05th week of 2021 patent applcation highlights part 38 |
Patent application number | Title | Published |
20210033574 | Apparatus for Processing a Liquid Comprising a Target Substance - Apparatus for processing a liquid comprising a target substance, preferably a biomolecule, is provided. The apparatus comprises at least a first and a second means for carrying out a unit operation, each means for carrying out a unit operation comprising a feed for a liquid in fluid connection with the inlet of a flow-controller comprising a variable flow inlet valve and an outlet, wherein at least one of the means for carrying out a unit operation comprises feeds for at least two liquids, the feeds being in fluid connection with the inlets of a multiple inlet flow-controller comprising two or more variable flow inlet valves for dosing the at least two liquids, the flow-controller also comprising an outlet; a feed for a liquid feedstock comprising the target substance in fluid connection with the outlet from the flow-controller thereby to enable combination of the feed for a liquid comprising the target substance with the mixed bioprocessing liquids to produce a device feed; a device for achieving a processing operation comprising a device inlet and a device outlet, the device inlet being in fluid connection with the device feed; and a means for imparting flow through the flow controller and from the feed for the liquid feedstock through the processing device via the device inlet; and wherein the feed for a liquid feedstock comprising the target substance for the second means for carrying out a unit operation comprises the outlet from the first means for carrying out a unit operation. | 2021-02-04 |
20210033575 | Determination and Correction of Retention Time and Mass/Charge Shifts in LC-MS Experiments - Methods are described for the automatic determination and correction of retention time shift of a MS data set relative to a control data set, to correct for retention time drifts endemic to targeted LCMS analyses. In an embodiment, a 2D grid of periodic MS spectra versus time is collected for a control experiment, and RT windows are determined with an additional set of unscheduled mass spectral analyses. During successive experiments, spectra from periodic MS scans are used to determine the correspondence between the current time and the time in the control experiment. The active set of MSn scans to be acquired by the instrument is then determined as the scans with adjusted retention time windows that bracket the corrected retention time. | 2021-02-04 |
20210033576 | ANALYZING DATA COLLECTED BY ANALYTICAL INSTRUMENTS - The present disclosure describes a method, a system, and a computer program product of analyzing data collected by analytical instruments. In an embodiment, the method, the system, and the computer program product include receiving set-up information, running at least one incomplete analytical method on at least one known sample on at least one analytical instrument with respect to the set-up information, resulting in known sample data, processing the at least one incomplete analytical method with respect to the known sample data, resulting in at least one validated analytical method, and running the at least one validated analytical method on at least one unknown sample on the at least one analytical instrument with respect to the set-up information, resulting in analyzed sample data. | 2021-02-04 |
20210033577 | Method for Ranking Library Hits in Mass Spectrometry - A method for ranking analytes includes the steps of analyzing an experimental analyte in a mass spectrometer. The method includes comparing the experimental analyte to a plurality of candidate analytes in a library hit list, and assigning a cumulative confidence score to each candidate analyte based on the steps of comparing the experimental analyte to the candidate analytes based on a library similarity score, comparing the experimental analyte to the candidate analytes based on of a presence of the most abundant isotope of a molecular ion and its mass, comparing the experimental analyte to the candidate analytes based on an abundance of fragment ions and a mass of the fragment ions, and, in some implementations, comparing the experimental analyte to the candidate analytes based on a retention index value. The method includes ranking the candidate analytes based on the cumulative confidence score of each candidate analyte. | 2021-02-04 |
20210033578 | MODIFIED RESINS AND USES THEREOF - Modified thermoplastic hydrocarbon thermoplastic resins are provided, as well as methods of their manufacture and uses thereof in rubber compositions. The modified thermoplastic resins are modified by decreasing the relative quantity of the dimer, trimer, tetramer, and pentamer oligomers as compared to the corresponding unmodified thermoplastic resin polymers, resulting in a product that exhibits a greater shift in the glass transition temperature of the elastomer(s) used in tire formulations. This translates to better viscoelastic predictors of tire tread performance, such as wet grip and rolling resistance. The modified thermoplastic resins impart remarkable properties on various rubber compositions, such as tires, belts, hoses, brakes, and the like. Automobile tires incorporating the modified thermoplastic resins are shown to possess excellent results in balancing the properties of rolling resistance, tire wear, snow performance, and wet braking performance. | 2021-02-04 |
20210033579 | SULFATE DETECTION WITH BARIUM - An embodiment provides a method for measuring sulfate in an aqueous sample, including: introducing an aqueous sample containing an amount of sulfate to a barium dye complex, thereby creating a solution; adding a clarifying agent to the solution, thereby causing the solution to be clarified; and measuring the amount of sulfate in the aqueous sample by measuring a change in color of the solution, the change in color caused by the barium dye complex mixing with the sulfate. Other aspects are described and claimed. | 2021-02-04 |
20210033580 | PASSIVE CHRONOMETRIC TAMPER-INDICATING DEVICE AND METHOD - A tamper-indicating device, the tamper-indicating device including: an elongate structure; a penetrant chamber coupled to the elongate structure; and a physical barrier (or other release mechanism) disposed between the elongate structure and the penetrant chamber; wherein the penetrant chamber is adapted to contain a penetrant material that selectively diffuses into the elongate structure at a predetermined rate when the physical barrier is ruptured (or the other release mechanism is actuated) by a tamper or environmental event; and wherein the penetrant material creates an overt or covert indication of the degree of diffusion into the elongate structure, the degree of diffusion indicating an amount of time since the tamper or environmental event. The tamper-indicating device further includes a substrate coupled to the elongate structure. Optionally, the tamper-indicating device further includes a visible time scale disposed on the substrate substantially adjacent to the elongate structure. | 2021-02-04 |
20210033581 | MEASURING SYSTEM AND MEASURING METHOD OF HYDROGEN PEROXIDE CONCENTRATION - Provided are a method and system for measuring hydrogen peroxide concentration in sample water collected from a prescribed position in a water treatment process and includes: collecting the sample water; measuring a concentration of a dissolved oxygen in the sample water or a treated water obtained by treating the sample water with the hydrogen peroxide decomposing device by first and second dissolved oxygen concentration measuring analyzers to obtain a corrected value that is a difference between the two dissolved oxygen concentration values; measuring the concentration of the dissolved oxygen in the sample and treated water by the first and second dissolved oxygen concentration measuring analyzers, respectively, and obtaining a measured value that is a difference between the dissolved oxygen concentration values; and calculating a corrected concentration of hydrogen peroxide from the measured value obtained during the measured value obtaining and the corrected value obtained during the corrected value obtaining. | 2021-02-04 |
20210033582 | SYSTEM AND METHOD FOR SCENT PERCEPTION MEASUREMENTS AND FOR CONSTRUCTION OF A SCENT DATABASE - A system and method for creating a scent database is described. An electronic sensing unit is used to receive an odorant sample and generate an electronic signature characterizing the sample received therein via a guiding unit that guides a first portion of the sample into an electronic sampling unit and a second portion of the sample towards an outlet. A control unit is used to receive data indicative of the signature generated by the sensing unit and data from user(s) indicative of olfactive descriptors characterizing the sample to which the users are exposed, enabling creation of a data record including first and second data corresponding to the same sample. The database includes data, each associated with a specific odorant sample, which may be used to characterise/formulate/create, a desired scent based on comparison of an electric signature generated for the scent and data records which signatures comply with best compliance criterion. | 2021-02-04 |
20210033583 | Systems and Methods for Improving Detection Accuracy in Electronic Trace Detectors - Embodiments of the present specification provide methods and systems for maintaining accuracy and precision of calibration for a detector. The methods and systems include reducing the humidity of an internal calibration assembly by directing flow path of dry air periodically through the internal calibration assembly. | 2021-02-04 |
20210033584 | MOBILE MEASURING DEVICE, SYSTEM AND PROCESS FOR A SAFETY-RELEVANT APPLICATION - A safety application mobile measuring device ( | 2021-02-04 |
20210033585 | Continuous Sonic Wave Analyzer - A gas analyzer uses continuous sonic signals through a conduit to determine the composition of a gas in the conduit. A transmitting transducer drives sonic signals at a fixed frequency and a second transducer receives the sonic signals. The phase shift between two signals corresponds to the speed of sound through the gas and is related to the composition of the gas. The electronic versions of these signals are processed by lowering, or dividing, the fixed frequency which expands the range of phase shift measurement and allows the determination of an expanded range for the gas composition. In an ozone generation system, the gas analyzer is highly suitable for determining the composition of gases derived from air as a gas of known composition and a calibration point. | 2021-02-04 |
20210033586 | WIRELESS EXPOSURE MONITOR - Systems, apparatuses, and methods for monitoring an environment are provided. One system includes a monitoring unit positioned within an environment and including an acoustic sensor configured to generate detected acoustic data regarding acoustics in the environment, and a controller having one or more processors and one or more non-transitory memory devices that store instructions for controlling the one or more first processors to receive and store the detected acoustic data, determine, based on the detected acoustic data, whether a noise is above a threshold, and determine, based on the detected acoustic data and that the noise is above the threshold, an estimated source of the noise. | 2021-02-04 |
20210033587 | SYSTEMS AND METHODS FOR REPORTING PERFORMANCE OF AGRICULTURAL INPUTS - A computer-implemented method for reporting performance of an agricultural input for a plant involves: storing in a computer database a set of agricultural inputs, plants for which the agricultural inputs are used, performance attributes of the agricultural inputs, historical agricultural input performance values, and a relative significance of each of the agricultural inputs for the performance attribute. A computer processor is used to receive a plant selection; receive an attribute to be targeted for the plant selection; identify a plurality of agricultural inputs for affecting the targeted attribute for the plant using the historical agricultural input performance values; rank the plurality of agricultural inputs for affecting the targeted attribute for the selected plant using the relative significance associated therewith; and display the plurality of agricultural inputs and corresponding ranks for the received attribute associated with the selected plant. | 2021-02-04 |
20210033588 | APPARATUS BUFFER AND METHOD FOR PH CONTROL - An apparatus, buffer solutions and a method are provided for pH control of in vitro dissolution tests used to monitor the drug release rate from solid unit dosage forms which are used to predict their in vivo effects or for quality control purposes. A method of preparing a continuous condition and a clear bicarbonate ion based solution for in vitro dissolution testing of pharmaceutical products is also provided. | 2021-02-04 |
20210033589 | HYPERSPECTRAL SENSING SYSTEM AND METHODS - A method for retrieving a corrected spectrum from a measured spectrum (e.g., retrieving a top-of-water spectrum from a measured top-of-atmosphere spectrum) includes creating a scene-specific model of a region of interest and performing a ray-tracing simulation to simulate rays of light that would reach an airborne (or spaceborne) sensor. The region of interest can be an optically complex area such as an inland or coastal body of water. Based on the ray-tracing simulation, a scene-specific correction for unwanted effects (e.g., adjacency effects, variable atmospheric conditions, and/or other suitable effects) is obtained. A corrected spectrum is obtained by correcting the measured spectrum using the scene-specific correction. The ray-tracing simulation may be performed using a graphical processing unit, allowing the scene-specific correction to be performed in real time or near real time. | 2021-02-04 |
20210033590 | METHOD FOR DETERMINING A CHEMICAL INTAKE CAPACITY OF A PROCESS MEDIUM IN A MEASURING POINT AND MEASURING POINT FOR DETERMINING A CHEMICAL INTAKE CAPACITY OF A PROCESS MEDIUM - A method for determining a chemical intake capacity of a process medium includes steps of providing a measuring point and an analytical measuring device, closing an outlet valve to the drain so that no process medium is discharged and closing the inlet valve so that no additional process medium is fed from the first inlet. The method includes circulating the analyte and process medium through the pump so the mixture flows into the analytical measuring device at a predetermined flow velocity. Further, the method includes detecting a measured value using the analytical measuring device until the measured value exceeds a limit value. The predetermined volumes are summed to form a total volume of the analyte, and a chemical intake capacity of the predetermined medium is determined based on the total volume of the analyte fed in. | 2021-02-04 |
20210033591 | NANOPORE PROTEIN CONJUGATES FOR DETECTION AND ANALYSIS OF ANALYTES - Provided are methods, compositions, and systems for the detection of a target analyte. Also provided are methods, compositions, and systems for determining the concentration one or more target analytes in fluid solution. The compositions include nanopore conjugates in which a nanopore protein monomer is joined to a capture tag. Tethered to the nanopore protein conjugate is an analyte ligand directed to a specific analyte. When a voltage is applied across a nanopore assembly including the nanopore conjugate, the nanopore captures the capture tag at a given capture rate. In the presence of the analyte to the analyte ligand, however, the capture rate of the capture tag changes, thus permitting detection of the analyte by the nanopore assembly. Further, based on the capture rate associated with binding between the analyte and the analyte ligand, the concentration of the analyte can be determined using association/dissociation kinetics. | 2021-02-04 |
20210033592 | BLOOD ANALYZER AND ANALYSIS METHOD - A blood analyzer and a blood analysis method thereof are provided. The blood analyzer includes a test sample preparation apparatus, a flow chamber, a measurement apparatus and a data processor. The method adopts a white blood cell measurement channel to detect a test blood sample subjected to hemolysis and fluorescence staining and utilizes data in a blood ghost region to identify reticulocyte particles, thereby realizing differentiation of reticulocytes and large platelets and realizing finer classification and count of reticulocytes without separately designing an optical detection channel in the blood analyzer. A computer readable storage medium is also disclosed, in which a program is stored, and the program can be executed by the data processor to implement the above method. | 2021-02-04 |
20210033593 | METHODS AND SYSTEMS FOR DETERMINING PLATELET CONCENTRATION - Disclosed are a method for determining a platelet concentration of a blood sample, a hematology system ( | 2021-02-04 |
20210033594 | METHODS FOR DIAGNOSIS AND INTERVENTION OF HEPATIC DISORDERS - The disclosure provides a method for quantification of hepatic function in a subject comprising measuring the clearance of an orally administered isotopically labeled cholic acid in a subject with, or suspected of having or developing, a hepatic disorder, for example, chronic hepatitis C. The disclosure further provides methods and kits for assessment of hepatic function. | 2021-02-04 |
20210033595 | Methods and Compositions for Treating Diseases Associated with Exhausted T Cells - The present invention provides compositions and methods for detecting exhausted T cells in a subject. The present invention also provides methods for treating a subject having a disease characterized by the presence of exhausted T cells or certain subpopulations thereof. | 2021-02-04 |
20210033596 | Methods for High-Content Drug Screening - Provided herein are methods and systems for screening a candidate agent to determine whether the candidate agent modulates an activity of cultured cells. Compositions for screening a candidate agent are also provided herein. | 2021-02-04 |
20210033597 | METHOD FOR IDENTIFYING EFFECTIVE TREATMENTS AGAINST NEURODEGENERATIVE DISORDERS - The present invention relates to systems and methods for reprogramming cells to generate neurons and identifying effective treatments for neurodegenerative disorders using such neurons, as well as systems and methods for treating and developing treatments for one or more neurodegenerative disorders. | 2021-02-04 |
20210033598 | Detection Device - The present invention provides a detection device comprises a testing element and a transparent area, wherein the testing element comprises a test area which is configured to detect a presence of an analyte in a liquid sample; the transparent area is configured to read the test result on the test area through the transparent area; a part of the transparent area contacts a part of the detection area, or the detection area and the transparent area are arranged in one sealed space, thus to make the air in the sealed space not exchange with the air outside the sealed space; the scheme can reduce the mist to ensure the test result is displayed clearly. | 2021-02-04 |
20210033599 | INFORMATION PROCESSING APPARATUS, CONTROL METHOD, AND PROGRAM - An information processing apparatus ( | 2021-02-04 |
20210033600 | Methods for Quantifying IL-33 - Methods and compositions for detecting and quantifying cytokines are provided. The disclosed assays have reduced assay interference relative to commercially available assays and/or a control assay. The interference can be cytokine dependent, cytokine independent, or both. One embodiment provides an IL-33 immunoassay that reduces assay interference caused by endogenous soluble IL-33 binding molecules present in the sample. Exemplary soluble IL-33 binding molecules include, but are not limited to anti-IL-33 antibodies, soluble ST2 receptor, and serum components. In some embodiments a blocking agent is added to the sample to reduce, inhibit, or block IL-33 complexes in the sample from reforming after acid dissociation of the IL-33 complexes in the sample. In one embodiment, the blocking agent and the detection reagent do not compete for binding to IL-33. | 2021-02-04 |
20210033601 | TESTING DEVICE AND METHOD FOR PRODUCING SAME, TESTING METHOD, AND TESTING KIT AND TRANSFER MEDIUM FOR PRODUCING TESTING DEVICE - Provided is a testing device including: a porous flow path member constituting a flow path through which a testing target liquid is flowed; a testing target liquid dropping portion provided on the flow path member; a labeling portion configured to apply a label to a target nucleic acid when the target nucleic acid is contained in the testing target liquid dropped onto the testing target liquid dropping portion; and a detecting portion configured to detect the target nucleic acid labeled at the labeling portion, wherein the testing device includes a shaped body formed of a resin on the flow path member at the detecting portion, and wherein a capture nucleic acid including a sequence bindable and complementary with the target nucleic acid is immobilized by covalent binding to a surface of the shaped body between the shaped body and the flow path member. | 2021-02-04 |
20210033602 | Simplifying Solid-Phase Microextraction (SPME)-Based Analytical Measurements of Exceedingly Small-Volume Samples by Application of Negligible Depletion - This invention discloses an approach regarding the use of solid-phase microextractions (SPMEs) in the analytical, bioanalytical, combinatorial sciences, and all other applicable areas of measurement science. The approach applies to the analysis of exceedingly small volumes of a liquid specimen (10s-100s of μL), and how the concepts of negligible depletion (ND) can be used within the context of tradeoff between extractive (reaction) kinetics, extractive capacity, and sample flow rate as a means to obviate the need to deliver accurately a small volume sample for SPME analysis, improving the ease-of-use for a number of different SPME-based measurements including, for example, disease markers in immunoassays for health care. | 2021-02-04 |
20210033603 | BIOSENSOR USING MAGNETIC NANOPARTICLES, AND DETECTION DEVICE AND DETECTION METHOD USING SAME - According to one embodiment of the present application, a biosensor, the biosensor comprising: a reaction part including a magnetic nanoparticle complex, a first electrode, and a second electrode; and a sample introduction part forming a passage so that a sample can be introduced into the reaction part from an outside of the biosensor; wherein the magnetic nanoparticle complex includes a first capturing substance for capturing a first target substance, a magnetic nanoparticle, and a reaction substance that performs at least one of an oxidation reaction and a reduction reaction, wherein the magnetic nanoparticle complex has is magnetic in the reaction part, and has a property that mobility can be changed according to a change in a condition of the reaction part, wherein the first electrode, a second capturing substance for capturing a second target substance is fixed, wherein the second electrode is an electrode different from the first electrode, and characterized in that at least one of the first target substance and the second target substance is included in the sample, may be provided. | 2021-02-04 |
20210033604 | MATERIALS AND METHODS FOR IMPLEMENTING IMMUNOASSAY ON MICRONEEDLE PATCH FOR DETECTION AND QUANTIFICATION OF BIOANALYTES IN INTERSTITIAL FLUID - The present disclosure is directed to microneedle patches for direct sampling and ultrasensitive detection of protein biomarkers in dermal interstitial fluids. The microneedle patches are comprised of polymers with high protein absorption capability (e.g. polystyrene) and are modified with capture biorecognition elements that are specific to target analytes in the interstitial fluid (ISF). Systems and methods are further provided for detection of a target ISF analyte obtained by in vivo sampling of the ISF using a microneedle patch. | 2021-02-04 |
20210033605 | LATERAL FLOW IMMUNOASSAY STRIP DEVICE - The invention relates to a lateral flow assay device for the detection of a target peptide in a liquid sample, comprising: (a) a solid support, (b) a sample pad for initially receiving and optionally pre-treating the sample at a first end of the solid support, (c) an absorbent pad at a second end of the solid support, (d) a conjugate pad comprising in a dry state a mobilizable conjugate of a particle and the target peptide, wherein the target peptide conjugated to said particle is biotinylated and the particle comprises on its surface a biotin-binding protein, (e) a target peptide reaction membrane comprising, (i) a capture region comprising an immobilized first capture reagent against the target peptide, and (ii) optionally a control region comprising an immobilized second capture reagent against particle control conjugate, wherein the sample pad, the conjugate pad, the reaction membrane and the absorbent pad are mounted to the solid support to permit capillary flow from the sample pad to the reaction membrane through the conjugate pad, and wherein the loading of the particle with the target peptide is from about 20% to about 55% of the maximal loading capacity of the particle. | 2021-02-04 |
20210033606 | DNA mapping and sequencing on linearized DNA molecules - The present invention provides novel methods for immobilizing and/or optically mapping oligonucleotides, the method comprising immobilizing the oligonucleotides on a micropatterned substrate. In another aspect, the invention provides a method for mapping a genome, wherein the method is capable of resolving a single nucleotide polymorphism (SNP), the method comprising introducing to the genome a CRISPR/Cas9 system comprising at least one single-guide RNA (sgRNA) specific for a target sequence or a plurality of target sequences across the genome and a Cas9 D10A, wherein the CRISPR/Cas9 system nick labels the target sequence, and the target sequence or genome is analyzed. | 2021-02-04 |
20210033607 | DIAGNOSTIC TEST - The method according to the invention enables the confirmation of infections/carriage caused by | 2021-02-04 |
20210033608 | Methods and Systems for Identification of Human Leukocyte Antigen Peptide Presentation and Applications Thereof - Processes and computational frameworks to determine major histocompatibility complex (MHC) presentation of peptides are described. Peptides of varying length can be queried to determine the likelihood that the peptide would be presented on MHC I or MHC II. Peptides determined to be presented can be utilized in various downstream applications. | 2021-02-04 |
20210033609 | AN IMMUNOASSAY FOR THE DIAGNOSIS OF VIRAL INFECTIONS - A recombinant polypeptide can be used in the diagnosis of the presence of a Zika virus in a patient. The recombinant polypeptide includes SEQ ID NO: 1 or a variant thereof. The recombinant peptide may be a monomer, a dimer, or a hexamer. | 2021-02-04 |
20210033610 | INTRACELLULAR NITRIC OXIDE AS A BIOMARKER FOR INCREASED SUSCEPTIBILITY SYSTEMIC INFLAMMATION - Methods and kits are provided for identifying subjects at increased risk for IgE mediated systemic inflammatory disorders, particularly asthma. | 2021-02-04 |
20210033611 | METHODS AND COMPOUNDS FOR DIAGNOSING THREONYL-tRNA SYNTHETASE-ASSOCIATED DISEASES AND CONDITIONS - The invention includes, in part, methods and compounds for diagnosing diseases and conditions characterized by altered threonyl-tRNA synthetase (TARS) activity, which include, but are not limited to diseases and conditions in which angiogenesis is altered. In some embodiments of the invention, a level of a TARS molecule is determined and compared to a control level of TARS to assess onset, progression, and/or regression of a disease or condition associated with altered TARS activity. | 2021-02-04 |
20210033612 | METHODS OF USING NON-RARE CELLS TO DETECT RARE CELLS - The invention provides seminal computational approaches utilizing data from non-rare cells to detect rare cells, such as circulating tumor cells (CTCs). The invention is applicable at two distinct stages of CTC detection; the first being to make decisions about data collection parameters and the second being to make decisions during data reduction and analysis. Additionally, the invention utilizes both one and multi-dimensional parameterized data in a decision making process. | 2021-02-04 |
20210033613 | METHODS OF TREATING MULTIFOCAL CANCER - The embodiments include methods of treating (preventing or reducing the incidence of) multifocal cancer by administering to a unifocal cancer focus a composition comprising a therapeutically effective amount of a therapeutically effective amount of pharmaceutically active ingredient capable of inducing necrosis of the unifocal cancer tumor, wherein administration reduces multifocal cancer incidence, multifocal cancer grade, and multifocal cancer progression (worsening) in the entire organ or organism. | 2021-02-04 |
20210033614 | SERUM-BASED BIOMARKERS OF PANCREATIC CANCER AND USES THEREOF FOR DISEASE DETECTION AND DIAGNOSIS - Biomarkers of pancreatic cancer are described, as well as methods using these compounds for detecting pancreatic cancer. The methods can be used to diagnose a patient's health state, or change in health state, or for diagnosing risk of developing or the presence of pancreatic cancer. The method comprises analyzing a sample from a patient to obtain quantifying data for one or more than one of the metabolite markers; comparing the quantifying data to corresponding data obtained for one or more than one reference sample to identify abnormalities in the level of the metabolite marker(s) in the sample; and making a diagnosis if an abnormality is observed. Standards and kits for carrying out the method are also described. | 2021-02-04 |
20210033615 | SCREENING METHOD FOR THE IDENTIFICATION OF CANCER THERAPEUTICS - The present invention pertains to a method for identifying anti-cancer compounds. The invention is based on the finding that a direct protein-protein interaction between 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4) and (F-box protein 28) FBXO28 silences a ubiquitin E3 ligase activity of FBXO28 towards HIF1 | 2021-02-04 |
20210033616 | L2A5 ANTIBODY OR FUNCTIONAL FRAGMENT THEREOF AGAINST TUMOUR ANTIGENS - This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. | 2021-02-04 |
20210033617 | CELL LABELING AGENT AND CELL LABELING KIT - The cell labeling agent includes a monosaccharide derivatives with a six-membered ring structure that are metabolized to sialic acid in the sialic acid biosynthetic pathway of cells. Among the groups bonded to carbon atoms constituting a six-membered ring in the monosaccharide derivatives, at least one group that does not change, even when metabolized by the sialic acid biosynthetic pathway, includes a ring structure with a carbon-carbon double bond or triple bond. | 2021-02-04 |
20210033618 | BIOLOGICAL STATUS CLASSIFICATION - There is provided a method of classifying a biological status of an individual. The method comprising: obtaining a biological sample from a patient; obtaining health-related information from the patient, said information including patient gender; analysing the sample to identify a quantity of each of 2 or more endogenous analytes in the sample; comparing the analyte quantities to reference data from healthy individuals to classify the patient as healthy, pre-diseased, at risk of disease or diseased for at least one health-related condition. The reference data includes data derived from a group of biological samples of individuals having the same gender as the patient and not having a need for medical treatment for a disease or illness, each biological sample of the group of biological samples having been analysed by the same process as used to analyse the patient sample, the process being monitored to maintain a predetermined level of consistency. | 2021-02-04 |
20210033619 | METHODS OF PREDICTING PRE TERM BIRTH FROM PREECLAMPSIA USING METABOLIC AND PROTEIN BIOMARKERS - A computer implemented method of early prediction of risk of a pregnancy outcome in a pregnant woman, comprising the steps of: inputting into a computational model values for a panel of a plurality of preeclampsia specific biomarkers comprising at least one metabolite, and optionally at least one protein or clinical risk factor, selected from Table 1, in which the values are obtained from the pregnant woman early in pregnancy; selecting a subset of inputted values comprising a value for at least one metabolite and optionally at least one protein or clinical risk factor value, based on a selected pregnancy outcome selected from pre-term preeclampsia, term preeclampsia and all preeclampsia; calculating a predicted risk of the selected pregnancy outcome based on the subset of inputted values; and outputting the predicted risk of the pregnancy outcome for the pregnant woman. | 2021-02-04 |
20210033620 | Immobilized Enzymatic Digestion of Blood Products for Diagnostic Testing - This invention discloses a pretreatment approach for blood and bodily fluids to remove unwanted protein interferences in the measurement of analytes. Enzymes either contained in a cartridge or immobilized on a solid support break down proteins that complex with the analyte to shield it from detection. This pretreatment significantly enhances the detectability of analytes and does not require subsequent clean-up steps that would normally be required to ensure the functionality of the analysis method, thereby, creating a simple yet powerful approach for sample pretreatment in a variety of settings ranging from a complex laboratory infrastructure to a field deployable application. | 2021-02-04 |
20210033621 | METHODS FOR DIAGNOSING AN AUTISTIC SPECTRUM DISORDER - The present invention provides methods for diagnosing an autistic spectrum disorder (ASD), comprising detecting the concentration of an amino acid adduct in a sample obtained from a subject, wherein said amino acid adduct is a glycated amino acid adduct, an oxidised amino acid adduct, or a nitrated amino acid adduct. Methods of the invention further comprise comparing the concentration of the amino acid adduct in the sample with the concentration of the same amino acid adduct in a reference standard; and identifying the presence or absence of a concentration difference of said amino acid adduct in the sample relative to the reference standard; wherein the presence or absence of a concentration difference correlates with the presence or absence of ASD. Diagnostic algorithms for use in methods of the invention are also provided. | 2021-02-04 |
20210033622 | IMPROVED METHODS FOR IMMUNOAFFINITY ENRICHMENT AND MASS SPECTROMETRY - This disclosure relates to the field of mass spectrometry analysis. In some embodiments, the disclosure relates to methods for detecting and quantifying proteins by enrichment followed by mass spectrometry analysis. | 2021-02-04 |
20210033623 | TISSUE ANALYSIS BY MASS SPECTROMETRY - Methods and devices are provided for assessing biological samples using molecular analysis. In certain aspects, methods and devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry. In certain aspects, the results of the mass spectrometry can be analyzed to determine tissue type, sample quality, or disease state of the sample. | 2021-02-04 |
20210033624 | Online Measurement of Titer in Antibody Production - The present invention relates to a device and method capable of rapid and automated online measurement of antibody titers in antibody production. The device incorporates a fully automated affinity-column based instrument. | 2021-02-04 |
20210033625 | DEFECTIVE CALCIUM SIGNALING AS A TOOL IN AUTISM SPECTRUM DISORDERS - The present invention features methods of detecting the level of inositol trisphosphate receptor (IP | 2021-02-04 |
20210033626 | A SCREENING METHOD FOR CEREBROTENDINOUS XANTHOMATOSIS USING BILE ALCOHOL GLUCURONIDES AND METABOLITE RATIOS - The invention relates to a method of diagnosing or screening for 27-hydroxylase (CYP27A1) deficiency in an animal comprising: determining in a biological sample the intensity signal by mass analysis of at least a bile alcohol glucuronide and a C24- or C27-bile acid or a conjugate thereof, comparing the intensity signals to a control sample or control value, and determining 27-hydroxylase (CYP27A1) deficiency based on said comparison. | 2021-02-04 |
20210033627 | Diagnosis of Liver Pathology Through Assessment of Protein Glycosylation - Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting lectin binding on proteins in biological fluids, and comparing the detected lectin binding with reference values for the binding of lectin of such proteins in healthy or disease states. | 2021-02-04 |
20210033628 | DIAGNOSTIC AND DRUG SCREENING FOR MOLECULAR SIGNATURES OF EARLY ONSET SPORADIC PARKINSON'S DISEASE - Induced Pluripotent Stem Cell (Ipsc) technology enables the generation and study of living brain tissue relevant to Parkinson's disease (PD) ex vivo. Utilizing cell lines from PD patients presents a powerful discovery system that links cellular phenotypes observed in vitro with real clinical data. Differentiating patient-derived iPSCs towards a dopaminergic (DA) neural fate revealed that these cells exhibit molecular and functional properties of DA neurons in vitro that are observed to significantly degenerate in the substantia nigra of PD patients. Clinical symptoms that drive the generation of other relevant cell types may also yield novel PD-specific phenotypes in vitro that have the potential to lead to new therapeutic avenues for patients with PD. Due to their early onset and non-familial origin, differentiated nervous tissue from these patients offer a key opportunity to discover neuron subtype-specific pathological mechanisms and importantly interrogate the contribution of their genetic background in susceptibility to PD. | 2021-02-04 |
20210033629 | INTERFACE MODULE FOR ROBOTIC LOADING AND UNLOADING OF A SAMPLE MANAGER FOR LIQUID CHROMATOGRAPHY - Described is an interface module for robotic loading and unloading of a liquid chromatography sample manager. The module includes a transfer drawer receiving apparatus having a device track and a drawer drive system configured to transport a transfer drawer along the device track into and out from a sample tray of a sample manager. The transfer drawer receives a sample-vial carrier that holds samples to be analyzed. The module further includes a window apparatus that has a window controllable to be in an open state or a closed state. When in the open state, transport of the transfer drawer through the window into or out from the sample manager permits loading of the sample-vial carrier into the sample tray and unloading of the sample-vial carrier from the sample tray. In the closed state, the window apparatus substantially seals the internal environment of the sample manager from the ambient environment. | 2021-02-04 |
20210033630 | METHOD FOR TESTING, VERIFYING, CALIBRATING OR ADJUSTING AN AUTOMATIC ANALYSIS APPARATUS - A method is disclosed for determining a parameter dependent on the concentration of a substance in a sample liquid. The method includes determining a first measured value representing a value of the parameter in a first standard solution using the automatic analysis apparatus, wherein the value of the parameter in the first standard solution is known, and determining a second measured value representing a value of the parameter in a second standard solution using the automatic analysis apparatus, wherein the value of the parameter in the second standard solution is known and differs from the value of the parameter in the first standard solution. The first standard solution or the second standard solution is automatically produced using the analysis apparatus by mixing a predetermined volume of a stock solution containing the substance and a predetermined volume of a dilution liquid. | 2021-02-04 |
20210033631 | AUTOMATED SYSTEM FOR SAFE SAMPLE COLLECTION, TRANSFER, AND ANALYSIS - Systems and methods for safe collection and transportation of fluid samples for analysis are described to avoid exposure of hazardous materials to personnel during collection and transfer of samples to laboratory processing equipment. A system embodiment includes, but is not limited to, a sample module including an enclosure configured to separate a sample from an external environment; a filling station defining a compartment into which the sample module can be received, the filling station configured to direct a fluid sample into the sample module and to rinse fluid connections between the filling station and the sample module prior to decoupling of the sample module from the filling station; and a sample transfer station configured to receive the sample module and to transfer sample from the sample module and direct the sample into a sample container. | 2021-02-04 |
20210033632 | LINK CHAIN, CHAIN SYSTEM AND METHOD - Described is a chain including a plurality of links pivotally connected to each other such that the chain is configured to bend in one direction without back-bending. Each of the plurality of links including a link body include: an inner side facing a bending direction of the chain; an outer side facing opposite the bending direction of the chain; a back-bending prevention portion; a post feature extending laterally across the link body, and a connection feature configured to engage with the post feature of the first other of the pivotally connected plurality of links to create one direction pivotal attachment without back-bending between the links. Further disclosed is a chain system and methods of moving devices with a chain or chain system. | 2021-02-04 |
20210033633 | METHOD OF LOADING SAMPLES INTO A SAMPLE MANAGER OF A CHROMATOGRAPHY SYSTEM - Described is a method for loading a sample-vial carrier into a sample manager of a liquid chromatography system. The method includes placing a sample-vial carrier onto a transfer drawer having first and second drawer magnets. The transfer drawer is transported into a sample tray of a sample manager using a drawer drive system of a transfer drawer receiving apparatus. The drawer drive system has a drive magnet that is engaged with the first drawer magnet during transport. The transport of the transfer drawer is terminated when the second drawer magnet is engaged with a sample tray magnet on the sample tray. The sample tray is rotated about an axis substantially perpendicular to a direction of transport of the transfer drawer to provide a shear force to disengage the first drawer magnet from the drive magnet. | 2021-02-04 |
20210033634 | AUTOMATED VOLUMETRIC DEVICE - The present invention concerns the technical field of volumetric measurement and volumetric instruments and provides novel devices and methods for the determination of the volume of a fluid. | 2021-02-04 |
20210033635 | SAMPLING MECHANISM AND SAMPLING METHOD - Provided is a sampling mechanism capable of performing sampling through proper perforation with respect to a plug body. A perforating body has a first piercer inserted into a cap and penetrating the cap with a tip closed and a second piercer formed in a tubular shape, disposed outside the first piercer, approaching the cap together with the first piercer by causing the first piercer to protrude downward, reaching the cap after the first piercer reaches the cap, and penetrating the cap by being inserted into the cap. A probe is passed through the second piercer remaining after retraction of the first piercer. | 2021-02-04 |
20210033636 | METHOD AND APPARATUS FOR IMPLEMENTING DRIVE SIGNAL FOR DRIVING RESOLVER SENSOR - A method and apparatus for generating a drive signal for driving a resolver sensor are provided. The method and apparatus implement a drive signal to be input to a resolver sensor. The method and apparatus perform counting in association with an incoming square wave signal and implement a drive signal after confirming that a specific point corresponding to a preset condition of the incoming square wave signal arrives. | 2021-02-04 |
20210033637 | Situational Awareness Trainer - This disclosure relates to methods and devices for detecting configurations of aircraft. A sound is recorded from an interior of an aircraft. A transform is calculated of the sound. The transform is compared with a calibration transform of a known configuration. A closeness parameter is determined based on the comparison. A detected configuration is indicated if the closeness parameter is above a threshold. | 2021-02-04 |
20210033638 | MOTION SENSING MODULE - A motion sensing module including a plurality of first and second magneto-resistive sensors and a processor is provided. The processor executes the following steps S | 2021-02-04 |
20210033639 | INERTIAL SENSOR, ELECTRONIC APPARATUS, AND VEHICLE - An inertial sensor includes: a substrate; a moving element swinging about a swing axis along a Y-axis; a detection electrode provided at the substrate, overlapping the moving element as viewed in a plan view from a Z-axis direction orthogonal to the Y-axis, and forming an electrostatic capacitance with the moving element; an exposure part provided at an inner side of the detection electrode and exposing a surface facing the moving element, of the substrate; a protrusion overlapping the moving element as viewed in a plan view from the Z-axis direction and protruding toward the moving element from the exposure part of the substrate; and a covered electrode provided at a top of the protrusion and having a same electric potential as the moving element. | 2021-02-04 |
20210033640 | APPARATUS AND METHODS FOR QUANTUM BEAM TRACKING - A method includes sending a probe beam into a beam path that induces a lateral displacement to the probe beam. The probe beam includes a plurality of orthogonal spatial modes that are entangled with each other. The method also includes measuring a phase of each spatial mode from the plurality of orthogonal spatial modes in the probe beam at a detector disposed within a near field propagation regime of the probe beam. The method also includes estimating the lateral displacement of the probe beam based on a phase of each spatial mode from the plurality of spatial modes in the probe beam after the beam path. | 2021-02-04 |
20210033641 | POWER INTERFACE - The present disclosure relates to a power interface, and more particularly, to a power interface for electrically connecting an object to be tested and a test driving unit. The electric power interface in accordance with an exemplary embodiment includes: a support member; an elastic member fixed to the support member and configured to provide an elastic force in a vertical direction; a first connection terminal disposed on the elastic member; a second connection terminal electrically connected to the first connection terminal; and a flexible sheet has one side fixed to the elastic member and the other side fixed to the support member to restrict a deformation range of the elastic member. | 2021-02-04 |
20210033642 | Probe Module and Probe - As a semiconductor device is miniaturized, a scribe area on a wafer also tends to decrease. Accordingly, it is necessary to reduce the size of a TEG arranged in the scribe area, and efficiently arrange an electrode pad for probe contact. Therefore, it is necessary to associate probes and the efficient layout of the electrode pad. The purpose of the present invention is to provide a technique for associating probes and the layout of an electrode pad of a TEG to facilitate the evaluation of electrical characteristics. According to the present invention, the above described problem can be solved by arranging a plurality of probes in a fan shape or manufacturing the probes with micro electro mechanical systems (MEMS) technology. | 2021-02-04 |
20210033643 | ELECTRO-OPTICAL CIRCUIT BOARD FOR CONTACTING PHOTONIC INTEGRATED CIRCUITS - An electro-optical circuit board can provide probe card functionality. The electro-optical circuit board includes at least one electrical conductor track and at least one optical beam path. | 2021-02-04 |
20210033644 | LOW-GLITCH RANGE CHANGE TECHNIQUES - Techniques are provided for changing a range of an output circuit with little or no voltage or current glitch. In an example, a method of changing a range of an output signal can include providing a first level of the output signal at an output of a first amplifier based on a received setpoint signal and receiving a range change command. In response to the range change command an input of a second amplifier can be shorted to an output of the second amplifier for a first interval. At the end of the first interval and over a second interval, a first impedance between the input of the second amplifier and the output of the second amplifier can be increased, and a second impedance between the input of the second amplifier and the setpoint signal can be increased. | 2021-02-04 |
20210033645 | DEVICE FOR DETECTING CURRENT LEAKAGE AND CURRENT LEAKAGE DETECTION SYSTEM INCLUDING THE SAME - A device for detecting a current leakage and a current leakage detection system including the same are provided. The device for detecting a current leakage includes a magnetic core having an internal space and both ends the core are separated from each other. An electric wiring extends to pass through the internal space of the magnetic core, and is connected between a power source and an electric load to supply power from the power source to the electric load. A hall sensor senses a magnetic field induced in the magnetic core. | 2021-02-04 |
20210033646 | Multi-Die Integrated Current Sensor - A current sensor can include a lead frame. The lead frame can include a first lead and a second lead, wherein the first and second leads are coupled together at a first junction region of the lead frame, wherein the current sensor is operable to sense a magnetic field generated by a first current passing through the first junction region. The current sensor can further include a first die disposed proximate to the lead frame. The first die can include a first magnetic field sensing element disposed on a surface of the first die, a first circuit coupled to the first magnetic field sensing element for generating a first signal indicative of a first current, and a first node coupled to the first signal. The current sensor can further include a second die disposed proximate to the lead frame. The second die can include a second magnetic field sensing element disposed on a surface of the second die, a second circuit coupled to the second magnetic field sensing element for generating a second signal indicative of the first current passing through the first junction region or indicative of a second current passing through the lead frame and a second node coupled to the second signal. | 2021-02-04 |
20210033647 | SENSOR WHICH SENSES THE INSTANTANEOUS RATE OF CHANGE OF A CURRENT, SAID SPEED SENSOR BEING GALVANICALLY ISOLATED AND INTEGRATED ON A PRINTED CIRCUIT BOARD - A sensor is configured to sense the rate of change of a current in order to protect the bridge arms in a power module with power layers and measurement layers. The sensor includes at least three conductors (C | 2021-02-04 |
20210033648 | CURRENT SENSOR - Embodiments of the invention are directed to a current sensor that includes a current controlled oscillator circuit configured to receive an input current and to provide an output signal having an output frequency which is dependent on the input current. The current sensor further includes a feedforward circuit configured to adapt a reference voltage of the current controlled oscillator in dependence on an instantaneous current value of the input current. | 2021-02-04 |
20210033649 | CURRENT DETECTION APPARATUS - A current detection apparatus includes a voltage detector, a candidate voltage generator, a temperature detector and a correction voltage selector. The voltage detector includes an output terminal for outputting a detected voltage according to a load current. The candidate voltage generator includes correction resistors connected in series and connecting the output terminal and a ground. The candidate voltage generator generates candidate voltages at respective sections across the corresponding correction resistors. The temperature detector detects a temperature of a semiconductor switch. The correction voltage selector selects one of the candidate voltages as a corrected voltage. The one of the candidate voltages is weighted with corresponding one of the corrected magnification scales corresponding to an on-resistance of the semiconductor switch at the measured temperature. The corrected voltage indicates a corrected current value with correction of the load current according to the measured temperature. | 2021-02-04 |
20210033650 | METHOD AND DEVICE FOR POSITIONING EQUIPMENT-LEVEL OSCILLATION SOURCES OF DFIG GRID-CONNECTED SYSTEM - The application relates to a method and device for positioning equipment-level oscillation sources of DFIG grid-connected system, which belongs to the technical field of wind generation, and solves the problem of stable operation of the wind power grid-connected system at the current stage. The method comprises: constructing the energy correlation topology network of the components in DFIG; analyzing the dynamic energy flows between the components during the oscillation process; calculating magnitudes of the causality between the dynamic energy flows; building a causality diagram of oscillation transmission in the DFIG; analyzing the distribution of the magnitude of the causality in the diagram, determining the oscillation transmission routes and locating the oscillation sources. | 2021-02-04 |
20210033651 | METHOD AND APPARATUS FOR MONITORING POWER TRANSMISSION - An apparatus for measurement of power in an electric power transmission line is disclosed. The apparatus comprises a magnetic field sensor for measuring the magnetic field at the electric power transmission line and transmitting magnetic field data to a processor. The magnetic field sensor is arranged at a minimum threshold distance from the electric power transmission line. The apparatus also has a voltage sensor arranged distally from the magnetic field sensor for transmitting voltage waveform data to the processor and a transfer function calculator for calculating the relationship between the transmitted voltage waveform data at the voltage sensor and transmission line voltage waveform data. | 2021-02-04 |
20210033652 | SENSOR, SENSOR SIGNAL PROCESSOR, AND POWER LINE SIGNAL ENCODER - Provided is a sensor in which a current sensor that detects a current of a power line as a change in a magnetic field and a voltage sensor that detects a voltage of the power line using capacitive coupling are integrally formed. The transmission of signals related to substantially the same sections is omitted in order to effectively compress an output signal from the sensor and an output signal from the voltage sensor. When the amplitude and phase of a fundamental wave which are estimated from the output signal from the sensor and the amplitude and phase of harmonics are encoded, the amplitude and phase of the harmonics are relativized with a value for the fundamental wave. | 2021-02-04 |
20210033653 | METHOD AND DEVICE FOR DETECTING POSITIONAL CHANGE AMOUNT DUE TO MOVEMENT OF MOVING BODY - The present invention provides a method for detecting a positional change amount due to a movement of a moving body by reading, with a sensor, a plurality of gradations disposed along the direction of the movement. The method includes: a step for taking, as one period, one gradation among the plurality of gradations and acquiring a pseudo sinusoidal signal in response to the positional change amount; a step for executing a Fourier transform on the pseudo sinusoidal signal within the range of at least one gradation, and calculating, from the spectral intensity of each frequency component obtained by the Fourier transform, the signal intensity of a fundamental wave component and the signal intensity of at least one harmonic component; a step for calculating a gain corresponding to each of the at least one harmonic component by dividing each signal intensity of the at least one harmonic component by the signal intensity of the fundamental wave component; and a step for detecting the positional change amount by subtracting, from the pseudo sinusoidal signal, each harmonic component multiplied by a corresponding gain. | 2021-02-04 |
20210033654 | DETECTOR AND METHOD FOR MEASURING A RESISTANCE OF A VARIABLE RESISTANCE SENSOR WHOSE RESISTANCE VARIES WITH RESPECT TO A TIME-VARYING STIMULUS - A detector for measuring a resistance of a variable resistance sensor (VRS) that varies with respect to a time-varying stimulus (e.g., temperature) includes a voltage reference having variation with respect to operating conditions and a linearized digital-to-analog converter (LIDAC) having a known transconductance that uses the voltage reference to generate a current for pumping into the VRS to cause the VRS to generate a voltage sensed by the detector. The sensed voltage includes error due to the variation of the voltage reference. The detector also includes a programmable gain amplifier (PGA) that gains up the sensed voltage to generate an output signal, an ADC that converts the output signal to a digital value, and a digital processor that computes the resistance of the VRS using the digital value and the known transconductance. The PGA is non-varying with respect to the time-varying stimulus. | 2021-02-04 |
20210033655 | CAPACITANCE DETECTION METHOD AND CIRCUIT - A capacitance detection method and circuit are provided. The detection method includes: performing charging, base capacitance offsetting, and charge transferring successively on a capacitor to be detected in an i-th first offsetting process of the first offsetting processes, to generate a first output voltage, wherein i≤N; performing discharging, base capacitance offsetting, and charge transferring on the capacitor to be detected successively in a j-th second offsetting process of the second offsetting processes, to generate a second output voltage, wherein j≤M; and determining a capacitance variation of the capacitor to be detected before and after the capacitor to be detected is affected by an external electric field based on the first output voltages corresponding to N first offsetting processes and the second output voltages corresponding to M second offsetting processes in the detection period. | 2021-02-04 |
20210033656 | SENSOR FOR MEASUREMENT OF ELECTROSTATIC POTENTIAL WITHOUT CURRENT LOADING AND WITHOUT MECHANICAL CHOPPING - An electric field detecting system is provided that comprises a first metal plate, a second metal plate, a sensor and a detector. The sensor has a first metal layer, a second metal layer and a non-linear permittivity dielectric material disposed between the first metal layer and the second metal layer. The first metal layer is electrically connected to the first metal plate, whereas the second metal layer is electrically connected to the second metal plate. The detector can detect a voltage between the first metal layer and the second metal layer and can determine a magnitude of the electric field based on the detected voltage and a priori information related to a variable capacitance of the non-linear permittivity dielectric material. | 2021-02-04 |
20210033657 | METHOD FOR CHECKING A CAPACITY OF A SUPPLY LINE - A method for checking a capacity of at least one supply line for an electrically operated assembly that is coupled electrically via the at least one supply line to an electrical system of an at least partially automated mobile platform. The method includes: ensuring a non-critical operating state of the mobile platform; determining an off-load terminal voltage at an input connection of the assembly, with zero-current supply line; applying a defined current to the supply line of the electrically operated assembly; determining an on-load terminal voltage at the input connection of the assembly, in doing so, the defined voltage being applied to the supply line of the electrically operated assembly; determining a differential voltage between the off-load terminal voltage and the on-load terminal voltage; comparing the differential voltage to a differential-voltage limit value to determine whether the capacity of the electric supply line is sufficient to operate the assembly. | 2021-02-04 |
20210033658 | Magnetic Photoacoustic Composite non Destructive Testing Device of Power Transmission Line of Photovoltaic Grid based on Corona Effect - Disclosed is a magnetic photoacoustic composite non destructive testing device for a power transmission line of a photovoltaic grid based on a corona effect. The device may include a mechanical structure part and a data processing part. The mechanical structure part may include a shielding shell and mounting bases, shielding bodies are mounted on two sides of the shielding shell, a top of the shielding shell is provided with an upper cover, two sides under the upper cover are provided with the mounting base respectively, and the two mounting bases are located above the shielding bodies respectively. The data processing part may include a pair of optical sensing modules, a pair of magnetic sensing modules, an acoustic sensing module, a humidity sensing module, a micro-processor, a signal conditioning and transmission unit and an internal power supply management module. | 2021-02-04 |
20210033659 | Electronic Test Equipment Apparatus and Methods of Operating Thereof - An electronic test equipment apparatus includes a power terminal configured to receive power, an interface for a device under test (DUT), at least one power transistor connected in series between the power terminal and the interface for the DUT, and a protection circuit. The protection circuit is configured to: switch on the at least one power transistor, to electrically connect the power terminal to the DUT through the interface as part of a test routine; and subsequently automatically switch off the at least one power transistor after a predetermined delay, to electrically disconnect the power terminal from the DUT regardless of whether the DUT passes or fails the test routine. A voltage clamp circuit for electronic test equipment and corresponding methods of testing devices using such electronic test equipment are also described. | 2021-02-04 |
20210033660 | ENABLING OF FUNCTIONAL LOGIC IN IC USING THERMAL SEQUENCE ENABLING TEST - An integrated circuit (IC) includes functional logic therein that can be enabled by application of a predefined thermal cycle. The IC includes an enabling fuse operatively coupled to the functional logic, the functional logic being disabled unless enabled by activation of the enabling fuse. A set of thermal sensors are arranged in a physically distributed manner through at least a portion of the IC. A test control macro operatively couples to the set of thermal sensors and the enabling fuse for activating the enabling fuse to enable the functional logic in response to application of a thermal cycle that causes the set of thermal sensors to sequentially experience a thermal condition matching a thermal sequence enabling test. A related method and system for applying the predefined thermal cycle are also provided. | 2021-02-04 |
20210033661 | AUTOMATIC CIRCUIT BOARD TEST SYSTEM AND AUTOMATIC CIRCUIT BOARD TEST METHOD APPLIED THEREIN - An automatic circuit board test system includes at least one switch module of board under test connected with a test board, a control module and a test process module. The test board includes a first signal interface, a second signal interface and a third signal interface and a repeater. The second signal interface and the third signal interface are mutually connected by a signal cable. The first signal interface is connected with the repeater. The at least one switch module of board under test is connected with the second signal interface and the third signal interface. The control module is connected with the at least one switch module of board under test. The control module controls the at least one switch module of board under test. The test process module is connected with the control module and the first signal interface by at least two serial port buses. | 2021-02-04 |
20210033662 | Calibration of Digital Isolators - A method for calibrating an isolator product includes generating a differential pair of signals on a differential pair of nodes at an input of a demodulator circuit of a receiver signal path of a first integrated circuit die of the isolator product based on a received differential pair of signals. The method includes generating a diagnostic output signal having a level corresponding to an average amplitude of the differential pair of signals. The method includes driving the diagnostic output signal to an output terminal of the isolator product. The method may include transmitting a diagnostic signal using a carrier signal having a frequency by a second integrated circuit die via an isolation channel. The method may include, during the transmitting, sweeping the frequency of the carrier signal across a frequency band. The method may include, during the sweeping, capturing the diagnostic output signal via the output terminal. | 2021-02-04 |
20210033663 | INTEGRATED CIRCUIT TESTING SYSTEM AND METHOD - A method of testing an integrated circuit includes connecting a conductive line to a ground voltage. The method further includes directly physically contacting the conductive line with a first conductive structure. The method further includes contacting the conductive line with a second conductive structure different from the first conductive structure. The method further includes supplying a first test voltage to the conductive line through the first conductive structure. The method further includes supplying a second test voltage to the conductive line through the second conductive structure. The method further includes generating a report indicating whether the first conductive structure is capable of carrying the first test voltage based on feedback from a first test circuit connected to the first conductive structure. | 2021-02-04 |
20210033664 | SIGNAL TRANSMISSION SYSTEM - A signal transmission system with at least one signal encoder, a line, and a control and evaluation unit, wherein the signal encoder has an electronic unit and a power source, wherein the signal encoder feeds an imprinted current in the range between a preset first value and a preset second value into the line, in particular between 4 and 20 mA. The control and evaluation unit has a load and a microprocessor, and captures and evaluates a voltage that decreases via the load or a current that flows through the load. Additional information regarding the status of the components, can thus be captured and forwarded in a simple way, in that the load in the control and evaluation unit is connected in series to at least one electrical component at which a direct current appears when a current flows through the electrical component. | 2021-02-04 |
20210033665 | MEMORY CONTROLLER WITH INTEGRATED TEST CIRCUITRY - A memory controller instantiated on a semiconductor IC device comprises a timing circuit to transfer a timing signal, the timing circuit being configured to receive a first test signal and to effect a delay in the timing signal in response to the first test signal, the first test signal including a first timing event. The memory controller further comprises an interface circuit configured to transfer the data signal in response to the timing signal, the interface circuit being further configured to receive a second test signal and to effect a delay in the data signal in response to the second test signal, the second test signal including a second timing event that is related to the first timing event according to a test criterion. | 2021-02-04 |
20210033666 | PROBER - A prober includes: a stage that places a substrate formed with a plurality of chips thereon in a matrix; a contact that sequentially contacts with electrode pads of the plurality of chips thereby performing an inspection on electrical characteristic of the plurality of chips; a plurality of LED units provided on a side opposite to a placing surface of the stage so as to independently heat a plurality of areas where the plurality of chips are located, respectively, and each including one or a plurality of LEDs; and a controller that outputs a control signal to drive, among the plurality of LED units, at least an LED unit corresponding to an area of a chip to be inspected, among the area of the chip to be inspected and peripheral areas of the corresponding area. | 2021-02-04 |
20210033667 | Contactor And Handler - A contactor includes a temperature adjustment mechanism, a cover and a path. The temperature adjustment mechanism increases and decreases temperature of an electronic component via a contact portion. The cover externally covers the temperature adjustment mechanism and includes an aperture portion. The path is allowed to supply gas to inside of the cover. The cover is configured to change a distance from the aperture portion to the contact portion. | 2021-02-04 |
20210033668 | ANTENNA-IN-PACKAGE PRODUCTION TEST - A test assembly for testing an antenna-in-package (AiP) device includes a socket over a circuit board, where the socket includes an opening for receiving the AiP device; a plunger configured to move along sidewalls of the opening, where during testing of the AiP device, the plunger is configured to cause the AiP device to be pressed towards the circuit board such that the AiP device is operatively coupled to the circuit board via input/output connections of the AiP device and of the circuit board; and a loadboard disposed within the socket and between the plunger and the AiP device, where the loadboard includes a coupling structure configured to be electromagnetically coupled to a transmit antenna and to a receive antenna of the AiP device, so that testing signals transmitted by the transmit antenna are conveyed to the receive antenna externally relative to the AiP device through the coupling structure. | 2021-02-04 |
20210033669 | Reversible Multi-Bit Scan Cell-based Scan Chains For Improving Chain Diagnostic Resolution - A circuit comprises a scan chain comprising one or more multi-bit flip-flops, a plurality of multiplexers, and new scan enable signal generation circuitry. Each of the plurality of multiplexers is associated with a particular bit of the one or more multi-bit flip-flops with an output of the each of the plurality of multiplexers coupled to a data input of the particular bit, which is configured to select, based on a scan direction control signal, between an input signal from functional circuitry of the circuit and an input signal from a data output of a bit of the scan chain immediately following the particular bit in a normal scan shift direction. The new scan enable signal generation circuitry is configured to generate a new scan enable signal for the one or more multi-bit flip-flops based on the scan direction control signal and a scan enable signal for the scan chain. | 2021-02-04 |
20210033670 | Method and Apparatus for Analyzing Phase Noise in a Signal From an Electronic Device - An apparatus and method for analyzing phase noise in a signal. A plurality of signal samples, each signal sample representing a value of phase noise in a signal-under-test at a corresponding offset frequency, and filter data representing filter characteristics on a first side of a spectrum boundary, are used to derive filtered signal samples. A measure of noise is derived from the filtered signal samples. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract. | 2021-02-04 |
20210033671 | TEST ACCESS PORT WITH ADDRESS AND COMMAND CAPABILITY - The disclosure provides a novel method and apparatus for inputting addresses to devices to select the device TAP for access. Further, the disclosure provides a novel method and apparatus for inputting addresses for selecting device TAPs and for inputting commands for commanding circuitry within the device. The inputting of addresses or the inputting of addresses and commands is initiated by a control bit input on TDI that is recognized during the Run Test/Idle, Pause-DR or Pause-IR TAP states. | 2021-02-04 |
20210033672 | METHOD AND DEVICE FOR TESTING AT A SPECIFIC CHANNEL CONDITION - A method for testing a device under test at a specific channel condition is provided. The method comprises the steps of initiating a communication with the device under test and receiving a transmission frame from the device under test with a header portion comprising a specific transmission rate information. It also comprises analyzing the header portion of the transmission frame in order to determine whether the device under test is transmitting with the specific transmission rate information. | 2021-02-04 |
20210033673 | PROGRAMMABLE INTEGRATED CIRCUIT WITH INTERNAL DIAGNOSTIC HARDWARE - A programmable integrated circuit may include logic, signal select hardware, programmable signal analysis hardware, an embedded microcontroller, and a hardware interface. The logic performs one or more functions and outputs a plurality of signals. The signal select hardware selects one or more of the signals output from the logic. The programmable signal analysis hardware analyzes the selected signals to produce diagnostic data. The embedded microcontroller receives the diagnostic data from the programmable signal analysis hardware and may reconfigure the logic based on the diagnostic data. The hardware interface connects the programmable signal analysis hardware and the embedded microcontroller to transport the diagnostic data. | 2021-02-04 |