14th week of 2014 patent applcation highlights part 45 |
Patent application number | Title | Published |
20140094548 | Polyamide moulding compounds and use thereof in the production of moulded articles - The present invention relates to polyamide moulding compounds, pigmented black, which include nigrosin and at least one nucleation agent, carbon black being ruled out. The present invention likewise relates to a method for producing moulded articles from the mentioned polyamide moulding compounds and also the corresponding moulded articles. The polyamide moulding compounds are used in the production of components with increased temperature requirements, e.g. in the automobile sector. | 2014-04-03 |
20140094549 | POLYCARBONATE RESIN COMPOSITION AND FORMED PRODUCT THEREOF - In a polycarbonate resin composition containing a polycarbonate resin and a polycarbosilane compound, the use of the polycarbosilane compound modifies the surface properties of the polycarbonate resin composition without adversely affecting the intrinsic characteristics of the polycarbonate resin, such as transparency, heat resistance, and mechanical properties, e.g., impact resistance. A polycarbonate resin composition containing 100 parts by mass of a polycarbonate resin, 0.001 to 1 part by mass of a metal salt compound, and 0.005 to 5 parts by mass of a polycarbosilane compound has significantly improved flame resistance and high transparency and causes markedly reduced outgassing and mold fouling, without losing impact resistance and heat resistance. | 2014-04-03 |
20140094550 | RELEASE POLYCARBONATE COMPOSITIONS - The present application relates to a thermoplastic composition, comprising: a polycarbonate polymer; 0.05 to 0.2 weight percent of a triacylglyceride release agent; and 0.25 to 0.55 weight percent of a tetrastearate second release agent. The total amount of the triacylglyceride release agent and the second release agent is less than or equal to 0.6 weight percent and the weight percent values are based on the total weight of the composition. | 2014-04-03 |
20140094551 | COMPOSITIONS INCORPORATING DIELECTRIC ADDITIVES FOR PARTICLE FORMATION, AND METHODS OF PARTICLE FORMATION USING SAME - A method of forming particles that includes performing a strong force attenuation of a mixture to form pre-particles. The mixture including a base compound and a dielectric additive having an elevated dielectric constant dispersed therein. The pre-particles are then dielectrically spun in an electrostatic field to further attenuate the pre-particles and form the particles. | 2014-04-03 |
20140094552 | ENZYME CURABLE ALKYD COMPOSITION - The present invention relates to a coatings composition comprising an alkyd, a pigment, a rheology modifier, a radical producing oxidoreductase, and one or more additives, wherein the alkyd contains at least one C | 2014-04-03 |
20140094553 | CURABLE COMPOSITION - The present invention provides a curable composition useful as a contact adhesive which has a high rate of initial tack development, high tack strength, and long retention time of the developed tack. The curable composition includes an organic polymer (Q) containing a reactive silyl group, and a linear organic polymer (P) having a number average molecular weight larger than that of the polymer (Q) and having a reactive silyl group containing three hydrolyzable groups at only one terminal. The organic polymer (P) and the organic polymer (Q) are mixed at a mixing ratio (P):(Q), in terms of parts by weight, of 60:40 to 5:95. | 2014-04-03 |
20140094554 | ROOM TEMPERATURE AND HUMIDITY THICKENING THERMO-CONDUCTIVE SILICON GREASE COMPOSITION - Provided is a room temperature and humidity thickening thermo-conductive silicone grease composition with high shape retention characteristics and good workability despite a low viscosity in an initial phase. Essential components of the room temperature and humidity thickening thermo-conductive silicone grease composition of the present invention are: (A) organopolysiloxane with a viscosity of between 0.1 Pa·s and 1,000 Pa·s at 25° C. with both ends being blocked by a hydroxyl group; (B) organopolysiloxane represented by general equation (1) | 2014-04-03 |
20140094555 | CARBON-FIBER-REINFORCED PLASTIC AND PROCESS FOR PRODUCING SAME - A carbon-fiber-reinforced plastic prepared by impregnating a matrix resin into a sheet-like base material includes discontinuous carbon fibers, wherein a content ratio of carbon fibers having lengths of 10 mm or longer in the base material is 60 wt % or more relative to a total amount of the carbon fibers, and an average value of orientation degrees of carbon fibers contained in the base material is 2-10. | 2014-04-03 |
20140094556 | THERMAL STABILIZER-FREE THERMOPLASTIC RESIN COMPOSITION AND METHOD OF PREPARING THE SAME - Disclosed are a thermal stabilizer-free thermoplastic resin composition and a method of preparing the same. The thermal stabilizer-free thermoplastic resin composition has superior impact resistance, falling ball impact resistance and gloss without using a separate thermal stabilizer. Particularly, the thermal stabilizer-free thermoplastic resin composition improves production efficiency when applied to a squeezing dehydrator because the thermoplastic resin composition is prepared without using a drying process. | 2014-04-03 |
20140094557 | Expandable TFE Copolymers, Method of Making, and Porous, Expanded Articles Thereof - A true tetrafluoroethylene (TFE) copolymer of the fine powder type is provided, wherein the copolymer contains polymerized comonomer units of at least one comonomer other than TFE in concentrations of at least or exceeding 1.0 weight percent, and which can exceed 5.0 weight percent, wherein the copolymer is expandable, that is, the copolymer may be expanded to produce strong, useful, expanded TFE copolymeric articles having a microstructure of nodes interconnected by fibrils. Articles made from the expandable copolymer may include tapes, membranes, films, fibers, and are suitable in a variety of end applications, including medical devices. | 2014-04-03 |
20140094558 | Low Energy, Cold Process Formulation Aid - Provided are cold process formulation aids, methods for their manufacture, and personal care products made using them. The cold processing aids include a wax and a polymer having a backbone and a plurality of pendant groups thereon that are pendant ionic or ionizable groups, or pendant groups having at least one permanent dipole that includes an alcohol, thiol, ester, amide, imide, imine, or nitrile moiety. The backbone can be an aliphatic backbone, a polysaccharide backbone, a siloxane backbone, or a polyamide backbone. Also provided is a method of making personal care products using the cold processing aid. | 2014-04-03 |
20140094559 | INK JET INK COMPRISING ENCAPSULATED PIGMENT DISPERSIONS WITH MINIMAL FREE POLYMER - The present disclosure provides an inkjet ink comprising an aqueous vehicle and an encapsulated pigment dispersion. A process for encapsulating pigment dispersions is provided where a pigment is dispersed with a polymeric dispersant in an aqueous solvent system. The free polymer dispersant in the pigment dispersion is limited to less than 0.12 grams per gram of pigment. This dispersed pigment is then encapsulated by adding acrylate monomers and optionally acrylic and vinyl monomers and polymerizing. In the encapsulated pigment dispersion the weight ratio of final free polymer to polymer found to the final encapsulated pigment is less than 0.9. The free polymer dispersant is measured by a centrifugation method and the final free polymer is measured by a density gradient centrifugation method. Such encapsulated pigment dispersions may be used in inkjet inks and are stable to heat, aging test conditions, and solvent challenges. Prints from these inks have better durability. | 2014-04-03 |
20140094560 | CURABLE FORMALDEHYDE FREE COMPOSITIONS AS BINDERS HAVING SOLVENT RESISTANCE - The present invention provides aqueous binder compositions comprising one or more polyol and a multistage copolymer, preferably, an all acrylic and allylic or all acrylic copolymer, having as the outermost stage a polymerized acid functional aqueous solution polymer and as the one or more remaining stage(s) a vinyl emulsion polymer, wherein the emulsion polymer stage(s) in the multistage copolymer comprises 5 wt. % or less of hydrophilic monomer, based on the total weight of monomers used to make the emulsion polymer stage(s). The multistage copolymer enables incorporation of a much higher amount of hydrophilic monomer into a polymeric binder without the attendant handling or viscosity problems. Also provided are methods of using the aqueous binder compositions comprising pultruding two or more non-woven fibers or a fiber roving with the aqueous binder composition, and drying, Articles comprising the bound fiber(s) are provided. | 2014-04-03 |
20140094561 | PROCESS FOR PRODUCING COMPOSITE MATERIALS - The present invention relates to a process for producing a composite material composed of at least one inorganic or organometallic phase and one organic polymer phase with aromatic or heteroaromatic structural units, wherein homo- or copolymerization of the monomers of the formula I is performed in the presence of a base selected from organic nitrogen bases and inorganic or organic oxo bases and fluoride salts. | 2014-04-03 |
20140094562 | MODIFIED POLYPHENOL BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME - Modified polyphenol binder compositions and methods for making and using same are provided. In at least one specific embodiment, the binder composition can include at least one unsaturated monomer and at least one polyphenolic compound. The polyphenolic compound can include a lignin, a tannin, a novolac resin, a modified phenol formaldehyde resin, bis-phenol A, humic acid, or any mixture thereof. | 2014-04-03 |
20140094563 | PROCESS FOR MAKING NON-HALOGENATED FLAME RETARDANT POLYMERIC COMPOSITES WITH NANOSTRUCTURES - The present invention generally relates to a process for making non-halogenated flame retardant polymeric composites with superabsorbent polymer coated nanoparticles to provide excellent flame retardant property, low toxicity and high loading efficiency. The flame retardant polymeric composites can be used as flame retarding foams, insulation sheeting materials or other composite materials. | 2014-04-03 |
20140094564 | ARTICLE PREPARED FROM CLEAN FLUOROPOLYMERS - There is provided an article prepared from a fluoroelastomer, the fluoroelastomer being derived from an emulsion, the emulsion comprising a fluorinated emulsifier represented by the formula F—(CF | 2014-04-03 |
20140094565 | METHOD FOR PRODUCING SILOXANE OLIGOMERS - [Subject] The object of the present invention is to provide a method for producing siloxane oligomers which contain a small amount of ring form and have a high molecular weight. | 2014-04-03 |
20140094566 | Pavement Marking Composition System - A composition system includes a first portion having an isocyanate monomer and an acrylate monomer and a second portion includes a secondary amine monomer having at least two carbon atoms bonded to a nitrogen atom of the secondary amine monomer and at least one of the carbon atoms has two carbon atoms bonded to the carbon atom. The second portion includes a thermal acrylate polymerization initiator. The composition system can be utilized as pavement marking. | 2014-04-03 |
20140094567 | Diketopiperazine Forming Dipeptidyl Linker - The invention relates to a method for homogeneous solution phase peptide synthesis (HSPPS) of a N-terminal peptide fragment PEP-N and a C-terminal peptide fragment C-PEP, with C-PEP carrying a specific diketopiperazine (DKP) comprising C-terminal protecting group, which contains a handle group HG, with HG being connected to the C-terminus of the peptide fragment; thereby this specific DKP comprising C-terminal protecting group can be selectively cleaved from the peptide as a conventionally used C-terminal protecting group. By the use of this DKP and HG comprising C-terminal protecting group, certain process steps in convergent peptide synthesis based on a combination of HSPPS and solid phase peptide synthesis (SPPS) can be avoided. The invention relates further to a method for the preparation of such specifically protected fragment C-PEP by SPPS by using a linker comprising a specific dipeptide and HG for connecting the growing peptide chain to the resin, which linker forms said DKP group, when the peptide fragment C-PEP is cleaved from the supporting resin; and further to the intermediates of the preparation method. | 2014-04-03 |
20140094568 | OUTER LAYER HAVING ENTANGLEMENT OF HYDROPHOBIC POLYMER HOST BLENDED WITH A MALEATED HYDROPHOBIC POLYMER CO-HOST, AND HYDROPHILIC POLYMER GUEST - The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a hydrophilic guest, including in one embodiment the steps of: intermingling cloaked hydrophilic guest complexes with the hydrophobic host; crosslinking molecules of the guest with the guest; and performing a hydrolysis reaction. | 2014-04-03 |
20140094569 | SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF - The present invention provides a method for preparing a sample characterized by binding a substance A containing a hydrazide group to a sugar chain and/or a sugar derivative via hydrazone formation between the hydrazide group of the substance A and the reducing end of the sugar chain and/or the sugar derivative thereby to enable the separation and purification of the sugar chain and/or the sugar derivative for an analytical sample from a biological sample containing the sugar chain and/or the sugar derivative by a simple operation. | 2014-04-03 |
20140094570 | METHOD FOR PRODUCING A WATER-ABSORBENT RESIN - The present invention provides a water-absorbent resin produced by a reversed-phase suspension polymerization method, which contains a small amount of a petroleum hydrocarbon dispersion medium remaining therein used in reversed-phase suspension polymerization, and thus reducing an odor originating from the petroleum hydrocarbon dispersion medium, when the water-absorbent resin absorbs water, and also which is suitable for use in hygienic materials; an absorbent material and an absorbent article. More particularly, the present invention provides a water-absorbent resin obtained by subjecting an aqueous solution of a water-soluble ethylenically unsaturated monomer to reversed-phase suspension polymerization in a petroleum hydrocarbon dispersion medium in the presence of a surfactant, wherein the amount of the petroleum hydrocarbon dispersion medium remaining in the water-absorbent resin is 2,000 ppm or less; and an absorbent material and an absorbent article using the same. | 2014-04-03 |
20140094571 | POLYURETHANE ON THE BASIS OF SOFT THERMOPLASTIC POLYURETHANE - The invention relates to polyurethanes based on a thermoplastic polyurethane and an isocyanate concentrate having a functionality greater than 2 and less than 10 added to the thermoplastic polyurethane, wherein the hard phase content of the thermoplastic polyurethane is in the range from 0% to 5% and the isocyanate concentrate is added in an amount of at least 2% by weight based on the polyurethane PU-1. | 2014-04-03 |
20140094572 | MANUFACTURING METHODS FOR THE PRODUCTION OF CARBON MATERIALS - The present application is generally directed to activated carbon materials and methods for making the same. The disclosed methods comprise rapidly freezing synthetically prepared polymer gel particles. The methods further comprise drying, pyrolyzing, and activating steps to obtain an activated carbon material of high porosity. The disclosed methods represent viable manufacturing processes for the preparation of activated carbon materials. | 2014-04-03 |
20140094573 | Process for producing polymers by means of emulsion or suspension polymerization in a jet loop reactor - A process for preparing a polymer in the form of an aqueous dispersion or a water-redispersible powder includes free-radically initiated heterophase polymerization of one or more ethylenically unsaturated monomers and optionally subsequent drying of the polymer dispersions obtained, wherein the polymerization is performed in a jet loop reactor. | 2014-04-03 |
20140094574 | POLYOLEFIN AND PREPARATION METHOD THEREOF - A polyolefin has 1) a density in the range of 0.93 to 0.97 g/cm | 2014-04-03 |
20140094575 | Process for Monomer Recovery From a Polymerization Process - The present relates to a process for optimizing the recovery of unreacted monomers from a polymerization process, wherein said process comprises the steps of
| 2014-04-03 |
20140094576 | PRE-POLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS - A pre-polymerized catalyst component for the polymerization of olefins CH | 2014-04-03 |
20140094577 | Catalyst Compositions Containing Transition Metal Complexes With Thiolate Ligands - The present invention discloses catalyst compositions employing transition metal complexes with a thiolate ligand. Methods for making these transition metal complexes and for using such compounds in catalyst compositions for the polymerization of olefins also are provided. | 2014-04-03 |
20140094578 | POLYMERIZABLE COMPOSITIONS - A polymerizable composition that comprises a first component comprising a (meth)acrylate and an organic peroxide as an oxidizing agent and a second component comprising a (meth)acrylate and a cysteine as a reducing agent which has a partial structure represented by the following structural formula, the first component and/or the second component further comprising a polymerization promoter: | 2014-04-03 |
20140094579 | Fluorocarbon anti-shrinkage leveling agent for coating and ink - A fluorocarbon leveling agent (fluoride-containing surfactant) for coating and ink has the surface tension of the leveling agent of 21-24 dynes, the number-average molecular weight of 1500-4500, the weight-average molecular weight of 3000-15000, and the polydispersity of 1.5-2.8. The present invention can reduce the surface tension of the coating system and has strong anti-shrinkage capability and excellent long wave leveling. | 2014-04-03 |
20140094580 | HARDCOATS COMPRISING PERFLUOROPOLYETHER POLYMERS WITH POLY(ALKYLENE OXIDE) REPEAT UNITS - Presently described are articles, such as optical displays and protective films, comprising a (e.g. light transmissive) substrate having a surface layer comprising the reaction product of a mixture comprising a non-fluorinated binder precursor (e.g. of a hardcoat composition) and at least one polymerizable perfluoropolyether polymer. The resulting cured surface layer can advantageously exhibit low lint attraction in combination with low surface energy. Also described are one-step and two-step methods of synthesizing perfluoropolyether polymers having polymerizable ethylenically unsaturated groups. | 2014-04-03 |
20140094581 | CURABLE COMPOSITION AND POLYMER - An object of the invention is to provide a curable composition having a HALS skeleton and capable of producing polymers having excellent weather resistance and outer appearance. The present invention provides a curable composition including at least a monomer component that contains a monomer (A) represented by a certain formula and a monomer (B) polymerizable with the monomer (A). In the curable composition, the content of the monomer (A) is 0.01 to 35 mol % in the monomer component, and the content of the monomer (B) is 65 to 99.99 mol % in the monomer component. | 2014-04-03 |
20140094582 | ETHYLENE-ALPHA-OLEFIN COPOLYMER - The present invention relates to an ethylene-α-olefin copolymer satisfying the following requirements (A) to (E):
| 2014-04-03 |
20140094583 | ETHYLENE-BASED POLYMERS AND PROCESSES TO MAKE THE SAME - An ethylene-based polymer, which is a low density polyethylene (LDPE), obtained by free radical polymerization of ethylene, and wherein the LDPE has a GPC parameter “LSP” less than 1.60. | 2014-04-03 |
20140094584 | POLYDIORGANOSILOXANE POLYAMIDE COPOLYMERS HAVING ORGANIC SOFT SEGMENTS - Polydiorganosiloxane polyamide, block copolymers having organic soft segments and methods of making the copolymers are provided. | 2014-04-03 |
20140094585 | Polymers Containing Metathesized Natural Oil Derivatives - Polymers containing natural oil derivatives are generally disclosed. Methods of forming such polymers are also generally disclosed. In some embodiments, the polymer is a polyurethane. In some embodiments, the natural oil derivative is a cross-linking group that links two or more polymer chains together. | 2014-04-03 |
20140094586 | HLA-BINDING PEPTIDE, AND DNA FRAGMENT AND RECOMBINANT VECTOR CODING FOR SAID HLA-BINDING PEPTIDE - An HLA-binding peptide binding to a HLA-A type molecule, the HLA-binding peptide includes at least one type of amino acid sequence selected from the group consisting of SEQ ID NOS: 1 to 80, and consists of not less than 8 and not more than 11 amino acid residues. All of these amino acid sequences herein mentioned are the predicted amino acid sequences binding to a human HLA-A type molecule with the prediction program using the certain active learnig method. | 2014-04-03 |
20140094587 | FILAMENTOUS FUNGI HAVING AN ALTERED VISCOSITY PHENOTYPE - Described are compositions and methods relating to variant filamentous fungi having altered growth characteristics. Such variants are well-suited for growth in submerged cultures, e.g., for the large-scale production of enzymes and other proteins for commercial applications. | 2014-04-03 |
20140094588 | PROGNOSTIC AND THERAPEUTIC SIGNATURE FOR MALIGNANT MELANOMA - The present invention relates to a method of predicting the course of disease in a patient having a malignant melanoma, the method comprising determining in melanoma cells comprised in a sample obtained from said malignant melanoma the presence or amount of at least five biomarkers selected from the group comprising or consisting of MTAP, PTEN, Bax, Bcl-X, β-Catenin, CD20, Cox-2, CD49d and MLH1, wherein the absence or decreased amount of MTAP and β-Catenin and/or the presence or increased amount of PTEN, Bax, Bcl-X, CD20, Cox-2, CD49d and MLH1, is associated with a disadvantageous course of disease. | 2014-04-03 |
20140094589 | METHOD FOR PRODUCING WEB PROTEIN, A FUSED PROTEIN, RECOMBINANT DNA, AN EXPRESSION VECTOR, A HOST CELL AND STRAIN-PRODUCERS - The invention relates to the field of biotechnology and provides a method for producing recombinant proteins from the orb-weaving spider silk in yeast cells. This involves the construction of an expression vector which comprises a DNA sequence encoding a recombinant protein of the orb-weaving spider silk fused with a sequence encoding an ubiquitin-like protein occupying an N-terminal position with respect to the spider silk recombinant protein within the fused protein. The expression of a hybrid gene makes it possible to increase tens of times the production of recombinant spider silk protein, wherein the recombinant protein accumulates in the yeast cells in a water-insoluble fraction in the form of a processed protein free of a hybrid component. | 2014-04-03 |
20140094590 | CELL-ADHESIVE PROTEIN - It is an object of the present invention to provide a protein having high cellular adhesiveness that is useful as a cell adhesion support. The present invention provides a cell-adhesive protein comprising methionine, wherein at least a portion of the methionine residues is oxidized. | 2014-04-03 |
20140094591 | METHODS FOR PURIFICATION OF ALPHA-1-ANTITRYPSIN AND APOLIPOPROTEIN A-1 - This invention relates to protein separation and purification methods for both alpha-1-antitrypsin (AAT, also known as alpha-1 proteinase inhibitor, API, and A.sub.1-PI) and Apolipoprotein A-I (ApoA-1) from, for example, a fraction of human blood plasma. In certain embodiments, the invention provides methods for separating AAT from ApoA-1 at the initial stage of purification, so that the same starting material can be used as a source for both proteins. The methods further pertain to providing compositions of AAT and of ApoA-1 suitable for pharmaceutical use and are suitable for large-scale purification. | 2014-04-03 |
20140094592 | Recombinant Pokeweed Antiviral Proteins, Compositions and Methods Related Thereto - The present invention provides novel, modified pokeweed antiviral proteins, nucleic acids that encode the proteins, conjugates that incorporate the proteins, and methods to make and use the proteins. The present invention also provides methods to administer the conjugates to animals, for the purpose of directing toxin to particular cells. | 2014-04-03 |
20140094593 | Purification method for proteins, in particular antibodies, utilizing a wash solution comprising arginine at high pH for the affinity chromatography step - The invention provides a washing method for affinity chromatography in which a wash solution comprising arginine, or an arginine derivative, at pH greater than 8.0, is effective in removing impurities without the presence of a nonbuffering salt, while simultaneously increasing product concentration in the eluate and maintaining a high percent yield of recovered product. | 2014-04-03 |
20140094594 | Immunoaffinity Isolation of Modified Peptides From Complex Mixtures - The invention provides methods for isolating a modified peptide from a complex mixture of peptides, the method comprising the steps of: (a) obtaining a proteinaceous preparation from an organism, wherein the preparation comprises modified peptides from two or more different proteins; (b) contacting the preparation with at least one immobilized modification-specific antibody; and (c) isolating at least one modified peptide specifically bound by the immobilized modification-specific antibody in step (b). The method may further comprise the step of (d) characterizing the modified peptide isolated in step (c) by mass spectrometry (MS), tandem mass spectrometry (MS-MS), and/or MS | 2014-04-03 |
20140094595 | Protein Scaffolds for Antibody Mimics and Other Binding Proteins - Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands. | 2014-04-03 |
20140094596 | PROCESS FOR MANUFACTURING A COMPOSITE SORBENT MATERIAL FOR CHROMATOGRAPHICAL SEPARATION OF BIOPOLYMERS - The present invention relates to a sorbent material for separation and purification of biopolymers, particularly nucleic acids, having a solid support substantially modified with a copolymer coating comprising aromatic monomers and crosslinking compounds and unsaturated esters or ethers preferably attached to the support via a vinylchlorsilane. The use of these materials for separation of nucleic acids, particularly a one-step isolation of DNA from lysates of different biological sources, is an object of the invention as well as a chromatographic column or cartridge at least partially filled with the sorbent material of the invention, a membrane-like device comprising the sorbent material of the invention, and a kit comprising the sorbent material of the invention in bulk or packed in chromatographic devices as well as other devices necessary for performing sample preparations. | 2014-04-03 |
20140094597 | METHOD FOR ISOLATING NUCLEIC ACIDS COMPRISING THE USE OF ETHYLENE GLYCOL MULTIMERS - The present invention provides a method of isolating nucleic acid from a sample, said method comprising contacting said sample with a solid support, preferably magnetic beads, in the presence of an ethylene glycol multimer consisting of from 2 to 70 ethylene oxide monomers, preferably tetraethylene glycol, whereby soluble nucleic acid in said sample is bound to the surface of the support, and separating said support with bound nucleic acid from the sample. Kits for performance of the invention are also provided. | 2014-04-03 |
20140094598 | METHOD FOR THE PURIFICATION OF DECITABINE - A method of preparing purified decitabine comprises mixing crude decitabine with solvent, such as dimethylacetamide, to form a solution or suspension and forming the purified decitabine from the solution or suspension. The forming step comprises adding an anti-solvent, such as ethanol, to the solution or suspension. The forming step may further comprise after adding ethanol to provide a mixture of dimethylacetamide and ethanol: cooling the mixture; isolating the solid decitabine present in the cooled mixture; and evaporating residual dimethylacetamide and ethanol from the solid decitabine to provide the purified decitabine. The mixture of dimethylacetamide and ethanol may be heated. The purification method preferably results in decitabine having a ratio of the β-anomer of decitabine to the α-anomer of decitabine of at least about 99.9:0.1. | 2014-04-03 |
20140094599 | Cellulose ethers having reactive anchor group, modified cellulose ethers obtainable therefrom and methods for the preparation thereof - Non-ionic water-soluble cellulose ethers modified with 3-azido-2-hydroxypropyl groups bound via an ether link are provided having a molar degree of substitution MS | 2014-04-03 |
20140094600 | Process for preparation of ketolide compounds - A process for the preparation of compound of Formula (I) is provided. Formula-I | 2014-04-03 |
20140094601 | Sulfonated dye salts having improved stability - A sulfonated dye salt is disclosed. The sulfonated dye salt has a phosphazene cation of formula (C): | 2014-04-03 |
20140094602 | HIGHLY PURE PENTAMYCIN - Described is pentamycin in a purity exceeding 95%, certain polymorphs and solvates of pentamycin, processes for their manufacture, and a method for decreasing the rate of degradation of pentamycin. | 2014-04-03 |
20140094603 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF - This invention relates to inhibitors of mitotic kinesins, particularly KSP, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharmaceutical compositions in the treatment and prevention of various disorders. | 2014-04-03 |
20140094604 | NEW INTERMEDIATES AND PROCESSES FOR PREPARING TICAGRELOR - The present invention is related to new intermediates and processes for preparing Ticagrelor disclosed in this patent application. | 2014-04-03 |
20140094605 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES - A synthesis approach providing an early ring attachment via a bromination to compound I-I yielding compound II-II: | 2014-04-03 |
20140094606 | RUTHENIUM COMPLEX FOR DYE-SENSITIZED SOLAR CELL - A ruthenium complex for a dye-sensitized solar cell includes a chemical formula represented by Formula (I): | 2014-04-03 |
20140094607 | TRANSITION-METAL-FREE SILYLATION OF AROMATIC COMPOUNDS - The present invention describes chemical systems and methods for silylating aromatic organic substrates, said system comprising a mixture of (a) at least one organosilane and (b) at least one strong base, said system being substantially free of a transition-metal compound, and said methods comprising contacting a quantity of the organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the aromatic substrate; wherein said system is substantially free of a transition-metal compound. | 2014-04-03 |
20140094608 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES - Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens. | 2014-04-03 |
20140094609 | PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR - The present invention is directed to an improved process for the preparation of Compounds of Formula (I), which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid, which is useful in the treatment of HIV infection. | 2014-04-03 |
20140094610 | PROCESS FOR THE PREPARATION OF AN HIV INTEGRASE INHIBITOR - The present invention is directed to an improved process for the preparation of Compounds of Formula (I) or salts thereof which are useful in the treatment of HIV infection. In particular, the present invention is directed to an improved process for the preparation of (2S)-2-tert-butoxy-2-(4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl)acetic acid or salt thereof which is useful in the treatment of HIV infection. | 2014-04-03 |
20140094611 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS - Provided herein are intermediates and processes useful for facile synthesis of biologically active molecules. | 2014-04-03 |
20140094612 | IMIDAZOLIDINE-BASED METAL CARBENE METATHESIS CATALYSTS - The present invention relates to novel metathesis catalysts with an imidazolidine-based ligand and to methods for making and using the same. The inventive catalysts are | 2014-04-03 |
20140094613 | PROCESS FOR PRODUCING 3-ALKOXY-2-AMINO-6-FLUOROBICYCLO [3.1.0] HEXANE-2,6-DICARBOXYLIC ACID DERIVATIVE AND INTERMEDIATE THEREOF - A process for producing a 3-alkoxy-2-amino-6-fluoro bicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative represented by the formula (I) or a salt thereof, which includes converting a compound represented by the formula (VI) or a salt thereof to the compound represented by the formula (I) or a salt thereof. | 2014-04-03 |
20140094614 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS - The present invention relates to novel amide derivatives of N-urea substituted amino acids, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the N-formyl peptide receptor like-1 (FPRL-1) receptor. | 2014-04-03 |
20140094615 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates - Provided are methods for making and using chiral, non-racemic protected organoboronic acids, including pinene-derived iminodiacetic acid (PIDA) boronates, to direct and enable stereoselective synthesis of organic molecules. Also provided are methods for purifying PIDA boronates from solution. Also provided are methods for deprotection of boronic acids from their PIDA ligands. The purification and deprotection methods may be used in conjunction with methods for coupling or otherwise reacting boronic acids. Iterative cycles of deprotection, coupling, and purification can be performed to synthesize chiral, non-racemic compounds. The methods are suitable for use in an automated chemical synthesis process. Also provided is an automated small molecule synthesizer apparatus for performing automated stereoselective synthesis of chiral, non-racemic small molecules using iterative cycles of deprotection, coupling, and purification. | 2014-04-03 |
20140094616 | PROCESS FOR PRODUCING ESTER COMPOUND - Compound (1) or a salt that is useful as an intermediate for the production of a medicine, an agrochemical or the like can be produced by a process including the following steps: (A) reacting an aldehyde (2) with nitromethane to produce a nitroaldehyde; (B) reacting the nitroaldehyde with an alcohol to produce a nitroacetal; (C) reducing the nitroacetal to produce an aminoacetal; (D) protecting an amino group in the aminoacetal to produce a protected aminoacetal; (E) treating the protected aminoacetal with an acid and subsequently with a base and then reacting the resultant product with a cyanating agent to produce a nitrile; (F) hydrolyzing the nitrile to produce a protected amino acid; and (G) substituting a group R | 2014-04-03 |
20140094617 | PLATE-TYPE REACTOR WITH IN-SITU INJECTION - A chemical reactor including: a plurality of heat exchange plates which between them define reaction compartments, in which reactor each heat exchange plate includes two walls between them defining at least one heat exchange space, the respective walls being fixed together by joining regions, and the reactor also comprises at least one injection device for injecting substance into the reaction compartments, said substance-injection device passing through the heat-exchange plates in respective joining regions thereof. Also, a chemical reaction process that can be carried out in this reactor. | 2014-04-03 |
20140094618 | CATALYTIC CONVERSION OF CELLULOSE TO LIQUID HYDROCARBON FUELS BY PROGRESSIVE REMOVAL OF OXYGEN TO FACILITATE SEPARATION PROCESSES AND ACHIEVE HIGH SELECTIVITIES - Described is a method to make liquid chemicals. The method includes deconstructing cellulose to yield a product mixture comprising levulinic acid and formic acid, converting the levulinic acid to γ-valerolactone, and converting the γ-valerolactone to pentanoic acid. Alternatively, the γ-valerolactone can be converted to a mixture of n-butenes. The pentanoic acid can be decarboxylated yield 1-butene or ketonized to yield 5-nonanone. The 5-nonanone can be hydrodeoxygenated to yield nonane, or 5-nonanone can be reduced to yield 5-nonanol. The 5-nonanol can be dehydrated to yield nonene, which can be dimerized to yield a mixture of C | 2014-04-03 |
20140094619 | ANDROSTANE AND PREGNANE STEROIDS WITH POTENT ALLOSTERIC GABA RECEPTOR CHLORIDE IONOPHORE MODULATING PROPERTIES - This invention describes compounds of Structures 1, 2, and 3 and their use as allosteric modulators of the GABA receptor chloride ionophore complex to alleviate stress, anxiety, mood disorders, seizures, depression, treatment of drug and alcohol abuse, memory, premenstrual disorders, and neural system damage. | 2014-04-03 |
20140094620 | PHOSPHORUS-SILICON SYNERGISTIC FLAME RETARDANTS AND THE PREPARTION METHOD AND USE THEREOF - The present invention discloses a phosphorus-silicon synergistic flame retardant and the preparation method and use thereof. The phosphorus-silicon synergistic flame retardant provided by the present invention has a structural general formula shown as formula I. A new type of compound containing phosphorus and silicon is prepared by the present invention using the cheap organic boron catalyst, and employing the addition reaction of diphenyl phosphine oxide and derivatives thereof with silicone containing carbon-carbon double bond. Such compounds have the properties of hydrolytic resistance, easy purification, and low synthesis cost, etc. Phosphorus and silicon elements in the molecular structures of such compounds both can act as the flame retardants solely, and meantime can work synergistically, thereby enduing the common polymeric materials with the excellent flame retardant property. | 2014-04-03 |
20140094621 | METHOD FOR PREPARING DIALKYL CARBONATE - The present invention provides a method for preparing dialkyl carbonate from urea or alkyl carbamate and alkyl alcohol using an ionic liquid comprising a cation, which produces a hydrogen ion, and a hydrophobic anion containing fluorine with high temperature stability in the presence of catalyst containing a metal oxide or hydrotalcite. Since the present invention can prepare dialkyl carbonate at a pressure lower than those of existing methods, it does not require an expensive pressure control device and peripheral devices for maintaining high pressure including the installation cost. It is also the method for preparing a dialkyl carbonate with high yield, thus improving economical efficiency. Moreover, the method of the present invention hardly produces any waste during the process and is thus an eco-friendly method. | 2014-04-03 |
20140094622 | PRODUCTION OF METHYL ACETATE FROM REACTANTS CONTAINING METHYL GROUPS - A method of producing methyl acetate from methanol in which methanol and carbon monoxide are reacted in a first reaction zone to provide a reaction product including methyl acetate, acetic acid, and unreacted methanol. The reaction product then is passed to a second reaction zone, wherein the acetic acid is reacted with the unreacted methanol to provide additional methyl acetate. The method is a more efficient method for producing methyl acetate from methanol in that acetic acid is not separated from the reaction product. | 2014-04-03 |
20140094623 | Method for Producing Bicyclic Compound via Claisen Rearrangement - The problem to be solved by the present invention is to provide a method for producing a compound having excellent activity as an α | 2014-04-03 |
20140094624 | Method for Producing Bicyclic Compound via Iminium Salt - The problem to be solved is to provide a method for producing a compound having excellent activity as an α | 2014-04-03 |
20140094625 | Process - The present invention relates to improved processes for the production of 2-amino-2-[2-(4-C | 2014-04-03 |
20140094626 | FLUIDIC CHANNEL COATED WITH METAL CATALYSTS AND DEVICES AND METHODS RELATING THERETO - The invention provides a method for coating fluidic channels, particularly millifluidic channels, with a catalyst coating having controlled dimensions and morphology, and methods for preparing such channels, and devices that can be used in combination with the channels. The invention further provides portable, hand-held millifluidic devices applicable for a wide variety of uses including molecular reduction reactions, in situ material characterization, in situ reaction catalysis characterization, in situ reaction mechanism characterization, nanomaterial synthesis, nanostructured metal and metal oxide growth and coating of channels, continuous flow cell culturing, enzymatic catalysis, biomolecular catalysis, combinatorial chemistry, reactions involving homogeneous catalysts bound to channel walls, peptide synthesis, nucleic acid synthesis, synthesis of pharmaceutical intermediates, biofunctionalization of nanomaterials or a combination thereof. | 2014-04-03 |
20140094627 | METHOD FOR PRODUCING 4,4'-DIFORMYLDIPHENYLALKANE - A method for producing a 4,4′-diformyldiphenylalkane represented by the following formula (2), containing formylating a diphenylalkane represented by the following formula (1) with carbon monoxide in the presence of hydrogen fluoride and boron trifluoride, in which the reaction temperature of the formylation is from −50 to 5° C., from 5 to 30 mol of hydrogen fluoride is used per 1 mol of the diphenylalkane, and from 1.5 to 5 mol of boron trifluoride is used per 1 mol of the diphenylalkane: | 2014-04-03 |
20140094628 | METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM - The subject of the present invention is a method for separating phenolic compounds in salified form from a reaction medium comprising them. The method of the invention for separating phenolic compounds in salified form from an aqueous reaction medium resulting from the reaction of a phenolic compound and of glyoxylic acid in the presence of a base leading to a reaction medium comprising at least the excess of initial phenolic compound in salified form and the various mandelic compounds in salified form resulting from the reaction, is characterized by the fact that said reaction medium is brought into contact with a basic anion-exchange resin that leads to the selective attachment of the initial phenolic compound to said resin and to the recovery of an aqueous stream comprising the mandelic compounds in salified form resulting from the reaction, and that the phenolic compound in salified form attached to the resin is separated by a resin regeneration treatment. | 2014-04-03 |
20140094629 | Process for Recovering Ethanol with Sidedraws to Regulate C3+ Alcohols Concentrations - Purification and/or recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid. Separation and purification processes of a crude ethanol mixture are employed to allow recovery of ethanol and remove impurities. In particular, the process involves one or more sidedraws to regulate C | 2014-04-03 |
20140094630 | RECYCLABLE EXTRACTANT COMPOSITIONS - Provided herein are processes comprising providing a fermentation medium comprising a fermentable carbon source, a recombinant microorganism comprising an engineered butanol biosynthetic pathway, and butanol; contacting said fermentation medium with an extractant composition comprising an effective amount of antioxidant or antioxidant-like compound, whereby at least a portion of the butanol in the fermentation medium partitions into the extractant; recovering at least a portion of the butanol and extractant composition from the fermentation medium; recycling the extractant composition recovered in (c) one or more times in the fermentation medium; optionally adjusting the effective amount of antioxidant or antioxidant-like compound in the extractant composition, whereby the rate of oxidation or effect of oxidized products in the recycled extractant composition is substantially reduced and/or avoided such that the extractant composition may be recycled. | 2014-04-03 |
20140094631 | Method for Production of Styrene from Toluene and Methane - A process is disclosed for making styrene by converting methanol to formaldehyde in a reactor then reacting the formaldehyde with toluene to form styrene in a separate reactor. | 2014-04-03 |
20140094632 | METHODS AND APPARATUSES FOR RECOVERING NORMAL HEXANE FROM REFORMATE STREAMS - Methods and apparatuses for recovering normal hexane from a reformate stream are provided. In one example, a method for recovering normal hexane from a reformate stream includes extracting aromatics from the reformate stream to form an aromatic extract stream and a raffinate stream. In the method, the normal hexane is separated from the raffinate stream to form a normal hexane product stream. | 2014-04-03 |
20140094633 | Alkylation of Aromatic Substrates and Transalkylation Process - A process for transalkylation of polyalkylated aromatic components can include providing a transalkylation reaction zone containing a transalkylation catalyst. A feedstock can be introduced into an inlet of the transalkylation reaction zone and into contact with the transalkylation catalyst. The feedstock can include a polyalkylated aromatic component derived from an aromatic substrate. The aromatic substrate can be supplied to the transalkylation reaction zone. The transalkylation reaction zone can be operated at temperature and pressure conditions sufficient to cause disproportionation of the polyalkylated aromatic component to produce a disproportionation product having a reduced polyalkylated aromatic content and an enhanced monoalkylated aromatic content. The disproportionation product can be withdrawn from the transalkylation reaction zone. Amounts of nitrogen containing compounds in the aromatic substrate can be monitored in a range of from 15 to 35 wppm by dry colorimetry. | 2014-04-03 |
20140094634 | DEVICE FOR DISTRIBUTING FEED AND RECOVERING EFFLUENS IN A RADIAL BED CATALYTIC REACTOR - The invention describes a radial bed catalytic conversion unit having an outer cylindrical chamber ( | 2014-04-03 |
20140094635 | METAL CATALYST COMPOSITION - Embodiments include metal catalyst compositions and methods of forming metal catalyst compositions. A metal catalyst composition can be formed by (a) contacting a supported metal catalyst surface with a ligand-containing alumina precursor for a predetermined contact time to form an intermediate layer having a plurality of aluminum moieties that chemically bond to the supported metal catalyst surface, optionally, contacting the intermediate layer of aluminum moieties with an inert gas for a predetermined intermediate stripping time to remove unreacted ligand-containing alumina precursors, (b) reacting the aluminum moieties with an oxidation reagent for a predetermined reaction time to convert at least a portion of the ligands to hydroxyl groups thereby forming a layer of the alumina over-coat on the supported metal catalyst surface or a previously formed layer of the alumina over-coat, (c) contacting the layer of the alumina over-coat formed in step (b) with an inert gas for a predetermined stripping time to remove unreacted oxidation reagents, replicating the sequential steps (a-c) to form an additional layer of the alumina over-coat, and (d) activating the alumina over-coat, after forming a final layer of the alumina over-coat, to form a plurality of pores therein. | 2014-04-03 |
20140094636 | AGGLOMERATED PARTICULATE LOW-RANK COAL FEEDSTOCK AND USES THEREOF - The present invention relates generally to processes for preparing agglomerated particulate low-rank coal feedstocks of a particle size suitable for reaction in a fluidized-bed reactor and certain other gasification reactors and, in particular, for coal gasification and combustion applications. The present invention also relates to an integrated coal hydromethanation process including preparing and utilizing such agglomerated particulate low-rank coal feedstocks. | 2014-04-03 |
20140094637 | FOCUSING A PARTICLE BEAM USING MAGNETIC FIELD FLUTTER - An example particle accelerator may include the following: a voltage source to sweep a radio frequency (RF) voltage in a cavity to accelerate particles from a plasma column, where the cavity has a magnetic field causing particles accelerated from the plasma column to move orbitally within the cavity, and where the magnetic field has flux that bows at edges of the cavity; a regenerator to provide a magnetic field bump within the cavity to thereby change successive orbits of the particles accelerated from the plasma column so that, eventually, particles output to an extraction point, where the regenerator is located at a radius in the cavity relative to the plasma column; and ferromagnetic arrangements located in the cavity proximate to the radius, where each ferromagnetic arrangement provides a magnetic field bump, and where ferromagnetic arrangements adjacent to the regenerator are separated from the regenerator by a space. | 2014-04-03 |
20140094638 | CONTROLLING INTENSITY OF A PARTICLE BEAM - In an example, a synchrocyclotron includes a particle source to provide pulses of ionized plasma to a cavity; a voltage source to provide a radio frequency (RF) voltage to the cavity to accelerate particles from the plasma column outwardly; and an extraction channel to receive a beam of particles from the cavity for output from the particle accelerator. The particle source is configured to control pulse widths of the ionized plasma in order to control an intensity of the beam of particles. This example synchrocyclotron may include one or more of the following features, either alone or in combination. | 2014-04-03 |
20140094639 | ADJUSTING ENERGY OF A PARTICLE BEAM - An example particle accelerator includes a coil to provide a magnetic field to a cavity; a particle source to provide a plasma column to the cavity; a voltage source to provide a radio frequency (RF) voltage to the cavity to accelerate particles from the plasma column, where the magnetic field causes particles accelerated from the plasma column to move orbitally within the cavity; an enclosure containing an extraction channel to receive the particles accelerated from the plasma column and to output the received particles from the cavity; and a structure arranged proximate to the extraction channel to change an energy level of the received particles. | 2014-04-03 |
20140094640 | Magnetic Field Regenerator - An example particle accelerator includes the following: a voltage source to provide a radio frequency (RF) voltage to a cavity to accelerate particles from a plasma column, where the cavity has a magnetic field causing particles accelerated from the plasma column to move orbitally within the cavity; an extraction channel to receive the particles accelerated from the plasma column and to output the received particles from the cavity; and a regenerator to provide a magnetic field bump within the cavity to thereby change successive orbits of the particles accelerated from the plasma column so that, eventually, particles output to the extraction channel. The magnetic field is at least 6 Tesla and the magnetic field bump is at most 2 Tesla. | 2014-04-03 |
20140094641 | Focusing a Particle Beam - An example particle accelerator includes the following: a resonant cavity in which particles are accelerated, where the resonant cavity has a background magnetic field having a first shape; and an extraction channel for receiving particles output from the resonant cavity. The extraction channel comprises a series of focusing regions to focus a beam of received particles. At least one of the focusing regions is a focusing element configured to alter a shape of the background magnetic field to a second shape that is substantially opposite to the first shape in the presence of a magnetic field gradient resulting from reduction of the background magnetic field from the resonant cavity to the extraction channel. | 2014-04-03 |
20140094642 | SKIN DOSE EVALUATION SUPPORT APPARATUS AND TREATMENT PLANNING APPARATUS - A skin dose evaluation support apparatus is provided with a skin region contour creation unit that creates skin region information including the boundary coordinates of a skin region, based on image data to be inputted when a treatment plan for a radiation therapy for a patient is created; and a display calculation unit that extracts a skin dose in a skin region, based on dose distribution data calculated by a dose distribution calculation unit of a treatment planning apparatus and the skin region information, and creates display data for displaying the extracted skin dose in a predetermined display format. | 2014-04-03 |
20140094643 | Controlling Particle Therapy - An example particle therapy system includes the following: a gantry that is rotatable relative to a patient position; a particle accelerator mounted to the gantry, where the particle accelerator is for outputting a particle beam essentially directly to the patient position; and a control system to receive a prescription and to generate machine instructions for configuring one or more operational characteristics of the particle therapy system. At least one of the operational characteristics relates to a rotational angle of the gantry relative to the patient position. | 2014-04-03 |
20140094644 | K-RING ELECTROMAGNETIC TREATMENT APPARATUS, SYSTEM AND METHOD FOR TUMORS, ARTHRITIS AND OTHER AILMENTS - A magnetic field therapy apparatus includes a first wire coil, a second wire coil and an electrically conductive member connecting the coils in series. The coils are wound in the same direction. In a preferred embodiment the coils are wrapped around a single bobbin, with the first coil forming a bottom layer and the second coil wrapped around the first coil and forming a top layer. AC power coupled to the coils energizes the coils and generates a magnetic field within the bobbin interior region. When current enters one coil it induces current in the other coil, thereby creating a scalar effect, producing energy in the form of a helix. The waves are identical, but out of phase temporally, that is, physically identical, but 180 degrees out of phase in terms of time. In an alternate embodiment, the coils may be on separate bobbins. A trigger may be applied to the part of a body undergoing therapy. | 2014-04-03 |
20140094645 | Methods, Systems, and Devices Relating to a Removable Percutaneous Interface Line - The various embodiments disclosed herein relate to percutaneous interface lines and related methods for implanting such lines. Each percutaneous interface line has an internal component coupleable to a percutaneous component with an internal connector. The percutaneous component can have a Y-shaped end having two arms, one arm having a lumen and another arm having at least one wire. The methods for implanting a percutaneous interface line include the use of a tunneling tool having a flexible rod and a replaceable dilator tip. | 2014-04-03 |
20140094646 | ADJUSTABLE FIXATION DEVICE HAVING REDUCED INFECTION - Components and portions of components of a hearing prosthesis encapsulated in a microorganism-barrier membrane. Methods and apparatus are described for implanting hearing prosthesis components in precise locations, and maintaining the locations, with at least some components or portions of components encapsulated in a microorganism-barrier membrane. | 2014-04-03 |
20140094647 | HEART WALL TENSION REDUCTION APPARATUS AND METHOD - Devices and methods for treatment of a failing heart by reducing the heart wall stress. The device can be one which reduces wall stress throughout the cardiac cycle or only a portion of the cardiac cycle. | 2014-04-03 |