08th week of 2012 patent applcation highlights part 40 |
Patent application number | Title | Published |
20120046333 | Methods and Compositions of PI-3 Kinase Inhibitors for Treating Fibrosis - Methods and compositions of PI-3 kinase inhibitors and their use in inhibiting PI-3 kinase activity in mammals and the treatment of fibrosing syndromes in a subject are described herein | 2012-02-23 |
20120046334 | PYRROLIDINE-SUBSTITUTED FLAVONES AS RADIO-SENSITIZERS FOR USE IN THE TREATMENT OF CANCER - The present invention relates to a combination for the treatment of cancer wherein the combination exhibits a synergistic effect. The combination comprises radiation and at least one cyclin dependent kinase (CDK) inhibitor selected from the compounds of formula I or a pharmaceutically acceptable salt or a solvate thereof. The present invention also relates to a method for the treatment of cancer, which method comprises administering to a patient in need of such a treatment, a therapeutically effective amount of the combination. The present invention also relates to the use of a CDK inhibitor selected from the compounds of formula I as a radiosensitizer that enhances the efficacy of radiotherapy for the treatment of cancer, particularly head and neck cancer. | 2012-02-23 |
20120046335 | SOLID STATES OF ATORVASTATIN POTASSIUM - Atorvastatin potassium crystalline Forms A, B, E, F, and G are provided. Also provided are methods of preparing atorvastatin potassium crystalline Forms A, B, E, F, and G. Atorvastatin potassium crystalline Forms A, B, E, F, and G may be used to prepare pharmaceutical compositions useful for the treatment of hypercholesterolemia or hyperlipidemia. | 2012-02-23 |
20120046336 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION - This invention relates to treating age-related cognitive impairment. This invention in particular relates to the use of inhibitors of synaptic vesicle protein 2A (SV2A), such as levetiracetam, seletracetam, and brivaracetam, in improving cognitive function in subjects that exhibit age-related cognitive impairment or are at risk thereof, including, without limitation, subjects having or at risk for Mild Cognitive Impairment (MCI), Age-related Cognitive Decline (ARCD) or Age-Associated Memory Impairment (AAMI). | 2012-02-23 |
20120046337 | Novel Five-Membered Iminocyclitol Derivatives as Selective and Potent Glycosidase Inhibitors: New Structures for Antivirals and Osteoarthritis Therapeutics - Novel 5-membered iminocyclitol derivatives were found to be a potent and selective inhibitors of the glycoprotein processing α- and β-glucosidase which were further found to be active antiviral agents against Japanese encephalitis virus, dengue virus serotype 2 (DEN-2), human SARS coronavirus and human β-hexosaminidase, a new target for development of osteoarthritis therapeutics. | 2012-02-23 |
20120046338 | FUSED CYCLIC COMPOUNDS - The present invention provides a compound represented by the formula (I): | 2012-02-23 |
20120046339 | Novel chorismate mutase gene from the potato cyst nematode globodera rostochiensis - The nucleotide sequence of a 992 bp region of cDNA and the nucleotide sequence of a 1973 bp (or a 1913 bp) of genomic DNA of the Gr-cm-1 gene were determined for | 2012-02-23 |
20120046340 | Down Regulation of the Gene Expression by Means of Nucleic Acid-Loaded Virus-Like Particles - The present invention relates to compositions of virus-like particles for the introduction of RNA-interference (RNAi-) inducing molecules into eukaryotic cells and methods for the cell type-specific transduction of a plurality of eukaryotic cells with RNAi-inducing molecules. The present invention furthermore relates to methods for a diagnosis, prevention and/or treatment of diseases or disease states associated with an increased expression rate of at least one endogenous gene, and/or with the undesired expression of at least one endogenous gene and/or foreign nucleic acids, in particular viral nucleic acids. | 2012-02-23 |
20120046341 | FUS/TLS-BASED COMPOUNDS AND METHODS FOR DIAGNOSIS, TREATMENT AND PREVENTION OF AMYOTROPHIC LATERAL SCLEROSIS AND RELATED MOTOR NEURON DISEASES - The invention provides novel FUS/TLS nucleic acids and proteins that comprise one or more genetic markers (for example, single nucleotide polymorphisms) and methods of use thereof including methods relating to the diagnosis of ALS or other related motor neuron disease by virtue of the presence of the mutant FUS/TLS sequence(s). | 2012-02-23 |
20120046342 | OLIGONUCLEOTIDE COMPRISING AN INOSINE FOR TREATING DMD - The invention provides an oligonucleotide comprising an inosine, and/or a nucleotide containing a base able to form a wobble base pair or a functional equivalent thereof, wherein the oligonucleotide, or a functional equivalent thereof, comprises a sequence which is complementary to at least part of a dystrophin pre-m RNA exon or at least part of a non-exon region of a dystrophin pre-m RNA said part being a contiguous stretch comprising at least 8 nucleotides. The invention further provides the use of said oligonucleotide for preventing or treating DMD or BMD. | 2012-02-23 |
20120046343 | MULTI-TARGETING SHORT INTERFERING RNAs - The present invention relates to novel short interfering RNA (siRNA) molecules that are multi-targeted. More specifically, the present invention relates to siRNA molecules that target two or more sequences. In one embodiment, multi-targeting siRNA molecules are designed to incorporate features of siRNA molecules and features of micro-RNA (miRNA) molecules. In another embodiment, multi-targeting siRNA molecules are designed so that each strand is directed to separate targets. | 2012-02-23 |
20120046344 | TREATMENT OF LIPID TRANSPORT AND METABOLISM GENE RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A LIPID TRANSPORT AND METABOLISM GENE - The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Lipid transport and metabolism gene, in particular, by targeting natural antisense polynucleotides of a Lipid transport and metabolism gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of a Lipid transport and metabolism genes. | 2012-02-23 |
20120046345 | TREATMENT OF DYSTROPHIN FAMILY RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO DMD FAMILY - The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Dystrophin family, in particular, by targeting natural antisense polynucleotides of Dystrophin family. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of DMD family. | 2012-02-23 |
20120046346 | SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF - Described herein are synthetic, modified RNAs for changing the phenotype of a cell, such as expressing a polypeptide or altering the developmental potential. Accordingly, provided herein are compositions, methods, and kits comprising synthetic, modified RNAs for changing the phenotype of a cell or cells. These methods, compositions, and kits comprising synthetic, modified RNAs can be used either to express a desired protein in a cell or tissue, or to change the differentiated phenotype of a cell to that of another, desired cell type. | 2012-02-23 |
20120046347 | EXPRESSION OF APOAI AND VARIANTS THEREOF USING SPLICEOSOME MEDIATED RNA TRANS-SPLICING - Methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated RNA trans-splicing that result in expression of a apoAI protein, an apoAI variant, the preferred embodiment referred to herein as the apoAI Milano variant, a pre-pro-apoAI or an analogue of apoAI. The methods and compositions include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and mediate a trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (chimeric RNA) capable of encoding apoAI, the apoAI Milano variant, or an analogue of apoAI. The expression of this apoAI protein results in protection against vascular disorders resulting from plaque build up, i.e., atherosclerosis, strokes and heart attacks. | 2012-02-23 |
20120046348 | OLIGONUCLEOTIDE CHELATE COMPLEXES - The present disclosure describes the broadly active chelation of diverse divalent 2+ metal cations by any oligonucleotide (ON), regardless of size or modification. This chelation effect is specific to cations which are divalent (or of higher valency) and results in the formation of oligonucleotide chelate complexes which do not behave like salts. It is described herein a novel composition of an ON chelate complex prepared using any ON and a divalent metal cation and methods for the suppression of anti-coagulation and or subcutaneous injection site reactions and or improved tolerability with oligonucleotides by the use of ON chelate complexes during oligonucleotide administration. | 2012-02-23 |
20120046349 | COMPOSITIONS FOR TARGETING CONDUCTING AIRWAY CELLS COMPRISING ADENO-ASSOCIATED VIRUS CONSTRUCTS - An artificial AAV capsid comprising a heterologous conducting airway targeting sequence is provided. The artificial AAV is useful as a targeting moiety, for delivery of heterologous molecules which are associated therewith. The artificial AAV is also useful in the generation of AAV vectors having the artificial capsid. Also described are methods of modifying the native tropism and transduction efficiency of vectors by improving and/or ablating their ability to transduce conducting airway cells. Methods of targeting conducting airway cells and delivering therapeutic and other molecules thereto are also provided. | 2012-02-23 |
20120046350 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE - Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPARδ suptype. | 2012-02-23 |
20120046351 | Medicinal cannabis added in food - The invention is a product and a process wherein cannabinoids such as Medicinal Δ | 2012-02-23 |
20120046352 | Controlled cannabis decarboxylation - The invention is a process for the controlled decarboxylation of cannabis wherein Medicinal Delta-9 tetrahydrocannabinol (Δ | 2012-02-23 |
20120046353 | CLEISTOCALYX OPERCULATUS-DERIVED COMPOUNDS HAVING INHIBITORY ACTIVITIES AGAINST AVIAN AND SWINE INFLUENZA VIRUSES OR NOVEL INFLUENZA VIRUS - The present invention relates to a | 2012-02-23 |
20120046354 | ANTI-OXIDANT LOZENGES FOR THE PREVENTION AND TREATMENT OF RADIATION INDUCED MUCOSITIS, PRECANCEROUS LESIONS, ORAL CANCER AND OTHER ORAL CAVITY MUCOSAL DISORDERS - A method for treating or preventing oral cavity mucosal disorders, comprising a step of providing a lozenge containing an antioxidant selected from the group of Vitamin A, Vitamin C, Vitamin E; and other ingredients and a step of placing the lozenge within the oral cavity for a period of time required for dissolution of the lozenge. | 2012-02-23 |
20120046355 | INHIBITORS OF SIALIDASE OR SIALIDASE-LIKE ENZYMES - The present invention describes compounds of Formula I or a pharmaceutically acceptable salts or derivatives thereof. Compositions comprising compounds of Formula I are also described. The present invention further relates to a method of producing non-2-enonate compounds. | 2012-02-23 |
20120046356 | NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS - There is provided a process for the preparation of a compound of formula (III), wherein X and Y are as described in the description. Such compounds may, for example, be useful intermediates in the synthesis of drugs such as Dronedarone. There is also provided a process for the preparation of a compound of formula (I). | 2012-02-23 |
20120046357 | Benzamide and Napthamide Derivatives Inhibiting Nuclear Factor-Kappa (B) - (NK-kB) - The invention relates to compounds of formula (1) and formula (2), | 2012-02-23 |
20120046358 | USE OF ISOTHIOCYANATES COMPOUNDS IN TREATING PROSTATIC DISEASES AND SKIN CANCER - A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof. | 2012-02-23 |
20120046359 | Bed bug control and repellency - Control or repellency of bed bugs by bringing the bed bugs into contact with a bed bug control formulation containing at least one compound selected from the group consisting of certain alkyl ketones and cyclic ketones wherein the total number of carbon atoms in the alkyl ketones and cyclic ketones is from 10 to 16 carbon atoms and method for achieving such control or repellency. | 2012-02-23 |
20120046360 | FORMULATION COMPRISING FENOFIBRIC ACID, A PHYSIOLOGICALLY ACCEPTABLE SALT OR DERIVATIVE THEREOF - A formulation comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients is described. Fenofibric acid, the physiologically acceptable salt or derivative thereof is preferably in the form of a molecular dispersion in these formulations. An advantageous process for their preparation, in particular by melt extrusion, and the use of this formulation for oral administration of fenofibric acid, a physiologically acceptable salt or derivative thereof are likewise described. | 2012-02-23 |
20120046361 | ETHYL PYRUVATE COMPOSITIONS AND METHODS - Compositions and methods are disclosed for use of ethyl pyruvate to boost energy, endurance, or to feel good, or to lose weight. Pharmaceutical preparations having ethyl pyruvate are disclosed herein as well. | 2012-02-23 |
20120046362 | ANTIVIRAL AGENT AND CLEANSING AGENT - It is an object to provide an antiviral agent that can be used for persons having sensitive skin or on the face, inactivates viruses such as a norovirus and an influenza virus, and is excellent in germicidal properties. Further provided is a cleansing agent that does not lead to environmental pollution since the cleansing agent is easily decomposed in the natural environment, scarcely causes eczema and allergic dermatitis since no germicidal agent is added, and has an antiviral performance. The antiviral agent containing a surface-active agent having a C18 unsaturated alkyl group as an active component. It is not always necessary to lather or rinse off with water like cleansing agents such as medicated soaps since the antiviral agent of the present invention at a very low concentration can inactivate the virus. | 2012-02-23 |
20120046363 | DOCOSAHEXAENOIC ACID FOR THE TREATMENT OF HEART FAILURE - There is currently no completely effective treatment for heart failure. Considering the need for, and current void in the medical field for, a treatment for heart failure, the invention is drawn to treating heart failure. In particular aspects, the invention is drawn to the discovery that certain polyunsaturated fatty acids (PUFAs) and doses thereof are useful for treating heart failure. In other particular aspects, the invention is drawn to the discovery that certain PUFAs and doses thereof are useful for preserving mitochondrial function in a heart failure subject. | 2012-02-23 |
20120046364 | Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use - The present invention relates to sulfonic acid containing compounds of formula IB, in which G, R | 2012-02-23 |
20120046365 | Method and Composition for Administering an NMDA Receptor Antagonist to a Subject - The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject. | 2012-02-23 |
20120046366 | Extractions of Fixed Oil and Thymoquinone Rich Fractions (TQRF) - The present invention reported that SFE is suitable for | 2012-02-23 |
20120046367 | ESSENTIAL OIL COMPOSITION WITH ANTI-FREE RADICAL ABILITY - Disclosed is an essential oil composition with anti-free radical ability, which includes dl-Citronellol, Eugenol, cis/trans-Citral, Eugenol Methyl Ether and Thymol. It is confirmed that the essential oil composition of the present invention has superior anti-free radical ability and anti-oxidative ability according to the indices including DPPH free radical scavenging ability, ABTS | 2012-02-23 |
20120046368 | METHOD FOR PURIFYING 3,4-DIHYDROXYPHENYLGLYCOL (DHPG) FROM PLANT PRODUCTS - Process for purifying 3,4-dihydroxyphenylglycol (DHPG) from any part of the plant, from the products or by-products derived from olive trees or any other vegetable product of the families Oleaceae, Orobanchaceae, Plantaginaceae, Compositae, Lamiaceae, Acanthaceae and/or Scrophulariaceae, and which comprises 1 or more steps wherein the initial product is introduced into at least one ion-exchange resin column, and in potentially subsequent steps the product eluted in the preceding column is introduced into an ion-exchange resin and/or a non-ionic adsorption resin column. Moreover, it relates to the DHPG extract obtainable by means of the process disclosed and to the applications thereof. | 2012-02-23 |
20120046369 | Methods for enhancing the stability of foods, beverages, and cosmetics using natural products derived from non-allergenic proteinaceous sources - The present invention relates to compositions with effective metal chelating activity and utility as natural antioxidants in food, beverages, nutritional supplements and cosmetics. The compositions of the present invention may be prepared by enzymatically hydrolyzing hypoallergenic protein isolates derived from vegetables, for example yellow pea ( | 2012-02-23 |
20120046370 | PROCESS FOR PRODUCING A PURIFIED SYNTHESIS GAS STREAM - A process for producing a purified synthesis gas stream from a feed synthesis gas stream comprising besides the main constituents carbon monoxide and hydrogen also hydrogen sulphide, HCN and/or COS, the process comprising the steps of: (a) contacting one part of the feed synthesis gas stream with a water gas shift catalyst in a shift reactor in the presence of water and/or steam to react at least part of the carbon monoxide to hydrogen and carbon dioxide, to obtain a shifted synthesis gas stream enriched in hydrogen and in carbon dioxide; (b) contacting another part of the feed gas stream with a hydrolysis catalyst in the presence of water to remove HCN and/or COS to obtain a hydrolysed synthesis gas stream depleted in HCN and/or COS; (c) removing H | 2012-02-23 |
20120046371 | Low Equivalent Weight Ionomer - An ionomer and a process for forming the ionomer such that the ionomer has (1) low equivalent weight (below 950, preferably between 625 and 850, and most preferably between 675 and 800) and (2) high conductivity (greater than 0.13 S/cm). In another embodiment, the invention is an ionomer having (1) low equivalent weight (below 950, preferably between 625 and 850, and most preferably between 675 and 800) and (2) acceptably low hydration (less than about 120 weight percent). These ionomers are capable of being processed into thin film and are extremely well-suited for low humidity or high temperature fuel cell applications. | 2012-02-23 |
20120046372 | BLOWING AGENTS, FOAMABLE COMPOSITIONS AND FOAMS - A method of forming foam comprising: (a) providing at least a first relatively high pressure liquid comprising a first reactive component; (b) introducing into said relatively high pressure stream a liquid blowing agent composition comprising 1,3,3,3-tetrafluoropropene (HFO-1234ze) and/or HFCO-1233zd to produce a second stream at relatively high pressure and containing said blowing agent; and (c) mixing at least a portion of said third stream with a fourth stream containing a component reactive with said first component to produce a mixed reactive stream. | 2012-02-23 |
20120046373 | Phylon Processes of Making Foam Articles Comprising Ethylene/alpha-Olefins Block Interpolymers - Methods of making a foam article comprise the steps of compressing a foam at an elevated temperature in a mold for shaping the foam; and cooling the mold to a temperature greater than room temperature, wherein the foam comprises at least one ethylene/α-olefin block interpolymer. The foam may further comprise an ethylene vinyl acetate copolymer and an additive such as a filler or a crosslinking agent. The ethylene/α-olefin block interpolymers are a multi-block copolymer comprising at least one soft block and at least one hard block. | 2012-02-23 |
20120046374 | EXTRUDED FOAMS WITH IMPROVED STIFFNESS - The present invention relates to an extruded foam based on at least one polymer selected from polysulfone or polyether sulfone, polystyrene, or a copolymer produced from styrene, where the extruded foam comprises at least one mineral filler with a particle sizes ≦10 μm, and comprises at least one nucleating agent based on a wax or on an oligomer containing epoxy groups. | 2012-02-23 |
20120046375 | PROTECTIVE COATING FOR WINDOW GLASS - The invention is a composition comprising: a) one or more film forming resins having at least one functional group capable of polymerization; b) one or more reactive diluents capable of reacting with the film forming resin; c) one or more silicon, titanium, zirconium, aluminum or metal containing compounds capable of promoting adhesion of the composition to glass; d) one or more fillers capable of imparting abrasion resistance to the composition when cured; and e) one or more compounds which is reactive with the film forming resin which also contains at least one acidic moiety. The composition of the invention is useful as a frit on the window of a vehicle. | 2012-02-23 |
20120046376 | POLYMERIZABLE POLYMERIC PHOTOINITIATORS AND RADIATION CURABLE COMPOSITIONS - A polymerizable polymeric photoinitiator according to Formula (I): | 2012-02-23 |
20120046377 | Photoinitiators - The present invention is related to novel photoinitiators, in particular to photoinitiators comprising amino groups within the molecule. | 2012-02-23 |
20120046378 | Water-Based Digital Ink - Water-based digital inks that exhibit broad adhesion and high-elongation characteristics are provided. The inks are capable of curing by various mechanisms such as through exposure to UV light and/or catalytic reactions resulting from the evaporation of water from the ink. | 2012-02-23 |
20120046379 | METHOD OF MAKING A HARD LATEX AND A HARD LATEX - A method of making a hard latex from a latex comprising an aqueous dispersion of a polymer, the method comprising the step of exposing the latex to infrared radiation. | 2012-02-23 |
20120046380 | SYNERGISTIC EFFECTS OF BLENDING MULTIPLE ADDITIVES IN UHMWPE - Oxidation resistant crosslinked ultrahigh molecular weight polyethylene (UHMWPE) is described, wherein at least two different additives in the manufacture synergistically increase the oxidation resistance of crosslinked UHMWPE. This allows the manufacture of oxidation resistant crosslinked UHMWPE using lower levels of additives and/or lower levels of crosslinking irradiation or chemicals. The lower levels of additives and/or crosslinking produce crosslinked UHMWPE having desired physical properties not possible without the synergistic interaction of the additives. This crosslinked UHMWPE may be used in medical prostheses such as in bearing components having desired physical properties such as wear resistance and oxidation resistance not possible without the synergistic interaction of the additives. | 2012-02-23 |
20120046381 | Method For Curing Resin With Ultrasound - A method for curing a resin includes the steps of placing the resin into a reaction vessel, drawing a vacuum in the reaction vessel, positioning the reaction vessel in a gaseous coupling fluid, and applying ultrasonic energy to the coupling fluid. | 2012-02-23 |
20120046382 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS - The invention provide a new class of silicone-containing prepolymers containing dangling polysiloxane-containing polymer chains. This class of silicone-containing prepolymer is capable of being actinically crosslinked to form a silicone hydrogel material with a relatively high oxygen permeability, a reduced elastic modulus, and a relatively high ion permeability. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and to methods for making the silicone hydrogel contact lenses. | 2012-02-23 |
20120046383 | SILICONE RUBBER COMPOSITION - The silicone rubber composition disclosed here is formed a configuration in which vitamin E or a derivative thereof, or a salt of any one thereof is dispersed at least at a portion of the silicone rubber. Also disclosed is a method of manufacturing a medical apparatus that involves mixing a silicone rubber precursor with vitamin E or a derivative thereof, or a salt of any one thereof and hardening the obtained mixture, or a process of infiltrating a silicone rubber into vitamin E or a derivative thereof, or a salt of any one thereof in a liquid state. Further, the method of manufacturing a medical apparatus as disclosed here includes installing the obtained silicone rubber composition onto a medical apparatus; hermetically packaging the obtained medical apparatus; and irradiating radiation to the hermetically packaged medical apparatus. | 2012-02-23 |
20120046384 | PHOTOACTIVATABLE CROSSLINKER - Described herein is a degradable linking agent of formula Photo | 2012-02-23 |
20120046385 | BONE CEMENT COMPOSITION AND PRODUCTION METHOD THEREOF, AND KIT FOR PRODUCING THE SAME - The invention has as its objects the provision of a bone cement composition and a bone cement composition kit for obtaining the bone cement composition having bioactivity and capable of forming a hardened material having high mechanical strength practically required, and the provision of a bone cement formed material having both bioactivity and high mechanical strength practically required and a production method thereof. | 2012-02-23 |
20120046386 | Dental primer adhesive system and optional hydrophobic resin - The present application relates to a polymerizable dental primer/adhesive system comprising a primer component having a relatively hydrophilic monomer component in an amount that renders the system relatively hydrophilic before polymerization of the system and capable of penetrating a prepared dental surface such as etched tooth dentin or enamel, and a multi-functional cross-linking agent in an amount that renders the system relatively hydrophobic after polymerization. A polymerizable hydrophobic monomer component is also included in the primer. The inclusion of said hydrophobic polymerizable monomer and said multi-functional cross-linking agent improves the long term stability or durability of the polymerized primer system to the dental restoration and to the tooth, dentin, enamel and other dental surfaces. An additional hydrophobic resin can also be employed with the primer adhesive system. The dental primer adhesive system exhibits greater stability and durability over time when compared to other dental adhesive systems. | 2012-02-23 |
20120046387 | SLURRY FOR PREPARING BORON NITRIDE AGGREGATES OF SPHERICAL GEOMETRY AND APPLICATION THEREOF - The present invention provides a slurry for preparing boron nitride aggregates of spherical geometry, comprising: 3 wt %˜25 wt % of boron nitride; 1 wt %˜25 wt % of a nano-ceramic material; and a solvent as a complement to 100 wt %. In comparison with conventional preparation methods, preparation of boron nitride aggregates of spherical geometry at relatively low temperature can be achieved by using the slurry. Therefore, the demands of energy conservation and low cost are fulfilled. Besides, the present invention also provides a method for preparing boron nitride aggregates of spherical geometry. | 2012-02-23 |
20120046388 | Liquid Monobenzoxazine Based Resin System - The present invention provides a liquid resin system including a liquid monobenzoxazine monomer and a non-glycidyl epoxy compound, wherein the weight ratio of the monobenzoxazine monomer to the non-glycidyl epoxy compound is in a range of about 25:75 to about 60:40. The liquid resin system exhibits a low viscosity and exceptional stability over an extended period of time making its use in a variety of composite manufacturing methods highly advantageous. | 2012-02-23 |
20120046389 | High pH Process Resistant Coating For Metal Food Containers - Disclosed is an improved coating composition for food containers that is resistant to high pH processing environments. The improved coating composition is based upon an epoxy-amino resin coating composition that has been modified with other components to improve its performance in high pH environments balanced with flexibility, formability and abrasion resistance. Typically, the coating composition includes an epoxy resin, an amino resin cross-linking agent, a blocked polyisocyanate and a saturated polyester. | 2012-02-23 |
20120046390 | EPOXY RESIN COMPOSITION - An epoxy resin composition has a glass transition temperature between 20° C. and 75° C. The epoxy resin composition includes an epoxy resin, a plurality of water vapor-proof particles, and at least two kinds of amino-functional curing agents. One of the amino-functional curing agents is a polyamine-type curing agent. The weight percent of the curing agent corresponding to the epoxy resin is between 10% and 95%. | 2012-02-23 |
20120046391 | ANISOTROPIC COMPOSITE - A thermosettable composition including: (a) at least one thermosetting resin; (b) at least one curing agent for the at least one thermosetting resin; (c) at least one high aspect ratio filler; wherein the aspect ratio of the filler is higher than 5:1; and (d) optionally, at least one catalyst for polymerization, including homopolymerization, of the at least one thermosetting resin; or optionally, at least one catalyst for a reaction between the at least one thermosetting resin and the at least one curing agent. | 2012-02-23 |
20120046392 | Dynamic Copolymers For Workability Retention of Cementitious Composition - A process for the production of high early strength cementitious compositions includes mixing hydraulic cement, aggregate, water, and a slump retention admixture, wherein the slump retention admixture is a dynamic copolymer containing residues of at least the following monomers: A) a ethylenically unsaturated dicarboxylic acid, B) an ethylenically unsaturated alkenyl ether having an C | 2012-02-23 |
20120046393 | Nano-hybrid Concrete Chemical Admixture for Chloride Invasion Resistance Consisting of Layered Double Hydroxide/Polyurethane Copolymer - The present invention relates to a chloride penetration resistant nano-hybrid concrete chemical admixture comprising layered double hydroxide and polyurethane copolymer. More specifically, nano-hybrid concrete chemical admixture obtained by combining the two compounds at a nano-scale, the layered double hydroxide which exhibits resistance to chloride penetration, and polyurethane copolymer which entails an excellent water reducing ability, durability and workability. In addition, the inorganic/organic hybrid material described herein exhibits high water reducing ability, improved resistance to chloride penetration, and thus can be used as chloride penetration resistant concrete chemical admixture for marine concretes. | 2012-02-23 |
20120046394 | HEMP FIBER REINFORCED COMPOSITE WITH RECYCLED HIGH DENSITY POLYETHYLENE AND PRODUCTION THEREOF - Novel structural materials composed of industrial hemp fiber with recycled high density polyethylene (HDPE) as well as methods for the production of the same are disclosed. The material's mechanical strength outperforms that of conventional lumber and could compete with glass fiber reinforced composites, particularly in tensile strength. In addition, this material offers many other significant advantages including insect free, high moisture resistance, no harmful chemical treatments, and no rapid corrosion in water environments. | 2012-02-23 |
20120046395 | SUPRAMOLECULAR POLYMER-CONTAINING BITUMINOUS COMPOSITION - The present invention relates to a bituminous composition comprising at least one bitumen and at least one polycondensate capable of forming a supramolecular assembly comprising one or more associative group(s) The present invention also relates to the use of such bituminous composition for the preparation of asphalt mixtures useful for the coating of rolling surfaces, for the preparation of water-proofing coatings, and the for the preparation of adhesive formulations. | 2012-02-23 |
20120046396 | SUPERTRANSPARENT HIGH IMPACT STRENGTH RANDOM BLOCK COPOLYMER - A high impact strength random block copolymer including (a) about 65-97 wt. % of a crystalline propylene/ethylene copolymer A containing from about 0.5 wt. % to about 6 wt. % derived from ethylene and from about 94 wt. % to about 99.5 wt. % derived from propylene, and (b) about 3-35 wt. % of a propylene/ethylene copolymer B containing from about 8 wt. % to about 40 wt % derived from ethylene and from about 60 wt % to about 92 wt. % derived from propylene. The crystalline to amorphous ratio Lc/La of the random block copolymer ranges from about 1.00 to about 2.25. The random block copolymer is characterized by both high toughness and low haze. | 2012-02-23 |
20120046397 | METHOD FOR PRODUCING PHOSPHONIC ACID METAL SALT FINE PARTICLES - There is provided to a method for efficiently producing phosphonic acid metal salt fine particles with an average particle diameter of 0.5 μm or less with high efficiency. A method for producing phosphonic acid metal salt fine particles, comprising: a) causing a reaction of a phosphonic acid compound of Formula (I): | 2012-02-23 |
20120046398 | SALT RESISTANT POLYAMIDE COMPOSITIONS - Disclosed is a thermoplastic composition including: | 2012-02-23 |
20120046399 | NANOCOMPOSITE BLENDS WITH POLYESTERS - Thermoplastic molding compositions comprising
| 2012-02-23 |
20120046400 | POLYPROPYLENE RESIN SUITABLE FOR SOFT NONWOVEN APPLICATIONS - A polypropylene impact copolymer is disclosed. The propylene impact copolymer composition comprises from 60 to 90 percent by weight of the impact copolymer composition of a matrix phase, which can be a homopolymer polypropylene or random polypropylene copolymer having from 0.1 to 7 mol percent of units derived from ethylene or C | 2012-02-23 |
20120046401 | METHOD FOR THE REDUCTION OF POLAR ADDITIVES REQUIRED FOR USE IN POLYOLEFINS - A method for improving the efficacy of polar additives used in polyolefins is disclosed. The method is related to the addition of an effective amount of a co-additive compound of the formula R | 2012-02-23 |
20120046402 | POLY LACTIC ACID-CONTAINING FILM OR SHEET, AND METHOD FOR MANUFACTURING THEREOF - Provided are a film or sheet composed of a resin composition that includes a poly lactic acid (A), an acidic functional group-modified olefinic polymer (B) including an acidic functional group and having an acid value of 10 to 70 mg KOH/g and a weight average molecular weight of 10,000 to 80,000, a tetrafluoroethylene polymer (C), and a dicarboxylic acid ester-containing plasticizer (D) containing a compound of General Formula (1) and in which the dicarboxylic acid ester-containing plasticizer (D) is included in an amount of 8 parts by weight or more and less than 40 parts by weight based on 100 parts by weight of the poly lactic acid (A), and a method for manufacturing the film or sheet by melt film formation. Each sign in Formula is as described in the specification. | 2012-02-23 |
20120046403 | AQUEOUS MID-COAT PAINT COMPOSITION - Disclosed is an aqueous mid-coat paint composition comprising a water-soluble or water-dispersible polyester resin (A) having from 2 to 10 mass % of polyethylene glycol groups or polyethylene glycol ether groups of number average molecular weight from 300 to 600; carboxylic acid secondary or tertiary amine salt groups obtained by neutralizing carboxylic acid groups; a total number of from 0.8 to 1.2 of said polyethylene glycol groups or polyethylene glycol ether groups and said carboxylic acid secondary or tertiary amine salt groups per number average molecular weight of the resin; and (B) a melamine resin as curing agent, wherein the ratio by mass of the resin solid fractions of the (A) component and the (B) component is from 75/25 to 90/10. | 2012-02-23 |
20120046404 | PAPER COATINGS OF AMPHIPHILIC, NON-WATER-SOLUBLE COMB-BRANCHED (METH)ACRYLIC POLYMERS, USES THEREOF - Polymers, paper coating compositions, and coated paper. | 2012-02-23 |
20120046405 | BARRIER COATINGS STABILIZED WITH MULTI-VALENT METAL CATIONS - A method of making a composite barrier coating composition comprising: (a) providing a first aqueous dispersion comprising a dispersed, anionically functionalized matrix resin; (b) providing a second aqueous dispersion comprising a dispersed platy mineral filler; the first and second dispersions optionally including one or more additives selected from the group consisting surfactants, emulsifiers, anti-foaming agents, dispersing agents, wetting agents, leveling agents and thickeners; (c) adding a multi-valent metal cation crosslinking agent to at least one of said first and second aqueous dispersions; and (d) admixing the first and second aqueous dispersions to form the composite wherein the composite forms a stable aqueous emulsion and the multi-valent metal cation is operative to stabilize a film formed from the composite against gas barrier performance loss at elevated levels of relative humidity. | 2012-02-23 |
20120046406 | Process for the Production of Polyolefins with Broad Molecular Weight Distribution - The present invention is directed to a propylene homo- or copolymer having
| 2012-02-23 |
20120046407 | METHOD OF PREPARING STIMULUS-RESPONSIVE POLYMERIC PARTICLES - A method of making a polymeric compound, comprising discrete particles responsive to an external stimulus, that is resistant to aggregation in high-shear fields, which includes the addition of a polymerization initiator to a reaction mixture comprising a monomer corresponding to the polymeric compound, wherein the method comprises the portion-wise addition of aliquots of a cross-linking agent to the reaction mixture, wherein an aliquot of the cross-linking agent is added to the reaction mixture both before the addition of the polymerization initiator and after the polymerization has progressed substantially to completion. The polymer particles are largely immune to the effects of transient shear rates at least as high as 10 | 2012-02-23 |
20120046408 | Stabilized acrylonitrile/acrylate molding compositions - The present invention relates to a thermoplastic molding composition containing:
| 2012-02-23 |
20120046409 | HYBRID DISPERSIONS AND METHODS FOR PRODUCING THE SAME - The instant invention is a hybrid dispersion, method of producing the same, articles made therefrom, and method of making such articles. The hybrid dispersion according to the present invention comprises the blending product of: (a) less than 30 percent by weight of a minor component comprising a hydrophobic polyurethane dispersion derived from one or more natural oil based polyols, based on the weight of the hybrid dispersion; and (b) less than 100 percent by weight of a major component selected from the group consisting of a latex emulsion, an epoxy, and a polyolefin dispersion; wherein the hybrid dispersion has a solid content in the range of 10 to 75 percent based on the weight of the hybrid dispersion. | 2012-02-23 |
20120046410 | TREAD COMPOSITIONS WITH IMPROVED DYNAMIC STORAGE MODULUS - A process for forming a tire component, the process comprising the steps of introducing a vulcanizable polymer, a curative, a first carbon black characterized by an iodine adsorption number, per ASTM D1510, that is greater than 60 g/kg, and a second carbon black characterized by an iodine adsorption number, per ASTM D1510, that is less than 60 g/kg to form a vulcanizable composition, fabricating a tire component from the vulcanizable composition, and curing the tire component. | 2012-02-23 |
20120046411 | Recycled Resin Compositions And Disposable Medical Devices Made Therefrom - Compositions including recycled resin components and medical devices and components made from such compositions are disclosed. The compositions and medical devices are characterized as biocompatible and sterilization stable. In one or more embodiments, the compositions include a recycled resin component and may include one or more of an anti-oxidant component, slip additive component, anti-static component, impact modifier component, colorant component, acid scavenger component, X-ray fluorescence agent component, radio opaque filler component, surface modifier component, melt stabilizer component, clarifier component, processing aid component and reinforcing agent component. Methods of forming medical articles and components are also disclosed. | 2012-02-23 |
20120046412 | AMPHIPHILIC AND NON-WATER SOLUBLE (METH)ACRYLIC COMB POLYMERS - Non water-soluble polymers with a comb structure and a (meth)acrylic skeleton on which are grafted side chains containing at least one hydrophobic monomer of the styrene or (meth)acrylic ester type on C1 to C4, and at least one hydroxy or methoxy polylakylene glycol monomer. The levels of monomers are such that the polymer is amphiphilic because it is both rich in hydrophobic monomer and polylakylene glycol monomer. These products, used in paper coating dispersions, enable an increase in their Brookfield™ viscosity, a reduction in their ACAV viscosity, and an improvement in their water retention, which makes them particularly well suited for dry extract and/or high deposit speed coatings. | 2012-02-23 |
20120046413 | PNEUMATIC TIRE - A pneumatic tire obtained by using a rubber composition containing 100 parts by mass of a rubber component comprising at least one of natural rubber and diene base synthetic rubber, 20 to 150 parts by mass of precipitated silica as a filler in which a cetyltrimethylammonium bromide-adsorbing specific surface area (CTAB) (m | 2012-02-23 |
20120046414 | METHOD FOR PRODUCING SOLID POLYGLYCOLIC ACID-BASED RESIN COMPOSITION - A method for producing a solid polyglycolic acid-based resin composition, including a cooling step of cooling a polyglycolic acid-based resin composition in a molten state by an aqueous medium, wherein in the cooling step, the polyglycolic acid-based resin composition in the molten state is cooled by being brought into contact with the aqueous medium so that a sodium ion concentration in an obtained solid polyglycolic acid-based resin composition can be less than 100 ppb by mass. | 2012-02-23 |
20120046415 | METHODS OF FORMING BLOCK COPOLYMERS, METHODS OF FORMING A SELF-ASSEMBLED BLOCK COPOLYMER STRUCTURE AND RELATED COMPOSITIONS - Methods of modifying block copolymers to enhance thermodynamic properties thereof without sacrificing material properties and methods of forming modified block copolymers having desired properties are disclosed. The modified block copolymers may be used, for example, as a mask for sublithographic patterning during various stages of semiconductor device fabrication. For example, block copolymers having desirable material properties, such as etch selectively, may be chemically modified to tailor a χ value thereof to optimize the process conditions for achieving a self-assembled state and to reduce a defectivity of the self-assembled block copolymer pattern. | 2012-02-23 |
20120046416 | IMPACT ADDITIVES - The invention relates to a polymer of core-shell structure containing a core having at least one elastomeric polymer, with a glass transition temperature of less than 25° C., and a shell having at least one polymer, with a glass transition temperature of greater than 25° C., where at least one of the polymers includes (meth)acrylic acid ester monomers containing organic carbon derived from biomass. The present invention also relates to a process for preparing the core-shell polymers and to their use as impact additives, and to a composition containing them. | 2012-02-23 |
20120046417 | Propylene Polymer Compositions - A propylene composition comprising (percent by weight):
| 2012-02-23 |
20120046418 | CROSSLINKABLE POLYMER MATERIAL, CROSSLINKED POLYMER MATERIAL, AND PRODUCTION METHOD THEREOF - The present invention provides a production method of a crosslinkable polymer material which includes adding 2-(glycidyloxy)-1-naphthonitrile oxide or 2-[5-(ethoxycarbonyl)pentyloxy]-1-naphthonitrile oxide by an addition reaction to a polymer material having a multiple bond to which a nitrile oxide is added by an addition reaction so as to introduce a glycidyl group or an ethoxycarbonyl group into the polymer material. | 2012-02-23 |
20120046419 | METHODS AND MATERIALS FOR HYDROCARBON RECOVERY - Crosslinked polyolefins for use in recovering or containing hydrocarbons such as hydrocarbons contained in oil, are disclosed. Advantageously, the crosslinked polyolefins absorb the hydrocarbon to form a gel that can be collected and processed by heat to release the collected hydrocarbons. | 2012-02-23 |
20120046420 | POLYMER, METHOD FOR PRODUCING POLYMER, RESIN COMPOSITION FOR OPTICAL MATERIAL, SHAPED ARTICLE, OPTICAL MATERIAL, AND LENS - A polymer containing a recurring unit having an aliphatic polycyclic structure, wherein at least two atoms constituting the ring skeleton of the aliphatic polycyclic structure constitute the main chain of the polymer, and the recurring unit has an aliphatic ring containing a sulfonyl group as the constitutive group of the ring skeleton, has high refractivity, high Abbe's number, high-level heat resistance, high-level light transmittance and low water absorption. | 2012-02-23 |
20120046421 | Ordered Nanoscale Domains by Infiltration of Block Copolymers - A method of preparing tunable inorganic patterned nanofeatures by infiltration of a block copolymer scaffold having a plurality of self-assembled periodic polymer microdomains. The method may be used sequential infiltration synthesis (SIS), related to atomic layer deposition (ALD). The method includes selecting a metal precursor that is configured to selectively react with the copolymer unit defining the microdomain but is substantially non-reactive with another polymer unit of the copolymer. A tunable inorganic features is selectively formed on the microdomain to form a hybrid organic/inorganic composite material of the metal precursor and a co-reactant. The organic component may be optionally removed to obtain an inorganic feature s with patterned nanostructures defined by the configuration of the microdomain. | 2012-02-23 |
20120046422 | Multi-Arm Block Copolymers as Drug Delivery Vehicles - The invention provides methods for making copolymers and multi-arm block copolymers useful as drug delivery vehicles. The multi-arm block copolymers comprise a central core molecule, such as a residue of a polyol, and at least three copolymer arms covalently attached to the central core molecule, each copolymer arm comprising an inner hydrophobic polymer segment covalently attached to the central core molecule and an outer hydrophilic polymer segment covalently attached to the hydrophobic polymer segment, wherein the central core molecule and the hydrophobic polymer segment define a hydrophobic core region. The solubility of hydrophobic biologically active agents can be improved by entrapment within the hydrophobic core region of the block copolymer. The invention further includes pharmaceutical compositions including such block copolymers, pharmaceutical compositions, and methods of using the block copolymers as drug delivery vehicles. | 2012-02-23 |
20120046423 | POLYORGANOSILOXANE, ENCAPSULATION MATERIAL OBTAINED FROM THE POLYORGANOSILOXANE, AND ELECTRONIC DEVICE INCLUDING THE ENCAPSULATION MATERIAL - A polyorganosiloxane composition, an encapsulation material, and an electronic device, the polyorganosiloxane composition including a linear first polyorganosiloxane resin including a moiety represented by the following Chemical Formula 1 and a moiety represented by the following Chemical Formula 2, the first polyorganosiloxane resin including double bonds at both terminal ends thereof, and a second polyorganosiloxane resin having a three dimensional network structure, | 2012-02-23 |
20120046424 | NOVEL COMPOSITIONS AND METHODS TO PRODUCE TRIAZINE-ARYLHYDROXY-ALDEHYDE CONDENSATES WITH IMPROVED SOLUBILITY - Compositions and methods for forming condensates and resin compositions are provided. In one embodiment, a condensate is formed from a reaction mixture including a triazine monomer, an arylhydroxy monomer, an aldehyde monomer and an acid catalyst having a pKa value of greater than 3.8. The condensates contain up to 28 wt. % of nitrogen and have a melt viscosity of 3,000 cps or less at 175° C. The condensates may have a solubility of at least 80 wt. % solids dissolved in an organic solvent for 120 hours or greater. Also disclosed are methods for the manufacture of the condensate as well as the condensate's use in fire-retardant epoxy resin compositions suitable for the manufacture of laminates for electronic applications. There is also disclosed a glycidylated triazine-arylhydroxy-aldehyde condensate of this invention. | 2012-02-23 |
20120046425 | POLYMERIC GLYCIDYL ETHERS REACTIVE DILUENTS - A thermosettable resin composition including (a) at least one thermosetting resin; (b) at least one polymeric glycidyl reactive diluent; and (c) a hardener; a process for producing the thermosettable resin composition; a cured product comprising the cured thermosettable composition; and a process for producing the cured resin thermoset product including (I) admixing (a) at least one thermosetting resin; (b) at least one polymeric glycidyl reactive diluent; and (c) a hardener; and (II) curing the mixture of step (I). | 2012-02-23 |
20120046426 | OLEFIN POLYMERIZATION PROCESS WITH REDUCED FOULING - The invention concerns methods for polymerization of olefins comprising contacting one or more monomers selected from ethylene and α-olefins with a supported single site catalyst in the presence of one or more magnesium alkyl compounds wherein said magnesium alkyl is present during the major portion of said polymerization. | 2012-02-23 |
20120046427 | "GREEN" PLASTIC MATERIALS AND METHODS OF MANUFACTURING THE SAME - A process is disclosed for producing plastic materials by providing a biology based feedstock and reacting the biology based feedstock to form a feedstock capable of reaction to form the plastic material, wherein the plastic material is selected from polystyrene and polyethylene terephthalate (PET). | 2012-02-23 |
20120046428 | Mixed Metal Catalyst Systems Having a Tailored Hydrogen Response - A polymerization catalyst system and polymerization processes using the catalyst systems are disclosed. The polymerization catalyst systems may include a) a first catalyst compound, and b) a second catalyst compound, wherein the first catalyst compound includes an oxadiazole-containing compound. In some embodiments, the oxadiazole-containing compound has essentially no hydrogen response, thus allowing better and/or tailored control of product properties when producing polymers using the catalyst system. | 2012-02-23 |
20120046429 | Sequential Formation of Ziegler-Natta Catalyst Using Non-blended Components - Catalyst compositions, methods of forming the same and polymers formed therefrom are described herein. The methods of forming the catalysts generally include contacting an alkyl magnesium compound with a viscosity modifier prior to contact with an alcohol to form a magnesium dialkoxide compound; contacting the magnesium dialkoxide compound with a first titanium alkoxide and a first agent to form a first solution reaction product “A”, wherein the titanium alkoxide and the first agent are non-blended individual components prior to contacting the magnesium dialkoxide; contacting the first solution reaction product “A” with a second titanium alkoxide to form a second solution reaction product “B”; contacting the second solution reaction product “B” with a second agent to form a first solid reaction product “C”; contacting the first solid reaction product “C” with a third agent to form a second solid reaction product “D”; and contacting the second solid reaction product “D” with a reducing agent to limn a catalyst component. | 2012-02-23 |
20120046430 | Transportable and Safely Packaged Organic Peroxide Formulations - The present invention relate to a packaged peroxide formulation which comprises a container and a liquid peroxide formulation, wherein: said container has a volume of at least 50 litres, said liquid peroxide formulation comprises (i) 51 to 59 wt % of an organic peroxides selected from the group consisting of peroxyesters, their derivatives, and mixtures thereof, and (ii) optionally an additive selected from the group consisting of a phlegmatiser. The invention also relates to a method to safely produce, handle and transport a packaged organic peroxide formulations as defined above. | 2012-02-23 |
20120046431 | STIMULUS-RESPONSIVE COMPOUND, ACTUATOR, AND STIMULUS-RESPONSIVE COMPOUND PRODUCING PROCESS - A stimulus-responsive compound includes a pair of alkyl chains; a crosslinking portion that crosslinks the pair of alkyl chains; and a liquid-crystalline functional group attached to at least one of the alkyl chains. The crosslinking portion includes: a unit A that has a bond that serves as a rotational axis, a first group positioned at one end of the bond, and a second group positioned at the other end of the bond, a first unit B disposed at a first bonding site of the first group, and a second unit B disposed at a first bonding site of the second group. The first unit B and the second unit B are capable of forming a bond between each other through redox reaction. | 2012-02-23 |
20120046432 | PROCESS FOR PRODUCING (METH)ACRYLIC ACID AND CRYSTALLIZATION SYSTEM - A process for producing (meth)acrylic acid comprising the steps of: supplying a cooling medium to a crystallizer ( | 2012-02-23 |