16th week of 2015 patent applcation highlights part 33 |
Patent application number | Title | Published |
20150104295 | Piezoelectric Damper System for an Axial Turbomachine Rotor - The present application relates to a rotor of a compressor or axial turbomachine comprising a vibration-damping system equipped with piezoelectric transducers distributed circularly and connected to dissipative resonant electric circuits. The circuits are closed and are equipped with a resistor and a coil. The piezoelectric transducers are divided into two sets of alternated transducers, each set being connected to a passive RLC circuit. In order to ensure a pooling of capacitances and currents thereof, the piezoelectric transducers are connected in parallel. During operation, the rotor is subjected to a turning excitation and is likely to vibrate and to deform in accordance with a modal shape with diameters with orthogonal deformation waves. The number of transducers is equal to the quadruple of the number of diameters of the mode, so as to be able to utilize the symmetrical character of this mode with diameters. The grouping of the piezoelectric transducers that deform in the same way makes it possible to damp the piezoelectric transducers with identical means thus pooled. | 2015-04-16 |
20150104296 | VARIABLE GEOMETRY TURBOCHARGER - In a variable geometry turbocharger including a variable nozzle mechanism, an object is to enhance safety upon malfunction of the variable nozzle mechanism as well as to improve accuracy in the control of the variable nozzle mechanism by applying a moment that acts on the nozzle vanes in an opening direction securely and stably. A variable geometry turbocharger includes a plurality of nozzle vanes | 2015-04-16 |
20150104297 | TURBOCHARGER - A turbocharger has a casing system which houses a centrifugal impeller connected to a turbine by a shaft. The casing system includes an insert casing which forms a duct for feeding air to and through the impeller, and a volute casing which forms a volute for receiving compressed air from the impeller, the insert casing inserting into the volute casing. The casing system further includes a main casing which forms a housing for the shaft and for the shaft-side end of the impeller. The impeller includes a hub which has a radially outer annular rim, and has front and rear faces which converge towards the rim from respectively the inlet side and the shaft side of the hub. The impeller further includes a plurality of circumferentially arranged vanes on the front face of the hub. The impeller further includes a seal formation formed on the rear face at the rim. | 2015-04-16 |
20150104298 | TIP TREATMENT BARS IN A GAS TURBINE ENGINE - There is presented a casing arrangement for a gas turbine engine. The casing arrangement includes a plurality of tip treatment bars extending between a pair of spaced-apart annular supports, with each tip treatment bar being elongate and supported at each end by a respective support such that each end of the bar is received within an opening formed in the respective support. At least the ends of each tip treatment bar are tapered in transverse cross-section so as to have a wedge-shaped profile, and the openings in the supports have a complementary tapered shape for receipt and retention of the bar ends therein. | 2015-04-16 |
20150104299 | TURBINE ENGINE VANE WITH ASYMMETRICAL PROFILE - The invention relates to a turbine engine vane comprising a main body made of composite material, a leading edge, a trailing edge, and at least one metal structural reinforcement, the structural reinforcement comprising a junction surface portion connected to the main body, the structural reinforcement extending between the junction surface portion and one of the leading or trailing edges, the vane being characterized in that the profile of the junction surface portion of the structural reinforcement has a camber less than 30%. | 2015-04-16 |
20150104300 | TURBOCHARGER - A turbocharger for an engine includes a compressor impeller, a turbine wheel, a turbine housing, a cover, and a flow passage switching valve. The impeller is for compression of intake air. The wheel drives the impeller. The housing includes first and second exhaust scrolls independently of each other, and a flow passage switching hole. The first and second exhaust scrolls swirl exhaust gas which is discharged from the engine and blow the swirled exhaust gas toward the wheel. The hole guides exhaust gas into the second exhaust scroll. The cover is provided separately from the housing. The valve opens or closes the hole, and includes a movable part having a rotatable shaft and a valving element. The movable part is attached to the cover. The cover is press-fitted to the housing, so that the valve is attached to the turbocharger. | 2015-04-16 |
20150104301 | MOTOR HOUSING FOR A CABIN AIR COMPRESSOR - motor housing for a cabin air compressor includes a central body portion having a center wall thickness and an internal cavity that is configured to receive an electric motor, a first end portion having a second internal cavity that is configured to receive a first end winding of the stator, and a second end portion having a third internal cavity configured to receive a second end winding of the stator. A ratio of a wall thickness of either of the first or the second end portions to the motor wall thickness is at least greater than 1.68 to 1. | 2015-04-16 |
20150104302 | RAM AIR FAN HOUSING - A fan housing of a ram air fan assembly is provided including a flange having at least one tab. The at least one tab includes a first portion extending generally perpendicularly from the flange and a second portion extending generally parallel to the flange. A notch is formed by an inclined surface and a curved surface at an intersection between the first portion and the second portion. The second portion is elongated and extends about 0.020 inches beyond a front surface of the first portion. | 2015-04-16 |
20150104303 | Turbocharger - A turbocharger for an internal combustion engine having a housing, an impeller arranged in the housing interior having an impeller shaft and being mounted in a bearing block, and an intermediate element between the impeller and the bearing block. The housing includes at least one flow channel for feeding or discharging a fluid to or from the impeller, and the intermediate element includes a wall section that delimits a least a section of at least one of the flow channels. | 2015-04-16 |
20150104304 | MOUNTING STRUCTURE OF COOLING-FAN - A mounting structure of a cooling-fan mounted in an opening formed on a Front End Module (FEM) carrier may include a locking guide fixed to the opening and along a longitudinal direction of which a guide hole is formed, a link bar along a longitudinal direction of which a sliding hole is pierced and one end of which is connected rotatively to the FEM carrier, a first pin that is slid through the respective guide hole and sliding hole and connects the link bar and the locking guide, a second pin, one end of which is connected slidingly to the sliding hole, and a motor connected to the other end of the second pin to rotate the second pin. The cooling-fan is connected to the first pin and slid through the opening by link-movement of the first pin, the second pin and the link bar. | 2015-04-16 |
20150104305 | FAN ASSEMBLY AND FASTENER THEREOF - A fastener includes a main body and a bending body. The main body includes a protrusion section and an extension section. The extension section is connected with the protrusion section. The bending body is connected with the extension section of the main body. The bending body includes a first plate and a second plate. The first plate is connected with the extension section. The second plate is connected with the first plate. An angle is formed between the first plate and the second plate. The second plate has a first surface and a second surface which is opposite to the first surface. The first surface faces toward the main body, and the second plate has a first rib protruding from the second surface. | 2015-04-16 |
20150104306 | FAN CASING ARRANGEMENT FOR A GAS TURBINE ENGINE AND RELATED METHOD - A fan casing arrangement for a gas turbine engine having a propulsive fan, the arrangement having a fan case and a fan track liner and being configured to circumscribe the fan, wherein the fan track liner is provided around the inside of fan case so as to adopt a radial position between the fan and the fan case. The fan track liner includes an elongate member which is helically-wound against the inside of the fan case in a plurality of turns. A method of installing a fan track liner in a fan casing arrangement for a gas turbine engine having a propulsive fan, the method involving: providing a fan case to circumscribe the fan, providing a flexible and elongate liner member, and helically winding the liner member against the inside of the fan case in a plurality of turns to define at least part of the fan track liner. | 2015-04-16 |
20150104307 | Actuation System for an Active Blade Element of a Rotor Blade - One example of an actuation system for an active blade element of a rotor blade includes an actuator system coupled to a linear transmission system. The actuator system attaches to a structure within a rotor blade and provides a linear motion in a direction that is spanwise to the rotor blade. The linear transmission system is coupled with the actuator system and to an active blade element attached to the rotor blade. The linear transmission system receives the linear motion provided by the actuator system, and responsively provides at least a partial rotation of the active blade element about an axis of the linear transmission system which is in the direction that is substantially parallel to the spanwise axis of the rotor blade. | 2015-04-16 |
20150104308 | BRUSH DESIGN FOR PROPELLER DEICING SYSTEM - A propeller assembly is provided including a plurality of blades arranged in diametrically opposed pairs. Each of the plurality of blades has an electrical deicer located thereon. The propeller assembly also includes a slip ring, and a stationary brush arranged in contact with the slip ring. The brush is configured to transfer electrical power from a power source to the slip ring. A movable portion of an actuator is configured to sequentially couple the electrical deicers of each pair of blades to the rotating slip ring. | 2015-04-16 |
20150104309 | AIRCRAFT CONTROL SYSTEM AND METHOD - An aircraft control system includes a co-axial, counter-rotating propeller shaft assembly. Also included is a first rotor operatively coupled to the propeller shaft assembly, the first rotor having a first plurality of blades mounted thereto, wherein the first plurality of blades are disposed at a substantially identical nominal pitch during rotation of the first rotor. Further included is a second rotor operatively coupled to the propeller shaft assembly, the second rotor having a second plurality of blades mounted thereto, wherein a pitch of the second plurality of blades is configured to cyclically change during rotation of the second rotor. | 2015-04-16 |
20150104310 | FREQUENCY RESPONSE AND HEALTH TRACKER FOR A SYNTHETIC JET GENERATOR - A jet generator is controlled by providing an input signal at a variable frequency to the jet generator and to a simulated electrical load of the jet generator, measuring a difference in signals between the jet generator and the simulated electrical load to identify an optimum flow of a jet generated by the jet generator, and tuning the frequency of the input signal to maintain the jet at the optimum flow. | 2015-04-16 |
20150104311 | EXTERNALLY PROGRAMMABLE FAN - A fan comprising: (a) an impeller, (b) a motor connected to the impeller so that during operation the motor drives the impeller to move a fluid; (c) an instrumentation assembly that includes one or more components for controlling one or more operations of the fan; (d) an interface in communication with the instrumentation assembly; wherein the interface is configured so that one or more programs, one or more signals, or both can be input into the fan after a final assembly of the fan so that the fan can be configured to perform a desired function at the time of installation into a final product, reconfigured for a different purpose than originally programmed, or both. | 2015-04-16 |
20150104312 | TRILLIUM WIND TURBINE - A trillium wind turbine can have a plurality of blades. Together, the swept-back, complexly-curved blades can be attached to an electricity-generating nacelle. Each blade has a main blade, and a trailing edge blade, and can optionally have a diversion blade. Wind is directed down the length of the blade and exits the tip. The main blade resembles a portion of a cylinder in form, the cylinder being twisted to change the angle of attack, thereby adding more lift throughout the length of the blade. The trailing edge and diversion blades are pitched relative to the wind and produce lift. Additionally, wind hitting the diversion blade is diverted behind the blade. Because the surface area and volume of the blade are larger near the base and smaller at the tip, the air traveling along the blade increases in velocity producing more thrust/lift. The turbine also automatically faces into the wind without the need for sensors or positioning motors. | 2015-04-16 |
20150104313 | BRUSH DESIGN FOR PROPELLER DEICING SYSTEM - A brush configured to engage a rotating component to transfer an electrical signal and/or power is provided including a body formed from a core material. A coating material is disposed over a portion of the body configured to contact the rotating component. A contact area between the brush and the rotating component increases as the coating material wears. | 2015-04-16 |
20150104314 | ADAPTIVELY-TWISTABLE BLADE, AND AN AIRCRAFT INCLUDING SUCH A BLADE | 2015-04-16 |
20150104315 | Fan Blade Root Integrated Sealing Solution - A gas turbine engine, a fan section for a gas turbine engine, and a method for assembling a fan section of a gas turbine engine are disclosed. The fan section may include a fan hub having a slot, a spinner having a castellated spinner seal, a fan blade including an airfoil extending from a root to a tip, wherein the airfoil has a leading edge and the root is received in the slot, and a platform secured to the fan hub and arranged between adjacent fan blades. The fan section may further include a flap seal having a base secured to a side of the platform, and a flap integral with and extending from the base portion and canted toward the root and engaging the blade, the seal trimmed back from the leading edge of the airfoil. | 2015-04-16 |
20150104316 | TURBINE BLADES - A turbomachine apparatus for driving a compressor is disclosed. The turbomachine apparatus contains at least one rotor stage and at least one retaining element. The at least one rotor stage contains a plurality of blades and is configured to rotate about an axis. The at least one retaining element is configured to retain the at least one rotor stage with the blades thereof at least partly or wholly in radial compression during rotation thereof. | 2015-04-16 |
20150104317 | REDUCED STRESS SUPERBACK WHEEL - Turbocharger turbine wheels are designed to accelerate rapidly and to rotate at very high RPM. A turbine wheel is provided with improved low cycle fatigue resistance. The wheel can be balanced by conventional methods. | 2015-04-16 |
20150104318 | TURBINE ROTOR FOR AN EXHAUST-GAS TURBINE AND METHOD FOR PRODUCING THE TURBINE ROTOR - A turbine rotor as a turbine impeller made of a high-temperature-resistant metal alloy and a rotor shaft made of steel. The impeller hub and the rotor shaft end are connected together in a metallurgically bonded manner by way of a brazed connection. Between the end faces of the impeller hub and of the rotor shaft end, a brazing gap filled with brazing alloy is arranged concentrically with the rotation axis of the turbine rotor. A width of the soldering gap is previously determined by circularly peripheral removal of material on the end face of the impeller hub or the end face of the rotor shaft end, and the brazing connection is produced by an electron beam soldering process. | 2015-04-16 |
20150104319 | TURBINE WITH BUCKET FIXING MEANS - Provided is a turbine including a rotor wheel including a plurality of dovetail grooves and a insertion groove, the insertion groove including a first catching groove; a plurality of first buckets, each of the plurality of first buckets including a vane, a platform provided at a first end portion of the vane, and a dovetail provided at the platform and having a shape corresponding to the dovetail groove; a second bucket including a vane, a platform provided at a first end portion of the vane, and a protrusion portion and configured to be inserted into the insertion groove, the protrusion portion including a second catching groove; and a fixing member configured to be inserted into each of the first and second catching grooves, the fixing member configured to restrict radial movement of the second bucket. | 2015-04-16 |
20150104320 | TURBINE WITH BUCKET FIXING MEANS - There is provided a turbine including a rotor wheel including a plurality of dovetail grooves and at least one insertion groove, the dovetail grooves and the insertion groove arranged in a circumferential direction of the rotor wheel; a plurality of first buckets, each of the first buckets including a vane, a platform provided at a first end portion of the vane, and a dovetail provided at the platform and having a shape corresponding to a corresponding dovetail groove; at least one second bucket including a vane, a platform provided at a first end portion of the vane, and at least one protrusion portion provided at the platform and configured to be inserted into a corresponding insertion groove of the insertion groove; and a fixing member configured to be inserted through the protrusion portion and the rotor wheel and configured to restrict radial movement of the second bucket. | 2015-04-16 |
20150104321 | WIND SPINNER - A wind spinner includes a body, at least one rod attached to the body for rotation about a blade axis, at least two blades disposed at opposing ends of the rod, forming at least one pair of blades, and at least one blade support disposed within each blade. The at least one blade support includes a central portion disposable on the at least one rod. The central portion is attached to at least one wing portion that extends outwardly therefrom to provide internal support to the blade. In addition, the blades are angled at a blade angle and at a position on the at least one rod such that wind passing thereover causes the at least one pair of blades to rotate about the blade axis. | 2015-04-16 |
20150104322 | THERMAL MANAGEMENT ARTICLE AND METHOD OF FORMING THE SAME, AND METHOD OF THERMAL MANAGEMENT OF A SUBSTRATE - A thermal management article, a method for forming a thermal management article and a thermal management method are disclosed. Forming a thermal management article includes forming a duct adapted to be inserted into a groove on the surface of a substrate, and attaching the duct to the groove so that the top outer surface of the duct is substantially flush with the surface of the substrate. Thermal management of a substrate includes transporting a fluid through the duct of a thermal management article to alter the temperature of the substrate. | 2015-04-16 |
20150104323 | METHOD FOR CREATING A METAL REINFORCEMENT WITH INSERT FOR PROTECTING A LEADING EDGE MADE OF COMPOSITE - A method for producing a metal reinforcement for protecting a leading edge of a compressor blade of composite, including: creating a core that has a shape of an internal cavity of the reinforcement; creating an insert made of an alloy of a hardness greater than that of the reinforcement; shaping sheet metal by stamping with the creation, upstream of the core, a cavity between the metal sheets, which cavity is configured to accept the insert, positioning the sheets around the core with the insert placed in the cavity and securing the assembly together; creating a vacuum and closing the assembly by welding; consolidation by hot isostatic pressing; cutting the assembly to extract the core and separate the reinforcement; creating an external profile of the reinforcement by a final machining operation that reveals a material of the insert. | 2015-04-16 |
20150104324 | FAN ROTOR BLADE OF AIRCRAFT JET ENGINE - A fan rotor blade includes a blade body made from a composite material of a resin and fibers, and having a pressure surface and a suction surface. A dovetail capable of being fitted into a fitting groove in a fan disk is provided in a base end of the blade body. The blade body is provided with a sheath. The sheath is more rigid than the blade body and is fixed to the blade body in a state where the sheath covers a leading edge portion of the blade body and the vicinity thereof. The sheath extends in the longitudinal direction of the blade body from a blade root side to a tip end side of the blade body, and a base end portion of the sheath located on the blade root side of the blade body extends to the dovetail. | 2015-04-16 |
20150104325 | FAN ROTOR BLADE OF AIRCRAFT JET ENGINE - A fan rotor blade includes a blade body made from a composite material of a resin and fibers, and having a pressure surface facing one side in a rotation direction and a suction surface facing the other side in the rotation direction. The blade body is provided with a sheath which is more rigid than the blade body and is fixed to the blade body in a state where the sheath covers a leading edge portion of the blade body, which is located on an upstream side in the direction of intake of external air, and the vicinity thereof. A tip end portion of the sheath extends from the leading edge portion side of the blade body to a trailing edge portion side of the blade body. An end portion of the tip end portion of the sheath is flush with the trailing edge portion of the blade body. | 2015-04-16 |
20150104326 | TURBINE ROTOR BLADES WITH IMPROVED TIP PORTION COOLING HOLES - A turbine rotor blade is provided for a turbine section of an engine. The turbine rotor blade includes a platform and an airfoil extending from the platform into a mainstream gas path of the turbine section. The airfoil includes a first side wall; a second side wall joined to the first side wall at a leading edge and a trailing edge; a tip cap extending between the first side wall and the second side wall; a first parapet wall extending from the first side wall; and a first cooling hole through the tip cap and the first parapet wall configured to deliver cooling air. The first cooling hole has a closed channel section and an open channel section. The open channel section forms a slot. | 2015-04-16 |
20150104327 | TURBINE ROTOR BLADES WITH TIP PORTION PARAPET WALL CAVITIES - In accordance with an exemplary embodiment, a turbine rotor blade is provided for a turbine section of an engine. The turbine rotor blade includes a platform and an airfoil extending from the platform into a mainstream gas path of the turbine section. The airfoil includes a first side wall; a second side wall joined to the first side wall at a leading edge and a trailing edge; a tip cap extending between the first side wall and the second side wall; a first parapet wall extending from the first side wall; a first parapet wall cavity formed at least partially within the first parapet wall; and a first cooling hole extending between the first parapet wall cavity and a first surface of the first parapet wall such that cooling air flows through the first parapet wall cavity, through the first cooling hole, and out of the first parapet wall. | 2015-04-16 |
20150104328 | SUBSEA PUMPING APPARATUSES AND RELATED METHODS - This disclosure includes subsea pumping apparatuses and related methods. Some apparatuses include one or more subsea pumps, each having an inlet and an outlet, and one or more motors, each configured to actuate at least one pump to communicate a hydraulic fluid from the inlet to the outlet, where the subsea pumping apparatus is configured to be in fluid communication with a hydraulically actuated device of a blowout preventer. Some subsea pumping apparatuses include one or more of: a desalination system configured to produce at least a portion of the hydraulic fluid; one or more valves, each configured to selectively route hydraulic fluid from an outlet of a pump to, for example, a subsea environment, a reservoir, and/or the inlet of the pump; and a reservoir configured to store at least a portion of the hydraulic fluid. Some apparatuses are configured to be directly coupled to the hydraulically actuated device. | 2015-04-16 |
20150104329 | PERISTALTIC PUMP SYSTEMS AND METHODS - Staged peristaltic pump systems and related methods are disclosed. A system may be configured such that the working fluid pressure differential across any individual stage of the system is smaller than the pressure across the entire system. In some embodiments certain components of each stage may be sealed from fluid communication with an external environment, though working fluid may be configured to cross the boundary of the seal. In some embodiments, stages may be pressurized with respect to an external environment. | 2015-04-16 |
20150104330 | PERISTALTIC PUMP SYSTEMS AND METHODS - A staged peristaltic pump system and related methods are disclosed. The system may be configured such that the working fluid pressure differential across any individual stage of the system is smaller than the pressure across the entire system. In some embodiments certain components of each stage may be sealed from fluid communication with an external environment, though working fluid may be configured to cross the boundary of the seal. In some embodiments, stages may be pressurized with respect to an external environment. | 2015-04-16 |
20150104331 | CANNULA APPARATUS AND VENTRICULAR ASSIST SYSTEMS USING THE CANNULA APPARATUS - Cannula apparatus, ventricular assist systems including the cannula apparatus, and methods of priming and placing the cannula apparatus and ventricular assist systems are described herein. | 2015-04-16 |
20150104332 | ADAPTIVE HYDRAULIC PRESSURE GENERATOR - An adaptive hydraulic pressure generator is provided for systems in which the mechanical force producing energy varies significantly, especially for wave energy systems. The pressure generator includes at least two fluid chambers with a piston surface/displacement surface arranged to reciprocate with the fluid chamber, whereby the piston surface/displacement surface acts on the fluid in the chamber by means of the said mutual reciprocating movement. The pressure generator is equipped with a control system which is arranged to connect the chambers to each other and/or to different pressure ducts in such a way that the effective area of the piston/displacement surfaces changes in accordance with the changes in the driving force exerted on the piston/displacement surfaces and/or the body forming the fluid chamber in such a way that the pressure produced by the pressure generator in the fluid supplied to the application exceeds the threshold pressure. | 2015-04-16 |
20150104333 | BUBBLE PUMP RESISTANT TO ATTACK BY MOLTEN ALUMINUM - A bubble pump is provided. The bubble pump has an interior formed from a material that is resistant to attack by molten aluminum. The interior surface may be formed from a ceramic. The ceramic may be selected from the following: alumina, magnesia, silicate, silicon carbide, or graphite, and the mixtures thereof. The ceramic may be a carbon-free, 85% Al | 2015-04-16 |
20150104334 | VARIABLE DISPLACEMENT SWASH PLATE COMPRESSOR - A variable displacement swash plate compressor includes a control pressure chamber and a displacement control valve that controls the pressure of the control pressure chamber. The displacement control valve includes an electromagnetic solenoid, a driving force transmission member, a valve body, and a pressure sensing mechanism. An accommodation chamber accommodates the pressure sensing. A valve chamber accommodates the valve body having a valve opening degree determined by an urging force applied to the valve body through the driving force transmission member and by an urging force applied to the valve body by the expansion and contraction of the pressure sensing mechanism. The valve body and the pressure sensing mechanism form a valve unit. When the electromagnetic solenoid is deactivated, the pressure of the accommodation chamber acts on a back surface of the pressure sensing mechanism so that a force in the open direction is applied to the valve unit. | 2015-04-16 |
20150104335 | INTERNAL-DRIVEN COMPRESSOR HAVING A POWERED COMPRESSOR ROTOR - The internal-driven compressor having a powered compressor rotor. The internal-driven compressor includes a compressor housing including a suction port and a discharge port, an internal driver including a rotor and a stator, the rotor and the stator located within the compressor housing, the stator located radially inward of the rotor, and a powered compressor rotor including an annular body extending about a center axis, wherein the rotor is fixed to the powered compressor rotor and configured to rotate the powered compressor rotor about the center axis in response to a force imparted by the stator. | 2015-04-16 |
20150104336 | Scalable Pumping Mechanism Utilizing Anti-Synchronized Poly-Diaphragm Stack - A diaphragm pump including at least three body plates and at least two diaphragm assemblies positioned between the at least three body plates. A series of drive fluid passages communicate with a drive side of the two diaphragm assemblies and a series of pumped fluid passages communicate with a pump side of the two diaphragm assemblies. There is an inlet check valve communicating with the series of pumped fluid passages and an outlet check valve communicating with the series of pumped fluid passages. At least one of the body plates is a doubled faced plate having either drive fluid passages on both faces or pumped fluid passages on both faces. | 2015-04-16 |
20150104337 | MULTI-STAGE HIGH PRESSURE FLANGED PUMP ASSEMBLY - A pump assembly for use within a high pressure pumping system includes housing, a head and a base. The housing contains at least one centrifugal pump stage. The head and base are attached to the housing with corresponding internal threaded connections. The head and base are further retained to the housing with corresponding external flanged connections. The external flanged connections provide redundant connections that reduce the risk of separation between the housing and the head and base. | 2015-04-16 |
20150104338 | Electromagnetic Pump - The invention relates to an electromagnetic pump comprising precisely one coil, wherein the one coil has a longitudinal axis, a ferromagnetic first core section at least partially arranged in the one coil, a ferromagnetic second core section at least partially arranged in the one coil, and a ferromagnetic armature, wherein a primary air gap is arranged between the armature and the first core section, wherein a radial secondary air gap is arranged between an insertion section of the armature and a receiving section of the second core section facing the longitudinal axis, wherein the ferromagnetic armature has a truncated cone-shaped contour narrowing in the stroke direction in a front section facing the first core section, wherein a magnetic force between the armature and the first core section is greater in a closing process of the first air gap; than a magnetic force between the armature and the second core section. | 2015-04-16 |
20150104339 | FLUID PUMP - A fluid pump includes a hollow housing, an electric motor having an armature with a commutator, a pump section rotationally coupled to the electric motor for receiving fuel at a relatively low pressure through a fuel inlet and pressurizing the fuel to a relatively high pressure, a motor brush is in electrical contact with the commutator and including a shunt wire extending therefrom, and an end cap that closes one end of the housing and defines a high pressure chamber with the housing. The end cap includes a hollow brush tower extending therefrom and defining a brush holder slidably receiving the motor brush therein such that the brush holder defines in part the high pressure chamber. The end cap also includes an aperture with the shunt wire extending therethrough such that the shunt wire is sealed with the aperture to prevent the fuel from passing therethrough. | 2015-04-16 |
20150104340 | Draft Inducer for Low Power Multistage Furnaces Utilizing an Electronically Commutated Motor System and an Associated Method of Use - A furnace assembly comprising a non-condensing furnace with a draft inducer. The draft inducer includes a permanent magnet electrically commutated motor and a draft inducer blower fan. The motor includes a stator, a rotor, a motor cooling fan, and a controller. The rotor being rotatable relative to the stator, the fan being operatively coupled to the rotor such that rotation of the rotor causes rotation of the fan, the controller being configured to selectively operate the motor in first and second different torque ranges of the rotor, with the first and second torque range operating within a fixed percentage and within a fixed percentage of each other. The controller being configured such during normal operation, the motor is not operable at any torques between the first torque range and the second torque range except during transitionary periods. | 2015-04-16 |
20150104341 | BYPASS VALVE, IN PARTICULAR COMPRESSOR BYPASS VALVE - A bypass valve ( | 2015-04-16 |
20150104342 | SCROLL-TYPE COMPRESSOR - The orbiting base plate | 2015-04-16 |
20150104343 | BALANCE SHAFT MODULE HAVING VARIABLE DISPLACEMENT OIL PUMP - A balance shaft module having a variable capacity hydraulic pump may include a first balance shaft that receives torque from an engine and a first unbalance mass is formed, a second balance shaft that receives torque from the first balance shaft through a connection gear, and a hydraulic pump that suctions and discharges oil by the rotation of the second balance shaft and varies its capacity depending on oil pressure discharged. | 2015-04-16 |
20150104344 | Methods and Systems for Coherent Imaging and Feedback Control for Modification of Materials - Methods and systems are provided for using optical interferometry in the context of material modification processes such as surgical laser or welding applications. An imaging optical source that produces imaging light. A feedback controller controls at least one processing parameter of the material modification process based on an interferometry output generated using the imaging light. A method of processing interferograms is provided based on homodyne filtering. A method of generating a record of a material modification process using an interferometry output is provided. | 2015-04-16 |
20150104345 | METHOD OF MANUFACTURING AN ORTHODONTIC BRACKET HAVING A LASER SHAPED GREEN BODY - A green metal body includes metal particles and a binder in the shape of an orthodontic bracket and/or base plate. The green metal body is fabricated by being laser-cut with a laser to shape the green metal body into the shape of an orthodontic bracket and/or to carve recesses and/or undercuts into the bonding surface of the bracket. The green metal body is sintered to shrink its volume into a denser and less porous sintered metal body configured to be an orthodontic bracket. The resultant sintered orthodontic bracket includes recesses and/or undercuts in the bonding surface to provide a mechanical aspect when bonded to a tooth. | 2015-04-16 |
20150104346 | LASER SINTERING POWDER, METHOD FOR PRODUCING STRUCTURE, APPARATUS FOR PRODUCING STRUCTURE - A laser sintering powder to be sintered by irradiation with a laser light is provided. The sintering powder includes a plurality of metal particles and a binder which binds the metal particles to one another. The binder is sublimated by the irradiation with the laser light. The average particle diameter of the metal particles is 5 μm or more and 10 μm or less, and the average particle diameter of the laser sintering powder is 30 μm or more and 50 μm or less. Further, after a powder layer is formed using the laser sintering powder, this powder layer may be compressed in the thickness direction before or after irradiation with the laser light. | 2015-04-16 |
20150104347 | Low Shrinkage Corrosion-Resistant Brass Alloy - A low shrinkage corrosion-resistant brass alloy contains 58 to 64 wt % of copper; 0.1 to 0.3 wt % of tin; less than 0.25 wt % of lead; 0.01 to 0.15 wt % of phosphorus; and more than 97.5 wt % of copper and zinc; zinc and unavoidable impurities; and more than 98 wt % of copper and zinc. It is to be noted that at least two of nickel, niobium, zirconium and aluminum is in an amount ranging from 0.01 to 0.4 wt %. | 2015-04-16 |
20150104348 | Pet Deodorizing Composition - A deodorizing composition that entraps and neutralizes malodors and is intended to be used on a pet. The deodorizing composition contains cyclodextrin, an aqueous carrier, a water soluble silicone, and a buffer system comprising citric acid. The composition has a pH from about 5 to about 8.5 and the composition is non-irritating and non-toxic to pets. | 2015-04-16 |
20150104349 | N-Alkyl-N'-Poly(Oxyalkyl)Hexahydropyrimidine-Quaternary Ammonium Salts And The Use Thereof As Corrosion Inhibitors - This invention relates to N-alkyl-N′-poly(oxyalkyl)hexapyrimidine-quaternary ammonium salts of the formulae (Ia)-(Ic) and mixtures thereof | 2015-04-16 |
20150104350 | APPARATUS FOR SEPARATING CUVETTES - An apparatus, system for analyzing, and process for separating cuvettes supplied in bulk form are presented. The apparatus comprises a reservoir with an inlet for supplying cuvettes in bulk form to a reservoir space, a separator with an outlet for outputting separated cuvettes from a separator space communicating with the reservoir space, a reservoir spiral contained in the reservoir space to transport cuvettes to the separator space by rotating the reservoir spiral, and a separator spiral contained in the separator space to transport cuvettes to the outlet by rotating the separator spiral. Adjacent turns of the separator spiral have an inter-distance dimensioned such that a cuvette can be held in a holding position in which projections projecting outwards from a body for receiving liquid rest on adjacent turns, with the body dipping into a spiral groove between the adjacent turns. | 2015-04-16 |
20150104351 | AUTOMATIC ANALYZER - A high-throughput automatic analyzer integrates a biochemical analysis section and a blood coagulation analysis section. The analyzer is capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk; a first reagent dispensing mechanism that dispenses a reagent to reaction cells on the reaction disk; a photometer that irradiates a reaction solution in the reaction cell with light; a reaction cell cleaning mechanism; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to detect transmitted or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel. | 2015-04-16 |
20150104352 | USE OF DISULFIDE BONDS TO FORM A REVERSIBLE AND REUSABLE COATING FOR NANOFLUIDIC DEVICES - A reusable coating for a nanopore structure is disclosed herein. A nanopore structure includes a substrate comprising a nanochannel and a monolayer of a chemical compound disposed onto at least a portion of a surface of the nanochannel. The chemical compound forms a reversible bond with at least one analyte binding compound introduced into the nanochannel. Methods for making and using the reusable coating are also disclosed. | 2015-04-16 |
20150104353 | DIRECTED SURFACE FUNCTIONALIZATION ON SELECTED SURFACE AREAS OF TOPOGRAPHICAL FEATURES WITH NANOMETER RESOLUTION - A method for making a single molecule receptor in a nanopore structure includes depositing a material by a physical vapor deposition (PVD) technique onto a selected interior surface of a nanochannel and functionalizing a surface of the material with a chemical compound having at least two functional groups. The material forms a patch having a diameter of about 3 to about 10,000 nanometers (nm). Also disclosed are embodiments of a nanopore structure including a single molecule receptor. | 2015-04-16 |
20150104354 | NANOFLUIDIC SENSOR COMPRISING SPATIALLY SEPARATED FUNCTIONAL SENSING COMPONENTS - A method for making multiple single molecule receptors in a nanopore structure includes depositing a first material and a second material by a physical vapor deposition (PVD) technique onto different selected interior surfaces of a nanochannel and functionalizing a surface of the first material, the second material, or both the first and second materials with a chemical compound having at least two functional groups. The first and second materials can be the same or different and form patches having diameters of about 1 to about 100 nanometers (nm). Also disclosed are embodiments of a nanopore structure including multiple single molecule receptors. | 2015-04-16 |
20150104355 | CHEMICAL OXYGEN GENERATOR WITH COMPACT IGNITION SYSTEM FOR POSSIBLE USE IN AN AIRCRAFT - A compact ignition system for chemical oxygen generators for possible use in an aircraft. The chemical oxygen generator is configured such that a majority of the ignition system can be accommodated within an interior of the generator body. In some embodiments, the ignition system is positioned within a recess of an upper surface of the core of the generator. Housing a majority of the ignition system within the generator allows the overall oxygen-generating capacity of the generator to be increased without requiring a corresponding increase in the overall length of the generator. | 2015-04-16 |
20150104356 | System and Process For Removal Of Organic Carboxylates From Mono Ethylene Glycol (MEG) Water Streams By Acidification and Vaporization Under Vacuum - A system and method for removing organic carboxylates from a mono ethylene glycol (“MEG”) stream includes a reaction vessel; means for cooling and diluting the MEG stream being routed to the reaction vessel; means for acidifying the cooled and diluted MEG stream during its residence time within the reaction vessel; and means for removing an acetic-rich overhead stream from the reaction vessel. The acidification of the cooled and diluted MEG stream occurs under a vacuum. The reaction vessel may be located downstream of a calcium removal vessel and receive a filtered bottom stream from that vessel, or it may be a single reaction vessel that cycles between a calcium removal mode and an acetate removal mode, with the pressure of the single vessel being greater during the calcium removal mode than during the acetate removal mode. | 2015-04-16 |
20150104357 | Porous Silica Aerogel Composite Membrane And Method For Making The Same And Carbon Dioxide Sorption Device - The present invention provides a porous silica aerogel composite membrane and method for making the same and a carbon dioxide sorption device. The porous silicon oxide aerogel composite membrane includes a porous aluminum oxide membrane having a plurality of macro pores with an average diameter larger than 50 nm and a porous silica aerogel membrane formed on at least one side of the porous aluminum oxide membrane and the macro pores of surface layers of the porous aluminum oxide membrane where the porous silica aerogel membrane has a plurality of meso pores with an average diameter of 2˜50 nm and is derived from methyltrimethoxysilane precursor by a sol-gel synthetic method. | 2015-04-16 |
20150104358 | NUCLEIC ACID EXTRACTION DEVICE, NUCLEIC ACID EXTRACTION KIT, AND NUCLEIC ACID EXTRACTION APPARATUS - A nucleic acid extraction device has a tube in which a first plug formed of an oil, a second plug formed of a washing liquid which does not mix with an oil, a third plug formed of an oil, a fourth plug formed of an eluate which does not mix with an oil, and a fifth plug formed of an oil are arranged in this order, and the tube is subjected to an antistatic treatment. | 2015-04-16 |
20150104359 | Density Phase Separation Device - A mechanical separator for separating a fluid sample into first and second phases within a collection container is disclosed. The mechanical separator may have a separator body having a through-hole defined therein, with the through-hole adapted for allowing fluid to pass therethrough. The separator body includes a float, having a first density, and a ballast, having a second density greater than the first density. A portion of the float is connected to a portion of the ballast. Optionally, the float may include a first extended tab adjacent a first opening of the through-hole and a second extended tab adjacent the second opening of the through-hole. In certain configurations, the separator body also includes an extended tab band disposed about an outer surface of the float. The separator body may also include an engagement band circumferentially disposed about at least a portion of the separator body. | 2015-04-16 |
20150104360 | Combinatorial Flow System and Method - A reactor assembly having a plurality of reaction chambers defined therein is provided. The reactor assembly includes a fluid flow module that provides a pressurized control flow of fluid from an open container. In another embodiment, the reactor block includes a plurality of passageways defined over a surface of a substrate to accommodate the combinatorial processing in order to obtain multiple data points from a single substrate. | 2015-04-16 |
20150104361 | PROCESSES FOR RECOVERING RARE EARTH ELEMENTS AND RARE METALS - There are provided processes for recovering at least one rare earth element. Such processes comprise obtaining an acidic composition comprising (i) at least one rare earth element and optionally at least one rare metal; and reacting the composition with a precipitating agent so as to substantially selectively precipitate a first rare earth element and optionally a first rare metal. For example, various rare earth elements (such as scandium, yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, etc) and various rare metals (such as indium, zirconium, lithium, gallium, etc.) can be extracted by using such processes. | 2015-04-16 |
20150104362 | METHODS AND APPARATUS FOR RECOVERING MOLYBDENUM IN URANIUM IN-SITU RECOVERY PROCESS - A method of recovering molybdenum includes introducing resin comprising molybdenum anions into an elution vessel and eluting (separating) the molybdenum anions from the resin to form a molybdenum rich eluent. Small amounts of uranium within the eluent is precipitated into sodium diuranate and removed. A further precipitation process is performed to form ferrimolybdate from the molybdenum rich eluent, thus recovering molybdenum. The resin comprising the molybdenum anions may be generated by (1) moving a pregnant lixiviant (containing uranium and molybdenum) through a first extraction apparatus to capture uranium anions in resin and producing a barren lixiviant (containing mostly molybdenum, with small amount of uranium), and (2) moving the barren lixiviant through a second extraction apparatus to capture mostly molybdenum anions in resin. | 2015-04-16 |
20150104363 | REAGENT DOSER DIAGNOSTIC SYSTEM AND METHOD - Systems and methods are disclosed for determining or diagnosing a reagent dosing system failure to provide sufficient reagent to an exhaust aftertreatment system that includes an SCR catalyst to satisfy a reagent dosing command. | 2015-04-16 |
20150104364 | PROCESSES USING MOLECULAR SIEVE SSZ-96 - The present disclosure is directed to processes using a new crystalline molecular sieve designated SSZ-96, which is synthesized using a 1-butyl-1-methyl-octahydroindolium cation as a structure directing agent. | 2015-04-16 |
20150104365 | Flue-Gas Purification and Reclamation System and Method Thereof - A flue-gas purification system includes a flue-gas cycling system, a reacting means, and an absorbent adding system having at least a catalytic absorbent, wherein the catalytic absorbent is being gasified for reacting with the flue-gas in the reacting means in a homogenous gas-gas phase reacting manner. Therefore, the purification system has fast reaction rate between the pollutants of the flue-gas and the catalytic absorbent, which is preferably ammonia, to efficiently remove pollutants, so as to effectively purify the flue-gas. | 2015-04-16 |
20150104366 | AMINO-SILOXANE COMPOSITION AND METHODS OF USING THE SAME - An amino-siloxane composition is presented. The amino-siloxane composition includes structure (I): | 2015-04-16 |
20150104367 | ACYCLIC AZA-CONTAINING LIGANDS FOR USE AS CATALYTIC CARBON CAPTURE SYSTEMS - According to one embodiment, a catalyst includes a metal ion, and an acyclic ligand having at least one aza-containing moiety, where the ligand is complexed to the metal ion. | 2015-04-16 |
20150104368 | INORGANIC PHOSPHATE COMPOSITIONS AND METHODS - Disclosed and described are multi-component inorganic phosphate formulations of acidic phosphate components and basic oxide/hydroxide components. Also disclosed are high solids, atomizable compositions of same, suitable for spray coating. | 2015-04-16 |
20150104369 | POLYSILICON TRANSPORTATION DEVICE AND A REACTOR SYSTEM AND METHOD OF POLYCRYSTALLINE SILICON PRODUCTION THEREWITH - A method and system for reduction or mitigation of metal contamination of polycrystalline silicon are disclosed. A conveyance device comprising a flexible synthetic resin tube having an inner surface at least partially coated with an inner layer comprising elastomeric microcellular polyurethane is disclosed for use in fluidized bed reactor operations associated with manufacture and product handling procedures for ultra pure granular polysilicon. Use of the conduit to effect passage of the polysilicon mitigates foreign metal contact contamination from sources otherwise typically present in such manufacturing units. | 2015-04-16 |
20150104370 | METHOD FOR PRODUCING SILICON METAL AND POROUS CARBON - The method for producing silicon metal and porous carbon from rice hulls is provided. The method comprises a first step S | 2015-04-16 |
20150104371 | CATALYTIC AMMONIA SYNTHESIS BY TRANSITION METAL MOLECULAR COMPLEXES - This invention relates to molecular catalysts and chemical reactions utilizing the same, and particularly to catalysts and catalytic methods for reduction of molecular nitrogen. The molecular catalytic platform provided herein is capable of the facile reduction of molecular nitrogen under useful conditions such as room temperature or less and atmospheric pressure or less. | 2015-04-16 |
20150104372 | Single-Step, Solvent-Free, Catalyst-Free Preparation of Holey Carbon Allotropes - Methods for forming holey carbon allotropes and graphene nanomeshes are provided by the various embodiments. The various embodiments may be applicable to a variety of carbon allotropes, such as graphene, graphene oxide, reduced graphene oxide, thermal exfoliated graphene, graphene nanoribbons, graphite, exfoliated graphite, expanded graphite, carbon nanotubes (e.g., single-walled carbon nanotubes, double-walled carbon nanotubes, few-walled carbon nanotubes, multi-walled carbon nanotubes, etc.), carbon nanofibers, carbon fibers, carbon black, amorphous carbon, fullerenes, etc. The methods may produce holey carbon allotropes without the use of solvents, catalysts, flammable gas, additional chemical agents, or electrolysis to produce the pores (e.g., holes, etc.) in the carbon allotropes. In an embodiment, a carbon allotrope may be heated at a working window temperature for a working period of time to create holes in the carbon allotrope. | 2015-04-16 |
20150104373 | TRIMANGANESE TETRAOXIDE AND ITS PRODUCTION PROCESS - Trimanganese tetraoxide has high reactivity with a lithium compound, is excellent in handling efficiency, and is suitable as a manganese material of a lithium manganese oxide, and its production process. Trimanganese tetraoxide particles including trimanganese tetraoxide primary particles having an average primary particle size of at most 2 μm agglomerated, the pore volume of pores being at least 0.4 mL/g. The most frequent pores are preferably pores having a diameter of at most 5 μm. The trimanganese tetraoxide particles can be obtained by producing trimanganese tetraoxide particles, which includes directly crystallizing trimanganese tetraoxide from a manganese salt aqueous solution, wherein the manganese salt aqueous solution and an alkali aqueous solution are mixed so that the oxidation-reduction potential is at least 0 mV and OH | 2015-04-16 |
20150104374 | TITANIUM OXIDE, CONDUCTIVE TITANIUM OXIDE, AND PROCESSES FOR PRODUCING THESE - Titanium dioxide and an electro-conductive titanium oxide which each includes particles having a large major-axis length in a large proportion and comprises columnar particles having a satisfactory particle size distribution. A titanium compound, an alkali metal compound, and an oxyphosphorus compound are heated/fired in the presence of titanium dioxide nucleus crystals having an aspect ratio of 2 or higher to grow the titanium dioxide nucleus crystals. Subsequently, a titanium compound, an alkali metal compound, and an oxyphosphorus compound are further added and heated/fired in the presence of the grown titanium dioxide nucleus crystals. Thus, titanium dioxide is produced which comprises columnar particles having a weight-average major-axis length of 7.0-15.0 μm and in which particles having a major-axis length of 10 μm or longer account for 15 wt. % or more of all the particles. A solution of a tin compound and a solution of compounds of antimony, phosphorus, etc. are added to a suspension obtained by suspending the titanium dioxide. The particles are sedimented. Subsequently, the product obtained is heated/fired to produce an electro-conductive titanium oxide which comprises the titanium dioxide and an electro-conductive coating formed on the surface thereof. | 2015-04-16 |
20150104375 | STARTING MATERIAL ALUMINA FOR PRODUCTION OF SAPPHIRE SINGLE CRYSTAL AND METHOD FOR PRODUCING SAPPHIRE SINGLE CRYSTAL - Disclosed is an alumina raw material for the production of a sapphire single crystal, which contains at least one element X selected from the group consisting of elements (1) to (3) shown below, wherein the concentration of the element X is 10 ppm or more and 1,000 ppm or less expressed in terms of atoms, and each concentration of silicon (Si), gallium (Ga), germanium (Ge) and tin (Sn) is 10 ppm or less expressed in terms of atoms. | 2015-04-16 |
20150104376 | METHOD OF ANNEALING SAPPHIRE - A method of annealing at least one sapphire lamina is disclosed. The method comprises at least two different heating steps and produces an annealed sapphire lamina having improved optical properties that can be used for fabricating a cover plate of an electronic device. The cover plate and electronic device comprising the annealed sapphire lamina are also disclosed. | 2015-04-16 |
20150104377 | METHOD FOR MAKING MOLECULAR SIEVE SSZ-96 - A method for making a new crystalline molecular sieve designated SSZ-96 is disclosed using a 1-butyl-1-methyl-octahydroindolium cation as a structure directing agent. | 2015-04-16 |
20150104378 | SYNTHESIS OF BOROSILICATE TON-FRAMEWORK TYPE MOLECULAR SIEVES - A method is disclosed for synthesizing borosilicate TON-framework type molecular sieves in a hydroxide media using a 1,3-dimethylimidazolium cation or a 1,4-bis(N-methylimidazolium)butane dication as a structure directing agent. | 2015-04-16 |
20150104379 | MOLECULAR SIEVE SSZ-96 - A new crystalline molecular sieve designated SSZ-96 is disclosed. SSZ-96 is synthesized using a 1-butyl-1-methyl-octahydroindolium cation as a structure directing agent. | 2015-04-16 |
20150104380 | Biodegredable Carrier For Carrying Radioisotope And Kit Containing The Same - The present invention relates to a biodegradable carrier for carrying a radioisotope, which is formed from at least one biodegradable polymer selected from the group consisting of poly(lactic-co-glycolic acid) (PLGA), poly(lactic acid) (PLA), poly(ε-caprolactone) (PCL), chitosan, poly(γ-glutamic acid) (PGA), and polyethylene glycol (PE) in which its hydroxyl group is substituted with an amino group and grafted with tetraazocyclododecanetetraacetic acid monosuccinimide ester (DOTA-NHS), in which nitrogen atoms contained in the DOTA-NHS are provided for coordinating with a radioisotope. The present invention also relates to a kit which includes a first container containing the biodegradable carrier for carrying a radioisotope according to the present invention and a second container containing a radioisotope. | 2015-04-16 |
20150104381 | Enhanced in vivo Targeting of Radiolabelled Peptides with the Means of Enzyme Inhibitors - The present invention relates to a compound that inhibits the activity of a degrading enzyme for use in combination with a therapeutic or diagnostic compound, preferably a moiety conjugated peptide, in the diagnosis and/or treatment of a disease, in particular cancer, to enhance targeting of the therapeutic or diagnostic compound to the disease site. | 2015-04-16 |
20150104382 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND TARGETING CANCER CELLS OF ALIMENTARY CANAL ORIGIN - Screening and diagnostic reagents, kits and methods for primary and or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of for treating and preventing primary and/or metastatic stomach for esophageal cancer are disclosed. | 2015-04-16 |
20150104383 | SELENOCYSTEINE MEDIATED HYBRID ANTIBODY MOLECULES - The invention provides methods and compositions employing hybrid molecules of a synthetic molecule and antibody or antibody fragment comprising a selenocysteine residue, wherein the synthetic molecule is covalently linked to the antibody or antibody fragment at the selenocysteine residue. The invention also provides a composition comprising a hybrid molecule as described above and a pharmaceutically acceptable carrier. The invention further provides for methods of making the hybrid molecules, and methods of using the hybrid molecule described above to inhibit cell surface receptor binding. | 2015-04-16 |
20150104384 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES - The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds. | 2015-04-16 |
20150104385 | RADIO-PHARMACEUTICAL COMPLEXES - A tissue-targeting complex comprising a tissue targeting moiety, an octadentate hydroxypyridinone-containing ligand comprising four HOPO moieties and the ion of an alpha-emitting thorium radionuclide, where at least one of the four HOPO moieties is substituted at the N-position with a hydroxyalkyl solubilising group and wherein the tissue targeting moiety has binding affinity for the CD22 receptor. Methods of treatment utilising such complexes and methods of formation of such complexes are provided. | 2015-04-16 |
20150104386 | ISOTOPE PREPARATION METHOD - The present invention provides a method for the generation of | 2015-04-16 |
20150104387 | PSMA-TARGETING COMPOUNDS AND USES THEREOF - Prostate-specific membrane antigen (PSMA) targeting compounds are described. Uses of the compounds for imaging, therapy, cell sorting, and tumor mapping are also described. | 2015-04-16 |
20150104388 | ANALOGS OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) AND METHODS FOR THEIR USE - This invention relates to novel analogs of pituitary adenylate cyclase-activating polypeptide (PACAP), which are agonists for the PACAP/vasoactive intestinal peptide (VIP) receptors: PAC1, VPAC1 and VPAC2 receptors. These PACAP analogs can be used as prophylactic/therapeutic agents for a wide range of medical disorders, including (but not limited to) cancer and autoimmune disease. These PACAP analogs can be coupled to suitable radionuclides and used in the localization, diagnosis and treatment of disseminated cancers and metastatic tumors, or coupled to small molecule therapeutics and used as vectors for targeted drug delivery. This invention also provides pharmaceutical compositions of one or more PACAP-like compounds of the invention either alone or in combination with one or more other prophylactic/therapeutic agents. | 2015-04-16 |
20150104389 | RADIOLABELLED GLUTAMINYL CYCLASE (QC) INHIBITORS AND USES OF SAME - Radiolabeled glutaminylcyclase (QC) inhibitors as imaging agents, in particular, but not exclusively, as medical imaging agents for the detection of neurological disorders; and pharmaceutical compositions, methods and kits for detecting neurological disorders, using the radiolabeled inhibitors. | 2015-04-16 |
20150104390 | ALL-PROTEIN IMPLANTABLE, RESORBABLE REFLECTORS - The invention provides for compositions and process for fabricating an optical reflector constructed from biocompatible and bioresorbable silk fibroin proteins. For example, the silk retroreflectors may be built based on millimeter size microprism arrays to rotate the image plane of imaged cortical layers, thus enhancing the amount of photons that are detectable in the reflected direction when inserted in a sample to be analyzed, and ultimately increasing in contrast ratio in multiphoton microscopy. Such device can be used as a label-free, biocompatible, bioresorbable, implantable device for various applications ranging from medical imaging/diagnostics, drug/therapeutic delivery, to food chain safety and environmental monitoring. | 2015-04-16 |
20150104391 | METHOD FOR PREPARING PATIENT-SPECIFIC GLIOBLASTOMA ANIMAL MODEL, AND USES THEREOF - Provided is a method for producing a glioblastoma mouse model and the mouse model produced thereby, the method including the steps of: (a) dividing a glioblastoma tissue, isolated from a patient, into 4 or more sections, and collecting one or more pieces from each of the sections; (b) dissociating a mixture of the collected pieces into glioblastoma cells as single cells; and (c) orthotopically transplanting a graft sample containing the glioblastoma cells obtained in step (b), into the brain of an immunodeficient mouse. Further provided are a method of screening a glioblastoma therapeutic agent using the mouse model and a method of providing information for selection of a patient-specific glioblastoma therapy using the mouse model. The glioblastoma mouse model shows the same genetic, morphological and pathological characteristics as those of the parental tumor, and it allows screening patient-specific glioblastoma therapeutic agent or selecting safer and more effective patient-specific glioblastoma therapy. | 2015-04-16 |
20150104392 | COMPOSITIONS, BIOMARKERS AND THEIR USE IN THE TREATMENT OF CANCER - The present invention relates to compositions, biomarkers, and their use in treatment of cancer. In some embodiments, the invention relates to the use of several biomarkers in methods for determining the responsiveness of a human subject to a specific compound, methods for monitoring the efficacy of the compound, or methods for treating a human subject. | 2015-04-16 |
20150104393 | NUTRIENT COMBINATIONS FOR AFFECTING AN AGING PROCESS - A composition comprising an effective amount of a combination of mitochondrial nutrients sufficient to affect mitochondrial function. A method of affecting an aging process in a subject comprising administering to a subject an effective amount of a combination of mitochondrial nutrients sufficient to affect an aging process. A method of identifying a combination of mitochondrial nutrients sufficient to affect an aging process in a subject, the method comprising: administering a combination of mitochondrial nutrients to a subject; and determining whether the mitochondrial nutrients affect an aging process in the subject. | 2015-04-16 |
20150104394 | CHARACTERIZATION OF BIOLOGICAL TISSUES AT A CELLULAR LEVEL USING RED AND FAR-RED FLUORESCENT DYES - A method for observing the morphology of a biological tissue is disclosed. The method involves using a fluorescent dye on the biological tissue, where the fluorescent dye is selected from patent blue V, isosulfan blue, toluidine blue, hypericin, indocyanine green, MVAC, or doxorubicin, and using a microscopic linear or non-linear imaging system to form an image of the biological tissue, where the fluorescence of the dye reveals the morphology of the tissue at cellular scale. | 2015-04-16 |