08th week of 2010 patent applcation highlights part 43 |
Patent application number | Title | Published |
20100047316 | REPAIR OF CARTILAGE TISSUE USING A MATRIX GEL CONTAINING CHONDROCYTES - The present invention relates in one aspect to the use of a matrix gel comprising chondrocytes or progenitor cells thereof in a density below that of natural cartilage as a cartilage repair implant wherein said cells exhibit increases production of extracellular matrix material. | 2010-02-25 |
20100047317 | USING BUCKY PAPER AS A THERAPEUTIC AID IN MEDICAL APPLICATIONS - Methods, systems, and uses of bucky paper are provided in the present invention. These embodiments include covering medical implants with single or multiple layers of bucky paper, treating bucky paper with various therapeutics to be released through the bucky paper to a target site, shaping bucky paper into non-conventional configurations for improved therapeutic deliver, and using bucky paper alone or in conjunction with other materials to treat a target site. | 2010-02-25 |
20100047318 | CERAMIC IMPLANTS AFFORDING CONTROLLED RELEASE OF ACTIVE MATERIALS - Implantable compositions capable of providing release of bioactive agents according to a predetermined release profile and methods for their use. Such compositions include at least one ceramic substrate; a bioactive substance loaded on a surface of a said ceramic substrate forming a loaded surface zone operable to release said bioactive substance according to a release profile under physiological conditions; and a biodegradable polymer having an in vivo degradation period, forming a continuous or discontinuous coating on an area of a said ceramic substrate. The composition comprises at least two said loaded surface zones having different release profiles, or at least two said coatings having different in vivo degradation periods. | 2010-02-25 |
20100047319 | Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times - This invention is generally related to coating layers for implantable medical devices, such as drug delivery vascular stents, and methods of fabricating coated implantable medical devices. Specifically various embodiments of the present invention include methods of fabricating and modulating of coating layers to enhance bioabsorption. The coating layers include poly(ester-amide) and/or poly(amide) polymers. | 2010-02-25 |
20100047320 | ORAL POLYMERIC MEMBRANE FERULOYL ESTERASE PRODUCING BACTERIA FORMULATION - The present invention relates to an oral formulation to lower serum or hepatic lipid and triglyceride concentrations, hepatic inflammation and/or insulin resistance in a patient comprising live feruloyl esterase producing microorganisms alone or in association with a pharmaceutically acceptable carrier resistant to gastric conditions, and wherein the microorganisms are wild type, genetically modified, or combination thereof. The present invention is also directed to an oral formulation to lower serum or hepatic lipid and triglyceride concentrations, hepatic inflammation and/or insulin resistance in a patient, which comprises polymeric microcapsules containing live feruloyl esterase producing microorganisms in suspension in a pharmaceutically acceptable carrier, wherein said microcapsules are semipermeable and resistant to gastro-intestinal conditions, and wherein said microorganism are wild type, genetically modified, or combination thereof as well as methods of preventing or improving liver diseases and disorders and uses thereof. | 2010-02-25 |
20100047321 | SILVER ANTIMICROBIAL COMPOSITION AND USE - Aqueous silver-containing composition is designed for use as an antimicrobial agent on fibers and fabrics. This composition includes silver halide particles, gelatin, and an additive that includes an N-heterocyclic acid having a pKa of from about 4 to about 9. The additive improves the redispersibility and shelf-life of the composition. | 2010-02-25 |
20100047322 | Combination antihypertensive wafer - Sheet-like dosage forms that quickly dissolve or disintegrate in an aqueous environment, for the application of active agent combinations for the treatment of hypertension. The dosage forms contain at least two active agents that are suitable for the treatment of hypertension. The antihypertensive agents are selected from the group that encompasses beta receptor blockers, alpha receptor blockers, calcium antagonists, ACE inhibitors, AT | 2010-02-25 |
20100047323 | CHITOSAN SOLUTION AND MEDICAL PREPARATION WITH CHITOSAN COATING FORMED FROM THE SOLUTION - A chitosan coating solution safe for oral administration, a water resistant chitosan coating film with reduced content of residual organic acid, and a coated medical preparation having the coating film are described. The preparation method includes incorporating a glycerin fatty acid ester into an aqueous chitosan solution prepared through dissolution with a volatile organic acid. The chitosan coating film is obtained by drying and solidifying the solution through film coating. The organic acid used in the dissolution remains in the coating film only minutely and the film is water resistant. When the chitosan coating solution (containing a glycerin fatty acid ester, and prepared through dissolution with a volatile organic acid) is coated, a film is formed therewith, and the organic acid volatilizes simultaneously, producing a chitosan water resistant coating film. Forming a known enteric coating film in combination with the outer coating film allows application to large-intestine drug delivery. | 2010-02-25 |
20100047324 | Multi-Functional Wound Dressing Matrices and Related Methods - Various embodiments are directed to multi-functional wound-care dressing matrices that can protect and promote new tissue growth at a wound site. The multi-functional wound care matrix can incorporate polyphosphazenes of formula I, as a component that can be configured into various forms, including as fibrous mats, porous membranes, nonporous films, particulate formulations, and equivalents. The multi-functional wound-care dressing matrix of the present disclosure exhibit high-performance properties conferred by polyphosphazenes of formula I. Exceptional biocompatible properties of polyphosphazenes of formula I provide an ideal tissue-contacting surface for the multi-functional wound-care dressing matrix of interest. | 2010-02-25 |
20100047325 | ANALGESIC ANTI-INFLAMMATORY PATCHES FOR TOPICAL USE - The invention provides an analgesic anti-inflammatory patch of a hydrophobic type for topical application containing, in a Pressure Sensitive Adhesive(PSA), diclofenac sodium, pyrrolidone or a derivative thereof, a polyhydric alcohol fatty acid ester, and an organic acid. The patch exerts the following effects: | 2010-02-25 |
20100047326 | Multiple-Compartment Applicator - A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient. | 2010-02-25 |
20100047327 | Adjuvant for Transdermal or Transmucosal Administration and Pharmaceutical Preparation Containing the Same - It is intended to provide a low molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for enhancing immunogenicity of an antigen efficiently. It can be achieved by an immunostimulant adjuvant containing at least one substance selected from the group consisting of aliphatic alcohols, free fatty acids and fatty acid derivatives but does not contain a substance represented by the following formula. | 2010-02-25 |
20100047328 | Adhesive preparation - An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein
| 2010-02-25 |
20100047329 | Novel Vaccination Carrier - An object of the present invention is to prepare novel vaccine carriers that can be used to produce vaccines that are capable of efficient induction of humoral and cellular immune responses. Another object of the present invention is to provide vaccines that are capable of efficient induction of humoral and cellular immune responses. | 2010-02-25 |
20100047330 | TREATMENT FOR DARK ADAPTATION - The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide. | 2010-02-25 |
20100047331 | METHOD OF INDUCING NEUTRALIZING ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS - The present invention relates, in general, to human immunodeficiency virus (HIV), and, in particular, to a method of inducing neutralizing antibodies to HIV and to compounds and compositions suitable for use in such a method. | 2010-02-25 |
20100047332 | Treatments for burns using thyroid hormone compound in a human - A topical preparation for treating first and second degree burns includes TriAc. The topical preparation preferably includes less than 10 mg of TriAc per 100 ml of pharmaceutical excipient base. In another embodiment, a topical preparation includes TriAc for decreasing cellulite. In this embodiment, the topical preparation is preferably applied only before exercise. In a preferred embodiment, the preparation is applied only intermittently, preferably no more than three times a week, or in amounts sufficient to not downregulate receptor number and become inefficacious. | 2010-02-25 |
20100047333 | Modified Peptides and Their Use for the Treatment of Autoimmune Diseases - Disclosed herein are a modified peptide, compositions containing the same and their use in the treatment of autoimmune diseases. The modified peptide is provided by a chemical modification of at least one of the several amino acid residues comprising the peptide. The modification is carried out by phosphorylation, acetylation or methylation, or as a combination thereof. | 2010-02-25 |
20100047334 | PH SENSITIVE LIPOSOME COMPOSITIONS FOR CONTROLLING SURFACE TOPOGRAPHY AND BINDING REACTIVITY IN FUNCTIONALIZED LIPOSOMES - Methods for controlling surface topography and binding reactivity in functionalized lipid layers, including in the form of liposomes, using pH-dependent processes. During direct cell-to-cell communication, lipids on the extracellular side of plasma membranes reorganize, and membrane associated communication-related molecules co-localize. At co-localization sites, sometimes identified as rafts, the local cell surface topography and reactivity are altered. Integration of these processes on nanometer-sized lipid vesicles used as drug delivery carriers would precisely control their interactions with diseased cells minimizing toxicities. Included are pH-dependent processes on functionalized lipid bilayers demonstrating reversible sharp changes in binding reactivity within a narrow pH window. Cholesterol enables tuning of the membrane reorganization to occur at pH values not necessarily close to the reported pKa's of the constituent titratable lipids. One illustrative function of the invention is to use liposomes to deliver bioactive agents to cancer or tumor cells and compositions of specific lipids that form liposomes to deliver a biologically active agent. | 2010-02-25 |
20100047335 | MICROVESICLES DERIVED FROM RECOMBINANT YEAST HAVING HAEMOSTATIC ACTIVITIES AND USES THEREOF - Tissue factor-bearing yeast derived microvesicles comprising a yeast membrane and a tissue factor protein, or a fragment thereof, or a tissue factor protein or a fragment thereof fused to another peptide as a fusion protein having pro-coagulant activity are disclosed. Said products can be used as pro-coagulant agents in the treatment of hemorrhages in a subject. | 2010-02-25 |
20100047336 | INHIBITION OF BRAIN ENZYMES INVOLVED IN CEREBRAL AMYLOID ANGIOPATHY AND MACULAR DEGENERATION - A method of treating or inhibiting progress of dementia and/or macular degeneration in a mammal involves administering compositions containing siRNA to heme oxygenase-1 (HO-1) or heme oxygenase-2 (HO-2), a matrix metalloproteinase (MMP) inhibitor, a caspase inhibitor, or a metalloporphyrin in a manner that permits access to brain sites and/or the macula of the patient. | 2010-02-25 |
20100047337 | PHARMACEUTICAL SPHEROIDS - According to the invention glyceryl monostearate and a polymeric binder are employed as a spheronising aid in the manufacture of pharmaceutical spheroids containing no or substantially no microcrystalline cellulose. The spheroids can contain one or more therapeutically active agent which undergoes no or substantially no degradation when stored under accelerated temperature and humidity conditions. A coating may be applied to the spheroids; when present, the coating is preferably a controlled release coating. | 2010-02-25 |
20100047338 | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity - Described are steroidal C-17 benzoazoles, pyrimidinoazoles (azabenzoazoles) and diazines. Methods for their synthesis are also described, which include methods having a step of nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene or analogs thereof and benzoazole or pyrimidinoazole nucleophiles and methods having a palladium catalyzed cross-coupling reaction of 17-iodoandrosta-5,16-dien-3β-ol or analogs thereof with tributylstannyl diazines. The compounds are potent inhibitors of human CYP17 enzyme as well as potent antagonists of both wild type and mutant androgen receptors (AR). The compounds are useful for the treatment of human prostate cancer. | 2010-02-25 |
20100047339 | COMPOSITIONS FOR THE TREATMENT OF CHRONIC DEGENERATIVE INFLAMMATORY CONDITIONS - Compositions comprising:
| 2010-02-25 |
20100047340 | HOT-MELT EXTRUSION OF MODIFIED RELEASE MULTI-PARTICULATES - The present invention includes compositions and methods of making a modified release pharmaceutical formulation and a method of preparation for the embedding of modified release multi-particulates into a polymeric or wax-like matrix. The modified release multi-particulates comprise an effective amount of a therapeutic compound having a known or desired drug-release profile. Modified release multi-particulates may include a polymeric coat or may be incorporated into particle or core material. The polymer matrix comprises a thermoplastic polymer or lipophilic carrier or a mixture thereof that softens or melts at elevated temperature and allows the distribution of the modified release multi-particulates in the polymer matrix during thermal processing. Formulation compounds and processing conditions are selected in a manner to preserve the controlled release characteristics and/or drug-protective properties of the original modified release multi-particulates. | 2010-02-25 |
20100047341 | COMBINED PREPARATION FOR THE TREATMENT OF CARDIOVASCULAR DISEASES BASED ON CHRONOTHERAPY THEORY - The present invention relates to a functional combination preparation comprising a dihydropyridine-based calcium channel blocker such as amlodipine and an ARB (Angiotensin-2 receptor blocker) such as losartan. In particular, the present invention relates to a chronotherapeutical combination pharmaceutical formulations with controlled-release for the prevention or treatment of cardiovascular disease, which is formulated in accordance with xenobiotics and chronotherapy for enabling the two drugs to be chronotherapeutically released, thereby improving the therapeutic activity as compared to the co-administration of each drug in the form of a single pill, while reducing side effects and maintaining the therapeutic activity as high as possible at the time of day when the risk of a complication of cardiovascular disease is highest. | 2010-02-25 |
20100047342 | Method and Composition for Administering an NMDA Receptor Antagonist to a Subject - The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject. | 2010-02-25 |
20100047343 | MULTIPARTICULATE FORMULATION HAVING TRAMADOL IN IMMEDIATE AND CONTROLLED RELEASE FORM - A multi-particulate pharmaceutical composition of rapid release particles and controlled release particles comprising tramadol or a salt thereof is provided. The composition provides a rapid and controlled release of tramadol or a salt thereof in a substantially pH independent manner after oral administration to a subject. The composition can be included in a capsule, caplet, sachet, or other solid dosage form adapted to retain and then release solid pharmaceutical compositions. | 2010-02-25 |
20100047344 | PERFORMANCE ENHANCING COMPOSITION AND USE THEREOF - The performance of a mammal, manifested as a reduced oxygen uptake (VO | 2010-02-25 |
20100047345 | HYDROPHOBIC ABUSE DETERRENT DELIVERY SYSTEM FOR HYDROMORPHONE - Disclosed herein are oral dosage forms of hydromorphone that are resistant to abuse and methods of their formulation. In particular, oral dosage forms that are resistant to dissolution in aqueous solutions of ethanol are described. | 2010-02-25 |
20100047346 | 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-y- lidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis-(monoethanolamine) - Disclosed are novel pharmaceutical compositions containing 3′-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid bis-(monoethanolamine) (eltrombopag olamine) and processes for preparing the same. | 2010-02-25 |
20100047347 | 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-y- lidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis-(monoethanolamine) - Disclosed are novel pharmaceutical compositions containing 3′-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid bis-(monoethanolamine) (eltrombopag olamine) and processes for preparing the same. | 2010-02-25 |
20100047348 | 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-y- lidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis-(monoethanolamine) - Disclosed are novel pharmaceutical compositions containing 3′-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid bis-(monoethanolamine) (eltrombopag olamine) and processes for preparing the same. | 2010-02-25 |
20100047349 | Stabilized solid preparation - A stabilized solid preparation having stabilized drug content and stabilized appearance, comprising a main ingredient layer and a coating layer formed on the main ingredient layer, wherein the main ingredient layer comprises a granule or a fine particle comprising a substance capable of being unstabilized when losing water of crystallization and a water-soluble polymer and the coating layer comprises a water-soluble polymer and a sugar. | 2010-02-25 |
20100047350 | OSTEOGENIC COMPOSITIONS CONTAINING A COLORING AGENT - An osteogenic composition is provided for implantation at or near a target tissue site beneath the skin, the osteogenic composition comprising a growth factor and a coloring agent, wherein the coloring agent imparts color to the growth factor to allow the user to see the growth factor at or near the target tissue site. In some embodiments, a method is provided for accelerating bone repair, the method comprising mixing bone morphogenic protein-2 and a coloring agent to form a mixture; applying the mixture to a surface of a porous collagen matrix, wherein the coloring agent allows the user to see bone morphogenic protein-2 distribution on or in the porous collagen matrix; and implanting the porous collagen matrix at or near a target tissue site in need of bone repair. | 2010-02-25 |
20100047351 | TREATMENT OF STROKE USING ISOLATED PLACENTAL CELLS - Provided herein are methods for the treatment of stroke comprising administering to a stroke victim placental stem cells, populations of cells comprising placental stem cells, and/or compositions comprising placental stem cells. | 2010-02-25 |
20100047352 | COMPOSITIONS AND METHODS FOR TREATING EXCESSIVE BLEEDING - The inventive material is a unique family of externally used wound sealants based upon a binding agent of reactive submicron silica particles that, when hydrated, agglomerate in the form of a supramolecular cross-linked network serving as the structural framework facilitating clot formation. A thrombolytic cascade accelerant can be provided, optionally with additional clotting factors, to further accelerate the clotting process. | 2010-02-25 |
20100047353 | HAIR CARE COMPOSITION - A hair care composition which comprises a plurality of cross-linked polymer particles, said polymer being the polymerization product of at least two monomer units selected from the group consisting of monoalkenyl aromatic compounds, alkyl esters derived from a saturated alcohol and acrylic or methacrylic acid, and vinyl esters of an aliphatic carboxylic acid is useful for controlling sebum on hair without providing undue whiteness to the hair. | 2010-02-25 |
20100047354 | COMBRETUM LAURIFOLIUM MART. EXTRACT AND METHODS OF EXTRACTING AND USING SUCH EXTRACT - A method of inhibiting COX-2, inhibiting NF-Kappa B activation, treating inflammation, or treating cancer may comprise administering a therapeutically effective amount of an extract of | 2010-02-25 |
20100047355 | MAGNETIC RESONANCE-DETECTABLE, ULTRASOUND-DETECTABLE AND/OR RADIOPAQUE MICROCAPSULES AND USES THEREOF - The present invention provides a microcapsule for implantation into a mammalian body, comprising: a) at least one cell and/or bioactive agent; and b) a biocompatible semi-permeable membrane encapsulating the at least one cell, wherein the biocompatible semi-permeable membrane comprises: at least one polycationic polymer region, at least one alginate polymer region, and a paramagnetic or superparamagnetic metal that does not participate in the crosslinking of the alginate polymer. The present invention further provides methods of making the microcapsules of this invention and use of the microcapsules of this invention in methods of delivering cells and/or therapeutic agents to a subject and in methods of embolization. | 2010-02-25 |
20100047356 | Charge-assembled capsules for phototherapy - Novel phototherapeutic methods and compositions are described herein. Nanoparticle-assembled microcapsules as a new type of delivery vehicle for photosensitive compounds may be synthesized through a two-step assembly process. Charged polymer chains and counterions may be combined with a photosensitive compound to form photosensitive aggregates, and then nanoparticles may be combined with the aggregates to form the microcapsules. The shell may be composed of nanoparticles and/or polymer, and the core interior may contain the photosensitive compound. Formation occurs rapidly (on the order of seconds) and the conditions are very mild (at room temperature, in aqueous solution, and at neutral pH). The microcapsule synthesis is highly suitable as an encapsulation method, particularly for a charged photosensitive molecule like ICG. | 2010-02-25 |
20100047357 | COMPOSITIONS FOR TOPICAL APPLICATION COMPRISING A PEROXIDE AND RETINOID - The invention relates to a composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient. The invention further relates to method for treating a surface condition in a subject using said composition, a method for preparing a composition exhibiting improved stability, and a kit comprising: (a) a first composition comprising a peroxide as a first active ingredient; and (b) a second composition comprising a retinoid as a second active ingredient; at least one of said first and said second active ingredient being coated by a metal oxide layer. | 2010-02-25 |
20100047358 | FOOD PROTEIN AND CHARGED EMULSIFIER INTERACTION - The present invention relates to structures obtained from protein and emulsifier interaction, more particularly to structures comprising a protein supramolecular core coated with at least a lipidic layer. The invention also encompasses methods for obtaining these structures and food compositions comprising them. | 2010-02-25 |
20100047359 | Stable powder formulation containing a novel anticholinergic agent - The invention relates to a spray-dried powder formulation comprising particles that contain the following components i) to iii): i) a compound of formula 1, in which A represents a group selected from (I), (II) or (III), R and R′ each representing hydrogen or in combination form a group selected from a single bond, —CH | 2010-02-25 |
20100047360 | Use Of Polyamines In The Treatment Of Psoriasis - The present invention provides unbranched aliphatic polyamines for use in therapy, particularly for use in the treatment of psoriasis and compositions containing polyamines. | 2010-02-25 |
20100047361 | Active Principle which is capable of inducing the conversion of inactive TGFb-Latent into active TGFb - The invention relates to active principles which are capable of inducing the conversion of inactive TGFb-Latent into active TGFb. The invention relates in particular to the use of such an extract for the manufacture of a composition for increasing the concentration of active TGFb1 in the skin, notably in the dermis. | 2010-02-25 |
20100047362 | Method and Pharmaceutical Composition for Improvement of Wound Healing - This invention relates to aqueous solutions of reactive chlorine compounds having the empirical formulae H | 2010-02-25 |
20100047363 | NUTRITIONAL SUPPLEMENT FOR PATIENTS WITH CHRONIC KIDNEY DISEASE - A nutritional supplement for patients having chronic kidney disease. The nutritional supplement comprises: | 2010-02-25 |
20100047364 | Nutrient System for Individualized Responsive Dosing Regimens - Individualized responsive dosing dietary supplement systems, compositions, methods of dosing, and processes of producing the same, which allow a consumer to generate individualistic biological responses/effects. More specifically, a dietary supplement system for generating individualized biological conditions/responses which utilizes ultra-low dosage amounts of vitamins, minerals, amino acids, co-enzymes, and/or other nutrients in a bio-active delivery system which preferably avoids first pass metabolism, such that an individual may take multiple doses of the same or different dietary supplement based on varying desired biological response within each 24 hour period is also disclosed. | 2010-02-25 |
20100047366 | ARTICLES WITH ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY - The present invention relates to articles with antibacterial and antifungal activity, comprising zinc sulphide. The yarns, fibres, filaments and articles according to the present invention may be used especially in the manufacture of any product liable to be placed in contact with bacteria and/or fungi, for instance clothing, rugs, curtains, bedclothes and medical textile materials. The present invention also relates to the use of zinc sulphide for manufacturing yarns, fibres, filaments and/or articles with antibacterial and antifungal properties. | 2010-02-25 |
20100047367 | COMPOUNDS AND METHODS FOR THEIR USE - The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF) by inhibiting the activity of at least one HIF hydroxylase enzyme. | 2010-02-25 |
20100047368 | Compositions and methods for the treatment or prevention of chemoresistant neoplasia - The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject. | 2010-02-25 |
20100047369 | ANTI-TUMOR DRUG, MEDICAMENT, COMPOSITION, AND USE THEREOF - An active polypeptide comprising the amino acid sequence of SEQ ID NO: 3, or having at least 50%, preferably 70%, more preferably 90% identity with the amino acid sequence of SEQ ID NO: 3, or fragments thereof having at least 21 contiguous amino acids, or peptides having at least 50%, preferably 70%, more preferably 90% identity with the amino acid sequence of the fragments, provided that the polypeptide is not SEQ ID NO: 2. A method for inhibiting cancer and/or tumour growth comprising administering to a subject in need thereof an effective amount of the active polypeptide. | 2010-02-25 |
20100047370 | PHARMACEUTICAL COMPOSITION WITH ANTIFUNGAL ACTIVITY CONTAINING CYMBOPOGON NARDUS, ITS PROCESS, AND USE - The present invention refers to the application of extracts of | 2010-02-25 |
20100047371 | COMPOSITIONS AND METHODS FOR ORAL CANCER CHEMOPREVENTION USING BERRY PREPARATIONS AND EXTRACTS - A composition is provided for chemoprevention of an oral cancer or precancerous condition, including an isolated berry preparation admixed with a bioadhesive carrier. The carrier may be a mucoadhesive gel. The berry preparation may be derived from one or more of strawberry, raspberry, red raspberry, and black raspberry. Methods for producing the compositions are provided also. There are also provided methods for chemoprevention of an oral cancer or precancerous condition, utilizing the compositions of the invention. Still further, methods for enhancing stability of an anthocyanin contained in the berry preparation of the invention are provided, along with methods for enhancing efficacy of the compositions. | 2010-02-25 |
20100047372 | ANTIOXIDANT AND PHYSICAL PERFORMANCE EFFECTS OF A GRAPE EXTRACT - A method of enhancing physical performance during exercise by administering an amount of a grape extract effective to treat a subject. A preferred grape extract comprises a concentration of flavanol monomers of greater than about 5% by weight, and more preferably within a range from about 12% by weight to about 50% by weight, and a concentration of flavanol dimers preferably greater than about 2% by weight, and more preferably within a range from about 6% by weight to about 20% by weight. The flavanol monomers preferably include catechin, epicatechin, epicatechin gallate, and gallic acid. The flavanol dimers preferably include procyanidin B1, procyanidin B2, procyanidin B3, procyanidin B4, and procyanidin B2-O-gallate. | 2010-02-25 |
20100047373 | Method for Extracting Plants of the Genus Pelargonium, Extract Produced According to Said Method, and Use Thereof - The present invention relates to a process for the extraction of plants, especially roots, of the plant genus | 2010-02-25 |
20100047374 | COMPOSITION FOR PROTECTING MUSCLE DAMAGE - The present invention aims to provide a composition for protecting a muscle damage having high safety and a stronger muscle damage-protecting effect. The present invention provides a composition for protecting a muscle damage comprising, as an active ingredient, an extract with a lipid-soluble organic solvent of an acetic acid bacterium or preferably an extract with ethyl acetate of an acetic acid bacterium, alkali-stable lipid of an acetic acid bacterium, N-acylsphinganine, sphinganine, amino lipids, or terpenoid compounds. Further, the present invention provides a composition for protecting a muscle damage comprising, as an active ingredient, an extract with a lipid-soluble organic solvent of a vinegar or preferably an extract with ethyl acetate of a vinegar. | 2010-02-25 |
20100047375 | MOULDING DEVICE FOR THE PRODUCTION OF CONTAINERS MADE FROM A THERMOPLASTIC MATERIAL - The invention relates to a moulding device for producing vessels by blowing or stretch-blowing from preforms of a heated thermoplastic material, the device including at least one mould that has at least two half-moulds and a driving mechanism for moving the half-moulds between an open position and a closed position. The two half-moulds are hinged together for rotation about a hinge axis included in the junction plane and perpendicular to the axis of the moulding cavity, the hinge axis being located under the half-moulds, while a mechanism for locking the half-moulds in their closed position are also provided. Each half-mould includes an outer surface area capable of abutment with an inner surface area of the mechanism for locking the half-moulds in their closed position. The locking mechanism is in the form of a clamp capable of clamping the two half-moulds in their closed position. | 2010-02-25 |
20100047376 | NERVE CUFF INJECTION MOLD AND METHOD OF MAKING A NERVE CUFF - A mold for a nerve cuff having a first molding body defining a first molding cavity and a second molding body defining second molding cavity. The first and second molding bodies being mountable to one another thereby providing for the first and second molding cavities to interface. When interfacing the first and second molding cavities and injecting moldable material therebetween provides the nerve cuff following curing of the moldable material. An industrial mold including interfacing first and second cavities is also disclosed. A removable cassette for interposing between a first and a second molding cavity is also disclosed. Methods of making a nerve cuff are disclosed herein. Nerve cuffs produced by the foregoing molds, cassettes, industrial molds and methods are also disclosed. | 2010-02-25 |
20100047377 | MOLDING MACHINE - A molding machine for in-mold-decoration using a film includes a female mold, a male mold capable of engaging with the female mold, and a moving member. The moving member is mounted between the male mold and the female mold. The moving member defines a plurality of cooling passages for coolant flowing therethrough to cool the moving member. The male mold is capable of being moved to resist against the female mold with the moving member being sandwiched therebetween. The female mold, the male mold, and the moving member bound to form a molding space for molding articles. | 2010-02-25 |
20100047378 | INSTALLATION FOR BLOW MOULDING HOLLOW BODIES, COMPRISING A PRESSURIZED TEMPERATURE-CONTROLLED FLUID CIRCUIT - Installation ( | 2010-02-25 |
20100047379 | Injection molding tool with closable hot channel nozzle - In an injection molding tool with at least one hot channel nozzle ( | 2010-02-25 |
20100047380 | OPHTHALMIC LENS PRECURSOR AND LENS - This invention discloses Lens Precursors and apparatus for generating an ophthalmic lens precursor with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic Lens Precursor is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture. | 2010-02-25 |
20100047381 | SYSTEM FOR THE PRODUCTION OF ORE WITH GREEN AGGLOMERATES CONTAINING A PROPORTION OF FINES CROSS REFERENCE TO RELATED APPLICATIONS - A plant for the production of ore comprising a proportion of fines, additives and green agglomerates optionally containing a binder, provided with an outer coating consisting of a combustible containing fine-grained carbon, such as coke. In the plant, the ore is mixed with the additives and the optionally available binder. The mixture is pelletized and the green agglomerates thus formed are coated with the combustible, whereby the combustible is introduced into an agglomeration drum. In order to enable continual production of homogeneous-quality green agglomerates, the mixture is pelletized in the agglomeration drum and the combustible is added in an area of the longitudinal extension of the agglomeration drum where the size of the green agglomerates formed in the agglomeration drum is sufficient for further processing. | 2010-02-25 |
20100047382 | Defoaming Device and Forming Device With The Same - A defoaming device for a viscosity fluid, equipped with a container or containers having a receiving section for the viscosity fluid, and a supply port and an outlet for the viscosity fluid, communicated with the receiving section, the defoaming device being provided with: a supply pipe for supplying the viscosity fluid to the supply port; a supply control device for the viscosity fluid at the supply port; a sprinkler for discharging the viscosity fluid supplied from the supply port into the receiving section; a pressure control device for controlling a pressure in the receiving section; an outlet tube for discharging the viscosity fluid from the outlet; and an outlet control device for the viscosity fluid in the outlet, as well as, a molding system provided with the defoaming device. The defoaming device of the present invention can effectively defoam a high viscosity fluid such as a liquid silicone rubber, does not need a complicated defoaming device, and can continuously supply the defoamed viscosity fluid. In addition, the molding system of the present invention can provide a molded product in which no air bubbles or chips occur. | 2010-02-25 |
20100047383 | Injection Molding Apparatus Having A Nozzle Tip Component For Taking A Nozzle Out-of-Service - An injection molding apparatus includes a plurality of valve-gated nozzles, each nozzle having a respective valve pin that is actuated by an actuator. A nozzle tip component for taking one of the valve-gated nozzles of the injection molding apparatus out-of service, wherein the nozzle tip component has a surface that grips the respective valve pin to lock the valve pin in an out-of-service position thereby preventing flow of molding material into an associated mold cavity and causing disengagement of the valve pin from the actuator. | 2010-02-25 |
20100047384 | METHODS OF PRODUCING TRANSFORMATION COMPETENT BACTERIA - A method of producing transformation competent bacteria, comprising the steps of: (i) transforming a bacteria that is not naturally transformation competent with a plasmid, wherein said plasmid comprises a comX gene sequence encoding a ComX protein or functional part or derivative or variant thereof under the regulatory control of a promoter which is inducible by a transcription initiator, (ii) contacting said transformed bacteria with said transcription initiator to initiate transcription of said comX gene sequence is provided. Also provided are plasmids, transformed bacteria, transformation competent bacteria, mutant bacteria and food products comprising said mutant bacteria. | 2010-02-25 |
20100047385 | CULTURE METHOD FAVORISING THE PRODUCTION OF K2 VITAMIN BY LACTIC BACTERIA AND APPLICATIONS THEREOF IN THE PREPARATION OF FOOD PRODUCTS - The present invention relates to a method for increasing the amount of K2 vitamin obtained by culturing at least one stem of a lactic bacteria that produces K2 vitamin, wherein the culture of said stem is realized in resting-cells conditions so that the amount of K2 vitamin produced by the resting-cells culture is higher by a ratio of at least 1.2 to that obtained by the culture of said stem under standard fermentation conditions. The present invention also relates to the biomass obtained from the culture of a lactic bacteria producing K2 vitamin according to the above method. The invention further relates to a method for producing K2 vitamin, to a method for preparing food products, including fermented products and/or fresh diary products, enriched with K2 vitamin, and to the food products thus obtained. | 2010-02-25 |
20100047386 | Method of making alcohol concentrate - One embodiment of the present invention is method for making an alcohol concentrate using a nested batch fermentation process, wherein multiple rounds of wort fermentation, distillation and refortification, is described. The rounds are repeated until the desired concentration of fermented wort is obtained. Another embodiment of the present invention is a method for a continuous fermentation process, wherein portions of the fermentation are distilled and the remaining wort is returned to the active fermentation. This process is repeated until the desired concentration of the fermented wort is obtained. Yet another embodiment of the present invention is a method for extraction of hops compounds, wherein the distilled alcohol from the nested or continuous fermentation process is used. | 2010-02-25 |
20100047387 | TRANSFORMED SACCHAROMYCES YEAST STRAINS HAVING REDUCED ETHANOL PRODUCTION BY FERMENTATION - The invention concerns transformed yeast strains belonging to the genus | 2010-02-25 |
20100047388 | Lipolytic Enzyme Variants - The inventors have developed improved polypeptides by substituting or deleting specified amino acids in fungal lipolytic enzymes. More particularly, the polypeptides result in a reduction of dough stickiness when they are added to a dough. The polypeptides may particularly have activity on polar lipids. | 2010-02-25 |
20100047389 | FOOD OR BEVERAGE CONTAINING HIGHLY UNSATURATED FATTY ACID,AND PROCESS FOR PRODUCTION THEREOF - [PROBLEMS] To prevent the generation of deterioration odor caused by the oxidation of a food or beverage containing a highly unsaturated fatty acid (HUFA)-containing fat-and-oil during storage, and provide a HUFA-containing liquid composition having excellent long-term flavor stability. | 2010-02-25 |
20100047390 | FERMENTED PRODUCTS CONTAINING DIETARY FIBERS AND METHODS FOR PREPARING THE SAME - gum, in particular from | 2010-02-25 |
20100047391 | REDUCED-SALT DAIRY PRODUCT WITH IMPROVED TASTE - The present invention relates to a method for preparing a dairy product with reduced sodium, wherein a yeast extract comprising at least 30% w/w 5′-ribonucleotides, on the basis of sodium chloride free dry matter, is added to a dairy composition used in the production of dairy product with reduced sodium. Preferably, a yeast extract is used wherein the total amount of 5′-GMP plus 5′-IMP is at least 15% w/w on the basis of sodium chloride free dry matter. The method of the invention may advantageously be used since off-tastes are masked and salt perception is enhanced. | 2010-02-25 |
20100047392 | Enzymes Having Alpha Amylase Activity and Methods of Making and Using Them - The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures. | 2010-02-25 |
20100047393 | PROBIOTIC (INFANT) FOOD - The invention relates to foods, such as infants and children's food and dietary supplements for infants and children. The invention provides a composition comprising a lipid source, a carbohydrate source and a protein source, characterized in that the composition further contains the | 2010-02-25 |
20100047394 | PRODUCT CONTAINING LIVING PROBIOTIC MICROORGANISMS - The present invention relates to a liquid fermented natural product which contains live probiotic microorganisms in an amount of 10 | 2010-02-25 |
20100047395 | COMPOSITION AND USES THEREOF - A composition comprising one or more starches, an amount of water and an encapsulating agent, wherein the encapsulating agent encapsulates the one or more starches and the amount of the liquid, is provided. Also, techniques for producing a composition are provided. The techniques include combining one or more starches, an amount of a liquid and an encapsulating agent, wherein the encapsulating agent encapsulates the one or more starches and the amount of the liquid, into a composition. Techniques are also provided for using a composition to create a food product. | 2010-02-25 |
20100047396 | METHOD FOR OBTAINING VARIANTS OF LACTIC ACID BACTERIA USABLE FOR PRODUCING VITAMIN K2 AND APPLICATION TO THE PREPARATION OF FOOD PRODUCTS - The present invention relates to the production of variants of lactic bacteria stems that produce, under standard fermentation conditions, at least about 1.2 times more K2 vitamin than the starting lactic bacteria stems cultured in the same conditions. The invention further relates to a method for preparing food products, including fermented products and/or fresh diary products, enriched with K2 vitamin, and to the food products thus obtained. | 2010-02-25 |
20100047397 | Coated Pet Chew and Method of Making - Disclosed is a coated pet chew and a method of making. The coated pet chew comprises a substrate coated with unrefined collagen. | 2010-02-25 |
20100047398 | Non-Bitter Sodium-Free or Low-Sodium Salt Composition - A sodium-free or low-sodium seasoning composition, comprising an acidulant selected from the group consisting of citric acid, tartaric acid, fumaric acid, lactic acid and mixtures thereof; a potassium salt; a calcium salt; a magnesium salt; and rice flour. | 2010-02-25 |
20100047399 | Consumable Porous Food Product Covered with a Non-Porous Coating - A consumable liquid is orally drawn into a food product and absorbed by an internal structure of the product, before the product is consumed. The product includes a substantially non-porous coating covering its outer surface. In one embodiment, a channel with a porous filling therein provides fluid communication so that when one opening is immersed in a liquid and a reduced pressure is orally applied to the other opening, the liquid is drawn into the filling and absorbed by the internal structure. | 2010-02-25 |
20100047400 | SYSTEM AND METHOD FOR FORMING A CO-EXTRUDED FOOD PRODUCT - Food products and the processes for forming/manufacturing the food products are disclosed. An exemplary food product comprises one or more extruded components (e.g., vegetable, fruit, dairy, meat, flavoring, spice, coloring, particulate, or combinations thereof); and one or more extruded collagen layers substantially encasing the extruded component(s). Another exemplary food product is disclosed as comprising an extruded component; and a carrier co-extruded with the first extruded component, the carrier comprising a matrix adhered to the first extruded component and an additive suspended in the matrix | 2010-02-25 |
20100047401 | METHOD AND COMPOSITION FOR EXTRUDED PET FOOD PRODUCT - A method for forming a pet food product includes supplying a basal formula to a feed section of an extruding system, passing the basal formula through the extruding system, supplying a particulate dough to the basal formula downstream of a compression section of the extruding system, mixing the basal formula and the particulate dough to form a pet food product, and forming the pet food product into discreet pieces. The formed pet food product includes an extruded basal portion and a granular portion mixed throughout the extruded basal portion. | 2010-02-25 |
20100047402 | Energy-Differential Microwaveable Food Package - A food package is provided having two different food products disposed within a common flexible film wrapper. A portion of the flexible film wrapper adjacent a first of the food products is adapted to at least partially shield microwave radiation from the first food product to a greater degree than the second food product when both are heated together in the film wrapper in a microwave oven. | 2010-02-25 |
20100047403 | POUCH CONTAINER FOR FOOD PRODUCT - A pouch container ( | 2010-02-25 |
20100047404 | PACKAGING LAMINATE - The invention relates to a packaging laminate comprising at least one base layer of paper or paper board and at least one liquid barrier layer, said paper or paper board being sized with a formulation comprising a sizing agent selected from the group consisting of ketene dimers and multimers, succinic anhydrides, rosins and mixtures thereof, and also comprising an acrylamide based polymer The invention further relates to the production and use of a packaging laminate and a package for food or beverage products and its production. | 2010-02-25 |
20100047405 | ABSORBENT PAD TO PRESERVE FRESHNESS FOR CONSUMER FOOD STORAGE - The present disclosure is directed to an absorbent pad having an active agent to preserve food products or other perishable merchandise, that has a pad architecture, including the specific arrangement of the absorbent layers and active agents in the absorbent pad, that affects the availability and timing of release of the active agents to preserve the freshness of food products that are stored at home by a consumer in the consumer's own food storage containers. | 2010-02-25 |
20100047406 | METHOD FOR DISPENSING MILK PORTIONS IN DRINK PREPARATION MACHINES - The invention relates to a method for dispensing milk portions in drink preparation machines having a milk fill level monitoring unit for a milk container. According to the method, one delivery of a milk portion from the milk container, said delivery being controlled by a device control electronic system, is only carried out completely and with a sufficient quantity of milk when during the delivery of the milk portion, the milk fill level monitoring unit signals a drop in the fill level of the milk below a threshold value. | 2010-02-25 |
20100047407 | DEVICE FOR HEATING AND/OR FROTHING A BEVERAGE - The present invention relates to a device for heating and/or frothing a beverage ( | 2010-02-25 |
20100047408 | Banana Treatments - There is provided a method for treating bananas comprising contacting said bananas with a liquid composition comprising a cyclopropene molecular encapsulation agent complex, wherein the duration of said contacting is from 1 second to 4 minutes. | 2010-02-25 |
20100047409 | Apparatus and method for molding cooked rice - There is provided a cooked rice molding apparatus capable of efficiently making back rolled sushi in which sushi rice is arranged so as to be directed to the surface side. When both ends of a rolling-up bamboo plate | 2010-02-25 |
20100047410 | Method For Making Pastry Shells - A method for making a pastry shell includes the provision of an upward-facing female die, including an open-bottomed baking ring, and a downward-facing male die, and urging the two dies toward each other with a selected volume of dough inserted therebetween such that the male die is inserted concentrically into the female die to form the dough into an unbaked pastry shell conforming substantially to the die space defined between the male and female dies and having a substantially flat, horizontal floor and vertical annular side walls that intersect the floor at substantially a right angle. The baking ring, gasket and unbaked pastry shell define an assembly that is then removed from the forming apparatus, conveyed to a separate oven and baked in the oven such that the baking ring supports the walls of the pastry shell during the conveying and the baking of the shell. | 2010-02-25 |
20100047411 | BREADING MACHINE AND METHODS OF OPERATION - A breading machine, and improvements thereto, for use in high volume food production is disclosed. In accordance with an embodiment of the present invention, an improved breading machine includes a side-mounted feed hopper, a low pressure auger assembly including an auger transfer box with an input port for accepting a cross-feed screw and paddle, and an output port for transferring coating material to a vertical screw. The improved breading machine also includes a substantially cylindrical, rod-based spreader assembly and a transport conveyor belt for feeding the spreader assembly within a top hopper of the breading machine. The improved breading machine further includes a vibrating filter assembly to filter out clumps of coating material while allowing un-clumped material to be re-used within the breading machine. | 2010-02-25 |
20100047412 | Post Harvest Treatment of Fruit - Methods for protecting fruit, vegetables and ornamentals against post harvest microbial decay by applying systemic acquired resistance inducers such as phosphorous acid and/or one or more of the alkali metal salts of phosphorous acid in combination with Imazalil. | 2010-02-25 |
20100047413 | METHOD OF USING AMPHIPHILIC MULTIBLOCK COPOLYMERS IN FOOD - The present patent discloses a method of processing food in a manner so that the processed food can be stored in freezer or other similar environment for an elongated period of time with reduced amount of freezer burns or undesirable ice crystal formation, in a manner so as to maintain food freshness over a longer period of time, or in a manner so as to prevent protein aggregation over an elongated period of time. An embodiment of this method uses amphiphilic multiblock copolymers, such as poloxamer, meroxapols, poloxamines or polyols in such food processing and handling. | 2010-02-25 |
20100047414 | ORGANIC PRODUCE WASH SYSTEM - The present application describes a produce wash system for dispersing carbon dioxide into a liquid medium which includes a container containing carbon dioxide gas which is connected to another container or pipe capable of containing a liquid medium so that the gas from the first container is capable of being dispersed into the liquid medium of the second container or pipe. | 2010-02-25 |
20100047415 | INK-JETTABLE FLAVORED FLUIDS FOR PRINTING ON EDIBLE SUBSTRATES - Food grade flavored fluids for use in printing on edible substrates and methods for applying the food grade flavored fluids to edible substrates are described. The food grade flavored fluids have characteristics that render them suitable for ink-jet printing onto the surfaces of a variety of edible substrates. | 2010-02-25 |
20100047416 | MULTILAYER SEAMLESS TUBULAR CASING BASED ON POLYAMIDE FOR MOLD COOKING - The present invention relates to a coextruded, if appropriate biaxially stretched seamless multilayer tubular casing, and also to use thereof for encasing pasty or liquid goods, such as, for example, producing sausage in molds. | 2010-02-25 |