08th week of 2009 patent applcation highlights part 42 |
Patent application number | Title | Published |
20090048410 | Membrane Active Heteropolymers - The present invention is directed to a class of membrane active polymers useful for cellular delivery of compounds. Conjugation of the described membrane active polymers to targeting, anti-opsonization, and anti-aggregation agents provides polymers suitable for in vivo delivery. The use of multiple reversible linkages connecting component parts provides for physiologically responsive activity modulation. | 2009-02-19 |
20090048411 | Processes for producing ethylene and carbon monoxide mixtures from ethane - A method for producing a mixture of ethylene and carbon monoxide by contacting ethane and an oxygen source at a temperature of at least 500° C. to produce ethylene and carbon monoxide. A method for producing an alkyl propionate by steps of: (a) contacting ethane and an oxygen source at a temperature of at least 500° C. to produce ethylene; (b) contacting an alcohol, ethylene and carbon monoxide with an ethylene carbonylation catalyst to produce the alkyl propionate; and (c) separating the alkyl propionate from byproducts and starting materials. The method further comprises condensing the alkyl propionate with formaldehyde to produce an alkyl methacrylate. | 2009-02-19 |
20090048412 | Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs - The invention relates to an amphiphilic-BMP polymer complex which is physically and chemically stable and soluble in water, characterised in that:
| 2009-02-19 |
20090048413 | Method for Production of Conjugated Polymer - A method for production of a conjugated polymer comprising contacting (A) an aromatic monomer having at least two boron-containing functional groups with an aromatic monomer having at least two reactive functional groups or (B) aromatic monomers having at least one boron-containing functional group and at least one reactive functional group with each other, both in an ether solvent in the presence of a palladium catalyst wherein a phosphine compound is coordinated to palladium, cesium carbonate and 1 to 100 moles of water per 1 mole of the boron-containing functional group of the above-mentioned aromatic monomer. | 2009-02-19 |
20090048414 | MAGNETIC COUPLING THROUGH STRONG HYDROGEN BONDS - A composition of matter for a polymeric material for magnetic coupling through strong hydrogen bonds. A hydrogen bound structural directing entity, such as the bifluoride ion, HF | 2009-02-19 |
20090048415 | METAL COMPLEXES - The present invention describes novel metal complexes. Compounds of this type can be employed as functional materials in a number of different applications which can be ascribed to the electronics industry in the broadest sense, in particular as red-emitting compounds. | 2009-02-19 |
20090048416 | PRODUCTION AND USE OF HIGHLY FUNCTIONAL, HIGHLY BRANCHED OR HYPERBRANCHED POLYLYSINES - The present invention relates to new high-functionality, highly branched or hyperbranched polylysines, to processes for preparing them, and to their use. | 2009-02-19 |
20090048417 | Biodegradable Shower Mat - A biodegradable shower mat has been disclosed. | 2009-02-19 |
20090048418 | Organic polyurethane shape memory material and a preparation method thereof - An organic polyurethane shape memory material and a preparation method thereof are disclosed. The organic polyurethane shape memory material includes a C10 chain or C18 chain and it consists of hard segment and soft segment. The preparation method thereof includes the steps of: | 2009-02-19 |
20090048419 | POLYURETHANE ELASTOMER - A polyurethane elastomer obtained by reacting at the least a di, tri or polyisocyanate, a polycarbonate diol and a di, tri or polyalcohol characterized in, that said polycarbonate diol is at least one polycarbonate diol of a 2-alkyl-1,3-propanediol, a 2,2-dialkyl-1,3-propanediol, an alkoxylated 2-alkyl-1,3-propanediol and/or an aldoxylated 2,2-dialkyl-1,3-propanediol and/or is at least one polycarbonate diol comprising units from two or more said 1,3-propanediols, wherein alkyl is a linear or branched aliphatic alkanyl having 1-8 carbon atoms and alkoxylated is ethoxylated, propoxylated and/or butoxylated having 1-20 alkoxy units. | 2009-02-19 |
20090048420 | Process for the preparation of polyols - The present invention provides polyols which can be obtained by a simple process. These polyols, unless explicitly specified, are to be understood to encompass both polyether polyols and polyether ester polyols. The invention further provides the simple process for the production of the polyols, and also, the production of polyurethanes comprising reacting a polyol according to the invention with a polyisocyanate. | 2009-02-19 |
20090048421 | FILM FORMING COMPOSITION, FILM, AND ELECTRONIC DEVICE - A film forming composition is provided that includes a compound represented by Formula (1) below and/or a polymer polymerized using at least a compound represented by Formula (1) below | 2009-02-19 |
20090048422 | RESIN COMPOSITION FOR COMPOSITE MATERIAL PARTS - A resin composition for composite material parts includes a main agent composed of an epoxy resin and a reactive diluent, and a curing agent. The reactive diluent, which is monomer or oligomer of acrylate or methacrylate having one or more vinyl (unsaturated double bond) functional groups and has low viscosity at room temperature, is used in an amount of 5 to 30 parts by weight based on 100 parts by weight of the main agent such that the main agent has a viscosity of 700 to 3000 cps at 25° C. The resin composition of the present invention is very suitable for being used to manufacture composite material parts used in wind blade, boat, automobile and aircraft by the manufacturing process such as vacuum infusion and hand lay-up vacuum assisted resin infusion process. | 2009-02-19 |
20090048423 | Phospholipid Copolymers - The present disclosure provides copolymers including a first monomer including at least one phospholipid possessing at least one hydroxyl group and a second monomer including a cyclic monomer. Compositions, medical devices, and coatings including such copolymers are also provided. | 2009-02-19 |
20090048424 | FLUOROSULFONYL GROUP-CONTAINING MONOMER AND ITS POLYMER, AND SULFONIC ACID GROUP-CONTAINING POLYMER - To provide a fluorosulfonyl group-containing monomer having a high polymerization reactivity and plural fluorosulfonyl groups. Further, to provide a fluorosulfonyl group-containing polymer and a sulfonic acid group-containing polymer, obtained by using the monomer. | 2009-02-19 |
20090048425 | PROCESS FOR PRODUCTION OF CYCLOOLEFIN - According to the present invention, when cycloolefins are produced by partially hydrogenating a monocyclic aromatic hydrocarbon with hydrogen in the presence of a ruthenium catalyst, water, and a metal sulfate, the decrease in catalytic activity and cycloolefin selectivity is suppressed by reducing the concentration of chloride ions dissolved in the water in which the catalyst is present to 300 wt ppm or less and regenerating a part or all of the catalyst for reuse. Zinc sulfate is preferably used as the metal sulfate. Further, the raw materials and catalyst to be supplied to the reaction preferably have a reduced chloride ion content. This method can suppress the decrease in long-term catalytic activity and cycloolefin selectivity. Furthermore, the catalytic activity and cycloolefin selectivity after catalyst regeneration can be maintained at a high level. As a result, cycloolefins can be efficiently produced for a long period of time. | 2009-02-19 |
20090048426 | POLYMERIZABLE PHOSPHONIC ACID DERIVATIVE AND ADHESIVE COMPOSITION COMPRISING THE SAME - The present invention provides an adhesive composition comprising a polymerizable phosphonic acid derivative which is a composition having intramolecularly a polymerizable group and a phosphonic acid group, represented by the general formula [1]: | 2009-02-19 |
20090048427 | HYBRIDIZATION AND MISMATCH DISCRIMINATION USING OLIGONUCLEOTIDES CONJUGATED TO MINOR GROOVE BINDERS - Conjugates between a minor groove binding molecule, such as the trimer of 1,2-dihydro-(3H)-pyrrolo[3,2-e]indole-7-carboxylate (CDPI | 2009-02-19 |
20090048428 | PEPTIDE TAGS FOR THE EXPRESSION AND PURIFICATION OF BIOACTIVE PEPTIDES - Peptide tags, referred to here as inclusion body tags, are disclosed and are useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag. | 2009-02-19 |
20090048429 | Processes and intermediates - The invention relates to processes and compounds useful for producing modified aspartic acid derivatives, such as aspartic acid aldehyde moieties. Aspartic acid derivatives are useful for preparing caspase inhibitors and/or prodrugs thereof. | 2009-02-19 |
20090048430 | Site specific protein modification - The present invention relates, in general, to protein modifications and, in particular, to a method of effecting site-specific labeling of proteins with covalently coupled reporter groups. The invention further relates to a method of effecting orientation-specific immobilization of proteins on a solid surface. The invention also relates to products produced by such methods. | 2009-02-19 |
20090048431 | MULTIVALENT CLOSTRIDIAL TOXINS - The present invention is directed to multivalent Clostridial toxin comprising more than one binding domain directed to a cell surface molecule of a target cell. Such modified toxins are useful as therapeutic compositions to prevent exocytosis and secretion by the target cell. Conditions in which such compositions man be useful include, without limitation, disorders of the sensory or motor nervous system, acute or chronic pain, cancer, pancreatitis, hyperhydrosis, glandular disorders, viral infections, cystic fibrosis and the like. The invention is also directed to methods of using and administering such a composition, and methods of treating a given condition using such a composition. | 2009-02-19 |
20090048432 | ANTI-IL-20 ANTIBODY AND ITS USE IN TREATING IL-20 ASSOCIATED INFLAMMATORY DISEASES - This invention features an antibody specifically binding to human IL-20 (e.g., mAb 7E and a equivalent thereof) and its use in treating an IL-20 associated inflammatory disease, such as atherosclerosis, RA, psoriasis, psoriatic arthritis, bacteria-induced gastric ulcer, and acute renal failure. | 2009-02-19 |
20090048433 | Scalable Process for Protein Purification - The invention provides a process for the purification recombinantly expressed, self-assembled VLP from the homogenate of a bacterial host, wherein the process can be scaled up to a commercial production scale in a cost effective manner. The process comprises a first chromatography using an anion exchange matrix, a second chromatography using hydroxyapatite and, optionally, a size exclusion chromatography. VLP preparations obtained by the process of the invention are essentially free of endotoxin contaminations. | 2009-02-19 |
20090048434 | Compositions and methods relating to orthogonal ribosome mRNA pairs - Orthogonal ribosome orthogonal mRNA pairs are provided, as are methods for their selection involving a novel positive-negative selection approach, and methods for their use. Also provided are cellular logic circuits involving orthogonal ribosomes. | 2009-02-19 |
20090048435 | Oligonucleotide modulation of cell adhesion - Compositions comprising oligonucleotides which are specifically hybridizable with nucleic acids encoding cellular adhesion molecules intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and endothelial leukocyte adhesion molecule-1 (ELAM-1) are disclosed. A series of double stranded RNA molecules targeting human ICAM-1 were designed and inhibition of RNA was measured. Oligonucleotides targeted to ICAM were effective in reducing airway hyperresponsiveness in mouse and monkey asthma models. | 2009-02-19 |
20090048436 | Methods of synthesizing chemically cleavable phosphoramidite linkers - The present invention provides a method of synthesizing phosphoramidite linkers that are useful for the production of synthesizing two or more oligonucleotides in tandem. The inventive linker has the following desirable properties: (i) enhanced stability to alkali conditions versus the linkers previously published, (ii) cleaves to produce 5′ and 3′ ends that are fully biologically compatible, (iii) cleaves completely under conditions that are already used in cleavage/deprotection processes so it is fully compatible with conditions that are common in laboratories and does not require additives that necessitate further purification after cleavage, (iv) integrates easily onto commercially available synthesizers because it is compatible with standard coupling chemistry, and (v) is compatible with DNA, RNA, forward, reverse, and LNA, synthesis chemistries. In addition, the inventive linkers may be coupled to a solid support. Thus, the inventive linkers provide a significant advancement in the state of the art. | 2009-02-19 |
20090048437 | METHOD OF PURIFYING RNA USING KOSMOTROPIC SALT - The present invention provides a method of purifying RNA, including contacting a solid support with an acidic solution having a RNA-containing sample and a kosmotropic salt having a concentration of less than 1M, thereby binding the RNA to the solid support. According to the present invention, RNA is purified efficiently due to high RNA yield and low contamination by DNA. The present invention is particularly effective in purifying RNAs of 200 nucleotides or less. | 2009-02-19 |
20090048438 | Method for washing a column and method for extracting membrane-bound target molecules - A method for washing a column is characterised by using a washing liquid, such as an eluting buffer, water, or even any expected buffer, between the traditional washing step and the eluting step as to effectively remove the impurities and/or residual washing liquid in a column from the previous washing step. A method for extracting membrane-bound target molecules containing the additional washing method is also devised. | 2009-02-19 |
20090048439 | Isolation of nucleic acids molecules using modified solid supports - Provided are solid supports that contain at least one hydrophilic ligand; and at least one hydrophobic ligand, where amount of the at least one hydrophobic ligand on the solid support relative to the amount of the at least one hydrophilic ligand on the solid support is adjusted for binding target nucleic acid(s) from a sample onto the solid support and/or for eluting the bound target nucleic acid(s) from the solid support, so that the amount of target nucleic acid(s) bound to the solid support and/or recovered after elution from the solid support is about 5% to about 500% greater than the amount of target nucleic acid(s) bound to the solid support and/or recovered from the solid support in the absence of either the at least one hydrophobic ligand or the at least one hydrophilic ligand or both. The solid supports with ligands are used for isolation of nucleic acid molecules from samples. | 2009-02-19 |
20090048440 | Nucleotide Sugar Purification Using Membranes - The invention provides methods of removing contaminants from a mixture of a desired product and contaminants by pH adjustments and molecular weight cut-offs. The contaminants include phosphate groups, magnesium sulfate, sodium pyruvate and tetrasodium pyrophosphate groups. The desired product includes nucleotide sugars, glycolipids, LnNT, sialyl lactose, and salts. | 2009-02-19 |
20090048441 | Process for the Preparation of Ezetimibe - The present invention relates to a cost effective and industrially advantageous process for the preparation of (3R,4S)-1-(4-Fluorophenyl)-3-[3(S)-3-(4-fluorophenyl)-3-hydroxypropyl)]-4-(4-hydroxyphenyl)-2-azetidinone, referred to here as Ezetimibe, it is represented as formula (1). | 2009-02-19 |
20090048442 | Novel compounds - Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors. | 2009-02-19 |
20090048443 | ARYL- AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN - The compounds of the present invention are represented by the chemical structure found in Formula (I): | 2009-02-19 |
20090048444 | Process for Preparing Pyrido[2,3-d]pyrimidin-7-one and 3,4-Dihydropyrimido[4,5-d]pyrimidin-2(1H)-one Derivatives - The present invention is directed to a novel method of preparing of 2,4,8-trisubstituted pyrido[2,3-d]pyrimidin-7-one pharmacophores of Formula (II) or (IIa) | 2009-02-19 |
20090048445 | Method of Synthesizing Quinoxaline Derivative by Microwave Irradiation - There is disclosed a method of synthesizing a quinoxaline derivative in which toxicity, corrosiveness and permeation are low and which is excellent in safety and which attains a reduced reaction time, a greatly improved yield and excellent economical efficiency. The object is achieved by a method of synthesizing a quinoxaline derivative which comprises adsorbing a benzofuroxan derivative and a β-diketone derivative on a solid support, and then heating the derivatives in a solid state by microwave irradiation to dehydrocyclize them. | 2009-02-19 |
20090048446 | Process For Producing Benzo[C]Phenanthridine Derivative - A compound represented by the following formula (1): [wherein R1 and R2 each independently represents hydroxy, provided that R1 and R2 may be bonded to each other to form methylenedioxy, etc.; X represents halogeno; and R3 represents a protective is subjected to a cyclization reaction with the aid of an organic silyl hydride and then aromatized with an oxidizing agent to produce a benzo [c] phenanthridine derivative represented by the following formula (2): [wherein R1, R2, and R3 have the same meanings as defined above]. | 2009-02-19 |
20090048448 | SALTS OF CYNNAMIDE COMPOUND OR SOLVATES THEREOF - The invention provides crystals of dihydrochloride monohydrate of the compound of the following formula having an Aβ production inhibiting effect which crystals are characterized by exhibiting a diffraction peak at an angle of diffraction (2θ±0.2°) of 10.9° in powder X-ray diffractometry. Further, the invention also provides the compound in the form of various salts, crystal forms and amorphous forms which are suitable for the development of drugs. | 2009-02-19 |
20090048449 | RIMONABANT MONOHYDRATE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME - The present invention relates to rimonabant monohydrate, to the process for preparing it and to the pharmaceutical compositions containing it. | 2009-02-19 |
20090048450 | Process for production of optically active cyclopropanecarboxylate compound - A process for production of an optically active cyclopropanecarboxylate compound represented by the formula (5): | 2009-02-19 |
20090048451 | Synthesis of triazole derivatives from Lewis base mediated nitroalkene-aldehyde coupling - In the present invention a method to synthesize a triazole derivative from a Lewis base mediated nitroalkene-aldehyde coupling is revealed. In this synthesis a nitroalkene is reacted with an aromatic aldehyde in the presence of a Lewis Base, NaN | 2009-02-19 |
20090048452 | SUBSTITUTED HYDANTOINS - This invention relates to compounds of formula I: | 2009-02-19 |
20090048453 | Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-p- yrrole-1-heptanoic acid - Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease. | 2009-02-19 |
20090048454 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof - Novel intermediates for the production of aminoacetyl pyrrolidine carbonitrile derivatives ensure the safe and efficient production of the compounds. Specifically, the present invention provides a sulfonyloxyacetyl pyrrolidine derivative, represented by the following formula: | 2009-02-19 |
20090048455 | Manufacture of Thiolactones - The present invention relates to a process for the manufacture of cyclic thio esters (thiolactones) and related compounds by hydrogenation of cyclic thioanhydrides in the presence of metal catalysts. | 2009-02-19 |
20090048456 | ACTIVATED SOLID SUPPORT AND METHOD - Disclosed is a method for activating a solid support material with epoxy groups and for immobilising ligands thereon, utilising phase transfer catalytic conditions. The method permits the introduction of epoxy groups and specific nucleophilic ligands on the support material with a high level of substitution. Furthermore, the invention provides a general method for immobilising a ligand for use in a wide variety of chromatographic separation procedures such as ion exchange chromatography, hydrophobic interaction chromatography (HIC), reverse phase chromatography (RPC), or affinity chromatography. | 2009-02-19 |
20090048457 | PROCESS FOR PREPARATION OF RACEMIC NEBIVOLOL - A process of making racemic [2S*[R*[R*[R*]]]] and [2R*[S*[S*[S*]]]]-(±)α,α′-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] of the compound of the formula (I) and its pure [2S*[R*[R*[R*]]]]- and [2R*[S*[S*[S*]]]]-enantiomer compounds and pharmaceutically acceptable salts thereof. | 2009-02-19 |
20090048458 | SYNTHESIS OF 2-HYDROXY-N,N-DIMETHYL-3-[[2-[[1(R)-(5-METHYL-2-FURANYL)PROPYL]AMINO]-3,4- -DIOXO-1-CYCLOBUTEN-1-YL]AMINO]BENZAMIDE - Disclosed is a process for making the compound of formula I: | 2009-02-19 |
20090048459 | METHOD OF MAKING HYDROGENATED METATHESIS PRODUCTS - Disclosed is a method of making hydrogenated metathesis products comprising the steps of: (a) providing a metathesis composition; (b) providing a metathesis catalyst comprising a transition metal; (c) metathesizing at least a portion of the metathesis composition in the presence of the metathesis catalyst to form a first composition comprising one or more metathesis products and a transition metal; (d) hydrogenating at least a portion of the first composition in the presence of a hydrogenation catalyst to form a second composition comprising one or more hydrogenated metathesis products, transition metal, and hydrogenation catalyst; and (e) removing at least a portion of the hydrogenation catalyst from the second composition, wherein the removal of the hydrogenation catalyst removes at least a portion of the transition metal of the metathesis catalyst from the second composition. | 2009-02-19 |
20090048460 | NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE - The present invention relates to a process for preparing a key intermediate of cefprozil and use of this intermediate in the preparation of cefprozil thereby avoiding impurity-causing self-acylation. | 2009-02-19 |
20090048461 | Regulators of Bacterial Signalling Pathways - The present invention provides a method for the preparation of compounds of formula (II). The invention also provides novel compounds of formula (II) and their use in medical, scientific and/or biological applications. | 2009-02-19 |
20090048462 | Method for producing biphenyltetracarboxylic acid - A method for producing a biphenyltetracarboxylic acid is to perform dimerization of a bromophthalate under the presence of a palladium catalyst and at least one reducing agent selected from the group consisting of saccharides and aliphatic monoalcohols having at least two carbon atoms. By this production method, since a side reaction is suppressed, a biphenyltetracarboxylic acid useful as a starting material for a polyimide resin having superior heat resistance and mechanical properties can be obtained in higher yield than ever. | 2009-02-19 |
20090048463 | Process for the manufacture of iohexol - A process for the production of iohexol comprises alkylating 5-Acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide using 2(2-methoxy-ethoxy)-ethanol as solvent in the presence of a base, and optionally isolating crude iohexol from the reaction mixture. Preferably, the alkylating agent is 1-chloro-2,3 propanediol and the base is an alkali metal hydroxide such as sodium hydroxide or potassium hydroxide. | 2009-02-19 |
20090048464 | Purification of armodafinil - The invention encompasses processes for obtaining pure armodafinil substantially free of disulfide impurities that is suitable for use on an industrial scale. In particular, a processes for purifying armodafinil from bis(diphenylmethyl)disulfide comprising: dissolving crude armodafinil in ethanol to form a solution; adding a solvent selected from the group consisting of linear or branched C | 2009-02-19 |
20090048465 | PROCESS FOR PREPARING 4-AMINODIPHENYLAMINE - A process for preparing 4-aminodiphenylamine having the steps of reacting nitrobenzene and aniline in the presence of a complex base catalyst, hydrogenating the reaction mixture with hydrogen, a powdery composite catalyst, and a hydrogenation solvent; separating, recovering, and reusing the complex base catalyst and the powdery composite catalyst from the reaction mixture; separating, recovering, and reusing aniline, and optionally water, from the reaction mixture; refining the reaction mixture to obtain 4-aminodiphenylamine. The complex base catalyst comprises tetraalkyl ammonium hydroxide, and tetraalkyl ammonium salt. | 2009-02-19 |
20090048466 | PROCESS FOR PREPARING AMINES BY CONDITIONING THE CATALYST WITH AMMONIA - The invention relates to a process for preparing amines by conditioning the catalyst with ammonia. | 2009-02-19 |
20090048467 | METHODS FOR MAKING IMMOBILIZED ARYL-CONTAINING LIGANDS - Organic ligands that contain at least one aryl group are immobilized on a solid support. The organic ligands are of the type used to form a catalyst complex suitable for carrying out a catalytic reaction, preferably an asymmetric reaction. To immobilize the organic ligands, a tethering group is bonded to the ligand using, for example, a Friedel-Crafts acylation or alkylation reaction. The immobilization of the organic ligand can be carried out using a single reaction with the organic ligand. | 2009-02-19 |
20090048468 | Method for the production of dimethyl ether - Provided is a process for the production of dimethyl ether. The process improves the effectiveness of the production of dimethyl ether. Especially, the process can be combined with processes for the production of methanol. | 2009-02-19 |
20090048469 | Iodine-containing fluoropolyether and process for producing the same - An iodine-containing fluoropolyether represented by the following general formula [I]: | 2009-02-19 |
20090048470 | Process for Producing Hydroxy Compound - The invention provides a process for producing a hydroxy compound comprising the following steps:
| 2009-02-19 |
20090048471 | Production Process of 1,6-Hexanediol - A method is provided for obtaining highly pure 1,6-hexanediol in which the contents of impurities such as 1,4-cyclohexanediol, 1,5-hexanediol, 1,2-cyclohexanediol, 1,7-pentanediol, 1,5-pentanediol and high boiling point components are significantly reduced. | 2009-02-19 |
20090048472 | METHOD FOR PURIFICATION OF GLYCEROL FROM BIODIESEL PRODUCTION - A method for purification of crude glycerol, especially crude glycerol derived from biodiesel production using alkaline catalysts. The method comprises combining the crude glycerol with acid, separating a glycerol layer, and treating the glycerol layer to decolorize it. | 2009-02-19 |
20090048473 | ITQ-34, new crystalline microporous material - ITQ-34 (INSTITUTO DE TECNOLOGÍA QUÍMICA number 34) is a new crystalline microporous material with a framework of tetrahedral atoms connected by atoms capable of bridging the tetrahedral atoms, the tetrahedral atom framework being defined by the interconnections between the tetrahedrally coordinated atoms in its framework. ITQ-34 can be prepared in silicate compositions with an organic structure directing agent. It has a unique X-ray diffraction pattern, which identifies it as a new material. ITQ-34 is stable to calcination in air, absorbs hydrocarbons, and is catalytically active for hydrocarbon conversion. | 2009-02-19 |
20090048474 | Reactive distillation with olefin recycle - The present invention relates to a process for the production of alkene(s) from a feedstock comprising of at least one monohydric aliphatic paraffinic alcohol in a reactive distillation reactor with olefin recycle. | 2009-02-19 |
20090048475 | Olefin production utilizing a feed containing condensate and crude oil - A method for utilizing a feed comprising condensate and crude oil for an olefin production plant is disclosed. The feed is subjected to vaporization and separated into vaporous hydrocarbons and liquid hydrocarbons. The vaporous hydrocarbons stream is thermally cracked in the plant. The liquid hydrocarbons are recovered. | 2009-02-19 |
20090048476 | Catalyst-Loaded Coal Compositions, Methods of Making and Use - The present invention relates to catalyst-loaded coal compositions having a moisture content of less than about 6 wt %, a process for the preparation of catalyst-loaded coal compositions, and an integrated process for the gasification of the catalyst-loaded coal compositions. The catalyst-loaded coal compositions can be prepared by a diffusive catalyst loading process that provides for a highly dispersed catalyst that is predominantly associated with the coal matrix, such as by ion-exchange. | 2009-02-19 |
20090048477 | Hydrocracking Catalyst, and Method for Production of Fuel Base Material - A hydrocracking catalyst that solves the above-described problem comprises a carrier containing ultra-stable Y-type zeolite obtained by the ultrastabilization of NaY-type zeolite and a metal from group VIII of the Periodic Table supported on this carrier, and is characterized in that the NaY-type zeolite has a peak in its X-ray diffraction pattern in the range of 2θ=28.0° to 28.5° and 2θ=15.0° to 16.0°, and the intensity ratio I | 2009-02-19 |
20090048478 | Method for transporting radiation, applicator as well as radiation therapy device - Among other things, a method for transporting radiation to a body region is described, wherein, in a first step, a canal is formed up to the body region to be irradiated and wherein, in a second step, an applicator ( | 2009-02-19 |
20090048479 | Implant for supporting the urethra of a man and a surgical kit for treating incontinence in a man and including such an implant - The implant ( | 2009-02-19 |
20090048480 | CARDIAC HARNESS DELIVERY DEVICE - An apparatus for delivering a cardiac harness onto a heart includes an elongate body and a plurality of elongate push rods longitudinally movable with respect to the elongate body. The elongate body has a tubular housing that is sized to contain the cardiac harness which is removably attached to the push rods. The cardiac harness is releasably attached to the push rods such that advancement of the push rods in a distal direction moves the cardiac hearness from a compacted configuration in the housing to an expanded configuration outside the housing. A deflector is attached to the elongate body and is configured to flare radially outwardly. As the push rods advance out of the housing, the push rods slide over the deflector to more easily and safely advance over the enlarged heart and position the cardiac harness over the heart. | 2009-02-19 |
20090048482 | Image-based Path Planning for Automated Virtual Colonoscopy Navigation - A method for automatic virtual endoscopy navigation, including: (a) using a fisheye camera to generate an endoscopic image and a depth image from a current position of the camera in lumen computed tomographic (CT) data; (b) segmenting a first region and a second region from the depth image, wherein the first region identifies a view direction of the camera and the second region is an area through which the camera can be moved without touching an inner surface of the lumen; (c) moving the camera from the current position, while pointing the camera in the view direction, to a next position in the second region; and (d) repeating steps (a-c) in sequence using the next position in step (c) as the current position in step (a). | 2009-02-19 |
20090048483 | DEVICE FOR INSERTION GUIDE AND ENDOSCOPE HAVING THE SAME - A colonoscope as an endoscope has an insertion tube for insertion in a patient's gastrointestinal tract. A head portion is disposed at an end of the insertion tube, for inspecting a large intestine. In combination with this, a device for insertion guide includes a base tube mounted on the head portion. Two propulsion fins are disposed on the base tube to extend in an axial direction of the head portion. A driving mechanism with balloons shifts the propulsion fins between closed and open positions. The propulsion fins, when in the closed position, are disposed to extend along the head portion, and when in the open position, are deployed in a radial direction by setting a distal fin end thereof away from the head portion, to propel the head portion inserted in the large intestine. Furthermore, the balloons set the propulsion fins in the open position alternately with one another. | 2009-02-19 |
20090048484 | Device, system and method for magnetically maneuvering an in vivo device - A method for controlling movement of an imaging device in vivo, the method comprising the steps of providing an imaging device having a longitudinal axis and a magnetic component, said device to be inserted into a patient's body; providing a rotating magnetic field outside the patient's body; and advancing the rotating magnetic filed along the patient's body in a desired direction. | 2009-02-19 |
20090048485 | ENDOSCOPIC CUTTING INSTRUMENTS HAVING IMPROVED CUTTING EFFICIENCY AND REDUCED MANUFACTURING COSTS - The present invention is directed to improving the cutting efficiency and reducing the manufacturing costs associated with endoscopic cutting instruments by eliminating the distal bearing surfaces or providing means for making the contact at the distal bearing intermittent so that surfaces do no undergo high localized heat and galling. In one embodiment, this goal is achieved by modifying or removing the axial constraints on the inner sliding member that are characteristic of conventional endoscopic shavers. In another embodiment, the improved cutting efficiency and reduced manufacturing cost is achieved by eliminating a closed end characteristic of conventional endoscopic shavers (e.g., removing the closed end of either the inner sliding member or the outer sliding member to thereby eliminate the associated bearing surface formed therebetween). | 2009-02-19 |
20090048486 | Distal Tip for an Endoscope - A system configured for endoscopic treatment of tissue is provided. The system includes an elongate shaft having a proximal portion, a distal portion and a working channel extending at least partially through the shaft. The elongate shaft further includes a longitudinally extending central axis. A distal end of the distal portion of the elongate shaft includes a distal tip having a curvilinear portion. The curvilinear portion is configured to dilate a stricture in a gastrointestinal tract for passing a portion of the system through the stricture to the tissue. The distal tip includes a working channel port connected to the working channel. | 2009-02-19 |
20090048487 | TREATMENT DEVICE - A treatment device according to the present invention includes: an elongated sheath having flexibility, the sheath being passed through an endoscope and introduced to an object to be treated; an incision knife section disposed approximately along an axial line of the sheath around an outer periphery at the distal end thereof, the incision knife section being used for incising tissue of the object to be treated; and a rotation-torque-transmitting section extending from a proximal end of the elongated sheath maneuvered by an endoscopist to an intermediate section of the incision knife section in the axial line direction, the rotation-torque-transmitting section rotating the sheath by transmitting rotation torque input at the proximal end of the sheath. | 2009-02-19 |
20090048488 | ENDOSCOPE - There is provided an endoscope capable of obtaining operability for changing a shape of a bending portion and improving responsiveness. | 2009-02-19 |
20090048489 | MEDICAL APPARATUS OBTAINING INFORMATION INDICATIVE OF INTERNAL STATE OF AN OBJECT BASED ON INTERACTION BETWEEN ULTRASOUND WAVES AND LIGHT - In a medical apparatus, an ultrasound generator generates ultrasound waves to be radiated into the region, and an ultrasound radiating-direction changing member changes in the region a radiating direction of the ultrasound waves to be generated by the ultrasound generator. An ultrasound converging member converges in the region the ultrasound waves subjected to the change of the radiating direction. Light which is reachable to the region is emitted from a light source unit. A light transmitting/receiving member radiates light emitted from the light source unit and receives light reflected in a converged region of the ultrasound waves in the region. Based on the reflected light, information showing the internal state in a desired deeper region in the membrana mucosa of the body tissue of the object. | 2009-02-19 |
20090048490 | ENDOSCOPE - An endoscope of the present invention includes an insertion section including a distal end portion, an objective lens placed in the distal end portion, an illumination lens which is placed in the distal end portion adjacently to the objective lens and emits illumination light from a light source, and a wall portion which is placed between the objective lens and the illumination lens, and shields the illumination light, and thereby, secures a sufficient illumination range for an image pickup range with a wide field of view, can obtain a favorable endoscope image and can reduce the diameter. | 2009-02-19 |
20090048491 | METHOD AND APPARATUS FOR LAPAROSCOPIC RETRACTION - Extraluminal and intraluminal devices and methods, and laparoscopic instrumentation, dramatically improve laparoscopic retraction of both the small and large intestine. A scaffolding external to or within a selected segment or segments of small and/or large bowel is created, allowing for the retraction of the entire selected segment or segments of bowel via grasping either the device or supported bowel wall with a laparoscopic instrument or instruments. The devices may be designed and placed in a modular fashion, with the surgeon building the final scaffolding intra-operatively, or the scaffolding may be manufactured or pre-assembled prior to intra-operative use. | 2009-02-19 |
20090048492 | METHOD FOR MANAGING MULTIPLE PATIENT MONITORING SENSORS - A method for associating a plurality of patient monitoring sensors with an appropriate patient is disclosed herein. The method includes estimating a sensor location for each of a plurality of sensors that are operatively connected to a patient, transmitting the sensor location estimate from each of the sensors to a wireless device such that the sensor location estimate does not pass through an on-patient hub before reaching the wireless device, and implementing the sensor location estimate to assign each of the sensors that are disposed within a predefined region to a single patient. | 2009-02-19 |
20090048493 | Health and Entertainment Device for Collecting, Converting, Displaying and Communicating Data - A method for integrating and managing data is provided that includes interacting with an end user via a health and entertainment device, the device including: an accelerometer that is operable to track activity data by the user and a music module operable to play music for the user. The device further includes a memory and a processor operable to convert data from the accelerometer into one or more metrics based on data received from the memory. | 2009-02-19 |
20090048494 | Recording Apparatus, Reproducing Apparatus, Recording and Reproducing Apparatus, Recording Method, Reproducing Method, Recording and Reproducing Method, and Record Medium - Changes of a user's emotion that occurs when content is reproduced and a user's surrounding environment that occurs when the content is reproduced are recorded as sensing meta data and content is reproduced in a reproducing mode corresponding to the recorded sensing meta data. Content supplied from a content providing section | 2009-02-19 |
20090048495 | APPLICATION IDENTIFICATION SENSOR - An application identification sensor comprises a plurality of emitters configured to transmit light into a tissue site and a detector configured to receive the light after tissue absorption. The detector generates a signal responsive to the intensity of the light and communicates the signal to a monitor. An information element is readable by the monitor so as to identify a sensor application. The monitor presets at least one user-selectable operational parameter in response to the information element. | 2009-02-19 |
20090048496 | Method And Apparatus For Recording And Presentation Of Physiological Data - The invention relates to a method and device for recording and presentation of physiological parameters, which can include both blood pressure and heart pulse. Information about the heart pulse is derived from a recorded blood pressure signal, whereby the need for e.g. an external ECG measurement device is eliminated. It is likewise a part of the invention that a blood pressure measurement is used for the derivation of data such as Heart Rate Variability (HRV) and/or baroreflex sensitivity (BRS) values | 2009-02-19 |
20090048497 | Dynamically variable filter - A method of processing a signal pertaining to at least one electrical property of an organ of a subject is disclosed. The method comprises determining a physiological condition of the subject, selecting a frequency band, filtering the signal according to the frequency band, and dynamically adapting the frequency band in response to a change in the physiological condition. | 2009-02-19 |
20090048498 | System and method of monitoring an animal - A system and method for monitoring an animal is disclosed. In particular, an ingestible bolus configured to be maintained in the stomach of an animal is disclosed where the bolus comprises a sensor to monitor physiological and other characteristics of the animal. The bolus comprises a data transmitter in wireless communication with a base station and/or transponder in communication with a base station. Within the animal stomach, the bolus may be generally disposed in either a first orientation or second orientation. The base station and/or transponder comprises a plurality of antennae each having an orientation corresponding to a likely orientation of the bolus within the animal in order to reduce the power requirements of the bolus and increase its operational range. The base station may be configured to receiving incoming signals on each of the antennae and may combine the signals into a single input signal. | 2009-02-19 |
20090048499 | Sensor film for transcutaneous insertion and a method for making the sensor film - There is provided a thin film ( | 2009-02-19 |
20090048500 | METHOD FOR USING A NON-INVASIVE CARDIAC AND RESPIRATORY MONITORING SYSTEM - A non-invasive monitoring system using radiated energy to identify cardiac and respiratory waveforms in patients is discussed. The monitoring system illuminates a subject in radiated energy and then detects the reflected radiated energy caused by respiratory and/or cardiac functions. The detected reflections are used to plot a two-dimensional waveform. The waveforms represent the rise and fall of a detected signal (the reflected energy) over time and are indicative of the small movements of the patient's chest and abdomen that are associated with cardiac and respiratory function. Different implementations of the monitoring system use laser or ultrasonic energy to capture breathing and cardiac waveforms for analysis. The waveforms may be used to diagnose the effectiveness of prescribed sleep medication, perform remote line of sight monitoring from a remote location, identify crying waveforms for babies and infants, identify cardiac waveforms in a non-invasive manner and identify seizure and tremor activity. | 2009-02-19 |
20090048501 | Glucose measuring device integrated into a holster for a personal area network device - A glucose meter module integrated into a holster device that can securely accommodate another device such as a portable server device or an insulin pump is described. The glucose measuring module and the health device communicate with each other by a short range wireless modality. In the case in which the accommodated device is a server, such as personal digital assistant or cell phone, the device stores data in a memory, displays data on a visual display, and can wirelessly transmit such data to other devices within a personal area network. In the case where the accommodated device is a cell phone, the phone can further transmit data to remote sites. In the case where the accommodated device is an insulin pump, wirelessly received data are stored in a memory, are available for visual display on the insulin pump, and can be incorporated into the electronic processes that regulate the performance of the pump. | 2009-02-19 |
20090048502 | Broadband illuminator for oximetry, hemoglobin, met-hemoglobin, carboxy-hemoglobin, and other blood component monitoring - An ischemia detection system in two or more somatic measures, collected simultaneously or near-simultaneously, are provided for direct or computational comparison, in which light from light source A ( | 2009-02-19 |
20090048503 | GLYCEMIC CONTROL MONITORING USING IMPLANTABLE MEDICAL DEVICE - An apparatus for monitoring a patient's blood glucose level. The apparatus includes an implantable medical device having a controller and an implantable heart sounds sensor configured to transmit signals to the controller of the implantable medical device. The controller is configured to determine if a patient is hypoglycemic or hyperglycemic based on the signals from the heart sounds sensor. A method is also disclosed that includes sensing the patient's heart sounds, determining the amplitude of the S2 heart sound, determining the length of the interval from the S1 heart sound to the S2 | 2009-02-19 |
20090048504 | Medical electrode systems and methods - Systems, methods, and devices are provided for creating and applying electrodes and electrode systems to a wound or skin. An electrode may be applied as a single electrode strip using a dispenser. An electrode may also be cut to size from a single sheet of electrode. Additionally, an electrode may be formed from a plurality of electrode segments which may be connected together. Electrodes can also be incorporated as part of drainage tubes. A medical electrode kit may be provided that includes multiple electrode segments and connectors, multiple electrodes, and multiple control modules. In addition, electrodes or electrode systems may be provided with a color scoring chart. An electrode system may be configured to interface with a selected body part. Electrode systems may include sensors and electrodes configured for application to areas outside of a wound or the skin intended to be treated. | 2009-02-19 |
20090048505 | Upper body MRI scanner and associated control method - The invention relates to an upper body MRI scanner comprising a magnet arrangement for producing a horizontally oriented homogeneous main magnetic field, said magnet arrangement being designed to examine the upper body of a standing patient. An image acquisition unit is provided for continuously creating upper body images of the standing patient. A quality checking unit is designed for automatically determining a quality metric characterizing the quality of the upper body images. An imaging controller connected to the image acquisition unit and the quality checking unit is provided for activating the image acquisition unit and outputting signals for influencing the position and/or behavior of the patient as a function of the characteristic quality metric. An output unit connected to the image acquisition unit is used for displaying and/or storing at least some of the upper body images. | 2009-02-19 |
20090048506 | METHOD AND SYSTEM FOR ASSESSING BRAIN FUNCTION USING FUNCTIONAL MAGNETIC RESONANCE IMAGING - A system for assessing brain functioning uses neuropsychological assessments which are performed while a patient is within an fMRI scanning environment and while scanning is in process to detect the BOLD signals within the patient's brain. The system may be used to detect brain impairment and injuries which do not present tissue damage detectable using previous methods. | 2009-02-19 |
20090048507 | Method and apparatus for imaging functional and electrical activities of the brain - A method and an apparatus for imaging functional and electrical activities of the brain are disclosed. In order to allow improved relative positional determination of the epileptogenic focus with reference to the EEG electrodes, a positron emission tomography measurement using at least one radiation detector, and a magnetic resonance imaging measurement using at least one coil for generating a basic magnetic field, at least one gradient coil and a radio-frequency antenna device are undertaken in at least one embodiment. In addition, in at least one embodiment an electroencephalography measurement using a plurality of electrodes for acquiring spatial and temporal changes of the electrical activities of the brain and a computed tomography measurement using at least one x-ray source and at least one x-ray detector are carried out. By way of an evaluation apparatus in at least one embodiment, a spatial correlation between the computed tomography measurement and the magnetic resonance imaging measurement is undertaken, so as to result in registration between the electroencephalography measurement and the positron emission tomography measurement. | 2009-02-19 |
20090048508 | Rf coil assembly for use in magnetic resonance imaging - An RF coil assembly for use with magnetic resonance imaging (MRI) apparatus is described. The RF coil assembly comprises one or more coil elements capable of receiving electromagnetic radiation and is capable of being directly attached to a stereotactic base ring. The RF coil assembly may comprise a localiser box having fiducial markers. A corresponding attachment apparatus is also described for optimising the attachment position of a stereotactic base ring to a subject's head. The attachment apparatus comprises one or more fixing elements that allow the attachment apparatus to be releasably attached to a stereotactic base ring. In one embodiment, the internal dimensions of the attachment apparatus are selected to be substantially the same as the internal dimensions of an RF coil assembly. Corresponding methods are also described. | 2009-02-19 |
20090048509 | SHIELDED SURGICAL NAVIGATION SYSTEM THAT DETERMINES THE POSITION AND ORIENTATION OF THE TRACKED OBJECT WITH REAL AND VIRTUAL DIPOLES - A system for determining the position and orientation of a tracked object by measuring electromagnetic energy. The system includes a shield of magnetic permeable material positioned on one side of the object to be tracked. A transmitter emits the electromagnetic energy and there is a tracker sensor. One of the transmitter or tracker sensor is attached to the object to be tracked. A correction sensor is at fixed location relative to the transmitter assembly. Both sensors assemblies measure the electromagnetic energy emitted by the transmitter. Based on the energy measured by the correction sensor, the location of a virtual dipole that mirrors the transmitter, the real dipole, on the opposite side of the shield is determined. Based on the positions of the real and virtual dipoles and the energy measured by the tracker sensor, the position and orientation of the tracker sensor relative to the transmitter is determined. | 2009-02-19 |
20090048510 | Fiducial Marker for Correlating Images - The invention relates to a fiducial marker having a marking grid that is used to correlate and view images produced by different imaging modalities or different imaging and viewing modalities. More specifically, the invention relates to the fiducial marking grid that has a grid pattern for producing either a viewing image and/or a first analytical image that can be overlaid with at least one other second analytical image in order to view a light path or to image different imaging modalities. Depending on the analysis, the grid pattern has a single layer of a certain thickness or at least two layers of certain thicknesses. In either case, the grid pattern is imageable by each imaging or viewing modality used in the analysis. Further, when viewing a light path, the light path of the analytical modality cannot be visualized by viewing modality (e.g., a light microscope objective). By correlating these images, the ability to analyze a thin sample that is, for example, biological in nature but yet contains trace metal ions is enhanced. Specifically, it is desired to analyze both the organic matter of the biological sample and the trace metal ions contained within the biological sample without adding or using extrinsic labels or stains. | 2009-02-19 |
20090048511 | Catheter For Media Injection - An improved endocardial catheter includes a plurality of longitudinally extending openings adjacent intermediate portions at its distal end. The catheter is actuable from a retracted or collapsed mode, wherein the sealed openings are arranged around the tubular catheter surface, to an expanded mode. The plurality of longitudinal openings in the catheter wall enable radial expansion of the tubular surface at the distal end so that intermediate portions of the tubular catheter surface are moved to an operative position radially outward from their position in the retracted mode. In the expanded position, the intermediate portions form wings around the distal end, revealing a cavity within the tubular catheter for the release of contrast material or other fluid into endocardial sites through the longitudinal openings. | 2009-02-19 |