includes juxtaposition of one of the storage volumes with a ventricular chamber and another of the storage volumes with a targeted myocardial wall to enable reversible flow of fluid within the system during a cardiac cycle. | 2016-01-21 |
20160015878 | Implantation Of A Transapical Ventricular Assist Device And Kit For Same - A method of implanting a blood pump in a heart of a mammalian subject includes maintaining a temporary plug in an inlet opening of a pump having a pump body and an outlet cannula projecting from the pump body, advancing the pump into a ventricle of the heart through a hole in a wall of the heart so that the inlet of the pump is disposed within the ventricle and the outlet cannula extends through a valve of the heart into an artery, and then withdrawing the temporary plug from the inlet of the pump. | 2016-01-21 |
20160015879 | CORRECTION AND OPTIMIZATION OF WAVE REFLECTION IN BLOOD VESSELS - The present invention provides methods and modalities that can modify wave reflection in the vascular system in order to create constructive interactions between existing wave dynamics and new reflective waves for the purpose of lowering the workload on the heart and increasing cardiac output, providing a viable option for the prevention and treatment of many heart conditions and diseases. | 2016-01-21 |
20160015880 | VENTRICULAR ASSIST DEVICE FOR INTRAVENTRICULAR PLACEMENT - The present invention, in one embodiment, is a blood pump for intraventricular placement inside a heart of a mammalian subject including a rigid elongate member having a length between proximal and distal ends and a bore extending along the length, an anchor element connected towards the proximal end of the rigid elongate member and mounted to the subject's heart, a pump having an inlet and an outlet, a rotor and at least one electric drive coil for magnetically driving the rotor, the pump connected at or adjacent to the distal end of the rigid elongate member remote from the anchor element and wiring extending through the bore to the pump, wherein the proximal end of the rigid elongate member extends past the anchor element to a position outside of the subject's heart. Additional embodiments of a blood pump, and various methods of intraventricular placement inside a heart of a mammalian subject are also considered. | 2016-01-21 |
20160015881 | CIRCULATION APPARATUS AND METHOD FOR CONTROLLING SAME - An artificial lung in a circulation apparatus can be monitored and be maintained in a safe condition without manual assistance. As an extracorporeal circulation mode starts, it is determined first whether or not gas exchange of the artificial lung is carried out within a normal range, based on oxygen concentration which is detected by an oxygen sensor positioned at a downstream place in the artificial lung. If the gas exchange is carried out within the normal range, an estimated value for gas supply volume of a gas blender is maintained. When oxygen concentration exceeding the normal range is detected, the gas blender is controlled so as to revise the gas supply volume downward. In addition, when oxygen concentration falls below the normal range, the gas blender is controlled so as to revise the gas supply volume upward. | 2016-01-21 |
20160015882 | MEDICAL FLUID PUMPING SYSTEMS AND RELATED DEVICES AND METHODS - This disclosure relates to medical fluid pumping systems and related devices and methods. In some aspects, a medical fluid pumping system includes a medical fluid pumping machine including a piston head that can be linearly displaced and a medical fluid cassette that can be secured to the medical fluid pumping machine. The medical fluid cassette includes a fastening member attached to a region of a flexible membrane overlying a fluid pump chamber, and the piston head is configured to be mechanically connected to the fastening member of the cassette. | 2016-01-21 |
20160015883 | CIRCULATION APPARATUS AND METHOD FOR CONTROLLING SAME - A highly reliable circulation apparatus promptly detects an abnormal state of a status value related to blood flowing in a circulation circuit with no particular operation performed. As an extracorporeal circulation mode starts, a user operates a pump first and waits until a flow rate is stabilized. Then, when the flow rate is stabilized, a predetermined value is added to or subtracted from the stabilized flow rate so as to set two threshold values which regulate an upper end and a lower end of a permissible state range. Then, it is monitored whether or not the flow rate is within the permissible state range regulated by the threshold values, and when the flow rate deviates from the permissible state range, an alarm is issued for notification. | 2016-01-21 |
20160015884 | APPARATUS AND METHOD FOR SEPARATING AND CONCENTRATING A COMPONENT OF A FLUID - A system for separating and concentrating a component of a whole material is disclosed. The whole material can include a material that has more than one component, such as whole blood that can include at least red blood cells, monocytes, and plasma. The system can include a substantially single container including a separation section and a concentration section wherein a component can be moved from the separation section, after a separation, to the concentration section to be concentrated. The concentrated component can then be withdrawn from the separation and concentration container for a selected procedure. | 2016-01-21 |
20160015885 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015886 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015887 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015888 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015889 | MULTI-MIX INFUSION BAG - A multi-mix infusion bag is provided. The multi-mix infusion bag includes a lower portion and an upper portion. The lower portion has a lower chamber and the upper portion includes a plurality of chambers. Each chamber is separated and contains a fluid agent. The multi-mix infusion bag is configured to transfer each fluid agent within each chamber of the upper portion into the lower chamber for mixing. The multi-mix infusion bag may include dispensing devices associated with each chamber, wherein the dispensing devices operate to transfer the fluid agents into the lower chamber for mixing. | 2016-01-21 |
20160015890 | SYSTEM AND METHOD OF VARIABLE DOSE GLUCAGON DELIVERY - Disclosed are systems and methods for variable dose glucagon delivery without the need to manually reconstitute the glucagon. These systems and methods mat be utilized with or without a separate continuous glucose monitor. The variability of the dose may be determined manually by the user, caregiver or responder, or by preprogrammed algorithms utilizing the input from an external sensor such as a continuous glucose monitor. | 2016-01-21 |
20160015891 | PORT CANNULA SYSTEM FOR PUNCTURING PORT CATHETERS - A port cannula system for puncturing implantable and implanted port catheters comprises a cannula holder, a cannula secured on the cannula holder and having a cannula tip. The cannula tip can be moved to at least one of a puncture position and a safety position. The port cannula system further includes a feeder connected to the cannula, and at least one support piece connected to the cannula holder for supporting the port cannula system on a patient's skin. The support piece is connected to the cannula holder by a hinge. The hinge permits height compensation, for example, if the patient's skin is not flat in the area of application or if the patient moves. The support piece, in conjunction with the hinge, thus represents a kind of leveling element. | 2016-01-21 |
20160015892 | Fluid Delivery Devices, Systems and Methods - Fluid delivery devices, systems and methods. The fluid delivery devices may be used to delivery fluid (e.g., insulin) to a user. The devices may have one or more inlets, and may be configured for use with an injection device, such as a syringe, and/or with a pump. | 2016-01-21 |
20160015893 | DIRECT PRESSURE-MEDIATED INTRA-BONE DELIVERY SYSTEM FOR CELLULAR THERAPEUTICS - Disclosed are devices, apparatus, and methods for directly infusing one or more materials into a bone of a patient. More particularly, devices, apparatus and methods are provided for direct intra-bone infusion, wherein intra-bone pressure is continuously monitored and adjusted during infusion such that intra-bone pressure does not exceed levels of systemic blood pressure. Such devices, apparatus and methods are particularly suitable for use in performing bone marrow transplants. | 2016-01-21 |
20160015894 | DISTRIBUTED MEDICATION DELIVERY METHOD HAVING AUTONOMOUS DELIVERY DEVICE - A method for delivering medication includes programming an operations processor of a medication delivery operations module to control the base function of medication delivery of a delivery device at a selectable rate and a selectable volume. An advanced medication delivery program is created by an advanced program processor that is part of an advanced interface module (“AIM”) located with the operations module in the same housing, although the processors are separate. When the advanced delivery program is complete and in a buffer, the operations processor executes the stored advanced delivery program under which the operations processor automatically varies at least one of the rate of delivery and volume of delivery values in accordance with the advanced delivery program autonomously without being under real time control of, or dependent on, any remote processor or data source, including the AIM. Support for PK applications is provided. | 2016-01-21 |
20160015896 | AUTOMATIC INJECTION DEVICE - An automatic injection device for delivering a dose from a medicine containing syringe includes a housing for containing the syringe, a force applicator for applying a force to eject medicine from the syringe, a trigger coupled to the force applicator for releasing the force applicator to cause an injection, a boot covering a needle attached to the syringe to protect and maintain sterility of the needle, and a mechanical interlock. The mechanical interlock prevents actuation of the trigger prior to removal of the boot. When the boot is removed, the mechanical interlock allows for actuation of the trigger. | 2016-01-21 |
20160015897 | Push Button Safety Injector - A push button safety injector includes a housing having a proximal end, a distal end spaced from the proximal end, and a longitudinal axis. An injection ram is positioned along the longitudinal axis and configured to actuate a fluid chamber. The injection ram is biased toward the distal end in an initial position. A sliding member is configured to retain the injection ram in the initial position. A safety member confines radial movement of the sliding member in the initial position and allows radial movement of the sliding member in an armed position. A button is moveable between an initial extended position and a depressed position. The button is engagable with the sliding member and configured to move the sliding member radially in the armed position. The sliding member releases the injection ram when the button is in the depressed position. | 2016-01-21 |
20160015898 | PLASMA OR CVD PRE-TREATMENT FOR LUBRICATED PHARMACEUTICAL PACKAGE, COATING PROCESS AND APPARATUS - A syringe comprising a wall having a generally cylindrical interior surface defining a lumen with a primer coating or layer between 1 and 1000 nm thick of SiOx Cy Hz, in which x is from about 0.5 to about 2.4, y is from about 0.6 to about 3, and z is from about 2 to about 9, on at least a portion of the interior surface, the primer coating or layer having an outside surface facing the interior surface of the barrel and an inside surface facing the lumen. A deposit of fluid lubricant on the inside surface of the primer coating or layer is further provided. | 2016-01-21 |
20160015899 | Assembly for a Drug Delivery Device Comprising a Feedback Feature - An assembly for a drug delivery device is provided, the assembly comprising a feedback feature. The feedback feature is configured to indicate an end of the dispense operation to a user by giving an audible and/or tactile feedback. | 2016-01-21 |
20160015900 | Drug Reconstitution System - A system including an adapter ( | 2016-01-21 |
20160015901 | Bearing Component for a Piston Rod of a Drug Delivery Device, Piston Rod Comprising the Bearing Component, and Drug Delivery Device - The bearing component comprises a contact surface inside a periphery, which surrounds a centre, and a coupling feature arranged inside the periphery for rotatably engaging a component of a piston rod perpendicular to the contact surface. The coupling feature includes at least one flexible feature extending from the periphery towards the centre, and the flexible feature is arranged to be deflected towards the periphery by a force exerted on the flexible feature in a direction towards the contact surface and deflected towards the centre by a force exerted on the flexible feature in the opposite direction. The flexible feature may have a sloping surface facilitating assembly and preventing disassembly in combination with a further component of the piston rod. The component of the piston rod may be a lead screw, and the piston rod may be used in a drug delivery device. | 2016-01-21 |
20160015902 | Pen-Type Drug Injection Device and Optical Dose Value Decoding Systme with Additional Sensor to Distinguish Between Dose Dialling and Dose Delivery Mode - An optical decoding system comprising: a first optical sensor configured to be directed at a first rotatable component of a drug delivery device; a second optical sensor configured to be directed at a second rotatable component of a drug delivery device; and a processor configured to: receive signals from the first optical sensor, wherein the signals from the first optical sensor represent encoded dosage values present on the first rotatable component; receive signals from the second optical sensor, wherein the signals from the second optical sensor represent whether the second rotatable component is rotating or not; and to determine from the received signals whether the drug delivery device is in a drug dose dialling mode or a drug dose delivery mode. | 2016-01-21 |
20160015903 | Rotary Sensor Module with Axial Switch - Sensor assembly comprising a first rotary sensor part with a plurality of individual electrically conducting sensor areas arranged in a pattern, a second rotary sensor part arranged rotationally relative to the first portion, the second part comprising a plurality of contact structures adapted to be in contact with conducting sensor areas on the first sensor rotary part. The contact structures are configured to engage and connect different sensor areas as the first and second part of the rotary sensor rotate relative to each, the created connections being indicative of a rotational position between the first and second portions. One of the contact structures is an actuatable contact structure being axially moveable relative to the first portion and having a connected position in which the actuatable contact structure is in contact with a sensor area and a disconnected position in which the actuatable contact structure is not in contact with a sensor area. | 2016-01-21 |
20160015904 | Drug Delivery Device and Method for Eliminating a Clearance of the Piston Rod for Drug Delivery Devices - The piston rod arrangement is in an assembled state before use and comprises a piston rod, a bung, which is intended to be driven by the piston rod, a body member, and a drive member. The piston rod is threadedly engaged with the body member, and the drive member is threadedly engaged with the piston rod and movable relative to the body member. A mechanism is provided defining unit steps of movement of the drive member and corresponding unit steps of movement of the piston rod. The piston rod is arranged in contact with the bung or at a distance from the bung that is less than a distance of one corresponding unit step of movement. When the piston rod, the bung and the drive member are assembled in the body member, the piston rod is advanced with respect to the body member towards the bung, until the piston rod is stopped by the bung. The drive member is rotated until the piston rod begins to advance again and the drive member is then stopped, and the piston rod is fixed at or near the position obtained. | 2016-01-21 |
20160015905 | INJECTION DEVICE HAVING A NEEDLE PROTECTION DEVICE - Injection device of fluid product ( | 2016-01-21 |
20160015906 | Method and Apparatus for Delivering a Therapeutic Substance Through an Injection Port - Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed. | 2016-01-21 |
20160015907 | DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY - Apparatuses for automatic medicament injection and methods for manufacturing automatic medicament injectors are described herein. In some embodiments, an apparatus includes a housing, a needle, an energy storage member, an actuator, a locking member, and a needle guard. The needle is configured to move between a first position and a second position. In its first position, the needle is contained within the housing. In its second position, at least a portion of the needle extends from the housing. The energy storage member has a first configuration and a second configuration and is configured to produce a force when moving between its first configuration and its second configuration to move the needle from its first position to its second position. The actuator is configured to move the energy storage member from its first configuration to its second configuration. The locking member is movably coupled to the distal end portion of the housing such that the locking member can be moved between a first position and a second position. In its first position, the locking member is configured to engage the actuator to prevent the actuator from moving the energy storage member to the second configuration. The needle guard is removably coupled to at least one of the distal end portion of the housing or a base movably coupled to the distal end portion of the housing. | 2016-01-21 |
20160015908 | PUNCTURE NEEDLE, AND METHOD AND APPARATUS FOR MANUFACTURING THE SAME - Provided is a method for producing a puncture needle, which causes no significant pain during use such as when pierced. The method for producing the puncture needle includes the step of processing a pipe-like metallic base material having at one end a grinding surface obtained by machine work with plasma generated in an atmosphere filled with a mixed gas mainly including a main gas and a reaction gas. | 2016-01-21 |
20160015909 | SYSTEM, RETAINER AND METHOD OF PROVIDING THERAPEUTIC TREATMENT FOR ACNE - According to an exemplary embodiment, a retainer for therapeutic treatment may be provided. The retainer for therapeutic treatment may include: a retainer that may retain a antimicrobial solution against tissue; a number of heating elements connected to the retainer for therapeutic treatment; a number of power supply cables connected to the number of heating elements; a number of antimicrobial solution delivery elements connected to the retainer for therapeutic treatment that may deliver an antimicrobial solution; a number of pieces of tubing having a first end connected to a antimicrobial solution reservoir and a second end connected to a number of antimicrobial solution delivery elements; a number of fiber optic cables having a first end connected to a light source; and a number of light terminations rigidly connected to the retainer for therapeutic treatment and connected to the second end of the fiber optic cable. | 2016-01-21 |
20160015910 | PHARMACEUTICAL INJECTION DEVICE AND STORAGE CASE THEREFOR - The present invention relates to a pharmaceutical injection device, and it is an object thereof to prompt the user to replace the injection needle as needed. To achieve this object, the present invention is configured such that a needle detector switch | 2016-01-21 |
20160015911 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015912 | AEROSOL GENERATOR FOR GENERATING AN INHALATION AEROSOL - An aerosol generator for generating an inhalation aerosol from an inhalation liquid, includes an intake duct for guiding air to a mouth of a user, and a nozzle, arranged in the intake duct for injecting the inhalation liquid into the intake duct. The nozzle is arranged for generating a Rayleigh droplet train of the inhalation liquid propagating along a droplet train propagation path. The intake duct includes at least two first orifices having at least partly opposing discharging directions extending towards the droplet train propagation path. The at least two first orifices are configured for providing respective first air streams in at least partly opposing directions so as to interact in the droplet train propagation path. | 2016-01-21 |
20160015913 | CERVICAL INSPECTION DEVICE AND METHOD FOR CERVICAL INSPECTION - A cervical inspection device includes a sealing body defined by an outer perimeter and being constructed for sealing placement about the vaginal introitus of a patient, the sealing body having an opening for introducing gas under pressure into the vaginal vault of the patient; and an extendable member connected to the sealing body in a region radially inwardly relative to the outer perimeter of the sealing body and being extendable in a direction transverse to the perimeter of the sealing body to form a generally tubular sheath. | 2016-01-21 |
20160015914 | MEDICAMENT DELIVERY DEVICES - A medicament delivery device ( | 2016-01-21 |
20160015915 | Element for Inhaling Medicinal Substances - The invention relates to an inhaler element, to be inserted inside a nasal cavity for inhaling medicinal substances, characterized in that it comprises, inside, a dispensing device, said dispensing device providing a convergent conduct for inlet of respiration flow and a divergent conduct for exit of respiration flow, and storage means for the substance to be inhaled, said storage means being provided in flow communication substantially in correspondence of the transition zone between said convergent conduct and said divergent conduct of said dispensing device. | 2016-01-21 |
20160015916 | POSITIVE AIRWAY PRESSURE SYSTEMS - Described here are positive airway pressure (PAP) systems and methods of using the same. The systems may comprise an air delivery matrix configured to deliver air from a chassis or housing and a user interface such as a mask. The systems may be wearable on a head of a patient, and in some instances may include an air bladder positioned between the chassis or housing and the head of the patient. | 2016-01-21 |
20160015917 | Phenotyping Of Sleep Breathing Disorders Using A Breathing Therapy Machine - An improvement for existing breathing therapy machines which allows the machine to determine a patient's dominant respiratory phenotype using an auto-titration mode and flow sensor. | 2016-01-21 |
20160015918 | SYSTEM, APPARATUS AND METHODS FOR SUPPLYING GASES - A system, apparatus and methods are provided for supplying gases to a user. The supply includes a sub-therapeutic mode and a pressure support mode for delivering therapy to a user. A flow diversion device or valve switches from a first mode corresponding with the sub-therapeutic mode of the system to a second mode corresponding with the pressure support mode of the system. In the first mode, the valve opens a larger flow path between the interior of the user interface and ambient air than in the second mode. | 2016-01-21 |
20160015919 | SYSTEMS AND METHODS FOR PROVIDING LOW-NOISE POSITIVE AIRWAY PRESSURE - The application discloses a noise attenuating system ( | 2016-01-21 |
20160015920 | BIOMIMETIC ARTIFICIAL SECURED AIRWAY - Disclosed herein is a biomimetic artificial secured airway for use with a patient ventilating system that reduces the incidence of ventilator-associated patient infections when compared with the infection rate attributable to existing endotracheal and tracheostomy tubes. | 2016-01-21 |
20160015921 | ADJUSTABLE POSITIVE AIRWAY PRESSURE OR VENTILATION SYSTEM - The present disclosure relates to a comfortable and adjustable nasal pillow configured to be part of a nasal pillow system that is part of a mask system used with a ventilation or PAP device. The nasal pillows are configured to have multiple degrees of freedom of rotation. | 2016-01-21 |
20160015922 | LOWER MOUNT FLEXING ORAL-NASAL MASK - The present invention provides a respiratory interface device including a mask having an upper, mask upper portion, a lower, mask lower portion, a flexible connecting member, and a patient contacting cushion. The flexible connecting member extends between, and is coupled to both, the mask upper portion and the mask lower portion. The flexible connecting member permits the mask upper portion and the mask lower portion to flex relative to one another. The patient contacting cushion is coupled to, and extends about, the mask upper portion, the mask lower portion, and the flexible connecting member. A brace assembly having a body with at least one mask coupling is provided. The brace is coupled to the mask upper portion and to the mask lower portion. The brace limits the outward rotation of the mask upper portion relative to the mask lower portion. | 2016-01-21 |
20160015923 | UNDIRECTIONAL FLEXION CLIP - A flexion coupling ( | 2016-01-21 |
20160015924 | FACIAL INTERFACE AND HEADGEAR SYSTEM FOR USE WITH VENTILATION AND POSITIVE AIR PRESSURE SYSTEMS - The present disclosure relates to a mask assembly system that has an adjustable headgear system with an inflatable cushion connected to the positive air pressure supply for conforming to a user's face. | 2016-01-21 |
20160015925 | FACIAL INTERFACE AND HEADGEAR SYSTEM FOR USE WITH VENTILATION AND POSITIVE AIR PRESSURE SYSTEMS - The present disclosure relates to a mask assembly system that has an adjustable headgear system with adjustable sidepiece for conforming to a user's face. Additionally, the mask assembly allows for detachable nasal pillows to be rotated about multiple degrees of freedom. | 2016-01-21 |
20160015926 | MEDICAL COMPONENTS WITH MICROSTRUCTURES FOR HUMIDIFICATION AND CONDENSATE MANAGEMENT - New medical circuit components and methods for forming such components are disclosed. These components include microstructures for humidification and/or condensate management. The disclosed microstructures can be incorporated into a variety of components, including tubes (e.g., inspiratory breathing tubes and expiratory breathing tubes and other tubing between various elements of a breathing circuit, such as ventilators, humidifiers, filters, water traps, sample lines, connectors, gas analyzers, and the like), Y-connectors, catheter mounts, humidifiers, and patient interfaces (e.g., masks for covering the nose and face, nasal masks, cannulas, nasal pillows, etc.), floats, probes, and sensors in a variety of medical circuits. | 2016-01-21 |
20160015927 | RAINOUT PROTECTION FOR RESPIRATORY THERAPY INCLUDING HUMIDIFICATION - A system for providing respiratory therapy to a subject using a subject interface ( | 2016-01-21 |
20160015928 | COATED TUBULAR SUPPORT MEMBERS AND METHODS OF MANUFACTURING SAME - A tubular support member located in a distal portion of an elongate flexible medical device is provided with a plurality of wall openings, e.g., axially-spaced, substantially transverse slots, formed therein to thereby increase a flexibility of the support member. A layer of sealing material overlays an outer surface the support member so as to provide a sealed portion of the support member including the wall openings, the sealing material having respective flexible invaginations formed therein overlaying the wall openings in the support member so that the sealing material does not substantially impede flexibility of the support member. | 2016-01-21 |
20160015930 | CONVECTION ENHANCED DELIVERY DEVICE AND SYSTEM - A convection enhanced delivery device comprises a support member and an elongated microcatheter carried by the support member. The microcatheter projects lengthwise away from the support member. The microcatheter includes a catheter lumen extending in a first direction. A fluid conduit carried by the support member. The fluid conduit includes a conduit lumen that extends in a second direction different than the first direction. The conduit lumen is in fluid communication with the catheter lumen. An inlet port and a connecting port are also carried by the support member. The inlet port is in fluid communication with the fluid conduit. The connecting port is separate from the inlet port and is in fluid communication with the fluid conduit. The connecting port is configured to engage an end portion of an external fluid conduit such that the external fluid conduit projects away from the connecting port and from the support member. | 2016-01-21 |
20160015931 | INTEGRATED CLEANING AND DISINFECTION DEVICE, SYSTEM AND METHOD - A single piece device enables medical clinicians to clean and disinfect both an injection port (needleless I.V. connector) and a vascular access catheter hub. The device has a body with a first end having a blind hole with a wall adapted to be engageable with the threads on the housing of an IV connector and a bottom surface adapted to engage the top surface of the IV connector. The device body has a second end defining a male-luer slip extending out of a recess. The male-luer slip is adapted to extend into a standard vascular access catheter hub such that it engages the inner walls of the catheter hub, and the recess is adapted to receive and be engageable with the outside thread element of the catheter hub. | 2016-01-21 |
20160015932 | Peripheral Catheter - Catheter assemblies that can reduce the occurrence of kinking of a catheter when the catheter assembly is secured to a surface of the patient's skin are provided herein. In accordance with various aspects, the catheter hub is shaped such that a catheter extending therefrom lies substantially flat on the patient's skin and/or the distance between the orifice from which the catheter hub extends and the surface of the patient's skin when the catheter assembly is secured thereto is minimized, thereby reducing the stress experienced by the catheter when the catheter hub is secured to the skin. | 2016-01-21 |
20160015933 | Method and System of Utilizing ECG Signal for Central Venous Catheter Tip Positioning - Disclosed herein are a method and a medical system for utilizing of a intravascular ECG signal for central venous catheter placement. The medical system is capable of detecting the position of a catheter tip and assessing its location relative to the cavoatrial junction. The detection and assessment are performed by a multiscale analysis of the complexity of the intravascular signal data points. | 2016-01-21 |
20160015934 | SHEATH - At least one distal side slope path is formed by penetrating an outer peripheral wall in the vicinity of a distal portion of a sheath main body and at least one proximal side slope path is formed by penetrating an outer peripheral wall in the vicinity of a proximal portion of the sheath main body. The at least one distal side slope path is inclined onto a proximal side from the outer peripheral surface to the inner peripheral surface of the sheath main body and the at least one proximal side slope path is inclined onto a distal side from the outer peripheral surface to the inner peripheral surface of the sheath main body. Therefore, blood is made to flow into a lumen and is made to flow out from the lumen along the blood flow in a blood vessel. | 2016-01-21 |
20160015935 | VASCULAR ACCESS SYSTEM AND METHOD OF USE - A vascular access system includes a catheter having an inner lumen in communication with an open distal end; a guidewire at least partially positioned in the catheter lumen and extending out the open distal end thereof, respective proximal and distal stops secured to the guidewire; and a centering device slidably mounted on the guidewire such that the centering device may freely within the catheter lumen relative to the guidewire between the proximal and distal stops, wherein the centering device substantially aligns a longitudinal axis of the catheter with a longitudinal axis of the guidewire proximate the centering device. | 2016-01-21 |
20160015936 | SYSTEM AND METHOD FOR IMPLANTING A CATHETER - A system for implanting a catheter in a urethra. The system includes a catheter having a valve disposed at a distal portion of the catheter. The valve may be operable in response to an external magnetic field. The system also includes a tool having a tip member extending into an opening at the distal portion of the catheter to couple the tool to the catheter. the system also includes an element extending from the tool. The catheter has an internal path that provides a conduit for the element to be extended through the valve to engage a proximal portion of the catheter. The tool is adapted use the element to stress the catheter and stiffen the catheter along the length of the catheter. Stiffening the catheter facilitates implantation of the catheter in the urethra by enabling pull forces, push forces, and torque forces to be transmitted from the tool through the catheter to the proximal portion of the catheter without undue stress on the urethra. The element is extendible and retractable to position the catheter between stressed and relaxed states while maintaining engagement to the catheter proximal portion. The tool, element and tip member are removable from the catheter after implantation of the catheter in the urethra. | 2016-01-21 |
20160015937 | TORQUE-BASED CATHETER ARTICULATION - A robotic surgical system configured for the articulation of a catheter comprises an input device, a control computer, and an instrument driver having at least one motor for displacing the pull-wire of a steerable catheter wherein the control computer is configured to determine the desired motor torque or tension of the pull-wire of a catheter based on user manipulation of the input device. The control computer is configured to output the desired motor torque or tension of the pull-wire to the instrument driver, whereby at least one motor of the instrument driver implements the desired motor torque to cause the desired pull-wire tension to articulate the distal tip of the catheter. The present embodiment further contemplates a robotic surgical method for the articulation of a steerable catheter wherein an input device is manipulated to communicate a desired catheter position to a control computer and motor torque commands are outputted to an instrument driver. The robotic system may further comprise a torque sensor. The robotic system may also incorporate closed loop feedback in which data from the torque measuring device is used to ensure that the torque in the motor or tension in the pull-wire closely matches the motor torque command from the control computer. | 2016-01-21 |
20160015938 | Head Mounted IV Holder Assembly and Method of Use - A head mounted catheter holder assembly is disclosed comprising a head mount assembly and an one or more catheter holders. Said one or more catheter holders comprises a first catheter holder. Said one or more catheter holders attach to said head mount assembly. Said head mount assembly releasably attaches to a head of a user. Said one or more catheter holders releasably hold a one or more catheter tubes. | 2016-01-21 |
20160015939 | ABSORBENT AND ANTIMICROBIAL CUFF FOR CATHETER PLACEMENT - An cuff is described that facilitates the attachment of the catheter to a patient's skin for creating a secure attachment between the catheter and the patient's skin. The cuff that facilitates the attachment of the catheter to the patient's skin can be an absorbent and antimicrobial cuff. In some embodiments, the cuff can be utilized with a skin strip and/or a cover strip. | 2016-01-21 |
20160015940 | GUIDING CATHETER ASSEMBLY AND METHOD OF USING THE SAME - A guiding catheter assembly includes a guiding catheter which has a catheter main body and a protective sheath in covering relation to the outer peripheral portion of the catheter main body, and a dilator insertable into the guiding catheter. The protective sleeve can be moved in an axial direction with respect to the catheter main body. The protective sheath has a thin film portion which is formed of a tube-like thin film and through which the catheter main body can be inserted, and a housing portion which includes a lumen through which the catheter main body can be inserted. | 2016-01-21 |
20160015941 | CATHETER ASSEMBLY - A catheter assembly includes an inner needle having a sharp tip at a distal end thereof; a catheter in which the inner needle is disposed; a tip protective member having an insertion hole through which the inner needle is insertable, the tip protective member being configured to cover at least a tip of the inner needle when the inner needle is withdrawn; and a shutter member which is arranged in an interior of a shutter accommodating section provided in the tip protective member, the shutter member being configured to be deformed and thereby block a movement path of the inner needle in the shutter accommodating section when the inner needle is retracted to a predetermined position relative to the tip protective member. The shutter accommodating section includes a needle guide configured to guide movement of the inner needle. | 2016-01-21 |
20160015942 | CATHETER ASSEMBLY - A catheter assembly includes an inner needle having a sharp tip at a distal end thereof; a catheter in which the inner needle is disposed; a catheter hub disposed on a proximal end side of the catheter and through which the inner needle is insertable; an inner needle hub disposed on a proximal end side of the inner needle; and a protector mounted detachably on the inner needle hub, the protector being configured to cover at least the tip of the inner needle. The protector includes a movement prevention unit, the movement prevention unit being configured to prevent movement of the catheter toward the tip with respect to the inner needle in a state in which a distal end side of the inner needle protrudes a predetermined length from the catheter. | 2016-01-21 |
20160015943 | Intravenous Catheter Insertion Device and Method of Use - A catheter insertion device includes a housing, a needle, a catheter, a guidewire, and an actuator mechanism including a biasing member. The needle is attached to a needle carrier having a proximal end disposed in the housing, the needle having an insertion position and a retraction position with respect to the housing. The catheter is positioned coaxially around the needle. The guidewire has a distal end positioned in a lumen of the needle in a withdrawn position, the guidewire being translatable to an advanced position in which the distal end extends distally from a tip of the needle. The guidewire may include a distal end with a coiled configuration. Actuating the actuator mechanism releases the biasing member to simultaneously translate the needle and the guidewire, the needle from the insertion position to the retraction position, and the guidewire from the advanced position to the withdrawn position. | 2016-01-21 |
20160015944 | Guide Catheters with Guidewire Deflection Features - A guide catheter system for use in treating the sinus cavity or Eustachian tube is described. The system includes a guide catheter that has a proximal end and a distal end and an elongate shaft between the proximal end and the distal end and a guidewire. The guide catheter includes a deflection feature on a distal tip of the distal end for deflecting the guidewire at a predetermined angle. | 2016-01-21 |
20160015945 | Intravenous Catheter Insertion Device and Method of Use - A catheter insertion device includes a housing, a needle, a guide wire, and a catheter disposed coaxially over the needle. The needle has a proximal end in the housing and a distal end extending from a distal end of the housing in an insertion position. The guide wire has a distal portion disposed in a lumen of the needle in a withdrawn position. The guide wire may include a safety tip having a non-coiled configuration in the withdrawn position and a coiled configuration in an advanced position. The catheter insertion device may include a sliding member attached to the guide wire, wherein movement of the sliding member translates the guide wire from the withdrawn position to the advanced position. | 2016-01-21 |
20160015946 | BALLOON CATHETER - Provided is a balloon catheter in which a balloon can smoothly deflate even when being pulled. A balloon catheter includes a balloon that can inflate and deflate, a hollow distal shaft that communicates with the balloon and in which an inner shaft is inwardly provided, a hollow intermediate shaft that is connected to a proximal end side of the distal shaft so as to communicate therewith, a hollow proximal shaft that overlaps a proximal end side of the intermediate shaft so as to be connected thereto and that communicates with the intermediate shaft, and a reinforcement body that extends from the proximal shaft to the distal shaft and is fixed to the proximal shaft, in which the intermediate shaft is more flexible than the distal shaft, and in an overlapped portion in which the intermediate shaft and the proximal shaft overlap each other, a non-fixing portion in which the intermediate shaft and the proximal shaft overlap each other without being fixed extends to a distal end side relative to a fixing portion in which the intermediate shaft is fixed to the proximal shaft. | 2016-01-21 |
20160015947 | DEVICE FOR INDEPENDENTLY INFLATING, DEFLATING, SUPPLYING CONTRAST MEDIA TO AND MONITORING UP TO TWO BALLOON CATHETERS FOR ANGIOPLASTY - An adaptable inflation device for up to two balloon catheters for angioplasty includes a plurality of three port valves controlling flow to two fluid channels each coupled at an outlet to a balloon catheter for angioplasty. A single in line pressure gauge, which may be removable, monitors pressure of each channel. Each balloon catheter may be inflated and deflated, sequentially inflated, simultaneously inflated, sequentially deflated, simultaneously deflated, inflated to the same pressures, inflated to different pressures, partially deflated, and fully deflated. | 2016-01-21 |
20160015948 | DEVICES, METHODS AND KITS FOR DELIVERY OF THERAPEUTIC MATERIALS TO A PANCREAS - An apparatus includes an inner catheter that is coupled to a handle and defines a lumen configured to receive a guidewire. An outer catheter is movably coupled to the handle and defines a first lumen in fluid communication with a distal opening and that is configured to introduce a therapeutic agent through the distal opening and into a target pancreatic artery(ies). The outer catheter defines a second lumen configured to receive at least a portion of the inner catheter. An actuator is coupled to the handle and configured to move the outer catheter relative to the handle. A first occlusion element is coupled to the inner catheter and a second occlusion element is coupled to the outer catheter and disposed proximal to the first occlusion element. A distance between the first occlusion element and the second occlusion element is adjustable when the outer catheter is moved relative to the handle. | 2016-01-21 |
20160015949 | APPARATUS AND METHOD FOR DEPLOYMENT OF A BRONCHIAL OBSTRUCTION DEVICE - An apparatus and method deploy a self-expandable bronchial obstruction device in an air passageway. The apparatus includes a catheter configured to be passed down the trachea. The apparatus further includes a capsule for housing the self-expandable bronchial obstruction device in a sterile environment. The capsule is configured to be advanced down the catheter. The capsule further includes a tubular extension. The capsule has a breakable seam so as to release the bronchial obstruction device in the air passageway upon a proximal force being exerted upon the bronchial obstruction device. The method includes guiding a conduit down a trachea into the air passageway. The method further includes advancing a capsule having a bronchial device therein down an internal lumen of the conduit into the air passageway. The method further includes releasing the bronchial device from the capsule. The method further includes deploying the bronchial device into the air passageway. | 2016-01-21 |
20160015950 | BALLOON CATHETER WITH IMPROVED COLUMN STRENGTH AND TORQUE TRANSMISSION - A balloon catheter capable of delivering torque and pushing through obstructions includes a relatively weak balloon segment of a catheter and rotatable asymmetric tip. A reinforcement sleeve increases column strength and torque transmission to push the balloon and rotate the tip to facilitate passage through said obstructions. The tip is preferably asymmetric around its axis, usually being beveled, and the reinforcement slide includes a slide lock mechanism which increases shaft flexibility after balloon deployment. | 2016-01-21 |
20160015951 | METHOD AND DEVICE FOR PLANNING A DIRECT INFUSION INTO HEPATIC TISSUE - A method for planning an infusion into hepatic tissue into a patient includes: obtaining anatomical and/or physiological patient data of the patient's liver or a region of the liver; determining at least one patient parameter from the patient data; planning the infusion using the anatomical patient data, physiological patient data, and/or at least one patient parameter, wherein planning includes determining how an administered substance is distributed in the tissue and/or how the administered substance influences physiological properties of the tissue; and determining a distribution and/or effectiveness of a therapeutic agent administered with the substance or after the substance. | 2016-01-21 |
20160015952 | A MICRONEEDLE PATCH - The present invention provides a microneedle patch which can solve the problem that microneedle production is difficult and requires high accuracy, the problem that time and mental burdens on a health professional and a patient are large, and the problem caused by compounding a plurality of drugs. The microneedle patch comprises a large number of drug-carrying microprojections | 2016-01-21 |
20160015953 | Systems and Methods for Therapeutic Agent Delivery - According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject. | 2016-01-21 |
20160015954 | Methods and Systems for Modulating Medicants Using Acoustic Energy - This invention provides methods and systems uniquely capable of enhancing medicant delivery and/or effectiveness through the use of energy to predictably disrupt membranes and mechanically and thermally modulate cells and tissues. In exemplary embodiments, the methods and systems disclosed herein are capable of modulating multiple layers of tissue. In an exemplary embodiment, the energy is acoustic energy (e.g., ultrasound). In other exemplary embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents, or various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling. Medicants can be first introduced to the region of interest by diffusion, circulation, and/or injection. An exemplary system for enhancing medicant delivery and/or effectiveness comprises a control system, a probe, and a display or indicator system. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention. | 2016-01-21 |
20160015955 | EXTRACORPOREAL MEMBRANE OXYGENATION CANNULA HEMOSTATIC PLUG - The present invention is a hemostatic plug for use with Extracorporeal Membrane Oxygenation (ECMO) cannulas that allow quick access to the blood vessel as well as maintaining a sterile environment to resume ECMO, if needed. It is designed to be a universal fit for use with adult ECMO circuits. The plug consists of a hemostatic membrane, a collection chamber and a cap. The membrane is designed to allow catheter delivery of up to a 19 French diameter through the ECMO cannula. The collection chamber allows the distribution of blood pressure over a broader surface, which allows additional hemostasis in addition to the membranes. The plug is then further reinforced with a cap that provides additional hemostasis, but when removed, allows hemostatic access into the blood vessel via the ECMO cannula. | 2016-01-21 |
20160015956 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015957 | SMART CONNECTION INTERFACE - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination. | 2016-01-21 |
20160015958 | CONNECTOR AND INFUSHION SET - A connector includes a housing defining a male connector insertion section into which a male connector is inserted from the outside and an elastic valve body having a slit and blocking the male connector insertion section. The elastic valve body includes a top face having the slit and a bottom face located opposite to the top face. The housing includes a holding section having contact with the top face and the bottom face of the elastic valve body to hold the elastic valve body. The holding section surrounds the slit when the valve body is viewed from the top face. The diameter of a bottom face side holding section having contact with the bottom face is smaller than the diameter of a top face side holding section having contact with the top face. | 2016-01-21 |
20160015959 | Carrier Assembly with Caps for Medical Connectors - An assembly for mounting medical connector caps includes a carrier formed from a sheet of material and having an array of holes. The assembly also includes a plurality of medical connector caps. Each cap is inserted into one of the holes of the array. The assembly also includes a plurality of sealing tabs. The tabs may be retained on the carrier by friction fit into the holes of the carrier. The carrier may also include a mounting hole to hang on a pole of an IV line. | 2016-01-21 |
20160015960 | Closure Device For a Fluid System For Medical Purposes - A closure device for a fluid system for medical purposes is disclosed. The closure device includes a support housing, which has at least one opening to a fluid reservoir or a fluid line, and also with a connection piece, which includes a Luer connecting portion for connecting to a syringe or some other Luer connection part, and with an elastically deformable closure membrane, which closes a fluid passage of the connection piece and opens it when the syringe or other Luer connection part is connected. A nonreturn valve is configured for opening both in the direction of the connection piece and in the direction of the opening to the fluid reservoir or to the fluid line is arranged in the support housing at a distance from the closure membrane in the direction of the fluid. The closure device has applications in several areas, including in infusion systems for medical purposes. | 2016-01-21 |
20160015961 | NEEDLELESS CONNECTOR WITH COMPRESSIBLE VALVE - Needleless connectors are described. An example needleless connector includes a housing and a compressible valve. The housing may define an internal cavity and may include a body section having a first port and one or more internal contact tabs and a base section having a valve mount and a second port. The compressible valve may be disposed within at least a portion of the internal cavity and be movably retained within the housing. The compressible valve may include a flange portion for securing the compressible valve within the housing. A central longitudinal axis of the housing may be defined by a coaxial arrangement of the first and second port. The one or more internal contact tabs may be arranged to contact an outer side surface of the flange portion such that a radial force substantially orthogonal to the central longitudinal axis is provided for securement. | 2016-01-21 |
20160015962 | Smart Patch For Wound Management - A flexible patch is provided that is capable of emitting light in the UV, visible, and/or infrared electromagnetic spectrums. The patch contains a feedback process and system using one or more sensors and a controller on the patch to ( | 2016-01-21 |
20160015963 | SURGICAL INSTRUMENT FOR REMOVING AN IMPLANTED OBJECT - Methods and devices for separating an implanted object, such as a pacemaker lead, from tissue surrounding such object in a patient's vasculature system. Specifically, the tissue separating device includes a handle, an elongate sheath and a circular cutting blade that may extend from the distal end of the sheath upon actuating the handle. The elongate sheath, particularly its distal end, includes a non-uniform wall thickness having one or more thicker portions in the outer sheath, particularly the outer cam member, and/or one or more thicker portions in an inner member disposed radially inward of the blade. | 2016-01-21 |