11th week of 2009 patent applcation highlights part 52 |
Patent application number | Title | Published |
20090069494 | Polymer material - A process is described for providing a polymer material by blending as a first component one or more hydrophilic polymers, and as a second component one or more neutralising chemicals, in the complete or substantial absence of water. In the absence of water, the components will not be aqueous solutions. Thus the components can be used in blending processes, and the present invention is able to form many other shapes and forms of material other than laminates on substrates. | 2009-03-12 |
20090069495 | Coating Compositions Having High Weathering Resistance, Process for Preparation Thereof and Use Thereof - What are described are coating compositions comprising pigments and/or fillers and multistage polyvinyl ester dispersions as binders. These binders are produced by a selected multistage process in which a polyvinyl ester dispersion is obtained in a first stage, monomers in dissolved or pure form or in the form of an emulsion are added to the reaction mixture in a second stage and then the polymerization is started again. The polyvinyl ester dispersions comprise polymerized silanes and/or epoxides or the polyvinyl ester dispersions have only a small content of protective colloids, if any. The coating compositions formulated with the multistage polyvinyl ester dispersions obtained in this way are notable for a very high weathering resistance. | 2009-03-12 |
20090069496 | COHERENT GEL COATING FOR PREVENTING AND/OR EXTINGUISHING FIRES - A method for applying water-laden polymer to a surface to prevent and/or extinguish a fire, the method comprising the steps of dispersing a dry, ground, superabsorbent polymer comprising particles of 20 microns or less in diameter to water in an amount sufficient to form a coherent polymer gel, and directing the coherent polymer gel onto a surface to prevent and/or extinguish a fire. | 2009-03-12 |
20090069497 | Polyurethane/Urea Containing Pendant Alkoxysilane Groups - The present invention relates to polyurethane/ureas wherein the polyurethane/ureas contain 0.5 to 6% by weight, based on the weight of the polyurethane/ureas, of alkoxysilane groups (calculated as Si, MW 28), which have been incorporated by the reaction of isocyanate groups with a dihydroxy compound containing urea and alkoxysilane groups, and wherein the polyurethane/ureas optionally contain hydrophilic groups and are optionally dispersed in an aqueous medium. | 2009-03-12 |
20090069498 | GRIND RESIN - A grind resin, a pigment dispersion, and a coating composition are provided. The grind resin comprises a reaction product of a dibasic acid, optionally a polybasic acid, a diol, optionally a polyol, and a fatty compound. The fatty compound has a fatty chain and two reactive groups reactive with at least one of the dibasic acid and the diol provided that ≦5% of all acid groups are provided by the polybasic acid and <20% of all hydroxyl groups are provided by the polyol. The reaction product is substantially free from branching comprising the reaction product of acid groups or hydroxyl groups and the dibasic acid, polybasic acid, diol, polyol, or fatty compound. The pigment dispersion comprises a pigment and the grind resin. The coating composition comprises a vehicle resin, the pigment, the grind resin, and a cross-linking agent reactive with the vehicle resin and/or the grind resin. | 2009-03-12 |
20090069499 | PROCESS FOR PRODUCING GLASS FIBER-REINFORCED POLYAMIDE RESIN COMPOSITION - The present invention provides a process for producing a polyamide resin composition, comprising the steps of: impregnating a molten polyamide resin into glass fiber rovings; taking off the polyamide-impregnated glass fiber rovings during twisting thereof to provide a strand; and pelletizing the strand to provide a resin composition, wherein a melt viscosity of the polyamide resin is set to fall within a particular range. According to the present invention, there can be provided a process for producing a glass fiber-reinforced polyamide resin composition excellent in the impregnation of the resin into the glass fiber rovings and capable of offering a molding excellent in mechanical strength and color tone. | 2009-03-12 |
20090069500 | Label target and labeling reagents comprising rigid group backbones - This invention provides for labeling reagents, labeled targets and processes for preparing labeling reagents. The labeling reagents can take the form of cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes. These labeling reagents are useful for labeling probes or targets, including nucleic acids and proteins. These reagents can be usefully applied to protein and nucleic acid probe based assays. They are also applicable to real-time detection processes. | 2009-03-12 |
20090069501 | METHOD OF MAKING AN ALKOXYLATED POLYETHYLENIMINE PRODUCT - A method of making an alkoxylated polyethyleneimine (APEI) product having reduced discoloration includes treating a composition including a component selected from the group of polyethyleneimine (PEI), APEI intermediate, and combinations thereof that is used to make the APEI product. The method of treating the composition includes heating a composition that includes an adduct of a conjugate base and PEI, water, and the component at a temperature of from 158 to 338° F. for a period of at least three hours in the absence of additional water in order to substantially decompose the adduct in the composition. The aqueous solutions of APEI product thus made have Gardner color values of less than 6. | 2009-03-12 |
20090069502 | CROSS-LINKABLE COMPOUNDS COMPRISING A PERFLUOROPOLYETHER MOIETY - The invention pertains to a cross-linkable compound comprising a perfluoropolyether (PFPE) moiety derived from an hydroxy-terminated PFPE-oil, which is bonded through a spacer with an ethylenically unsaturated group, wherein the spacer extends over at least three carbon atoms. The invention further relates to a perfluoropolyether rubber obtainable by hydrosilating said cross-linkable compound and to an apparatus for transferring a toner image from an image-forming medium to a receiving medium. | 2009-03-12 |
20090069503 | SULFUR-CONTAINING CYCLIC OLEFIN RESIN AND ITS PRODUCTION METHOD - An object of the present invention is to provide a novel sulfur-containing cyclic olefin resin having high transparency and high refractive index and being expected to utilization to optical materials such as various plastic lenses represented by a condensing lens, prism sheets, antireflective films, transparent coating materials such as an optical fiber coating material, optical films and the like, and its production method. | 2009-03-12 |
20090069504 | Furanone-Initiated Polymers - Polymers initiated with furanones and compositions containing such polymers are suitable for use in making textiles, medical devices, delivery agents, packaging materials, coatings for such items, and the like. | 2009-03-12 |
20090069505 | CURABLE COMPOSITION - An object is to provide a curable composition having a good curability by use of an organotin-free catalyst, and the object is solved by a curable composition, comprising: (A) a polymer having a silicon group which can be crosslinked through formation of a siloxane bond, (B) fluorosilanes represented by general formula (1): R | 2009-03-12 |
20090069506 | HYDROPHILIC FILM, AND PLANOGRAPHIC PRINTING MATERIAL, STAIN-PREVENTATIVE MEMBER AND DEFOGGING MEMBER USING THE SAME - The invention provides a hydrophilic film obtained by curing, by at least one energy source selected from heat and light, a composition comprising a compound that has, in a molecule thereof, two or more ring structures selected from the group consisting of five-membered structures and six-membered structures, wherein the ring structures have a hydrophilic group. The invention further provides a planographic printing material having at least a substrate and the hydrophilic film formed on the substrate. The invention further provides a method for forming a planographic printing plate including at least forming an ink receiving portion on a planographic printing material by applying a hydrophobic material by an ink jet recording process. | 2009-03-12 |
20090069507 | Aromatic Polyimide Composition - Blend (B) comprising:
| 2009-03-12 |
20090069508 | POLYIMIDE POLYMER WITH OLIGOMERIC SILSESQUIOXANE - A soluble polyimide polymer with tethered oligomeric silsesquioxane compounds is produced using efficient, gentle reactions. A carboxylic acid attachment point on the polymer backbone is used to connect the oligomeric silsesquioxane. The oligomeric silsesquioxane compound includes an amine or an alcohol on an organic tether, which reacts with the carboxylic acid attachment point to produce either an amide or an ester bond. The amide or ester bond includes a carbonyl carbon directly connected to a phenyl group in the polymer backbone. The resultant polyimide polymer has many beneficial properties. | 2009-03-12 |
20090069509 | Poly (hydroxyalkanoic acid) compositions with improved toughness, dimensional stability and stretchability - Disclosed are poly(hydroxyalkanoic acid) compositions comprising a poly(hydroxyalkanoic acid), an ethylene ester copolymer, and an aliphatic carboxylic acid amide. | 2009-03-12 |
20090069510 | Cationic electrodeposition paint compositions - This invention discloses cationic electrodeposition paint compositions which comprise specific amino group-containing modified epoxy resin, specific xylene-formaldehyde resin-modified, amino group-containing epoxy resin and blocked polyisocyanate curing agent at specific blend ratios, and which can form coating film of excellent film thickness retention, finished appearance and electrocoatability on galvanized alloy steel sheet and of good corrosion resistance, even when the amount of volatile organic compound in the cationic electrodeposition paint is reduced. | 2009-03-12 |
20090069511 | Polyarylene Composition and Articles Made Therefrom - Polyarylene compositions comprising polyarylenes of two different specific types offering an exceptionally high level of strength and stiffness as well as improved properties such as elongability, impact resistance and fire resistance. Articles or a part thereof made from such polyarylene compositions and in particular those selected from the group consisting of films, fibers, coatings and membranes. | 2009-03-12 |
20090069512 | COMPOSITION AND ASSOCIATED METHOD - A composition includes a reaction product of a poly(arylene ether) composition having a plurality of terminal groups and a siloxane composition. Associated article and method are also provided. | 2009-03-12 |
20090069513 | EPOXY RESIN, METHOD FOR PRODUCING SAME AND USE THEREOF - An object of the present invention is to provide a multifunctional epoxy resin that is in a liquid state and that has a multifunctional structure. The multifunctional epoxy resin can be used as a reactive diluent and also used for a wide range of applications such as a molding material, a casting material, a laminating material, a paint, an adhesive, and a resist. The epoxy resin of the present invention is produced by glycidylation of dipentaerythritol represented by formula (1): | 2009-03-12 |
20090069514 | PRODUCTION METHOD OF OPTICAL TRANSMISSION MEDIUM - A polymerization initiator, a first polymerizable compound, and a second polymerizable compound are poured into a hollow of a first member ( | 2009-03-12 |
20090069515 | Solid Titanium Catalyst Component, Catalyst for Polymerization of Olefin and Process for Producing Olefin Polymer - A solid titanium catalyst component (I) of the present invention is characterized in that it contains titanium, magnesium, halogen, and a cyclic ester compound (a) represented by the following formula (1): | 2009-03-12 |
20090069516 | CATALYST SYSTEMS AND THEIR USE FOR METATHESIS REACTIONS - Novel catalyst systems for metathesis reactions, in particular for the metathesis of nitrile rubber, which contain a specific salt additive in addition to the metathesis catalyst are provided. | 2009-03-12 |
20090069517 | LIGANDS AND CATALYST SYSTEMS FOR THE OLIGOMERIZATION OF OLEFINIC MONOMERS - The present invention relates to ligands and catalyst systems and a process for the simultaneous trimerization and tetramerization of olefinic monomers using said ligands, the ligands having the general formula (I): | 2009-03-12 |
20090069518 | Process for the polymerization of 1-butene - A process for polymerizing 1-butene comprising the step of contacting under polymerization conditions 1-butene and optionally from 0 to 20% by mol of an alpha olefin with a catalyst system obtainable by contacting a bridget metallocene compound of formula (I) wherein R | 2009-03-12 |
20090069519 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS - Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins. | 2009-03-12 |
20090069520 | CATALYSTS FOR RADICAL POLYMERIZATION - Provided is a method for polymerizing a polymer precursor, comprising: contacting a polymer precursor with a lithium carborane catalyst and an initiator under polymerizing conditions. A reaction solvent may be used, but is not necessary. Also provided is a method of preparing lithium carborane polymers, comprising: contacting a lithium carborane polymer precursor having a terminal alkenyl or alkynyl group with an initiator and an optional reaction solvent under polymerizing conditions. Functionalized carborane anions are also provided. | 2009-03-12 |
20090069521 | Novel Compound, Polymer, and Radiation-Sensitive Composition - A radiation-sensitive resin composition is provided which has high transparency to radiation, excelling in basic properties as a resist such as sensitivity, resolution, and pattern shape, and, in particular, a high resolution radiation-sensitive resin composition providing a wide DOF and excelling in LER. Also provided are a polymer which can be used in the composition and a novel compound useful for synthesizing the polymer. The novel compound is shown by the following formula (2), | 2009-03-12 |
20090069522 | HYDROPHOBICALLY MODIFIED POLYMERS - This invention pertains to composition comprising one or more hydrophobically modified polyacrylamides, wherein the polyacrylamides contain acrylamide, one or more anionic monomers, and excludes a cationic monomer, and a method of using the composition for consumer and/or industrial applications. | 2009-03-12 |
20090069523 | Propylene Random Block Copolymer, Resin Composition Containing the Copolymer and Molded Article Made Thereof - The invention provides a propylene random block copolymer (A) that has a melt flow rate from 0.1 to 100 g/10 min and a melting point from 100 to 155° C. and includes 90 to 60% by weight of a portion insoluble (D | 2009-03-12 |
20090069524 | HYDROSILYLATION PROCESS IN THE PRESENCE OF RUTHENIUM CATALYZERS - Hydrosilylatable compositions employ ruthenium compounds with a ligand sphere comprising at least two independent carbon π-bonded ligands, at least one of these ligands being selected from the group consisting of η | 2009-03-12 |
20090069525 | ORGANOSILICON POLYMERS - The present invention is directed to compositions and processes that are useful in making organosilicon polymers, including cross-linked organosilicon networks. The invention is also directed to articles that incorporate the cross-linked organosilicon networks. | 2009-03-12 |
20090069526 | THERMOPLASTIC POLYURETHANES - A process for the preparation of thermoplastic polyurethane by reacting (a) isocyanates with (b) compounds reactive toward isocyanates and having a molecular weight (M | 2009-03-12 |
20090069527 | AIR DRYING POLYMER - Disclosed is a novel air drying polymer, such as an alkyd, built up from alternating air drying units and spacer units and having a general structure of R | 2009-03-12 |
20090069528 | OPTICALLY-DRIVEN ACTUATOR, METHOD OF MANUFACTURING OPTICALLY-DRIVEN ACTUATOR, CONDENSATION POLYMER AND FILM - An optically-driven actuator includes a condensation polymer containing, on its backbone chain, a photoisomerizable group that undergoes structural change under optical stimulation and deforming depending on the structural change of the photoisomerizable group. The condensation polymer deforms under optical stimulation and is functional as an actuator. | 2009-03-12 |
20090069529 | Titanium oxide sol and process for producing polyalkylene terephthalate therewith - An object of the present invention is to provide an environmentally friendly polymerization catalyst of polyalkylene terephthalate which does not use a heavy metal such as antimony. Another object of the present invention is to provide the method of producing polyalkylene terephthalate using the catalyst. | 2009-03-12 |
20090069530 | POLYESTER FOR TONER - A polyester for a toner, obtainable by polycondensing an alcohol component and a carboxylic acid component containing a (meth)acrylic acid-modified rosin; and a toner containing the polyester for a toner. The polyester for a toner of the present invention is usable as a resin binder for a toner usable in, for example, developing electrostatic latent images formed in electrophotography, electrostatic recording method, electrostatic printing method or the like. | 2009-03-12 |
20090069531 | Polyimide Film - A polyimide film which, when used in FPC production, is reduced in dimensional change during the production steps. In particular, a metal-clad laminate apt to have abnormal parts such as rumples is produced from the film, and an FPC reduced in dimensional change is obtained in high yield. The polyimide film has a tan δ peak temperature within a range of 320° C. or more and lower than 380° C. in measuring a dynamic viscoelasticity, and is characterized by having a maximum sag of 13 mm or less. | 2009-03-12 |
20090069532 | Polyimide Film - Disclosed herein is a polyimide film having an elongation from 50 to 150%, a tensile elastic modulus from 4 to 8 GPa, a tensile strength from 150 to 500 MPa, and a hygroscopicity of 5% or less. The polyimide film has high elastic modulus and tensile strength and an excellent elongation, and thus the polyimide film exhibits excellent material properties when it is used as a base film for TAB and COF, and its properties can be usefully modified using an additive to improve productivity and processibility thereof. | 2009-03-12 |
20090069533 | Benzoxazine monomers, polymers and compositions - Benzoxazine monomers comprising at least one pendant group are described. (Co)Polymers comprising at least one benzoxazine monomer having at least one pendant group are also described. In a preferred embodiment, the pendant group is located in a side chain of the benzoxazine monomer or polymer. Methods for preparing the benzoxazine monomers and polymers are described. Compositions comprising the benzoxazine monomers and polymers have numerous uses including optical materials, and in electronic materials as electrically insulating materials, and as fireproof materials. | 2009-03-12 |
20090069534 | Hydrochloride salts of a glycopeptide phosphonate derivative - Disclosed are hydrochloride salts of telavancin having a chloride ion content of from about 2.4 wt. % to about 4.8 wt. %. The disclosed salts have improved stability during storage at ambient temperatures compared to other hydrochloride salts. Also disclosed are processes for preparing such salts. | 2009-03-12 |
20090069535 | Ligand (ACT-4-L) to a Receptor on the Surface of Activated CD4+ T-Cells - The invention provides ligands and fragments thereof to a receptor on the surface of activated CD4 | 2009-03-12 |
20090069536 | Amide Forming Chemical Ligation - An amide is formed by reacting an α-ketoacid or salt thereof in a decarboxylative condensation reaction with an amine or salt thereof comprising a nitrogen covalently bound to an atom selected from oxygen, nitrogen, and sulfur. The amide bond is formed between the α-carbon of the ketoacid and the nitrogen of the amine. The α-ketoacid can be formed using a novel sulfur reagent. | 2009-03-12 |
20090069537 | Treatment Of Disease By Inducing Cell Apoptosis - The present invention relates generally to the treatment and prevention of diseases characterized by excess cell proliferation and/or activation. In particular, the present invention provides compositions and methods to suppress the activation and/or proliferation of various cells. In preferred embodiments, the present invention provides compositions and methods to suppress the activation and/or proliferation of mesenchymally derived cells (including, but not limited to hepatic stellate cells), as well as cells with abnormal growth characteristics. In particularly preferred embodiments, the present invention provides compositions and methods to inhibit or eliminate fibrosis. In alternative preferred embodiments, the present invention provides compositions and methods to induce fibrosis. | 2009-03-12 |
20090069538 | Method of Producing Peptide - The present invention is related to a method of producing a peptide, characterized in contacting a reaction mixture with a base after a condensation reaction to hydrolyze while a basic condition is maintained until a ratio of a remaining unreacted active ester of an acid component is decreased to 1% or less in a liquid phase peptide synthesis method. According to the invention, a target peptide of high purity can be simply and efficiently produced by a continuous liquid phase synthesis method. Further, the present invention is related to a method of producing a peptide, characterized in using an amide-type solvent immiscible with water in a liquid phase peptide synthesis method. According to the invention, various peptides can be produced by the liquid phase synthesis method without being restricted by the amino acid sequence of the target peptide. | 2009-03-12 |
20090069539 | Androgen regulated prostate specific nucleic acids - The present invention provides novel androgen regulated nucleic acid molecules. Related polypeptides and diagnostic methods also are provided. | 2009-03-12 |
20090069540 | STRETCHABLE COLLAGEN MATERIAL AND MANUFACTURING METHOD AND USE THEREOF - The present invention provides a stretchable collagen material, particularly collagen derived from fishes, having excellent stretching property and mechanical strength, which can be widely used as a cell carrier and medical material, and to a method for manufacturing the same. By thermally treating a gel comprising collagen fiber cross-linked by using cross-linking agent, the collagen enhanced in both stretching property and mechanical strength can be produced. The stretchable collagen material is extremely useful as a cell carrier material and medical material. | 2009-03-12 |
20090069541 | PRODUCTION OF BIOPOLYMER FILM, FIBRE, FOAM AND ADHESIVE MATERIALS FROM SOLUBLE S-SULFONATED KERATIN DERIVATIVES - Film, fibre, foam and adhesive materials are produced from soluble S-sulfonated keratins. Once formed, the films, fibres, foams or adhesives are treated to modify the properties of the materials, in particular to improve the wet strength of the materials. Treatments used include removal of the S-sulfonate group by treatment with a reducing agent, treatment with an acid or treatment with a common protein crosslinking agent or treatment with a reduced form of keratin or keratin protein. The films are made by solvent casting a solution of S-sulfonated keratin proteins, the foam made by freeze-drying a solution of S-sulfonated keratin proteins and the fibres made by extruding a solution of a S-sulfonated keratin protein. | 2009-03-12 |
20090069542 | Process Of Extracting High Quality Proteins From Cereal Grains And Their ByProducts Using Acidic Medium And A Reducing Agent - The present invention is directed to a method for processing a plant-based protein source, the method comprising an acidic extracting solution comprising a reducing agent is useful for extracting and isolating proteins from plant-based protein sources. | 2009-03-12 |
20090069543 | Factor IXa for the treatment of bleeding disorders - The invention provides a method of treating bleeding disorders in a subject by administration of a preparation enriched for Factor IXa. The Factor IXa can be produced by proteolytically activating recombinantly-produced Factor IX. The invention also provides an improved method for producing Factor IXa from a plasma fraction, which method results in a Factor IXa product containing little or no prekallikrein activity, thus reducing the incidence of undesired side effects in a subject. | 2009-03-12 |
20090069544 | HUMANIZED ANTIBODIES THAT RECOGNIZE BETA AMYLOID PEPTIDE - The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of Aβ in the brain of a patient. Preferred agents include humanized antibodies. | 2009-03-12 |
20090069545 | Defensin- specific antibodies - The present invention provides nucleic acid molecules derived from | 2009-03-12 |
20090069546 | PYRAZOLE-BASED CYANINE DYE - Problem Provided is a novel cyanine dye derivative with a pyrazole skeleton and an indole skeleton, having high sensitivity performance in a shorter wavelength region as compared with a conventional optical system, and showing high water solubility.
| 2009-03-12 |
20090069547 | STABILIZATION OF MAMMALIAN MEMBRANE PROTEINS BY SHORT SURFACTANT PEPTIDES - The present invention provides for a method and kits for stabilizing mammalian membrane protein using short surfactant peptides. The mammalian membrane protein can be a G protein-coupled receptor. | 2009-03-12 |
20090069548 | Immobilized Proteins and Methods and Uses Thereof - The invention relates to the field of covalently attaching proteins to a substrate, particularly to methods of immobilizing proteins by posttranslationally modifying a cysteine residue of said protein through the addition of functional groups. The invention also relates to biological molecules used in such techniques, including proteins, and detection methods and kits that utilize such immobilized proteins, such as a microdevice or “protein chip”, a high-throughput screening device, and for the microscopy of proteins on a surface. | 2009-03-12 |
20090069549 | Protein Extraction buffer, a kit comprising it and method of its use - Disclosed are detergent-free protein extract buffers to extract proteins from formalin-fixed paraffin-embedded tissue sections, kit comprising the buffer, and methods for using the buffer to extract proteins from formalin-fixed, paraffin-embedded tissue sections. | 2009-03-12 |
20090069550 | LIGNIN AND OTHER PRODUCTS ISOLATED FROM PLANT MATERIAL, METHODS FOR ISOLATION AND USE, AND COMPOSITIONS CONTAINING LIGNIN AND OTHER PLANT-DERIVED PRODUCTS - Lignin polymers having distinctive properties, including a generally high molecular weight and generally homogeneous size distribution, as well as preservation of native reactive side groups, are isolated by solvent extraction of plant materials. Methods for isolation of lignin polymers, and for use of the isolated lignin polymers are disclosed. Compositions containing lignin isolated from plant materials, such as carbon fiber composites, resins, adhesive binders and coatings, polyurethane-based foams, rubbers and elastomers, plastics, films, paints, nutritional supplements, food and beverage additives are disclosed. Xylose and xylose derivatives, furfural, fermentable sugars, cellulose and hemi-cellulose products may be used directly or further processed. The lignin polymers and other plant-derived products disclosed herein may be produced in abundance at low cost, and may be used as substitutes for feedstocks originating from fossil fuel or petrochemical sources in the manufacture of various products. | 2009-03-12 |
20090069551 | Flavorant Compounds - A compound of the Formula (I) wherein A is selected from the group consisting of —CH═CH—CO—CH3 and —CH2CH2—CO—CH3. The compounds are useful as flavorants in compositions such as foodstuffs, beverages, confectionery, medicinal preparations, dentifrices and mouthwashes. | 2009-03-12 |
20090069552 | Nucleic acids and proteins of insect Or83b odorant receptor genes and uses thereof - The present invention relates to insect odorant receptor genes and methods for identifying odorant receptor genes. The invention provides nucleotide sequences of insect odorant receptor genes Or83b, amino acid sequences of their encoded proteins (including peptides or polypeptides), and related products and methods. The nucleic acids of the invention may be operatively linked to promoter sequences and transformed into host cells. Methods of production of an Or83b odorant receptor protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Antibodies to an Or83b odorant receptor protein, and derivatives and analogs thereof, are provided. Methods for identifying molecules that bind or modulate the activity of these Or83b odorant receptor genes, are provided. Molecules found to bind or modulate the activity of Or83b genes may be formulated into pest control agents by providing a carrier. In a preferred embodiment, molecules that bind or modulate the activity of an Or83b gene from one species but not others is desired. Methods to modify the insect behavior by modifying an insect Or83b odorant are also provided. | 2009-03-12 |
20090069553 | GAMMA-1 AND GAMMA-3 ANTI-HUMAN CD23 MONOCLONAL ANTIBODIES AND USE THEREOF AS THERAPEUTICS - Monoclonal antibodies which specifically bind human CD23, the low affinity receptor for IgE (FceRII/CD23), and contain either a human gamma-1 or human gamma-3 constant domain, are disclosed. The antibodies are useful for modulating or inhibiting induced IgE expression. Accordingly, they have practical utility in the treatment or prophylaxis of disease conditions wherein inhibition of induced IgE production is therapeutically desirable, including allergic conditions, autoimmune diseases and inflammatory diseases. | 2009-03-12 |
20090069554 | METHOD FOR ISOLATING NUCLEIC ACIDS COMPRISING THE USE OF ETHYLENE GLYCOL MULTIMERS - The present invention provides a method of isolating nucleic acid from a sample, said method comprising contacting said sample with a solid support, preferably magnetic beads, in the presence of an ethylene glycol multimer consisting of from 2 to 70 ethylene oxide monomers, preferably tetraethylene glycol, whereby soluble nucleic acid in said sample is bound to the surface of the support, and separating said support with bound nucleic acid from the sample. Kits for performance of the invention are also provided. | 2009-03-12 |
20090069555 | DEVICE AND PROCEDURE FOR AUTOMATED ISOLATION AND PURIFICATION OF NUCLEIC ACIDS FROM COMPLEX STARTING MATERIALS OF THE USERS CHOICE - A reaction unit containing a bottom part and a top part for pipetting a liquid, wherein the bottom part contains a reaction cavity with a permeable filter grid insert and the top part contains a reaction cavity which can be fixed on said bottom part and contains a cavity or covering for receiving a magnet. | 2009-03-12 |
20090069556 | METABOLICALLY STABLE PUROMYCIN ANALOGS - Disclosed are structurally modified, metabolically stable nucleosides having antitumor activity wherein the formation of toxic metabolites is blocked and antimicrobial activity. The disclosure further relates to pharmaceutical compositions comprising one or more disclosed modified nucleosides and to methods of use thereof. | 2009-03-12 |
20090069557 | PREPARATION OF GEMCITABINE - A process for preparation of gemcitabine hydrochloride and purification thereof. | 2009-03-12 |
20090069558 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS - A method of making chlorins comprises the steps of reacting (e.g. condensing) a dipyrrin western half intermediate with an eastern half intermediate to form a tetrahydrobilene, and then cyclizing the tetrahydrobilene to form a chlorin. Intermediates including tetrahydrobilenes useful in such reactions are also described. | 2009-03-12 |
20090069559 | Compositions and methods for modulating sirtuin activity - The present invention is based, in part, on our discovery of compounds that inhibit an activity of a sirtuin (e.g., compounds that inhibit or preferentially inhibit an activity of SIRT2) and are therefore believed useful in the treatment or prevention of diseases associated with sirtuin activity. These diseases include, but are not limited to, neurological disorders such as Parkinson's Disease (PD). | 2009-03-12 |
20090069560 | Process For Obtaining Levofloxacin Free From Salts - This invention relates to a process for obtaining levofloxacin free from salts. In this process the starting product used is the compound (V), alkaline hydrolysis of which within a water-(C | 2009-03-12 |
20090069561 | CLICK CHEMISTRY ROUTE TO TRIAZOLE DENDRIMERS - The high efficiency and fidelity of click chemistry permits a large number of diverse dendrimers encompassing a wide variety of functionalities at the chain ends, repeat units, and/or core to be prepared. Almost quantitative yields were obtained during the synthesis. In some cases, filtration or solvent extraction was the only method required for purification. These features represent a significant advancement in dendrimer chemistry and demonstrate an evolving synergy between organic chemistry and functional materials. | 2009-03-12 |
20090069562 | Process for the preparation of alfuzosin - An improved process for the preparation of N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydrofuran-2-carboxamide of Formula (I), | 2009-03-12 |
20090069563 | Rosuvastatin intermediates and their preparation - Provided are processes and intermediates for preparation of rosuvastatin. | 2009-03-12 |
20090069564 | Methods and Compositions for Selectin Inhibition - The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian adhesion proteins known as selectins. In some embodiments, methods for treating selectin mediated disorders are provided which include administration of compound of Formula I: | 2009-03-12 |
20090069565 | NEW INDOLE DERIVATIVES AS FACTOR XA INHIBITORS - The present invention relates to compounds of formula I, | 2009-03-12 |
20090069566 | LEAD-FREE PRIMARY EXPLOSIVE COMPOSITION AND METHOD OF PREPARATION - Embodiments of the present subject matter provide a compound and material that may be used as a lead-free primary explosive. An embodiment of the present subject matter provides the compound copper(I) nitrotetrazolate. Certain embodiments of the present subject matter provide methods for preparing lead-free primary explosives. The method includes: providing cuprous salt; providing water; providing 5-nitrotetrazolate salt; combining the cuprous salt, water and 5-nitrotetrazolate salt to form a mixture; and heating the mixture. The method may also include providing cuprous chloride and providing sodium 5-nitrotetrazolate. Certain embodiments of the present subject matter also provide methods for preparing copper(I) nitrotetrazolate. The method includes: providing cuprous salt; providing water; providing 5-nitrotetrazolate salt; combining the cuprous salt, water and 5-nitrotetrazolate salt to form a mixture; and heating the mixture. The method may also include providing cuprous chloride and providing sodium 5-nitrotetrazolate. | 2009-03-12 |
20090069567 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS - Hafnium complexes of heterocyclic organic ligands having improved solubility in aliphatic hydrocarbon solvents and their use as components of olefin polymerization catalysts as well as novel syntheses of component parts thereof are disclosed. | 2009-03-12 |
20090069568 | METHOD FOR PRODUCING INDAZOL-3-YLMETHYL PHOSPHONIUM SALT - The present invention provides a method for producing an indazol-3-ylmethyl phosphonium salt represented by Formula (IV): | 2009-03-12 |
20090069569 | CYCLOADDITION OF AZIDES AND ALKYNES - This invention provides a process which comprises contacting, in a reaction zone, at least one organic azide, at least one alkyne, and at least one N-heterocyclic carbene copper compound in which the ligands are either (i) a halide and an N-heterocyclic carbene or (ii) two N-heterocyclic carbenes and a BF | 2009-03-12 |
20090069570 | Novel Process for Producing Ramosetron or Its Salt - [Problems] To provide a novel process for producing ramosetron or its salt that is useful as a pharmaceutical, especially as a therapeutic and/or preventive agent for digestive symptoms caused by administration of an anti-malignant tumor agent, diarrheal-type irritable bowel syndrome, diarrheal symptoms of irritable bowel syndrome, etc.
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20090069571 | Process for the Preparation of 5-Alkylthioalkylamino-I-Phenyl-Pyrazoles - The invention relates to a process for the preparation of 5-alkylthioethylamino-1-phenyl-pyrazoles of formula (I) and the preparation of 5-methylamino-1-phenylpyrazole intermediates. | 2009-03-12 |
20090069572 | PROCESS FOR THE PREPARATION OF PYRAZOLES - The present invention relates to a process for the preparation of compounds of formula I | 2009-03-12 |
20090069573 | Method for the purification of betaines - The invention relates to a method for purification of synthetically-produced compounds, comprising a betaine structure in the molecule, for example, indocyan green, characterized in that reaction by-products, starting materials and/or other impurities such as NaI used during production are separated by extraction. | 2009-03-12 |
20090069574 | Process for the synthesis of an ace inhibitor - A process for the synthesis of trandolapril which comprises condensing N-[I-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride with trans octahydro-1H-indole-2-carboxylic acid in a first organic solvent comprising a water immiscible inert organic solvent and in the presence of a base, and isolating trandolapril from a second organic solvent. N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride may also be condensed with (2S,3aR,7aS) octahydro-1H-indole-2-carboxylic acid in a first organic solvent and in the presence of a base, and trandolapril isolated. There is also provided a process for the resolution of racemic trans octahydro-1H-indole-2-carboxylc acid. | 2009-03-12 |
20090069575 | Process For The Preparation Of (S)-Alpha-Ethyl-2-Oxo-1-Pyrrolidineacetamide And (R)-Alpha-Ethyl-2-Oxo-Pyrrolidineacetamide - A process provided for the preparation of the (S)— and (R)-alpha-ethyl-2-oxo-1-pyrrolidineacetamide of formula:(1) from (RS)-alpha-ethyl-2-oxo-1-pyrrolidineacetic acid of formula:(2) comprising: i) combining the (RS)-2 with a chiral base (resolving agent) in a resolution solvent and crystallizing from the said mixture the diastereomeric salt of (S)— or (R)-2 and chiral base; ii) regenerating (S)— or (R)-2 from the crystallized diastereomeric salt by treating with a suitable acid or acidic ion-exchange resin; iii) optionally regenerating (R)— or (S)-2 or their mixture (predominantly one enantiomer) from the crystallization mother liquor by treating with a suitable acid or acidic ion-exchange resin; iv) optionally epimerizing (RS)-2 by treating (R)— or (S)-2 or their mixture (predominantly one enantiomer) of step iii with an acid anhydride; V) optionally converting (RS)-2 of step iv into enantiomerically enriched (S)— or (R)-2 through steps i and ii; vi) formation of the mixed anhydride by reacting (R)— or (S)-2 with an alkyl or aryl sulfonyl halogen compound RSO2X in the presence of a suitable base; and vii) reacting the mixed anhydride with ammonia; wherein R represents C 1 to C 15 alkyl or aryl groups such as methyl, ethyl, p-toluenyl, 2,4,6-trimethylbenzyl, 2,4,6-trichloribenzyl, and X represents a halogen atom such as F, Cl and Br atoms. | 2009-03-12 |
20090069576 | PROCESS FOR PRODUCTION OF 1-(3-(2-(1-BENZOTHIOPHEN-5-YL)-ETHOXY)PROPYL)AZETIDIN-3-OL OR SALTS THEREOF - A Process for production of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or salts thereof which comprises using as a starting compound as a (phenylthio)acetic acid derivative or salts thereof represented by the general formula: | 2009-03-12 |
20090069577 | Silicon-Based Cross-Coupling Reagent and Production Method of Organic Compound Using the Same - In one embodiment of the present invention, a silicon-based cross-coupling reagent is disclosed which is a highly stable tetraorganosilicon compound allowing for a cross-coupling reaction under mild reaction conditions without using fluoride ions, transition metal promoter, or strong bases, and the residue of the silicon reagent can be recovered and reused. The silicon-based cross-coupling reagent is a silicon compound in which an o-hydroxymethylphenyl group is connected to a silicon atom for intramolecular activation. | 2009-03-12 |
20090069578 | Novel asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid - The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin. | 2009-03-12 |
20090069579 | PROCESS AND COMPOUND - A process for preparing intermediate compounds useful in the preparation of statins. The process is particularly useful for the preparation of atorvastatin. The process involves the reduction of two ketone groups at the same time using either a chiral transition metal catalyst or an enzyme based system. | 2009-03-12 |
20090069580 | Alkene Hydrofunctionalization Reactions - A reductive cross coupling reaction process for functionalization of a nucleophilic alkene can be achieved. The nucleophilic alkene and a nucleophilic cross coupling partner compound can be reacted in the presence of an oxidizable alcohol and a suitable catalyst to form a reductive coupling product. Various additives can also be useful to refine the process such as by mitigating certain undesirable intermediates, facilitating specific site selectivity for various substitutions or reaction sites, etc. Chiral additives can be optionally used which act to provide asymmetric catalysis, e.g. allow for regioselective and stereoselective production of reductive coupling products. A reductive cross coupling pathway can include oxidizing the oxidizable alcohol to form a catalyst hydride. The nucleophilic alkene can be inserted into the catalyst hydride to form a catalyst-alkyl intermediate. Further, the catalyst-alkyl intermediate can be transmetallized with the nucleophilic cross coupling partner compound to form a transmetallated intermediate. The catalyst can be reductively eliminated to form the reductive coupling product and a reduced catalyst. Finally, the reduced catalyst can be oxidized under aerobic conditions, for example with oxygen, to form the oxidized catalyst and subsequent repetition through the cyclic pathway. | 2009-03-12 |
20090069581 | PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES - The present invention provides processes and intermediates for the synthesis of ramelteon. | 2009-03-12 |
20090069582 | METHOD FOR MANUFACTURE OF ESCITALOPRAM - This patent discloses a method for resolution of 4-[4-(dimethylamino)-1-(4′-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile as a racemic or non-racemic enantiomer mixture into its isolated enantiomers, said method comprising the step of fractionally crystallizing 4-[4-(dimethylamino)-1-(4′-fluoro-phenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile as a salt with the (+)—(S,S)— or (−)—(R,R)-enantiomer of O,O′-di-p-toluoyl-tartaric acid in a solvent system comprising 1-propanol, ethanol or acetonitrile. | 2009-03-12 |
20090069583 | ETHYLENE OXIDE PRODUCTION USING FIXED MODERATOR CONCENTRATION - A method for controlling ethylene oxidation uses ethylene and oxygen, in conjunction with a silver based catalyst, a moderator and a co-moderator, to form ethylene oxide. When controlling the ethylene oxidation reaction, the moderator concentration is maintained constant within a comparatively narrow operative concentration range and the co-moderator concentration is varied within a comparatively wider operative concentration range, to optimize a catalyst property such as the catalyst activity and/or the catalyst selectivity. | 2009-03-12 |
20090069584 | Levonorgestrel Crystallization - The present invention provides for a crystalline polymorph of levonorgestrel and processes for making the same. | 2009-03-12 |
20090069585 | Transesterification Reacton of Triglycerides and Monohydric Alcohols - A process for producing monoesters and glycerol from triglycerides and monohydric alcohols by transesterification in the presence of phase-transfer catalysts and base initiators, produced in a batch or continuous mode. Reaction mixtures comprising triglycerides such as vegetable triglycerides, monohydric alcohols such as methanol or ethanol, base initiators such as alkali metal hydroxides or carbonates and phase-transfer catalysts such as quaternary ammonium or quaternary phosphonium salts for performing transesterification reactions. The reaction product comprises a mixture of monoesters and glycerol. The monoesters produced are useful as fuels, cleaning solvents and other industrial applications. For example, fatty acid methyl esters are produced by the transesterification reaction between fatty vegetable triglycerides and methanol in the presence of catalytic quantities of both methyl tricaprylyl ammonium chloride and sodium hydroxide at a temperature of about 70° C. | 2009-03-12 |
20090069586 | METHOD FOR PRODUCING FATTY ACID ALKYL ESTERS AND/OR GLYCERIN - To provide: a production method using a catalyst which can substantially suppress leaching of active metal components and exhibit high activity for both reactions of transesterification of glycerides and esterification of free fatty acids each contained in a fat or oil; and the catalyst. A method for producing fatty acid alkyl esters and/or glycerin comprising a step of bringing a fat or oil into contact with an alcohol in the presence of a catalyst, wherein the catalyst is at least one catalyst selected from the group consisting of the following (I) to (V):
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20090069587 | Enzymatic Degumming Utilizing a Mixture of PLA and PLC Phospholipases with Reduced Reaction Time - A method for degumming an oil composition comprises the steps of (a) providing an oil composition containing a quantity of phospholipids, (b) contacting said oil composition simultaneously with one or more phospholipase A enzymes and one or more phospholipase C enzymes, under conditions sufficient for the enzymes to react with the phospholipids to create phospholipid reaction products, and (c) separating the phospholipids reaction products from the oil composition, the remaining oil composition after the separation being a degummed oil composition, whereby during step (b) the reaction of said one or more phospholipase A enzymes proceeds at a faster rate than it would in the absence of said one or more phospholipase C enzymes, and wherein the reaction of step (b) continues for a duration of less than about one hour. | 2009-03-12 |
20090069588 | Precursors for CVD Silicon Carbo-nitride Films - Classes of liquid aminosilanes have been found which allow for the production of silicon-containing films. These aminosilanes, in contrast, to some of the precursors employed heretofore, are liquid at room temperature and pressure allowing for convenient handling. In addition, the invention relates to a process for producing such films. | 2009-03-12 |
20090069589 | PROCESSES FOR PRODUCING HYDROHALOCARBON AND HALOCARBON COMPOUNDS USING SILICON TETRAFLUORIDE - Methods and systems for producing hydrohalocarbon and/or halocarbon compounds with an inorganic fluoride (e.g., silicon tetrafluoride (SiF | 2009-03-12 |
20090069590 | PROCESS FOR PREPARING AMINOALKYLNITRILES AND DIAMINES FROM SUCH NITRILES - The present invention relates to a process for preparing an aminoalkyl nitrile by reaction of a corresponding monoamine with a corresponding alkenyl nitrile in a continuous mode of operation, which comprises the steps
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20090069591 | Calcium Bis [ (2S) -3- [3-[ (2S) -3- (4-Chloro-2-Cyanophenoxy) -2- Fluoropropoxy]Phenyl] -2- Isopropoxypropionate] and Intermediate Thereof - The present invention relates to calcium bis[(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate] represented by formula (I), a hydrate thereof, a crystal of the compound of formula (I), and a crystal of the hydrate of the compound of formula (I) which are useful as pharmaceuticals, and to processes for producing the same, and intermediates therefore, and processes for production thereof. | 2009-03-12 |
20090069592 | METHOD FOR SYNTHESIZING RADIOACTIVE LIGAND HAVING 18F-LABELED FLUOROBENZENE RING - A phenyl tin compound is synthesized by using a derivative having various functional groups and a bromo- or iodo-benzene ring as a labeling material of a radioactive ligand. On the other hand, a novel hydroxytosyl iodobenzene compound having an electron-donating group is obtained by oxidizing iodobenzene having one or more electron-donating groups and reacting it with tosylic acid. Then, a diphenyliodonium salt which is a labeling precursor is synthesized by reacting the resulting compound with various phenyl tin compounds. Finally, a | 2009-03-12 |
20090069593 | Novel asymmetric synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid - The invention encompasses processes for the synthesis of (S)-(+)-3-(aminomethyl)-5-methylhexanoic acid, (S)-Pregabalin, and intermediates of (S)-Pregabalin. | 2009-03-12 |