09th week of 2016 patent applcation highlights part 25 |
Patent application number | Title | Published |
20160060324 | Methods and Compositions for Treating Bleeding Disorders - The present invention provides immune conjugates for inducing antigen specific immune tolerance to coagulation Factor VIII. The immune conjugates contain a FVIII protein or antigenic fragment that is conjugated to a binding moiety for a sialic acid binding Ig-like lectin (Siglec) expressed on B cells. The invention also provides methods of using the FVIII immune conjugates to induce immune tolerance to FVIII in a subject. Additionally provided in the invention are methods for treating bleeding disorders such as hemophilia A via the use of the FVIII immune conjugates and an unconjugated FVIII with coagulating activity. | 2016-03-03 |
20160060325 | Monoclonal Antibodies Capable of Reacting with a Plurality of Influenza Virus a Subtypes - Monoclonal antibodies directed against the influenza A virus are described, which have the advantageous and unpredicted property of being able to bind a plurality of subtypes of the influenza A virus. One preferred embodiment is the antibody designated as Fab28, which displays a neutralizing activity against a plurality of subtypes of the influenza A virus. Anti-idiotype antibodies directed against the monoclonal antibodies of the invention, immunogenic or vaccine compositions comprising the monoclonal antibodies of the invention are also described, as well as therapeutic, prophylactic and diagnostic applications for the monoclonal antibodies of the invention. The monoclonal antibodies of the invention can also be used for testing antibody preparations to be used as vaccines. | 2016-03-03 |
20160060326 | Antibody Therapeutics That Bind OprF and Oprl - There is disclosed compositions and methods relating to or derived from anti-OprF and anti-OprI antibodies. More specifically, there is disclosed fully human antibodies that bind OprF and OprI, OprF and OprI-antibody binding fragments and derivatives of such antibodies, and OprF and OprI-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having | 2016-03-03 |
20160060327 | Anti-Infective Binding Proteins that Bind AIP2 - There is disclosed compositions and methods relating to or derived from anti-AIP2 antibodies. More specifically, there is disclosed fully human antibodies that bind AIP2, AIP2-binding fragments and derivatives of such antibodies, and AIP2-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having AIP2 related disorders or conditions. There is also disclosed a method to treat | 2016-03-03 |
20160060328 | COMPOSITIONS AND METHODS FOR BINDING CYSTEINYL LEUKOTRIENES (CYSLTS) FOR TREATMENT OF DISEASE - Methods are provided for using antibodies and antibody fragments that bind one or more cysteinyl leukotrienes (cysLTs) for treatment of diseases, including inflammatory, respiratory and gastrointestinal diseases and conditions associated with aberrant levels of one or more cysLTs. Anti-cysLT antibodies and antigen-binding antibody fragments, and compositions containing such antibodies and antibody fragments, are also provided. | 2016-03-03 |
20160060329 | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF LUNG CANCER - The present invention relates to methods and compositions for the detection of lung cancer. More particularly, the present invention provides monoclonal antibodies for the detection of lung cancer. | 2016-03-03 |
20160060330 | POLYPEPTIDE VARIANTS WITH ALTERED EFFECTOR FUNCTION - The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof. | 2016-03-03 |
20160060331 | PREVENTION AND TREATMENT OF SYNUCLEINOPATHIC AND AMYLOIDOGENIC DISEASE - The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful prophylactic and therapeutic treatment of Parkinson's disease. | 2016-03-03 |
20160060332 | THERAPEUTIC DLL4 BINDING PROTEINS - Improved DLL4 binding proteins are described, including antibodies, CDR-grafted antibodies, human antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis, and/or other angiogenesis-dependent diseases such as ocular neovascularization, or angiogenesis-independent diseases characterized by aberrant DLL4 expression or activity such as autoimmune disorders including multiple sclerosis. | 2016-03-03 |
20160060333 | EARLY MARKER OF PROTEINURIA IN PATIENTS TREATED WITH AN ANTI-VEGF TREATMENT - This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided. | 2016-03-03 |
20160060334 | FGF MODULATION OF IN VIVO ANTIBODY PRODUCTION AND HUMORAL IMMUNITY - The invention provides methods for increasing or decreasing antibody production in vivo by inhibiting or promoting the activity of fibroblast growth factor-2 (FGF2) respectively. | 2016-03-03 |
20160060335 | MITIGATION AND REVERSAL OF FIBROSIS AND INFLAMMATION BY INHIBITION OF TL1A FUNCTION AND RELATED SIGNALING PATHWAYS - The invention relates to methods of treating fibrosis and inflammatory bowel disease. In one embodiment, the present invention treats gut inflammation by administering a therapeutically effective dosage of TL1A inhibitors and/or DR3 inhibitors to an individual. In another embodiment, the present invention provides a method of reversing tissue fibrosis in an individual by inhibiting TL1A-DR3 signaling function. | 2016-03-03 |
20160060336 | Methods for Treating Juvenile Idiopathic Arthritis - The invention provides methods and compositions for the treatment of juvenile idiopathic arthritis (JIA) where a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat JIA. In particular, the invention is directed to methods and compositions relating to a fixed dosing regimen for treating JIA with a TNFα inhibitor. | 2016-03-03 |
20160060337 | METHODS FOR TREATING PSORIASIS USING AN ANTI-IL-23 ANTIBODY - The invention relates to products and methods for treating psoriasis. The products relate to antibodies that inhibit native human IL-23 while sparing IL-12. One example describes a Phase 1, randomized, double-blind, placebo-controlled, ascending single dose study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of an anti-IL-23 antibody (AMG 139) in healthy subjects and subjects with moderate to severe psoriasis. | 2016-03-03 |
20160060338 | COMPOUND TARGETING IL-23A AND TNF-ALPHA AND USES THEREOF - The disclosure relates to compounds specific for IL23A and TNF-alpha, compositions comprising the compounds, and methods of use thereof. Nucleic acids, cells, and methods of production related to the compounds and compositions are also disclosed. | 2016-03-03 |
20160060339 | Folate Receptor 1 Antibodies and Immunoconjugates and Uses Thereof - Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to human folate receptor 1 are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided. | 2016-03-03 |
20160060340 | ANTI-FOLR1 ANTIBODY - The present invention provides an anti-human FOLR1 antibody against diseases associated with human FOLR1-expressing cells, which specifically recognizes and binds to an amino acid sequence of human FOLR1 or a conformational structure thereof and also has a high effector activity such as antibody-dependent cellular cytotoxicity activity (ADCC activity). The present invention can provide a monoclonal antibody which specifically recognizes and binds to the amino acid sequence of human FOLR1 or the conformational structure thereof and also has ADCC activity and CDC activity, or an antibody fragment thereof, a DNA encoding the antibody, a vector comprising the DNA, a transformant obtained by introducing the vector, a method for producing the antibody or the antibody fragment thereof using the transformant, and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment as an active ingredient. | 2016-03-03 |
20160060341 | T-CELL-SPECIFIC HUMANIZED SINGLE FRAGMENT ANTIBODY DELIVERY VEHICLE - The present invention relates to a humanized scFv delivery vehicle targeted to be human T-cell specific, and provides: a humanized scFv which comprises a heavy-chain variable region (VH) consisting of a polypeptide comprising an amino acid sequence given by sequence number 32 and comprises a light-chain variable region (VL) consisting of a polypeptide comprising an amino acid sequence given by sequence number 34; and a T-cell-specific drug or marker delivery vehicle comprising the humanized scFv. The humanized scFv of the present invention has minimalised antigenicity and has an effect which does not give rise to an immune reaction even when used in the human body, and thus can advantageously be used as a delivery vehicle for specifically delivering a target substance such as a siRNA gene or an immune reaction regulating protein to T-cells. | 2016-03-03 |
20160060342 | Markers of Acute Myeloid Leukemia Stem Cells - Markers of acute myeloid leukemia stem cells (AMLSC) are identified. The markers are differentially expressed in comparison with normal counterpart cells, and are useful as diagnostic and therapeutic targets. | 2016-03-03 |
20160060343 | CANCER TREATMENT - The present invention relates to methods of treating cancer, such as melanoma, by administering a CTLA4 antagonist to a subject with a serum C-Reactive Protein (CRP) concentration that is less than or equal to some amount. The invention further relates to methods of treating cancer by determining the level of serum CRP concentration in a subject, and then administering a CTLA4 antagonist if the CRP concentration is less than or equal to a certain amount. The invention further relates to, among other things, the use of serum CRP concentration as a predictive factor for a subject's response to a cancer treatment. | 2016-03-03 |
20160060344 | COMBINATION THERAPY FOR PD-L1 NEGATIVE TUMORS - The present invention features methods of treating lung cancer (e.g., NSCLC) with an anti-PD-L1 antibody and tremelimumab in a subject identified as having a PD-L1 negative tumor. | 2016-03-03 |
20160060345 | Novel EGFR-Binding Molecules and Immunoconjugates Thereof - Novel anti-cancer agents, including, but not limited to, antibodies and immunoconjugates, that bind to EGFR are provided. Methods of using the agents, antibodies, or immunoconjugates, such as methods of inhibiting tumor growth are further provided. | 2016-03-03 |
20160060346 | Modulation of Activity of Proneurotrophins - The present invention provides agents for inhibiting binding of a pro-neurotrophin to a Vps10p-domain receptor, in particular the binding of a pro-NGF or a pro-BDNF to a Sortilin receptor. The invention thus provides agents for the manufacture of a medicament, for treating and/or preventing disease or disorders such as but not limited to neurological, neuropsychiatric and ocular diseases, disorders, and degeneration as well as obesity, diabetes, pain and/or nociception in an individual. | 2016-03-03 |
20160060347 | ANTIBODIES TARGETING SPECIFICALLY HUMAN CXCR2 - This disclosure generally relates to antibodies or fragments thereof which interact with CXCR2. The disclosure further discloses antibodies, which bind to specific extracellular domains of CXCR2. The disclosure further relates to therapeutics comprising CXCR2-specific antibodies and methods of treatment using CXCR2-specific antibodies or fragments thereof. | 2016-03-03 |
20160060348 | ANTI-CD154 ANTIBODIES HAVING IMPAIRED FcR BINDING AND/OR COMPLEMENT BINDING PROPERTIES AND USE IN THERAPY - Improved anti-CD154 antibodies are provided herein which have ablated FcR binding and/or complement binding/activation. The use of these antibodies for inducing tolerance and treating immune diseases including autoimmunity, inflammation and allergic disorders is disclosed herein. | 2016-03-03 |
20160060349 | METHOD FOR INCREASING PYRO-GLUTAMIC ACID FORMATION OF A PROTEIN - A method for conversion of an N-terminal glutamine and/or glutamic acid residue of a protein to pyro-glutamic acid within a purification process. | 2016-03-03 |
20160060350 | CYTOTOXIC ANTIBODY DIRECTED AGAINST TYPE B LYMPHOID HEMATOPOIETIC PROLIFERATIONS - The present invention relates to a monoclonal antibody directed against the CD20 antigen, wherein the variable region of each of the light chains thereof is encoded by a sequence which shares at least 70% identity with murine nucleic acid sequence SEQ ID No. 5, the variable region of each of the heavy chains thereof is encoded by a sequence which shares at least 70% identity with murine nucleic acid sequence SEQ ID No. 7, and the constant regions of light and heavy chains thereof are constant regions from a non-murine species, as well as for activation of FcγRIIIA receptors in immune effector cells, and for the manufacture of a drug especially for the treatment of leukaemia or lymphoma. | 2016-03-03 |
20160060351 | Use of C5AR Antagonists - C5a and C5aR stimulate the inflammatory response and C5aR antagonist can counteract this function performing as an anti-inflammatory agents. This functionality is considered useful in treatment of inflammatory diseases including auto immune diseases. In addition it has been found that C5a and C5aR have a function in relation to bone homeostasis and remodelling and that C5aR antagonists are useful for treatment of bone damage, such as bone erosion and loss of bone density and for treatment of bone damage and cartilage damage. | 2016-03-03 |
20160060352 | COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF HEPATOCELLULAR CARCINOMA - Disclosed herein are compositions and methods to treat hepatocellular carcinoma. In one embodiment, a method of treating a subject with hepatocellular carcinoma comprises administering a therapeutically effective amount of an immunoconjugate (VB4-845) comprising an antibody conjugated to an effector molecule, and wherein the antibody recognizes epithelial cell adhesion molecule (Ep-CAM). The effector molecule may be | 2016-03-03 |
20160060353 | ANTI-HER2 ANTIBODY VARIANTS - The present invention concerns novel antibody variants, particularly anti-HER2 antibody variants having substitutions at positions within the variable domains of the heavy and light chains | 2016-03-03 |
20160060354 | SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES - The current disclosure provides binding polypeptides (e.g., antibodies), and targeting moiety conjugates thereof, comprising a site-specifically engineered glycan linkage within native or engineered glycans of the binding polypeptide. The current disclosure also provides nucleic acids encoding the antigen-binding polypeptides, recombinant expression vectors and host cells for making such antigen-binding polypeptides. Methods of using the antigen-binding polypeptides disclosed herein to treat disease are also provided. | 2016-03-03 |
20160060355 | METHODS FOR IMMUNE GLOBULIN ADMINISTRATION - Methods for administering immune globulin and devices for use thereof. The methods may generally include measuring a patient's hemolysis levels and determining whether the patient is suitable for immune globulin treatment, determining whether immune globulin treatment should be continued, and/or determining if the dose needs to be changed. | 2016-03-03 |
20160060356 | ANTI-FAP ANTIBODIES AND METHODS OF USE - The invention provides antibodies against Fibroblast Activation Protein (FAP) and methods of using the same. | 2016-03-03 |
20160060357 | ANTI-FAP ANTIBODIES AND METHODS OF USE - The invention provides antibodies against Fibroblast Activation Protein (FAP) and methods of using the same. | 2016-03-03 |
20160060358 | INDUCTION OF ANTIGEN-SPECIFIC TOLERANCE - Described are compositions and methods for the induction of an antigen-specific tolerance in a vertebrate. Also described are compositions and methods for the induction of antigen-specific tolerance using a fusion or a complex of the antigen (e.g., an antibody or an enzyme) against which tolerance is desired with a phosphatidylserine-binding domain derived from a phosphatidylserine-binding protein (including peptides). | 2016-03-03 |
20160060359 | Human Lambda Light Chain Mice - Genetically modified mice are provided that express human λ variable (hVλ) sequences, including mice that express hVλ sequences from an endogenous mouse λ light chain locus, mice that express hVλ sequences from an endogenous mouse κ light chain locus, and mice that express hVλ sequences from a transgene or an episome wherein the hVλ sequence is linked to a mouse constant sequence. Mice are provided that are a source of somatically mutated human λ variable sequences useful for making antigen-binding proteins. Compositions and methods for making antigen-binding proteins that comprise human λ variable sequences, including human antibodies, are provided. | 2016-03-03 |
20160060360 | RAPID CLEARANCE OF ANTIGEN COMPLEXES USING NOVEL ANTIBODIES - The present invention relates to rapid clearance molecules that bind target antigens and FcγRIIb with increased affinity as compared to parent molecules, said compositions being capable of causing accelerated clearance of such antigens. Such compositions are useful for treating a variety of disorders, including allergic diseases, atherosclerosis, and a variety of other conditions. | 2016-03-03 |
20160060361 | AMPHIPHILIC POLYMER - The present invention relates to an amphiphilic polymer which includes a large amount of hydrophilic structures and hydrophobic structures, and thereby effectively stabilizing a membrane protein having a hydrophobic surface in an aqueous solution. A method of preparing an amphiphilic polymer represented by Formula 1 includes reacting a poly-gamma-glutamic acid with a reaction product of a fluorescent dye, biotin, an alkyl carboxylic acid having 1 to 10 carbon atoms or a cycloalkyl carboxylic acid having 5 to 20 carbon atoms having a carboxyl group, and dicyclo-hexylcarbodiimide (DCC) and reacting the poly-gamma-glutamic acid with DCC after reacting the poly-gamma-glutamic acid with the reaction product, and reacting the poly-gamma-glutamic acid with a hydrophilic amine and a hydrophobic amine. | 2016-03-03 |
20160060362 | CHITOSAN-DERIVATIVE COMPOUNDS AND METHODS OF CONTROLLING MICROBIAL POPULATIONS - The present invention is directed to chitosan-derivative compounds and structures, methods of making chitosan-derivative compounds and methods for controlling, inhibiting and enhancing microbial populations in a variety of environments. The present invention is also directed to the control, inhibition and enhancement of microbial populations in animals, particularly humans. The microbial populations include bacteria, viruses and other pathogens where control of microbial populations are a necessity. The chitosan-derivative compounds of the present invention include chitosan-arginine compounds, related chitosan-L/D unnatural amino acid compounds, chitosan-acid amine compounds, chitosan-L/D natural amino acid derivative compounds, co-derivatives of the chitosan-derivative compounds, salts of the chitosan derivative compounds, and chitosan-guanidine compounds. | 2016-03-03 |
20160060363 | CHEMICAL PULPING OF CHITINOUS BIOMASS FOR CHITIN - Methods of separating chitin from a chitinous biomass that contains chitin and non-chitin material by a chemical pulping process that uses a protic ionic liquid or a composition comprising acid and base precursor molecules are described. Also described are methods for purifying chemically pulped chitin resulting in a pure chitin material with a high molecular weight and a higher degree of acetylation in comparison to traditional pulping and ionic liquid extraction based methods. | 2016-03-03 |
20160060364 | LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF - A low-molecular-weight fucosylated glycosaminoglycan (aTFG) containing 2,5-anhydrated talose, alditol, glycosylamine or N-substituted glycosylamine monosaccharide composition thereof, preparation method thereof, pharmaceutical compositions containing the aTFG, and use thereof for preventing and/or treating thrombotic diseases are provided. The aTFG has potent anticoagulant activity targeting at intrinsic coagulation factor Xase, and inhibiting thrombogenesis, and therefore can be used as drugs for preventing and/or treating cardiovascular and cerebrovascular diseases. | 2016-03-03 |
20160060365 | HEPARAN SULFATE SYNTHESIS - The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in numerous ways to produce a range of oligosaccharides. | 2016-03-03 |
20160060366 | POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION - Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided. | 2016-03-03 |
20160060367 | REFINED PRODUCT OBTAINED FROM RICE HULL AND PREPARATION PROCESS AND USE THEREOF - Disclosed herein is a refined product obtained from a rice hull, which consists essentially of a type II arabinogalactan having a number average molecular weight in the range of 56 to 103 kDa. Also disclosed are a process for producing the refined product and use of the refined product for enhancing the biological activity of innate immune cells, as well as for treating allergy and cancer. | 2016-03-03 |
20160060368 | Amino Silane-Modified Polymers - Modified macromolecular compounds obtainable by using specific amino silane polymerization initiator compounds and optionally chain end-modifying compounds are described. Polymer compositions including such modified macromolecular compounds and the use of such compositions in the preparation of vulcanized (crosslinked) elastomeric polymer compositions and articles are described. | 2016-03-03 |
20160060369 | SLURRY PHASE POLYMERISATION PROCESS - A process comprising polymerizing in a loop reactor an olefin monomer optionally together with an olefin commoner in the presence of a polymerisation catalyst in a diluent to produce a slurry comprising solid particulate olefin polymer and the diluent wherein the Froude number is maintained at or below 20 is disclosed. | 2016-03-03 |
20160060370 | SOLID CATALYST COMPONENT, CATALYST COMPRISING SAID SOLID COMPONENT, AND PROCESS FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS - A solid catalyst component for the (co)polymerization of α-olefins having general formula (I): | 2016-03-03 |
20160060371 | PROPYLENE COPOLYMER WITH HIGH IMPACT PROPORTIES - Monophasic propylene copolymer with high stiffness and impact resistance. | 2016-03-03 |
20160060372 | SUPPORTED DONOR MODIFIED ZIEGLER-NATTA CATALYSTS - Procatalyst comprising an inorganic support, a chlorine compound carried on said support, a magnesium compound carried on said support, a titanium compound carried on said support, and a compound comprising two oxygen containing rings, wherein said two rings are linked via a bridge selected from the group consisting of carbon bridge, silicon bridge, ethane-1.2-diyl bridge, ethene-1,2-diyl bridge, alkylaminomethyl bridge and imine bridge. | 2016-03-03 |
20160060373 | AN ETHYLENE/ALPHA-OLEFIN INTERPOLYMER COMPOSITION - An ethylene/alpha-olefin interpolymer composition suitable for pipe applications prepared via solution polymerization process, and pipes made therefrom. The ethylene/alpha-olefin interpolymer composition suitable for pipe applications according to the present invention comprises greater than 80 percent by weight of units derived from ethylene and 20 percent or less by weight of units derived from one or more alpha olefin co-monomers, wherein said ethylene/alpha-olefin interpolymer has a density in the range of from 0.925 to 0.935 g/cm | 2016-03-03 |
20160060374 | MONOMER HAVING N-ACYL CARBAMOYL GROUP AND LACTONE SKELETON, AND POLYMERIC COMPOUND - Disclosed is a monomer containing an N-acylcarbamoyl group and a lactone skeleton. The monomer is exemplified by Formula (1): | 2016-03-03 |
20160060375 | TULIPALIN A-BASED HYDROXYL-FUNCTIONALIZED POLYMERS, AND ENGINEERED MATERIALS PREPARED THEREFROM - A Tulipalin A-based hydroxyl-functionalized (hf) polymer is synthesized by converting, via a ring opening reaction, poly(Tulipalin A) or poly(Tulipalin A-co-acrylic) in the presence of a nucleophilic monomer and a catalyst. The nucleophilic monomer may be, for example, a nitrogen-containing monomer such as Dimethylamine. The poly(Tulipalin A) or the poly(Tulipalin A-co-acrylic) may be prepared, for example, via free radical polymerization using an initiator such as AIBN. Any suitable free radically copolymerizable monomer, such as N,N-Dimethylmethacrylamide, may be used in the preparation of the poly(Tulipalin A-co-acrylic). In some embodiments, an engineered material is prepared from the Tulipalin A-based hydroxyl-functionalized polymer using hydroxyl groups present therein as synthetic handles through which a plethora of useful properties can be directly engineered into the material. | 2016-03-03 |
20160060376 | FLUORINE-CONTAINING, SILICON-CONTAINING POLYMER AND SURFACE TREATMENT AGENT - The present invention provides a fluorine-containing and silicon-containing polymer of the general formula (A) or (B) (wherein each symbol is as defined in the description) which is useful for forming a surface treatment layer having water-repellency, oil-repellency and antifouling property and excellent surface slip property. | 2016-03-03 |
20160060377 | NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS - Polyimides containing a backbone with at least one nanoparticle component and made from oligomers having endcaps that are difunctional or a mix of di- and monofunctionality are provided. The endcaps may be nadic or phenylethynyl. The backbone may be wholly inorganic or made from a mixture of inorganic and organic groups. The oligomers may be created in-situ using standard polymerization of monomeric reactants chemistry using a solvent or may be provided as a pre-imidized compound that may be either a solid or liquid. It is believed that the nanoparticle component of the polymer backbone provides superior thermo-oxidative stability verses unmodified organic backbones. It is further believed that providing difunctional or a mixture of di- and monofunctional endcaps allows for increased crosslinking to provide improved strength and stiffness verses wholly monofunctional endcapped oligomers for polyimides. The nanoparticle is part of the backbone of the polymer and not solely a pendant group. | 2016-03-03 |
20160060378 | METHOD FOR PRODUCING PROPYLENE POLYMERIC MATERIAL - A method is provided for producing a propylene polymeric material containing a propylene polymer component high in content of α-olefin units. The material can be produced stably without stopping of the operation due to clogging of a pipe. The method is one for producing a propylene polymeric material composed of a propylene polymer component (A) and a propylene polymer component (B) via at least two steps, including a first step of producing the component (A) and a second step of producing the component (B) in a gas phase. The partial pressure of the α-olefin having four or more carbon atoms in the gas phase in the second step reactor is 0.10 MPa or more. A formula, X≦0.0025×Y+0.2850, is satisfied, wherein the partial pressure is X MPa, and the content of the propylene polymer component (A) in the propylene polymeric material is Y % by weight. | 2016-03-03 |
20160060379 | PARTICLES FOR ELECTROPHORETIC DISPLAYS - This invention relates to polymer particles, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, electrophoretic displays comprising such particle, and new copolymer stabilisers. | 2016-03-03 |
20160060380 | HYDROPHILIC POLYASPARTIC ESTERS - Disclosed are polyaspartic esters obtainable by reaction of at least one polyamine component A), comprising an amine compound of the formula (I), | 2016-03-03 |
20160060381 | POLYURETHANE RESIN FOR MOISTURE-PERMEABLE WATER-PROOF MATERIALS, AND POLYURETHANE RESIN COMPOSITION - The present invention aims to provide a polyurethane resin for moisture-permeable waterproof materials which is excellent in all of the moisture permeability, waterproofness, and resistance to washing. The polyurethane resin for moisture-permeable waterproof materials according to the present invention is a polyurethane resin for moisture-permeable waterproof materials, obtainable by reacting an active hydrogen component (A1) with an organic polyisocyanate component (B),
| 2016-03-03 |
20160060382 | SILYL TERMINATED PREPOLYMERS, METHOD FOR MAKING THEM AND ADHESIVE COMPOSITIONS MADE THEREFROM - An improved silane modified polymer useful in adhesive compositions is made from a silane precursor material made by a process comprising reacting an organic compound having a backbone that is terminated by an amino group having at least one active amino hydrogen and a hydrolysable silane, wherein the backbone is comprised of at least one secondary amino group having one active amino hydrogen and a Michael addition acceptor compound, wherein the Michael addition compound fails to have a group reactive with an isocyanate group to form the silane precursor compound. The silane precursor compound is reacted with an isocyanate terminated polyurethane prepolymer to form a silane modified prepolymer. The silane modified prepolymer may then be cured with moisture and may be employed in an adhesive composition containing other components such as a plasticizer, catalyst and filler. | 2016-03-03 |
20160060383 | EPOXY RESIN COMPOSITIONS - A novel epoxy resin composition capable of forming a coating composition with a high volume solids content; a coating composition comprising such novel epoxy resin composition capable of providing a resultant coating films with balanced properties including good flexibility, good chemical resistance, short dry-hard time, desirable hardness, and good anti-corrosion performance; and the process of preparing the compositions. | 2016-03-03 |
20160060384 | MODIFIED PHENOLIC RESIN, METHOD FOR PRODUCING MODIFIED PHENOLIC RESIN, MODIFIED EPOXY RESIN, METHOD FOR PRODUCING MODIFIED EPOXY RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT OF SAME, AND PRINTED WIRING BOARD - Provided are a modified epoxy resin and a modified epoxy resin whose cured products exhibit good heat resistance and dielectric properties, methods for producing these, a curable resin composition, a cured product of the curable resin composition, and a printed wiring substrate. A modified phenolic resin comprises a phenolic resin structure (A), wherein at least one aromatic nucleus (a) in the phenolic resin structure (A) has, as a substituent, a structural segment (1) represented by structural formula (1) below: | 2016-03-03 |
20160060385 | POLYESTER - The present invention relates to a process for producing polyester, which method comprises reacting a dicarboxylic acid and a diol in the presence of a trizazine derivative, such as melamine-cyanuric acid (MeCy). The invention also relates to process for producing a polyester, which method comprises reacting a dicarboxylic acid and a diol in the presence of a metal sulfate. | 2016-03-03 |
20160060386 | PROCESSING HYDROXY-CARBOXYLIC ACIDS TO POLYMERS - Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful intermediates and products, such as aliphatic hydroxy-carboxylic acid and hydroxyl-carboxylic acid derivatives. These aliphatic hydroxy-carboxylic acids are, in turn, polymerized. The polymerization is carried out using a thin film evaporator or a thin film polymerization/devolatilization device. Conversion of lactic acid to poly lactic acid is an especially useful product to this process. | 2016-03-03 |
20160060387 | GLYCOLIC ACID POLYMERS AND METHOD OF PRODUCING THE SAME - Described herein is a feasible, significantly simplified production method that avoids challenging lactonization steps and converts a low molecular weight aliphatic polyester, consisting of hydroxy acids and a comonomer, whose molecular weight has been increased by step-growth polymerization reactions. The molecular weight of the aliphatic polyester, based on comparison of initial and final weight average molecular weights (M | 2016-03-03 |
20160060388 | PROCESS FOR PRODUCING A LACTIC ACID-GLYCOLIC ACID COPOLYMER OR A SALT THEREOF - Provided is a purified lactic acid-glycolic acid copolymer, preferably in the form of powder, having a reduced content of dimers such as residual lactide and glycolide that can be produced by a simple industrial process without the use of any high-shear special device. Further provided is a high-purity lactic acid-glycolic acid copolymer which has small amounts of dimers such as residual lactide and glycolide and small amounts of a low-molecular weight lactic acid-glycolic acid copolymer or a salt thereof and which has a small ratio of weight average molecular weight to number average molecular weight (Mw/Mn). The copolymer can be produced in accordance with a defined process. | 2016-03-03 |
20160060389 | Composition crosslinkable by Real Michael Addition (RMA) reaction - The present invention relates to a crosslinkable composition crosslinkable by Real Michael Addition (RMA) reaction comprising a component with at least 2 activated unsaturated groups (hereafter referred to as the RMA acceptor groups) and a component with at least 2 acidic protons C—H in activated methylene or methane groups (hereafter referred to as the RMA donor groups) which components can react to form a crosslinked network. | 2016-03-03 |
20160060390 | BRANCHED POLYESTER RESINS AND EASY TO CLEAN COATINGS COMPRISING THE SAME - An uncured, branched polyester resin prepared by free radical polymerization of unsaturated polyester prepolymers, wherein the polymerization occurs primarily by reaction of the unsaturation, is disclosed. Coatings comprising the same are also disclosed, as are substrates coated at least in part with such coatings. | 2016-03-03 |
20160060391 | COPOLYMER BASED ON DIMETHYL CARBONATE AND METHOD OF PREPARING THE SAME - A copolymer based on dimethyl carbonate and a method of preparing the same are provided. The copolymer based on dimethyl carbonate has a unit from dimethyl carbonate, diols, and a modification monomer. The copolymer based on dimethyl carbonate can be obtained by proceeding transesterification and polycondenastion. | 2016-03-03 |
20160060392 | BIODEGRADABLE NETWORK POLYMERS FOR REGENERATIVE MEDICINE AND TISSUE ENGINEERING - The disclosure relates to biodegradable polyether network polymers crosslinked via ester linkages, to substrates, implants and scaffolds comprising the biodegradable polyether network polymers, to methods for preparing such network polymers, implants and scaffolds, and to methods of using substrates, implants and scaffolds comprising the network polymers, particularly for culturing cells and regenerating tissue. | 2016-03-03 |
20160060393 | POLYARYLENE MATERIALS - Certain polyarylene oligomers having improved solubility are useful in forming dielectric material layers in electronics applications. | 2016-03-03 |
20160060394 | LOW DIELECTRIC CONSTANT POLYMER CONTAINING DINAPHTHYL AND HEXAFLUOROCYCLOBUTYL ETHER UNIT, PREPARATION METHOD AND USE - The present invention belongs to the field of preparation of high performance polymers, and specifically relates to a low dielectric constant polymer containing dinaphthyl and hexafluorocyclobutyl ether units, and preparation method and use thereof. The polymer is prepared as follows: under the effect of an alkali, 1-naphthol bromotetrafluoroethane ether is prepared from 1-naphthol and tetrafluorodibromoethane in an organic solvent, and then reduced by a zinc powder so as to obtain 1-naphthol trifluorovinyl ether. 1-naphthol trifluorovinyl ether is treated at a high temperature to obtain a bisnaphthol hexafluorocyclobutyl ether monomer. The monomer is subjected to oxidative coupling in the presence of ferric trichloride so as to obtain a thermal polymer containing dinaphthyl and hexafluorocyclobutyl structural units with a good film-forming property, and in a nitrogen atmosphere, the temperature for 5% weight loss (T | 2016-03-03 |
20160060395 | METHODS AND SYSTEMS FOR THE RECOVERY OF WATER FROM A POLYAMIDE SYNTHESIS PROCESS - The present disclosure relates to systems and methods for manufacturing a polyamide. The method can include obtaining, from a reservoir, an aqueous solution comprising a dicarboxylic acid, a diamine, and water having a substantially liquid phase; concentrating the aqueous solution including transforming a portion of the water having a substantially liquid phase to water having a substantially gaseous phase; condensing the water having a substantially gaseous phase into condensed water having a substantially liquid phase; removing at least one impurity from at least one of the condensed water having a substantially liquid phase and the water having a substantially gaseous phase to produce cleaned water having a substantially liquid phase; and reusing the cleaned water having a substantially liquid phase. The system can include, among other things, a reservoir; an evaporator assembly, in fluid communication with the reservoir; a condensation assembly, in fluid communication with the evaporator assembly; a collection assembly; and a conduit network. | 2016-03-03 |
20160060396 | POLYMERS, THEIR METHOD OF MANUFACTURE AND USE THEREOF - A method for the manufacture of a polymer is provided, the method comprising:
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20160060397 | METHOD FOR PRODUCING POLYARYLENE SULFIDE RESIN AND POLYARYLENE SULFIDE RESIN COMPOSITION - A problem is to provide a method for producing a polyarylene sulfide resin having excellent reactivity to other compounds and resins, such as an impact resistance improver such as an epoxysilane coupling agent, a functional group-containing thermoplastic elastomer, or the like, and also provide a polyarylene sulfide resin composition produced by the production method, not containing chlorine atoms, and having the excellent reactivity. A method for producing a polyarylene sulfide resin includes performing polymerization reaction of a mixture containing a diiodo aromatic compound, a sulfur compound, and a polymerization inhibitor having a specified functional group. The problem can be solved by using a polyarylene sulfide resin composition containing a polyarylene sulfide resin having a specified terminal functional group and iodine atoms within a range of 0.01 to 10,000 ppm relative to the polyarylene sulfide resin. | 2016-03-03 |
20160060398 | METHOD OF MANUFACTURING CATIONIC POLYMERIZATION RESIN WITH ENHANCED UV STABILITY AND CATIONIC POLYMERIZATION RESIN MANUFACTURED BY THE SAME - The present invention relates to a cured product with excellent UV stability, which is manufactured using a resin composition containing a cation polymeric resin capable of cationic polymerization and a photostable cationic polymerization initiator in the form of an iodonium salt without adding an additional photoinitiator, and a method of manufacturing the cured product. | 2016-03-03 |
20160060399 | POLYORGANOSILOXANE AND POLYCARBONATE-POLYORGANOSILOXANE COPOLYMER - Provided is a polyorganosiloxane having a platinum content of 1 ppm by mass or less. | 2016-03-03 |
20160060400 | NANOMODIFIED BACKBONES FOR POLYIMIDES WITH DIFUNCTIONAL AND MIXED-FUNCTIONALITY ENDCAPS - Polyimides containing a backbone with at least one nanoparticle component and made from oligomers having endcaps that are difunctional or a mix of di- and monofunctionality are provided. The endcaps may be nadic or phenylethynyl. The backbone may be wholly inorganic or made from a mixture of inorganic and organic groups. The oligomers may be created in-situ using standard polymerization of monomeric reactants chemistry using a solvent or may be provided as a pre-imidized compound that may be either a solid or liquid. It is believed that the nanoparticle component of the polymer backbone provides superior thermo-oxidative stability verses unmodified organic backbones. It is further believed that providing difunctional or a mixture of di- and monofunctional endcaps allows for increased crosslinking to provide improved strength and stiffness verses wholly monofunctional endcapped oligomers for polyimides. The nanoparticle is part of the backbone of the polymer and not solely a pendant group. | 2016-03-03 |
20160060401 | Fire Retardant Materials and Devices Including Same - This document provides fire retardant materials, including polymers that include pyridinium salt moieties, or a combination thereof, and phosphine oxide moieties. In some cases, fire retardant polymers provided herein have the following structure: | 2016-03-03 |
20160060402 | FORMED BODY HAVING A LAYER OF THERMOPLASTIC RESIN - A formed body having a layer of a resin composition constituted by a thermoplastic resin and a barrier resin, wherein the layer of the resin composition forms, in a matrix of the thermoplastic resin, a layer structure in which the barrier resin is dispersed in the form of a lamellar dispersion phase stretching in one direction; and the ratio (a)/(b) of an aspect ratio (a) of the dispersion phase of the barrier resin near the surfaces of the layer and an aspect ratio (b) of the dispersion phase of the barrier resin in the central portion in the direction of thickness of the layer, is not more than 2.0. The formed body has the layer of the resin composition constituted by the thermoplastic resin and the barrier resin, and has a dispersion structure capable of exhibiting excellent barrier property despite of the single layer. | 2016-03-03 |
20160060403 | POLYCARBONATE FILMS FOR CAPACITORS, METHODS OF MANUFACTURE, AND ARTICLES MANUFACTURED THEREFROM - A film comprises a phthalimidine copolycarbonate comprising first repeating units and second repeating units different from the first repeating units, wherein the first repeating units are phthalimidine carbonate units | 2016-03-03 |
20160060404 | POLYIMIDE FILM ARRANGEMENT, AND MANUFACTURE AND ASSEMBLY THEREOF - A polyimide film arrangement (e.g., a polyimide film) includes a polyimide layer having a first and a second surface opposite to each other, and a base layer peelably adhered to the first surface of the polyimide layer and containing a polyimide. The polyimide layer or the base layer includes a filler having a surface energy less than about 35 dyne/cm. Moreover, the present application also describes a method of fabricating the polyimide film arrangement, and its assembly on a substrate. | 2016-03-03 |
20160060405 | POLYMER FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE - The polymer film comprises a carbonyl bond-containing polymer and a compound having δh of equal to or higher than 11.0 and δχ of equal to or lower than 1.50, wherein the δh is a value of hydrogen-bonding capacity calculated by Hoy method and the δχ is a value calculated by equation 1: | 2016-03-03 |
20160060406 | CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE - The cellulose acylate film includes a compound denoted by formula 1 below: | 2016-03-03 |
20160060407 | PROPYLENE BASED RESIN COMPOSITION AND USE THEREOF - Means for solving the problems | 2016-03-03 |
20160060408 | DRY FILM AND PRINTED WIRING BOARD - An object of the present invention is to provide: a dry film comprising a resin layer which has excellent detachability from a carrier film and in which cracking and powdering are inhibited; and a printed wiring board comprising a cured article obtained by curing the dry film. The dry film comprises a resin layer containing a thermosetting resin component, a filler and at least two solvents, wherein the at least two solvents both have a boiling point of 100° C. or higher and the boiling points of the at least two solvents are different by not less than 5° C. | 2016-03-03 |
20160060409 | OPTICAL FILM AND DISPLAY DEVICE INCLUDING SAME - An optical film including a polymer including a repeating unit A including a repeating unit represented by the following Chemical Formulas 1 to 3, or a combination thereof; and a repeating unit B derived from a monomer having an unsaturated bond copolymerizable with the repeating unit A, wherein the optical film has a short wavelength dispersion of an in-plane phase-difference value (R | 2016-03-03 |
20160060410 | PATTERN FORMING METHOD - A pattern is formed by forming a first pattern on a first film, forming a block copolymer layer including a first block chain and a second block chain on the first pattern, forming a second pattern, forming a second film on the second pattern, selectively removing the second film until the second pattern is exposed, forming a third pattern, and processing the first film using the third pattern as a mask. The second pattern is formed by microphase-separating the block copolymer layer, and removing the first block chain or the second block chain. The second film is formed by applying a material having an etch rate that is less than an etch rate of a material of the first pattern and the second pattern. The third pattern is formed by selectively removing the second pattern and the first pattern using the second film as a mask. | 2016-03-03 |
20160060411 | CABLE AND POLYMER COMPOSITION COMPRISING A MULTIMODAL ETHYLENE COPOLYMER - The present invention relates to a cable comprising a conductor surrounded by one or more layers, wherein at least one layer comprises a polymer composition comprising a copolymer of ethylene with one or more comonomers, to a process for producing the cable and to a polymer composition suitable as a cable layer material. | 2016-03-03 |
20160060412 | BIODEGRADABLE FOAMED MATERIAL - A biodegradable foamed material is formed from corn meal, corn flour and distillers grains, especially dried distillers grains with solubles (DDGS). The foamed material has a low density and is cheaper to produce, has a more pleasing color and may be formed faster and into larger pellets than packaging material formed from corn meal without corn flour and distillers grains. The foamed material is useful in packaging, as insulation and the like. | 2016-03-03 |
20160060413 | MOLDED BODY OF COMPOSITE RESIN FOAM - A composite resin expanded molded article comprising: 100 parts by mass of an ethylene-vinyl acetate copolymer; and 100 to 400 parts by mass of a polystyrene-based resin, wherein the composite resin expanded molded article has an average cell diameter D of 100 to 500 μm and an average cell membrane thickness T of 1 to 5 μm. | 2016-03-03 |
20160060414 | Thermoformed foam articles - A method for manufacturing a thermoformed a polyetherimide/poly(biphenyl ether sulfone) foam article which comprises following three steps:
| 2016-03-03 |
20160060415 | PROCESSES FOR PREPARING FOAM COMPOSITES - Processes for preparing polystyrene-phenolic foam composites and precursor compositions are described. The processes yield composites having advantageous properties useful in insulation and fire resisting applications. | 2016-03-03 |
20160060416 | HIGH ALCOHOL CONTENT FOAMING COMPOSITIONS WITH SILICONE-BASED SURFACTANTS - This invention relates to a “high lower alcohol content”(>40% v/v of a C | 2016-03-03 |
20160060417 | METHOD FOR PRODUCING EXPANDABLE GRANULATES CONTAINING POLYLACTIC ACID - The invention relates to a process for producing expandable pelletized material which comprises polylactic acid which comprises the following steps:
| 2016-03-03 |
20160060418 | PARTICULATE SUPERABSORBENT POLYMER COMPOSITION HAVING IMPROVED STABILITY AND FAST ABSORPTION - The present invention relates to a fast particulate superabsorbent polymer composition comprising a polymer comprising a neutralized aluminum salt solution applied to the surface of a particulate superabsorbent polymer; wherein an aqueous solution of the neutralized aluminum salt has a pH value from about 5.5 to about 8; and subsequent to subjecting the particulate superabsorbent polymer composition to the Processing Test, the particulate superabsorbent polymer composition has a permeability stability index of from about 0.60 to about 0.99, and a compressibility from 1.30 mm | 2016-03-03 |
20160060419 | METHODS AND MATERIALS FOR DEPOLYMERIZING POLYESTERS - Provided is a method of depolymerizing polyesters from post-consumer products, such as beverage bottles, to produce a high purity reaction product. For the depolymerization reaction, the polyesters are reacted with an alcohol and an amine organocatalyst at a temperature of about 150° C. to about 250° C. In one application, the use of an organocatalyst with a boiling point significantly lower than the boiling point of the reactant alcohol allows for the ready recycling of the amine organocatalyst. In another application, performing the depolymerization reaction under pressure at a temperature above the boiling point of the alcohol allows for accelerated depolymerization rates and the recovery of the organocatalyst with no further heat input. In a further application, glycolytic depolymerization of poly(ethylene terephthalate) (PET) produces a reaction product of bis(2-hydroxyethyl)terephthalate (BHET), which may in turn be used to produce high purity beverage bottle grade PET, in a closed loop process with minimal waste. | 2016-03-03 |
20160060420 | TIRE WITH CARBON BLACK REINFORCED POLYURETHANE - This invention relates to a vehicular tire containing at least one carbon black reinforced polyurethane component. | 2016-03-03 |
20160060421 | CHEMICAL COMPOSITION FOR DUST SUPPRESSION AND SOIL STABILIZATION - A chemical composition for dust suppression and soil stabilization includes a mixture of water-based asphalt emulsion and magnesium chloride solution. | 2016-03-03 |
20160060422 | POLYMER PARTICLES ADSORBED TO SULFATE-PROCESS TITANIUM DIOXIDE - Provided is an aqueous dispersion of particles of sulfate-process titanium dioxide, wherein polymeric particles are adsorbed onto said particles of titanium dioxide, wherein said polymeric particles comprise polymerized units of one or more P-acid monomer. | 2016-03-03 |
20160060423 | MIXTURE COMPRISING POLYOLEFIN PARTICLES AND FIBROUS BASIC MAGNESIUM SULFATE AGGREGATED PARTICLES - A resin composition having high compositional uniformity can be advantageously prepared in industry by depositing a mixture comprising polyolefin particles and fibrous basic magnesium sulfate aggregated particles which satisfies the condition that a value resulting from calculation of formula of D | 2016-03-03 |