15th week of 2016 patent applcation highlights part 18 |
Patent application number | Title | Published |
20160102226 | Curable Composition, Method Of Preparing Cured Article, And Cured Article Formed Thereby - A curable composition comprises a cationic polymerizable material. The curable composition further comprises a diluent component comprising a silane compound having a single silicon-bonded cationic polymerizable group. A method of forming a cured article with the curable composition is also disclosed. The method comprises applying the curable composition on a substrate to form a film. The method further comprises curing the film on the substrate to form the cured article. The present invention also provides the cured article formed in accordance with the method. | 2016-04-14 |
20160102227 | NICKEL PHOSPHOROUS CMP COMPOSITIONS AND METHODS - A chemical mechanical polishing (CMP) composition for planarizing a nickel phosphorus (NiP) substrate comprises a suspension of colloidal silica particles and fused silica particles in an acidic aqueous carrier containing hydrogen peroxide, in which the concentration of the fused silica particles is less than or equal to the concentration of the colloidal silica particles. In some embodiments, the CMP composition includes a primary complexing agent, a secondary complexing agent, and a metal ion such as ferric ion, which is capable of reversible oxidation and reduction in the presence of hydrogen peroxide and NiP. | 2016-04-14 |
20160102228 | ADHESIVE COMPOSITIONS AND THE USE THEREOF - The present invention relates to pressure sensitive hot melt adhesive compositions that comprise greater than about 15 wt % of a metallocene-catalyzed polyolefin random copolymer. The pressure sensitive hot melt adhesive has a heat of fusion less than 1.5 J/g and a peak glass transition temperature from −40° C. to 5° C. Crystallization in the adhesive is inhibited over time, and thus, the adhesive maintains a balance of peel and tack performances, making the adhesive particularly well suited for electronics, medical, industrial, graphics, construction and consumer goods applications. | 2016-04-14 |
20160102229 | OPTICAL FILM WITH PRESSURE SENSITIVE ADHESIVE AND PRODUCTION METHOD THEREOF, AND METHOD FOR PRODUCING IMAGE DISPLAY DEVICE - The optical film with a pressure sensitive adhesive comprises an optical film including a polarizing plate, a first pressure sensitive adhesive layer provided on first main surface of the optical film, and a second pressure sensitive adhesive layer provided on second main surface of the optical film. The first pressure sensitive adhesive layer has a thickness of 30 μm or more. In the first pressure sensitive adhesive layer, a fluidity of a pressure sensitive adhesive at an end surface is lower than a fluidity of the pressure sensitive adhesive at an in-plane central part. | 2016-04-14 |
20160102230 | Polyolefin-Based Hot Melt Adhesives With Improved Processing And Bonding Performance - A hot melt adhesive made from a blend of a polypropylene-based polymer, a polyolefin elastomer, and an amorphous polyolefin. These adhesives exhibit excellent molten and pre-set flow allowing them to wet out substrates yet develop properties needed to form and maintain strong bonds making them useful for hygiene, construction, and packaging applications. | 2016-04-14 |
20160102231 | COMPOSITIONS COMPRISING TETRAFLUOROPROPENE AND METHODS OF USE THEREOF - The present invention relates to a composition comprising HFO-1234yf, or trans-HFO-1234ze, or a mixture thereof; HFC-32; and HFC-152a, HFO-1243zf, or a mixture thereof, wherein said composition is selected from the group consisting of:
| 2016-04-14 |
20160102232 | Improved Phase Change Compositions - There are herein described phase change materials containing sodium acetate trihydrate having improved homogeneity, a process for the preparation of said materials, and their utility in phase change systems. More particularly, the present invention relates to the use of phase change compositions comprising sodium acetate trihydrate, at least one alkali soluble polymer for inhibition of sodium acetate anhydrous crystal formation in sodium acetate trihydrate containing phase change materials, and at least one sodium acetate trihydrate nucleation promoter, and, if a lower phase change temperature is required, at least one melting point depressing agent. | 2016-04-14 |
20160102233 | CORROSION INHIBITED COMPOSITIONS AND METHODS OF USING SAME - New compositions, for example, corrosion inhibited compositions, and the like compositions and new methods of using such compositions are disclosed. Such compositions may be liquid solutions, for example, substantially without solid material formation and/or crystal formation, and may include different concentrations of organic acid components and/or different combinations of organic acid components relative to previous compositions. The present compositions may be used as antifreeze coolant compositions or formulations, for example, in the cooling systems of internal combustion engines. | 2016-04-14 |
20160102234 | Extended Operation Engine Coolant Composition - The invention relates to an engine coolant composition, and a method of increasing the operational life of a coolant composition in an engine, wherein an isononanoic acid is incorporated into the generally glycol based coolant fluid in place of nitrous acid or its salt to reduce pitting corrosion on iron containing surfaces, and one or more hydroxybenzoic acids are incorporated. | 2016-04-14 |
20160102235 | Phase-Transition-Based Thermal Conductivity in Anti-Ferroelectric Materials - Thermal conductivity can be altered by applying an electric field to an antiferroelectric material or a pressure to a ferroelectric material, thereby inducing a phase transition. The materials have compositions close to a phase boundary separating the ferroelectric and antiferroelectric phases, such as PbZr | 2016-04-14 |
20160102236 | HYDROPHOBICALLY AND HYDROPHILICALLY MODIFIED POLYSACCHARIDES AND METHODS OF USING THE SAME FOR TREATMENT OF A SUBTERRANEAN FORMATION - The present invention relates to hydrophobically and hydrophilically modified polysaccharides and methods of using the same for treatment of a subterranean formation. In various embodiments, the present invention provides a method of treating a subterranean formation. The method includes obtaining or providing a composition including a hydrophobically and hydrophilically modified polysaccharide (HHMP). The method includes placing the composition in a subterranean formation. | 2016-04-14 |
20160102237 | WELLBORE SERVICING COMPOSITIONS AND METHODS OF MAKING AND USING SAME - A method of servicing a wellbore in a subterranean formation comprising preparing a wellbore servicing fluid comprising an alkoxylated humus material and an aqueous base fluid, wherein the alkoxylated humus material comprises an ethoxylated humus material and/or a C3+ alkoxylated humus material, and placing the wellbore servicing fluid in the wellbore and/or subterranean formation to modify the permeability of at least a portion of the wellbore and/or subterranean formation. A method of drilling a wellbore in a subterranean formation comprising preparing a drilling fluid comprising an alkoxylated humus material and an aqueous base fluid, wherein the alkoxylated humus material comprises an ethoxylated humus material and/or a C3+ alkoxylated humus material, and placing the drilling fluid in the wellbore and/or subterranean formation. | 2016-04-14 |
20160102238 | Wellbore Servicing Compositions and Methods of Making and Using Same - A method of servicing a wellbore in a subterranean formation comprising preparing a wellbore servicing fluid comprising cement, an aqueous fluid, and a cyclodextrin, a cyclodextrin derivative, or combination thereof; placing the wellbore servicing fluid in the wellbore and allowing the fluid to set. A wellbore servicing fluid comprising cement, aqueous fluid, and a cyclodextrin, cyclodextrin derivative, or combination thereof. | 2016-04-14 |
20160102239 | MICROEMULSIONS, MESOPHASE SURFACTANT AND MICELLAR SOLUTIONS, AND IN SITU-FORMED FLUIDS FORMULATED WITH HIGH DENSITY BRINE - Mesophase surfactant solutions and/or micellar solutions, pre-formed single phase microemulsions (SPMEs), and in situ-formed fluids may be used to clean up and remove hydrocarbons and synthetic oils such as oil-based mud filter cake and near wellbore damage in oil and gas wells. Removal occurs by solubilization of the hydrocarbons and synthetic oils into the micellar solutions, SPME, in situ-formed fluids, etc. when the fluid formulation contacts the hydrocarbons and synthetic oils. An in situ-formed fluid (e.g. microemulsion), may be formed when one or more surfactant, an optional linker, optional co-surfactant, optional acid, optional cosolvent and a polar high-density brine phase, and eventually some amount of organic phase, contacts the subterranean location and solubilizes the hydrocarbons and synthetic oils encountered, such as in the near wellbore of a subterranean formation. The micellar solutions, microemulsions, in situ-formed fluids, etc. are effective for removing the formation damage caused by hydrocarbons and synthetic oils. | 2016-04-14 |
20160102240 | MULTI-TAIL HYDRATE INHIBITORS - Low-dosage hydrate inhibitor (“LDHI”) compounds comprising multiple lipophilic tails and a hydrophilic head may be employed into fluids to inhibit agglomeration of hydrates, among other things. Suitable hydrophilic heads may include quaternary or tertiary ammonium cation moieties, and combinations thereof. Such LDHI compounds in some embodiments may include reaction products of DETA and/or other amines, fatty acid(s), and, optionally, alkyl halide(s). Compounds according to some embodiments may be employed in fluids in various environments, such as a conduit penetrating a subterranean formation, or a conduit carrying fluid in an industrial setting. | 2016-04-14 |
20160102241 | HEAVY CRUDE OIL VISCOSITY REDUCER - A viscosity reducer based on vegetable extracts of natural origin is disclosed. The vegetable extracts include a mixture of phosphoglycerides and vegetable oils. A method of reducing the viscosity in heavy and extra heavy crude oil using the viscosity reducer is also disclosed. No aromatic base solvents are needed. A reduction in diluent usage is achieved using the viscosity reducer based on vegetable extracts. The viscosity reducer composition includes a mixture of phosphoglycerides, vegetable oil, non-aromatic solvent, polycyclic aromatic hydrocarbon and stabilizer. | 2016-04-14 |
20160102242 | TREATMENT FLUID AND METHOD - A treatment fluid made of mineral acid, viscoelastic surfactant, at least one of a fluoride source and a chelant, and optionally a corrosion inhibitor. A method of combining a mineral acid, viscoelastic surfactant, at least one of a fluoride source and a chelant, and optionally a corrosion inhibitor, in a fluid mixture. A method of contacting a low-temperature formation with a fluid mixture of mineral acid, viscoelastic surfactant, at least one of a fluoride source and a chelant, and optionally a corrosion inhibitor. | 2016-04-14 |
20160102243 | EXPANDABLE PROPPANT - A method of treating a subterranean formation includes injecting an expandable proppant fluid into a wellbore, wherein the expandable proppant fluid comprises an expandable material; introducing the expandable proppant fluid into the subterranean formation through the wellbore; and increasing the diameter of the expandable material in the expandable proppant fluid from a first diameter to a second diameter after introduction into the subterranean formation. | 2016-04-14 |
20160102244 | DEGRADABLE FIBER FOR USE IN WELL TREATMENT FLUID, METHOD FOR MANUFACTURING SAME, AND WELL TREATMENT METHOD - A fiber formed from a resin that degrades in treatment fluid for hydrocarbon resource recovery, an oligomer component content of a resin forming an outer surface of the fiber being not greater than 1 mass %, and a birefringence of the fiber being not less than 0.02; a method for manufacturing a degradable fiber for use in well treatment fluid, the oligomer component content of a resin that forms an outer surface of an undrawn yarn obtained in a spinning step being not greater than 1 mass %, and a birefringence of a drawn yarn before heat treatment in a drawing step being not less than 0.02; and a well treatment method using the well treatment fluid containing the degradable fiber for use in well treatment fluid and a proppant. | 2016-04-14 |
20160102245 | PARTICLE COATING PROCESS AND COMPOSITIONS FOR CERAMIC PROPPANT EXTRUSION - Methods include providing an aqueous slurry of ceramic forming raw materials, where at least a portion of the ceramic forming raw materials are enhanced particulates, and flowing the slurry through at least one extrusion die face to form slurry bodies while the slurry is under a hypotensive condition which is less than about 30 kPa, or otherwise pressure lower than conventional extrusion pressures using unenhanced raw materials. The slurry bodies may then be received in a collecting hopper, and thereafter sintering to form particles, such as ceramic proppant particles. Enhanced particulates may be raw material particulates that are coated, selectively shaped, of particular size(s), or any combination thereof. | 2016-04-14 |
20160102246 | Stabilization of High Molecular Weight Polysaccharide Solutions at High Temperatures - A fluid mixture containing a high molecular weight polysaccharide composition with improved viscosity stability at high downhole temperatures and pressures encountered in common oil field applications, including hydraulic fracturing stimulation, drilling, cementing, and coil-tubing. The composition includes a salicylic acid solution, which, being a free-radical scavenger, prevents free-radical reactions within the high molecular weight polysaccharide that would otherwise adversely affect viscosity. The composition may also include an ascorbic acid solution, which reduces at least a portion of the oxidized salicylic acid to restore its function as a free-radical scavenger to prevent additional free-radical reactions with the high molecular weight polysaccharide. An alcohol solvent may also be utilized to increase the solution loading of salicylic acid. | 2016-04-14 |
20160102247 | PLASTIC SCINTILLATORS WITH HIGH LOADING OF ONE OR MORE METAL CARBOXYLATES - According to one embodiment, a method includes incorporating a metal carboxylate complex into a polymeric matrix to form an optically transparent material. According to another embodiment, a material includes at least one metal carboxylate complex incorporated into a polymeric matrix, where the material is optically transparent. | 2016-04-14 |
20160102248 | PHOTOLUMINESCENT COMPOUNDS - Materials comprising an A/M/X compound are provided. An A/M/X compound is a compound comprising one or more A moieties, one or more M atoms and one or more X atoms, where the A moieties are selected from organic cations and elements from Group 1 of the periodic table, the M atoms are selected from elements from Group 14 of the periodic table, and the X atoms are selected from elements from Group 17 of the periodic table. The materials include two-phase materials. | 2016-04-14 |
20160102249 | PHOSPHOR AND METHOD FOR PRODUCING SAME - The object of the present invention is to provide an oxide-based phosphor comprising elements other than rare earth elements as light-emitting elements, with low material costs, while achieving high luminous efficacy. The means for achieving the object is a phosphor comprising the following (1) to (3): (1) zirconium oxide, (2) titanium, and (3) at least one element selected from the group consisting of phosphorus, selenium, boron, and silicon. | 2016-04-14 |
20160102250 | REVERSE OSMOSIS FOR PURIFYING MIXTURES OF HYDROFLUORIC ACID AND NITRIC ACID - Disclosed is a method of purifying a solution containing hydrofluoric acid, nitric acid and at least one silicon impurity by treating the solution with at least one reverse osmosis membrane. According to the method of the present invention, silicon impurities contained in the solution containing hydrofluoric acid and nitric acid can be selectively removed or reduced. This method can be advantageously used in the photovoltaic industry or in the battery component industry. | 2016-04-14 |
20160102251 | MICROBIAL COMPOSITIONS AND METHODS - The present invention comprises compositions and methods for enhancing biological processes, such as plant growth or bioremediation. For example, the present invention comprises compositions and methods for effectively remediating chemical and organic wastes and reducing the environmental risk from manure, septic, sewage, oil pollution, and other contaminants. | 2016-04-14 |
20160102252 | METHOD FOR PRODUCING COMPOSITION - A raw material composition containing a hindered phenol compound having a specified structure and a compound constituting a liquid crystal material is prepared, the raw material composition is brought into contact with a purifying agent after being dissolved in an organic solvent or without the addition of an organic solvent to the raw material composition, and then the purifying agent is removed, and when a composition after the purifying agent is removed does not contain the organic solvent, the composition is provided as a target composition, and when the composition after the purifying agent is removed contains the organic solvent, the organic solvent is distilled off to provide a target composition. | 2016-04-14 |
20160102253 | DELAYED COKER FEED HEATER ON-LINE STEAM-CHEMICAL DECOKING METHOD - A process for decoking of delayed coker feed heater pass is disclosed. A chemical mixture containing a metal hydroxide and a metal carbonate is combined with steam to decoke the delayed coker feed heater pass. | 2016-04-14 |
20160102254 | ELECTROSTATIC FILTRATION OF FINE SOLIDS FROM BITUMEN - Methods are provided for removing fine particles from crude oils extracted from mined oil sands using a non-aqueous extraction solvent. A bitumen derived from non-aqueous extraction of oil from oil sands can undergo optional physical separation to remove larger particles and then processed using electrostatic filtration to remove particle fines. This can allow for production of a bitumen product from a non-aqueous extraction process that has a sufficiently low particle content to be suitable for pipeline transport. | 2016-04-14 |
20160102255 | Integrated Heavy Liquid Fuel Coking With Chemical Looping Concept - A process for power generation using a chemical looping combustion concept is integrated with heavy liquid fuel coking in a cracking reactor, and is configured such that petcoke deposits on metal oxide particles from the cracking reactor are used as fuel in the chemical looping combustion reaction. The process is also configured such that metal oxide particles provide the heat necessary for the cracking reaction to be initiated in the cracking reactor. | 2016-04-14 |
20160102256 | METHODS AND APPARATUSES FOR SELECTIVE HYDROGENATION OF OLEFINS - Methods and apparatuses for selective hydrogenation of olefins are provided. The method for selective hydrogenation of olefins comprises reacting a hydrocarbonaceous feedstock comprising olefins and aromatic compounds with hydrogen in a reaction zone. The reaction contains a catalyst producing a reaction zone product stream comprising aromatic compounds. The reaction zone product stream is passed to a flash vessel, recovering a first product stream and a second product stream from the flash vessel. The first product stream is passed to a liquid jet eductor, whereas the second product stream comprising aromatic compounds having a reduced concentration of olefins is subsequently recovered. | 2016-04-14 |
20160102257 | METHODS AND SYSTEMS FOR RECOVERY OF HYDROCARBONS FROM FLUID CATALYTIC CRACKING SLURRY - Methods and systems for recovering a hydrocarbon from fluid catalytic cracking (“FCC”) slurry and for separating a FCC slurry stream from a FCC effluent are provided. An exemplary hydrocarbon recovery method comprises the steps of: contacting a feed with a catalyst in a FCC reactor under conditions suitable to crack one or more hydrocarbons and generate a FCC effluent; separating the FCC effluent with a fractionation column to generate a product stream and a FCC slurry that collects in a lower portion of the fractionation column; drawing a first FCC slurry stream at a first temperature from a first location in the fractionation column; drawing a second FCC slurry stream at a second temperature from a second location in the fractionation column, and separating a hydrocarbon from the second FCC slurry stream, wherein the second temperature is higher than the first temperature. | 2016-04-14 |
20160102258 | PROCESS AND APPARATUS FOR SELECTIVELY HYDROGENATING NAPHTHA - The process and apparatus of the present invention selectively hydrogenates a heavier olefinic naphtha stream in an upstream catalyst bed and the hydrogenated effluent and a lighter olefinic naphtha stream in a downstream catalyst bed. The heavier di-alkenes are less re-active and are contacted with more hydrogenation catalyst than the lighter di-alkenes which are more re-active. | 2016-04-14 |
20160102259 | REFORMING METHANE AND HIGHER HYDROCARBONS IN SYNGAS STREAMS - Oxygen is added to a raw syngas stream that contains hydrogen and CO, one or more light hydrocarbons, and that may also contain tars, produced by gasification of carbonaceous feed material, while imparting heat at a rate greater than 125 BTU per pound of oxygen added, to partially oxidize light hydrocarbons and convert tars if present to lower molecular weight products. | 2016-04-14 |
20160102260 | Efficient Volatile Metal Removal from Low Rank Coal in Gasification, Combustion, and Processing Systems and Methods - Efficient coal pre-processing systems ( | 2016-04-14 |
20160102261 | DEHYDRATION OF LIQUID FUEL - A method for dehydrating liquid fuel, the method comprising injecting a supply of dry gas into a liquid fuel via an outlet submerged in the liquid fuel. Also, a system for dehydrating liquid fuel, the system comprising a container for storing a liquid fuel, a line for delivering a supply of dry gas, and an outlet disposed near the bottom of the container and connected to the gas line for injecting dry gas into the liquid fuel. | 2016-04-14 |
20160102262 | SYSTEM AND METHOD FOR SUBSEA COOLING A WELLHEAD GAS TO PRODUCE A SINGLE PHASE DEW-POINTED GAS - A system and method for subsea cooling a wellhead gas containing components separable by dewpoint condensation to produce a single phase dew-pointed gas for pipeline transport is disclosed. The system includes a first cooling apparatus configured in use to cool the wellhead gas in direct or indirect heat exchange relation with ambient seawater to a first temperature marginally above ambient seawater temperature to condense liquids comprising one or more hydrocarbons other than methane and at least partially condense water in the wellhead gas. The system also includes a first separator to separate the condensed liquids and water from the cooled gas and a means to add a hydrate inhibitor into the separated cooled gas. The system further includes a second cooling apparatus configured to cool the separated cooled gas to a second temperature below the first temperature, wherein the second temperature is below the ambient seawater temperature to condense the remaining water and produce a single phase dew-pointed gas; and a second separator to separate the condensed remaining water from the single phase dew-pointed gas. | 2016-04-14 |
20160102263 | FLUIDIZABLE ALGAE-BASED POWDERED FUEL AND METHODS FOR MAKING AND USING SAME - An algae-based powdered fuel is configured to be fluidized in a gas stream. The algae-based powdered fuel is manufactured by drying an algae slurry to produce a powdered composition and then comminuting the powdered composition to produce the fuel. The algae-based powdered fuel can be combusted in a gas turbine to generate electricity and/or to propel an aircraft. | 2016-04-14 |
20160102264 | SOLID FUEL COMPOSITIONS CONTAINING LIGNOCELLULOSIC SYRUP AND COAL FINES - A pelletized fuel composition is made from a mixture of coal fines, and cellulosic by-product from ethanol production. The coal fines range from about 50%-90% by weight and the cellulosic by-product ranges from about 10%-50% by weight of the composition. The cellulosic by-product is a syrup or a cake. The syrup binds the coal fines. The coal fine and syrup mixture is pelletized to produce a solid fuel product that is easily handled and transported. | 2016-04-14 |
20160102265 | Polyalkylene Glycol-Grafted Polycarboxylate Suspension and Dispersing Agent for Cutting Fluids and Slurries - Cutting fluids for brittle materials, e.g., silicon ingot, comprise, in weight percent:
| 2016-04-14 |
20160102266 | Phosphorous-Containing Compounds and Uses Thereof - The present invention provides phosphorous-containing compounds useful as antiwear additive components, lubricant additive compositions and lubricant compositions each comprising such compounds, and methods for making and using the same. | 2016-04-14 |
20160102267 | CRUDE OIL FRICTION REDUCER - A crude oil friction reducer is disclosed. The friction reducer includes water soluble anionic surfactants as active components and non-aromatic solvents. The water soluble anionic surfactants include anionic sulfonate surfactant and an anionic sulfate surfactant, such as anionic sodium sulfate surfactant, dissolved in an aqueous chelating solution. The friction reducer may also include a pH adjuster. The friction reducer is used with heavy and extra heavy crude oil. | 2016-04-14 |
20160102268 | DRILLING FLUID SYSTEM - An aqueous based metalworking fluid that is environmentally friendly and process for metalworking with the fluid. The metalworking fluid is sampled at periodic intervals and replenished to predetermined operating specifications with the aqueous based metalworking fluid without the need for individual boosters. | 2016-04-14 |
20160102269 | CORN STILLAGE OIL DERIVATIVES - Corn stillage oil derivatives having values for Gardner color of 10 or less and methods for making the corn stillage oil derivatives are disclosed. In one aspect, the corn stillage oil derivative comprises a heat bleached corn stillage oil. Preferably, the heat bleached corn stillage oil has a value for Gardner color of from 4 to 8. In another aspect, the corn stillage oil derivative comprises a blown corn stillage oil. Preferably, the blown corn stillage oil has a value for Gardner color of from 5 to 8. | 2016-04-14 |
20160102270 | BLOWN CORN STILLAGE OIL - Blown corn stillage oils and methods for making blown corn stillage oils are disclosed. In one aspect the corn stillage oils are stripped to reduce the acid value of the resulting blown, stripped corn stillage oil. The method includes heating a corn stillage oil to a temperature of at least 90° C., and passing air through the heated oil to produce a blown corn stillage oil having a viscosity of at least 50 cSt at 40° C. In one aspect, the blown corn stillage oil is stripped to reduce the acid value of the blown, stripped corn stillage oil to 5 mg KOH/gram or less. | 2016-04-14 |
20160102271 | ALKOXYLATED FATTY ESTERS AND DERIVATIVES FROM NATURAL OIL METATHESIS - Alkoxylated fatty ester compositions are disclosed. In one aspect, the compositions comprise a reaction product of a metathesis-derived C | 2016-04-14 |
20160102272 | LAUNDRY DETERGENTS BASED ON COMPOSITIONS DERIVED FROM NATURAL OIL METATHESIS - Laundry detergents useful for cold-water cleaning and boosted bargain detergents are disclosed. The detergents include a surfactant composition derived from a metathesis-derived C | 2016-04-14 |
20160102273 | FABRIC ENHANCER COMPOSITION - A fabric enhancer composition comprising at least 0.1% by weight of fabric softening active of formula (A): | 2016-04-14 |
20160102274 | DETERGENT BUILDER AND DISPERSANT SYNERGY IN CALCIUM CARBONATE SCALE PREVENTION - Cleaning compositions are provided. The cleaning compositions can include a builder and a dispersant. The cleaning compositions can include one or more additional components. The cleaning compositions can be used in cleaning applications such as automated dishwashing. | 2016-04-14 |
20160102275 | USE OF ACTIVATOR COMPLEXES TO ENHANCE LOWER TEMPERATURE CLEANING IN ALKALINE PEROXIDE CLEANING SYSTEMS - The present invention provides for the use of activator complexes to enhance lower temperature cleaning in alkaline peroxide cleaning systems. Compositions including at least one of an activator complex, an active oxygen source, and a source of alkalinity are applied to the surface to be cleaned at temperatures between about 5° C. and about 50° C. The methods and compositions of the present invention provide for enhanced soil removal with reduced energy, water, and chemistry consumption. | 2016-04-14 |
20160102276 | BLEACH AND OXIDATION CATALYST - The present invention concerns a method of making manganese ion-containing catalyst salts, which comprise a mononuclear or dinuclear Mn (III) and/or Mn (IV) complex based on cyclic triamine ligands and a non-coordinating silicate-based counterion. The invention also concerns compositions comprising such salts and bleaching formulations comprising the salt and a peroxy compound. The salt, and formulations comprising it, are suitable for use in catalysing oxidation, for example as a component of a laundry or dishwasher bleaching composition. The invention further relates to methods of oxidising with the bleaching formulations described herein. | 2016-04-14 |
20160102277 | METHOD OF CLEANING SOLAR PANELS - A method for cleaning the glass surface of solar panels which employs the use of highly efficient sequestering agents and allows to replace deionized water with municipal or fresh water of up to a very high water hardness, without having a loss in the long term power output of the solar panels. | 2016-04-14 |
20160102278 | Articles Comprising Water-Soluble Polyvinyl Alcohol Blend Film and Related Methods - Articles that include water-soluble films and household care composition, where the films include a polyvinyl alcohol (PVOH) resin blend and optionally one or more additional components such as plasticizers, fillers, surfactants, and other additives. The PVOH resin blend includes a PVOH copolymer including one or more types of anionic monomer units such as a PVOH terpolymer and a PVOH polymer such as another PVOH anionic copolymer or a partially or completely hydrolyzed PVOH homopolymer. When the PVOH copolymer and PVOH polymer are blended in particular proportions and/or selected with regard to various criteria related to physical and chemical film properties, the resulting water-soluble film formed from the PVOH resin blend exhibits substantially improved aqueous dissolution properties, tensile strength properties, and/or tensile modulus properties. | 2016-04-14 |
20160102279 | Articles Comprising Water-Soluble Polyvinyl Alcohol Film with Plasticizer Blend and Related Methods - Disclosed herein are articles that include water-soluble films, where the water-soluble films include a polyvinyl alcohol (PVOH) polymer and a combination of at least three plasticizers. The combination of plasticizers includes dipropylene glycol as a first plasticizer, a sugar alcohol such as sorbitol as a second plasticizer, and a polyol such as glycerin as a third plasticizer. When the PVOH polymer and plasticizers are blended in particular proportions and/or selected with regard to various criteria related to physical and chemical film properties, the resulting water-soluble film formed from the PVOH resin blend exhibits beneficial combinations four) of aged tensile strength, aged melting transition delta elevation, aged adhesion value, and/or resistance to seal peeling, which provide strong film seals that retain their water-solubility characteristics. | 2016-04-14 |
20160102280 | SYSTEM FOR INCUBATING MICROFLUIDIC DROPLETS AND METHOD FOR PRODUCING HOMOGENEOUS INCUBATION CONDITIONS IN A DROPLET INCUBATION UNIT - A system for incubating microfluidic droplets includes a droplet incubator, a gas exchanger and a conveyor. A method provides homogeneous incubation conditions in a droplet incubator by targeted introduction of gases and/or gas mixtures into a carrier fluid. | 2016-04-14 |
20160102281 | HANGING DROP PLATE - A hanging drop plate and a method of cultivating cells or of producing molecular aggregates in at least one liquid volume that adheres to a drop contact area of such a hanging drop plate. The hanging drop plate has a body with a first surface and a second surface that is essentially coplanar to the first surface. The second surface has a drop contact area for adherently receiving a liquid volume. The drop contact area is distinguished from a surrounding area by a relief structure that prevents spreading of the liquid volume on the second surface of the body. The body has at least one conduit that mouths into the drop contact area from the direction of the first surface of the body. A liquid volume is applied to the drop contact area through a communicating conduit. Cells and/or molecules can be introduced into this liquid volume. | 2016-04-14 |
20160102282 | APPARATUS FOR APPLYING ELECTRIC FIELD - An apparatus for applying an electric field includes: a base, on which an internal region is defined, a plurality of electrodes disposed to face each other in parallel in the internal region of the base, and a sample plate disposed between the plurality of electrodes. | 2016-04-14 |
20160102283 | MICROFLUIDIC DEVICE AND SYSTEM FOR PRECISELY CONTROLLING AND ANALYZING SHEAR FORCES IN BLAST-INDUCED TRAUMATIC BRAIN INJURIES - Embodiments of a microfluidic system and method for stimulating a blast shock wave that supports a short and defined laminar flow of a liquid media solution through a microfluidic device such that sheer stress on neural tissue disposed within the microfluidic device is precisely controlled are disclosed. The microfluidic system includes a pneumatic device applies a blast shock wave having a quick rise time across a microfluidic channel of the microfluidic device. The microfluidic device includes an inlet reservoir in fluid flow communication with an outlet reservoir through the microfluidic channel. The inlet and outlet reservoirs are secured to a top structure which is attached to a bottom structure that collectively defines the microfluidic channel with a cover slip that is attached to the underside of the bottom structure. | 2016-04-14 |
20160102284 | ACOUSTIC PERFUSION DEVICES - Acoustic perfusion devices for separating biological cells from other material in a fluid medium are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid medium is being drawn. | 2016-04-14 |
20160102285 | METHODS AND APPARATUS FOR CONTINUOUS ENZYMATIC HYDROLYSIS OF PRETREATED BIOMASS - Some variations provide an apparatus for enzymatically hydrolyzing pretreated lignocellulosic biomass, including at least one clarifying vessel comprising: an inlet well, disposed with walls at or near the top of the clarifying vessel, configured for continuously feeding pretreated lignocellulosic biomass; overflow weirs to allow liquid-phase hydrolysate to be continuously recovered from the clarifying vessel; and a controllable bottom outlet to allow a solid phase to be continuously or periodically recovered from the clarifying vessel. In certain embodiments, the clarifying vessel is an existing recausticizing clarifier in a pulp and paper mill. Other variations provide a method of enzymatically hydrolyzing pretreated lignocellulosic biomass, comprising: introducing pretreated lignocellulosic biomass to a clarifying vessel in the presence of cellulase enzymes, to hydrolyze the cellulose to a liquid-phase hydrolysate; separating, by sedimentation, the hydrolysate from the lignin; and recovering the hydrolysate from overflow weirs of the clarifying vessel. | 2016-04-14 |
20160102286 | Methods For The Cryopreservation Of Mammalian Cells - Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells. | 2016-04-14 |
20160102287 | Method and Apparatus for Growing Microbial Cultures that Require Gaseous Electron Donors, Electron Acceptors, Carbon Sources, or Other Nutrients - Compositions and methods and apparatus for growth and maintenance of microorganisms and/or bioprocesses using one or more gases as electron donors, electron acceptors, carbon sources, or other nutrients, and for a bioprocess that converts hydrogen and carbon dioxide, or syngas, or producer gas into lipid products, bio-based oils, or other biochemical products. | 2016-04-14 |
20160102288 | EFFICIENT STEM CELL DELIVERY INTO BIOMATERIALS USING CAPILLARY DRIVEN ENCAPSULATION - Efficient stem cell delivery into biomaterials using capillary driven encapsulation are disclosed herein where stem/progenitor and/or tissue specific cells are rapidly and efficiently seeded via capillary driven encapsulation into a porous scaffold for cell deliver in the skin or any other organ. The rapid capillary force approach maximizes both seeding time and efficiency by combining hydrophobic, entropic and capillary forces to promote active, ‘bottom-up’ cell engraftment. This methodology uses micro domain patterned biopolymers in a porous dry gel to generate capillary pressure to move a viscous stem cell mix from a hydrophobic reservoir into the polymer matrix to promote active cell seeding within the entire gel volume. | 2016-04-14 |
20160102289 | GENERATION OF KERATINOCYTES FROM PLURIPOTENT STEM CELLS AND MAINTENANCE OF KERATINOCYTE CULTURES - Provided herein are methods for the generation of functional keratinocyte stem cells that are differentiated directly from human ESCs/iPSCs in a chemically defined serum-free cell culture system, as well as cells derived therefrom and methods of use thereof. Also provided are methods for culturing primary keratinocytes. | 2016-04-14 |
20160102290 | IDENTIFICATION AND ISOLATION OF HUMAN CORNEAL ENDOTHELIAL CELLS (HCECS) - The present invention provides methods for the identification, isolation and/or enrichment of human corneal endothelial cells (HCECs). In some embodiments, the method comprises a positive selection process in which a cell population containing human corneal cells is contacted with a positive affinity reagent that selectively binds to HCECs relative to cells other than HCECs (e.g., corneal keratocytes, etc.) in the population and/or a negative selection process in which a cell population containing HCECs is contacted with a negative affinity reagent that selectively binds to cells other than HCECs in the population relative to HCECs. The present invention also provides reagents and kits for the identification, isolation and/or enrichment of HCECs as well as compositions that are enriched in HCECs. | 2016-04-14 |
20160102291 | Dendritic Cell Compositions and Methods - Methods are provided for the production of dendritic cells from monocytes that have been incubated at a temperature of 1° C.-34° C. for a period of approximately 6 to 96 hours from the time they are isolated from a subject. After the incubation period, the monocytes can then be induced to differentiate into dendritic cells. Mature dendritic cells made by the methods of the invention have increased levels of one or more of CD80, CD83, CD86, MHC class I molecules, or MHC class II molecules as compared to mature dendritic cells prepared from monocytes that have not been held at 1° C.-34° C. for at least 6 hours from the time they were isolated from a subject. Dendritic cells made by the methods of the invention are useful for the preparation of vaccines and for the stimulation of T cells. | 2016-04-14 |
20160102292 | ISOLATION AND CULTIVATION OF STEM/PROGENITOR CELLS FROM THE AMNIOTIC MEMBRANE OF UMBILICAL CORD AND USES OF CELLS DIFFERENTIATED THEREFROM - The present invention relates to the generation of a chondrocyte using mesenchymal stem/progenitor cells obtained from the amniotic membrane of umbilical cord and therapeutic uses of such chondrocytes. | 2016-04-14 |
20160102293 | DEVICE AND METHOD OF 3-DIMENSIONALLY GENERATING IN VITRO BLOOD VESSELS - Apparatuses, systems, and methods for generating concentration gradients of soluble molecules are disclosed herein. Devices and methods for generating in vitro blood vessels are also disclosed. | 2016-04-14 |
20160102294 | ENDOCARDIUM-DERIVED ADULT STEM CELLS AND METHOD FOR PRODUCING SAME - The present invention relates to endocardium-derived adult stem cells obtained by culturing peripheral blood mononuclear cells (PBMCs) separated from peripheral blood, and a cell therapeutic agent for treating cardiovascular diseases containing the same as an active ingredient. The adult stem cells, according to the present invention, have an origin that is the endocardium and strong blood vessel formation, and is thus remarkably useful for treating cardiovascular diseases such as ischemia, myocardial infarction, and the like. | 2016-04-14 |
20160102295 | MODIFIED ADENOVIRUS HEXON PROTEIN AND USES THEREOF - The present invention provides a method of altering the specificity of an adenovirus vector. The method involves providing an adenovirus having a capsid with a modified adenovirus hexon protein. The modified adenovirus has a capsid comprising a hexon protein with a deletion in hypervariable region 1 and/or hypervariable region 4 of the hexon and an insert of an exogenous molecule therein. | 2016-04-14 |
20160102296 | INFECTIOUS HEPATITIS E VIRUS GENOTYPE 3 RECOMBINANTS - The invention relates to the discovery of an HEV strain from a chronically infected patient. The virus grow unusually well in numerous cell cultures. Thus, the invention provides cell cultures, vectors, and vaccine compositions based on the virus. | 2016-04-14 |
20160102297 | RESTRICTIVE INVERTED TERMINAL REPEATS FOR VIRAL VECTORS - This invention relates to modified parvovirus inverted terminal repeats (ITRs) that do not functionally interact with wild-type large Rep proteins, synthetic Rep proteins that functionally interact with the modified ITRs, and methods of using the same for delivery of nucleic acids to a cell or a subject. The modifications provide a novel Rep-ITR interaction that limits vector mobilization, increasing the safety of viral vectors. | 2016-04-14 |
20160102298 | N-TERMINALLY TRUNCATED GLYCOSYLTRANSFERASES - The present disclosure is directed to glycosyltransferase variants having N-terminal truncation deletions. Contrary to previous findings certain truncations comprising the conserved amino acid motif (“QVWxKDS”) were found to be compatible with glycosyltransferase enzymatic activity, particularly in a human sialyltransferase (hST6Gal-I). Thus, disclosed are variants of mammalian glycosyltransferase, nucleic acids encoding the same, methods and means for recombinantly producing the variants of mammalian glycosyltransferase and use thereof, particularly for sialylating terminal acceptor groups of glycan moieties being part of glycoproteins such as immunoglobulins. | 2016-04-14 |
20160102299 | POLYPEPTIDES ENCODING MUTATED MANNANASES WITH IMPROVED CATALYTIC EFFICIENCY - A polypeptide which is a mutated mannanase, whose sequence is derived from a native mannanase of the filamentous ascomycete coprophile fungus | 2016-04-14 |
20160102300 | IMMOBILIZED PROLINE-SPECIFIC ENDOPROTEASE - The present invention relates to immobilized proline-specific endoprotease, wherein the proline-specific endoprotease is immobilized on a carrier comprising methacrylate which has been functionalized with amino dimethylene, and wherein the carrier has a particle size range of 100 to 400 μm. The invention also relates to a process for producing beer comprising the steps of preparing a mash, fermenting the beer, and stabilizing the beer, wherein the beer is incubated with the immobilized proline-specific endoprotease. | 2016-04-14 |
20160102301 | PROTEIN, METHOD FOR MANUFACTURING SAME, AND METHOD FOR EVALUATING PROTEIN ACTIVITY - The present invention relates to a method for producing a protein, comprising an inspection process, wherein the inspection process comprises: a step of approximating an infrared absorption band derived from a protein appearing around 1500 to 1600 cm | 2016-04-14 |
20160102302 | COMPOSITE MATERIAL AND METHOD OF MANUFACTURING COMPOSITE MATERIAL - A composite material includes: an apatite crystal in the form of a tube; and a functional component accommodated in the apatite crystal tube and constituted by a material having physical properties different from those of the apatite crystal. The apatite crystal may be a monocrystal given by the general formula M | 2016-04-14 |
20160102303 | METHOD OF ISOLATING NUCLEIC ACID - Disclosed herein is a method for isolating a nucleic acid from a sample. The method includes contacting the sample with boron carbide under conditions sufficient to form a boron carbide-nucleic acid complex. The complex is separated from the sample. | 2016-04-14 |
20160102304 | METHODS AND COMPOSITIONS FOR ISOLATING SMALL RNA MOLECULES - The present invention concerns the use of methods and compositions for the isolation of small RNA molecules (100 nucleotides or fewer), such as microRNA and siRNA molecules. Such molecules are routinely lost in commonly used isolation procedures and therefore the present invention allows for a much higher level of enrichment or isolation of these small RNA molecules. | 2016-04-14 |
20160102305 | POLYNUCLEOTIDE CAPTURE MATERIALS, AND METHODS OF USING SAME - Methods for processing polynucleotide-containing biological samples, and materials for capturing polynucleotide molecules such as RNA and/or DNA from such samples. The RNA and/or DNA is captured by polyamindoamine (PAMAM (Generation 0)) bound to a surface, such as the surface of magnetic particles. The methods and materials have high efficiency of binding RNA and of DNA, and of release, and thereby permit quantitative determinations. | 2016-04-14 |
20160102306 | High Fidelity Restriction Endonucleases - Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions includes restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor. | 2016-04-14 |
20160102307 | OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA - Provided are LMNA-targeted antisense oligonucleotides for reducing expression of one or more aberrantly spliced LMNA mRNA isoforms that encode progerin. | 2016-04-14 |
20160102308 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR OXIDATIVE STRESS AND RETINITIS PIGMENTOSA - Oxidative damage contributes to cone cell death in retinitis pigmentosa and death of rods, cones, and retinal pigmented epithelial (RPE) cells in ocular oxidative stress related diseases including age-related macular degeneration and retinitis pigmentosa. Oral antioxidants may provide modest benefits, but more efficient ways of preventing oxidative damage are needed. Compositions and methods are provided herein for the prevention, amelioration, and/or treatment of early or late stage ocular disease by increasing the expression or activity of one or more peroxidases in cells of the eye, particularly retinal cells, and further optionally increasing the expression or activity of one or more superoxide dismuatases in the same cells. | 2016-04-14 |
20160102309 | IN VIVO PRODUCTION OF SMALL INTERFERING RNAS THAT MEDIATE GENE SILENCING - The invention provides engineered RNA precursors that when expressed in a cell are processed by the cell to produce targeted small interfering RNAs (siRNAs) that selectively silence targeted genes (by cleaving specific mRNAs) using the cell's own RNA interference (RNAi) pathway. By introducing nucleic acid molecules that encode these engineered RNA precursors into cells in vivo with appropriate regulatory sequences, expression of the engineered RNA precursors can be selectively controlled both temporally and spatially, i.e., at particular times and/or in particular tissues, organs, or cells. | 2016-04-14 |
20160102310 | miR-96-5p INHIBITOR AND A SCREENING METHOD FOR THE INHIBITOR - The present invention provides novel medical means to facilitate glutathione (GSH) synthesis in the brain. These means are miR-96-5p inhibitor increasing GSH expression in the brain and a pharmaceutical composition comprising the miR-96-5p inhibitor and having a preventive and/or therapeutic performance to a disease caused by decrease of GSH amount or depression of GSH activity. | 2016-04-14 |
20160102311 | Protection Against Ionizing Radiation and Chemotherapy Toxicity via Latexin Regulation - The present invention relates to methods for protecting against damage caused by radiation and/or chemotherapy, and methods for treating bone marrow damage by reducing/inhibiting Latexin expression and/or Latexin activity. The methods comprise administering to a subject in need thereof a pharmaceutical composition comprising an antagonist that reduces expression and/or activity of latexin, wherein latexin is a latexin polynucleotide variant and/or a latexin polypeptide variant that binds to the antagonist. | 2016-04-14 |
20160102312 | Compositions And Methods For Inhibiting Expression Of The HAMP Gene - The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the HAMP gene (HAMP gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of the HAMP gene. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier; methods for treating diseases caused by HAMP gene expression and the expression of the HAMP gene using the pharmaceutical composition. | 2016-04-14 |
20160102313 | DOUBLE STRANDED RNA COMPOUNDS TO RHOA AND USE THEREOF - The present invention relates to compounds, pharmaceutical compositions comprising same, methods of use thereof and kits for the down-regulation of RhoA gene. The compounds, compositions, methods and kits are useful in the treatment of subjects suffering from diseases or conditions and or symptoms associated with diseases or conditions in which RhoA expression has adverse consequences and for conferring neuroprotection. | 2016-04-14 |
20160102314 | EXOGENOUS TERMINATORS FOR CONTROLLING FUNGAL GENE EXPRESSION - Provided herein are exogenous terminator sequences for use in fungi cell transcriptional termination. | 2016-04-14 |
20160102315 | Methods for producing polypeptides in enzyme-deficient mutants of fusarium venentatum - The present invention relates to methods of producing a polypeptide, comprising: (a) cultivating a mutant of a parent | 2016-04-14 |
20160102316 | STRESS TOLERANT PLANTS - The invention relates to transgenic plants and methods for modulating abscisic acid (ABA) perception and signal transduction in plants. The plants fmd use in increasing yield in plants, particularly under abiotic stress. | 2016-04-14 |
20160102317 | PLANTS HAVING INCREASED TOLERANCE TO HERBICIDES - The present invention refers to a method for controlling undesired vegetation at a plant cultivation site, the method comprising the steps of providing, at said site, a plant that comprises at least one nucleic acid comprising a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a HPPD-inhibiting herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a HPPD-inhibiting herbicide, preferably a bicycloarylcarboxamide, applying to said site an effective amount of said herbicide. The invention further refers to plants comprising mut-HPPD, and methods of obtaining such plants. | 2016-04-14 |
20160102318 | MELON PLANTS WITH IMPROVED DISEASE TOLERANCE - The present disclosure provides melon plants exhibiting tolerance to cucurbit yellow stunt disorder virus (CYSDV) and lacking negative traits associated with CYSDV tolerance such as increased fruit size and reduced fruit set. Such plants may comprise novel introgressed genomic regions associated with disease tolerance. In certain aspects, compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease tolerance phenotype are provided. | 2016-04-14 |
20160102319 | CMP-ACETYLNEURAMINIC ACID HYDROXYLASE TARGETING VECTOR, TRANSGENIC ANIMAL FOR XENOTRANSPLANTATION INTRODUCED WITH THE VECTOR, AND METHOD OF MANUFACTURING THE SAME - There is provided a CMP-acetylneuraminic acid hydroxylase targeting vector, a transgenic animal for xenotransplantation introduced with the vector, and a method of manufacturing the same. The targeting vector and the cell line for transformation prepared by the present invention can be used for the efficient production of cloned pigs for xenotransplantation by the complex regulation of the expression of the genes involved in the immunological rejection responses. | 2016-04-14 |
20160102320 | ADENOVIRAL VECTOR ENCODING HUMAN ATONAL HOMOLOG-1 (HATH1) - The invention is directed to a replication-deficient adenoviral vector comprising a nucleic acid sequence encoding a human atonal homolog-1 (Hath1) protein operably linked to a human glial fibrillary acidic protein (GFAP) promoter. The invention also is directed to a composition and method utilizing the adenoviral vector to generate sensory cells in the inner ear of a human. | 2016-04-14 |
20160102321 | HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION - The present invention provides novel mRNA elements capable of forming hairpin, double-stranded RNA structures independent of other non-coding RNAs. These mRNAs are stably expressed, lack polyadenylation tails, and allow minimal protein translation except when in the presence of specific proteins. Also provided, are compositions and kits comprising the mRNA element, as well as methods for its use in the regulation of protein translation. Advantageously, the disclosed elements represent a novel tool useful in regulating the expression of a wide variety of proteins of interest. | 2016-04-14 |
20160102322 | CRISPR OLIGONUCLEOTIDES AND GENE EDITING - The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR reagents and the use of such reagents. | 2016-04-14 |
20160102323 | A LAGLIDADG HOMING ENDONUCLEASE CLEAVING THE C-C CHEMOKINE RECEPTOR TYPE-5 (CCR5) GENE AND USES THEREOF - Disclosed herein are compositions for inactivating the human CCR5 gene comprising engineered LAGLIDADG homing endonucleases (LHEs) and their derivatives, particularly derived from members of the \-OnuI subfamily of LHE. Polynucleotides encoding such endonucleases, vectors comprising said polynucleotides, cells comprising or having been treated with such endonucleases, and therapeutic compositions deriving therefrom are also provided. | 2016-04-14 |
20160102324 | NEW COMPACT SCAFFOLD OF CAS9 IN THE TYPE II CRISPR SYSTEM - The present invention is in the field of CRISPR-Cas system for genome targeting. The present invention relates to new engineered Cas9 scaffolds and uses thereof. More particularly, the present invention relates to methods for genome targeting, cell engineering and therapeutic application. The present invention also relates to vectors, compositions and kits in which the new Cas9 scaffolds of the present invention are used. | 2016-04-14 |
20160102325 | Method for Storing Gaseous Hydrogen Through Producing Methanoate (Formate) - The present invention relates to a method for storing gaseous hydrogen, comprising the steps of producing methanoate (formate) through contacting gaseous hydrogen with carbon dioxide in the presence of a hydrogen dependent carbondioxide reductase (HDCR), and thereby storing of said gaseous hydrogen. The HDCR and/or its complex is preferably derived from | 2016-04-14 |