09th week of 2014 patent applcation highlights part 41 |
Patent application number | Title | Published |
20140057310 | Label Free Biosensors And Cells - Disclosed are compositions and methods for using label free optical biosensors for performing cell assays. In certain embodiments the assays can be performed in high throughput methods and can be multiplexed. | 2014-02-27 |
20140057311 | Device For High Throughput Investigations Of Multi-Cellular Interactions - Provided herein are microfluidic devices that can be used as a 3D bioassay, e.g., for drug screening, personalized medicine, tissue engineering, wound healing, and other applications. The device has a series of channels {e.g., small fluid channels) in a small polymer block wherein one or more of the channels can be filled with a biologically relevant gel, such as collagen, which is held in place by posts. As shown herein, when the device is plated with cells such as endothelial cells, new blood vessels grow in the gel, which is thick enough for the cells to grow in three dimensions. Other channels, e.g., fluid channels, allow drugs or biological material to be exposed to the 3D cell growth. Cells, such as endothelial cells, can be cultured and observed as they grow on the surface of a 3D gel scaffold, where e.g., rates of angiogenesis can be measured, as well as intervascularization and extravascularization of cancerous cells. | 2014-02-27 |
20140057312 | FLUORESCENT PROBE - A compound represented by the formula (I) (one of substituents represented by R | 2014-02-27 |
20140057313 | Methods for Making Cells with an Extra-Embryonic Endodermal Precursor Phenotype - The invention is directed to methods for making cells in vitro that have an extra-embryonic endodermal precursor phenotype. The method involves culturing cells from blastocysts under specific defined conditions. | 2014-02-27 |
20140057314 | METHODS AND COMPOSITIONS FOR DETECTING MICROBIAL PRODUCTION OF WATER-IMMISCIBLE COMPOUNDS - Provided herein are methods and compositions useful for detecting the production of compounds in a cell, for example, a microbial cell genetically modified to produce one or more such compounds at greater yield and/or with increased persistence compared to a parent microbial cell that is not genetically modified. In some embodiments, the methods comprise contacting a solution with a fluorescent dye that directly binds the recombinantly produced compound, wherein the solution comprises a plurality of cells recombinantly producing the compound; and detecting the fluorescent dye under spectral conditions suitable for the selective detection of the fluorescent dye bound to the recombinantly produced compound. | 2014-02-27 |
20140057315 | ANTIGEN PRESENTING CELL ASSAY - Disclosed herein are methods for diagnosing or predicting acute cellular and/or humoral rejection in a subject. In one example, a method of assessing organ rejection includes contacting a first sample comprising antigen presenting cells (APCs) obtained from a subject in need of or having received an organ transplant with a donor antigen from a donor under conditions sufficient to induce uptake of the donor antigen; contacting a second sample comprising APCs obtained from the subject in need of or having received an organ transplant with a third-party antigen under conditions sufficient to induce uptake of the third-party antigen; and determining an antigen presenting index by determining a ratio of uptake of the donor antigen in the first sample to uptake of the third-party antigen in the second sample, wherein the ratio of greater than one indicates organ rejection and the APCs are monocytes or monocyte-derived cells. | 2014-02-27 |
20140057316 | METHOD OF PRODUCING AND PURIFYING AN ACTIVE SOLUBLE SIALYLTRANSFERASE - The present invention relates to a method for the production and purification of a sialyltransferase polypeptide, in particular a N-Acetylgalactosamine (Gal NAc)-α-2,6-sialyltransferase I (ST6GalNAcI) polypeptide. The method comprises the steps of producing the sialyltransferase polypeptide in a Chinese Hamster Ovary (CHO) cell and purifying the polypeptide with a combination of chromatography steps. The method results in high yield of sialyltransferase polypeptide which is highly pure and active. The obtained sialyltransferase, especially ST6GalNAcI, can be employed for the glycosylation of therapeutic proteins such as G-CSF. | 2014-02-27 |
20140057317 | EVOLUTION OF BOND-FORMING ENZYMES - Strategies, systems, methods, reagents, and kits for the directed evolution of bond-forming enzymes are provided herein. Evolution products, for example, evolved sortases exhibiting enhanced reaction kinetics and/or altered substrate preferences are also provided herein, as are methods for using such evolved bond-forming enzymes. Kits comprising materials, reagents, and cells for carrying out the directed evolution methods described herein are also provided. | 2014-02-27 |
20140057318 | POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCE AND METHODS THEREOF - The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human insulin precursor including leader peptide coding sequence, cloning in an expression vector and expression in an organism, preferably | 2014-02-27 |
20140057319 | Methods and Vectors for Generating Asialylated Immunoglobulins - The properties of an Fc-containing protein, for example, an antibody, are controlled by altering the sialylation of the oligosaccharides in the Fc region by transfecting the cell line expressing the Fc-containing protein with a vector sequence encoding a sialidase. The modified Fc-containing proteins have therapeutic utility in diseases or conditions in which it is desirable to control the affinity for one or more of the FcγRI, FcγRIIA, and FcγRIIIA receptors, ADCC activity, macrophage or monocyte activation, serum half-life, and avidity. | 2014-02-27 |
20140057320 | Method for Preparing Cyclic Lipopeptide Compound - Provided is a method for preparing a compound represented by Formula I or a salt thereof, wherein | 2014-02-27 |
20140057321 | METHOD FOR REDUCING GREENHOUSE GASES - The present invention provides a method of reducing greenhouse gases by capturing and storing carbon dioxide in the form of a biomass, which may be converted into a high value material such as, for example, an oil having more than 37% of omega-3, biodiesel, phospholipid, glycerin, glucose, and a protein feed. | 2014-02-27 |
20140057322 | METHOD OF AMPLIFYING DNA FROM RNA IN A SAMPLE - A method of amplifying RNA in a sample and a method of amplifying a pool of RNA is provided. Gene loss and amplification bias may be reduced using the methods. Also, directionality may be preserved in the amplified RNA. The methods may be applied in sequence analysis as well as in general molecular diagnostic areas. | 2014-02-27 |
20140057323 | ENHANCED CELLODEXTRIN METABOLISM - The present disclosure relates to host cells containing two or more of a recombinant cellodextrin transporter, a recombinant cellodextrin phosphorylase, a recombinant β-glucosidase, a recombinant phosphoglucomutase, or a recombinant hexokinase; and to methods of using such cells for degrading cellodextrin, for producing hydrocarbons or hydrocarbon derivatives from cellodextrin, and for reducing ATP consumption during glucose utilization. | 2014-02-27 |
20140057324 | Variants of An Alpha-Amylase With Improved Production Levels in Fermentation Processes - Variants of | 2014-02-27 |
20140057325 | Microbial Conversion of Glucose to Styrene and Its Derivatives - A method for the in vivo production of styrene from renewable substrates using a recombinant microorganism is disclosed. Additionally, a method for the in vivo production of styrene oxide from renewable substrates using a recombinant microorganism is also disclosed. In both cases, the host cell expresses at least one gene encoding a polypeptide that possesses phenylalanine ammonia lyase activity in addition to at least one gene encoding a polypeptide that possesses trans-cinnamic acid decarboxylase activity. In the case of styrene oxide, the host cell must additionally express at least one gene encoding a polypeptide that possesses styrene monooxygenase activity. | 2014-02-27 |
20140057326 | MICROORGANISM PRODUCING HIGH-MOLECULAR-WEIGHT PHA - The present invention provides a microorganism that synthesizes a high-molecular-weight PHA, and a method for producing a high-molecular-weight PHA, which have a productivity of at least 100 g/L. The provision is achieved by controlling the specific activity of a PHA synthase in cells of a microorganism that belongs to the genus | 2014-02-27 |
20140057327 | SINGLE VESSEL PRODUCTION OF BUTANOL FROM BIOMASS USING ENGINEERED THERMOPHILIC MICROORGANISMS - The present invention relates to the production of biofuels by utilizing efficient biomass digestion and fermentation by a new thermophilic microorganism generated after fusion of two different bacteria | 2014-02-27 |
20140057328 | YEAST CELL FOR THE PRODUCTION OF TERPENES AND USES THEREOF - The present invention relates to a yeast cell, wherein said cell comprises a functional gene coding for soluble hydroxymethylglutaryl-coenzyme-A (HMG-CoA) reductase; one or more gene(s) coding for steryl acyltransferase(s) in said cell are defective or deleted; and said cell is prototrophic for at least histidine, leucine or uracil. Moreover, the present invention relates to the use of said cell for the production of one or more terpene(s). Further, the present invention relates to methods of generating said cell and the production of one or more terperne(s) and a pharmaceutical or cosmetically composition, a lubricant or transformer oil comprising said terpene(s). | 2014-02-27 |
20140057329 | KETOL-ACID REDUCTOISOMERASE USING NADH - Methods for the evolution of NADPH specific ketol-acid reductoisomerase enzymes to acquire NADH specificity are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from | 2014-02-27 |
20140057330 | KETOREDUCTASE POLYPEPTIDES FOR THE PRODUCTION OF AZETIDINONE - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 2014-02-27 |
20140057331 | FLAVIN-BOUND GLUCOSE DEHYDROGENASES, A METHOD FOR PRODUCING A FLAVIN-BOUND GLUCOSE DEHYDROGENASE, AND YEAST TRANSFORMANT USED FOR THE SAME - A heat-resistant flavin-bound glucose dehydrogenase having a high substrate specificity for D-glucose, an method for producing the same, and a transformant used for the same. A flavin-bound glucose dehydrogenase gene encoding a flavin-bound glucose dehydrogenase derived from | 2014-02-27 |
20140057332 | GLUCO-OLIGOSACCHARIDE OXIDASES FROM ACREMONIUM STRICTUM AND USES THEREOF - This invention provides a description of novel polypeptides and nucleotide sequences having gluco-oligosaccharide oxidase (GOOX) activity. The polypeptides of the invention can be used for enzymatic processes that modify carbohydrates from wood fiber. These polypeptides can be used in the oxidation of C | 2014-02-27 |
20140057333 | NOVEL FRUCTOSYL PEPTIDE OXIDASE - The present invention encompasses:
| 2014-02-27 |
20140057334 | AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT CHOLINE ACETYLTRANSFERASE ACTIVITY - The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect choline acetyltransferase; a method for assaying pesticidal activity of a test substance, which comprises measuring the activity of a choline acetyltransferase in a reaction system in which the choline acetyltransferase contacts with a test substance, and the like. | 2014-02-27 |
20140057335 | CULTURE MEDIUM FOR CELL GROWTH AND TRANSFECTION - The present invention is directed generally to cell culture media useful for introducing macromolecules and compounds (e.g., nucleic acid molecules) into cells (e.g., eukaryotic cells in the presence of said media. Cells containing introduced materials can be further cultured in the media. In particular, the invention allows introduction of nucleic acid molecules (e.g., vectors) into cells (particularly eukaryotic cells) and expression of proteins encoded by the nucleic acid molecules in the cells. The invention obviates the need to change the cell culture medium each time a different procedure is performed with the cells (e.g., culturing cells vs. transfecting cells). The invention thus provides efficient and high throughput methods to transform/transfect culture and cells avoiding the need for multiple manipulations and transfers of cells during transfection and expression studies. | 2014-02-27 |
20140057336 | BIOCONTROL FORMULATION CONTAINING STREPTOMYCES SPP., METHOD FOR PREPARING THE FORMULATION AND RELEVANT USE - The present invention is a method for preparing a biocontrol formulation by the following steps. A | 2014-02-27 |
20140057337 | SYSTEM AND METHOD FOR ELECTROPORATING A SAMPLE - A system and method are described for electroporating a sample that utilizes one or more sets of electrodes that are spaced apart in order to hold a surface tension constrained sample between the electrodes. The first electrode is connected to the lower body of the system while the second electrode is connected to the upper body. Both electrodes are connected to a pulse generator. Each electrode has a sample contact surface such that the first electrode and the second electrode may be positioned to hold a surface tension constrained sample between the two sample contact surfaces and the sample may receive a selected electric pulse. | 2014-02-27 |
20140057338 | Automated Staining and Decolorization of Biological Material - An improved method and apparatus for staining samples of biological material for accurate analysis of the sample. Biological material is applied to a substrate, such as a microscope slide. The biological specimen is then stained with a selected staining composition, which may be gentian violet for a Gram's Stain analysis. The stained biological material is at least partially decolorized and the level of decolorization is analyzed optically. If necessary, the decolorizing step and the optical analysis steps are repeated until a selected level of decolorization is obtained. | 2014-02-27 |
20140057339 | SYSTEMS AND METHODS FOR GENETIC AND BIOLOGICAL ANALYSIS - The invention relate to systems and methods for sequencing polynucleotides, as well as detecting reactions and binding events involving other biological molecules. The systems and methods may employ chamber-free devices and nanosensors to detect or characterize such reactions in high-throughput. Because the system in many embodiments is reusable, the system can be subject to more sophisticated and improved engineering, as compared to single use devices. | 2014-02-27 |
20140057340 | DEVICES FOR DETECTING OR FILTERING TUMOR CELLS - Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells. | 2014-02-27 |
20140057341 | LIVE BIOLOAD DETECTION USING MICROPARTICLES - The present invention provides methods to concentrate cells onto microparticles, to concentrate the microparticles, and to detect the cells. The present invention also includes unitary sample preparation and detection devices to be used in accordance with the methods. | 2014-02-27 |
20140057342 | CULTURE APPARATUS, CULTURE APPARATUS SYSTEM, CULTURE OPERATION MANAGEMENT METHOD, AND NON-TRANSITORY STORAGE MEDIUM STORING PROGRAM - A culture apparatus includes a culture unit which cultures cells under a predetermined culture environment, and an imaging unit which captures an inspection image showing a state of a culture container which holds the cells or a state of the cells, further includes a carrying unit and a determining unit. The carrying unit delivers the culture container between at least one peripheral device to be used in a culture operation of the cells and the culture apparatus. The determining unit detects completion of the culture operation of the peripheral device, controls the imaging unit to capture the inspection image, and analyzes the inspection image to determine whether or not the culture operation by the peripheral device is appropriate. | 2014-02-27 |
20140057343 | ENERGY PRODUCTION SYSTEMS UTILIZING RUMINANT ANIMAL METHANE EMISSIONS - A process for the utilization of the methane produced by enteric fermentation, specifically to a process that utilizes methane produced by ruminant animals through enteric fermentation as a source of carbon and/or energy for the directed production of methane-based goods or processes is provided. | 2014-02-27 |
20140057344 | SEPARATION APPARATUS AND USE THEREOF - Separating apparatus, comprising a sedimentation settler and a collection vessel disposed underneath and being in fluid communication with the sedimentation settler, the collection vessel forming a receiving chamber having an outlet at or adjacent to the chamber bottom and having an inlet opening, wherein the collection vessel is arranged such the flow direction of the fluid in the area underneath the sedimentation settler is substantially in line with the direction of the channels of the sedimentation settler. | 2014-02-27 |
20140057345 | Polypropylene Resin Formulation for Autoclave Applications - A method including supplying a polypropylene resin, blending the polypropylene resin with Zinc Stearate, and forming a molded article from the polypropylene resin. Further, an article including a polypropylene resin blended with Zinc Stearate. | 2014-02-27 |
20140057346 | CULTURE PLATE WITH FIBER-COATED BOTTOM SURFACE - A cell culture plate that includes an upper portion having at least one discrete chamber with a top edge and a bottom edge; a substantially flat lower portion, wherein at least one layer of polymer fibers has been deposited on the upper surface of the lower portion, and wherein the at least one layer of polymer fibers is conducive to the growth of biological cells thereon; and wherein the bottom edge of the at least one discrete chamber is hermetically sealed to the fiber-coated upper surface of the lower portion to form a well using adhesives, laser welding, or ultrasonic welding. | 2014-02-27 |
20140057347 | METHOD AND APPARATUS FOR PREPARING CYTOLOGICAL SPECIMENS - An automated system for preparing a plurality of cytological specimens from a plurality of fluid samples in vials includes an apparatus for collecting a monolayer of cells from each sample and transferring the cells to a microscope slide for fixing, staining, and inspection. The system includes a first loading station for receiving the sample vials, a second loading station for receiving consumables such as filter membranes, a slide dispenser, and an unloading area for removing completed specimen slides. To maintain one-to-one correlation between the samples and specimens produced therefrom, the system includes a subsystem for identifying each sample and permanently marking each slide with corresponding indicia prior to transferring the specimen thereto. | 2014-02-27 |
20140057348 | Novel Culture System for Ex Vivo Development - The present invention provides methods for the culture of animal pluripotent stem cells and their differentiated progeny cells, tissues, and organs, and nonhuman animal embryos and fetuses. | 2014-02-27 |
20140057349 | Steroidal Ligands and Their Use in Gene Switch Modulation - The present invention relates to steroidal ligands for use in nuclear receptor-based inducible gene expression systems. The invention further relates to methods of modulating the expression of genes of interest with a system containing one or more nuclear receptor complexes and one or more steroidal ligands. Further aspects include ligand compositions including therapeutic compositions. | 2014-02-27 |
20140057350 | Compositions Comprising Human Embryonic Stem Cells and Their Derivatives, Methods of Use, and Methods of Preparation - The present invention relates to a pharmaceutical composition comprising of preparations of human embryonic stem (hES) cells and their derivatives and methods for their transplantation into the human body, wherein transplantation results in the clinical reversal of symptoms, cure, stabilization or arrest of degeneration of a wide variety of presently incurable and terminal medical conditions, diseases and disorders. The invention further relates to novel processes of preparing novel stem cell lines which are free of animal products, feeder cells, growth factors, leukaemia inhibitory factor, supplementary mineral combinations, amino acid supplements, vitamin supplements, fibroblast growth factor, membrane associated steel factor, soluble steel factor and conditioned media. This invention further relates to the isolation, culture, maintenance, expansion, differentiation, storage, and preservation of such stem cells. | 2014-02-27 |
20140057351 | IDEOTYPICALLY MODULATED PHARMACOEFFECTORS FOR SELECTIVE CELL TREATMENT - In a method embodiment, a method includes introducing a plurality of Ideotypically Modulated Pharmacoeffectors (IMP) into a population of cells. Each IMP may include a detection domain and an activation domain. One or more epitopes is bound by the detection domain. The activation domain is activated in response to the binding. Applications may include but are not limited to viral infections, other intracellular infections, cancers, vector-borne diseases, autoimmune diseases, cellular diseases, cellular enhancement, and research. | 2014-02-27 |
20140057352 | METHODS FOR THE IDENTIFICATION OF AGENTS THAT INHIBIT MESENCHYMAL-LIKE TUMOR CELLS OR THEIR FORMATION - The present invention provides tumor cell preparations for use as models of the EMT process for use in the identification of anti-cancer agents, wherein said tumor cell preparations comprise cells of the epithelial tumor cell line H1650, which are stimulated by receptor ligands to induce EMT, or which have been engineered to inducibly express a protein that stimulates EMT. The present invention also provides methods of identifying potential anti-cancer agents by using such tumor cell preparations to identify agents that inhibit EMT, stimulate MET, or inhibit the growth of mesenchymal-like cells. Such agents should be particularly useful when used in conjunction with other anti-cancer drugs such as EGFR and IGF-1R kinase inhibitors, which appear to be less effective at inhibiting tumor cells that have undergone an EMT. | 2014-02-27 |
20140057353 | METHOD FOR PRODUCING HEMATOPOIETIC STEM CELLS USING PYRAZOLE COMPOUNDS - An expanding agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful as a therapy for various hematopoietic diseases and useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy is provided. | 2014-02-27 |
20140057354 | ANTIGEN-SPECIFIC REGULATORY T-CELL INDUCTION - The present invention relates to an infectious particle having a surface displaying a ligand binding to a CD4 receptor for selectively infecting dividing CD4 | 2014-02-27 |
20140057355 | SOMATIC CELL REPROGRAMMING - The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method. | 2014-02-27 |
20140057356 | ESTIMATING DIFFUSION COEFFICIENT FOR A RESERVOIR STIMULATION FLUID - The subject disclosure relates to matrix acidizing. More specifically, systems and methods are described for estimating a diffusion coefficient for an acid fluid used to stimulate a subterranean reservoir wherein a spent acid is formulated that includes one or more by-products of the reaction between the fluid and rock. A rock sample, such as in the form of a rotating disk is exposed to spent acid under elevated pressure and temperature conditions while the fluid is sampled and analyzed. A diffusion coefficient for the spend acid is estimated. | 2014-02-27 |
20140057357 | METHOD FOR QUANTITATIVELY DETECTING 8-OXO 2'-DEOXYGUANOSINE IN AQUEOUS SAMPLE SOLUTION WITH HIGH SENSITIVITY - There is provided a method for quantitatively detecting 8-oxo 2′-deoxyguanosine in an aqueous sample solution with high sensitivity. A method for quantitatively detecting 8-oxo 2′-deoxyguanosine in an aqueous sample solution, including the steps of 1) immobilizing a fluorescent probe molecule showing a fluorescence response specific to 8-oxo 2′-deoxyguanosine on surfaces of fine particles via a spacer unit and bringing the sample solution into contact with the fine particles, and 2) measuring a physical property of the fine particles before and after the contact with the sample solution to determine a change in the physical property. | 2014-02-27 |
20140057358 | ANALYSIS OF SULFATED POLYSACCHARIDES - The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described. | 2014-02-27 |
20140057359 | APPARATUS AND METHOD FOR ANALYZING SAMPLE FLUIDS - The invention relates to an apparatus and a method for analyzing sample fluids, in particular for analyzing blood samples, for example for the purpose of determining the glucose content, with the same apparatus. A cavity delimited by a carrier tape is hereby positioned above a sensor surface, sample fluid is received in the cavity, at least one value of the sample fluid is measured, the cavity containing the sample fluid is removed from the sensor surface, and a regeneration agent is supplied to the sensor surface by way of the carrier tape. | 2014-02-27 |
20140057360 | ARRANGEMENT AND METHOD FOR DETECTING HYDROGEN PEROXIDE - An arrangement for detecting hydrogen peroxide includes a sample space configured to receive a hydrogen-peroxide-containing gas. The sample space is fluidically connected to a hydrogen-peroxide-selective colorimetric detection reagent. The arrangement also includes at least one radiation source configured to irradiate the detection reagent and at least one detector configured to detect at least one optical property of the colorimetric detection reagent. This arrangement enables detection of hydrogen peroxide in the gaseous phase without the need to transfer hydrogen peroxide to the liquid phase. As a result, a simplified measurement behavior and additionally a highly sensitive measurement are attained. | 2014-02-27 |
20140057361 | HEADSPACE SAMPLING DEVICE AND METHOD FOR SAMPLING - A device and method for headspace sampling is disclosed herein. The headspace sampling device comprises a sample holding device configured to be sealed in a vial. The sample holding device has a pair of electrodes gap spaced from one another and a basket extending between the electrodes configured to hold a sample. The basket is configured to heat a sample held therewith and volatize at least a portion of the sample upon an electrical current being passed through the electrodes and the basket. | 2014-02-27 |
20140057362 | LATERAL FLOW ASSAY ANALYSIS - Lateral flow assay analysis is shown and described. In one embodiment, the lateral flow assay comprises a surface having a reflectance profile that is adapted to enable monitoring of the assay continuously until the detection of an analyte. In other embodiments, a lateral flow assay system includes an incubator and a reader, wherein the incubator incubates the assay concurrently as the reader generates a test result. Further, an assay measurement apparatus may include an optical detector to perform continuous image detection of the assay to generate a diagnostic test result. | 2014-02-27 |
20140057363 | Method of Reducing Liquid Volume Surrounding Beads - The invention provides droplet actuators and droplet actuator techniques. Among other things, the droplet actuators and methods are useful for manipulating beads on a droplet actuator, such as conducting droplet operations using bead-containing droplets on a droplet actuator. For example, beads may be manipulated on a droplet actuator in the context of executing a sample preparation protocol and/or an assay protocol. An output of the methods of the invention may be beads prepared for execution of an assay protocol. Another output of the methods of the invention may be results of an assay protocol executed using beads. Among the methods described herein are methods of concentrating beads in droplets, methods of washing beads, methods of suspending beads, methods of separating beads, methods of localizing beads within a droplet, methods of forming emulsions in which droplets include beads, methods of loading beads into a droplet operations gap of a droplet actuator, methods of organizing beads in a monolayer, and methods of capturing, trapping or restraining beads. | 2014-02-27 |
20140057364 | METHOD OF DIAGNOSING ALZHEIMERS DISEASE USING SALIVA - Provided is a method of diagnosing Alzheimer's disease. The method of diagnosing Alzheimer's disease includes preparing magnetic particles having primary capture antibodies specifically bonded with beta-amyloid adsorbed thereon, introducing saliva containing beta-amyloid into the magnetic particles to bond the beta-amyloid contained in the saliva with the primary capture antibodies, bonding secondary capture antibodies labeled with fluorescent substances to the magnetic particles bonded with the beta-amyloid to form a complex, disposing the complex in a channel region of an photoelectric conversion device in which photoelectric current is changed according to an amount of incident light, and measuring photoelectric current changed by light excited from the complex to quantify a concentration of the beta-amyloid contained in the saliva. | 2014-02-27 |
20140057365 | TEST DEVICE AND METHOD FOR COLORED PARTICLE IMMUNOASSAY - A test device and method for colored particle immunoassay. A colorimetric monoclonal antibody is disposed on a receiving piece having a simple structure or in an entrance of a through-hole of a transparent tubular body, such that the monoclonal antibody bonded to micro gold very rapidly reacts with an antigen of a liquid sample. The liquid sample can arrive at a C site and a T site without either a filter or a permeable material having capillary tubes. The C site and the T site are disposed on the interior of the through-hole. This simplifies the structure, thereby reducing the cost of manufacture. The liquid sample can rapidly arrive at the C site and the T site through the through-hole of the transparent tubular body without, so that antibodies of the C site and the T site can react with the antigen in a very short time. | 2014-02-27 |
20140057366 | SENSOR DEVICE FOR MAGNETICALLY ACTUATED PARTICLES - The invention relates to a sensor device ( | 2014-02-27 |
20140057367 | ASSAYS FOR THE DETECTION OF ANTI-TNF DRUGS AND AUTOANTIBODIES - The present invention provides assays for detecting and measuring the presence or level of anti-TNFα drug therapeutics and autoantibodies in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNFα drug therapeutics to detect the presence or level of autoantibodies (e.g., HACA and/or HAHA) against the drug. | 2014-02-27 |
20140057368 | METHODS FOR DETERMINING LIGAND BINDING TO A TARGET PROTEIN USING A THERMAL SHIFT ASSAY - The invention is directed to a method of determining whether a non-purified sample contains a target protein bound to a ligand of interest comprising the steps of: a) exposing said non-purified sample to a temperature which is capable of causing or enhancing precipitation of the unbound target protein to a greater extent than it is capable of causing or enhancing precipitation of the target protein bound to said ligand; b) processing the product of step a) in order to separate soluble from insoluble protein; and c) analysing either or both the soluble and insoluble protein fractions of step b) for the presence of target protein, wherein said target protein is not detected on the basis of enzymatic activity of a tag, peptide, polypeptide or protein fused thereto. Particularly, the invention may be used to determine whether drugs can bind to their protein targets in samples derived from patients to ascertain whether a certain drug can be used in a therapy for that patient. Additionally, the invention is directed to an instrument for use in the methods of the invention and use of a kit in the methods of the invention comprising an antibody and/or a non-protein fusion tag. | 2014-02-27 |
20140057369 | METHODS FOR FORMING INTERCONNECTION LINE USING SCREEN PRINTING TECHNIQUE - Methods of forming an interconnection line pattern using a screen printing technique. The method includes preparing a substrate having unevenness, aligning a stencil mask on the substrate, and printing a paste including materials for forming the interconnection line pattern on a convex portion of the unevenness formed on the substrate. | 2014-02-27 |
20140057370 | DUAL WAFER SPIN COATING - A method of bonding a first substrate and a second substrate includes the steps of rotating first substrate with an adhesive mass thereon, and second substrate contacting the mass and overlying the first substrate, controlling a vertical height of a heated control platen spaced apart from and not contacting the second substrate so as to control a temperature of the adhesive mass, so as to at least one of bond the first and second substrates in alignment with one another, or achieve a sufficiently planar adhesive interface between the first and second substrates. | 2014-02-27 |
20140057371 | HIGH PRODUCTIVITY COMBINATORIAL WORKFLOW FOR POST GATE ETCH CLEAN DEVELOPMENT - Combinatorial workflow is provided for evaluating cleaning processes after forming a gate structure of transistor devices, to provide optimized process conditions for gate stack formation, including metal gate stack using high-k dielectrics. NMOS and PMOS transistor devices are combinatorially fabricated on multiple regions of a substrate, with each region exposed to a different cleaning chemical and process. The transistor devices are then characterized, and the data are compared to categorize the potential damages of different cleaning chemicals and processes. Optimized chemicals and processes can be obtained to satisfy desired device requirements. | 2014-02-27 |
20140057372 | METHOD FOR ON-WAFER HIGH VOLTAGE TESTING OF SEMICONDUCTOR DEVICES - A method for wafer high voltage testing of semiconductor devices is disclosed. The method involves adding a patterning layer onto a passivation layer of the semiconductor devices and then etching vias through the passivation layer to expose conductive test points. Testing of the semiconductor devices begins with engaging the conductive test points with high voltage test probes of a testing apparatus and then applying a high voltage test sequence to the conductive test points via the high voltage test probes. The testing of the semiconductor devices concludes by disengaging the high voltage test probes from a last one of the semiconductor devices and then removing the patterning layer from the passivation layer of the semiconductor devices. | 2014-02-27 |
20140057373 | Modular Printhead for OLED Printing - The disclosure generally relates to a modular printhead configured for ease of access and quick replacement of the printhead. In one embodiment, the disclosure is directed to an integrated printhead which includes: a printhead die supporting a plurality of micropores thereon; a support structure for supporting the printhead die; a heater interposed between the printhead die and the support structure; and an electrical trace connecting the heater to a supply source. The support structure accommodates the electrical trace through a via formed within it so as to form a solid state printhead containing all of the connections within and providing easily replaceable printhead. | 2014-02-27 |
20140057374 | OPTICAL-SEMICONDUCTOR DEVICE - The present invention relates to an optical-semiconductor device, which is prepared by: arranging a sheet for optical-semiconductor element encapsulation including an encapsulating resin layer capable of embedding an optical-semiconductor element and a wavelength conversion layer containing light wavelength-converting particles and being laminated directly or indirectly on the encapsulating resin layer, on an optical-semiconductor element-mounting substrate so that the encapsulating resin layer faces the optical-semiconductor element-mounting substrate; followed by compression-molding, in which the wavelength conversion layer is present on an upper part of a molded body in which the optical-semiconductor element is embedded therein, but is not present on a side surface of the molded body. | 2014-02-27 |
20140057375 | WAVELENGTH CONVERTING MATERIAL DEPOSITION METHODS AND ASSOCIATED ARTICLES - Systems and methods related to the arrangement of regions containing wavelength-converting materials, and associated articles, are provided. | 2014-02-27 |
20140057376 | Deposition Donor Substrate and Method for Manufacturing Light-Emitting Device - One surface of a first substrate provided with at least light-absorbing layers separately formed, partition layers each formed between the light-absorbing layers and having an inverse taper shape, and material layers formed on the light-absorbing layers and on the partition layers so that the material layers are separated from each other is disposed to face a deposition target surface of a second substrate; light irradiation is performed from the other surface of the first substrate, only the material layers in regions overlapped with the light-absorbing layers are heated and evaporated to the deposition target surface of the second substrate. | 2014-02-27 |
20140057377 | METHOD FOR MANUFACTURING DEVICE - A method for manufacturing a device having a concavo-convex structure includes forming an organic resist film on an n-type semiconductor layer in which a fine concavo-convex structure is to be formed; forming a silicon-containing resist film on the organic resist film; patterning the silicon-containing resist film by nanoimprint; oxidizing the silicon-containing resist film with oxygen-containing plasma to form a silicon oxide film; dry-etching the organic resist film by using the silicon oxide film as an etching mask; dry-etching the n-type semiconductor layer by using the silicon oxide film and the organic resist film as an etching masks; and removing the silicon oxide film and the organic resist film. | 2014-02-27 |
20140057378 | ORGANIC LIGHT EMITTING DISPLAY APPARATUS AND METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING DISPLAY APPARATUS - An organic light emitting display (OLED) apparatus and a method of manufacturing the same, the OLED apparatus including: a substrate; an active layer formed on the substrate; a gate electrode insulated from the active layer; source and drain electrodes insulated from the gate electrode and electrically connected to the active layer; a pixel defining layer formed on the source and drain electrodes, having an aperture to expose one of the source and drain electrodes; an intermediate layer formed in the aperture and comprising an organic light emitting layer; and a facing electrode which is formed on the intermediate layer. One of the source and drain electrodes has an extension that operates as a pixel electrode. The aperture exposes the extended portion. The intermediate layer is formed on the extended portion. | 2014-02-27 |
20140057379 | Photoresist Film and Manufacturing Method for Organic Light Emitting Display Device Using the Same - Disclosed is a photoresist film including a light-to-heat conversion layer on a support film, and a thermo-responsive polymer layer on the light-to-heat conversion layer, wherein the photoresist film is easily detached from a transfer substrate through a temperature adjustment and detach film since the photoresist film includes thermo-responsive polymer. | 2014-02-27 |
20140057380 | NITRIDE-TYPE SEMICONDUCTOR ELEMENT AND PROCESS FOR PRODUCTION THEREOF - A nitride-based semiconductor device includes a p-type Al | 2014-02-27 |
20140057381 | VERTICAL LIGHT-EMITTING DEVICES HAVING PATTERNED EMITTING UNIT AND METHODS OF MANUFACTURING THE SAME - Example embodiments are directed to a light-emitting device including a patterned emitting unit and a method of manufacturing the light-emitting device. The light-emitting device includes a first electrode on a top of a semiconductor layer, and a second electrode on a bottom of the semiconductor layer, wherein the semiconductor layer is a pattern array formed of a plurality of stacks. A space between the plurality of stacks is filled with an insulating layer, and the first electrode is on the insulating layer. | 2014-02-27 |
20140057382 | METHODS FOR FABRICATING MEMS STRUCTURES BY ETCHING SACRIFICIAL FEATURES EMBEDDED IN GLASS - In an embodiment a method of fabricating a MEMS structure is provided. The method includes fabricating a working structure in a doped layer proximate a first surface of a silicon substrate. The first surface of the silicon substrate is bonded to a first planar glass structure having a first one or more sacrificial features embedded therein. The method also includes etching to remove a bulk of the silicon substrate, wherein the bulk is reverse of the first surface on the silicon substrate, wherein etching removes the bulk and leaves the working structure bonded to the first planar glass structure. The method also includes etching to remove the first one or more sacrificial features from the first planar glass structure. | 2014-02-27 |
20140057383 | METHOD OF PRODUCING WAFER FOR SOLAR CELL, METHOD OF PRODUCING SOLAR CELL, AND METHOD OF PRODUCING SOLAR CELL MODULE - Provided is a method of producing a wafer for a solar cell that can produce the solar cell with high conversion efficiency. | 2014-02-27 |
20140057384 | SOLAR CELL AND FABRICATING METHOD THEREOF - Discussed herein are a solar cell and a fabricating method thereof. The solar cell includes a first conductivity-type semiconductor substrate, a second conductivity-type semiconductor layer formed on a front surface of the first conductivity-type semiconductor substrate, and having a conductivity opposite to that of the first conductivity-type semiconductor substrate, an anti-reflection film including at least one opening exposing a part of a surface of the second conductivity-type semiconductor layer, and formed on the second conductivity-type semiconductor layer, at least one front electrode contacting a part of the surface of the second conductivity-type semiconductor layer exposed through the at least one opening, and at least one rear electrode formed on a rear surface of the first conductivity-type semiconductor substrate, wherein the at least one front electrode includes a metal containing silver and lead-free glass frit. | 2014-02-27 |
20140057385 | III-V PHOTOVOLTAIC ELEMENT AND FABRICATION METHOD - A solar cell structure includes stacked layers in reverse order on a germanium substrate. A heterostructure including an (In)GaAs absorbing layer and a disordered emitter layer is provided in the solar cell structures. Controlled spalling may be employed as part of the fabrication process for the solar cell structure, which may be single or multi-junction. | 2014-02-27 |
20140057386 | Systems and Methods for Depositing and Charging Solar Cell Layers - Systems and methods of the present invention may be used to charge a layer (such as a passivation layer and/or antireflective layer) of a solar cell (e.g., wafer) with a positive or negative charge. The layer may retain the charge to improve operation of the solar cell. The charged layer may include any suitable dielectric material capable of retaining either a negative or a positive charge. Systems and methods of the present invention permit in-situ charging of a layer. Charging of a layer may be accomplished during or after deposition of the layer including after completing the whole solar cell process, in other words, on a finished cell. | 2014-02-27 |
20140057387 | Systems and Methods for Depositing and Charging Solar Cell Layers - Systems and methods of the present invention may be used to charge a layer (such as a passivation layer and/or antireflective layer) of a solar cell (e.g., wafer) with a positive or negative charge. The layer may retain the charge to improve operation of the solar cell. The charged layer may include any suitable dielectric material capable of retaining either a negative or a positive charge. Systems and methods of the present invention permit in-situ charging of a layer. Charging of a layer may be accomplished during or after deposition of the layer including after completing the whole solar cell process, in other words, on a finished cell. | 2014-02-27 |
20140057388 | Systems and Methods for Depositing and Charging Solar Cell Layers - Systems and methods of the present invention may be used to charge a layer (such as a passivation layer and/or antireflective layer) of a solar cell (e.g., wafer) with a positive or negative charge. The layer may retain the charge to improve operation of the solar cell. The charged layer may include any suitable dielectric material capable of retaining either a negative or a positive charge. Systems and methods of the present invention permit in-situ charging of a layer. Charging of a layer may be accomplished during or after deposition of the layer including after completing the whole solar cell process, in other words, on a finished cell. | 2014-02-27 |
20140057389 | PHOTOVOLTAIC BACK CONTACT - A method to preparing Cadmium telluride surface before forming metal back contact is disclosed. The method can include removing carbon from Cadmium telluride surface. | 2014-02-27 |
20140057390 | MULTI-NOZZLE ORGANIC VAPOR JET PRINTING - Systems and methods are provided in which individual elements of a thin patterned film are deposited by two or more nozzles having different geometries. The different nozzle geometries may include one or more of different throttle diameters, different exhaust diameters, different cross-sectional shapes, different bore angles, different wall angles, different exhaust distances from the substrate, and different leading edges relative to the direction of movement of the nozzles or the substrate. Methods may include steps of ejecting a carrier gas and a material from a plurality of nozzles and depositing the material on the substrate in a plurality of laterally spaced elements, each of the elements deposited by a separate nozzle group. At least one of the nozzles in a group of nozzles depositing an element may be configured to deposit the material on the substrate in a width that is smaller than the width of the element. | 2014-02-27 |
20140057391 | Carrier Warpage Control for Three Dimensional Integrated Circuit (3DIC) Stacking - An embodiment method of forming a package-on-package (PoP) device includes temporarily mounting a substrate on a carrier, stacking a first die on the substrate, at least one of the die and the substrate having a coefficient of thermal expansion mismatch relative to the carrier, and stacking a second die on the first die. The substrate may be formed from one of an organic substrate, a ceramic substrate, a silicon substrate, a glass substrate, and a laminate substrate. | 2014-02-27 |
20140057392 | Copper Post Solder Bumps on Substrates - A method comprises forming semiconductor flip chip interconnects having electrical connecting pads and electrically conductive posts terminating in distal ends operatively associated with the pads. We solder bump the distal ends by injection molding, mask the posts on the pads with a mask having a plurality of through hole reservoirs and align the reservoirs in the mask to be substantially concentric with the distal ends. Injecting liquid solder into the reservoirs and allowing it to cool provides solidified solder on the distal ends, which after mask removal produces a solder bumped substrate which we position on a wafer to leave a gap between the wafer and the substrate. The wafer has electrically conductive sites on the surface for soldering to the posts. Abutting the sites and the solder bumped posts followed by heating joins the wafer and substrate. The gap is optionally filled with a material comprising an underfill. | 2014-02-27 |
20140057393 | Semiconductor Device Package and Methods of Packaging Thereof - In one embodiment of the present invention, a method of forming a semiconductor device includes forming a device region in a first region of a semiconductor substrate, and forming an opening in a second region of the semiconductor substrate. The method further includes placing a semiconductor die within the opening, and forming a first metallization level over the semiconductor die and the device region. | 2014-02-27 |
20140057394 | METHOD FOR MAKING A DOUBLE-SIDED FANOUT SEMICONDUCTOR PACKAGE WITH EMBEDDED SURFACE MOUNT DEVICES, AND PRODUCT MADE - A manufacturing process includes forming a reconstituted wafer, including embedding semiconductor dice in a molding compound layer and forming through-wafer vias in the layer. A fan-out redistribution layer is formed on a front side of the wafer, with electrical traces interconnecting the dice, through-wafer vias, and contact pads positioned on the redistribution layer. Solder balls are positioned on the contact pads and a molding compound layer is formed on the redistribution layer, reinforcing the solder balls. A second fan-out redistribution layer is formed on a back side of the wafer, with electrical traces interconnecting back ends of the through-wafer vias and contact pads positioned on a back face of the second redistribution layer. Flip-chips and/or surface-mounted devices are coupled to the contact pads of the second redistribution layer and encapsulated in an underfill layer formed on the back face of the second redistribution layer. | 2014-02-27 |
20140057395 | SEMICONDUCTOR HOUSING AND METHOD FOR THE PRODUCTION OF A SEMICONDUCTOR HOUSING - A semiconductor housing is provided that includes a metal support and a semiconductor body, a bottom side thereof being connected to the metal support. The semiconductor body has metal surfaces that are connected to pins by bond wires and a plastic compound, which completely surrounds the bond wires and partially surrounds the semiconductor body. The plastic compound has an opening on the top side of the semiconductor body, and a barrier is formed on the top side of the semiconductor body. The barrier has a top area and a base area spaced from the edges of the semiconductor body and an internal clearance of the barrier determines a size of the opening. Whereby, a portion of the plastic compound has a height greater than the barrier, and a fixing layer is formed between the base area of the barrier and the top side of the semiconductor body. | 2014-02-27 |
20140057396 | Method of Manufacturing a Component Comprising Cutting a Carrier - A method of manufacturing a component is disclosed. An embodiment of the method comprises dicing a carrier in a plurality of components, the carrier being disposed on a support carrier, after dicing, placing a connection layer on the carrier and removing the components from the support carrier. | 2014-02-27 |
20140057397 | DIODE-TRIGGERED SILICON CONTROLLED RECTIFIER WITH AN INTEGRATED DIODE - Device structures, design structures, and fabrication methods for a silicon controlled rectifier. A well of a first conductivity type is formed in a device region, which may be defined from a device layer of a semiconductor-on-insulator substrate. A doped region of a second conductivity type is formed in the well. A cathode of a silicon controlled rectifier and a cathode of a diode are formed in the device region. The silicon controlled rectifier comprises a first portion of the well and an anode comprised of a first portion of the doped region. The diode comprises a second portion of the well and an anode comprised of a second portion of the doped region. | 2014-02-27 |
20140057398 | Memory Cells, Memory Arrays, Methods Of Forming Memory Cells, And Methods Of Forming A Shared Doped Semiconductor Region Of A Vertically Oriented Thyristor And A Vertically Oriented Access Transistor - A memory cell includes a thyristor having a plurality of alternately doped, vertically superposed semiconductor regions; a vertically oriented access transistor having an access gate; and a control gate operatively laterally adjacent one of the alternately doped, vertically superposed semiconductor regions. The control gate is spaced laterally of the access gate. Other embodiments are disclosed, including methods of forming memory cells and methods of forming a shared doped semiconductor region of a vertically oriented thyristor and a vertically oriented access transistor. | 2014-02-27 |
20140057399 | Using Fast Anneal to Form Uniform Ni(Pt)Si(Ge) Contacts on SiGe Layer - Techniques for forming a smooth silicide without the use of a cap layer are provided. In one aspect, a cap layer-free method for forming a silicide is provided. The method includes the following steps. A semiconductor material selected from: silicon and silicon germanium is provided. At least one silicide metal is deposited on the semiconductor material. The semiconductor material and the at least one silicide metal are annealed at a temperature of from about 400° C. to about 800° C. for a duration of less than or equal to about 10 milliseconds to form the silicide. A FET device and a method for fabricating a FET device are also provided. | 2014-02-27 |
20140057400 | Thin Film Transistor Manufacturing Method - The present invention provides a thin film transistor (TFT) manufacturing method and a TFT, a source electrode or drain electrode of the TFT is electrically connected to a data line directly during a forming process by providing a through hole in a surface above the data line of the TFT, so as to save the process cost. Further, the source electrode and drain electrode of the TFT are also manufactured with poly-silicon rather than metal material used in prior art, processing steps are simplified, thereby further saving the process cost. | 2014-02-27 |
20140057401 | COMPOUND SEMICONDUCTOR DEVICE WITH MESA STRUCTURE - A compound semiconductor device having mesa-shaped element region, and excellent characteristics are provided. The compound semiconductor device has: an InP substrate; an epitaxial lamination mesa formed above the InP substrate and including a channel layer, a carrier supply layer above the channel layer and a contact cap layer above the carrier supply layer; ohmic source electrode and drain electrode formed on the cap layer; a recess formed by removing the cap layer between the source and drain electrodes, and exposing the carrier supply layer; an insulating film formed on the cap layer and retracted from an edge of the cap layer away from the recess; a gate electrode extending from the carrier supply layer in the recess to outside of the mesa; and air gap formed by removing side portion of the channel layer facing the gate electrode outside the mesa. | 2014-02-27 |
20140057402 | Methods of Forming Memory Arrays and Semiconductor Constructions - Some embodiments include methods of forming semiconductor constructions. A heavily-doped region is formed within a first semiconductor material, and a second semiconductor material is epitaxially grown over the first semiconductor material. The second semiconductor material is patterned to form circuit components, and the heavily-doped region is patterned to form spaced-apart buried lines electrically coupling pluralities of the circuit components to one another. At least some of the patterning of the heavily-doped region occurs simultaneously with at least some of the patterning of the second semiconductor material. | 2014-02-27 |
20140057403 | METHOD FOR FABRICATING SEMICONDUCTOR DEVICE - A method for fabricating a semiconductor device is provided. A fin of a first conductivity type is formed on a substrate of the first conductivity type. A gate is formed on the substrate, wherein the gate covers a portion of the fin. Source and drain regions of a second conductivity type are formed in the fin at respective sides of the gate. A punch-through stopper (PTS) of the first conductivity type is formed in the fin underlying the gate and between the source and drain regions, wherein the PTS has an impurity concentration higher than that of the substrate. A first impurity of the second conductivity type is implanted into the PTS, so as to compensate the impurity concentration of the PTS. | 2014-02-27 |
20140057404 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE - A method of manufacturing a semiconductor device is disclosed. In one embodiment, the method comprises: forming a gate stack on a substrate; etching the substrate on both sides of the gate stack to form C-shaped source/drain grooves; and wet-etching the C-shaped source/drain grooves to form Σ-shaped source/drain grooves. With this method, it is possible to effectively increase stress applied to a channel region, to accurately control a depth of the source/drain grooves, and to reduce roughness of side walls and bottom portions of the grooves and thus reduce defects by etching the C-shaped source/drain grooves and then further wet-etching them to form the Σ-shaped source/drain grooves. | 2014-02-27 |
20140057405 | METHOD OF FABRICATING P-TYPE SURFACE-CHANNEL LDMOS DEVICE WITH IMPROVED IN-PLANE UNIFORMITY - A method of fabricating a P-type surface-channel laterally diffused metal oxide semiconductor device includes forming a gate structure with polysilicon and metal silicide, and the processes of channel implantation, long-time high-temperature drive-in, formation of a heavily doped N-type polysilicon sinker and boron doping of a polysilicon gate, are performed in this order, thereby ensuring the gate not to be doped with boron during its formation. The high-temperature drive-in process is allowed to be carried out to form a channel with a desired width, and a short channel effect which may cause penetration or electric leakage of the resulting device is prevented. As the polysilicon gate is not processed by any high-temperature drive-in process after it is doped with boron, the penetration of boron through a gate oxide layer and the diffusion of N-type impurity contained in the heavily doped polysilicon sinker into the channel or other regions are prevented. | 2014-02-27 |
20140057406 | Integrated Circuitry Comprising Nonvolatile Memory Cells And Methods Of Forming A Nonvolatile Memory Cell - An integrated circuit has a nonvolatile memory cell that includes a first electrode, a second electrode, and an ion conductive material there-between. At least one of the first and second electrodes has an electrochemically active surface received directly against the ion conductive material. The second electrode is elevationally outward of the first electrode. The first electrode extends laterally in a first direction and the ion conductive material extends in a second direction different from and intersecting the first direction. The first electrode is received directly against the ion conductive material only where the first and second directions intersect. Other embodiments, including method embodiments, are disclosed. | 2014-02-27 |
20140057407 | High Voltage Resistor - Provided is a semiconductor device. The semiconductor device includes a resistor and a voltage protection device. The resistor has a spiral shape. The resistor has a first portion and a second portion. The voltage protection device includes a first doped region that is electrically coupled to the first portion of the resistor. The voltage protection device includes a second doped region that is electrically coupled to the second portion of the resistor. The first and second doped regions have opposite doping polarities. | 2014-02-27 |
20140057408 | RECTANGULAR CAPACITORS FOR DYNAMIC RANDOM ACCESS MEMORY (DRAM) AND DUAL-PASS LITHOGRAPHY METHODS TO FORM THE SAME - A rectangular capacitor for dynamic random access memory (DRAM) and a dual-pass lithography method to form the same are described. For example, a capacitor includes a trench disposed in a first dielectric layer disposed above a substrate. A cup-shaped metal plate is disposed along the bottom and sidewalls of the trench. A second dielectric layer is disposed on and conformal with the cup-shaped metal plate. A trench-fill metal plate is disposed on the second dielectric layer. The second dielectric layer isolates the trench-fill metal plate from the cup-shaped metal plate. The capacitor has a rectangular or near-rectangular shape from a top-down perspective. | 2014-02-27 |
20140057409 | Isolation Structure Profile for Gap Filing - An trench isolation structure and method for manufacturing the trench isolation structure are disclosed. An exemplary trench isolation structure includes a first portion and a second portion. The first portion extends from a surface of a semiconductor substrate to a first depth in the semiconductor substrate, and has a width that tapers from a first width at the surface of the semiconductor substrate to a second width at the first depth, the first width being greater than the second width. The second portion extends from the first depth to a second depth in the semiconductor substrate, and has substantially the second width from the first depth to the second depth. | 2014-02-27 |