11th week of 2010 patent applcation highlights part 53 |
Patent application number | Title | Published |
20100069611 | CYTOLETHAL DISTENDING TOXINS AND DETECTION OF CAMPYLOBACTER BACTERIA USING THE SAME AS A TARGET - The present inventors succeeded in cloning the CDT genes of | 2010-03-18 |
20100069612 | WATER-SOLUBLE KERATIN DERIVATIVE AND USE THEREOF - The present invention provides a novel water-soluble keratin derivative and applications thereof. Water-soluble keratin produced by the alkali treatment of feathers, and modified keratin, gives the following useful materials: (1) a high energy wave absorber, (2) a luminescent substrate, (3) a material weatherproofness improver, (4) a water repellant, and (5) a foaming agent. | 2010-03-18 |
20100069613 | IMPLANTABLE MATERIALS AND COMPOSITIONS - A method of concentrating proteins from whole blood comprising exposing whole blood to a covalently crosslinked hydrogel to remove water from the blood into the hydrogel to thereby concentrate the proteins in the whole blood. The hydrogel may absorb, for example, 50% or 90% of the water from the blood while excluding proteins with a weight of more than about 15,000 Daltons. In some embodiments, the hydrogels are dry, sterile, and spherical. | 2010-03-18 |
20100069614 | Antibody producing non-human mammals - Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal. | 2010-03-18 |
20100069615 | Regulation of Human Transmembrane Serine Protease - Reagents that regulate human transmembrane serine protease activity and reagents that bind to human transmembrane serine protease gene products can be used to regulate extracellular matrix degradation. Such regulation is particularly useful for treating COPD, metastasis of malignant cells, tumor angiogenesis, inflammation, atherosclerosis, neurodegenerative diseases, and pathogenic infections. | 2010-03-18 |
20100069616 | ENGINEERED ANTIBODY-NANOPARTICLE CONJUGATES - Conjugates of a C-terminal modified diabody and a nanoparticle are provided in which the C-terminal modification introduces a cysteine residue at a C-terminus of the diabody and the diabody is covalently linked to the nanoparticle via a heterobiofunctional linker attached to the introduced cysteine residue. | 2010-03-18 |
20100069617 | ENHANCED PROTEIN AGGREGATE REMOVAL BY MIXED MODE CHROMATOGRAPHY ON HYDROPHOBIC INTERACTION MEDIA IN THE PRESENCE OF PROTEIN-EXCLUDED ZWITTERIONS - This invention relates to methods for enhancing purification of proteins such as monoclonal antibodies by chromatography on carboxyl group-containing HIC supports in the presence of zwitterions that are excluded from protein surfaces. In certain embodiments, the invention may permit more effective separation of non-aggregated protein from aggregated protein. | 2010-03-18 |
20100069618 | PROCESS FOR PREPARING MATERIALS BY GRAFTING HALOGENATED PHOSPHORUS-CONTAINING GROUPS ONTO AN INORGANIC SURFACE - The invention concerns a process for preparing a hybrid organic-inorganic material (HOIM) with phosphorus-containing bridges between the surface of an inorganic substrate containing an element M and one or more organic groups of the covalent M-O-P-R type, said process using, as a precursor for said organic group or groups, at least one organophosphorus acid halide with formula R | 2010-03-18 |
20100069619 | STILBENE DERIVATIVES FOR ADP-RIBOSYL CYCLASE INHIBITORS - The present disclosure relates to bisphenyl compounds that are useful for inhibit the ADP-ribosyl cyclase (ADPR-cyclase). More particularly, the disclosed compounds can be used for treatment and prevention of hypertension, hypertensive cardiac hypertrophy, diabetes, and diabetic nephropathy, in which pathogenesis ADPR-cyclase is involved. The compounds and compositions of the invention can be used for treatment and prevention of cardiovascular disease and related disease states, particularly, hypertension or diabetes related disorders, such as, hypertensive cardiac hypertrophy, diabetic nephropathy, and the like. | 2010-03-18 |
20100069620 | NOVEL COMPOSITIONS OF CHEMICALLY MODIFIED SMALL INTERFERING RNA - The present invention is directed to compositions comprising chemically modified siRNA that have high specificity by virtue of no or insignificant off-target activity of the sense strand, no or insignificant induction of IFN-like responses, high potency to offset oligonucleotide manufacturing costs, favorable manufacturing chemistry, and effective means of intracellular delivery both in vitro, during target validation and model studies, and in vivo, during animal model studies and clinical trials in humans. | 2010-03-18 |
20100069621 | POLYNUCLEOTIDES AND RELATED NANOASSEMBLIES, STRUCTURES, ARRANGEMENTS, METHODS AND SYSTEMS - A linker polynucleotide for attaching a nanomaterial to a polynucleotidic platform and related nanoassemblies, arrangements, structures, methods and systems. | 2010-03-18 |
20100069622 | siRNA targeting amyloid beta (A4) precursor protein (APP) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for APP. | 2010-03-18 |
20100069623 | Method for preparing oligonucleotides - A solution phase synthesis method for preparing an oligonucleotide, wherein at least some of the reagents are solid supported. The method suitable for large-scale synthesis comprises coupling a protected compound with a nucleotide derivative having a protection group in the presence of a solid supported activator to give an elongated oligonucleotide with a P(III)-internucleotide bond; optionally processing the elongated oligonucleotide by capping by reaction with a solid supported capping agent and/or by oxidizing or sulfurizing by reaction of the oligonucleotide with a solid supported oxidizing or sulfurization reagent; and removing the protection group. The coupling may include reacting a 3′-protected compound of formula: | 2010-03-18 |
20100069624 | Nucleic Acid Mediated Electron Transfer - The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties are covalently bound to the ribose-phosphate backbone of a nucleic acid at predetermined positions. The resulting complexes represent a series of new derivatives that are bimolecular templates capable of transferring electrons over very large distances at extremely fast rates. These complexes possess unique structural features which enable the use of an entirely new class of bioconductors and photoactive probes. | 2010-03-18 |
20100069625 | PROCESS FOR PREPARING OF 2'-DEOXY-2'2'-DIFLUOROCYTIDINE - Disclosed is a method for preparing 2′-deoxy-2′,2′-difluorocytidine of Formula I comprising, preparing an optically pure 3R-hydroxypropane amide compound of Formula VIII from an optical ester compound of Formula IX using an optically active chiral amine, preparing an optically pure D-erythro-2,2-difluoro-2-deoxy-1-oxoribose compound of Formula V from the compound of Formula VIII, glycosylating the compound of Formula V with a nucleobase to prepare the 2′-deoxy-2′,2′-difluorocytidine of Formula I as a β-nucleoside. With the present invention, it is possible to prepare an optically pure compound of Formula I in a high purity and a high yield. In the Formulae, R | 2010-03-18 |
20100069626 | NANO-CATALYTIC-SOLVO-THERMAL TECHNOLOGY PLATFORM BIO-REFINERIES - Methods of making glucose and/or furfural from biomass require one or more supercritical fluids that may be used to process biomass, cellulose from the biomass, and/or xylose from the biomass. Examples of supercritical fluids for use in processing biomass include ethanol, water, and carbon dioxide at a temperature and pressure above the critical points for ethanol and carbon dioxide but at a temperature and/or pressure below that of the critical point for water. A supercritical fluid containing carbon dioxide and water may be used to convert cellulose to glucose or convert xylose to furfural. The fluid has a temperature and pressure above the critical point of carbon dioxide, but at least one of the temperature and pressure is below the critical point for water. | 2010-03-18 |
20100069627 | NOVEL METHOD FOR THE DIASTEREOSELECTIVE PRODUCTION OF A CHIRAL PRIMARY AMINE ON A STEROID - The invention relates to a diastereoselective method for obtaining a primary amine on a steroid, comprising the reduction of an oxime by lithium in ammonia at a low temperature in an ether/alcohol mixture. | 2010-03-18 |
20100069628 | Multidentate AZA Ligands Able to Complex Metal Ions And The Use Thereof In Diagnostics And Therapy - Compounds of the formula: | 2010-03-18 |
20100069629 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF - A drug is provided that is useful as a preventive or therapeutic for cancer as a result of having superior PI3K inhibitory effects as well as superior stability in the body and water-solubility. | 2010-03-18 |
20100069630 | NAPHTHALENYLOXYPROPENYL DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME - The present invention discloses novel naphthalenyloxypropenyl derivatives useful for inhibiting the enzyme activity of histone deacetylase, leading effective suppression of cancer cell proliferation. | 2010-03-18 |
20100069631 | Integrated Process for Urea and Melamine Production - In an integrated process for urea and melamine production, urea is produced in a urea plant ( | 2010-03-18 |
20100069632 | SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND PROCESS FOR PREPARING THE SAME - The present invention relates to salts of a pyrrolopyrimidinone derivative having superior PDE-5 inhibition activity and a process for preparing the same. More particularly, the present invention relates to a crystalline acid addition salt prepared by reacting a pyrrolopyrimidinone derivative with an acid selected from gentisic acid, maleic acid, citric acid, fumaric acid and tartaric acid. With no hygroscopic property and superior long-term storage stability, photostability and thermal stability, the salts of the pyrrolopyrimidinone derivative are appropriate to be prepared into medications and, with superior PDE-5 inhibition activity, are useful for the treatment and prevention of erectile dysfunction, pulmonary arterial hypertension, chronic obstructive pulmonary disease, benign prostatic hypertrophy and lower urinary tract diseases. | 2010-03-18 |
20100069633 | PALIPERIDONE KETONE - A compound of formula (7.2) or an acid addition salt thereof. | 2010-03-18 |
20100069634 | PYRIMIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE - Disclosed are compounds of the formula I: | 2010-03-18 |
20100069635 | ROSUVASTATIN DEHYDROABIETYLAMINE SALT - There is provided a compound, which is dehydroabietylamine salt of rosuvastatin. Also provided are processes for making rosuvastatin calcium that include formation of dehydroabietylamine salt of rosuvastatin. | 2010-03-18 |
20100069636 | Quinoxaline Derivative, and Organic Semiconductor Device, Electric Field Light Emitting Device, and Electronic Device Which Have the Same - Target is to provide an organic compound material having a bipolar character. | 2010-03-18 |
20100069637 | CRYSTALLINE SALT FORMS OF A 5,6,7,8-TETRAHYDRO-1,2,4-TRIAZOLO[4,3-a]PYRAZINE DERIVATIVE - This invention provides novel crystalline acid salt forms of 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine, i.e. sitagliptin, to processes for their preparation and isolation, and to pharmaceutical compositions comprising the same. | 2010-03-18 |
20100069638 | SULFONAMIDE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONISTIC ACTIVITY - The present invention provides an sulfonamide derivative having DP receptor antagonistic activity and a pharmaceutical composition comprising the said compound as an active ingredient, and further a therapeutic agent for treating allergic diseases. | 2010-03-18 |
20100069639 | Processes for the Synthesis of Five and Six Membered Heterocyclic Rings - The present invention provides processes for the synthesis of five and six membered rings. In particular, the present invention provides processes for the synthesis of five and six membered rings in alkaloids. | 2010-03-18 |
20100069640 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID - A compound represented by the following formula or a salt thereof: | 2010-03-18 |
20100069641 | PROCESS FOR THE PREPARATION OF SODIUM SALT OF 1-(((1(R)-(3-(2-(7-CHLORO-2-QUINOLINYL)-ETHENYL)PHENYL)-3-(2-(1-HYDROXY-1- -METHYLETHYL)PHENYL)PROPYL)SULFANYL)METHYL)CYCLOPROPANEACETIC ACID - A novel process for the preparation of a sodium salt of 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methyl-ethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid, comprising: a) reacting a compound of Formula 1 with methanesulfonyl chloride in the presence of a tertiary amine to yield a crude solution of a compound of Formula 2; b) filtering the crude solution of compound of Formula 2 obtained in a) to remove solid amine hydrochloride, reacting the filtrate without isolation or further purification with a compound of Formula 3, and isolating 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid; c) reacting the 1-(((1(R)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid isolated in b) with tert-butylamine to yield a compound of formula 4; d) isolating and purifying the compound of formula 4; and e) converting the compound of formula 4 to a compound of formula 5. | 2010-03-18 |
20100069642 | CRYSTALLINE S-(-)-AMLODIPINE ADIPIC ACID SALT ANHYDROUS AND PREPARATION METHOD THEREOF - Disclosed are crystalline S-(−)-amlodipine adipic acid salt anhydrous and a preparation method thereof. The crystalline S-(−)-amlodipine adipic acid salt anhydrous exhibits excellent physical and chemical properties including non-hygroscopicity, solubility, thermal stability, and photostability, and is superior in formulation processability and long-term storage safety. | 2010-03-18 |
20100069643 | Convergent Process for the Synthesis of Taxane Derivatives - The application provides a process for the preparation of taxane derivatives and intermediates useful in such processes. | 2010-03-18 |
20100069644 | Method of regio-selective synthesis of tri-substituted-1, 2, 3-triazoles - The embodiments provide for region-selective synthesis of tri-substituted 1,2,3-traizoles. A first embodiment provides for the selective N-2 alkylation of a 4,5-disubstituted 1,2,3-triazole. A second embodiment provides for the selective acetylation of a 4,5-disubstituted 1,2,3-triazole. A third embodiment provides for the selective arylation of a 4,5-disubstituted 1,2,3-triazole. | 2010-03-18 |
20100069645 | 2-(5-BROMO-4-(4-CYCLOPROPYLNAPHTHALEN-1-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACET- IC ACID AND METHYL ESTER - A series of S-triazolyl α-mercaptoacetanilides having general structure (I) are provided, where Q is CO | 2010-03-18 |
20100069646 | Process for preparing difluoromethylpyrazolyl carboxylates - The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylates of the formula I | 2010-03-18 |
20100069647 | Carbazole Derivative, Light-Emitting Element Material, Light-Emitting Element, and Light-Emitting Device - An object is to provide a carbazole derivative which has a wide band gap and with which excellent blue color purity is obtained. In addition, another object is to provide highly reliable light-emitting elements, light-emitting devices, lighting devices, and electronic devices in which the carbazole derivative is used. Carbazole derivatives represented by the general formulas (1), (P1), and (M1) are provided. Further, light-emitting elements, light-emitting devices, and electronic devices which are formed using the carbazole derivative represented any of the general formulas (1), (P1), and (M1) are provided. | 2010-03-18 |
20100069648 | Adamantane-Dipyrromethane Derivatives, Method Of Preparation And Applications In Anion Sensing - Aamantane dipyrromethane derivatives are obtained by reacting adamantane carbonyl derivatives with pyrrole or pyrrole derivative, in the presence of acid. Adamantane-dipyrromethanes are used to bind anions of the group consisting of: F—, Cl—, Br—, acetate, HSO4— NO3—, and H2PO4—, and particularly F—. | 2010-03-18 |
20100069649 | METHOD OF PURIFICATION OF (S)-N-METHYL-3-(1-NAPHTYLOXY)-3-(2-THIENYL) PROPYLAMINE HYDROCHLORIDE (DULOXETINE) - A method of purification of (5)-7V-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride of formula I, comprising (a) transformation of the substance of formula I to its free base by the action of an organic or inorganic base in an aqueous environment; and (b) transformation of the base of the substance of formula I to crystalline hydrochloride by the action of hydrochloric acid or gaseous HCl in an organic solvent or a mixture of organic solvents. A method of purification of (S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride of formula I, comprising dissolution of this substance in a minimum quantity of methanol containing 0 to 50% of water and its transformation back to the solid phase (precipitation) by addition of a less polar solvent. | 2010-03-18 |
20100069650 | POLYNARY METAL OXIDE PHOSPHATE - A novel polynary metal oxide phosphate of the general formula I | 2010-03-18 |
20100069651 | PROCESS FOR PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL - The present invention relates to a process for preparation of a delta-9-tetrahydrocannabinol compound or derivative thereof involving treating a first intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the delta-9-tetrahydrocannabinol compound or derivative thereof. Another aspect of the present invention relates to a process for preparation of a cannabidiol or cannabidiolate compound involving reacting a first starting compound with a second starting compound in the presence of a metal triflate catalyst, under conditions effective to form the cannabidiol or cannabidiolate compound. The present invention also relates to a compound of the formula: | 2010-03-18 |
20100069652 | The Process for Preparing Nebivolol - The present invention relates to a process for the preparation of Nebivolol and, more particularly, to an improved method of synthesizing 6-fluoro chroman epoxides of formula (I) key intermediates in preparing nebivolol. | 2010-03-18 |
20100069653 | METHOD FOR ENANTIOSELECTIVE HYDROGENATION OF CHROMENES - A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained. | 2010-03-18 |
20100069654 | PROCESS FOR THE PREPARATION OF TAUROURSODESOXYCHOLIC ACID - The present invention relates to a novel method for preparing tauroursodeoxycholic acid which comprises a step of selective precipitation of the impurities present in the suspension obtained from the reaction of an aqueous solution of sodium taurinate with an acetonic solution of a mixed anhydride of ursodeoxycholic acid with an alkyl chloroformate. | 2010-03-18 |
20100069655 | NOVEL STRONG BORON-CONTAINING ACIDS, THE PREPARATION AND USE THEREOF - The invention relates to boron-containing acids of the general formula (I) [B(R | 2010-03-18 |
20100069656 | PROCESS FOR PREPARING ISOCYANATOORGANOSILANES - Isocyanate-functional silanes, particularly isocyanate-functional α-silanes, are prepared in good yield by a liquid phase thermolysis conducted in the presence of a catalyst at a pressure of >100 mbar, or >80 mbar when a thin-film evaporator is used. | 2010-03-18 |
20100069657 | METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF - The invention relates to general syntheses of (6H)-dibenz[c,e] [1,2]-oxaphosphorins which are substituted with nitrogen compounds on the phosphorus atom and comprising commercially available 6H-dibenz[c,e] [1,2]-oxaphosphorin-6-oxides. These nitrogen-containing (6H)-dibenz[c,e] [1,2]-oxaphosphorins can be used as reactive starting substances for further syntheses or as flameproofing agents or as stabilisers. | 2010-03-18 |
20100069658 | STABILIZATION OF DIESTERS OF DICARBONIC ACID - By using phosphorus compounds, diesters of dicarbonic acid may be stabilized against thermal and chemical decomposition over a relatively long period. Mixtures of diesters of dicarbonic acid and phosphorus compounds are outstandingly suitable for preserving foods. | 2010-03-18 |
20100069659 | PROCESS FOR PRODUCING GEOMETRIC SHAPED CATALYST BODIES - A process for producing geometric shaped catalyst bodies K whose active material is a multielement oxide of stoichiometry | 2010-03-18 |
20100069660 | PROCESS FOR PRODUCING GEOMETRIC SHAPED CATALYST BODIES - A process for producing geometric shaped catalyst bodies K whose active material is a multielement oxide of stoichiometry | 2010-03-18 |
20100069661 | PROCESS FOR CARBONYLATING PHENYLALKYL DERIVATIVES BY MEANS OF CARBON MONOXIDE - The invention is directed a process of preparing a compound of formula (I), | 2010-03-18 |
20100069662 | INTEGRATED PROCESS AND APPARATUS FOR PREPARING ESTERS OF METHACRYLIC ACID FROM ACETONE AND HYDROCYANIC ACID - The subject-matter of the present invention relates in principle to a process for preparing alkyl esters of methacrylic acid and its conversion products, which can be used in a multitude of chemical synthesis processes which can lead to a wide variety of different further processing products, and to an apparatus for performing this process. | 2010-03-18 |
20100069663 | STEREOSELECTIVE ONE STEP FLUORINATION PROCESS FOR THE PREPARATION OF 2-FLOUROPROPIONATE - The current invention describes a one-step process for the synthesis of 2-fluoropropionates from lactic acid ester derivatives using TFEDMA. | 2010-03-18 |
20100069664 | METHOD FOR PREPARING (E3,Z5)-3,5-ALKADIENYL ACETATE - Provided is a method for preparing (E3,Z5)-3,5-alkadienyl acetate and (E3,Z5)-3,5-dodecadienyl acetate which is a sex pheromone of Brazilian apple leafminer. Specifically, provided is a method for preparing (E3,Z5)-3,5-alkadienyl acetate, comprising steps of hydrolyzing 5,5-diethoxy-(Z3)-3-pentenyl methoxymethyl ether in the presence of an acid to obtain 4-formyl-(E3)-butenyl methoxymethyl ether; reacting the 4-formyl-(E3)-butenyl methoxymethyl ether with alkylidene triphenylphosphorane in accordance with the Wittig reaction to obtain (E3,Z5)-3,5-alkadienyl methoxymethyl ether; and obtaining (E3,Z5)-3,5-alkadienyl acetate using the (E3,Z5)-3,5-alkadienyl methoxymethyl ether as a starting substance. | 2010-03-18 |
20100069665 | PROCESS FOR PRODUCING ISOCYANATES - An object of the present invention is to provide a process allowing long-term, stable production of isocyanates at a high yield without the various problems found in the prior art during production of isocyanates without using phosgene. The present invention discloses a process for producing an isocyanate by subjecting a carbamic acid ester to a decomposition reaction in the presence of a compound having an active proton and a carbonic acid derivative. | 2010-03-18 |
20100069666 | IMPROVED METHOD FOR THE PRODUCTION OF UNSATURATED CARBOXYLIC ACID ANHYDRIDES - The invention provides an improved process for preparing unsaturated carboxylic anhydrides of the general formula I | 2010-03-18 |
20100069667 | PLASTIC CRYSTAL - The present invention relates to a conductor having high conductivity and electrochemical stability, which is in a solid state over a practically wide temperature range. Specifically disclosed is a plastic crystal containing a compound represented by Formula (I) or (IA) below: | 2010-03-18 |
20100069668 | 5-[(2R)-[2-[2-(2,2,2-TRIFLUOROETHOXY)PHENOXY]ETHYL]AMINO]PROPYL]-2-METHOXY- BENZENESULFONAMIDE - 5-[(2R)-[2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2-methoxybenzenesulfonamide, a pharmaceutical composition containing the compound, and the synthesis method thereof. The compound has strong antagonism toward α1-adrenceptor and has high selectivity toward smooth muscle of urethra. | 2010-03-18 |
20100069669 | Preparation of Iodixanol - A process for the preparation of iodixanol by dimerisation of 5-acetamido-N,N′-bis(2,3-dihydroxypropy1)-2,4,6-triiodo-isophthalamide (“Compound A”) in which, after the dimerisation step, unreacted Compound A is precipitated from the reaction mixture and recovered for re-use. The process substantially increases the net yield of iodixanol and simplifies its purification. | 2010-03-18 |
20100069670 | Oxidation catalyst - An oxidation catalyst for use in the oxidation of a substrate with a molecular oxygen, comprising at least one member selected from the group consisting of a specific hydrazyl radical (such as 2,2-diphenyl-1-picrylhydrazyl) and a specific hydrazine compound (such as 2,2-diphenyl-1-picrylhydrazine). A method for producing a chemical compound, comprising contacting a substrate with a molecular oxygen in the presence of the above-mentioned oxidation catalyst. | 2010-03-18 |
20100069671 | Process For Preparing Polyetheramines - The invention provides a process for preparing polyetheramines of the formula (1), R | 2010-03-18 |
20100069672 | HIGH FUNCTIONALITY AMINE COMPOUNDS AND USES THEREFOR - In another exemplary embodiment, an amine functional curing agent has an Amine Hydrogen Functionality (AHF) of at least 7 and an Amine-Hydrogen Equivalent Weight (AHEW) of at least about 50. | 2010-03-18 |
20100069673 | Neutralization of Ethylenediamine Hydrochloride and recovery of Ethylenediamine - In a neutralization and recovery process ethylene diamine hydrochloride (EDA-HCL) is neutralized and ethylene diamine (EDA) is recovered using a mixture of solid caustic dissolved in a non-aqueous solvent, for example an alcohol. | 2010-03-18 |
20100069674 | GARLIC PROCESSING - A method of producing polysulfides comprising the step of adding elemental sulphur to an allicin-containing plant extract. In preferred embodiments, the plant extract is mechanically treated members of the genus | 2010-03-18 |
20100069675 | SYNTHESIS OF [1-13C]PYRUVIC ACID], [2-13C]PYRUVIC ACID], [3-13C]PYRUVIC ACID] AND COMBINATIONS THEREOF - The present invention is directed to the labeled compounds, | 2010-03-18 |
20100069676 | PROCESS FOR MAKING TRANS-1-((1R,3S)-6-CHLORO-3-PHENYLINDAN-1-YL)-3,3-DIMETHYLPIPERAZINE - Described is a method for making the trans-1-((1R,3S)-6-chloro-3-phenylindan-1-yl)-3,3-dimethylpiperazine (formula I) and salts thereof and a similar method for making 4-((1R,3S)-6-chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine (formula IX) and salts thereof, which method comprises conversion of a compound of formula IVa to the compound of formula I or the compound of formula IX, respectively. | 2010-03-18 |
20100069677 | Method for Producing Cycloalkanol and/or Cycloalkanone - The present invention provides a method for producing cycloalkanol and/or cycloalkanone,
| 2010-03-18 |
20100069678 | HYDROFORMYLATION PROCESS - The disclosed is about a hydroformylation of a cyclic olefin with rhodium catalyst, and specifically about the recovering of the rhodium catalyst. Aldehyde and the cyclic olefin are added into a rhodium catalyst solution to process a hydroformylation, thereby forming the product cycloalkyl aldehyde. Afterwards, the result is divided into two layers. The upper layer is substantially rhodium catalyst solution, and the lower layer is substantially cycloalkyl aldehyde and the aldehyde. After separation, the upper layer is reserved to process next hydroformylation reaction with newly added cyclic olefin. | 2010-03-18 |
20100069679 | ACETYLENE TOLERANT HYDROFORMYLATION CATALYSTS - Hydroformylation catalysts which can tolerate high levels of alkyne impurities in an olefin feed stream. The catalysts are composed of rhodium in combination with fluorophosphite ligands or rhodium in combination with certain bidentate ligands. Propionaldehyde has been produced by the hydroformylation of ethylene streams containing up to 1000 parts per million of acetylene without any loss of activity due to the presence of the acetylene. Ethylene contaminated with acetylene at 10,000 ppm can also be converted to propionaldehyde but some loss of activity occurs. | 2010-03-18 |
20100069680 | HYDROFORMYLATION PROCESS WITH IMPROVED CONTROL OVER PRODUCT ISOMERS - A continuous hydroformylation process for producing a mixture of aldehydes with improved flexibility and stability of a normal/branched (N/I) isomer ratio of the product aldehydes. The process involves reacting one or more olefinically-unsaturated compounds with carbon monoxide and hydrogen in the presence of an organopolyphosphite ligand and an organomonophosphite ligand, at least one of such ligands being bonded to a transition metal to form a transition metal-ligand complex hydroformylation catalyst; the process being conducted at a sub-stoichiometric molar ratio of organopolyphosphite ligand to transition metal, at a super-stoichiometric (>2/1) molar ratio of organomonophosphite ligand to transition metal, and at a carbon monoxide partial pressure in the inverse order region of the hydroformylation rate curve; and controlling and varying the isomer ratio by varying the concentration of organopolyphosphite ligand relative to transition metal. | 2010-03-18 |
20100069681 | PROCESS FOR PREPARING 3-ALKOXYPROPAN-1-OLS - The present invention relates to a process for preparing 3-alkoxypropan-1-ols of the general formula I | 2010-03-18 |
20100069682 | PREPARATION OF PURIFIED HYDROQUINONE - Hydroquinone devoid of impurities is prepared from a crude hydroquinone essentially containing hydroquinone and small amounts of impurities including at least resorcinol, pyrogallol and traces of pyrocatechol and comprises at least the following steps: dissolving the crude hydroquinone in water, crystallizing the hydroquinone, separating the purified hydroquinone, and, optionally, drying the purified hydroquinone. | 2010-03-18 |
20100069683 | Organic metal compound and process for preparing optically-active alcohols using the same - The present invention provides an asymmetric reduction catalyst effective in preparing optically-active alcohol compounds having various functional groups, and a process for preparing optically-active alcohol compounds using said asymmetric reduction catalyst. | 2010-03-18 |
20100069684 | ASSYMMETRIC HYDROGENERATION OF PROCHIRAL COMPOUNDS - The invention relates to the asymmetric (transfer) hydrogenation of a prochiral keton, prochiral imine, oxime, oxime derivative, hydrazone or hydrazone derivative, using a transition metal catalyst, characterized in that as a catalyst is used a transition metal complex of the general formula [I]: M | 2010-03-18 |
20100069685 | PROCESS FOR PRODUCING PRODUCT OF HYDROGENOLYSIS OF POLYHYDRIC ALCOHOL - The present invention relates to a process for producing a hydrogenolysis product of a polyhydric alcohol with a high selectivity and high efficiency using a specific catalyst, as well as to a catalyst for hydrogenolysis of a polyhydric alcohol used in the process. | 2010-03-18 |
20100069686 | Energy Efficient Separation of Ethanol From Aqueous Solution - The present invention provides methods and systems for extracting ethanol from an ethanol-water solution comprising (1) extracting ethanol from an ethanol-water solution with a first solvent comprising an esterified fatty acid, wherein the esterified fatty acid comprises a hydroxylated fatty acid component and an alcohol component such that the alcohol component is a C | 2010-03-18 |
20100069687 | PROCESS FOR SYNTHESIS OF POLYALPHAOLEFIN AND REMOVAL OF RESIDUAL CATALYST COMPONENTS - A process for reducing the level of residual catalyst comprising one or more 1-halo-2-methylpropanes and a Group 13 metal catalyst from a crude polyolefins product, the process comprising contacting the crude organic product with a solid adsorbent in an adsorbent system. Also provided is a co-catalyst system for polymerizing alpha olefins. | 2010-03-18 |
20100069688 | MICROWAVE PROCESSING OF CARBON-BASED COMPOSITIONS - The present invention provides methods for decomposing and extracting compositions for the recovery of petroleum-based materials from composites comprising those petroleum-based materials, comprising subjecting the compositions and/or composites to microwave radiation, wherein the microwave radiation is in the range of from about 4 GHz to about 18 GHz. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention. | 2010-03-18 |
20100069689 | Process and System for Providing Acetylene - A system and a process for providing acetylene, preferably at a high purity level (e.g., comprising 100 parts per million (“ppm”), or 10 ppm, or 1 ppm, or 100 parts per billion (“ppb”), or 10 ppb, or 1 ppb or less of solvent), to a point of use, such as a semiconductor manufacturing process, is described herein. In one aspect, there is provided a process for providing a process for providing a high purity acetylene comprising 100 ppm or less solvent to a point of use comprising: providing an acetylene feed stream comprising acetylene and solvent at a temperature ranging from 20° C. to −50° C.; and introducing the acetylene feed stream to a purifier at a temperature ranging from −50° C. to 30° C. to remove at least a portion of the solvent contained therein and provide the high purity acetylene. | 2010-03-18 |
20100069690 | HYDROGENATION PROCESS - A process comprising reacting hydrogen and a reaction composition comprising a carboxylic acid and/or derivative thereof in a reactor to produce a reaction composition comprising one or more C | 2010-03-18 |
20100069691 | METHOD FOR THE PRODUCTION OF ONE OR MORE OLEFINS, AN OLEFIN, AND A POLYMER - The present invention describes a method for the production of one or more olefins from the residue of at least one renewable natural raw material. The present invention is advantageously related to a method that is integrated with a processing method for processing renewable natural agricultural raw materials for the production of propylene, and optionally of ethylene and butylene, mainly from the residues of the processed renewable natural agricultural raw material. The propylene is obtained from the gasification reaction of the lignocellulosic materials and of other organic products contained in the raw material residues, followed by the formation of methanol and its subsequent transformation into propylene, where this route may further generate ethylene and/or butylene as by-products. | 2010-03-18 |
20100069692 | Solid Phosphoric Acid with controlled porosity - The present invention relates to a solid phosphoric acid catalyst and a process for conversion of hydrocarbons using a solid phosphoric acid catalyst. The solid phosphoric acid catalyst comprises silicon orthophosphate, and has a silicon orthophosphate to silicon pyrophosphate ratio of at least about 5:1. The total pore volume of the solid phosphoric acid catalyst is at least about 0.17 cm | 2010-03-18 |
20100069693 | Liquid Phase Alkylation with Multiple Catalysts - A process is disclosed for producing an alkylaromatic compound in a multistage reaction system comprising at least first and second series-connected alkylation reaction zones, each containing an alkylation catalyst. A first feed comprising an alkylatable aromatic compound and a second feed comprising an alkene are introduced into the first alkylation reaction zone. The first and second alkylation reaction zones are operated under conditions of temperature and pressure effective to cause alkylation of the aromatic compound with the alkene in the presence of the alkylation catalyst, the temperature and pressure being such that the aromatic compound is at least partly in the liquid phase. The alkylation catalyst in the first alkylation reaction zone, which may be a reactor guard bed, has more acid sites per unit volume of catalyst than the alkylation catalyst in the second reaction zone. | 2010-03-18 |
20100069694 | Xylene Isomerization Process and Apparatus - Xylene isomerization processes, especially those processes in which ethylbenzene is also converted, are beneficially affected by adding benzene to the feed. | 2010-03-18 |
20100069695 | ADDITIVE FOR REDUCING COKING AND/OR CARBON MONOXIDE IN CRACKING REACTORS AND HEAT EXCHANGERS AND USE OF SAME - The present invention concerns an additive for reducing the formation of coke and/or carbon monoxide in thermal hydrocarbon cracking units and/or of other organic compounds in heat exchangers. The additive according to the invention is essentially composed of diethyl disulphide (DEDS) or dipropyl disulphide(s) (DPDS) or dibutyl disulphide(s) (DBDS) and can be used on the metal walls of a cracking reactor and on the metal walls of a heat exchanger placed downstream from the cracking reactor, and during the process of cracking hydrocarbons and/or other organic compounds. | 2010-03-18 |
20100069696 | PROCESS FOR SEPARATING PROPYLENE MIXED WITH PROPANE BY ADSORPTION IN A SIMULATED MOVING BED - A process for separating propylene mixed with propane by adsorption in a simulated moving bed is described. The process operates in the gaseous phase or in the liquid phase, and it uses a 13X faujasite-type zeolite as adsorbent solid and butene-1 or isobutane or any mixture of these 2 components as desorbent. | 2010-03-18 |
20100069697 | Radioactive Material Sequestration - A radioactive material sequestration system may include a radionuclide containment composition dispenser and a sorption based media container. The radionuclide containment composition dispenser may be configured for holding a radionuclide containment composition and be capable of dispensing the radionuclide containment composition to remove radionuclides from a radioactive material. The radionuclide containment composition is a mixture of a clay mineral and water. The sorption based media container may be configured for holding a sorption based media; receiving dispensed radionuclide containment composition; and sequestering the radionuclides. The radioactive material sequestration system may also include a probe. | 2010-03-18 |
20100069698 | TREATMENT OF NUCLEAR SLUDGE - A method for treating nuclear sludge comprising subjecting the nuclear sludge to a plasma treatment in a plasma chamber to melt at least some of the inorganic components of the sludge, wherein the plasma chamber comprises a crucible having a cooled inner surface, this surface cooled sufficiently such that the inorganic components in contact with the inner surface are in a solid state and form a barrier between the part of surface of the crucible with which they are in contact and the molten inorganic components of the sludge. | 2010-03-18 |
20100069699 | Medical Waster Disposal Apparatus - A medical waste disposal apparatus for receiving and retaining waste articles, such as catheter fittings, and the like, for controlled and facilitated handling and disposal of such waste articles, during and following the performance of treatment procedures on a patient by a practitioner. The waste disposal apparatus includes a first retaining member, mounted on a base panel, for receiving and retaining a waste article placed there by a practitioner during a treatment procedure, and further includes at least one side panel, for covering the waste article, after placement of the waste article on the first retaining member. Alternative configurations of retaining members are provided. | 2010-03-18 |
20100069700 | METHOD AND DEVICE FOR EVAPORATE/REVERSE OSMOSIS CONCENTRATE AND OTHER LIQUID SOLIDIFICATION - A Method and Device for solidification of waste liquids and fluids is disclosed, which is particularly well suited to processing radioactive waste fluids. Set forth is a receiving unit or subassembly for housing solidification agent, and one or more manifold units or subassemblies positioned within the receiving unit for providing waste fluid. The subassemblies operate in relation to each other to provide, position and mix solidification agent or polymer with waste fluid so that a dirt-like polymerized waste product is produced and positioned in the container for removal or later safe shipment or storage. Mathematical relationships, in preferred embodiments or aspects are utilized in determining number and sizing of manifold openings, and pressure of waste to be provided, to meet the requirements of waste fluids to be transported through these openings into the receiving unit. | 2010-03-18 |
20100069701 | METHOD FOR DISASSEMBLING A SPRAY DRYING SYSTEM - The present invention relates to a spray drying system provided with a neutralizing system, which system is intended for use in the pharmaceutical industry or in other industries, where the product is e.g. infectious, toxic or highly reactive and constitutes a risk for the surroundings and/or a health risk to people handling the product. The spray drying system comprises a spray drying chamber ( | 2010-03-18 |
20100069702 | METHOD OF CHEMICAL TREATMENT OF SOILS CONTAINING HAZARDOUS SUBSTANCES SUSCEPTIBLE TO NUCLEOPHILLIC ATTACK - A method for remediating hazardous materials susceptible to nucleophillic attack is disclosed wherein sodium hydroxide is applied to a treatment zone in situ for raising the pH of the treatment zone to at least about 12.5 so that alkaline hydrolysis effectively breaks down the hazardous substance by replacing a leaving group with a nucleophile. The method is well suited for in situ use in the vadose zone to treat contaminated soil and groundwater. | 2010-03-18 |
20100069703 | BIOPHYSIOLOGICAL REGULATOR FOR THERAPEUTIC TREATMENTS - The invention relates to a biophysiological regulator for therapeutic treatments, including brain stimulation coils ( | 2010-03-18 |
20100069704 | SYSTEMS AND METHODS FOR INDUCING ELECTRIC FIELD PULSES IN A BODY ORGAN - Systems and methods for providing controllable pulse parameter magnetic stimulation are described. One aspect is directed to a magnetic stimulation system for inducing approximately rectangular electric field pulses in a body organ, comprising an electrical energy storage device, a stimulating coil, and a switching means for electrically coupling said electrical energy storage device to said stimulating coil to produce current pulses in said stimulating coil which generates, in response to the current pulses, magnetic field pulses that can induce approximately rectangular electric field pulses in the body organ. | 2010-03-18 |
20100069705 | HEARING ASSISTANCE DEVICE HAVING REDUCED MECHANICAL FEEDBACK - An electronic hearing aid apparatus comprises a first component, a second component and a cable assembly for electrically connecting the first component to the second component. The first component includes a vibration sensor for sensing acoustic vibrations and generating a vibration signal based on the sensed acoustic vibrations, electronics for processing and amplifying the vibration signal and an output port for providing access to the amplified vibration signal. The second component includes an input port for receiving the amplified vibration signal and a vibration generator for generating vibrations based on the amplified vibration signal. The cable assembly conducts the amplified vibration signal from the output port of the first component to the input port of the second component. The cable assembly includes a first connector for electrically connecting to the first component, a second connector for electrically connecting to the second component and a flexible cable portion for electrically connecting the first connector to the second connector. In some embodiments, the cable portion has a stiffness of no more than about 7.0 Taber stiffness units. In one most preferred embodiment, the cable portion has a stiffness of no more than about 1.0 Taber stiffness unit. | 2010-03-18 |
20100069706 | ARTIFICIAL VAGINA FOR THE COLLECTION OF ANIMAL SEMEN - The artificial vagina for the collection of animal semen includes two half-shells capable of being positioned with regard to one another in order to form a tubular shell, said shell being rigid and open at its two extremities. A half-sleeve is accommodated inside each half-shell, in such a manner that once the two half-shells are positioned with regard to one another in order to form said shell, the two half-sleeves form a tubular housing that is suitable for receiving the penis of an animal, said housing being soft and capable of elastic deformation in a radial direction. At least one of the half-shells includes a lateral opening that allows radial pressure to be exerted manually through the half-shell onto the corresponding half-sleeve. | 2010-03-18 |
20100069707 | GASTRIC BAND WITH POSITION SENSING - The problem of accessing an injection port transcutaneously is resolved using wireless position transducers in an inflation port assembly and in an injection syringe. The measurements provided by the transducers indicate to the practitioner the position and orientation of syringe relative to the injection port. A console provides a visual indication of the relative position and orientation so as to guide the practitioner to insert the syringe at the proper site and in the proper direction and to penetrate the port cleanly and correctly. | 2010-03-18 |
20100069710 | TREATMENT METHOD - A treatment method for a tissue in a body cavity of a patient includes the steps of endoscopically introducing treatment tools into the body cavity of the patient from a natural opening of the patient, and setting the posture of the patient to a prone position. | 2010-03-18 |
20100069711 | Self-sealing control arrangement for a medical instrument - A control arrangement for use in a medical or surgical instrument, which arrangement includes a keypad for providing manual control functions to a user of the instrument, a retainer clip and a sealing member. The keypad and retainer clip are located within an opening formed in the instrument housing, whereby when the retainer clip is assembled to the housing, the retainer clip automatically causes the sealing member to sealingly engage with a corresponding sealing surface defined adjacent the housing opening, without the need for the use of additional sealing agents. | 2010-03-18 |
20100069712 | MOTHER-BABY ENDOSCOPE - A mother-baby endoscope includes: a lateral-view mother endoscope housing a treatment instrument raising stand in a distal end portion and including a treatment instrument insertion channel disposed in an insertion portion and opening toward the treatment instrument raising stand; and a baby endoscope including an insertion portion having a bending portion disposed on a distal end side, the insertion portion being inserted into the treatment instrument insertion channel of the mother endoscope and guided into a body cavity for observing or treating a region to be inspected. When the insertion portion of the baby endoscope is protruded by approximately 20 millimeters from an observation window of the mother endoscope in an observation direction, a proximal end surface of the bending portion of the baby endoscope is set to be located on a more proximal end side than an opening portion of the treatment instrument insertion channel. | 2010-03-18 |