05th week of 2015 patent applcation highlights part 50 |
Patent application number | Title | Published |
20150031774 | RASAGILINE ORALLY DISINTEGRATING COMPOSITIONS - This invention provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, and particles having a non-filamentous microstructure of at least two sugar alcohols. This invention also provides a solid pharmaceutical composition comprising rasagiline or a pharmaceutically acceptable salt of rasagiline, a mixture of a disintegrant, a flow agent and particles having a non-filamentous microstructure of at least two sugar alcohols, a supplemental sugar alcohol, a supplemental flow agent, and a supplemental disintegrant. This invention further provides a method of treating a subject afflicted with Parkinson's disease comprising administering to the subject a therapeutically effective amount of the solid pharmaceutical composition, thereby treating the subject. Finally, this invention provides a process of making such solid pharmaceutical compositions. | 2015-01-29 |
20150031775 | COMPOSITION AND METHOD FOR AFFECTING MALE AND FEMALE HORMONE LEVELS - A composition and method for treating infertility and sexual dysfunction of a male or female human by balancing hormone levels of cortisol, dehydroepiandrosterone sulfate, testosterone, progesterone, and estradiol in the human. The composition comprises effective amounts of spermine and spermidine, administered at least once daily for a period of at least thirty days. | 2015-01-29 |
20150031776 | METHOD OF PREVENTING, TREATING AND DIAGNOSING DISORDERS OF PROTEIN AGGREGATION - Disclosed are methods of preventing, treating, or diagnosing in a subject a disorder in protein folding or aggregation, or amyloid formation, deposition, accumulation, or persistence consisting of administering to said subject a pharmaceutically effective amount of inositol stereoisomers, enantiomers or derivatives thereof. | 2015-01-29 |
20150031777 | miRNA FINGERPRINT IN THE DIAGNOSIS OF WILMS' TUMOUR - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 2015-01-29 |
20150031778 | PROCESS AND SYSTEM FOR RECOVERING POLYAMIDES AND POLYMERS FROM COMPOSITE ARTICLES - A process and system for recovering at least one polyamide from one or more composite materials is provided. The process comprises dissolving the at least one polyamide present in the one or more composite materials in a solvent. The process further comprises separating at least one undissolved polymer from the solution by filtration. Furthermore, the process comprises evaporating part of the solvent from the solution containing the at least one polyamide. Also, the process comprises neutralizing, using an alkali, the solvent remaining with the at least one polyamide. In addition, the process comprises washing, filtering and drying the mixture comprising the at least one polyamide to obtain polyamide. | 2015-01-29 |
20150031779 | PREPARATION OF MOLECULAR IMPRINTED POLYMERS BY CROSS-LINKING - Provided is an improved method for preparation of insoluble molecular imprinted polymers (MIPs), the method comprising: a) providing soluble or semi-soluble MIPs that 1) substantially all bind template agents and 2) have sizes which enable their separation in a chromatographic step utilizing packed bed chromatography, b) cross-linking the template agent binding soluble MIPs provided in step a so as to obtain insoluble template agent binding MIPs, and c) optionally isolating, concentrating or purifying the MIPs obtained by the cross-linking in step b. In an interesting embodiment, step a includes an affinity purification procedure, which ensures that the MIPs provided in step a are indeed all binders of the template. | 2015-01-29 |
20150031780 | METHOD FOR PREPARING MICROPOROUS POLYOLEFIN FILM BY THERMALLY-INDUCED PHASE SEPARATION METHOD - The present invention discloses a method for preparing a microporous polyolefin film comprising: a step of injecting a composition comprising polyolefin 30 to 60 wt % and a diluent, which can make liquid-liquid phase separation with the polyolefin thermodynamically 40 to 70 wt %, into an extruding machine, and melting and kneading thereof to prepare a single phase melt; and a step of extruding the melt while conducting liquid-liquid phase separation by passing through a section having the temperature below the liquid-liquid phase separation temperature and forming thereof in the form of a sheet, and a microporous polyolefin film prepared according to the method. | 2015-01-29 |
20150031781 | ADDITIVE FOR ADJUSTING THE GLASS TRANSITION TEMPERATURE OF VISCO-ELASTIC POLYURETHANE SOFT FOAMS - The present invention is directed to the use of a disalt of malic acid in the production of a polyurethane foam to lower the glass transition temperature of the polyurethane foam obtained, wherein the disalt of malic acid is added to the reaction mixture comprising at least a polyol component, an isocyanate component, a catalyst to catalyse urethane or isocyanurate bond formation, an optional blowing agent and optionally further additives, and also to a polyurethane foam having a glass transition temperature of −20° C. to 15° C., which polyurethane foam is characterized in that it comprises disalts of malic acid or reaction products thereof with an isocyanate component, wherein the fraction accounted for by the disalts and the reaction products thereof with an isocyanate component is below 0.08 wt % based on the polyurethane foam. | 2015-01-29 |
20150031782 | NOVEL THIOL-CONTAINING DUAL CURE POLYMERS AND METHODS USING SAME - The invention includes a composition comprising a vinyl sulfone monomer, a thiol monomer and an acrylate monomer. In one embodiment, the thiol monomer reacts with the vinyl sulfone monomer preferentially over the acrylate monomer, and this differential selectivity allows for the control of the architecture of crosslinking polymer network. The invention further includes a composition comprising an electrophilic monomer, a nucleophilic monomer, a nucleophilic catalyst and an acid, wherein the concentrations of the nucleophilic catalyst and acid are selected as to provide a specific induction time for the polymerization reaction of the composition. | 2015-01-29 |
20150031783 | LIQUID MINERAL COATING - A liquid mineral coating is disclosed which formulation includes calcium hydroxide (Ca(HO)2) and magnesium hydroxide Mg(OH2) associated with an organic polymer, allowing control of fungal growth and coating blistering or peeling due to rising moisture in the substrate, keeping the environment stable, without the need of adding stabilizers, such as D-Sorbitol, commonly used in conventional mineral coatings. | 2015-01-29 |
20150031784 | METHOD TO PREVENT DEACTIVATION OF METAL CATALYSTS IN CATALYTIC POLYMERISATION PROCESSES - The present invention relates to a method to prevent deactivation of the metal catalyst in a catalytic polymerisation process of polymeric binders whereby pyrithione biocides are present which method comprises the addition of a Zn, Cu or Na salt selected from Zn, Cu or Na salts of fatty acids such as e.g. Zn, Cu or Na octoate, Zn, Cu or Na acrylate, Zn, Cu or Na neodecanoate, or Zn, Cu or Na salts of beta diketones such as e.g. Zn, Cu or Na acetylacetonate. | 2015-01-29 |
20150031785 | ADHESIVE COMPOSITION AND ADHESIVE SHEET - A pressure-sensitive adhesive composition containing an acrylic copolymer (A) having a structural unit (a1) derived from an alkyl (meth)acrylate (a1)′ and a structural unit (a2) derived from a functional group-containing monomer (a2)′, a crosslinking agent (B), and a photochromic dye (C) selected from a group consisting of dithienylethene-based compounds, oxazine-based compounds and naphthopyran-based compounds has a relatively rapid rate of color change from colored to colorless after termination of irradiation with UV rays, has excellent photochromic performance and can be a pressure-sensitive adhesive layer of a colorless pressure-sensitive adhesive sheet. | 2015-01-29 |
20150031786 | Process for Producing a Powder Comprising an Extruded Carrier With an Active Compound - This invention provides processes for forming powders comprising at least one active compound and at least one carrier. The processes comprise (i) heating at least one active compound to at least its melting point or softening point; and (ii) in an extruder, combining at least the at least one active compound with at least one carrier, to form combined ingredients, and cooling the combined ingredients as they pass through the extruder, such that the combined ingredients exit the extruder at about ambient temperature in the form of a powder having particles sized so that about 95 wt % or more of the powder passes through a screen of about 8 standard U.S. mesh. | 2015-01-29 |
20150031787 | FRICTION MATERIAL - One variation includes a friction material wherein the friction material may be fabricated from fibers, particles, a chemical binder, and a resin bonding agent wherein the particles are aggregated. | 2015-01-29 |
20150031788 | LOW COPPER-CONTAINING FRICTION MATERIAL COMPOSITION USED AS BRAKE PAD - A low copper-containing friction material composition used for brake pad is provided, which consists of the following components by weight parts: 4˜6 parts of aramid fiber, 2˜2.5 parts of tyre powder, 5˜6 parts of heavy magnesia, 5˜6 parts of red vermiculite, 8˜10 parts of ceramic fiber, 3.5˜5 parts of magnetite, 7˜8 parts of boron-containing phenolic resin, 15˜17 parts of calcium sulfate crystal whisker, 16-18 parts of potassium titanate, 15˜17 parts of barite, 5.5˜7 parts of flake graphite, 6˜8 parts of friction powder of cashew nut oil, 6˜8 parts of calcined petroleum coke, 1.5˜2 parts of boron nitride, 5˜7 parts of flake aluminum powder, 0.4˜0.5 parts of pure copper fiber, 0.4˜0.6 parts of black silicon carbide. Said friction material composition is highly environmental friendly and has low content of heavy metal, wherein the content of copper is lower than 0.5%, and an excellent friction layer and transfer membrane can be formed when using said friction material composition. Said friction material composition has a satisfactory high temperature and thermal decay resistant performance, long service life, good abrasion resistance and stable friction coefficient. | 2015-01-29 |
20150031789 | RUBBER TYRE COMPOUND - A rubber tyre compound having a polymer base; a curing system, which cures the polymer base by means of heating; and basalt fibres with a length/diameter ratio ranging from 20 to 2000. | 2015-01-29 |
20150031790 | MICROGEL-CONTAINING TREAD MIXTURE FOR WINTER TYRES - The present invention relates to vulcanizable rubber mixtures comprising at least the following components:
| 2015-01-29 |
20150031791 | Rubber Composition for Tire Treads - The invention provides a rubber composition for use in tire treads that enhances low rolling resistance, wet performance and wear resistance to conventional levels or above. It comprises, per 100 parts by weight of a diene rubber containing from 35% to 89% by weight of a modified conjugated diene polymer rubber and from 11% to 40% by weight of a butadiene rubber, from 3 to 60 parts by weight of an aromatic modified terpene resin and from 100 to 150 parts by weight of a filler; the filler containing not less than 70% by weight of a silica; a ratio Wte/Wbr of the compounded amount of the aromatic modified terpene resin Wte to the compounded amount of the butadiene rubber Wbr being from 0.5 to 1.3; the modified conjugated diene polymer rubber having a terminal modified group including a functional group that interacts with the silica; an aromatic vinyl unit content being from 38% to 48% by weight of the modified conjugated diene polymer rubber, a vinyl unit content being from 20% to 35% by weight of the modified conjugated diene polymer rubber, and a weight-average molecular weight of the modified conjugated diene polymer rubber being from 600,000 to 1,000,000; and a softening point of the aromatic modified terpene resin being from 100° C. to 150° C. | 2015-01-29 |
20150031792 | Silica-Filled Rubber Composition And Method For Making The Same - Disclosed is a method of preparing a rubber composition comprising the steps of (a) blending in at least one preparatory mixing step at least one natural or synthetic rubbery polymer, a silica filler, a silica coupling agent, and at least one vulcanization accelerator; and (b) subsequently blending therewith in a final mixing step a sulfur curative, wherein the average glass transition temperature of the polymer(s) is −55° C. or less. | 2015-01-29 |
20150031793 | MULTIFUNCTIONAL SYNTACTIC FOAMS - A multifunctional syntactic foam including a matrix material and hollow particles, where a first and second material property of the syntactic foam are tailored on the basis of the wall thickness and volume fraction of the hollow particles. | 2015-01-29 |
20150031794 | Method For In-Situ Synthesis Of Silicon Nanoparticles - The invention relates to a method for in-situ synthesis of silicon nanoparticles in a thermosetting polymeric matrix, the thermosetting and thermoset matrices obtained in this way and a material including same. The method includes the following steps: a) forming an aqueous-phase/organic-phase inverse emulsion, wherein the aqueous phase includes at least a basic catalyst and the organic phase includes at least a non-cross-linked (co)polymer precursor chosen from an aliphatic, cycloaliphatic or aromatic epoxy resin precursor, a polyester-imide precursor, an unsaturated/epoxy polyester (co)polymer precursor, a polyether/epoxy (co)polymer precursor and a polyurethane precursor; b) introducing, into the inverse emulsion formed in step a), at least one silicon precursor forming a complete network whereof the rate of hydrolysis is greater than the cross-linking speed of the (co)polymer and c) stirring the mixture obtained in step b) and heating to a temperature between 20° C. and 70° C. | 2015-01-29 |
20150031795 | METHOD FOR PRODUCING RUBBER COMPOSITION - After step (I) of kneading a diene rubber and a carbon black to be mixed with each other, and then discharging the resultant mixture containing the diene rubber and the carbon black from an internal mixer, step (II) of kneading the mixture again in the internal mixer to crush a re-aggregate of the carbon black in the mixture, and step (III) of charging the dihydrazide compound into the internal mixer, and kneading the mixture and the dihydrazide compound to be mixed with each other are carried out. The period of step (II) for the kneading is 15 seconds or longer, and the rotating speed of the stirring rotor of the internal mixer is 35 rpm or more. The period of step (III) for the kneading is 40 seconds or longer, and the rotating speed of the stirring rotor of the internal mixer is from 15 to 25 rpm. | 2015-01-29 |
20150031796 | METHOD FOR MAKING FUNCTIONALIZED SILICA FOR RUBBER MASTERBATCH - A method for blending functionalized silica with styrene butadiene rubber or ethylene propylene diene monomer rubber can include silica and an organosilane chemically and covalently bound to a surface of the silica. The organosilane can be derived from an organic silane with a functional group. A silica rubber masterbatch for complexing with an emulsion styrene butadiene rubber latex, a synthetic polymer, a natural polymer, or combinations thereof can include the functionalized silica with the organosilane or a blend of organosilanes chemically and covalently bound to a surface of the silica. Each organosilane can have an average tetrameric structure having a T | 2015-01-29 |
20150031797 | Room Temperature-Curable Coating Composition - To provide a room temperature-curable coating composition that has superior weatherability, in which cracking over time is suppressed due to by-products not being produced when curing, and the environmental burden is low due to an organic solvent not being included. This invention relates to a room temperature-curable coating composition comprising (A) an epoxy-functional organopolysiloxane and (B) an amino-functional organopolysiloxane. | 2015-01-29 |
20150031798 | COMPOSITE MATERIALS FOR USE IN HIGH VOLTAGE DEVICES - A composite material is disclosed for use in a high-voltage device having a high-voltage electrical conductor, the material containing a polymeric matrix and at least one fiber embedded in the polymeric matrix, the fibers having an average diameter of less than about 500 nm. | 2015-01-29 |
20150031799 | CEMENT AND CONCRETE WITH REINFORCED MATERIAL - Provided are compositions, methods and systems including cementitious compositions and reinforcing materials wherein the cementitious composition comprises a metastable component. | 2015-01-29 |
20150031800 | POLYMERIC MATERIALS INCLUDING A GLYCOSAMINOGLYCAN NETWORKED WITH A POLYOLEFIN-CONTAINING POLYMER - The present invention relates to polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer. The present invention also relates to hydrogels containing the polymeric materials. The present invention further relates to methods of synthesizing the polymeric materials and hydrogels of the present invention. | 2015-01-29 |
20150031801 | Wear Polytetrafluoroethylene (PTFE) Fiber and Method of Making Same - A dispersion spun fluoropolymer fiber prepared from non-melt-processible polytetrafluoroethylene particles and aluminum oxide particles. The concentration of Al | 2015-01-29 |
20150031802 | BIODEGRADABLE POLYMER COMPOSITION FOR THE MANUFACTURE OF ARTICLES HAVING A HIGH HEAT DEFLECTION TEMPERATURE - This invention relates to a biodegradable polymer composition which is particularly suitable for use in the manufacture of articles having a high heat deflection temperature (HDT) by injection moulding and thermoforming. | 2015-01-29 |
20150031803 | PLASTIC STRAPPING BAND FOR WRAPPING AN OBJECT AND OF METHOD OF MAKING THE BAND - The present invention relates to a plastics-material strapping band ( | 2015-01-29 |
20150031804 | CELLULOSE NANOFIBERS AND METHOD FOR PRODUCING THE SAME, COMPOSITE RESIN COMPOSITION, AND MOLDED BODY - Cellulose nanofibers include: a linear portion; and a curved portion, in which an average of a length of the linear portion and an average of a maximum diameter of the linear portion have a relationship that satisfies the following Equation (a): | 2015-01-29 |
20150031805 | Phosphorus Containing Flame Retardants - Certain phosphonic acid salts heated at temperatures over 200° C. generate thermally stable, highly efficient flame retardant materials well suited for use as flame retardant additives in polymers. The flame retardants of the invention can be used as the sole flame retardant in a composition or in combination with other flame retardants, synergists or adjuvants. | 2015-01-29 |
20150031806 | MOISTURE CURABLE COMPOSITIONS WITH ENHANCED ELONGATION AND TEAR STRENTGH PROPERTIES - Moisture-curable compositions are provided which comprises a moisture-curable silylated resin, a flexibilizer and at least one curing catalyst. The cured compositions possess enhanced elongation and tear properties, and are highly suitable for applications such as adhesives, sealants, coatings, gaskets, industrial rubber goods, and the like. | 2015-01-29 |
20150031807 | CLEAR COAT COMPONENT - A curable clear coat component for use in a two-component clear coat coating composition system is provided. The curable clear coat component comprises A) a polyaspartic acid ester or a hydroxyl functional binder or a combination of both, and B) an antioxidant component comprising B1) a sterically hindered phenol antioxidant, and B2) an organophosphite antioxidant. | 2015-01-29 |
20150031808 | PHOTOSENSITIVE POLYSILOXANE COMPOSITION AND USES THEREOF - The invention relates to a photosensitive polysiloxane composition and a thin film formed by the aforementioned photosensitive polysiloxane composition. The thin film is a planarization film of a TFT substrate, an interlayer insulating film or an overcoat of a core material or a protective material in a waveguide. The invention is to provide a photosensitive polysiloxane composition having excellent surface flatness and high tapered angle of a pattern. The photosensitive polysiloxane composition comprises a polysiloxane (A), an o-naphthoquinone diazide sulfonic acid ester (B), an alkali-soluble resin containing a silyl group (C) and a solvent (D). | 2015-01-29 |
20150031809 | ANTI-VIBRATION RUBBER COMPOSITION, CROSSLINKED ANTI-VIBRATION RUBBER COMPOSITION, AND ANTI-VIBRATION RUBBER - Provided is a vibration-insulating rubber composition and a crosslinked vibration-insulating rubber composition which are excellent in low dynamic-to-static modulus ratio, elongation fatigue resistance, low temperature characteristics, and processability, and a vibration-insulating rubber using the vibration-insulating rubber composition and the crosslinked vibration-insulating rubber composition. The vibration-insulating rubber composition of the present invention includes: a rubber component having a conjugated diene compound/non-conjugated olefin copolymer, and a non-conjugated diene-based polymer; a vulcanizing agent having a bismaleimide compound; and N-phenyl-N-(trichloromethylthio)benzenesulfonamide. | 2015-01-29 |
20150031810 | Rubber Composition for Tire Including a Novel Anti-oxidant System - Rubber composition, especially for a tyre, based on at least one diene elastomer, a reinforcing filler, a crosslinking system and an antioxidant system, wherein the antioxidant system has at least two antioxidants “A” and “B”:
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20150031811 | POLYMER-CLAY NANOCOMPOSITE MATERIAL - The polymer-clay nano composite material is a nanocomposite formed from poly(styrene-co-ethyl methacrylate) copolymer and organo-modified clay by in situ polymerization. Nanoparticles of a montmorillonite clay that has been modified with a quaternary ammonium salt are dispersed into a mixture of styrene and ethyl methacrylate monomers to form a mixture, which then undergoes bulk radical polymerization. The poly(styrene-co-ethyl methacrylate) copolymer preferably has a styrene to ethyl methacrylate ratio of about 1:1. Preferably, the organically modified montmorillonite clay forms between 1.0 wt % and 5.0 wt % of the mixture. A free radical initiator, such as benzoyl peroxide, is used to initiate polymerization. The clay nano-filler provides the nanocomposite with improved thermal stability. The poly(styrene-co-ethyl methacrylate) copolymer has the structural form: | 2015-01-29 |
20150031812 | OLEFIN RESIN COMPOSITION - Provided is an olefin resin composition, and a method of manufacturing an encapsulant for an optoelectronic device, in which the encapsulant exhibits excellent adhesive strength with a back sheet and a front substrate included in various optoelectronic devices. In addition, the encapsulant does not have a bad influence on parts such as optoelectronic units or wiring electrodes encapsulated in an optoelectronic device, and a working environment, and can excellently maintain workability and economic feasibility of device manufacturing. | 2015-01-29 |
20150031813 | GREEN COALESCENT AGENT COMPOSITION CONTAINING FATTY ACID MONOESTERS OF VEGETABLE OILS WITH FUSEL OIL ALCOHOLS - The present invention is directed to compositions of green coalescents comprising monoesters obtained from direct or indirect esterification of vegetable oil fatty acids and fusel oil alcohols. The fatty acids used in the present invention have 6 to 22 carbon atoms and can be either saturated or unsaturated. | 2015-01-29 |
20150031814 | TIRE COMPRISING A COMPOSITION ESSENTIALLY FREE OF GUANIDINE DERIVATIVE AND COMPRISING AN ALKALI METAL HYDROXIDE OR ALKALINE-EARTH METAL HYDROXIDE - A tire comprising a rubber composition based on at least one diene elastomer, a reinforcing filler predominantly comprising silica, a crosslinking system, and an alkali metal hydroxide or alkaline earth metal hydroxide. The rubber composition is essentially devoid of guanidine derivative. | 2015-01-29 |
20150031815 | ESTER CARBONATE POLYOLS FOR HYDROLYTICALLY STABLE ADHESIVES - A two-component curable adhesive or sealant composition is provided. The first component may comprise a mixture of at least one polyol selected from the group comprising a polyester polyol, a polyester-polycarbonate copolymer polyol, and combinations thereof, a resin, and optionally a solvent. The second component may comprise a prepolymer obtained by reacting a polyester-polycarbonate copolymer polyol which is the reaction product of a polyester polyol which is the reaction product of one or more organic acids, and one or more glycols having a functionality of two or more and one or more polycarbonate polyols, at least one organic polyisocyanate component, and at least one chain extending agent and optionally a solvent. Alternatively, the first component may comprise a polyester-polycarbonate copolymer polyol, a resin, and optionally a solvent. The second component may comprise a polyisocyanate curative and optionally a solvent. The cured adhesive exhibits improved hydrolytic properties while maintaining excellent processability and adhesive properties. | 2015-01-29 |
20150031816 | METHOD AND APPARATUS FOR PRODUCING A NANOCOMPOSITE MATERIAL REINFORCED BY UNIDIRECTIONALLY ORIENTED PRE-DISPERSED ALUMINA NANOFIBERS - Method for producing a nanocomposite material reinforced by unidirectionally oriented pre-dispersed alumina nanofibers. The process is suited for industrial-scale production of the nanocomposite materials. The nanocomposite production process involves, synthesis of unidirectionally oriented pre-dispersed alumina nanofibers, casting a mat of pre-dispersed nanofibers with a predetermined orientation in the atmosphere of air or other gas(es) by saturating the nanofibers with liquid polymer matrix. Polymer matrix may include thermosets or/and thermoplastics. The material forming the polymer matrix may be heated to its melting point temperature to transform it to liquid phase. After saturation, the polymer matrix is hardened by lowering its temperature or by means of exposing the polymer matrix to UV radiation, electron beam and/or chemical hardeners. The nanomaterial is composed of polymer composite with homogeneously dispersed uniformly oriented reinforcing nanofibers. Subsequently, the nanofibers in the nanocomposite are dispersed by means of subjecting to hydrodynamic stress, mechanical or/and ultrasound coarse dispersing. | 2015-01-29 |
20150031817 | SEALANT - Provided is a sealant for use in contact with a polyelectrolyte membrane; at least the sealant surface contacting the polyelectrolyte membrane is constituted of a resin composition containing a crystalline polyester resin as a main component; the resin composition has a storage elastic modulus at 40° C. of 2.5 MPa or more and 5 MPa or less; the resin composition further contains an epoxy resin and an isocyanate-based crosslinking agent; and the crystalline polyester resin is crosslinked with the isocyanate-based crosslinking agent. | 2015-01-29 |
20150031818 | FIBRE REINFORCED COMPOSITE MOULDING - A method of manufacturing a moulded article and a moulding material suitable therefor comprising the steps of providing a moulding material comprising a fibrous reinforcement material, a first resin material and a second resin material, the first resin material being at least partially processed; providing the moulding material in relation to a mould to form a moulding; and processing the moulding to form the moulded article by providing energy input to the moulding. The energy input for processing the moulding to form the moulded article is less than the energy input required for processing the moulded article from a moulding. | 2015-01-29 |
20150031819 | Anticorrosion Coatings - Curable compositions comprising a benzoxazine component, a polyamine component and a fluoropolymer component are described. The compositions may be cured to produce compositions useful in coating, sealants, adhesive and many other applications. | 2015-01-29 |
20150031820 | Rubber Mixture - A rubber mixture is disclosed which is suitable in particular for vehicle pneumatic tires, belts, drive belts and hoses. The rubber mixture includes the following: at least one polar or nonpolar rubber, at least one pale- and/or dark-colored filler, at least one sulfur, which is mixed with at least one terpenoid and/or at least one high-viscosity oil, and optionally other additional substances. | 2015-01-29 |
20150031821 | RUBBER COMPOSITION AND METHOD FOR PRODUCING RUBBER COMPOSITION - The present invention provides a rubber composition comprising, as blended, a rubber component (A), an amino acid derivative (B) and a filler containing an inorganic filler (C), and further containing, as incorporated therein, at least one selected from sulfur and a sulfur compound. The vulcanization rate of the rubber composition is accelerated and the low-heat-generation property thereof is excellent. | 2015-01-29 |
20150031822 | FLUORORUBBER COMPOSITION - A fluororubber composition which includes a fluororubber (A) and a carbon black (B). The fluororubber (A) is a vinylidene fluoride-based fluororubber including a structural unit (VdF unit) derived from vinylidene fluoride and a structural unit derived from at least one monomer selected from the group consisting of hexafluoropropylene (HFP), 2,3,3,3-tetrafluoro propylene, and perfluoro(alkyl vinyl ether) (PAVE). The molar ratio of the VdF unit to the structural unit derived from at least one monomer selected from the group consisting of HFP, 2,3,3,3-tetrafluoro propylene, and PAVE is 50/50 to 78/22. The fluororubber composition has a difference δG′ (G′ (1%)-G′ (100%)) of not lower than 120 kPa and not higher than 3,000 kPa, where G′ (1%) denotes a modulus of shearing elasticity at a dynamic strain of 1%, G′ (100%) denotes a modulus of shearing elasticity at a dynamic strain of 100%, and G′ (1%) and G′ (100%) are determined by a dynamic viscoelasticity test. | 2015-01-29 |
20150031823 | Crosslinkable Composition and Method of Producing the Same - The instant invention provides crosslinkable compositions, and method of producing the same. The non-aqueous single phase crosslinkable composition comprises: (a) a polyol having an average of 2 or more hydroxyl functional groups; (b) polyaldehyde, or acetal or hemiacetal thereof; and (c) an acid catalyst having pK of less than 6; and (d) optionally one or more organic solvents. | 2015-01-29 |
20150031824 | CATALYST COMPOSITION AND METHOD FOR PREPARING THE SAME - The present invention relates to a catalyst composition for the polymerisation of olefins comprising a support containing a single site catalyst component, a catalyst activator and a modifier wherein the modifier is the product of reacting an aluminum compound of general formula AI(R1, R2, R3) with an amine compound of general formula N(R4, R5, R6). The catalyst composition reduces fouling and/or sheeting when used to catalyse the polymerisation of olefins. The present invention also relates to a method for the polymerisation of olefins using the catalyst composition of the invention. | 2015-01-29 |
20150031825 | Method Of Forming Particles From An Oil-In-Water Emulsion - Particles having an average diameter of at least 30 nanometers include a polymerization product of a silanol, a cyclic silazane, and an isocyanate. The particles are formed in an oil-in-water emulsion which includes less than 0.1 weight percent of a hydrophobic costabilizer. The particles are formed by a method including the step of reacting the silanol and the cyclic silazane and the isocyanate and the step of forming the oil-in-water emulsion. | 2015-01-29 |
20150031826 | COMPOSITIONS OF RESIN-LINEAR ORGANOSILOXANE BLOCK COPOLYMERS - A process for preparing resin-linear organosiloxane block copolymers is disclosed. The process involves an initial hydrosilylation reaction to link a linear organosiloxane block with a resin organosiloxane portion to form the resin-linear block copolymer. The resulting resin-linear organosiloxane block copolymer is further crosslinked to provide copolymer compositions that are useful as coatings for various electronics and lighting components. | 2015-01-29 |
20150031827 | POLYMER, CLATHRATE USING THE POLYMER, AND AQUEOUS DISPERSION OF SHEET OF THE POLYMER - A polymer is provided. The polymer includes a polymer chain; and a saccharide bonded with the polymer chain. The polymer does not substantially include an organic solvent and a metal atom, and includes a residual monomer in an amount of not greater than 1,000 ppm, which is relatively small compared to the amount of residual monomer in a polymer prepared by a conventional method. The polymer is preferably used for a clathrate, a sheet, and an aqueous dispersion of the sheet. | 2015-01-29 |
20150031828 | BIOBASED ALKYD RESIN AND PROCESS FOR MANUFACTURING SUCH AN ALKYD RESIN - The object of a present invention is an alkyd resin as well as the method for preparing such a resin, said alkyd resin comprising:
| 2015-01-29 |
20150031829 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THEREOF - The present invention relates to a liquid crystal alignment agent, a liquid crystal alignment film made by the liquid crystal alignment agent and a liquid crystal display element having the liquid crystal alignment film. The liquid crystal alignment agent includes a polymer (A) and a solvent (B). The polymer (A) is synthesized by reacting a mixture that includes a tetracarboxylic dianhydride compound (a) and a diamine compound (b). According to the specific diamine compound (b) and an amount of the same, the aforementioned liquid crystal alignment agent has better pretilt angle stability. | 2015-01-29 |
20150031830 | MULTIPHASE EMULSION POLYMERS FOR AQUEOUS COATING COMPOSITIONS CONTAINING LITTLE OR NO ORGANIC SOLVENTS - A multiphase emulsion polymer for aqueous coating compositions containing little or no organic solvent includes at least one soft phase and at least one hard phase prepared by a multi-stage emulsion polymerization. The hard phase contains a hard phase polymer having a glass transition temperature in a range from I0 C to 100 C which is more than 50 C higher than that of the soft phase polymer. The hard phase is formed as a first stage polymer and the one soft phase is subsequently polymerized in the presence of the first stage polymer. The hard phase polymer includes at least one carboxylic acid monomer and at least one ethylenically unstaturated monomer. A method of making a multiphase emulsion polymer for aqueous coating compositions containing zero or low levels of organic solvent is disclosed. Such aqueous coating compositions may simultaneously have excellent block resistance, freeze thaw stability and low temperature coalescence characteristics. | 2015-01-29 |
20150031831 | Polymer Compositions and Methods of Making Them - The present disclosure is directed to polymer compositions that can be useful as viscosity modifiers, comprising (a) a first ethylene-α-olefin copolymer having an ethylene content of from about 60 to about 80 wt % and (b) a second ethylene-α-olefin copolymer having an ethylene content of from about 40 to about 60 wt %. The polymer composition comprises about 35 wt % to about 50 wt of the first ethylene-α-olefin copolymer and about 50 wt % to about 65 wt % of the second ethylene-α-olefin copolymer. The polymer compositions are made by comprising producing a first ethylene-α-olefin copolymer in a first reactor, directing the first copolymer to a second reactor, producing the second ethylene-α-olefin copolymer in the second reactor and forming the polymer composition. | 2015-01-29 |
20150031832 | CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment external to the nanoparticle and related compositions, methods and systems. | 2015-01-29 |
20150031833 | FORMYLPYRROLE-BASED HETEROCYCLES FOR NUCLEIC ACID ATTACHMENT TO SUPPORTS - A compound has Formula I: | 2015-01-29 |
20150031834 | COMPOSITE POLYAMIDE FINE PARTICLES AND METHOD OF PRODUCING SAME - Composite polyamide fine particles include a polyamide (A1) which has a melting point or a glass transition temperature of over 100° C. and a polymer (A2) which is different from the polyamide (A1). The composite polyamide fine particles have: a dispersion structure in which a plurality of domains each having an average particle diameter of 0.05 to 100 μm whose main component is the polymer (A2) are dispersed in a polyamide (A1) based matrix; an average particle diameter of 0.1 to 500 μm; and a sphericity of 80 or more. | 2015-01-29 |
20150031835 | HETEROGENEOUS CATALYST AND METHOD FOR SELECTIVELY HYDROGENATING COPOLYMER UTILIZING THE SAME - Disclosed is a method for selectively hydrogenating a copolymer, including contacting a heterogeneous catalyst with a copolymer to process hydrogenation The copolymer includes aromatic rings and double bonds, and the double bonds are hydrogenated, and the aromatic rings are substantially not hydrogenated. The heterogeneous catalyst includes a metal catalyst such as platinum, palladium, platinum -iridium alloy, or platinum-rhenium alloy formed on a porous support. The hydrogenation is processed at a temperature of 40° C. to 150° C. under a hydrogen pressure of 10 kg/cm | 2015-01-29 |
20150031836 | GYPSUM DISPERSANT - There is provided a gypsum dispersant and a gypsum additive that improve the fluidity of gypsum slurry even if gypsum raw materials used are different in quality and that do not induce delay of curing of gypsum slurry. A gypsum dispersant, including: (A) a polycarboxylic acid polymer; and (B) a polyamide polyamine obtained by a reaction of a polyalkylene polyamine and a dibasic acid as essential components, and/or an alkylene oxide adduct of the polyamide polyamine. | 2015-01-29 |
20150031837 | POLYMERIC MATERIAL AND PROCESS FOR RECYCLING PLASTIC BLENDS - There is provided a polymeric material comprising: a co-continuous or highly-continuous blend of polyethylene and polypropylene, the blend comprising a polyethylene phase and a polypropylene phase separated by a polyethylene/polypropylene interface; and one or more thermoplastics other than polyethylene and polypropylene, the one or more thermoplastics each having an interfacial tension with polypropylene higher than the interfacial tension of the polyethylene/polypropylene interface, wherein the one or more thermoplastics form discrete phases that are encapsulating each other, and wherein said discrete phases are comprised within the polypropylene phase of the co-continuous or highly-continuous blend or are located at the polyethylene/polypropylene interface. There is also provided a process for recycling a blend of thermoplastics comprising polyethylene, polypropylene and one or more other thermoplastics, the process comprising the step of melting and mixing the polyethylene, the polypropylene and the one or more other thermoplastics, thereby producing a polymeric material. | 2015-01-29 |
20150031838 | METALLIC ACRYLATE SALTS TO INCREASE POLYMER MELT STRENGTH - A composition can include a polyolefin, a styrenic polymer, or a polylactic acid. The composition can include a metallic acrylate salt. A method of making a composition can include melt mixing a polyolefin, a styrenic polymer, or a polylactic acid with a metallic acrylate salt. | 2015-01-29 |
20150031839 | HYDROGENATED BRANCHED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITION AND PNEUMATIC TIRE - There is provided a hydrogenated branched conjugated diene copolymer prepared by copolymerizing 1 to 99% by weight of a branched conjugated diene compound (1): | 2015-01-29 |
20150031840 | METHOD FOR PRODUCING EPOXIDIZED NATURAL RUBBER, RUBBER COMPOSITION FOR TIRES, AND PNEUMATIC TIRE - The present invention provides a method for producing epoxidized natural rubber with high productivity and at low cost, a rubber composition for a tire containing the epoxidized natural rubber, and a pneumatic tire formed from the rubber composition for a tire. The present invention relates to a method for producing epoxidized natural rubber, the method including: step (1) of reacting an acid anhydride with hydrogen peroxide to prepare an organic peracid; and step (2) of epoxidizing natural rubber latex with the obtained organic peracid. | 2015-01-29 |
20150031841 | Compositions of Resin-Linear Organosiloxane Block Copolymers - A process is disclosed for preparing a resin-linear organosiloxane block copolymer by reacting a silanol terminated linear organosiloxane and an organosiloxane resin containing hydrolyzable groups to form a resin-linear organosiloxane block copolymer. The resulting resin-linear organosiloxane block copolymer is then crosslinked to sufficiently increase the average molecular weight of the resin-ituted organosiloxane block copolymer by at least 50%. The resin-linear organosiloxanes block copolymers prepared by the disclosed process may provide optically solid compositions which may be considered as “reprocessable.” | 2015-01-29 |
20150031842 | Methods for Polyolefin Polymerization with High Activity Catalyst Systems - A method is provided for polymerizing an olefin monomer in a reactor with a highly active polyolefin polymerization catalyst system. The method includes introducing a catalyst system comprising a catalyst and a catalyst activator into the reactor containing the olefin monomer with less than 10 seconds or no pre-contacting time of the catalyst and the catalyst activator prior to introducing the catalyst and the catalyst activator into the reactor. The catalyst system may have a standard adjusted catalyst activity of greater than 10 gPgcat | 2015-01-29 |
20150031843 | ETHYLENE POLYMERIZATION PROCESS USING AN INHIBITOR - The present invention relates to an ethylene homo- or copolymerization process, characterized in that an inhibitor is added to the reaction mixture or any of its components before the reaction mixture is fed to the reaction zone. The present invention further relates to the use of an inhibitor to reduce fouling in an ethylene homo- or copolymerization process. | 2015-01-29 |
20150031844 | NON-SUPPORTED HETEROGENEOUS POLYOLEFIN POLYMERIZATION CATALYST COMPOSITION AND METHOD FOR PREPARING SAME - Disclosed is a metallocene catalyst composition for polyolefin polymerization. The metallocene catalyst composition is in a non-supported, heterogeneous form where an ansa-metallocene is bound to a cocatalyst without a support. Also, a method for preparing the catalyst composition, and a method for preparing polyolefin using the catalyst are disclosed. Capable of readily controlling microstructures of olefin polymers in addition to having high catalytic activity, the non-supported heterogeneous catalyst composition can be applied to the preparation of polyolefin polymers at high yield without altering preexisting processes. | 2015-01-29 |
20150031845 | Process For Producing Polydienes - A method for producing a polydiene, the method comprising the steps of (i) forming an active catalyst by combining a lanthanide-containing compound, an alkylating agent, and a halogen source in the substantial absence of an organosulfide; and (ii) polymerizing conjugated diene monomer in the presence of the active catalyst and an organosulfide. | 2015-01-29 |
20150031846 | POLYMERS HAVING CHELATING FUNCTIONALITY - The present invention provides novel polymers having chelating functionality and comprising units derived from a vinyl aminocarboxylate monomer which comprises units derived from iminodiecetic acid, iminodisuccinic acid, or a salt thereof, and a vinyl epoxy benzene monomer. | 2015-01-29 |
20150031847 | METHOD OF FORMING POLYARYL POLYMERS - In a method of forming a polyacetal or polyketal, a specific acetal- or ketal-containing bis(aryl)acetal is coupled with itself or a comonomer in the presence of a catalyst and a base. The polymerization reaction tolerates hydroxyl and other functional groups on the bis(aryl)acetal. Among other applications, the polyacetals and polyketals are useful components of photoresist compositions. | 2015-01-29 |
20150031848 | POLYESTER POLYOL FOR USE IN POLYURETHANE - The present invention relates to a polyester polyol, suitable for use in the manufacture of a polyurethane, suitable for use in the manufacture of a polyurethane, the polyester polyol having an ABA-structure, in which A represents a lactide-oligomer and in which B represents an initiator. The initiator includes a reaction product having long chain dicarboxylic acid components having 18 or more carbon atoms. The invention also relates to a method for the manufacture of the polyester polyol. The invention further pertains to polyurethanes including the before-mentioned polyester polyol as well as the use of these polyurethanes as an elastomer having a high toughness. The toughness is believed to originate from the combination of the hydrophobic character of the initiator and the hydrophilic character of the lactide parts in the polyol structure. The strength of the invented polylactide-polyurethane elastomers can be further improved by incorporating a carbodiimide in the elastomer material. | 2015-01-29 |
20150031849 | POLYMER OF SULFONATED POLY(ARYLENE ETHER)S AND MANUFACTURING METHOD THEREOF - A polymer of sulfonated poly(arylene ether)s (PAEs) and a manufacturing method thereof are provided. A main structure of the PAEs has a first side formed by multi-phenyl glycol monomer and a second side formed by multi-phenyl dihalo monomer with an electron-withdrawing group. The glycol monomer and the dihalo monomer are reacted with each other by a nucleophilic displacement reaction, so as to form the main structure of the PAEs. A film made of the PAEs has a better size stability under a high water uptake. | 2015-01-29 |
20150031850 | Process for Solid-State Polycondensation - The present invention relates to a method as well as an apparatus for fixed phase polycondensation of polyesters, preferably polyethylene terephthalate and/or copolymers thereof, characterised in that the fixed phase polycondensation is performed with polyester prepolymer particles in a reaction chamber in which an absolute pressure predominates in the range from 10 mbar to 200 mbar, preferably 20 to 150 mbar, and a process gas flow in the range of an R-value of 0.005 to 0.05. | 2015-01-29 |
20150031851 | HMGN2 PEPTIDES AND RELATED MOLECULES THAT SELECTIVELY HOME TO TUMOR BLOOD VESSELS AND TUMOR CELLS - The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds the receptor bound by peptide KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK (SEQ ID NO: 9). Methods of directing a conjugate of the invention to tumor blood vessels and tumor cells and of using a conjugate to treat cancer also are provided. | 2015-01-29 |
20150031852 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE - Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or retention sequence (portion B), and (c) a linker between portion A and portion B, and (d) at least one cargo moiety. | 2015-01-29 |
20150031853 | METHOD FOR THE SELECTIVE ENRICHMENT AND LABELING OF PHOSPHORPROTEINS - The embodiments of the invention relate to a method for the introduction of a labeling structure such as a fluorescent molecules or a Raman tags to a compound. Imidazole functionalized resins or polymers are used to selectively immobilize phosphocompounds without protecting the carboxylic groups. Relying on the pKa difference between amines and hydrazides and carrying out the reaction in a slightly acidic buffer, all of the amines are protected by protonation while the hydrazides react with the phosphate imidazolide to form a phosphoramidate bond. | 2015-01-29 |
20150031854 | Novel Derivatives of Hemin with Antibacterial and Antiviral Activity - The invention relates to novel hemin derivatives of general formula (I), preparing and use thereof as antibacterial and/or antiviral agents, including, as a component in a pharmaceutical compositions. Advantages of the novel antibacterial and antiviral agents based on the hemin derivatives are in their biocompatibility, biodegradability, a high efficacy against resistant bacteria and widespread viruses which are dangerous to humans, and the lack of toxicity. | 2015-01-29 |
20150031855 | Methods for Enhancing Bacterial Cell Display of Proteins and Peptides - Methods of making and using bacterial display polypeptide libraries using circularly permuted OmpX (CPX) variants are disclosed. The invention further relates to methods for enhancing the display of proteins and peptides at the surface of bacteria by optimizing linkers and incorporating mutations at positions 165 and 166 of CPX. | 2015-01-29 |
20150031856 | Anaplastic Lymphoma Kinase (ALK) As An Oncogene Capable Of Transforming Normal Human Cells - The present invention provides compositions and methods for transforming primary mammalian cells using an oncogenic form of ALK wherein the transformed cells display features of that of a corresponding tumor cell isolated from a cancer subject. The invention also provides a method for immortalizing normal CD4+ T lymphocytes with a lymphoma-characteristic form of ALK such as NPM-ALK. | 2015-01-29 |
20150031857 | DENGUE SEROTYPE 2 ATTENUATED STRAIN - The invention relates to live attenuated VDV2 (VERO-Derived Vaccine Dengue serotype 2) strains which have been derived from the wild-type dengue-2 strain 16681 by passaging on PDK and Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV2 strain. | 2015-01-29 |
20150031858 | Methods of Stimulating Protective Immunity Employing Dengue Viral Antigens - Compositions that include at least a portion of at least one pathogen-associated molecular pattern and at least a portion of at least one member selected from the group consisting of a Den1 viral envelope protein, a Den2 viral envelope protein, a Den3 viral envelope protein and a Den4 viral envelope protein are employed in methods to stimulate a protective immune response in a subject. | 2015-01-29 |
20150031859 | USE OF NEW RECOMBINANT INTERFERONS WITH ALTERED SPATIAL CONFIGURATION AND THREE-DIMENSIONAL STRUCTURE - This invention provides a crystalline recombinant interferon (rSIFN-co) having (i) the same amino acid sequence as that of human consensus interferon, and (ii) altered three-dimensional structure as compared to IFN-α2b. The interferon of the present invention exhibits enhanced biological activities. The present invention also provides a structure model of said interferon useful for drug screening and/or drug design and the mimetic of said interferon. The invention further provides methods of designing and using new recombinant interferons with altered spatial configuration and three-dimensional structure. | 2015-01-29 |
20150031860 | HUMAN ANTIBODIES AND PROTEINS - The present invention provides composite proteins, including antibodies, which show reduced immunogenicity. In particular, composite antibodies for use in humans are provided, in particular antibodies which have been modified to remove one or more T-cell epitopes. Methods for generating such proteins are also provided. | 2015-01-29 |
20150031861 | Chemical Modification of Antibodies - The present invention relates to antibodies and antibody fragments, one or more of whose native inter-chain disulfide bridges have been replaced with a specific bridging moiety. The bridging moiety can be selectively targeted to inter-chain disulfide bonds within the antibody or antibody fragment, enabling the construction of more homogenously modified products such as antibody-drug conjugates. | 2015-01-29 |
20150031862 | OPTIMIZED Fc VARIANTS - The present invention relates to Fc variants having decreased affinity for FcγRIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants. | 2015-01-29 |
20150031863 | CONJUGATING AMINES - The disclosure provides directly conjugated polysaccharide vaccine molecules and methods related thereto. | 2015-01-29 |
20150031864 | Modified Adiponectin Polypeptides and Their Uses - Modified adiponectin polypeptides and uses thereof are provided. | 2015-01-29 |
20150031865 | PROCESS FOR THE PRODUCTION OF FONDAPARINUX SODIUM - The present invention provides novel processes for the preparation of Fondaparinux sodium by using the compound of formula ABC5 | 2015-01-29 |
20150031866 | PROCESS FOR THE PRODUCTION OF FONDAPARINUX SODIUM - The present invention provides improved processes of preparing Fondaparinux sodium comprising converting a compound of formula ABCDE4 to Fondaparinux sodium at a reaction pH of no more than about 9.0. In some embodiments, the intermediates for the synthesis of Fondaparinux sodium, are also provided. | 2015-01-29 |
20150031867 | WATER-SOLUBLE FLUORESCENCE COMPOUND AND METHOD FOR PREPARING THE SAME - The present invention provides a water-soluble fluorescent compound of resveratrone 6-O-β-glucoside [(E)-4-(8-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)naphthalen-2-yl)but-3-en-2-one] and its derivatives of Formula 1 which have at least one water-soluble substituent, and a method for preparing the same by a photochemical reaction of resveratrol 3-O-β-glucoside and its derivatives of having Formula 3 which are not fluorescent. Said new water-soluble fluorescent compounds has single-photon absorptive characteristics and/or two-photon absorptive characteristics as well as no or little toxicity, and can be usefully utilized in fields that requires water-soluble fluorescent characteristics (diagnosis, fluorescent probe, in vivo imaging, display, etc.). | 2015-01-29 |
20150031868 | DITERPENE PRODUCTION - The present invention relates to a recombinant microorganism comprising one or more nucleotide sequence(s) encoding: a polypeptide having ent-copalyl pyrophosphate synthase activity; a polypeptide having ent-Kaurene synthase activity; a polypeptide having ent-Kaurene oxidase activity; and a polypeptide having kaurenoic acid 13-hydroxylase activity, whereby expression of the nucleotide sequence(s) confer(s) on the microorganism the ability to produce at least steviol. The recombinant microorganism may also be capable of expressing one or more UDP-glucosyltransferases such that the microorganism is capable of producing one or more steviol glycosides. | 2015-01-29 |
20150031869 | HIGH-PURITY STEVIOL GLYCOSIDES - Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and X are described. The method includes expression of UDP-glucosyltransferases from | 2015-01-29 |
20150031870 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 2015-01-29 |
20150031871 | RNA-Mediated Gene Modulation - An isolated RNA comprising an intron RNA that is released in a cell, thereby modulating the function of a target gene. Also disclosed are a composition comprising a chemokine and an isolated RNA of the invention or a DNA template for the isolated RNA, a composition comprising one or more agents that induce RNA-mediated modulation of the functions of two or more target genes in a cell, and methods of using these compositions for modulating the functions of genes in a cell. | 2015-01-29 |
20150031872 | METHOD FOR SCREENING ANTICANCER DRUGS, AND ANTICANCER DRUG THAT INDUCES CELL DEATH AND USES SUBSTANCE THAT INCREASES GRANZYME M ACTIVITY AS ACTIVE INGREDIENT - The purpose of the present invention is to provide a method for screening anticancer drugs that use novel treatment mechanisms, and an anticancer drug that induces cell death and uses a substance that increases the activity of granzyme M as an active ingredient. This method for screening anticancer drugs comprises: a step for administering test substances to cancer cells; a step for detecting the activity of granzyme M in which cancer cells are expressed, and selecting test substances for which an increase in activity has been verified; and/or a step for detecting the presence or absence of cancer cell death induced by the activation of granzyme M in which cancer cells are expressed, and selecting test substances for which cell death has been verified. | 2015-01-29 |
20150031873 | PROCESS OF PREPARING AN ESTER OF A CELLULOSE ETHER - A reaction product mixture is obtained from a reaction of (a) a cellulose ether with (b) an aliphatic monocarboxylic acid anhydride or with a di- or tricarboxylic acid anhydride or with a combination of an aliphatic mono-carboxylic acid anhydride and a di- or tri-carboxylic acid anhydride in the presence of (c) an aliphatic carboxylic acid. A process for precipitating an esterified cellulose ether from this reaction product mixture comprises the step of contacting the reaction product mixture with water and subjecting the combination of water and the reaction product mixture to a shear rate of at least 800 s | 2015-01-29 |