15th week of 2011 patent applcation highlights part 30 |
Patent application number | Title | Published |
20110086698 | GAMING SYSTEM, A GAME CONTROLLER AND A METHOD OF GAMING - A gaming system comprising: a credit meter storing a balance of wagerable credits; a points meter storing a balance of usable points; a game play mechanism operable by the player to input a play instruction for a game comprising a credit portion and a points portion; and a game controller arranged to control conduct of the game in response to the play instruction based on the credit portion and the points portion and to determine whether to make an award of credits based on an outcome of the game. | 2011-04-14 |
20110086699 | AUTHORIZING AND MANAGING WAGERING AGENT ACCOUNTS - Described herein are processes and devices that authorize and manage wagering agents and associated accounts. One of the devices described is a wagering game system. The wagering game system can detecting a request from a first player account to utilize a shared wagering fund to wager on a wagering game. The shared wagering fund can be funded by a second player account. The wagering game system can make the shared wagering fund available to the first player account to wager on a wagering game. The wagering game system can determine a game award produced by the wagering game. The system can then allocate a portion of the game award to the second player account. | 2011-04-14 |
20110086700 | GAMING SYSTEM, A METHOD OF GAMING AND A JACKPOT GAME CONTROLLER - A system, and a method of gaming on the system. The method includes conducting a progressive jackpot game comprising a plurality of separate progressive jackpot prizes stored in respective ones of a plurality of jackpot meters, obtaining a jackpot increment; and updating the jackpot meters by selectively incrementing one of the jackpot prizes with the jackpot increment. | 2011-04-14 |
20110086701 | GAMING AWARD METHOD AND APPARATUS - A gaming system providing a tiered reward bonus promotion. A player's activity level is quantified to a value that adjusts over time. The value at the completion of a bonus period is compared to a plurality of tier values stored in memory at the central authority. Each tier value has an associated bonus award that is awarded to the player if the player reaches that tier at the completion of the bonus period. The award is indicated in the player's account and may be redeemed at a player kiosk. | 2011-04-14 |
20110086702 | METHOD AND SYSTEM FOR PROVIDING A VIRTUAL PRESENTATION INCLUDING A VIRTUAL COMPANION AND VIRTUAL PHOTOGRAPHY - A method and computer system for providing a virtual presentation is provided. A plurality of different groups of virtual objects within a virtual world on a display device, wherein at least one of the different groups is selectable by a user. The desired group of virtual objects are to be displayed within a virtual optical viewfinder. A selection tool is provided within the virtual optical viewfinder and is controllable by the user to select a target virtual object from the desired group of virtual objects displayed within the virtual optical viewfinder. The user is presented with a magnified image of the target virtual object and revealing an identity of the target virtual object that has been selected in response to selection of the target virtual object by the user. | 2011-04-14 |
20110086703 | OPTICAL SYSTEMS AND ELEMENTS WITH PROJECTION STABILIZATION AND INTERACTIVITY - Apparatus and method related to projections and/or computing devices are described. Projections may be made from multiple computing devices to create a presentation. Various other embodiments are described. | 2011-04-14 |
20110086704 | MUSIC GAME SYSTEM AND METHOD OF PROVIDING SAME - A method of providing a music game using a computer system includes the act of retrieving, from a storage medium coupled to the computer system, note information including timing information. The computer system includes a music game controller. The method also includes displaying, on a graphical user interface, a note indicator based on the note information. The method further includes receiving, by the computer system, an input from a music game controller, the input being indicative of a user playing a note in response to the note indicator. | 2011-04-14 |
20110086705 | MUSIC GAME SYSTEM AND METHOD OF PROVIDING SAME - A music game method includes retrieving song data having note information from a storage medium coupled to a computer system. The method also includes determining from the song data at least two note indicators to be presented sequentially and determining from the song data a leader between first and second note indicators. The leader provides information related to the second note indicator. A music game system includes a song manager module configured to retrieve song data having note information from a storage medium, and a user interface module configured to determine from the song data at least two note indicators to be presented sequentially and to determine from the song data a leader between first and second note indicators. Each note indicator is related to corresponding note information. The first and second note indicators are adjacent to one another. | 2011-04-14 |
20110086706 | Playing Browser Based Games with Alternative Controls and Interfaces - Methods, systems, and computer programs for playing browser based game with alternative controls and interfaces are presented. In one method, a definition of native inputs defined for the game is received. The native inputs are originated in a native device and are capable of causing actions in the game. Further, the method detects an alternate device that does not have all the native inputs. The native inputs are mapped from the native device to alternate inputs from the alternate device. The inputs generated with the alternate device are translated to corresponding native inputs according to the mapping and causing the corresponding actions in the game. In another method, a game area inside a web page is identified for playing the game. The game area is expanded by increasing the size of the game area while decreasing the size of other elements in the web page. | 2011-04-14 |
20110086707 | Transferable exercise video game system for use with fitness equipment - One embodiment of a wearable exergaming system comprised of control push-buttons and motion sensor worn by the player, communicating wirelessly with a portable computer/display placed on the fitness equipment in front of the player. This allows a fully portable exergaming system, that can be used on a number of different fitness machines, which is easily transferable from person to person and machine to machine. Other embodiments are described. | 2011-04-14 |
20110086708 | SYSTEM FOR TRACKING USER MANIPULATIONS WITHIN AN ENVIRONMENT - Systems, methods and for analyzing game control input data are disclosed. A machine-readable medium having embodied thereon instructions for analyzing game control input data is also disclosed. | 2011-04-14 |
20110086709 | ELECTRONIC SWORD GAME WITH INPUT AND FEEDBACK - Systems, methods, and apparatus for communicating information regarding movement of a gaming device are presented herein. A gaming device can include at least one sensor configured to measure information associated with at least one of a position of the gaming device or an attitude of the gaming device. Further, a communications interface component can be configured to communicate the information to a controller. A method can detect, via sensors of a handheld gaming device, information related to a movement of the handheld gaming device; and transfer the information to a controller communicatively coupled to the handheld gaming device. A system can include means for receiving information related to a position of a gaming device or an attitude of the gaming device, and means for predicting an anticipated position of the gaming device based on the means for receiving the information. | 2011-04-14 |
20110086710 | GAME APPARATUS AND STORAGE MEDIUM STORING GAME PROGRAM - A game apparatus comprises an obtaining means, a gravity direction calculating means, a first movement direction calculating means, and a game processing means. The obtaining means successively obtains acceleration data. The gravity direction calculating means calculates a gravity direction based on values of a plurality of pieces of acceleration data obtained during a predetermined period, where an orientation of an input device is used as a reference. The first movement direction calculating means calculates a first movement direction which is a movement direction of the input device, based on the values of the plurality of pieces of acceleration data obtained during the predetermined period, where the orientation of the input device is used as a reference. The game processing means executes a game process based on the first movement direction and the gravity direction. | 2011-04-14 |
20110086711 | Game Environment to Interact with Telephony Modem - A combination telephony and game device comprises a telephony modem for communicating with remote devices over a telephony network; and an application processor operatively connected to said telephony modem. The application processor is configured to execute a game application to play a game; receive a telephony event notification from said telephony modem while the game is being played; and represent, while the game is being played, the telephony event in a virtual reality environment provided by the game application. | 2011-04-14 |
20110086712 | ONLINE GAMES INTEGRATED WITH AN ONLINE GREEN MALL - An online gaming method for integrating offline and online activities. The method may include using a game server to receive a player identification code from one of the client devices that is operated by a game player, and the code may he provided to the player when they purchase a toy or product (e.g., a plush animal representing an endangered species). The method includes providing the client device access to an online game when the player identification code is verified and also includes storing in memory/data storage a player record for the game player. Then, the method includes receiving data indicating performance of an offline activity by the game player such as completion of a quantity of exercise. The game server then acts to modify the online game based on this received offline activity data such that performance of the offline activity is integrated into play of the online game. | 2011-04-14 |
20110086713 | GAME DEVICE - Disclosed is a game apparatus, including: a figurative object having a character identifying information; a reading section for reading a character information; a field section for freely moving the figurative object; a storage section for storing a plurality of display character identifying information; an identifying information reading section for reading the character identifying information from the figurative object at the reading section; a position reading section for reading position of the figurative object on the field; a display for displaying a character; and a controller for controlling the position of the character on the display, wherein when the figurative object is put on the field at a first time after the character identifying information has read by the identifying information reading section, the controller causes the display to display the character corresponding to the read character identifying information and controls the position of the character based on a read result of the position of the figurative object on the position reading section. | 2011-04-14 |
20110086714 | CONSTANT VELOCITY JOINT - A constant velocity joint includes an outer member defining an interior opening and a plurality comprising at least four grooves disposed within the interior opening and extending along a first longitudinal axis with each of the grooves being parallel to the other grooves and the first longitudinal axis, and an inner member disposed within the interior opening having a second longitudinal axis and defining a plurality of pockets corresponding to the grooves disposed radially about the second longitudinal axis with each of the plurality of pockets opposing one of the plurality of grooves. The joint further includes a plurality of drive balls corresponding to the grooves, each drive ball having a spherical shape and rotatably disposed within one of the plurality of pockets and moveably disposed within one of the plurality of grooves, wherein the outer member, inner member and plurality of drive balls comprise a constant velocity joint. | 2011-04-14 |
20110086715 | THREADED BOLT AND METHOD FOR ITS PRODUCTION - A threaded bolt may be produced according to a method including the steps of: forming a cylindrical bolt blank of metal with a root end and a head end, and with a section of the bolt blank adjoining the root end that is reduced in diameter up to a region designed for the formation of lead-in flights. Then, in a first rolling phase, partially form the principal thread flights and the lead-in thread flights using a first pass of flat jaws of a thread rolling machine. Then, in a second rolling phase, fully form the principal flights and the lead-in flights and forming grooves. | 2011-04-14 |
20110086716 | Novelty eye patch with artificial eye or eyelid - A novelty eye patch with a retaining, elastic band connected to a gag, false eye, eyelid or other embodiment, concealed beneath the patch. The patch and false eye or lid will be adjoined by a small, hidden spring, built onto two (2) hard wire frames. The spring will compress the false eye or lid against the user's real eye while allowing the patch to be lifted, revealing the gaff eye or lid. The two (2) steel wire frames will be concealed, along with the adjoining spring. One wire frame will be sewn into the outer circumference of the eye patch while the other frame will be molded into the underlying gaff or falsetto eye, to conceal their identity while maintaining stability to the patch and the gaff. Opposing force, created by the hidden spring, will compress downward the false eye or lid firmly against the user's real-eyelid, while maintaining a constant upward force of pressure on the patch. The spring will include a locking clip to keep the patch lowered to the position of the user's eye until such time that the user elects to lift the patch to reveal the gaff. This pressure will make lifting the patch more simplistic, while conversely maintaining an opposing force against the gaff eye or lid thereby preserving firmness of the gaff onto the user's real eyelid. | 2011-04-14 |
20110086717 | ADJUSTABLE HEIGHT SLIDE BASE - A playset is operable to be erected on a site and includes a slide and an adjustable-height slide base. The slide base includes an adapter that attaches below the slide and at least one standoff that attaches below the adapter. | 2011-04-14 |
20110086718 | Swing Seat - A swing seat assembly is provided for enhancing durability of the swing and increasing the safety of a person using the swing. The swing seat assembly includes an elongated seat element and a reinforcing member extending along the seat element. The reinforcing member is formed of a different material than the seat element and has a tensile strength that is greater than the tensile strength of the seat element. The assembly also includes a pair of rigid connecting elements configured to operably couple the seat element with suspending elements, where the connecting elements at least partially project from end margins of the seat element but do not extend inwardly beyond a top face of the seat element. A swing assembly is also provided that includes a reinforced swing seat with a reinforcing member extending therealong and being encased therein. The swing assembly includes a pair of suspending elements coupled to hooks projecting from end margins of the seat for suspending the seat from a playset frame. | 2011-04-14 |
20110086719 | SYSTEM FOR IMPROVED GOLF FLAG STICK STABILITY AND REDUCED GOLF CUP AND/OR FLAG STICK FERRULE WEAR - The subject matter described herein includes a system for improved golf flag stick stability and reduced golf cup and/or flag stick ferrule wear. The system includes a ferrule locatable on an end of a golf flag stick that is inserted in a golf cup. The ferrule has a top portion, a bottom portion, and a sidewall located between the top portion and the bottom portion, where the sidewall tapers inward at an angle selected from the range of 5 degrees to 30 degrees from the top portion to the bottom portion. The system further includes a golf cup having a central aperture for receiving the flag stick. The central aperture is defined by a sidewall that is tapered inward at an angle corresponding to an angle of the ferrule. | 2011-04-14 |
20110086720 | Device and Method for Monitoring the Striking Accuracy and the Swing Movement of a Golf Club - The device is used for monitoring the drive movement and the accuracy with which the striking surface ( | 2011-04-14 |
20110086721 | GOLF SWING TRAINING APPARATUS - A golf swing training apparatus includes a base, a supporting member extending from the base and a body restraining member slidably and pivotably coupled to the supporting member. A swivel mechanism detachably interconnects the supporting member to the body restraining member. The body restraining member includes a slide member with an enlarged cylindrical roller at one end. The swivel mechanism allows the cylindrical roller to be positioned to any height and any angular position within a substantially 360° range of motion. A pivotable supporting member may also be provided. | 2011-04-14 |
20110086722 | Golf Club Assembly and Golf Club with Suspended Face Plate - A golf club head includes a body member having a front surface, a major recess formed in the front surface, and a plurality of minor recess formed in a surface of the major recess. A face plate includes a front surface, a rear surface, and a plurality of projections extending outwardly from the rear surface. The face plate is received in the major recess, and each projection is received in a corresponding minor recess. A layer of resilient material may be disposed between each projection and the corresponding minor recess. | 2011-04-14 |
20110086723 | SET OF GOLF CLUBS - A set of golf clubs including golf club heads having improved mass distribution characteristics. The set includes golf club heads having a club head main body including a hitting face and a face support, a muscle back shell and a weight insert. | 2011-04-14 |
20110086724 | Universal Shaft and Head Connector - A connector for releasably securing a shaft and a head having a hosel with a bore of standard size. The connector includes a shaft adapter, a hosel adapter, and a compression nut. The shaft adapter has a shaft bore sized to receive the shaft, a first threaded coupling member, and a axial shaft. The hosel adapter has a hosel bore and a main body portion. The hosel bore is sized to receive the axial shaft. The compression nut has a second coupling member. The shaft is secured within the shaft bore and the main body portion is secured within the bore of the hosel using an adhesive and the axial shaft is inserted within the hosel bore. Thereafter, the compression nut is rotated to couple the first and second coupling members together thereby securing the shaft and head together without the shaft being received within the bore of the hosel. | 2011-04-14 |
20110086725 | Golf Club Head - The present invention provides a golf club head that can hit a ball with a sufficiently large amount of backspin. The golf club head according to the present invention is an iron type golf club head made of a metal and including a flat face. A plurality of traces are formed by milling on the face. The pitch of the traces is between 0.1 mm and 1 mm. | 2011-04-14 |
20110086726 | Iron-based alloy for a golf club head - An iron-based alloy for a golf club head includes: chromium in an amount ranging from 16.3 to 17.2 wt %; nickel in an amount ranging from 5.8 to 6.5 wt %; nitrogen in an amount ranging from 0.10 to 0.20 wt %; carbon in an amount ranging from 0.01 to 0.12 wt %; silicon in an amount ranging from 0.3 to 1.2 wt %; manganese in an amount ranging from 0.3 to 1.2 wt %; and a balance of iron and impurities, based on a total weight of the iron-based alloy. The alloy has a duplex-phase microstructure including a martensite phase and 10 to 30 percent austenite phase, and has a tensile strength greater than 120 Ksi and an elongation greater than 35%. | 2011-04-14 |
20110086727 | SOLID GOLF BALL - The present invention provides a solid golf ball that exhibits a high resilience performance and a high flight performance and gives a good shot feeling. The present invention relates to a solid golf ball including:
| 2011-04-14 |
20110086728 | COLOR GOLF BALL - The present invention is directed a golf ball having an overall golf ball color of pink or purple comprising a core, a cover and an intermediate layer, wherein at least one of the core, intermediate layer and cover comprises a pigment, dye, or tint which contributes to the color, the color having an a value, a b value and a hue angle value h expressed in the CIE CIECAM color system, wherein: where the a value is from about 5 to about 57, then the b value is from about −1 to about −60 and the hue angle h is from about 271° to about 359°; and where the a value is from about 58 to about 95, then the b value is from about 1 to about 60 and the hue angle h is from about 1° to about 35°. Alternatively, where the a value is from about 52 to about 58, then the b value may be from about −30 to about 30 and the hue angle h is either from about 330° to about 359° or from about 1° to about 30°. The color may also have a J lightness value expressed in the CIE CIECAM color system of from about | 2011-04-14 |
20110086729 | MOLDED POLYMER MATERIAL AND GOLF BALL - The invention provides a molded polymer material which is obtained by subjecting a polymer composition that includes (A) at least one polymer containing α,β-ethylenically unsaturated carboxylic acid, (B) at least one diene polymer, (C) at least one metal cation source, and (D) at least one organic peroxide, and has a chemical structure arrived at by neutralizing some or all of the carboxyl groups in component A with component C in the presence of component B, to molding and crosslinking under the influence of radicals generated by decomposing component D. The molded polymer material has a high resilience, a high hardness and a good durability, making it well-suited for use in golf balls. | 2011-04-14 |
20110086730 | BIODEGRADABLE SPORT OR GARDEN ARTICLES, AND APPARATUS FOR PRODUCING BIODEGRADABLE ARTICLES - A biodegradable sport or garden article such as a golf tee is formed from a material comprising filler material, which can contain grass seeds, and a degradable binder therefor, so that discarded tees enhance the surface of the golf course, rather than littering it. Apparatus for manufacture of such articles comprises respective storage containers ( | 2011-04-14 |
20110086731 | Method of Custom Fitting a Golf Club or Like Game Implement - A method of custom fitting a golf club or like implements having a shaft and a club head at a lower end thereof. The method utilizes the centerline of the shaft to determine the proper lie angle and true playing length for the shaft. A pointing device is attached to the shaft such that a projected point thereof is aligned with the centerline of the shaft to extend the centerline to the sole of the club head. The club head is placed on a universal setup mat with the club face aligned with the baseline thereof and the projected point on a target line where the sweet spot of the club head should hit a ball. A lie angle protractor on the mat is folded upward so the lie angle can be read from the protractor. The method also determines the proper grip size for the handle of the shaft. | 2011-04-14 |
20110086732 | SPORT GAME FOR PRESS SOCCER - A method of playing a Press soccer game on a field having a width of between 80 yards more or less for adult players to 60 yards more or less for children ten or younger. The field has touch lines that extend from a first goal arch line to a second goal arch line where the touch lines have a length of between 100 yards more or less for adults to 60 yards more or less for children ten or younger. The field has a goal zone area and a penalty arch line. One of the rules of play provides that a goal made without touching any other offensive player will count as two points when made from a goal zone area, three points when made within the penalty arch line, and four points when made from beyond the penalty arch line. | 2011-04-14 |
20110086733 | SPORTS TARGET DEVICE AND METHOD - An interactive sports target device is designed specifically to be suspended on the inside of a net attached to a goal. The target device emits an audible signal when impacted by a projectile such as a ball, puck or the like. The target device is light in weight to avoid deforming the net and can be easily attached or detached to the net in less than 30 seconds. The target device is reversible and can include both a front and rear with contrasting colors or designs. Both mechanical and electronic target devices are shown which provide a loud audible sound when struck by a projectile. Advanced electronic versions contain a programmable processor. | 2011-04-14 |
20110086734 | Baseball Bat - A baseball bat includes a hollow grip member having opposite front and rear ends, and an inner peripheral surface that defines a tapered chamber having a diameter reducing gradually toward the rear end. The inner peripheral surface has a first positioning portion disposed between the front end and the rear end. A striking member has an engaging segment received in the tapered chamber, and a large diameter segment extending forwardly from the engaging segment. The engaging segment has an axial hole, a plurality of open-ended slits extending along an axial direction and in spatial communication with the axial hole, and a second positioning portion aligned with the first positioning portion. A pressing member is inserted into the axial hole to press the second positioning portion against the first positioning portion. | 2011-04-14 |
20110086735 | FRICTION DRIVE BELT AND BELT TRANSMISSION SYSTEM USING THE SAME - A friction drive belt (B) includes a pulley contacting portion ( | 2011-04-14 |
20110086736 | LEAF CHAIN - A leaf chain comprises a plurality of links connected together, each of which includes two aligned rollers, at least one first inner plate provided with apertures to pivotally receive the rollers, and two outer plates fixed to the respective rollers and respectively positioned at external sides of the first inner plate. Wherein, two spacers are respectively disposed at both peripheries of the aperture on the first inner plate and annularly disposed on the rollers so as to block a leakage of a lubricant distributed over an interstice formed between each roller and each aperture. | 2011-04-14 |
20110086737 | THREE-MODE HYBRID POWERTRAIN WITH TWO MOTOR/GENERATORS - A hybrid electro-mechanical transmission connectable with multiple power sources for launching and propelling a vehicle includes an output member and a stationary member. The transmission also includes a first planetary gear set having a first, a second, and a third node, and a compound planetary gear arrangement having a fourth, a fifth, a sixth, and a seventh node. The power sources include an engine, a first motor/generator and a second motor/generator. The engine, the first motor/generator and the second motor/generator are each operatively connected with the first planetary gear set, and the output member and the second motor/generator are each operatively connected with the compound planetary gear arrangement. Thus configured, the transmission provides forward under-drive and forward direct-drive gears for launching and propelling the vehicle, as well as a reverse gear. | 2011-04-14 |
20110086738 | TRANSMISSION - In one embodiment, a transmission includes: a wobbler having an outer periphery tiltable with respect to a wobble axis of rotation; a set of freewheeling gears disposed in a fixed relationship with respect to one another, each gear having a gear axis of rotation about which the gear may rotate different from the gear axis of rotation of each of the other gears; one or both of the wobbler and the set of gears rotatable with respect to one another about the wobble axis of rotation; and each gear operatively connected to the wobbler simultaneously with the other gears at a place on the periphery of the wobbler different from the place at which each of the other gears is operatively connected to the wobbler such that each gear rotates on its axis of rotation as the wobbler wobbles or as the wobbler induces a wobble in another part. | 2011-04-14 |
20110086739 | HYBRID DRIVE DEVICE - A hybrid drive device includes a fluid clutch including an inputting element to which an engine torque outputted from an engine is inputted and an outputting element connected to an input shaft of a transmission to integrally rotate therewith for outputting the torque to the input shaft, the fluid clutch transmitting the torque between the inputting element and the outputting element via a fluid either with or without incrementing the torque, and a motor generator connected to the input shaft for outputting a motor torque to the input shaft to drive the transmission. | 2011-04-14 |
20110086740 | POWER TRANSMISSION APPARATUS AND POWER TRANSMISSION CONTROL APPARATUS - A power transmission apparatus disposed includes: a motor for driving wheels, and transforms kinetic energy at the driving path to electrical energy; a normal close type clutch that includes an input and an output and is selectively set in an engaging state and a released state, wherein the clutch is normally set in the engaging state by a biasing member and is set in the released state when hydraulic pressure is applied; a hydraulic-pressure feeding device for supplying the adjusted hydraulic pressure to the clutch; and a control device for controlling the feeding device. When changing the clutch from the engaged state to the released state, if the difference between rotation numbers of the input and the output becomes equal to or larger than the predetermined value, the control device controls the feeding device to bring the clutch to a state just before the engaged state. | 2011-04-14 |
20110086741 | STACKABLE MOTOR WITH FLEXIBLE MODES OF OPERATION - A vehicle comprises a drive sub-system having an engine and a first motor and a generator sub-system having a transmission and a second motor. The transmission for the vehicle is driven with the first motor, the second motor and the engine individually and in combination such that the vehicle may selectively operate in a serial hybrid mode and a parallel hybrid mode. | 2011-04-14 |
20110086742 | REHABILITATION AND EXERCISE MACHINE - An improved rehabilitation and exercise machine is provided which allows a person with physical limitations, disabilities or chronic conditions to use the machine in order to rehabilitate their muscles, improve joint flexibility, and enhance cardiovascular fitness. | 2011-04-14 |
20110086743 | Simulated Climbing and Full Body Exercise and Method - An apparatus and method permitting a user to perform a simulated climbing and full body exercise is provided. The design includes a frame and a pair of lever arms and a pair of foot platforms and a torso support. The frame is configured to place the operator's center of gravity in a position of falling away from the frame, lever arms, foot platforms and providing a torso support enabling the operator to be supported by hanging from the hands and supported by the feet and torso support. The frame may be rotated through varying angles from vertical permitting the operator's center of gravity to fall away from the frame and allow the operator to hang away from the frame further enhancing the climbing experience. | 2011-04-14 |
20110086744 | EXERCISE APPARATUS - The current invention is an exercise apparatus and method adapted for use with a leg exercising machine, the exercise apparatus including a base, a support beam having a proximal end and a distal end, wherein the proximal end portion extends from the base. Further included in the exercise apparatus is an omni-directional movable joint element that is disposed adjacent to the distal end portion and a grasping arm, with the grasping arm being received within the omni-directional movable joint element, wherein the grasping arm is operational to have omni-directional movement relative to the support beam. Also included in the exercise apparatus is a dampening element that is disposed between the support beam and the grasping arm, the dampening element is operational to dampen the omnidirectional movement such that an individual using the leg exercising machine can grasp the arm for stability and support for a soft skeletal joint support. | 2011-04-14 |
20110086745 | Multi-Functional Treadmill System - The present invention includes a treadmill system including a support platform, a liquid tank, and a lift support structure connected to a treadmill assembly by a lifting mechanism. In general, the liquid tank and the lift, support structure including the treadmill assembly move horizontally relative to and independent of one another along the support platform to position the lift support structure away from or about the liquid tank. In addition, the treadmill assembly moves vertically relative to and independent of the lift support structure using the lifting mechanism to lower or raise the treadmill assembly within an interior of the liquid tank or exterior of the liquid tank. More importantly, the combination of the horizontal movement and the vertical movement of the treadmill assembly permits a mammal to step onto the treadmill assembly before the treadmill assembly is raised and then lowered into an interior of the liquid tank. | 2011-04-14 |
20110086746 | RESISTANCE CHAIR WITH WHEELS - A resistance chair with wheels assists users with performing correct abdominal crunches by guiding the user's effort. The resistance chair includes a seat connected to a hinged back with back support that extends to support the user's back and assist in the crunch recovery following the crunch extension. | 2011-04-14 |
20110086747 | Exercise and video game chair - A video game chair for enhancing the enjoyment of a video game includes a chair member formed of a horizontal seat portion with a backrest portion vertically extending therefrom. This is a chair that utilizes arm movement, torso movement, leg movement and finger movement to control video games. The chair's movement is under resistance which is variable to suit the needs of the person playing the game. This resistance allows for a video gamer to benefit from extreme cardio and bodybuilding workouts while having their mind “in the game”. It is intended that this chair would be compatible with multiple video game consoles and computers | 2011-04-14 |
20110086748 | DRUM ROTATING DEVICE - A drum rotating device enables a drum and a driving device mounted in the drum to be supported with a simple structure and which reduces the possibility that the driving shaft of the driving device may be offset with respect to the rotation axis of the drum. The drum rotation device includes the drum and the driving device arranged to drive and rotate the drum. The drum includes an outer cylinder, an inner cylinder arranged inside the outer cylinder coaxially therewith, and a support wall arranged to connect the outer and inner cylinders to each other at an approximately intermediate portion in the axial direction. The outer and inner cylinders are substantially cylindrical. The driving device is fixed to a frame at one axial end. The driving shaft of the driving device extends through the drum and is rotatably supported by the frame through a bearing at the other axial end. The driving shaft is arranged to extend through the inner cylinder, thereby being fixedly attached the drum so that the drum and the driving shaft can rotate together. | 2011-04-14 |
20110086749 | MANUFACTURING MACHINE FOR PLASTIC CONTAINERS - A manufacturing machine for plastic containers having an upper and a lower portion with respective joining edges, comprising a first fixed base with an axle mounted thereto, a circular platform mounted upon the axle, and a plurality of welding stations mounted over the circular platform. Each welding station comprises a second fixed base that receives the lower portion of the container and a movable head having suction heads that receives the upper portion of the container therein, and it slides up and down upon a column mounted to the circular platform. The present invention further comprises a fusion station that acts upon the joining edges of the upper and lower portion and it comprises a hot plate that is positioned between the joining upper and lower edges and raises the temperature of the material, thus fusing the material. A robot loads new upper and lower portions into the welding station. | 2011-04-14 |
20110086750 | CORRUGATED SHIPPING CONTAINER SYSTEM WITH OVERLAPING SIDE PANELS HAVING A WIDTH AT LEAST SLIGHTLY LESS THAN THE WIDTH OF FOUR SIDE WALL PANELS - The present invention provides a cargo shipping crate having a base, four sides and a top cap, a first panel and a second panel. The first panel and the second panel form four sides of the crate. Each panel has a first, a second and a third subpanel. The first subpanel of the first panel is positioned to overlap the third subpanel of the second panel, and the second subpanel of the first and the second panel have substantially identical dimensions. The first subpanel of the first and the second panel have substantially identical dimensions, and the third subpanel of the first and the second panel have substantially identical dimensions. The top cap has four flaps, each of the four flaps are rotatable to a position superjacent a subpanel. | 2011-04-14 |
20110086751 | APPARATUS AND METHOD FOR SECURING AN END CAP TO A SHELL - An apparatus for securing an end cap including an end cap flange to a shell including a shell flange by forming a lip portion including the end cap flange and the shell flange into a lock seam portion in which the end cap flange and the shell flange are engaged with each other. The apparatus includes an elongate tool element rotatable about the central axis, for receiving the end cap thereon. The apparatus also includes a number of roller subassemblies for forming the lip portion into the lock seam portion. Each roller subassembly includes a forming roller engageable with the lip portion while the tool element rotates. Each roller subassembly also includes an arm on which the forming roller thereof is rotatably mounted, and a support mechanism for positioning the arm to engage the forming roller with the lip portion. | 2011-04-14 |
20110086752 | DYNAMICALLY BALANCED CHAMBER FOR CENTRIFUGAL SEPARATION OF BLOOD - A blood separation chamber for rotation about an axis comprises a low-G wall and a high-G wall extending about the axis in a spaced apart relationship to define between them a separation channel. The separation channel includes axially spaced first and second ends. The first end of the separation channel defines at least one generally arcuate recessed region and at least one radial wall within the recessed region sized and positioned so as to aid in balancing the blood separation chamber during rotation about the axis. | 2011-04-14 |
20110086753 | Method and System for Polishing Float Glass - A system for polishing a float glass used for liquid crystal displays includes a lower unit configured to rotate a float glass to be polished, a head assembly configured to be rotatable in contact with the float glass, and a moving unit configured to move the head assembly in a horizontal direction, wherein the head assembly includes at least two heads that are rotatable, respectively. | 2011-04-14 |
20110086754 | WETTING RESISTANT MATERIALS AND ARTICLES MADE THEREWITH - Ceramic materials with relatively high resistance to wetting by various liquids, such as water, are presented, along with articles made with these materials, methods for making these articles and materials, and methods for protecting articles using coatings made from these materials. One embodiment is an article comprising a material that is transparent to electromagnetic radiation of at least one type selected from the group consisting of ultraviolet radiation, visible light, and infrared radiation. The material comprises a primary oxide and a secondary oxide. The primary oxide comprises cerium or hafnium. The secondary oxide comprises (i) praseodymium or ytterbium, and (ii) another cation selected from the group consisting of the rare earth elements, yttrium, and scandium. | 2011-04-14 |
20110086755 | HYDROCRACKING CATALYST FOR HEAVY OIL - A catalyst for hydrocracking of heavy oil which comprises a support comprising crystalline aluminosilicate and a porous inorganic oxide excluding the crystalline aluminosilicate and an active metal supported on the support, wherein (a) the support comprises the crystalline aluminosilicate in an amount of 18% by mass or greater and smaller than 45% by mass and the porous inorganic oxide in an amount exceeding 55% by mass and of 82% by mass or smaller based on a sum of the amount of the crystalline aluminosilicate and the amount of the porous inorganic aluminosilicate, (b) the active metal is at least one metal selected from molybdenum, tungsten and nickel, and (c) the distribution of pores in the catalyst for hydrocracking of heavy oil is such that a volume of pores having a diameter of 500 to 10,000 Å is 10% or smaller and a volume of pores having a diameter of 100 to 200 Å is 60% or greater based on a volume of entire pores having a diameter of 50 to 10,000 Å. The catalyst exhibits excellent desulfurizing function and excellent activity for decomposition of fractions having a high boiling point of 525° C. or higher such as the vacuum residue. | 2011-04-14 |
20110086756 | METHOD FOR PREPARING SILICON INTERCALATED MONOLAYER GRAPHENE - A method of preparing the electronic material called silicon intercalated epitaxial monolayer graphene comprises the steps of growing large scale high-quality graphene on metal surface, depositing silicon on the prepared epitaxial graphene and annealing to high temperature to intercalate the silicon to the interface of graphene and metal surface. Depending on the quantity of the silicon deposited on the graphene surface, the numbers of the silicon layers on the interface can be controlled and adjusted. | 2011-04-14 |
20110086757 | DEOXIDIZER - A deoxidizer includes a porous body of fluorite-type cerium oxide represented by CeO | 2011-04-14 |
20110086758 | Fungicidal compositions comprising 3'-bromo-2,3,4,6'-tetramethoxy-2',6-dimethylbenzophenone - The present invention relates to a fungicidal compositions comprising 3′-bromo-2,3,4,6′-tetramethoxy-2′,6-dimethylbenzophenone. | 2011-04-14 |
20110086759 | CHEMICAL COMPOUNDS - The present invention relates to substituted pyrimidine derivatives of as well as N-oxides and agriculturally acceptable salts thereof, and their use to control undesired plant growth, in particular in crops of useful plants. The invention extends to herbicidal compositions comprising such compounds, N-oxides and/or salts as well as mixtures of the same with one or more further active ingredient (such as, for example, an herbicide, fungicide, insecticide and/or plant growth regulator) and/or a safener. | 2011-04-14 |
20110086760 | SUSPENSION CONCENTRATES IN OIL OF SULFONYLUREAS AND COMBINATIONS WITH FLUROXYPYR OR OTHER AGROCHEMICALS - Agricultural suspension in oil of Sulfonylureas and combinations with Fluroxypyr or other appropriate herbicides or agrochemicals are disclosed. The resulting formulations have improved stability regarding physicochemical properties of the formulation, as well as stability of the active ingredients allowing to make mixtures not yet available in the market. | 2011-04-14 |
20110086761 | COMPOSITIONS AND METHODS TO CONTROL OOMYCETE FUNGAL PATHOGENS - The present invention relates to fungicidal compositions and their use for controlling oomycete pathogen induced disease or diseases in one or more plants. | 2011-04-14 |
20110086762 | 4'4'-Dioxaspiro-Spirocyclically Substituted Tetramates - The present invention relates to novel 4′4′-dioxaspiro-spirocyclically substituted tetramates of the formula (I) | 2011-04-14 |
20110086763 | METHODS FOR MULTIPLEX AMPLIFICATION - Methods for multiplex amplification of target nucleic acid sequences are provided. | 2011-04-14 |
20110086764 | SINGLE TUBE MULTIPLEX ASSAY FOR DETECTION OF ADULTERANTS IN BASMATI RICE SAMPLES - The present invention provides a single tube multiplex assay for distinguishing basmati from non-basmati rice varieties, and thereby identifying the adulteration of basmati rice varieties. The present invention further provides a method for quantifying adulteration in basmati rice varieties. The present invention also provides a kit for performing a multiplex assay for distinguishing basmati from non-basmati rice varieties. The kit may comprise a primer directed to an SSR loci, appropriate reagents for PCR, and optionally, a package insert for conducting the assay. | 2011-04-14 |
20110086765 | GENE EXPRESSION PROFILING OF PRIMARY BREAST CARCINOMAS USING ARRAYS OF CANDIDATE GENES - Method for molecular characterization of a carcinoma including: (i) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a first group determining expression level of the polynucleotide from the first group to differentiate a tumor in which a lymph node has been invaded by a tumor cell from a tumor in which a lymph node has not been invaded by a tumor cell; (ii) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a second group determining expression level of the polynucleotide from the second group to distinguish tumors sensitive to anthracycline from tumors insensitive to anthracycline; (iii) detecting in tumor cells corresponding to breast tumor cells at least one polynucleotide selected from a third group determining expression levels of the polynucleotide from the third group to classify good and poor prognosis primary breast tumors. | 2011-04-14 |
20110086766 | Chemical and Biological Detection Arrays - Device comprising: a first substrate; a plurality of first raised elements on the first substrate, the first raised elements mutually spaced apart by first channel regions on the first substrate, each of the first raised elements having a first distal end, the first distal ends forming a first array; hydrophobic molecules on the first raised elements; and primary reactive molecules on the first raised elements for generating hydrophilic reaction products. Techniques for utilizing the device. | 2011-04-14 |
20110086767 | MUTANTS OF GLYCOSIDE HYDROLASES AND USES THEREOF FOR SYNTHESIZING COMPLEX OLIGOSACCHARIDES AND DISACCHARIDE INTERMEDIATES - Method for preparing the disaccharide α-D-glucopyranosyl-(1→4)-2-N-acetyl-2-deoxy-α-D-glucopyranoside, comprising the step of using a mutant of a wild type glycoside hydrolase. | 2011-04-14 |
20110086768 | TRANSFERRIN FUSION PROTEIN LIBRARIES - Fusion proteins comprising a transferrin moiety and integrin binding domain and peptide libraries thereof are disclosed. The present invention includes a method of screening transferrin and integrin peptide libraries displayed in fusion proteins expressed by host cells. The fusion proteins of the present invention include transferrin fusion proteins capable of expression in yeast. | 2011-04-14 |
20110086769 | METHODS AND GENOTYPING PANELS FOR DETECTING ALLELES, GENOMES, AND TRANSCRIPTOMES - Disclosed are methods and genotyping panels for detecting alleles, genomes, and transcriptomes in admixtures of two individuals. | 2011-04-14 |
20110086770 | Combinatorial Libraries Based on C-type Lectin-like Domain - This invention relates to polypeptide libraries comprising polypeptides having a C-type lectin domain (CTLD) with a randomized loop region, as well as nucleic acid libraries comprising nucleic acid molecules encoding such polypeptides. The invention also relates to methods for generating the randomized polypeptides and the polypeptide libraries. The invention further relates to methods of screening the polypeptide and nucleic acid libraries based on the specific binding of the modified CTLDs to a target molecule of interest. The invention also relates to polypeptides derived from such libraries that bind to target molecules of interest. | 2011-04-14 |
20110086771 | Biochip - Improved biochips comprise a matrix layer coupled to a substrate, wherein the matrix layer includes a plurality of ligands in a plurality of predetermined positions and wherein ligands bind to an anti-ligand disposed in a sample fluid. Preferred matrix layers are multi-functional matrix layers that reduce autofluorescence, incident-light-absorption, charge-effects, and/or surface unevenness of the substrate, and contemplated biochips may comprise additional matrix layers. Contemplated biochips may be useful in detection and/or quantification of various anti-ligands, including polypeptides, polynucleotides, carbohydrates, pharmacologically active molecules, bacterial or eukaryotic cells, and/or viruses. | 2011-04-14 |
20110086772 | MULTIPLEX (+/-) STRANDED ARRAYS AND ASSAYS FOR DETECTING CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH CANCER AND OTHER DISEASES - Multiplex (+/−) stranded analyses, such as array comparative genomic hybridization (aCGH), are provided for detecting chromosomal rearrangements associated with cancer and other diseases. For example, an illustrative multiplex array for CGH includes discrete plus (+) strand and minus (−) strand DNA probes, complementary to each other but separable on the CGH array. The minus (−) strand DNA probes recover diagnostic information lost to conventional microarrays, since many genes transcribe from the minus (−) strand. In an illustrative system, patient and control DNA samples are prepared for CGH by amplification and labeling using comprehensive primers that generate both plus (+) strands and minus (−) strands of DNA in the samples. The breakpoints of a translocated chromosome may be detected on a multiplex microarray by DNA probes of one polarity, while DNA copy number changes associated with the translocation region may be detected by corresponding DNA probes of the complementary polarity. Related methods for identifying translocation partner genes are also provided. | 2011-04-14 |
20110086773 | DIAGNOSTIC METHODS FOR ORAL CANCER - The invention provides for a diagnostic test to monitor cancer-specific genetic abnormalities to diagnose oral cell disorders and predict which patients might progress to cancer. Genetic abnormalities are detected by identification in chromosomal copy number of chromosome 3, chromosome 5 and chromosome 6 using FISH analysis of probes targeted to 3q and/or 5p and/or 11q. | 2011-04-14 |
20110086774 | Protein Detection Via Nanoreporters - The invention provides methods, compositions, kits and devices for the detection of proteins. In some embodiments, the invention allows for multiplexed protein detection. | 2011-04-14 |
20110086775 | H+-Gated Ion Channel - The invention relates to an isolated or recombinant Na | 2011-04-14 |
20110086776 | PROCESS AND METHOD FOR DIAGNOSING ALZHEIMER'S DISEASE - The present invention concerns methods and compositions usable for diagnosing Alzheimer's disease in mammals, in particular humans. It particularly describes serum markers for Alzheimer's disease and their use in diagnostic methods. It also concerns tools and/or kits usable for implementing these methods (reagents, probes, primers, antibodies, chips, cells, etc.), their preparation and their use. The invention is usable to detect the presence or progression of Alzheimer's disease in mammals, including in the early phase, as well as for predicting the efficacy of an Alzheimer's disease treatment. | 2011-04-14 |
20110086777 | METHOD FOR AUTISM PREDICTION - The present invention relates to a method for evaluating the level of risk for a subject to develop autism, or an autism spectrum disorder, which method comprises determining the number of risk alleles in autism-associated gene loci in a sample of a subject, wherein the more risk alleles are detected within said gene loci combined, the more increased is the risk of developing autism or an autism-spectrum disorder. | 2011-04-14 |
20110086778 | ENHANCED MICROPLATE CONFIGURATIONS - An enhanced microplate can include a base having a footprint with a length of 5 127.76 mm±1 mm and a width of 85.48 mm±1 mm. The base can be configured for an array of microwells having a base being configured for an array of micro wells such that there are ax rows along the width and ∥bx∥ columns along the length, where a is 8 or 9, b is 12, 13 or 14 provided that when b is 12, a is 9, and x is 0.5 or a positive integer. These enhanced microplates can be used to effectively increase throughput, decrease analysis time, and can be readily integrated into existing systems. | 2011-04-14 |
20110086779 | ARRAYS OF PROTEIN CAPTURE AGENTS AND METHODS OF USE THEREOF - Arrays of protein-capture agents useful for the simultaneous detection of a plurality of proteins which are the expression products, or fragments thereof, of a cell or population of cells in an organism are provided. A variety of antibody arrays, in particular, are described. Methods of both making and using the arrays of protein-capture agents are also disclosed. The invention arrays are particularly useful for various proteomics applications including assessing patterns of protein expression and modification in cells. | 2011-04-14 |
20110086780 | SYSTEM FOR FORMING AN ARRAY OF EMULSIONS - A system, including method and apparatus, for forming an array of emulsions. The system may include a plate providing an array of emulsion production units each configured to produce a separate emulsion and each including a set of wells interconnected by channels that intersect to form a site of droplet generation. Each set of wells, in turn, may include (1) at least one first input well to receive a continuous phase, (2) a second input well to receive a dispersed phase, and (3) an output well configured to receive from the site of droplet generation an emulsion of droplets of the dispersed phase disposed in the continuous phase. | 2011-04-14 |
20110086781 | METHOD FOR FORMING COMPOSITES OF SUB-ARRAYS OF FULLERENE NANOTUBES - The formation of arrays of fullerene nanotubes is described. A microscopic molecular array of fullerene nanotubes is formed by assembling subarrays of up to 10 | 2011-04-14 |
20110086782 | Controlling the formation of crystalline hydrates in fluid systems - Controlling the formation of crystalline hydrates in various fluid systems, most notably, gas and oil transmission pipeline systems by contacting the systems with certain polymers or polymers associated with solid particles. The polymers useful are chelating polymers capable of interacting with charged gaseous molecules such as carbon dioxide, by removing the carbon dioxide, or more practically by scavenging for the carbon dioxide, to prevent the methane or ethane hydrate structures from forming since they require carbon dioxide to stabilize their structures. | 2011-04-14 |
20110086783 | Air drilling misting fluid contains syrups - An air drilling misting fluid is provided and the fluid comprises: a continuous liquid phase solution comprising syrup, syrup solids and a first liquid medium, the syrup and syrup solids are derived from a group consisting essentially of agave syrup, barley syrup, sugar syrup, beets syrup, birch syrup, rice syrup, cane syrup, chocolate syrup, coconut syrup, corn syrup, date syrup, fruit syrup, golden syrup, high fructose corn syrup, inverted sugar syrup, karo syrup, citrus fruit syrup, maple syrup, molasses, Muscavado syrup, palm syrup, rice syrup, sorghum syrup, Turbinado syrup, vanilla syrup and mixtures and blends thereof; and a second liquid medium. | 2011-04-14 |
20110086784 | LUBRICANT - A lubricant containing one or more compounds selected from the keto compounds of general formula 1 | 2011-04-14 |
20110086785 | GREASE COMPOSITION FOR AUTOMOBILE WHEEL BEARING - The present invention provides a grease composition for automobile wheel bearings, which contains (a) an urea thickener represented by general formula (1); R | 2011-04-14 |
20110086786 | Stable aqueous slurry suspensions - A slurry composition for use as a lubricant and/or a stable suspension medium to suspend inert organic or inorganic particles which is an aqueous or polar solvent carrier containing gel particles as a lubricating and suspending agent for inert organic or inorganic particles. The composition can contain inorganic salts to provide additional electrostatic repulsion. | 2011-04-14 |
20110086787 | LUBRICATING COMPOSITION HAVING IMPROVED STORAGE STABILITY - A lubricating oil composition having superior storage stability and load-carrying effect is disclosed. The composition comprises four components: ( | 2011-04-14 |
20110086788 | BENEFIT AGENT CONTAINING DELIVERY PARTICLE - The present invention relates to benefit agent containing delivery particles, compositions comprising said particles, and processes for making and using the aforementioned particles and compositions. When employed in compositions, for example, cleaning or fabric care compositions, such particles increase the efficiency of benefit agent delivery, there by allowing reduced amounts of benefit agents to be employed. In addition to allowing the amount of benefit agent to be reduced, such particles allow a broad range of benefit agents to be employed. | 2011-04-14 |
20110086789 | MILD, FOAMING LIQUID CLEANSERS COMPRISING LOW LEVELS OF FATTY ISETHIONATE PRODUCT AND LOW TOTAL FATTY ACID AND/OR FATTY ACID SOAP CONTENT - The present invention relates to liquid personal care composition comprising both low levels of specific fatty isethionate product (e.g., less than 4%) and low overall fatty acid content (less than 4%) which, quite surprisingly, maintain excellent foaming profile relative to identical composition having high overall fatty acid content. | 2011-04-14 |
20110086790 | COMPOSITION INCLUDING ONE OR MORE HYDROLYTICALLY UNSTABLE COMPONENTS - A composition is provided suitable for use in a cleaning or washing process. The composition includes an activation agent for activating at least one aqueous sensitive component in use. The composition further includes a water soluble builder component and the activation agent is adsorbed onto a surface of the water soluble builder component. | 2011-04-14 |
20110086791 | SURFACE TREATMENT COMPOSITION CONTAINING PHOSPHONIC ACID COMPOUNDS - Surface treatment compositions containing selected phosphonic acid compounds are disclosed. The compositions contain major levels of surface-active agents in combination with additive levels of the phosphonic acid compounds, and, in accordance with needs and objectives, conventional optional ingredients and additive agents. The inventive compositions can provide significant performance benefits, among others novel synergies and eminently desirable regulatory and environmental acceptability. | 2011-04-14 |
20110086792 | PARTICLE CONTAINING ALKALI - The present invention relates to [1] alkali agent-containing particles which are free from deterioration of dissolvability in water and excellent in anti-caking property and which include (a) particles containing an alkali agent and having an average particle size of from 150 to 1000 μm, and a layer of (b) clay mineral particles exhibiting a water impregnation capacity of 200% by mass or more as calculated according to the following method and having an average particle size of from 1 to 200 μm, the layer being formed on a surface of the respective particles (a); and [2] a method for suppressing caking of the alkali agent-containing particles including the step of forming a layer of the clay mineral particles (b) on a surface of the respective particles (a): | 2011-04-14 |
20110086793 | PERFUME SYSTEMS - The present application relates to perfume systems and consumer products comprising new perfumes and/or such perfume systems, as well as processes for making and using such perfume systems and consumer products. | 2011-04-14 |
20110086794 | DELIVERY AGENT - A composition and method for delivering a peptide or protein into a cell. | 2011-04-14 |
20110086795 | Small peptide modulators of potassium channel trafficking - Provided herein are peptide modulators of ion channels. Specifically, the peptide modulators comprise the amino acid sequence VEDEC wherein V is valine, E is glutamate, D is aspartate, C is cysteine. In certain embodiments, the modulator is attached to the C-terminal end of Slo1 protein isoform. The present invention also claims conjugations of the first valine that make the peptide modulator more membrane permeable, such as myristoyl moieties and arginine-rich cell penetrating peptides. The present invention contemplates use of the peptide modulators in the treatment of diseases/malfunctions such as epilepsy, chronic pain, migraine, asthma, chronic obstructive pulmonary disease, urinary incontinence, hypertension, erectile dysfunction, irritable bowel syndrome, renal disorders of electrolyte imbalance, and possibly in certain kinds of cancer. | 2011-04-14 |
20110086796 | METHODS FOR PREDICTING THE DEVELOPMENT AND RESOLUTION OF ACUTE RESPIRATORY DISTRESS SYNDROME - The subject invention features methods for predicting whether a subject at risk of developing Acute Respiratory Distress Syndrome (ARDS) will develop ARDS by determining the amount of elafin present in a subject sample, or by determining the ration of elafin:neutrophil elastase in a subject sample. The invention also features methods for monitoring the efficacy of a treatment regimen for ARDS as well as methods of treatment for ARDS. The invention also features methods to determine a subject's predisposition for developing ARDS by determining whether certain genomic polymorphisms are present in the subject's DNA. | 2011-04-14 |
20110086797 | CONTROL OF SPORE GERMINATION - Provided are compositions and methods for treating bacterial infections. It is demonstrated herein that bacteria cell wall materials stimulate germination of spores of Gram-positive bacteria, and that such activity requires Ser/Thr kinase PrkC. By modulating one or both, spores (which can be antibiotic resistant) can be stimulated or inhibited from germination, which can be exploited in various methods of therapeutic treatment. Also provided is a method of modulating germination of a spore of a Gram-positive bacterium. Also provided is a method of decontaminating an environment. | 2011-04-14 |