13th week of 2013 patent applcation highlights part 45 |
Patent application number | Title | Published |
20130078642 | BIOMARKERS FOR LUNG NEUROENDOCRINE TUMORS - The present invention regards a method for providing a diagnosis for small cell lung carcinoma and for typical carcinoid tumor by using a panel of protein biomarkers which are differentially expressed and a method for screening compounds. | 2013-03-28 |
20130078643 | DEVICE AND METHOD OF DETECTING TSH - A device for detecting the concentration of biological materials, is formed in a body having a plurality of fluidic paths connectable to a multi-microbalance structure carrying a plurality of microbalances, each microbalance having a sensitive portion facing a reaction chamber. The body and the multi-microbalance structure are configured to be mechanically coupled together and each microbalance is configured to be coupled to a respective fluidic path. Each fluidic path includes an inlet, a duct and a liquid waste, each duct being configured to be coupled with a respective reaction chamber. The plurality of fluidic paths and microbalances form at least one first and one second reference cells and one first sample cell. | 2013-03-28 |
20130078644 | Post-Translational Modifications Identified by Elemental Analysis - Methods and kits for enzymes involved in post-translational modifications are provided. The methods employ elemental analysis, including ICP-MS. The methods allow for the convenient and accurate analysis of post-translation modifications of substrates by enzymes involved in post-translational modifications, including kinase and phosphatase enyzmes | 2013-03-28 |
20130078645 | BIOMARKERS - The invention relates to a method of diagnosing or monitoring schizophrenia or other psychotic disorder. The biomarkers used are selected from cyclophilin A, cytosalic non-specific dipepditase, Caoctosin-like protein, Glucose-6-phosphate isomerase, uncharacterized protein KIAA0423, myosin 14, myosin 15, nicotinamide phosphoribosyltransferase, pyruvate kinase isozyme R/L, phosphoglyterate mutase 4. | 2013-03-28 |
20130078646 | ANTIBODIES, COMPOSITIONS, AND ASSAYS FOR DETECTION OF CARDIAC DISEASE - The present invention provides antibodies, devices, and immunoassays for detection of ischemic cardiac events (unstable angina and heart attack) in patients experiencing chest pain. The invention allows for rapid determination of the cause of chest pain, and allows for differentiation of chest pain due to ischemic cardiac events and other causes. The invention provides antibodies that specifically bind to the epitope f-MII and the epitope f-MLF. | 2013-03-28 |
20130078647 | Methods of Detection of Changes in Cells - Methods are provided to detect changes in cells without the use of detection labels. | 2013-03-28 |
20130078648 | DIRECT EXAMINATION OF BIOLOGICAL MATERIAL EX VIVO - The present invention relates to a method for the visual examination of biological material ex vivo and an apparatus for the sterical orientation of biological material which can be used in said method. | 2013-03-28 |
20130078649 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY AND DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL - The present invention concerns combination of an amount of a BRS-3 agonist with an amount of a dipeptidyl peptidase IV (DPP-IV) inhibitor such that the combination provides an effect in lowering a blood glucose level or in increasing a blood GLP-1 level in a subject over that provided by the amount of the BRS-3 agonist alone and by the amount of the DPP-IV inhibitor alone and the use of such a combination for treating or preventing obesity and diabetes and conditions related thereto and conditions ameliorated by increasing a blood GLP-1 level. The present invention also relates to the use of a G protein-coupled receptor to screen for GLP-1 secretagogues. | 2013-03-28 |
20130078650 | IDENTIFYING MATERIAL FROM A BREAST DUCT - Methods and systems for identifying material from a breast duct using one or more markers that can be identified in ductal fluid retrieved from the breast are provided. | 2013-03-28 |
20130078651 | INDIVIDUAL INFORMATION DETERMINING METHOD, INDIVIDUAL INFORMATION DETERMINING DEVICE, ELECTRONIC APPARATUS, AND INDIVIDUAL INFORMATION DETERMINING PROGRAM - Disclosed in an individual information determining method in which individual information of a subject is determined based on one or a plurality of pieces of biomolecule data collected from a surface of a body surface of the subject. | 2013-03-28 |
20130078652 | METHODS AND KITS FOR DETERMINING VON WILLEBRAND FACTOR ACTIVITY IN THE ABSENCE OF RISTOCETIN AND FOR DETERMINING THE ACTIVITY OF ADAMTS-13 PROTEASE - Described herein are method(s), kit(s), reagent(s) and the like for determining von Willebrand factor (VWF) activity in a sample in the absence of ristocetin. | 2013-03-28 |
20130078653 | ANTIBODIES, COMPOSITIONS, AND ASSAYS FOR DETECTION OF CARDIAC DISEASE - The present invention provides antibodies, devices, and immunoassays for detection of ischemic cardiac events (unstable angina and heart attack) in patients experiencing chest pain. The invention allows for rapid determination of the cause of chest pain, and allows for differentiation of chest pain due to ischemic cardiac events and other causes. The invention provides antibodies that specifically bind to the epitope f-MII and the epitope f-MLF. | 2013-03-28 |
20130078654 | Methods For Diagnosing Rheumatoid Arthritis - The present invention relates to methods of diagnosing, prognosing, preventing or delaying onset of or treating rheumatoid arthritis, methods of distinguishing between different types or stages of rheumatoid arthritis, of identifying an individual at risk of developing rheumatoid arthritis, and of monitoring efficacy of a treatment regime in an individual being treated for rheumatoid arthritis, using a citrullinated enolase peptide to detect or capture antibodies associated with rheumatoid arthritis. | 2013-03-28 |
20130078655 | KIDNEY PROGNOSTIC ASSAY - The invention provides a method of predicting subjects at risk of loss of kidney function and/or identifying subjects at greater risk of loss of kidney function, and/or identifying subjects at risk of kidney failure/end stage kidney disease, the method comprising detecting an amount of free light chains (FLC) in a sample from the subject, wherein a higher amount of FLC is associated with increased risk of loss of kidney function and/or increased risk of renal failure/end stage kidney disease. A further aspect of the invention provides a method of monitoring renal impairment, comprising detecting an amount of free light chains (FLC) in a sample from a subject having renal impairment and comparing the amount of FLC in the sample with an Total FLC amount of FLC detected in a sample previously obtained from the subject, wherein an increase in the amount FLC detected, compared to the previous sample, indicates an increase in the risk of loss of renal function in the subject, and a decrease in the amount of FLC indicates a decrease in the risk of loss of renal function in the subject. | 2013-03-28 |
20130078656 | ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system. | 2013-03-28 |
20130078657 | HYPERTHERMIA AUGMENTED IN-VITRO IMMUNE RECOGNITION - The present invention relates to a method for generation of a test-antigen specific cell-mediated immune response by incubating at hyperthermic conditions and, more particularly, a method for generation of a test-antigen specific cell-mediated immune response by incubating at hyperthermic conditions and optionally adding IL-7 and/or blocking IL-10. Even more particularly, the present invention provides a method for generating a cell-mediated response to an antigen using whole blood or other suitable bio-logical samples. The method is useful in for immune diagnosis of many infectious diseases, as a marker of immunocompetence, and for detection of T-cell responses to non-self antigens (i.e. infections and vaccines). | 2013-03-28 |
20130078658 | METHOD OF QUANTIFYING RECOVERY RATE OF EXOSOME - A recombinant exosome comprising a fusion protein of a membrane protein and light-emitting protein, and a method of determining an exosome recovery rate by using the recombinant exosome are provided. Use of the method ensures accurate quantification of exosomes in a sample, and thus, improves the efficiency of an exosome-based diagnosis. | 2013-03-28 |
20130078659 | METHOD FOR QUANTITATIVELY DETERMINING LDL CHOLESTEROLS - A method for quantitatively determining LDL cholesterol, including the steps of adding to serum a surfactant selected from among polyoxyethylenealkylene phenyl ethers and polyoxyethylenealkylene tribenzylphenyl ethers and a cholesterol-assaying enzyme reagent so as to preferentially react cholestrols in high density- and very low density-cholesterols among lipoproteins, and subsequently determining the amount of cholesterol that reacts thereafter. This method can eliminate the necessity for pretreatments such as centrifugation and electrophoresis, enables the quantitative determination to be conducted in an efficient, simple manner, and can be applied to various automatic analyzers. | 2013-03-28 |
20130078660 | METHODS AND COMPOSITIONS FOR DETECTING PROTEIN MODIFICATIONS - Methods and compositions for detecting a protein modification in vitro and in vivo are disclosed. In certain embodiments, the protein modification detected is phosphorylation. | 2013-03-28 |
20130078661 | Compounds and Methods for FRET Based Measurement of Enzyme Activity - Provided are compositions and methods for Fluorescence/Forster Resonance Energy Transfer (FRET) analysis of cleavage of Von Willebrand Factor (VWF) polypeptides by the metalloprotease ADAMTS13. The polypeptides contain: i) a first fluorescent protein ii) a VWF amino acid sequence and iii) a second fluorescent protein. The VWF amino acid can contain any of a variety of amino acid substitutions. The method involves contacting a sample that contains ADAMTS13 and using FRET based measurements to determine ADAMTS13 cleavage of the recombinant polypeptide. | 2013-03-28 |
20130078662 | Bacillus Pumilus Bilirubin Oxidase and Applications Thereof - The present invention relates to a novel | 2013-03-28 |
20130078663 | Pore-Limit Electrophoresis (PLE) Microchannel Assays - Pore-limit electrophoresis (PLE) microchannel assay methods are provided. Aspects of the methods include sequentially introducing samples at least suspected of containing first and second assay members into a PLE microchannel and then evaluating the microchannel for interaction between the first and second assay members. Aspects of the invention further include devices, systems and kits configured for practicing methods of invention. The methods, devices, systems and kits of the invention find use in a variety of different applications, including enzyme activity assays and immunoassays. | 2013-03-28 |
20130078664 | METHODS FOR ASSAYING PERCENTAGE OF GLYCATED HEMOGLOBIN - The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The methods utilizes one or two different types of oxidizing agents which selectively oxidize low-molecular weight reducing substances and high-molecular weight (mainly hemoglobin) reducing substances in blood samples, coupled with enzymatic reactions catalyzed by proteases, fructosyl amino acid oxidase. The amount of hydrogen peroxide generated in the reaction is measured for determination of percentage of glycated hemoglobin in blood samples. The invention provides kits for performing the methods of the invention. | 2013-03-28 |
20130078665 | Test strip, a test kit and a method for detection of endotoxin in food - A home test strip for detection of endotoxin in food, the test strip includes an amebocyte lysate component, a chromogenic substrate component, and a carrier matrix. The amebocyte lysate component and the chromogenic substrate component are located in close proximity to each other and further incorporated within the carrier matrix. A home test kit for detection of endotoxin in food is also provided, which includes a sample holding container for collecting and holding a sample, a test strip, a standard colour scale. A method for detection of endotoxin in food is further provided, which includes the steps of preparing a food sample, placing a test strip in the food sample, waiting for an instructed time prior to removing the test strip, observing the formation of any colour, and matching the intensity of colour formed against a standard colour scale for deciding safety of food for consumption. | 2013-03-28 |
20130078666 | SCAFFOLD-BASED ORGANOTYPIC CULTURE FOR THE LONG-TERM CULTIVATION OF HUMAN EPIDERMAL STEM CELLS - The present invention relates to organotypic cultures of epidermal cells and the use thereof for the screening of pharmaceutical and cosmetic agents. Specifically, means for the improvement of the long-term stability of such cultures are disclosed. Thus, the present invention contemplates a skin equivalent comprising (a) a dermal equivalent comprising a matrix comprising nonwoven viscose fabric and fibroblasts and (b) keratinocytes. Moreover, the present invention contemplates a method for manufacturing the skin equivalent and a method for screening agents capable of influencing skin, such as a therapeutic or cosmetic agent. | 2013-03-28 |
20130078667 | METHODS FOR DETECTING AND COLLECTING CIRCULATING TUMOR CELLS - The present invention is directed towards methods of expanding circulating tumor cell populations and methods of detecting circulating tumor cells in a sample. | 2013-03-28 |
20130078668 | METHOD AND APPARATUS FOR DETECTING THE PRESENCE OF INTRAERYTHROCYTIC PARASITES - An apparatus and method for determining the presence of an intraerythrocytic organism within a sample of liquid whole blood is provided. The method includes the steps of a) creating an image of the sample quiescently residing within a sample chamber; b) evaluating the image for the presence of at least one red blood cell within the image containing at least one first region of decreased hemoglobin content and/or hemoglobin concentration within the red blood cell, which red blood cell has an otherwise homogenous distribution of hemoglobin; and c) determining the presence of an intraerythrocytic organism within the sample using the evaluation of the image. | 2013-03-28 |
20130078669 | Method And Devices For The Cross-Referencing Of Identification Of Tissue Slice Supports For Microtomised Analytical Samples - The invention relates to a method and device for the cross-referencing of identification ( | 2013-03-28 |
20130078670 | MICROTOME SECTIONABLE BIOPSY SUPPORT FOR ORIENTING TISSUE SAMPLES - Tissue orientation devices include a perforated tissue support with at least one perforated channel for receiving a tissue sample, and a plurality of tabs configured to extend along and into the channel to retain the tissue sample during processing and embedding. Tissue orientation devices include elongated legs coupled together for holding one or more biopsy tissue samples therebetween. Associated methods include using the cassettes and orientation devices to hold and orient tissue samples for processing, embedding and microtome sectioning. | 2013-03-28 |
20130078671 | INCORPORATION OF TWO DIFFERENT NONCANONICAL AMINO ACIDS INTO A SINGLE PROTEIN - The invention relates to methods, systems, and compositions for the genetic incorporation of a plurality of different noncanonical amino acids into one target protein. The invention provides for multiple, mutually orthogonal aminoacyl-tRNA synthetase/tRNA pairs that suppress two different selector codons engineered into a polynucleotide molecule. By virtue of the suppression of the selector codons, orthogonal aminoacyl-tRNA synthetase/tRNA pairs permit incorporation of their charged noncanonical amino acids into the corresponding positions in the protein. The noncanonical amino acids provide a wide array of functional capabilities. For example, the noncanonical amino acids can provide a reactive pair of moieties that facilitate the study and manipulation of the target protein. | 2013-03-28 |
20130078672 | POLYPEPTIDES HAVING XYLANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to isolated polypeptides having xylanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 2013-03-28 |
20130078673 | RECOMBINANT MICROORGANISM HAVING AN ABILITY OF USING SUCROSE AS A CARBON SOURCE - The present invention relates to a recombinant microorganism capable of metabolizing sucrose, and more particularly to a recombinant microorganism capable of metabolizing sucrose in which a gene encoding sucrose phosphotransferase and/or a gene encoding sucrose-6-phosphate hydrolase is introduced or to a recombinant microorganism capable of metabolizing sucrose in which a gene encoding β-fructofuranosidase is introduced. According to the present invention, a recombinant microorganism capable of using inexpensive sucrose as a carbon source instead of expensive glucose is provided. In addition, in a process of culturing microorganisms which have been incapable of using sucrose as a carbon source, sucrose can substitute for other carbon sources including glucose. | 2013-03-28 |
20130078674 | Method for protein production in filamentous fungi - The present invention relates to a method for genetically modifying a filamentous fungus host for improved protein production. The method comprises that a filamentous fungus host is genetically modified to overexpress or to be deficient of specific genes. The invention relates also to the modified hosts. Furthermore, the invention relates to a method for improved production or for producing an improved composition of proteins, such as cellulases, hemicellulases, other proteins involved in the degradation of lignocellulosic material, or other proteins, in a filamentous fungus host. | 2013-03-28 |
20130078675 | HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN IL-4 RECEPTOR - The present invention provides nucleic acid molecules that encode antibodies or antigen-binding fragments thereof, which specifically bind human interleukin-4 receptor (IL-4R). Also provided are expression vectors comprising nucleic acid molecule that encode anti-IL-4R antibodies, host cells comprising the expression vectors, and methods of producing anti-IL-4R antibodies or antigen-binding fragments thereof comprising growing the host cells under conditions permitting production of the antibody or fragment, and recovering the antibody or fragment so produced | 2013-03-28 |
20130078676 | METHOD OF REGULATING OLIGONUCLEOTIDE FUNCTIONALITY - The present invention relates generally to a method of regulating oligonucleotide functionality and, more particularly, to a method of regulating the functionality of a primer or probe. The method of the invention is designed to provide a means to selectively inactivate or activate the functionality of an oligonucleotide, such as a primer, thereby providing means to regulate the progress of any method using that oligonucleotide. The development of a means to regulate the functionality of an oligonucleotide, such as a primer, is useful in a range of applications including, but not limited to, amplification reactions such as PCR, isothermal amplification and nucleic acid strand extension. With respect to amplification reactions, these have wide utility including the diagnosis and/or monitoring of disease conditions which are characterised by specific gene sequences and the characterisation or analysis of specific gene regions of interest. | 2013-03-28 |
20130078677 | PROCESS FOR THE PRODUCTION OF CARBOHYDRATE CLEAVAGE PRODUCTS FROM A LIGNOCELLULOSIC MATERIAL - A process for the production of carbohydrate cleavage products, characterized by a combination of the measures that a lignocellulosic material is treated with an aqueous solution containing an alcohol, in particular a C | 2013-03-28 |
20130078678 | Protozoan Glycosidases and Related Methods - Nucleic acids encoding glycosidases useful for the hydrolysis of cellulose and hemicellulose obtained from ciliates residing in a bovine rumen are provided. Also provided recombinant nucleic acids encoding the glycosidases, transformed cells comprising the same and related methods of using the transformed cells and glycosidases to degrade cellulose and/or hemicellulose. | 2013-03-28 |
20130078679 | Polypeptides Having Cellobiohydrolase 1 Activity and Polynucleotides Encoding Same - The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. | 2013-03-28 |
20130078680 | METHOD FOR PRODUCTION OF FERMENTABLE SUGARS FROM BIOMASS - A process for production of fermentable sugars from biomass using multi-enzyme multi-step system is provided herein. The process disclosed in the present invention provides high yielded sugars in less time period. The multi-enzyme system disclosed in the present invention converts celluloses, hemicelluloses and/or mixture thereof to fermentable sugar with higher efficiency and better economics than the process known in the prior art. Cellulose and hemicelluloses fractions derived from natural sources such as any lignocellulosic biomass are saccharified in a shortened time with higher conversion rates of intermediates with modified enzymatic compositions/groups of the Multi-enzyme system to enhance the rate thus providing an economical cellulose and hemicellulose saccharification process. | 2013-03-28 |
20130078681 | METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF THE ENTEROBACTERIACEAE FAMILY HAVING ATTENUATED EXPRESSION OF GENES ENCODING A LYSINE/ARGININE/ ORNITHINE TRANSPORTER - The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus | 2013-03-28 |
20130078682 | Method for Producing an L-Amino Acid Using a Bacterium of the Enterobacteriaceae Family, Having Attenuated Expression of Gene(s) Encoding Peptidase - The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus | 2013-03-28 |
20130078683 | Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof - The present invention provides for a method of producing a cinnamoyl anthranilate, or analog thereof, in a genetically modified host cell. | 2013-03-28 |
20130078684 | ACYL-ACP WAX ESTER SYNTHASES - The invention relates to acyl-CoA-independent methods of producing a wax ester in recombinant host cells engineered to express an acyl-ACP wax ester synthase, and an alcohol-forming acyl-ACP reductase. The methods of the invention may take place in photosynthetic microorganisms, and particularly in cyanobacteria. Isolated nucleotide molecules and vectors expressing an acyl-ACP wax ester synthase and/or an alcohol-forming acyl-ACP reductase, recombinant host cells expressing an acyl-ACP wax ester synthase and optionally an alcohol-forming acyl-ACP reductase, and systems for producing a wax ester via an acyl-CoA-independent pathway, are also provided. | 2013-03-28 |
20130078685 | OZONOLYSIS OF UNSATURATED FATTY ACIDS AND DERIVATIVES THEREOF - The invention relates to a method for the ozonolysis of unsaturated fatty acids and derivatives thereof, comprising a) ozonolysis of a fatty acid or of a derivative thereof in an organic phase comprising an organic solvent, and b) contacting the organic phase with an aqueous phase comprising catalase and preferably a buffer, where the fatty acid or the derivative thereof has a linear chain having at least eight carbon atoms, and the use of catalase for removing reactive oxygen species from a reaction mixture comprising ozonolysis products of an unsaturated fatty acid. | 2013-03-28 |
20130078686 | PRODUCTION AND SECRETION OF FATTY ACIDS AND FATTY ACID DERIVATIVES - The invention relates to acyl-CoA-independent methods of producing fatty alcohols in recombinant host cells engineered to express an alcohol-forming acyl-ACP reductase. The recombinant host cells may be photosynthetic microorganisms, such as cyanobacteria. Isolated nucleic acid molecules, vectors, and recombinant host cells expressing an alcohol-forming acyl-ACP reductase, and systems for producing fatty alcohols via an acyl-CoA-independent pathway, are also provided. Also provided are microorganisms engineered for the secretion of fatty acids and fatty acid derivatives, including fatty alcohols, and methods of producing fatty acid derivatives using such engineering microorganisms. | 2013-03-28 |
20130078687 | FROM CARBON MONOXIDE AND HYDROGEN ANAEROBIC FERMENTATION PROCESSES USING A PRE-REACTOR/DEEP TANK REACTOR SYSTEM - Processes are disclosed for the low energy, anaerobic bioconversion of hydrogen and carbon monoxide in a gaseous substrate stream to oxygenated organic compounds such as ethanol by contact with microorganisms in a fermentation system with high conversion efficiency of both hydrogen and carbon monoxide. The processes of this invention use a pre-reactor and a deep, tank reactor in gaseous substrate flow sequence to obtain high conversion of gas substrate without undue risk of carbon monoxide inhibition. | 2013-03-28 |
20130078688 | LOW ENERGY, HIGH SUBSTRATE EFFICIENCY, ANAEROBIC, DEEP, BUBBLE COLUMN FERMENTATION PROCESSES - Bioconversion processes are disclosed that enable high conversion efficiencies of gas substrate containing both carbon monoxide and hydrogen to oxygenated organic compounds via the carbon monoxide and hydrogen pathways using anaerobic, deep, bubble column fermentation in a cost effective manner. The high conversion efficiency processes of this invention comprise the combination of using at least two deep, bubble column reactors in flow series and using certain feed gas compositions and microbubbles while avoiding carbon monoxide inhibition. | 2013-03-28 |
20130078689 | PROCESSES FOR ENHANCING THE PERFORMANCE OF LARGE-SCALE, STIRRED TANK ANAEROBIC FERMENTORS AND APPARATUS THEREFOR - Processes and apparatus are disclosed for the low energy, anaerobic bioconversion of hydrogen and carbon monoxide in a gaseous substrate stream to oxygenated organic compounds such as ethanol by contact with microorganisms in a deep, stirred tank fermentation system with high conversion efficiency of both hydrogen and carbon monoxide. Gas feed to the reactor is injected using a motive liquid to form a stable dispersion of microbubbles thereby reducing energy costs, and a portion of the off-gases from the reactor are recycled to (i) achieve a conversion of the total moles of carbon monoxide and hydrogen in the gas substrate to oxygenated organic compound of at least about 80 percent and (ii) attenuate the risk of carbon monoxide inhibition of the microorganism used for the bioconversion. | 2013-03-28 |
20130078690 | BIOLOGICAL AND CHEMICAL PROCESS UTILIZING CHEMOAUTOTROPHIC MICROORGANISMS FOR THE CHEMOSYTHETIC FIXATION OF CARBON DIOXIDE AND/OR OTHER INORGANIC CARBON SOURCES INTO ORGANIC COMPOUNDS, AND THE GENERATION OF ADDITIONAL USEFUL PRODUCTS - The invention described herein presents compositions and methods for a multistep biological and chemical process for the capture and conversion of carbon dioxide and/or other forms of inorganic carbon into organic chemicals including biofuels or other useful industrial, chemical, pharmaceutical, or biomass products. One or more process steps utilizes chemoautotrophic microorganisms to fix inorganic carbon into organic compounds through chemosynthesis. An additional feature described are process steps whereby electron donors used for the chemosynthetic fixation of carbon are generated by chemical or electrochemical means, or are produced from inorganic or waste sources. An additional feature described are process steps for the recovery of useful chemicals produced by the carbon dioxide capture and conversion process, both from chemosynthetic reaction steps, as well as from non-biological reaction steps. | 2013-03-28 |
20130078691 | Microorganisms Having Enhanced Resistance To Acetate And Related Compositions And Methods of Use - The present invention provides isolated or genetically modified strains of microorganisms that display enhanced resistance to acetate as a result of increased expression of a sodium proton antiporter. The present invention also provides methods for producing such microbial strains, as well as related promoter sequences and expression vectors. Further, the present invention provides methods of producing alcohol from biomass materials by using microorganisms with enhanced resistance to acetate. | 2013-03-28 |
20130078692 | KETOREDUCTASE POLYPEPTIDES FOR THE REDUCTION OF ACETOPHENONES - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds. | 2013-03-28 |
20130078693 | PROCESSES FOR STARTING UP DEEP TANK ANAEROBIC FERMENTATION REACTORS FOR MAKING OXYGENATED ORGANIC COMPOUND FROM CARBON MONOXIDE AND HYDROGEN - Processes are provided for starting up of anaerobic, deep tank fermentation systems used in the anaerobic bioconversion of hydrogen and carbon monoxide in a gaseous substrate stream to oxygenated organic compounds such as ethanol. In the processes injectors using a motive liquid are used to introduce gas substrate into the deep tank fermentation reactor where at least one of:
| 2013-03-28 |
20130078694 | PANTOTHENIC ACID BIOSYNTHESIS IN ZYMOMONAS - is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. | 2013-03-28 |
20130078695 | Pretreatment Method for Producing Water-Soluble Sugars From Lignocellulosic Material - The invention relates to manufacturing hydrolyzable cellulose and further, if desired, sugars from lignocellulosic material by means of formic and performic acid treatment. | 2013-03-28 |
20130078696 | PROCESSING BIOMASS - Carbon-containing materials, such as biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) or coal are processed to produce useful products, such as fuels. For example, systems are described that can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy materials, to produce ethanol. | 2013-03-28 |
20130078697 | FERMENTATION SYSTEM AND FERMENTATION METHOD USING SACCHARIDE SOLUTION - An alcohol production system that produces alcohol by alcoholic fermentation using a saccharide solution, including an alcoholic fermentation vessel in which the saccharide solution is fermented by adding yeast to produce alcohol, which is an organic feedstock, and a biomass-hydrothermally-treated-product adding means that adds a biomass hydrothermally-treated product obtained by hydrothermally treating a biomass feedstock to the alcoholic fermentation vessel. The alcohol production system can improve alcoholic fermentation efficiency and realize cost reduction without adding only a mineral salt from outside. | 2013-03-28 |
20130078698 | PROCESS FOR FRACTIONATION OF BIOMASS - A process of fractionation of biomass using aqueous ammonia for fractionation of biomass into lignin, cellulose and/or hemicellulose is provided herein. The process disclosed in the present invention is recovers lignin, cellulose and hemicellulose in more than 90% purity. The present invention also provides process of saccharification and fermentation of biomass using aqueous ammonia for production of soluble sugars, alcohols, acids, phenols and other desired products, or derivatives thereof. The process disclosed in the present invention is robust, cost effective and scalable. | 2013-03-28 |
20130078699 | COMPOSITIONS AND METHODS FOR PRODUCING ISOPRENE - The invention features methods for producing isoprene from cultured cells. The invention also provides compositions that include these cultured cells. | 2013-03-28 |
20130078700 | Method and system for the gas-tight process control of percolators in a biogas method having two or more stages - The invention relates to a method and a system for obtaining biogas in two or more stages in a hydrolysis and a methane stage, wherein the hydrolysis of solid biogenic materials is performed in at least two percolators operated at offset times. Liquid hydrolyzate and CO | 2013-03-28 |
20130078701 | DEVICE COMPRISING A CONDUCTIVE SURFACE AND A CONDUCTIVE POLYMER FOR ADHESION OF CELLS AND TISSUE - The present disclosure relates to a device comprising a conductive substrate surface ( | 2013-03-28 |
20130078702 | DEVICE FOR VIRAL INACTIVATION OF LIQUID MEDIA - An apparatus ( | 2013-03-28 |
20130078703 | METHOD OF REGENERATING AN ENZYMATI CATALYST - A method of regenerating an enzymatic catalyst arranged in a reactor includes a mineral support based on metal oxide and at least one enzyme, wherein it contains at least one step of detachment of the spent enzymes by solvation by scavenging of the catalyst using at least one ionic surfactant, and at least one step of re-attachment of active enzymes by scavenging of the purified support with at least one solution of active enzymes, the two steps being performed in situ within the reactor. | 2013-03-28 |
20130078704 | Processing Chemicals - Methods of processing chemicals change their structure, and in particular increase their solubility and/or rate of dissolution, for intermediates and products made from the structurally changed materials. Many of the methods provide materials that can be more readily utilized in reactions or other processes to produce useful intermediates and products, e.g., energy, fuels, foods or materials. Chemicals that are treated using the processes described herein can be used to form highly concentrated solutions. Treatment can change the functionality of the chemical, and thus the polarity of the chemical, which may render the treated chemical soluble in solvents in which the untreated chemical is insoluble or only sparingly or partially soluble. Methods may in some cases increase the solubility of the chemical in water or aqueous media. The chemical may be, for example, a solid, liquid, or gel, or mixtures thereof. | 2013-03-28 |
20130078705 | PROTEASE FOR TREATING NAIL ABNORMALITIES - A protease for treating nail abnormalities is a type of protease. Since nails are mostly composed of keratin protein, the optimum protease for decomposing the main component (keratin) of the nail is keratinase or serine protease which is functionally similar to keratinase. The serine protease include trypsin, chymotrypsin, elastase, subtilisin, etc, these enzymes can be used to treat pathologically or mechanically damaged nail tissue to thin or remove keratin which is the key component of the nail, thus facilitating drug delivery in later treatment. | 2013-03-28 |
20130078706 | METHOD OF TRANSFORMING CELLS - Use of an isolated | 2013-03-28 |
20130078707 | NOVEL RADIORESISTANT ALGA OF THE COCCOMYXA GENUS - The invention relates to novel algae of the | 2013-03-28 |
20130078708 | CONTINUOUS OR SEMI-CONTINUOUS FLOW PHOTOBIOREACTOR AND METHOD OF USE - The present invention is directed to a photobioreactor for continuous or semi-continuous flow culturing photosynthesizing biomass and related method. In particular, the invention relates to a photobioreactor for continuous or semi-continuous flow culturing photosynthesizing algal biomass and related method. The photobioreactor comprises a gas feeding portion ( | 2013-03-28 |
20130078709 | Nucleic Acids Useful in the Manufacture of Oil - Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae. | 2013-03-28 |
20130078710 | SYSTEMS AND METHODS FOR EX-VIVO ORGAN CARE AND FOR USING LACTATE AS AN INDICATION OF DONOR ORGAN STATUS - The invention provides, in various embodiments, systems, devices and methods relating to ex-vivo organ care. In certain embodiments, the invention relates to maintaining an organ ex-vivo at near-physiologic conditions. The present application describes a method for using lactate measurement in the arterial and the venous blood lines of the Organ Care System Heart perfusion device to evaluate the: 1) The overall perfusion status of an isolated heart and 2) The metabolic status of an isolated heart and 3) the overall vascular patency of an isolated donor heart. This aspect of the present invention uses the property of myocardial cell's unique ability to produce/generate lactate when they are starved for oxygen and metabolize/utilize lactate for energy production when they are well perfused with oxygen. | 2013-03-28 |
20130078711 | SYSTEMS AND METHODS FOR PROVIDING MICROFLUIDIC DEVICES - A microfluidic valve system is disclosed that includes a matrix, a hydrophilic acceptor region a hydrophilic transfer region, and a hydrophobic gap between the acceptor region and the transfer region. | 2013-03-28 |
20130078712 | Nucleic Acid Amplifier and Nucleic Acid Inspection Device Employing the Same - A nucleic acid amplifier comprises a holder | 2013-03-28 |
20130078713 | Thermal Cycler For PCR - An assembly for cycling vials of reaction mixtures through a series of temperature excursions is provided. The assembly can include a sample block for receiving the vials, a plurality of thermoelectric devices, a heat sink, and a clamping mechanism positioned to clamp the thermoelectric devices between the sample block and heatsink. The assembly can also include a thermal connector having a first end and a second end, the first end in close contact with the sample block and the second end in close contact with the heatsink to provide a thermal path between the sample block and the heatsink, the thermal connector being positioned to reduce thermal gradients across the sample block. The assembly can further include means for connecting the assembly to a computing apparatus for controlling the temperature excursions of the assembly. | 2013-03-28 |
20130078714 | CULTURE APPARATUS PROVIDED WITH HEAT PIPE - A culture apparatus includes a heat insulating box main body having an inner box; a culture vessel; a duct and a circulation blower forcing convection of a gas in the culture vessel; a humidifying pan disposed on the bottom of the culture vessel and positioned inside the duct; a heat pipe having a heat insulating section, a heat input section disposed at one end of the heat insulating section and a heat dissipation section disposed at the other end of the heat insulating section. The heat pipe is attached to the culture apparatus with the heat dissipation section being disposed outside the culture apparatus, the heat insulating section passing through the heat insulating box main body and the inner box, and the heat input section being disposed in a gas passage in the duct. | 2013-03-28 |
20130078715 | Anti-MicroRNA Oligonucleotide Molecules - The invention relates to isolated anti-microRNA molecules. In another embodiment, the invention relates to an isolated microRNA molecule. In yet another embodiment, the invention provides a method for inhibiting microRNP activity in a cell. | 2013-03-28 |
20130078716 | VCP-Based Vectors for Algal Cell Transformation - Provided herein are exemplary vectors for transforming algal cells. In exemplary embodiments, the vector comprises a Violaxanthin-chlorophyll a binding protein (Vcp) promoter driving expression of an antibiotic resistance gene in an algal cell. Embodiments of the invention may be used to introduce a gene (or genes) into the alga | 2013-03-28 |
20130078717 | BINDING MEMBERS-513 - This invention relates to binding members, especially antibody molecules, specific for interleukin 1 receptor 1 (IL-1R1). For example, isolated binding members specific for IL-1R1 which competes with IL-1 and IL-1Ra for binding to IL-1R1 and binds Il-1R1 with a K | 2013-03-28 |
20130078718 | CONVERSION OF VASCULAR ENDOTHELIAL CELLS INTO MULTIPOTENT STEM-LIKE CELLS - Disclosed herein is a method of producing multipotent cells, comprising, activating ALK2 of isolated endothelial cells in a serum starved environment, to thereby produce isolated multipotent cells. Activation can be following a threshold period of serum starvation. Activating ALK2 is by contacting the isolated endothelial cells with TGFβ-2 and/or BMP4. The isolated endothelial cells may be human, such as primary vascular, primary microvascular endothelial cells, primary human umbilical vein endothelial cells (HUVEC) or primary human cutaneous microvascular endothelial cells (HCMEC). The activation of ALK2 significantly decreases expression of VE-cadherein of the cells and/or significantly increases expression of one or more of STRO-1, FSP-1, α-SMA, N-cadherin, fibronectin (FN1), Snail (SNAI1), Slug (SNAI2), ZEB-1, SIP-1, LEF-1, Twist, CD10, CD13, CD44, CD73, CD90, CD120A, and CD124. The multipotent cells may further be used to generate other cell types such as osteoblast-like cells, chondrocyte-like cells, adipocyte-like cells, neural-like cells, and myocyte-like cells, by incubating the isolated multipotent cells in the appropriate culture conditions for a period sufficient to induce differentiation. The induced cells express TIE-2. | 2013-03-28 |
20130078719 | NOVEL SHRNA MOLECULES AND METHODS OF USE THEREOF - The present invention relates to certain novel shRNA molecules and methods of use thereof. According to certain embodiments of the present invention, methods for reducing the expression level of a target gene are provided. Such methods generally comprise providing a cell with one or more precursor nucleic acid sequences that encode two or more RNA molecules. A first RNA molecule comprises a double stranded sequence, which includes a guide strand sequence that is complementary to a portion of an mRNA transcript encoded by the target gene. In addition, a second RNA molecule comprises a second double stranded sequence, which includes a second guide strand sequence that is partially complementary to a portion of the mRNA transcript encoded by the target gene. Preferably, the second guide strand sequence comprises one or more bases that are mismatched with a nucleic acid sequence of the mRNA transcript encoded by the target gene. | 2013-03-28 |
20130078720 | METHOD FOR INDUCING PLURIPOTENCY IN HUMAN SOMATIC CELLS WITH PRDM14 OR NFRKB - Methods of inducing pluripotency in human somatic cells and methods of maintaining pluripotency in human embryonic stem cells (hESCs) are provided, as well as cells and uses of employing such cells. The methods comprise culturing cells in the presence of (i) OCT4 and SOX2; (ii) at least one of KLF4 and c-MYC; and at least one of PRDM14 and NFRKB. | 2013-03-28 |
20130078721 | Cell Culture Medium for the Growth and Differentiation of Cells of the Hematopoietic Lineage - The present invention relates to a cell culture medium for the growth and/or differentiation of cells of the hematopoietic lineage, comprising: —insulin at a concentration of from 1 to 50 μg/ml; —transferrin at a concentration of from 100 μg/ml to 2000 μg/ml; and—plasma or serum at a concentration of from 1% to 30%. | 2013-03-28 |
20130078722 | METHODS OF MULTIPLYING CONIFER EMBRYOGENIC TISSUE - The invention provides methods for multiplying conifer embryogenic tissue. The methods of the invention comprise the steps of: (a) culturing conifer embryogenic tissue in or on a solid multiplication medium comprising one or more growth hormones; and (b) culturing the conifer embryogenic tissue multiplied in step (a) in or on a liquid multiplication medium comprising one or more growth hormones, wherein the initial concentration of growth hormones in the solid multiplication medium of step (a) is greater than the initial concentration of growth hormones in the liquid multiplication medium of step (b). | 2013-03-28 |
20130078723 | Genetic Material Manipulation Techniques and Products Thereof - The presently claimed invention applies to a genetic material processing and manipulation method and related product. The claimed invention relates to a method for changing the inherited characteristics of a cell through micro-beam chromosome modification. In one preferred embodiment, improvements to ‘genomic surgery’ are applied to modify source cell genetic material ( | 2013-03-28 |
20130078724 | Control Solution For Use In An Electrochemical System - A method of distinguishing a control solution from a sample in an electrochemical test sensor is performed. The method includes adding a control marker to the control solution. The control solution includes the control marker and analyte. The test sensor includes working and counter electrodes, and a reagent. A potential is applied to the test sensor to oxidize the control marker and the analyte. The resulting electrical current is measured. A potential is applied to the test sensor lower than the other potential in which the potential is sufficient to oxidize the analyte and not the control marker. The resulting electrical current is measured. Determining whether a control solution or a sample is present based on the measured electrical currents. To increase the measured current, a salt may be added to the control solution in an amount sufficient to increase the electrical current by at least 5% as compared to a control solution in the absence of a salt. | 2013-03-28 |
20130078725 | ENGINE CATALYST DIAGNOSTICS - Embodiments for predicting catalyst function are disclosed. One example embodiment includes applying a set of parameter readings for a given sample to a support vector machine to generate a classification output, recording a plurality of classification outputs for a plurality of successive samples over a first duration, and indicating catalyst degradation if a threshold percentage of the classification outputs indicates degraded catalyst performance. In this way, catalyst degradation may be indicated using a simplified model that does not require extensive calibration. | 2013-03-28 |
20130078726 | Method of Recovering Heavy Metal and Reagent for Recovery of Heavy Metal for Use in the Same - The present invention provides a method of recovering a heavy metal by which the variation in heavy metal recovery rate among samples can be suppressed. A mixture of a sample and a chelating agent capable of chelating with a heavy metal is prepared. A complex between a heavy metal being in the sample and the chelating agent is formed in the presence of a masking agent for a thiol group in the mixture. The heavy metal in the sample is recovered by recovering the complex. By this method, a heavy metal can be recovered with suppressing the variation in the recovery rate among samples. The chelating agent preferably is 1,5-diphenyl-3-thiocarbazone (dithizone). As the masking agent, N-ethylmaleimide, iodoacetamide, iodoacetic acid, or the like can be used. | 2013-03-28 |
20130078727 | METHODS AND COMPOSITIONS FOR NMR SPECTROSCOPIC ANALYSIS USING ISOTOPIC LABELING SCHEMES - Provided herein are methods and compositions for efficient accumulation of structural information (e.g., three dimensional structural information) for amino acid sequences. | 2013-03-28 |
20130078728 | Novel Isobaric Tandem Mass Tags for Quantitative Proteomics and Peptidomics - Compositions and methods of tagging peptides and other molecules using novel isobaric tandem mass tagging reagents, including novel N,N-dimethylated amino acid 8-plex and 16-plex isobaric tandem mass tagging reagents. The tagging reagents comprise: a) a reporter group having at least one atom that is optionally isotopically labeled; b) a balancing group, also having at least one atom that is optionally isotopically labeled, and c) an amine reactive group. The tagging reagents disclosed herein serve as attractive alternatives for isobaric tag for relative and absolute quantitation (iTRAQ) and tandem mass tags (TMTs) due to their synthetic simplicity, labeling efficiency and improved fragmentation efficiency. | 2013-03-28 |
20130078729 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - A reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, an in vitro method for the detection of a vitamin D compound in which the vitamin D compound is released from vitamin D-binding protein by the use of this reagent composition and the reagent mixture obtained in this manner. The use of the disclosed reagent composition to release vitamin D compounds as well as a kit for detecting a vitamin D compound which contains the reagent composition for releasing vitamin D compounds in addition to common detecting reagents. | 2013-03-28 |
20130078730 | METHOD FOR MONITORING AND CONTROL OF A WASTEWATER PROCESS STREAM - The invention is directed towards methods, compositions, and apparatus for accurately detecting the presence and amounts of contaminants in wastewater. The method comprises the steps of adding to a volume of wastewater at least one tracer molecule, observing the tracer for indications of particular contaminants, conducting at least one second form of contamination detection, and interrelating the two measured properties to identify the specific composition of the contamination. Using a tracer molecule allows for the detection of otherwise hard to detect oils and grease. Use of the second method however compensates for tracer interfering contaminants and allows for more accurate readings. The invention includes feeding of functional chemicals in response to the detections and conducting the detections online and continuously. | 2013-03-28 |
20130078731 | CHROMOPHORES FOR THE DETECTION OF VOLATILE ORGANIC COMPOUNDS - Aromatic diimide chromophores and methods for using the chromophores for the detection of volatile organic compounds are described. The chromophores are able to reversibly change colors in the presence or absence of volatile organic compounds. | 2013-03-28 |
20130078732 | METHODS FOR DIAGNOSING IMPENDING JOINT FAILURE - The invention provides methods for diagnosing impending joint failure in an animal by measuring the concentration of phenylalanine in a body fluid; measuring the concentration of one or more of tyrosine, alanine, valine, and glutamine in the body fluid; determining the ratio of phenylalanine to one or more of tyrosine, alanine, valine, and glutamine; and diagnosing impending joint failure by comparing the ratio to ratios predicative of impending joint failure. | 2013-03-28 |
20130078733 | SYSTEMS AND METHODS FOR FLUID HANDLING - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 2013-03-28 |
20130078734 | MICROSCOPE SLIDE COVER WITH INTEGRATED RESERVOIR - A cover for a substrate including: a body defining a cavity, for positioning over the substrate to form a reaction chamber; and a projection extending from the body to define a fluid reservoir, when the cover is fitted to the substrate, the fluid reservoir being in fluid communication with the cavity. | 2013-03-28 |
20130078735 | METHOD FOR PREPARING A SAMPLE FOR CHROMATOGRAPHIC SEPARATION PROCESSES AND SYSTEMS FOR CARRYING OUT A SAMPLE PREPARATION - The invention relates to a method for preparing a sample for chromatographic separation processes, in which a sample vessel ( | 2013-03-28 |
20130078736 | SYSTEM AND APPARATUS FOR REACTIONS - This disclosure provides systems, apparatuses, and methods for liquid transfer and performing reactions. In one aspect, a system includes a liquid transfer device having a housing having a pipette tip and a plunger assembly; and a reaction chamber, wherein the housing of the liquid transfer device is configured to sealably engage with the reaction chamber. In another aspect, a liquid transfer device including a housing having a pipette tip; and a plunger assembly disposed within the housing and the pipette tip, wherein a portion of the plunger assembly is configured to engage a fluid reservoir such that the plunger assembly remains stationary relative to the fluid reservoir and the housing moves relative to the plunger assembly. | 2013-03-28 |
20130078737 | THYROXINE IMMUNOASSAY USING FLUORESCENT PARTICLES - Provided are a base plate and a method for thyroxine immunoassay, which are capable of decreasing the signal change rate caused by temperature change in a high-sensitivity immunoassay method for thyroxine. A base plate for thyroxine immunoassay which has a conjugate of thyroxine or a derivative thereof and albumin immobilized thereon, and in which the ratio of the molecule number of thyroxine or a derivative thereof to the molecule number of albumin in the immobilized conjugate, is disclosed. | 2013-03-28 |
20130078738 | METHOD FOR MEASURING SUBSTANCE TO BE MEASURED USING FLUORESCENT PARTICLES, TEST SUBSANCE MEASUREMENT CHIP, AND TEST SUBSANCE MEASUREMENT KIT - A method for measuring a test substance including (1) reacting fluorescent particles and a test substance by bringing the test substance and the fluorescent particles into contact with a test area and a control area present on a substrate, (2) removing the unreacted fluorescent particles, (3) measuring the fluorescence of the fluorescent particles of the test area and the control area, and (4) correcting a fluorescence signal value in the test area using a fluorescence signal value in the control area, wherein the fluorescent particles are binding substance-labeling fluorescent particles in which one or more of a first binding substance which can bind to the test substance, and a third binding substance which can bind to a second binding substance and which does not bind to the test substance are bound, and the second binding substance which can bind to the first binding substance is immobilized on the control area. | 2013-03-28 |
20130078739 | CORTISOL IMMUNOASSAY USING FLUORESCENT PARTICLES - Provided are a base plate and a method for cortisol immunoassay, which enable immunoassay of cortisol with high sensitivity particularly in a clinically significant cortisol concentration range (that is, 1 μg/dL to 30 μg/dL). A base plate for cortisol immunoassay which has a cortisol albumin conjugate having a cortisol/albumin ratio of from 12 to 20 immobilized thereon is disclosed. | 2013-03-28 |
20130078740 | PREPARATION OF MICROFLUIDIC DEVICE ON METAL NANOPARTICLE COATED SURFACE, AND USE THEREOF FOR NUCLEIC ACID DETECTION - The invention relates to a microfluidic device that utilizes nucleic acid-based detection and a detection system containing the same, as well as a process for preparing the micro fluidic device and for using the same to detect the presence of a target nucleic acid molecule in a sample. | 2013-03-28 |
20130078741 | IGA-BINDING PEPTIDE AND PURIFICATION OF IGA USING THE SAME - This invention relates to: a peptide which comprises an amino acid sequence consisting of 12 to 18 amino acid residues represented by (X | 2013-03-28 |