09th week of 2015 patent applcation highlights part 40 |
Patent application number | Title | Published |
20150056556 | PHOTOSENSITIVE COMPOSITION AND PHOTORESIST - A photosensitive composition and a photoresist are provided. The photoresist is formed by compounding a photosensitive composition. The photosensitive composition includes a binder agent, a first photomonomer, and a photo initiator. The first photomonomer has at least a lactic oligomer and at least two unsaturated acrylic functional groups, wherein the first photomonomer has an amount of about 25-95 parts by weight relative to 100 parts by weight of a solid content of the binder agent. The photoinitiator has an amount of about 0.5-15 parts by weight relative to 100 parts by weight of the solid content of the binder agent. | 2015-02-26 |
20150056557 | CHEMICALLY AMPLIFIED POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN USING THE SAME - A chemically amplified positive-type photosensitive resin composition including a compound represented by the following formula (1), having a melting point of 40° C. or lower at 1 atm, a resin whose solubility in alkali increases under the action of an acid, and a photoacid generator. In the formula, R | 2015-02-26 |
20150056558 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME - A photoacid generator compound has the formula (I): | 2015-02-26 |
20150056559 | IMMERSION LIQUID, EXPOSURE APPARATUS, AND EXPOSURE PROCESS - An immersion liquid is provided comprising an ion-forming component, e.g. an acid or a base, which has a relatively high vapor pressure. Also provided are lithography processes and lithography systems using the immersion liquid. | 2015-02-26 |
20150056560 | PHOTOSENSITIVE CONDUCTIVE PASTE AND METHOD OF PRODUCING CONDUCTIVE PATTERN - A photosensitive conductive paste includes an epoxy acrylate (A) including a urethane bond, a photopolymerization initiator (B), and a conductive filler (C), wherein an added amount of the conductive filler (C) is 70 to 95% by weight with respect to the total solids in the photosensitive conductive paste. | 2015-02-26 |
20150056561 | Composite Holographic Optical Diffuser Structure with High Frequency Overlay and Method of Fabrication Thereof - The optical diffuser mastering of the subject invention includes legacy microstructure surface relief patterns, along with smaller ones, overlaid on the larger ones. The characteristic features produced by the present invention will be found useful to eliminate visible structures in/on optical diffusers, such as those used in movie projection screens (utilizing either coherent (i.e., laser-generated) and non-coherent (e.g., lamp-generated) light), head-up displays (HUDs), laser projection viewing, etc., as the present invention produces much sharper images than those afforded by traditional holographic optical diffusers. | 2015-02-26 |
20150056562 | CANDLE MAGAZINE - A candle magazine has a multiplicity of deep-drawn cup-like structures in which there is provided in each case one candle composed of a combustible material and of a wick. A candle, a method for producing a candle or a candle magazine, and a deep-drawing apparatus are also provided. | 2015-02-26 |
20150056563 | DUAL VENTURI FOR COMBUSTOR - The present invention relates to a dual venturi for a combustor and, more specifically, to a dual venturi for a combustor which can control, in two stages, the amount of gas and air supplied to a burner provided in a water heater, wherein a motor and a damper are combined in such a manner that the damper is rotated by the driving of the motor, and thus the damper simultaneously opens or closes the inlet for secondary air and gas, thereby efficiently controlling the quantity of heat. The dual venturi comprises: a housing which has a first gas inlet and a second gas inlet on one side of the upper part thereof, and which has an interior divided by a partition wall such that a first passage and a second passage are formed; and an opening and closing means which is disposed in the housing, has an upper part connected to the second gas inlet such that gas flows therein, and controls the flow of air and gas by closing or opening the second passage as a damper is rotated by a motor provided on the exterior of the housing. | 2015-02-26 |
20150056564 | DUAL VENTURI FOR COMBUSTION APPARATUS - The present invention relates to a dual venturi for a combustion apparatus, and more particularly, to a dual venturi for a combustion apparatus that is capable of effectively controlling calorific power since the amount of gas for a burner provided in a water heater and the amount of supplied air are controlled in two phases, and a motor and a damper are coupled to each other so that the damper opens or blocks inlets for secondary air and the gas at the same time that the damper is rotated by the driving of the motor. The present invention includes: a housing that is a cylindrical duct where a first passage and a second passage are formed therein partitioned by a partition wall, wherein a first gas inlet pipe is formed in one side portion of the first passage; a damper which is disposed in the second passage of the housing so as to open or block the flow of the secondary air according to the state of rotation, wherein a damper hole is formed in the damper; a secondary gas inlet pipe having one end portion coupled with the damper, wherein a secondary gas outlet is formed on the same circumference as the damper hole, a secondary gas flows into the other end portion, and the secondary gas outlet and the damper hole selectively communicate with each other according to the angle of rotation of the damper; and a motor for rotating in a coupled state with the damper which is disposed outside of the housing. | 2015-02-26 |
20150056565 | TOOL FOR BONDING ORTHODONTIC BRACKET - The present invention relates to a tool for adhering an orthodontic bracket, comprising: a pair of bracket holding portions for holding a bracket to be bonded to teeth while approaching or separating from each other; and a pair of handle portions connected to the pair of bracket holding portions, for controlling the bracket holding portions to allow the same to approach or separate from each other, wherein a scale for measuring the height of a bracket for the end of teeth is formed in at least any one of the pair of bracket holding portions. Therefore, an operation is convenient, measurement is easy and measurement time can be reduced since the tool has a simple and uncomplicated structure. In addition, it is possible to improve the effectiveness of orthodontic treatment since a bracket can be bonded by precisely setting the height of the bracket. | 2015-02-26 |
20150056566 | Maxillary Skeletal Expander Using Mini-Screw - A maxillary skeletal expander includes a pair of bodies, an extending screw adjusting a space between the pair of bodies, guide rails having both sides inserted into the pair of bodies and guiding a movement of the bodies, a key hole integrally formed with the extending screw, screw insertion portions integrally formed with the bodies and having screw insertion holes guiding mini-screws implanted to an upper jaw, arms having one end fixed to the bodies and the other end extending toward teeth, and a teeth fixing part integrally formed with the arms and fixed to teeth of a patient. | 2015-02-26 |
20150056567 | PHOTON INDUCED ACOUSTIC STREAMING DEVICE AND METHOD - A device and method of using a device for photon-induced endodontic and periodontic applications includes a power source, a trigger coupled to the power source and circuit elements initiated by the trigger. The circuit elements include a timing circuit and a driver. A light source is coupled to the circuitry elements wherein and driver controls the period, cycle, and pulse generation of the light source to create photon induced acoustic waves. The optical assembly includes a fiber optic cable and an output tip and is coupled to the light source. This optical assembly refracts light from the light source and photon induced acoustic waves exit the output tip in a pre-determined pattern. | 2015-02-26 |
20150056568 | OPTICAL THERAPEUTIC TREATMENT DEVICE - Methods and devices for Live Biofilm Targeted Thermolysis (LBTT) are disclosed. The disclosed LBTT methods can be used for thermolysis and coagulation of the live periodontal Biofilm with incandescent light and a targeting agent as heat sink. A delivery assembly can be used to deliver the incandescent light generated through the secondary quantum optical and thermal emissions from a carbonized near infrared diode laser delivery fiber, otherwise known as a “hot tip,” to an application region that includes live biofilm. With this novel targeted approach of exploiting the incandescent hot tip's radiant energy (i.e. its optical and thermal emissions), the physical nature of the targeted live biofilm in the periodontal pocket is changed from a mucinous liquid-gel, to a semi-solid coagulum, which then facilitates its removal from the effected pocket, with traditional mechanical SRP periodontal techniques. | 2015-02-26 |
20150056569 | Method for Pretreatment of Wastewater and Recreational water with Nanocomposites - A method and a dental implant system for accessing selected intra-cavity locations there-through that includes: (a) a dental implant having a plurality of openings configured for being implanted in an intra-cavity area of a patient, wherein each one of the plurality of openings allows access from an external area of the dental implant to a space in the intra-cavity area between the implant and a jawbone of the patient, when the dental implant is installed in the intra cavity; and (b) one or more directing element that is removably securable to the dental implant, wherein the directing element includes openings and is configured to allow access to one or more specific locations at this space through a selected at least one of the plurality of openings of the dental implant, when secured thereto. | 2015-02-26 |
20150056570 | DENTAL WATER JET - An apparatus for oral hygiene includes a compartment which is adapted to store a cleaning fluid in a pressurized state. The compartment has a pressure sustaining mechanism which is manually operated, and is capable of maintaining the cleaning fluid in the pressurized state. Further, the apparatus includes a detachable delivery assembly which is operationally coupled to the compartment. The detachable delivery assembly is capable of being operated by a user for controllably ejecting the pressurized cleaning fluid at a high velocity from the compartment. The ejected cleaning fluid is capable of being used by the user for providing oral hygiene. | 2015-02-26 |
20150056571 | Cross-Fluted Endodontic Instrument - An endodontic instrument adapted to be axially reciprocated within a root canal to remove material from walls of the root canal. The endodontic instrument includes an elongate shaft and a working portion. The elongate shaft includes a proximal end adjacent a handle and a distal end terminating at a tip spaced from the proximal end by the length of the instrument. The working portion includes a first helical fluted cutting surface for removing material from the walls of a root canal and a second helical fluted cutting surface for removing material from the walls of a root canal. The first helical fluted cutting surface and second helical fluted cutting surfaces are formed in opposing left-hand and right-hand directions such that material is removed form the walls of a root canal when the instrument is rotated in either a first or a second direction. | 2015-02-26 |
20150056572 | DENTAL PROSTHESIS, IN PARTICULAR ON IMPLANTS, OPTIONALLY FOR THE REPLACEMENT OF AN ENTIRE DENTAL ARCH, METHOD AND KIT FOR MAKING IT - The invention concerns a dental prosthesis ( | 2015-02-26 |
20150056573 | DENTAL IMPLANT FOR A JAW WITH REDUCED BONE VOLUME AND IMPROVED OSSEOINTEGRATION FEATURES - A dental implant has a body with a porous metal portion for engaging bone. The porous metal portion has an outer coronal to apical height and an outer diameter. Both the height and diameter are about 4 mm to about 6 mm. This permits the implant to be placed on a jaw with a reduced bone volume. | 2015-02-26 |
20150056574 | PROCESS FOR PROVIDING A TOPOGRAPHY TO THE SURFACE OF A DENTAL IMPLANT - A process for providing a topography to the surface of a dental implant, the surface being made of a ceramic material having yttria-stabilized zirconia, the process including: providing a macroscopic roughness to the surface of the dental implant by a mechanical process and/or injection molding technique; and etching at least a part of the roughened surface, wherein etching is carried out using an etching solution having hydrofluoric acid at a temperature of 70° C. at least, such that discrete grains or agglomerates of grains are removed from the yttria-stabilized zirconia, thereby forming recesses and cavities in the roughened surface is disclosed. | 2015-02-26 |
20150056575 | DENTAL DEVICE, AND METHOD FOR LINKING PHYSICAL AND DIGITAL DATA FOR DIAGNOSTIC, TREATMENT PLANNING, PATIENT EDUCATION, COMMUNICATION, MANUFACTURING, AND DATA TRANSFER PURPOSES - A dental device and/or process include at least one scaled and shaped linking component ( | 2015-02-26 |
20150056576 | Computer-Implemented Dental Restoration Design - Computer-implemented methods of designing dental restorations and systems for performing the described methods are provided. In an embodiment, a method includes providing a virtual three dimensional representation of at least a portion of the patient's dentition that includes at least one preparation tooth, identifying a preparation margin on the virtual three dimensional representation, placing an arch form of a virtual tooth library in alignment with the virtual three dimensional representation, and proposing an initial restoration design based upon a tooth design obtained from the virtual tooth library. | 2015-02-26 |
20150056577 | VEHICLE CREW TRAINING SYSTEM - A computer based simulation system for virtual training for vehicle crews is disclosed. The vehicle crew training system (VCTS) simulates crew positions for different military vehicles. Two or more crewman modules are networked together to support a partial or full vehicle crew. The crewman modules are self-contained devices that are modular in hardware and software design, easily reconfigurable, and that require minimal facility space, allowing use in restricted environments such as trailers. The VCTS is modular at the crew position level; crewman modules are added or deleted as required to meet a particular training need. One of the crewman modules can be a gunner module, which provides an unrestricted view of the simulated environment to the gunner by means of a display and a simulated vehicle-mounted weapon. | 2015-02-26 |
20150056578 | METHODS AND SYSTEMS FOR GAMIFIED PRODUCTIVITY ENHANCING SYSTEMS - Systems and methods for a gamified Productivity Enhancing System. | 2015-02-26 |
20150056579 | PORTION CONTROL DEVICE - An adjustable portion control device is disclosed. The portion control device can be comprised of a portion container with a circular interior, a circular rotating platform, and a measurement indicator located upon the portion container. The rotating platform is lowered within the portion control container to an adjustable target weight indicated by the measurement indicator for providing an appropriate amount of food for that target weight. | 2015-02-26 |
20150056580 | PRONUNCIATION CORRECTION APPARATUS AND METHOD THEREOF - The present invention provides a pronunciation correction method for assisting a foreign language learner in correcting a position of a tongue or a shape of lips when pronouncing a foreign language. According to a implementation of this invention, the pronunciation correction method comprises receiving an audio signal constituting pronunciation of a user for a phonetic symbol selected as a target to be practiced, analyzing the audio signal, generating a tongue position image according to the audio signal based on the analysis results, and displaying the generated tongue position image. | 2015-02-26 |
20150056581 | SYSTEM AND METHOD FOR LEARNING MATHEMATICS - The present invention provides a system for teaching mathematics comprising: a student input module configured to select an exercise from a group consisting of homework, a race or competition, and practice; a teacher input module configured to select an exercise parameter from a group consisting of setting a home work exercise from scratch, revising a home work exercise based on student results or comparing results between different groups; a question selection module to randomly generate a question depending on the exercise selected and/or the parameter; an answer module configured to parse a response to the question, and to display a result, a dynamically generated graphic and/or any applicable explanation depending on the response; and an avatar module configured to vocalise the explanation depending on a predetermined set of rules for vocalising certain mathematical explanations. | 2015-02-26 |
20150056582 | COMPUTER-IMPLEMENTED OPERATOR TRAINING SYSTEM AND METHOD OF CONTROLLING THE SYSTEM - A computer-implemented training system includes a) a plant replica server; b) a virtual environment reproducer; and c) a motion sensing system. The plant replica server has a plant replica associated with a simulated plant model. The virtual environment reproducer is configured to reproduce a virtual environment of the simulated plant model, based on the plant replica. The motion sensing system is configured to sense motions of a field operator in the virtual environment. The motion sensing system is configured to send an update associated with the sensed motions to the plant replica server. The plant replica server is configured to receive the update from the motion sensing system, and to update the plant replica based on the first type of update associated with the sensed motions, and to reflect the first type of update to the virtual environment reproduced by the virtual environment reproducer. | 2015-02-26 |
20150056583 | UNDERGROUND MINING TRAINING SIMULATOR - Training an operator of an underground mining machine. The training includes generating a simulated training environment that includes a simulated underground mining machine and generating an interface related to a training lesson for the simulated underground mining machine. The training lesson is related to performing a simulated cutting operation with the underground mining machine. The training also includes receiving an operator input from an operator input device related to the simulated cutting operation with the underground mining machine, executing the simulated cutting operation within the simulated working environment based on the operator input, determining an amount of simulated mining material removed from a cutting face of the simulated working environment during the simulated cutting operation, and generating an indication of the amount of simulated mining material removed from the cutting face of the simulated working environment during the simulated cutting operation. | 2015-02-26 |
20150056584 | SYSTEM AND METHOD FOR MANUAL WELDER TRAINING - A method for manual welder training that includes providing a welding training apparatus that includes both hardware and software components and that is operative to gather and process data in real time, wherein the data is derived from an actual training exercise conducted by a welding trainee; selecting training objectives from a predetermined number of predefined objectives; initializing a curriculum, wherein the curriculum is based on the selected training objectives; performing at least one training exercise, wherein the training exercise is a component of the curriculum; providing real-time feedback to the trainee, wherein the real-time feedback is based on the performance of the trainee during the training exercise; evaluating the performance of the trainee based on data gathered and processed during the training exercise; optionally, adapting the curriculum based on the trainee's performance evaluation; and awarding credentials or certifications to the trainee following successful completion of the curriculum. | 2015-02-26 |
20150056585 | SYSTEM AND METHOD MONITORING AND CHARACTERIZING MANUAL WELDING OPERATIONS - A system and method for monitoring manual welding that includes a welding system that further includes hardware and software components for gathering and processing data in real time, wherein the data is derived from an actual welding exercise conducted by a welder; providing the system with part information, process variable control targets, and acceptability limits; selecting a part to be welded from the part information; indicating a production task to be completed on the part; performing the indicated production task; providing real-time feedback to the welder performing the task; evaluating the quality of the welder's performance of the task based on the process variable control targets and acceptability limits; if necessary, requiring remedial action with regard to the quality of the performance of the task; and storing data gathered from the evaluation of the performance of the task. | 2015-02-26 |
20150056586 | WELDING TRAINING SYSTEM - A system for training welders that includes a data generating component, a data capturing component and a data processing and visualization component. The data generating component operates in real time and derives data from an actual manually-executed weld and further includes a weld process-specific jig, a calibration block positioned on the jig, wherein the geometric configuration of the calibration block is specific to a particular type of weld joint, a weld coupon positioned on the welding process-specific jig adjacent to the calibration block, a welding gun for use by a trainee, wherein the welding gun is operative to form the weld; and at least one target mounted on the welding gun that is recognized by the data processing and visualization component for providing multidimensional position and orientation feedback to the trainee. | 2015-02-26 |
20150056587 | METHOD AND SYSTEM FOR AUTOMATING THE SCORING OF TASK INFORMATION - A method and system for scoring task information. Through the use of an electronic time management device, such as a cell phone or other portable digital computer based device programmed to support this method, a user enters a description of a task and when the task should be completed. This information is then communicated to a scoring system, and the information is scored without human intervention and points are given. Optionally, if the information cannot be automatically scored, it is scored by a person. These points can be banked and then be used toward a socially desirable reward, such as sending text messages or playing music or watching videos. This is particularly effective in teaching time management skills to young students who may have attention deficit hyperactivity disorder (ADHD). | 2015-02-26 |
20150056588 | Electronic Health Care Coach - An Electronic Health Care Coach is provided for patients that have trouble taking their medications or remembering to test for such things as blood sugar and the like. The Electronic Health Care Coach provides voice prompts to the patient to determine compliance with dosing of medications or routine testing. The Electronic Health Care Coach takes the form of a stuffed toy such as a teddy bear and utilizes input sensors that are contained by an appendage of the stuffed toy that are sensitive to human touch. Multiple prompts are employed depending on the responses received. Statistics on patient compliance are collected. The stuffed toy and related voice prompts and input sensors provide a friendly and easy to use reminder system for medications and routine testing that creates a positive experience for the patient, thus increasing patient compliance. | 2015-02-26 |
20150056589 | WELLNESS MANAGEMENT METHOD AND SYSTEM BY WELLNESS MODE BASED ON CONTEXT-AWARENESS PLATFORM ON SMARTPHONE - A device, method and system processes data about the user for determining and recommending a health/wellness action to the user. The action determined can be based on: (1) current biometric and/or motion data about the user (from the sensors), and (2) current health/medical information or condition about the user (from the user's personal information, e.g., health library or programmed into the smartphone). Specific information about the user is taken into consideration when recommending user action, such as the user's specific health or medical conditions. | 2015-02-26 |
20150056590 | APPARATUS AND METHOD FOR TRADITIONAL ROCK CLIMBING TRAINING - A rock climbing anchor and related methods are described. The climbing anchor comprises a body and a base member or skeleton. The body allows for traditional lead climbing protection to be placed and secured. The body can be molded around the skeleton. The skeleton serves to support the body against large forces generated by a falling climber, and to act as a secondary safety measure against a fall. Various scenarios or arrangements can be provided or created on a climbing wall to train a climber or give a climber a variety of experiences. | 2015-02-26 |
20150056591 | DEVICE FOR TRAINING USERS OF AN ULTRASOUND IMAGING DEVICE - Disclosed are methods and devices for simulating ultrasound procedures and for training ultrasound users. Additionally disclosed are methods and devices for simulating needle insertion procedures, such as amniocentesis procedures, and for training physicians to perform such needle insertion procedures. | 2015-02-26 |
20150056592 | MEDICAL TREATMENT SIMULATION DEVICES - Medical treatment simulation devices are disclosed. One device includes an overlay, a tracheostomy structure, one or more tubes, at least one sensor, and at least one feedback device. The overlay is configured to be secured to a subject. The overlay is configured to cover at least a portion of a neck and upper torso of the subject. The tracheostomy structure is provided in a neck portion of the overlay. The one or more tubes are positioned within the overlay. The tubes are connected to the tracheostomy structure. The sensor is coupled to the tracheostomy structure and configured to detect a manipulation of the tracheostomy structure. The feedback device is coupled to the overlay. The feedback device is configured to provide feedback based on the manipulation detected by the at least one sensor. | 2015-02-26 |
20150056593 | TAXIDERMY MANNEQUIN AND METHOD OF MAKING THE SAME - A method of manufacturing a taxidermy mannequin includes providing a mold having an open end, a wall having an internal surface and an opposing external surface, and an internal cavity surrounded by the internal surface of the wall. The method further includes applying a layer of a mold release material to a portion of the internal surface, applying a powder material on an exposed surface of the mold release material, applying a layer of a glue mixture on an exposed surface of the powder material and the mold release material layer, applying a granular or fibrous material on an exposed surface of the glue mixture layer, allowing the glue mixture to at least partially dry, filling at least a portion of the internal cavity of the mold with a liquid expandable urethane foam, allowing the expandable urethane foam to expand and harden, and removing the taxidermy mannequin from the mold. | 2015-02-26 |
20150056594 | SYSTEMS AND METHODS FOR MEASURING EDUCATIONAL INPUTS - A computer-implemented method for measuring educational inputs is described. A plurality of educational inputs are obtained. The inputs may include at least one formal educational input and at least one informal educational input. A value for each educational input is determined. Each determined value is normalized with respect to other determined values. An educational achievement is determined based on at least one of the determined values. | 2015-02-26 |
20150056595 | SYSTEMS AND METHODS FOR DIAGNOSIS AND TREATMENT OF PSYCHIATRIC DISORDERS - A device for diagnosing and treating psychiatric disorders is described. The device may be configured to provide a graphical user interface that enables a user to select at least one of: entering information related to a diagnosis of the psychiatric disorder and alleviating symptoms caused by the psychiatric disorder. Upon a user selecting entering information related to the diagnosis of a psychiatric disorder, the device may receive information related to the diagnosis of the psychiatric disorder. The device may determine the severity of a user's condition based at least in part on the received information. The device may provide a treatment based on the determined severity of the user's condition. A treatment may include providing feedback to a user. | 2015-02-26 |
20150056596 | Automated Course Deconstruction into Learning Units in Digital Education Platforms - An educational course is automatically deconstructed into discrete learning units. Content related to the course that has been stored by an integrated education platform is analyzed, and distinct concepts are extracted from the content. In addition, the learning activities in which users engage while accessing integrated learning services from the platform are recorded. These activities can generally be divided into passive, active, and recall activities. By deconstructing educational courses into individual concepts, a general model of learning is then applied that connects concepts to the activities undertaken by students to learn those concepts. As a result, a model of learning is developed where courses are atomized into individual learning units, each of which comprises a concept and at least one learning activity. The learning units then can be delivered independently or aggregated as desired. | 2015-02-26 |
20150056597 | SYSTEM AND METHOD FACILITATING ADAPTIVE LEARNING BASED ON USER BEHAVIORAL PROFILES - Methods and systems for adaptively assigning a questionnaire to a user are disclosed. In one embodiment, a transactional data and log data associated with activities performed by each user of a plurality of users may be captured. The transactional data and the log data may be analyzed to retrieve a first set of parameters and a second set of parameters. A profile for each user of the plurality of users may be generated by analyzing the first set of parameters. A complexity index value of each questionnaire of the plurality of questionnaires may be determined by analyzing the second set of parameters. The profile of each user of the plurality of users may be matched with the complexity index value of each questionnaire of the plurality of questionnaires. Based upon the matching, at least one questionnaire from the plurality of questionnaires may be assigned to the user. | 2015-02-26 |
20150056598 | SYSTEM AND METHOD FOR DISPLAYING USER-SPECIFIC CONTENT ON AN E-LEARNING PLATFORM - The present disclosure described herein, generally relates to a system and method for displaying user-specific content on an online learning platform. In one aspect, a method and system are disclosed for displaying user-specific content retrieved from an internet to the user, based on user's requirement. Based on the interaction of the user with the learning platform, a user-profile may be generated and further categorized into a pre-defined learning category. Along with the user-profile, the system may be also configured to generate a profile of content fetched from the online library of the learning platform on basis of pre-defined parameters. From the content profiled, phrases may be extracted for generating search strings. These search strings may be further used to perform an automated search over the internet to retrieve the user-specific content. Further, the user-specific content may be also profiled on basis of the pre-defined parameters. The user-specific content may be evaluated against the content fetched to evaluate and assign a score to the user-specific content. Based on the score assigned, the user-specific content may be displayed to the user. | 2015-02-26 |
20150056599 | WRITE ERASABLE COMPONENT SYSTEM - A series of devices that allow for embedding of an image as a background while also affording the user the ability to write and print on the surface, with erasable capabilities, thus providing a multifunctional product for use in numerous industries. The devices are manufactured from predominately corrugated plastic. In one embodiment a one piece, removably attachable, cabinet system and graphic display system. In an additional embodiment, a writable board, or peg board comprising a front panel and a rear panel wherein the panels are interconnected by parallel rows, or corrugations, these panels include a writable and erasable surface. The present invention relates to assemblies of corrugated systems to better serve personal, business, and educational needs. | 2015-02-26 |
20150056600 | CONFIGURABLE PANEL DISPLAY - A configurable panel display includes panel frames configurable to support respective panels, adjacent ones of the panel frames being pivotably connected along opposing edges, each panel frame having intersecting sides formed by tubular frame members, and a cap hinge assembly pivotably connecting two adjacent ones of the panel frames. Each cap hinge assembly includes two frame corner pieces, each frame corner piece interconnecting tubular frame members of two intersecting sides of a respective one of the adjacent ones of the panel frames. Each frame corner piece includes projections received within the interconnected tubular frame members, a central corner piece body from which each of the projections integrally extends, a hinge cap spanning the two frame corner pieces, and two fastening members, each fastening member connecting the hinge cap to a respective one of the frame corner pieces. | 2015-02-26 |
20150056601 | Cardiopulmonary Apparatus and Methods for Preserving Organ Viability - Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the viability or one or more organs in a clinically dead organ donor or harvested donor organ for subsequent transplantation to an organ receiver patient. | 2015-02-26 |
20150056602 | APHERESIS PLATELETS WITH FIXED RESIDUAL PLASMA VOLUME - Methods and systems for obtaining platelets are disclosed. Platelets are collected in a pre-determined volume of plasma and a determined amount of a combined storage medium including the pre-determined amount of plasma and a volume of a synthetic additive solution. | 2015-02-26 |
20150056603 | METHOD AND APPARATUS FOR HARVESTING AND DISPENSING A FIBRIN CLOT - Apparatus for extracting fibrin from blood so as to form a fibrin clot, the apparatus comprising:
| 2015-02-26 |
20150056604 | COMPOSITIONS AND METHODS FOR PRESERVING PLATELET FUNCTION - Compositions and methods for maintaining platelet functionality and extending the shelf-life of platelets are described. Platelet preservation compositions include a photosensitizer and a plurality of platelet preservation agents. A method for preserving platelets and extending their shelf-life includes irradiating a platelet mixture containing a photosensitizer under conditions sufficient to activate the photosensitizer and inactivate microbes in the platelet mixture to form a microbe-depleted platelet preparation. A plurality of platelet preservation agents are added to the microbe-depleted platelet preparation for extending the platelet shelf-life. Prior to transfusion, the photosensitizer and platelet preservation agents can be removed by diafiltration and/or the use of compound adsorption devices. | 2015-02-26 |
20150056605 | IDENTIFICATION OF BLOOD BASED METABOLITE BIOMARKERS OF PANCREATIC CANCER - The present disclosure relates to a panel of a plurality of metabolite species that is useful for the identification or detection of subjects having pancreatic cancer, including methods for identifying such metabolic biomarkers within biological samples. The disclosure also includes a statistical model for predicting the presence of pancreatic cancer in a subject's biofluid by quantifying and comparing positive and negative fold changes in metabolite species' concentration; comparing the subject's metabolite species' concentrations to a predetermined value. | 2015-02-26 |
20150056606 | TISSUE TESTER - A tissue tester for providing an indication of the presence of disease including a first paper tissue sheet; and a filter patch treated with a color changing indicator affixed to the first paper tissue sheet. The tester may also consist of a single sheet of filter paper treated with a solution of turmeric and alcohol. The color indicator changes from yellow to brown when disease is indicated in respiratory secretions. | 2015-02-26 |
20150056607 | FLOW CYTOMETER WITH DIGITAL HOLOGRAPHIC MICROSCOPE - The current invention concerns a flow cytometric system and method for observing, analyzing and/or separating objects in a liquid sample, comprising a digital holographic microscope (DHM) and at least one fluidic system, whereby the DHM comprises illumination means, an interferometric system and digital recording means, whereby the fluidic system is capable of guiding said objects through an illumination beam of the illumination means of said DHM, whereby the fluidic system comprises a mechanism for inducing a liquid sample stream through the fluidic system, whereby preferably the fluidic system comprises a stream size controlling device for controlling the transverse dimensions of a liquid sample stream inside said fluidic system, preferably said stream size controlling device is capable of lining up the objects one-by-one or multiple objects at a time in said liquid sample stream. | 2015-02-26 |
20150056608 | Method for Treating Infectious Diseases Using Emissive Energy - The present invention relates to the treatment of infectious diseases, specifically by extracorporeally eradicating the pathogen. This invention comprises methods for the extracorporeal treatment of infectious diseases that will remove infectious pathogens (leukemia cells, bacteria, viruses, or fungi causing a septicemia, metastatic cancer cells, target protein, viruses, parasites, fungi and prions) in humans by targeting such pathogens with a laser or other high-energy source of emissive radiation. More specifically, the method involves removing a bodily fluid from a patient, attaching an antibody to pathogens in the bodily fluid, sensing the antibody-pathogen moiety, using a high-powered, focused laser to destroy the antibody-pathogen moiety, removing the remains of the antibody-pathogen by filtering or other suitable mechanism(s), and returning the bodily fluid to the patient. | 2015-02-26 |
20150056609 | Next Generation Genomic Sequencing Methods - Disclosed is an enhanced method for rapid and cost-effective analysis of sequences of a microorganism by semi-conductor sequencing, preferably ion-torrent sequencing. This method provides for full length analysis and of multiple areas (e.g. genes) of multiple genomes. These methods identify genetic mutations of a particular gene that are responsible for conferring resistance or sensitivity to an antibiotic or other chemical compound. Multiple different species, strains and/or serotypes of a particular organism are rapidly and efficiently screened and mutations identified along with the complete genome of an organism. By selecting primers pairs of similar size and GC content that produce amplicons with sequences spanning the entire genome, a single PCR reaction analyzed by ion torrent methodology can determine the sequence of a complete genome. Methods are useful to sequences the genomes of viral agents, such as influenza virus, and bacterial agents, such as tuberculosis bacteria. | 2015-02-26 |
20150056610 | MONITORING AND INHIBITING HUMAN IMMUNODEFICIENCY VIRUS INFECTION BY MODULATING HMGB1 DEPENDENT TRIGGERING OF HIV-1 REPLICATION AND PERSISTENCE - Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample. | 2015-02-26 |
20150056611 | Method for Manipulating Magnetic Particles in a Liquid Medium - A method of mixing magnetic particles ( | 2015-02-26 |
20150056612 | METHODS FOR TARGETING RNA MOLECULES - Described are methods for identifying targets in RNA molecules based on differences in RNA secondary structure related to sequence variances between different allelic forms. Also described are methods for identifying or developing small molecules which can be used to modulate a target RNA by creation of protein-small-molecule-RNA complexes, as well as compositions which include such small molecules and methods of using those small molecules and compositions. | 2015-02-26 |
20150056613 | METHODS AND SYSTEMS FOR DETECTING SEQUENCE VARIANTS - The invention provides methods for identifying rare variants near a structural variation in a genetic sequence, for example, in a nucleic acid sample taken from a subject. The invention additionally includes methods for aligning reads (e.g., nucleic acid reads) to a reference sequence construct accounting for the structural variation, methods for building a reference sequence construct accounting for the structural variation or the structural variation and the rare variant, and systems that use the alignment methods to identify rare variants. The method is scalable, and can be used to align millions of reads to a construct thousands of bases long, or longer. | 2015-02-26 |
20150056614 | DEVICES AND METHODS OF CELL CAPTURE AND ANALYSIS - The present invention provides a device for isolating target biomolecules or cells from samples, particularly biological samples. In particular, the device comprises a loading mixture, which contains the biological sample and a first binding entity that specifically binds to the target biomolecule or target cell; and a micro-channel coated with a second binding entity that binds directly or indirectly to the first binding entity. Methods of capturing, detecting, and/or evaluating target biomolecules or target cells (e.g. cancer cells) in biological samples are also disclosed. | 2015-02-26 |
20150056615 | ISOLATION OF FACTORS THAT ASSOCIATE DIRECTLY OR INDIRECTLY WITH NON-CODING RNAS - Methods and assays are provided for isolating factors including polypeptides, ribonucleic acids (RNAs) and polypeptide complexes that are associated with a target nucleic acid sequence. The target nucleic acid sequence may be comprised within chromatin. The methods are suitable for identification and characterisation of factors including non-coding RNAs (ncRNAs) that associate with specified genomic loci. | 2015-02-26 |
20150056616 | COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-HYDROXYMETHYLCYTOSINE (5-hmC) - The present invention relates generally to the field of molecular biology. More particularly, it concerns methods and compositions for detecting, evaluating, and/or mapping 5-hydroxymethyl-modified cytosine bases within a nucleic acid molecule. | 2015-02-26 |
20150056617 | METHODS AND COMPOSITIONS FOR ANALYZING AHASL GENES IN WHEAT - The present disclosure provides methods, kits, and primers for analyzing AHASL genes of plants, including wheat. The methods, kits, and primers of the present disclosure can make use of forward AHASL primers designed without use of software or other assay-design technology and can be used in a real-time PCR assay to determine the zygosity of AHASL genes encoding AHAS enzymes providing tolerance to AHAS enzyme inhibitors. | 2015-02-26 |
20150056618 | METHOD AND APPARATUS - A method for mapping the number and location of restriction enzymes sites for a given restriction enzyme in a target nucleic acid comprises the steps of (1) translocating a target nucleic acid having detectable elements characteristic of the presence of the restriction enzyme sites therein through an analysing device comprising a nanopore and a detection window and (2) causing the detectable elements to be detected as they pass though the detection window. Typically the detectable elements are formed by attaching to the restriction enzyme sites a restriction enzyme to which one or more marker moieties have been added. The data or signal obtained from the detection is suitably in the form of a distribution profile of the detectable elements, and therefore the restriction enzyme sites along the length of the target nucleic acid and can be used to create a reference set of like distribution profiles against which new distributions can be compared. When the target nucleic acid is for example double stranded human DNA such comparisons enable valuable insights to be drawn about an individual's identity or his or her susceptibility to certain health conditions. | 2015-02-26 |
20150056619 | METHOD AND SYSTEM FOR DETERMINING COPY NUMBER VARIATION - Disclosed are a method and a system for determining genome copy number variation, which relates to the technical field of bioinformatics. The method comprises obtaining reads; determining sequence labels according to the reads; counting the number of sequence labels falling into each window; performing GC correction on the sequence label number of each window and a correction according to an expected sequence label number adjusted by a control set to obtain a corrected sequence label number; selecting a demarcation point with a small significance value as a candidate CNV breaking point; rejecting the least significant candidate CNV breaking point at every turn, updating difference significance values of two candidate CNV breaking points on the left and right of the rejected candidate CNV breaking point and performing cyclic iteration until difference significance values of all candidate CNV breaking points are smaller than a termination threshold value, thereby determining a CNV breaking point. The method and the system the present invention have clinical feasibility, and can precisely detect a micro-deletion/micro-duplication area of 0.5 M under the situation of using data of about 50 M. | 2015-02-26 |
20150056620 | METHODS FOR RAPID IDENTIFICATION OF PATHOGENS IN HUMANS AND ANIMALS - The present invention provides methods of: identifying pathogens in biological samples from humans and animals, resolving a plurality of etiologic agents present in samples obtained from humans and animals, determining detailed genetic information about such pathogens or etiologic agents, and rapid detection and identification of bioagents from environmental, clinical or other samples. | 2015-02-26 |
20150056621 | PRIMERS, METHODS AND KITS FOR DETECTING KILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR ALLELES - Embodiments of the present invention describe primer pairs, methods and kits for identifying and/or detecting killer-cell immunoglobulin-like receptor (KIR) alleles. The present primer sets include one or more primer pairs that can produce amplicons specific for an individual KIR allele and that are less than 1000 bp in size. Additionally, the primer sets can target intra-exon and/or extracellular domains of KIR alleles for amplification. | 2015-02-26 |
20150056622 | EDITING PROFILING OF PDE8A PRE -MRNA: USE AS SPECIFIC BIOMARKER OF ADARS ACTIVITIES IN HUMAN TISSUES TO DIAGNOSE AND TO PREDICT AND ASSESS THERAPEUTIC EFFICACY AND/OR EFFICIENCY OR POTENTIAL DRUG SIDE EFFECTS - The present invention relates to the use of the editing profile of PDE8A pre-mRNA as a specific bio marker of ADARs activities in evolved primate, particularly in Human tissues. The present invention also relates to an in vitro method for predicting in Human an alteration of the mechanism of the ADARs catalysed pre-mRNA editing of target genes, by analysing the PDE8A pre-mRNA editing profile in a peripheral tissue sample containing cells expressing said PDE8A pre-mRNA, such as blood sample. The present invention is also directed to an in vitro method for the screening of potential therapeutic compound and to predict and assess therapeutic efficacy and/or efficiency or to diagnose potential severe brain or peripheral drug side effects implementing said PDE8A pre-mRNA editing profile as specific biomarker. The present invention is further directed to a method for determining the PDE8A pre-mRNA editing profile in Human, particularly by capillary electrophoresis single-strand conformation polymorphism (CE-SSCP) method after amplification by a nested PCR. Finally the invention relates to particular nucleic acid primers implemented in said nested PCR and kit comprising such sets of primers and human cells capable of expressing PDE8A and ADARs. | 2015-02-26 |
20150056623 | Oligonucleotide Primer with Omega Structure for Detecting Short-Chain RNAs and Use Thereof - Disclosed are an oligonucleotide primer with an omega structure for detecting short-chain RNAs and the use thereof. The primer from the 5′ end to the 3′ end sequentially is: a PCR primer target region of 20-30 bases, a variable coding region of 0-50 bases, an omega stem-loop, a probe spacer of at least one base and a probe region of 4-11 bases. The length of the stem of the omega stem-loop is 4-12 paired bases, and the length of the loop of the omega stem-loop is 3-20 unpaired bases. | 2015-02-26 |
20150056624 | METHOD FOR ISOLATING NUCLEIC ACIDS FROM A FOOD SAMPLE - The method for isolating nucleic acids from a food sample comprising the following steps: a) obtaining a food enrichment culture; b) transferring a portion of the food enrichment culture into a reaction vessel thereby providing a food enrichment sample and providing a water-immiscible phase in contact with the food enrichment culture; c) lysing the food enrichment sample to provide a lysed sample; d) isolating nucleic acids from the lysed sample. Food enrichment culture samples are known to contain high concentrations of organic and/or liposoluble inhibitors. By contacting the enrichment culture sample with a water-immiscible phase before the actual DNA extraction procedure starts, part of the lipophilic inhibitors is expected to cross the phase interface due to an enhanced solubility in the organic phase and thereby become depleted. The water-immiscible phase provided according to the invention interacts directly with the sample material throughout bacteria lysis and DNA extraction thereby optimizing the subsequent DNA purification processes due to the depletion of food-borne inhibitors. This method yields nucleic acids, in particular DNA that is of an improved quality and purity to be used in a subsequent PCR reaction to detect pathogen nucleic acids in the isolated nucleic acids. | 2015-02-26 |
20150056625 | REAGENT FOR CLARIFYING EMULSIONS AND METHOD OF CLARIFICATION - A novel reagent for clarification of an emulsion containing a salt and first and second surfactants is used in a method of clarifying emulsions which may contain inorganic, organic or biological particles to be measured. The reagent may be proved as kit of parts for in situ preparation thereof. | 2015-02-26 |
20150056626 | NUCLEIC ACID AMPLIFICATION KITS FOR SPECIFIC DETECTION OF E. COLI O157:H7 WITHOUT CO-DETECTION OF E. COLI O55:H7 - Disclosed are assays, methods and kits for the specific detection of | 2015-02-26 |
20150056627 | APTAMERS - A nucleic acid aptamer comprising the nucleotide sequence shown herein as SEQ ID No. 5, 6, 7, 8, 9, 10, 1, 2, 3 or 4 or a fragment thereof or a sequence which is at least 80% identical therewith and use of nucleic aptamers to detect the presence of pathogenic bacteria in a sample, particularly in a complex matrix—such as a food system. | 2015-02-26 |
20150056628 | DETECTION AND TYPING OF BACTERIAL STRAINS - Methods for the detection and typing of bacterial strains from food products and dietary supplements, environmental samples, in vivo/in vitro samples, and for studying the natural diversity of the species are disclosed. Potential applications also include product development and/or detection and differentiation of new bacterial strains. | 2015-02-26 |
20150056629 | Compositions, systems, and methods for detecting a DNA sequence - Provided are compositions, systems, and methods that employ one or more fusion protein pairs, wherein each fusion protein within a fusion protein pair comprises a sequence-specific nucleic acid binding protein, such as sequence-specific Cas9 protein (e.g., a CRISPR), a sequence specific transcription activator-like enhancer (“TALE”) protein, a sequence specific homing endonuclease (“HE”; a/k/a meganuclease), a three prime exonuclease (“TREX”), and/or a sequence specific zinc finger (“ZF”) protein, which sequence-specific nucleic acid binding protein is operably linked to one half of a split-reporter molecule, such as a split-fluorescent reporter molecule, a split-luminescent reporter molecule, a Förster resonance energy transfer (FRET) reporter molecule, or a Bioluminescence Resonance Energy Transfer (BRET) reporter molecule. | 2015-02-26 |
20150056630 | DNA CONTROLLING MIR-140 EXPRESSION, AND SCREENING METHOD OF DRUGS USING SAID DNA - An object of the present invention is to provide DNA which regulates the expression of miR-140, a reporter vector which contains the DNA, cells and animals into which the reporter vector is introduced and a screening system for drugs which control the expression of miR-140 and is also to contribute in the development of new therapeutic agents for cartilage diseases such as osteoarthritis and intervertebral disk degeneration using the screening system. The DNA sequence according to the present invention is able to express any gene in a site where miR-140 is expressed and, in addition, it is also able to be utilized for screening a drug which regulates the expression of miR-140. Moreover, the drug that is selected by the screening system of the present invention is expected as a therapeutic agent for cartilage diseases accompanied by abnormality of cartilage. | 2015-02-26 |
20150056631 | Methods and Compositions for Diagnosing Disease - The present invention relates to methods and compositions for diagnosing a disease or disorder in a subject by introducing into cells of the subject a diagnostic gene switch construct and monitoring expression of a reporter gene. The invention further relates to methods and compositions for monitoring the progression of a disease or disorder or the effectiveness of a treatment for a disease or disorder. | 2015-02-26 |
20150056632 | FLUORESCENT DYES, FLUORESCENT DYE KITS, AND METHODS OF PREPARING LABELED MOLECULES - The present invention provides methods, compositions, and kits useful in preparing labeled molecules, which are useful in the detection of binding partners. | 2015-02-26 |
20150056633 | DETECTION OF GLUTATHIONYLATED PROTEINS - The present invention, in some aspects, relates to systems and methods for determining oxidized proteins, including glutathionylated proteins such as S-glutathionylated proteins. The systems and methods of the invention can be used in vitro (e.g., in cell or tissue culture) or in vivo, for example, to diagnose a person having an oxidative stress condition. For instance, in some cases, the invention can be used to spatially determine the location and/or concentration of oxidized proteins within cells and/or tissues (e.g., through visual detection). In one set of embodiments, a glutathionylated or otherwise oxidized moiety on a protein may be reacted with a detection entity, which may be, for example, fluorescent, radioactive, electron-dense, able to bind to a signaling entity or a binding partner in order to produce a signal, etc. As a specific example, a glutathionylated moiety on a glutathionylated protein may be reacted with an alkylating agent to form an alkylthio moiety; the alkylthio moiety may include a detection entity or otherwise be able to interact with a signaling entity. In some embodiments, other moieties on the protein may be altered or blocked before reaction of the protein with the detection entity. Such moieties on the protein may be, for instance, non-oxidized or non-glutathionylated moieties able to react with the detection entity. As a particular example, in a protein containing a glutathionylated moiety and non-glutathionylated thiol moieties, the thiol moieties may first be altered or blocked prior to reaction of the protein with the detection entity. Also provided in certain aspects of the present invention are kits for determining oxidized proteins, which may include components such as detection entities, alkylating agents, blocking agents, reducing agents, signaling entities, binding partners, antibodies, instructions, and the like. | 2015-02-26 |
20150056634 | Methods for Preparing Dry Formulations of Glucose Binding Protein - Methods and compositions for preparing dry formulations of Glucose Binding Proteins (GBPs) are disclosed. The GBPs may be stored as a dry formulation without significant loss of activity. After reconstitution, the GBPs may be used to determine the glucose concentration of a sample. | 2015-02-26 |
20150056635 | Systems and Methods for Anti-PAX8 Antibodies - The present invention is related to the anti-PAX8 antibodies, kits, cocktails, and use of anti-PAX8 antibodies for detection of cancer. | 2015-02-26 |
20150056636 | Transgenic Immunodeficient Mouse Expressing Human SIRP-alpha - The present invention provides a transgenic mouse which comprises a deficiency for murine T lymphocytes, B lymphocytes and NK cells, a deficiency for murine MHC class I and MHC class II molecules, and a functional xenogenic SIRPα transgene. This mouse is useful for in vivo screening of various compounds, including immuno-therapeutic agents and vaccines. The said mouse is also useful for testing the in vivo metabolism of xenobiotic compounds. | 2015-02-26 |
20150056637 | FECAL SAMPLING DEVICE AND METHOD - A collection device for use in connection with off-device testing of collected samples. The device includes a first panel having one or more apertures for receiving samples, a second panel opposite the first panel, and a removable tab having a first portion and a second portion. The first portion is aligned with at least one of apertures on the first panel and constructed such that depositing the sample through the at least one aperture causes the sample to be directly deposited on the first portion of the tab, and the second portion includes a sample-free grasping area accessible from an exterior of the device for removing the tab. A method of obtaining a sample is also disclosed. | 2015-02-26 |
20150056638 | NANOSCALE PROCESS TO GENERATE REAGENTS SELECTIVE FOR INDIVIDUAL PROTEIN VARIANTS - The present invention provides devices and methods to separate and concentrate target protein species at a microliter scale and to generate reagents to those variants with exquisite selectivity for specific protein isoforms using only picograms of target material. | 2015-02-26 |
20150056639 | DETECTING COMPLEMENT ACTIVATION - Methods of detecting complement activation including steps of detecting in a sample from a subject a level of iC3b wherein the detecting involves specific interaction between the iC3b and a non-cross-reactive antibody thereto, comparing the detected level with a reference level, which reference level is within a range of about 10 ng/ml to about 5,000 ng/ml, wherein determination that the detected level is above the reference level indicates that the subject is suffering from or susceptible to undesirable and/or pathologic complement activation, and administering treatment to treat undesired complement activation if the detected level is above the reference level. Other methods of detecting complement activation with or without measuring iC3b are also provided. | 2015-02-26 |
20150056640 | REAGENTS AND METHODS FOR DETECTING A POLYMORPHIC PROTEIN - The present invention provides antibodies that differentially react with allelic variants of a polymorphic protein, methods of identifying same, an antigen binding fragment comprised therein, proteins, cells, viral particles, compositions, and kits comprising same. The invention also provides methods for determining a haptoglobin type of a subject and methods for testing a subject for susceptibility to diabetic complications. | 2015-02-26 |
20150056641 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Trefoil factor 3 as diagnostic and prognostic biomarker assays in renal injuries. | 2015-02-26 |
20150056642 | ARMET AS A MARKER FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) - An in vitro method aiding in the assessment of chronic obstructive pulmonary disease (COPD). The disclosure further relates to a method for assessing COPD from a sample, derived from an individual, by measuring the protein ARMET in said sample in vitro. | 2015-02-26 |
20150056643 | MICROFLUIDIC DEVICES FOR MEASURING PLATELET COAGULATION AND ASSOCIATED SYSTEMS AND METHODS - The present technology relates generally to microfluidic devices for measuring platelet coagulation, and associated systems and methods. In some embodiments, a fluidics device includes an array of microstructures including pairs of generally rigid blocks and generally flexible posts. The fluidics device further includes at least one fluid channel configured to accept the array. The fluid channel is configured to induce fluid flow of a biological sample, such as whole blood, through the array. The fluidics device can further include a detection component configured to measure a degree of deflection of one or more of the flexible posts in the array. In some embodiments, the fluidics device comprises a handheld device and usable for point of care testing of platelet forces and coagulation. | 2015-02-26 |
20150056644 | CONTINUOUS CULTURE APPARATUS WITH MOBILE VESSEL, ALLOWING SELECTION OF FITTER CELL VARIANTS AND PRODUCING A CULTURE IN A CONTINUOUS MANNER - A method and device for growing plant, animal or stem cells in a continuous manner. | 2015-02-26 |
20150056645 | METHODS AND APPARATUSES FOR LABEL-FREE PARTICLE ANALYSIS - An apparatus to provide a label-free or native particle analysis comprises a light generating system producing first light pulses at a first wavelength and second light pulses at a second wavelength; and a flow cell coupled to the light generating system to convey particles for analysis. The light generating system is configured to chirp at least one of the first light pulses and the second light pulses to analyze the particles. | 2015-02-26 |
20150056646 | CYANOCHROME FLUOROPHORES - Genetically-engineered cyanochrome fluorophore molecules (fluorophores) with increased fluorescence and with absorbing fluorescence in the blue and green (blue/green) portion of the light spectrum are provided. These fluorophores are derived from the domains of phytochromes, and in particular cyanobacterial phytochromes. Methods for generating these fluorophores and various applications of these fluorophores are also provided. | 2015-02-26 |
20150056647 | METHOD OF DIFFERENTIATING MAMMALIAN PROGENITOR CELLS INTO INSULIN PRODUCING PANCREATIC ISLET CELLS - The invention relates to methods for differentiating progenitor cells into insulin producing pancreatic islet cells and compositions and methods for using such cells. | 2015-02-26 |
20150056648 | METHODS OF DETERMINING BIOCIDE EFFICACY OR MECHANISM OF ACTION USING FLOW CYTOMETRY - Disclosed are methods of determining biocide efficacy using flow cytometry. The methods can be used to determine the synergy between at least two biocides. | 2015-02-26 |
20150056649 | METHOD FOR QUANTIFYING CELL OF INTEREST IN BLOOD, AND METHOD FOR EVALUATING SYSTEM FOR QUANTIFYING SAID CELL - A method for quantifying cells of interest potentially contained in a blood-derived sample in cases of their quantification after separation from the blood-derived sample may enable accurate quantification of the cells without causing underestimation of the cell number. The quantification method is a method for quantifying specific cells of interest, the method may include: (A) separating a blood-derived sample containing a known number (P0) of specific resin particles P into at least two layers including a layer of erythrocytes and a layer of cells other than erythrocytes; (B) extracting the layer of cells other than erythrocytes and counting the number of cells of interest and the number (P1) of the resin particles therein; and (C) correcting the number of cells of interest by multiplying the number of cells of interest by P0/P1. | 2015-02-26 |
20150056650 | MICROFLUIDIC APPARATUS, METHOD, AND APPLICATIONS - A microfluidic apparatus, method, and associated applications utilize and apply to a formalin-fixed paraffin-embedded (FFPE) tissue sample and performing a liquid-liquid extraction to remove the paraffin from the tissue sample prior to a nucleic acid purification step. A microfluidic device includes a dedicated liquid-liquid extraction process vessel, a nucleic acid purification process component, and a nucleic acid amplification reactor. A liquid-liquid extraction and nucleic acid purification kit includes a microfluidic device capable of performing both a liquid-liquid extraction process and a nucleic acid purification process, including a dedicated liquid-liquid extraction process vessel, an immiscible liquid or a precursor phase thereof disposed in the vessel, a nucleic acid purification process component, a nucleic acid amplification reactor fluidically, and a supply of reagents suitable to enable the liquid-liquid extraction process and the nucleic acid purification process. | 2015-02-26 |
20150056651 | MICROORGANISM PRODUCTION OF HIGH-VALUE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes polyketides and 3-hydroxypropionic acid. | 2015-02-26 |
20150056652 | Methods For Increasing Homologous Recombination Of A Nucleic Acid Sequence - The present invention relates to methods for increasing homologous recombination of a nucleic acid sequence introduced into a host cell, comprising: (a) introducing into a population of filamentous fungal host cells a first nucleic acid sequence encoding a recombination protein and a second nucleic acid sequence comprising one or more regions which are homologous with the genome of the filamentous fungal host cell, wherein (i) the recombination protein promotes the recombination of the one or more regions with the corresponding homologous region in the host's genome to incorporate the second nucleic acid sequence by homologous recombination, and (ii) the number of host cells comprising the incorporated second nucleic acid sequence in the population is increased at least 20% compared to the same population without the first nucleic acid sequence; (b) and isolating from the population a filamentous fungal cell comprising the incorporated second nucleic acid sequence. | 2015-02-26 |
20150056653 | PROTEIN PRODUCTION METHOD - Provided herein are methods of producing a heterologous polypeptide and compositions comprising same. | 2015-02-26 |
20150056654 | PROCESS FOR THE PURIFICATION OF RECOMBINANT ALBUMIN - A process is provided for the preparation of a highly pure albumin solution the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. Preferably, the process comprises the steps of positive mode cation exchange chromatography, positive mode anion exchange chromatography, positive mode affinity chromatography, negative mode affinity chromatography (preferably using immobilised aminophenylboronic acid), negative mode cation exchange chromatography, and negative or positive mode anion exchange chromatography. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons. Also disclosed is a process for producing recombinant albumin, the process comprising culturing a fungal cell expressing a recombinant albumin coding sequence, wherein the cell has a reduced capacity of mannosylation of the recombinantly-expressed albumin. | 2015-02-26 |
20150056655 | EXPRESSION CONSTRUCTS AND METHODS FOR EXPRESSING POLYPEPTIDES IN EUKARYOTIC CELLS - The invention relates to an expression construct for the expression of polypeptides in host cells using alternative splicing. The expression construct can be used for the expression of polypeptides such as antibodies, antibody fragments and bispecific antibodies by expressing the gene products required for protein expression at the ratio leading to the highest titres or the best product quality profile. | 2015-02-26 |