16th week of 2012 patent applcation highlights part 48 |
Patent application number | Title | Published |
20120094774 | ELASTIC JOINT BODY - The present invention relates to an elastic joint body for a shaft arrangement for the articulated connection of two shaft sections, comprising a plurality of bushes disposed in circumferential direction at predetermined angular distances in relation to a centre line of the joint body, a plurality of loop assemblies, wherein each loop assembly is looped around in each case two adjacent bushes and at least two loop assemblies are looped around each bush, a support device that is disposed for axially guiding the plurality of loop assemblies on at least one of the bushes, and a rubber-elastic sheath, into which the loop assemblies, the support device and the bushes are at least partially embedded. | 2012-04-19 |
20120094775 | UNIVERSAL JOINT MECHANISM - The various embodiments herein provide a constant speed universal mechanical joint mechanism with crossover angle up to 90 degrees and more. The universal mechanical joint comprises an input coupling, an output coupling, at least one input shaft, at least one output shaft, a plurality of guide arms, at least three connecting arms, a plurality of connecting means, a plurality of external retaining rings and a plurality of bearings. The input coupling is connected to the input shaft and the output coupling is connected to the output shaft in such a way that the plurality of retaining rings joins each of the input coupling and the output coupling with the plurality of guide arms and the plurality of connecting means. The plurality of retaining rings and the plurality of bearings are used to connect each of the plurality of guide arms to the at least three connecting arms. | 2012-04-19 |
20120094776 | APPARATUS COMPRISING A SHAFT AND A BALANCING SLEEVE - An apparatus including a shaft mounted for rotation and a balancing sleeve is provided. The balancing sleeve functions to balance the shaft during rotation and includes first and second ends. The first end is secured to the shaft so that the balancing sleeve is substantially concentric with the shaft and rotates with the shaft. The second end incorporates balancing weight to balance the shaft at lower speeds of rotation of the shaft where there is substantially no flexing of the shaft. The lengthwise stiffness of the balancing sleeve is matched to the lengthwise stiffness of the shaft to maintain balance of the shaft at higher speeds of rotation of the shaft where there is flexing of the shaft. | 2012-04-19 |
20120094777 | DRIVE SHAFT, IN PARTICULAR RADIAL SHAFT FOR A GAS-TURBINE ENGINE - A drive shaft, in particular a radial shaft for a gas-turbine engine, includes a metallic and hollow shaft shank | 2012-04-19 |
20120094778 | CUSHION BUMPER FOR COUPLING A BUTT EXTENSION WITH A POOL CUE AND A POOL CUE WITH THE CUSHION BUMPER - A replaceable cushion bumper for coupling a butt extension with a butt end of a pool cue is disclosed. The cushion bumper includes a male stub to be screwed into the butt end and a cushion overwrapping the male stub. The male stub includes a female thread extending through the center so as to receive a male thread of the butt extension. The cushion also includes a bumper bore extending to the female thread of the male stub so as to receive the male thread of the butt extension. A pool cue with the cushion bumper is also disclosed. | 2012-04-19 |
20120094779 | GOLF CLUB HEAD WITH UNDERCUT - A golf club head having a translucent insert disclosed. The club head includes a body defining a striking face, a top line, a sole, a back, a heel, and a toe. The back contains a cavity that extends in a direction substantially perpendicular to the face. A recess is provided within the cavity, with the recess extending away from the cavity and toward the sole. A translucent insert, such as a vibration dampening member, may be provided within the recess. The insert may contain secondary inserts, such as weight members, therein in strategic locations. The insert may completely fill the recess, or may fill only a portion thereof. | 2012-04-19 |
20120094780 | Device for Changing Mass Characteristics of a Golf Club - A device for changing the mass characteristics of a golf club may include a first movable mass. The device may also include a first movable mass guide configured to accommodate longitudinal travel of the first movable mass along the golf club shaft. The first movable mass guide may not extend beyond the distal end of the golf club shaft. The golf club head may include a second movable mass and a second movable mass guide that accommodates travel of the second movable mass. | 2012-04-19 |
20120094781 | GOLF CLUB HAVING REMOVABLE SOLE WEIGHT USING CUSTOM AND INTERCHANGEABLE PANELS - A golf club head is presented comprising a sole including a removable panel secured to the sole via a non-threaded attachment assembly. Further, the removable panel may have a large surface area relative to its thickness, resulting in a chip-like or wafer-like weight member. This design allows the mass of the removable panel to be spread substantially along the surface of the sole as opposed to in the interior of the club head. The golf club head may comprise more than one removable panel. A removable panel of the present invention may generally comprise one or more discrete areas of higher basis weight or higher density. Even further, the removable panel may generally be releasably attached via a quick disconnect mechanism that allows easy interchangeability. | 2012-04-19 |
20120094782 | CONTRAST-ENHANCED GOLF CLUB HEADS - Golf club heads include white diffusing top surfaces to aid in club head alignment. Wood type club heads also include a dark diffusing club face so that a crown/face border is emphasized. Scorelines in wood type clubs can be provided with an intermediate contrast surface, and can be displaced from club face center to accommodate player perception when confronted with a white diffusing crown. Putter heads can include dark diffusing alignment lines, and iron-type club heads can include white diffusing surfaces at a sole portion of a club face, at a top line, or a top portion of a club face. | 2012-04-19 |
20120094783 | GOLF BALL - The present invention provides a golf ball having a center and at least one intermediate layer covering the center and a cover, wherein at least one of the intermediate layer is formed from a composition comprising, as a resin component, (A) a polyamide copolymer containing (a-1) a polymerized fatty acid, (a-2) sebacic acid and/or azelaic acid, (a-3) a polyamine component as an essential component, and (B) at least one member selected from (b-1) a binary copolymer composed of an olefin and an α,β-unsaturated carboxylic acid, (b-2) a metal ion-neutralized product of a binary copolymer composed of an olefin and an α,β-unsaturated carboxylic acid, (b-3) a ternary copolymer composed of an olefin, an α,β-unsaturated carboxylic acid and an α,β-unsaturated carboxylic acid ester, and (b-4) a metal ion-neutralized product of a ternary copolymer composed of an olefin, an α,β-unsaturated carboxylic acid and an α,β-unsaturated carboxylic acid ester. | 2012-04-19 |
20120094784 | GOLF BALL WITH SINGLE THERMOPLASTIC COVER LAYER OF HETEROGENEOUS COMPOSITION - The invention relates generally to golf balls, and more specifically, to a golf ball having a single cover layer that is comprised of a blend of two or more distinct resinous materials. | 2012-04-19 |
20120094785 | Methods For Encouraging Use Of Greenhouse Gas Reducing Golf Balls - This disclosure provides methods for encouraging golfers and other users to use greenhouse gas reducing golf balls. Greenhouse gas reducing golf balls may include carbon dioxide absorbents, in order that the golf ball may reduce atmospheric carbon dioxide levels to aid in alleviating global warming. The methods may include determining a degree of usage of a used greenhouse gas reducing golf ball, and awarding a reward to a user based on the degree of usage. The methods thereby promote the use of certain greenhouse gas reducing golf balls instead of conventional golf balls, and encourages the reuse of those greenhouse gas reducing golf balls. | 2012-04-19 |
20120094786 | BASEBALL TRAINING DEVICE AND METHOD - A baseball training system to teach proper swing technique comprising a first tee adapted to support a baseball and a second tee adapted to support a baseball, a tee support configured to hold the first tee and a second tee vertically and separated from each other by a horizontal distance, d, a rod, and a belt configured to be worn around a user's stomach and to hold the rod in an approximate horizontal position across the front of the user's stomach. | 2012-04-19 |
20120094787 | FOOTBALL TRAINING APPARATUS AND METHOD - A football training apparatus, system and method utilizes a microcontroller-LED display, located on a football-type projectile, wherein a visual display is displayed by a display element during spiral motion of the projectile. The visual display may be, for example, a word, symbol or color. To train a receiving player's ball-watching skills, the player is instructed to call out the visual display while the ball is spiraling and in flight in his direction. | 2012-04-19 |
20120094788 | TACKLE PRACTICE APPARATUS AND A METHOD FOR PRACTISING TACKLING IN A CONTACT SPORT - Tackle practice apparatus ( | 2012-04-19 |
20120094789 | SYSTEM AND METHOD OF USING SHEAR THICKENING MATERIALS IN SPORTS PRODUCTS - A sports product may include a support member and an impact region configured to impact an object. The impact region may be coupled to the support member. The sports product may also include a shear thickening material in at least one of the support member or the impact region. The shear thickening material may be configured to exhibit shear thickening behavior when an impact occurs between the impact region and the object. | 2012-04-19 |
20120094790 | Teardrop Ring Tossing Game - The present invention is a ring for a game of skill, generally comprising a single strip having first and second ends, wherein said first and second ends are attached to one another to form a single endless ring having a corner on one side of said ring and a teardrop-shaped opposing side opposite said corner. In some embodiments the ring is a single continuous piece. Alternative embodiments of the present invention call for the game piece to be flexible, and for utilizing attachment mechanisms and curvature retention mechanisms to further adjust and retain the curvature of the ring, all for the purpose of affecting the trajectory of the ring when thrown. | 2012-04-19 |
20120094791 | ISOLATION DAMPER PULLEY FOR VEHICLE - A damper pulley for a vehicle may include a damper portion connected to a crankshaft, a pulley portion connected to the damper portion, and a bearing portion disposed between the damper portion and the pulley portion, wherein the bearing portion includes a first bearing supporting a load applied in an axial direction and a second bearing supporting a load applied in a direction perpendicular to the axial direction, and the first and second bearings are engaged through protrusions and depressions. | 2012-04-19 |
20120094792 | TORQUE BIASED FRICTION HINGE FOR A TENSIONER - A pivot joint for a single blade spring tensioner or double blade spring tensioner generates a biased friction loss at a pivot joint. The friction torque generated in one direction of joint rotation is greater than the friction torque generated in the opposite direction of rotation. In one embodiment, the direction of torque bias at the joints is used to make the damping of the blade spring greater in compression than in extension. High damping in compression and low damping in extension is a desirable characteristic for a tensioner in most applications. The device may be designed to act as a one-way clutch or as a two-way clutch. The device may also be designed to apply large friction torques only when the joint undergoes large amplitude motions (loss of control). | 2012-04-19 |
20120094793 | BELT TENSIONING UNIT - A belt tensioning unit ( | 2012-04-19 |
20120094794 | Universal Child Safety Tensioner for Roller Blind - The present invention is a tensioner for securing a loop of roller blind chain to a window frame and to a wall adjacent the window frame. The tensioner includes a member having a top portion with a peripheral edge, a bottom portion, opposite end portions, opposite side portions, and a central aperture passing through the opposite side portions and positioned between the opposite end portions and between the top and bottom portions. The central aperture is dimensioned to permit the roller blind chain to pass there through. The member has a first thickness separating the opposite first and second sides of the member and a second thickness between the central aperture and the peripheral edge, the first thickness and the second thickness each being greater than the distance separating the beads of the chain. The member is configured such that the member is mountable in both a vertical orientation on the window frame wherein the opposite side portions are oriented in horizontal alignment and the end portions are oriented in vertical alignment and a horizontal orientation wherein the opposite side portions are oriented in vertical alignment and the end portions are oriented in horizontal alignment. Finally, the top portion of the member is curved such that the loop of roller chain is positioned perpendicular to the wall when the member is mounted in its horizontal orientation. | 2012-04-19 |
20120094795 | V-SHAPED TRANSMISSION BELT AND BELT WHEEL AND METHOD OF USE - The V-shaped transmission belt has concave and convex teeth on the inner diameter surface which are designed according to the engaging transmission principle. For the belt wheel with a V-shaped groove, the concave tooth on the bottom of the V-shaped groove comprises an engaging transmission section designed according to the engaging transmission principle, and a rolling friction transmission section disposed symmetrically on two sides of the engaging transmission section. | 2012-04-19 |
20120094796 | RESIN PULLEY - A resin pulley includes an outer cylindrical portion including an outer circumferential surface on which a belt is to be wound, an inner cylindrical portion, and a plurality of ribs connecting an inner circumferential surface of the outer cylindrical portion and an outer circumferential surface of the inner cylindrical portion, which are formed of a resin material. The ribs are provided so as to be inclined towards a circumferential direction relative to a radial imaginary line as viewed in an axial direction. Radially outer end portions of the ribs are formed such that inclination angles of the respective radially outer end portions relative to the radial imaginary line increase as the ribs extend radially outward, and radially inner end portions of the ribs are formed such that inclination angles of the respective radially inner end portions relative to the radial imaginary line increase as the ribs extend radially inward. | 2012-04-19 |
20120094797 | HYDRAULIC CONTROL SYSTEM OF CONTINUOUSLY VARIABLE TRANSMISSION FOR VEHICLE - A hydraulic control system of a continuously variable transmission for a vehicle reduces cost and improves quality reliability by adding switch valve function to a manual valve. The hydraulic control system may control a first brake operated at a first forward speed, a first clutch operated at a second forward speed, and a second brake operated at a reverse speed. The first clutch and the second brake may be operated by operation pressure controlled by a first proportional control solenoid valve and supplied through a manual valve, and the first brake may be operated by operation pressure controlled by a second proportional control solenoid valve, wherein the second proportional control solenoid valve controls hydraulic pressure received from the manual valve to be supplied to the first brake as the operation pressure. | 2012-04-19 |
20120094798 | WELDED STRUCTURE AND WELDING METHOD - Disclosed are a welded structure and a welding method which make it possible to improve welding strength and welding quality. A welded structure in which a first member and a second member are joined by means of welding, wherein the first member comprises a second-member joining part which is joined to the second member, and the second member comprises a first-member joining part which is joined to the first member. If the direction in which the first member and the second member are arranged is the first direction, and the direction intersecting the first direction is the second direction, the welded structure comprises a cavity part which is provided between the first-member joining part and the second-member joining part, and a welded part which is provided between the cavity part and both end parts in the second direction of the joining surface where the first-member joining part and the second-member joining part are joined. | 2012-04-19 |
20120094799 | MULTI-SPEED TRANSMISSION WITH EXTERNAL DRIVE GEARSETS - A transmission is provided having an input member, an output member, three planetary gear sets, two external gear sets or sprocket sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. Each of the external gear sets includes first and second members. The torque transmitting devices include clutches and brakes. | 2012-04-19 |
20120094800 | VEHICULAR SHIFT CONTROL DEVICE - A vehicular shift control device is provided that controls the input rotational speed of a geared transmission by adjusting the rotational speed of a drive source at downshift of the geared transmission. The greater the deceleration of the vehicle, the smaller is set the change gradient of the input rotational speed of the geared transmission. Therefore, even if the decrease rate of the post-shifting synchronization rotational speed is great, the incident angle γ of the input rotational speed of the geared transmission relative to the post-shifting synchronization rotational speed is maintained as a large angle. Even when the deceleration of the vehicle during downshift is great, the downshift is smoothly executed without producing an excessive synchronization shock. | 2012-04-19 |
20120094801 | Motor Control Device for Working Vehicle - A motor control device for a working vehicle includes: a travel drive device that transmits rotation of a motor to wheels through a torque converter; a first selection device to be operated so as to select one of a power mode and an economy mode; a second selection device that is different from the first selection device; a mode switching device that switches from the economy mode to the power mode if the second selection device is operated in a state where the economy mode has been selected by the first selection device; and a speed restriction device that, when the economy mode is set, restricts a maximum rotational speed of the motor to a lower speed side than that when the power mode is set. | 2012-04-19 |
20120094802 | VEHICLE CONTROLLER - A vehicle controller includes an F/C control section, a battery voltage detection section, an AT control section, an alternator, and an ECU. The ECU determines the difference between a target deceleration for varying deceleration smoothly and a deceleration attained at each gear stage as a target deceleration which is generated by the alternator. The ECU compensates for the difference between target deceleration and the deceleration by the target deceleration to smooth variations in the deceleration of the whole vehicle, thereby improving drivability. | 2012-04-19 |
20120094803 | Engine Speed Control Device For Industrial Vehicle - An engine speed control device for an industrial vehicle includes an approach detector that detects an approach of the industrial vehicle to an object to be approached; and an engine speed controller that restricts an upper limit of a rotation speed of an engine when the approach detector detects an approach of the industrial vehicle to an object to be approached. | 2012-04-19 |
20120094804 | WEIGHT-LIFTING EXERCISE MACHINE - A weight-lifting exercise machine enables an athlete to lift a mass from an initial resting position. After the athlete releases the mass, the machine cushions the fall of the mass, such that the mass returns to its resting position without assistance from the athlete. The movements of the athlete and the mass can be tracked, preferably by wireless accelerometers attached respectively to the athlete and the mass, and data on such movements can be stored and analyzed. The machine provides a monitor to enable the athlete to track the progress of the exercise, and to determine whether the exercise is being performed correctly. | 2012-04-19 |
20120094805 | MONITORING APPARATUS FOR A GYMNASTIC MACHINE - Apparatus and method for monitoring a body portion of a user during the use of a gymnastic machine provided with a video monitoring apparatus; this method comprising a phase of defining the body portion to be monitored, followed by a phase of visually and continuously monitoring this body portion through the video monitoring apparatus; this last phase comprising a sub-phase of synchronizing the trend over time of the value of at least one operating parameter of the video monitoring apparatus with a motion of the body portion described on the basis of given kinematic information acquired by a control unit of the gymnastic machine. | 2012-04-19 |
20120094806 | Adjustable Inhalation Resistence Exercise Device - A respiratory inhalation resistence exercise device with a separate air inlet and air outlet. A mask, which provides a substantially airtight perimeter seal during inhaling and lung expansion, is provided which covers at least the user's nose and mouth. Multiple air inlet inserts are provided for interchangeable use in the air inlet, allowing different rates and resistence to airflow, as provided. The device is held in place, hands free, by straps around the user's head. The device may also cover the entire face of a user, with lenses in eye openings for sight. The device may be utilized continually in vigorous exercise, without use of a mouthpiece, without significant protruding parts, without movable valves or parts, and held in place without limitation on the user's activity. | 2012-04-19 |
20120094807 | Trampoline with Dual Spring Elements - A trampoline provides higher performance and greater shock absorption capability by utilizing pairs of springs to connect the rebounding mat to the supporting frame. The springs in each pair are coupled to a common junction on the periphery of the rebounding mat, being disposed vertically with respect to each other. The upper spring in each pair is directly connected to the rebounding mat and the trampoline frame to initially to tension the mat in the equilibrium position. The lower spring in each pair is coupled to the frame and then to rebounding mat via a linkage arm such that it comes substantially under tension only as the corresponding upper spring is stretched. Depending on the level of impact force on the trampoline mat both springs extend, such that their combined stored energy propels the user upward on the return bounce. However, as each spring pair engages in stages the shock of the users initially landing is gradually absorbed. | 2012-04-19 |
20120094808 | DOORWAY MOUNTED HORIZONTAL BAR - A doorway mounted horizontal bar includes a rod having two ends for attaching to two side moldings of a doorway, two frames attached to the end portions of the rod for supporting a tubular member, and two auxiliary supports each having a lower segment attached to the rod and each having an upper handle attached to the upper end of the frame for being grasped by the user, the lower segments of the auxiliary supports are each attached to the rod with a coupling device, and the handles of the auxiliary supports are each attached to the frame with another coupling device, the coupling devices each include a quick release fastening device for detachably securing the coupling devices and the auxiliary supports to the rod and the frames. | 2012-04-19 |
20120094809 | ENHANCEMENT OF THE FLOOR OF A GYM'S WEIGHTROOM - A floor of a gym's weight room is configured to encompass the installation of weight stations with weight towers controlled remotely from a control panel, with said weight station assembled atop a weight room floor. The floor of the gym, for each station-tower combination, includes two reinforced boxes embedded in the floor, each having an opening at floor level, wherein one box is located below the base of the weight station and one box is located in front of the respective weight tower, preferably positioned far from the station, the two boxes being connected by at least two parallel tubes located beneath the level of the gym's floor, and wherein the interior of each box is affixed with a cable pulley and bearing, each cable pulley being at a level so that the horizontal section of a steel cable runs toward a center of one of the tubes. | 2012-04-19 |
20120094810 | Barbell Having Decreased Destabilizing Forces And Method For Making Same - A adjustable barbell producing decreased destabilizing forces during the lifting movement, and a method for making same, includes a bar having a pair of longitudinally-separated inner collars weighing no less than approximately 30 lbs, a pair of sleeves mounted for rotation about the longitudinal axis of the bar and sized to accommodate the through-holes of removable weight plates mounted on said sleeves, each sleeve being positioned longitudinally outward of a respective one of said collars, the collars thereby decreasing the stress on the bar and the moment of inertia of the weight being lifted. | 2012-04-19 |
20120094811 | ADJUSTABLE RESISTIVE EXERCISE KIT, APPAREL ITEM AND METHOD OF USING SAME - An exercise kit is disclosed which includes a foundation article of clothing adapted to carry user adjustable resistive means which cooperates with the foundation article of clothing to facilitate the exercise or toning of at least one muscle group of a user. | 2012-04-19 |
20120094812 | EXERCISE BAR HAVING SLIDING HAND GRIPS - An exercise apparatus includes an elongate bar having a medial portion and opposed ends disposed outwardly of the medial portion with a pair of hand grips mounted on the bar in spaced-apart relation and configured to slide along the length of the bar against a resistance force from a first exercise position to a second exercise position. A resistance member fixed to the bar and movably attached to at least one of the hand grips increases the resistance force as the hand grip slides along the bar from the first exercise position to the second exercise position. The resistance member includes inner and outer band attachment mounts spaced-apart along the length of the bar and an elastic band attached to and disposed between the band attachment mounts. A user performs push-up exercises from a prone position and barbell exercises from a supine position or a standing position. | 2012-04-19 |
20120094813 | PHYSICAL EXERCISE APPARATUS - Physical exercise apparatus, comprising a support base, a vertical structure comprising at least one articulated joint, a support frame to which there are coupled a member for association with a user's body, and at least two articulated arms which are connected to said support frame so as to be able to pivot in several directions. | 2012-04-19 |
20120094814 | METHOD AND APPARATUS FOR VIBROTACTILE MOTIONAL TRAINING EMPLOYING COGNITIVE SPATIAL ACTIVITY - A method and apparatus is disclosed for providing motional training, such as treatment of disequilibrium and movement and balance disorders, using cognitive spatial activity and by providing a subject with vibrotactile feedback in response to an attempt to perform the spatial activity. | 2012-04-19 |
20120094815 | Exercise Apparatus with Hooks for Attaching Resistance Bands - This disclosure relates to an exercise apparatus with a plurality of hooks for attaching resistance bands and a method for manufacturing the exercise apparatus. | 2012-04-19 |
20120094816 | METHOD FOR MANUFACTURING A CONTAINER OF PAPER MATERIAL FOR FOOD, FOR EXAMPLE LIQUIDS, IN PARTIUCLAR DRINKS SUCH AS A PAPER GLASS FOR HOT DRINKS - A method has been conceived for the manufacture of containers in paper material for foodstuffs such as drinks, in particular hot drinks, comprising a bottom wall ( | 2012-04-19 |
20120094817 | System For Transferring Tubular Blanks In An Open Configuration To A Supply Line Of A Packing Machine - A system for transferring tubular blanks to a packing machine includes an apparatus intermittently positioned in a zone (Z) situated in front of the line with an open tubular blank ( | 2012-04-19 |
20120094818 | Device For Opening Out Blanks Supplied In A Flattened Tubular Configuration - A device for opening out blanks supplied in a flattened tubular configuration comprises a store ( | 2012-04-19 |
20120094819 | DRAWING APPARATUS AND METHOD OF DRAWING SHEET - A drawing apparatus to draw a sheet includes a first protrusion group aligned in rows along a drawing direction of the sheet; and a second protrusion group aligned in rows along the drawing direction and that meshes with the first protrusion group. The sheet is bitten in between the first and second protrusion groups. A space in which the sheet is bitten with the first protrusion group and the second protrusion group includes a first region, a second region adjacent to the first region, and a third region adjacent to the second region opposite to the first region. A drawing amount of the sheet in the case that the sheet is bitten with the first protrusion group and the second protrusion group in the second region is greater than the drawing amount in the first region and is smaller than the drawing amount in the third region. | 2012-04-19 |
20120094820 | PAPER PRESSING MACHINE FOR SCULPTURED PATTERN - A paper pressing machine for sculptured pattern comprises a bottom plastic sheet ( | 2012-04-19 |
20120094821 | METHOD AND DEVICES FOR PRODUCING OPTICAL GLASS ELEMENTS, PARTICULARLY CONCENTRATOR OPTICS - a method and to an apparatus for producing optical glass elements, in particular for producing what is referred to as low-cost optics for focusing light onto small areas, for example, for photovoltaic applications or optical couplers. The method for producing the optical glass elements includes: providing a glass rod having a selected cross-section, heating the glass rod such that it can be deformed in at least some sections, molding at least one optical glass element from the deformable section using a molding tool, separating the optical glass element from the glass rod at the connection, arranging a plurality of separated optical glass elements to form a group, and grinding and/or polishing at least one section of the separating surfaces of the grouped optical glass elements. The invention makes it possible to produce optical glass elements that meet low quality requirements in high quantities and with high output at low cost. | 2012-04-19 |
20120094822 | Lithium silicate glass ceramic for fabrication of dental appliances - The present invention relates to a method of fabricating an improved lithium silicate glass ceramic and to that material for the manufacture of blocks for dental appliances using a CAD/CAM process and hot pressing system. The lithium silicate material has a chemical composition that is different from those reported in the prior art with 1 to 10% of germanium dioxide in final composition. The softening points are close to the crystallization final temperature of 800° C. indicating that the samples will support the temperature process without shape deformation. | 2012-04-19 |
20120094823 | TRANSPARENT ZIRCONIA SINTERED BODY, METHOD FOR PRODUCING SAME, AND USE OF SAME - The subject of the present invention relates to obtaining a zirconia sintered body having excellent in both properties of a translucency and a mechanical strength. The present invention relates to obtaining a high-strength zirconia sintered body having a translucency of an in-line transmission of 50% or more at a sample thickness of 1 mm for visible light at a wavelength of 600 nm and an average flexural strength of 300 MPa or more by subjecting a zirconia primary sintered body having an average grain size of 1 μm or less and a relative density of 92% or more and the crystal phase composed of cubic crystals only to HIP treatment at a temperature of 1,250° C. to 1,600° C. and a pressure of at least 50 MPa. The primary sintered body is obtained by maintaining a molded body of a zirconia powder containing 7 mol % to 30 mol % of yttria at 1,100° C. to 1,300° C. for at least 5 hrs or by heating the molded body at a high rate of temperature rise of 500° C./hr or more. | 2012-04-19 |
20120094824 | ALUMINUM TITANATE-BASED CERAMICS - The invention is to provide an aluminum titanate-based ceramics showing a good mechanical strength. The invention is an aluminum titanate-based ceramics obtained by firing a starting material mixture which contains a titanium element and an aluminum element, and further contains a chromium element and/or a tungsten element. Preferably, a content of a chromium source which contains the chromium element is from 0.001 to 5 parts by mass, and a content of a tungsten source which contains the tungsten element is from 0.001 to 1.0 part by mass relative to 100 parts by mass of the starting material mixture. | 2012-04-19 |
20120094825 | METHOD FOR PRODUCING ELECTRODE CATALYST - A method for producing an electrode catalyst, comprising a step of calcining a precursor of the electrode catalyst under conditions under which a second material defined below can change into a carbonaceous material, the precursor having been obtained by continuously hydrothermally reacting a mixture containing a first material defined below and the second material defined below in the presence of supercritical or subcritical water, wherein
| 2012-04-19 |
20120094826 | EXHAUST GAS PURIFYING CATALYST - An exhaust gas purifying catalyst includes: a support that contains at least one element that is selected from the first group that consists of Al, Zr and Ce, at least one element that is selected from the second group that consists of Ag, Mn, Co, Cu and Fe, and Ti; and particles that are composed of a metal or oxide of at least one element that is selected from the third group that consists of Ag, Mn, Co, Cu and Fe and that are deposited on the support. Seventy percent or more of any plurality of measurement points with a diameter of 2 nm on a surface of the support are composed of a composite part that has the at least one element selected from the second group content of 0.5 to 10 mol % and has a Ti content of 0.3 mol % or greater. | 2012-04-19 |
20120094827 | EXHAUST GAS-PURIFYING CATALYST AND METHOD OF PRODUCING SAME - The exhaust gas-purifying catalyst includes a first oxide particle with an oxygen storage capacity, one or more second oxide particles partially or entirely covering a surface of the first oxide particle and having an oxygen storage capacity lower than that of the first oxide particle, an average particle diameter D | 2012-04-19 |
20120094828 | HIGH SURFACE AREA CARBON AND PROCESS FOR ITS PRODUCTION - The present invention provides a high surface area porous carbon material and a process for making this material. In particular, the carbon material is derived from biomass and has large mesopore and micropore surfaces that promote improved adsorption of materials and gas storage capabilities. | 2012-04-19 |
20120094829 | Active Compound Combinations Having Insecticidal and Acaricidal Properties - The present invention relates to novel active compound combinations comprising, firstly, at least one known compound of the formula (I) | 2012-04-19 |
20120094830 | ANTHRANILIC ACID DIAMIDE DERIVATIVE WITH HETERO-AROMATIC AND HETERO-CYCLIC SUBSTITUENTS - The present invention relates to new insecticides of the formula (I) | 2012-04-19 |
20120094831 | Chlorella Cells as a Method for Improving Plant Quality - This invention relates to a method of improving plant quality through the foliar application of | 2012-04-19 |
20120094832 | NOVEL HERBICIDES - Compounds of formula (I) wherein the substituents are as defined in claim | 2012-04-19 |
20120094833 | HERBICIDAL QUINOLINE AND 1,8 -NAPHTHYRIDINE COMPOUNDS | 2012-04-19 |
20120094834 | method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure - A method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure, wherein the plants, the plant propagules, the seed of the plants and/or the locus where the plants are growing or are intended to grow are treated with an effective amount of a composition comprising
| 2012-04-19 |
20120094835 | Non-Aqueous Agricultural Compositions - Suggested are new non-aqueous agricultural compositions, comprising (a) biocides and (b) alkoxylation products of unsaturated fatty alcohols. | 2012-04-19 |
20120094836 | Biocide Compositions (III) - Described are agrochemical compositions, comprising (a) amides based on ketocarboxylic acids, and (b) biocides. The compositions are clear and exhibit an improved stability even if stored at temperatures between 5° and 40° C. over a long period of time. | 2012-04-19 |
20120094837 | Novel Heterocyclic Compounds as Pesticides - The present invention relates to novel heterocyclic compounds, to processes for preparation thereof and to the use thereof for controlling animal pests, which include arthropods and especially insects. | 2012-04-19 |
20120094838 | SYSTEMS, METHODS AND APPARATUS FOR DIGITAL-TO-ANALOG CONVERSION OF SUPERCONDUCTING MAGNETIC FLUX SIGNALS - A superconducting flux digital-to-analog converter includes a superconducting inductor ladder circuit. The ladder circuit includes a plurality of closed superconducting current paths that each includes at least two superconducting inductors coupled in series to form a respective superconducting loop, successively adjacent or neighboring superconducting loops are connected in parallel with each other and share at least one of the superconducting inductors to form a flux divider network. A data signal input structure provides a respective bit of a multiple bit signal to each of the superconducting loops. The data signal input structure may include a set of superconducting quantum interference devices (SQUIDs). The data signal input structure may include a superconducting shift register, for example a single-flux quantum (SFQ) shift register or a flux-based superconducting shift register comprising a number of latching qubits. | 2012-04-19 |
20120094839 | NIOBIUM BASED SUPERCONDUCTING RADIO FREQUENCY(SCRF) CAVITIES COMPRISING NIOBIUM COMPONENTS JOINED BY LASER WELDING, METHOD AND APPARATUS FOR MANUFACTURING SUCH CAVITIES - Niobium or its alloy based Superconducting Radio Frequency (SCRF) Cavities involving atleast one laser beam welded components in the SCRF cavity welded from inside surface of the wall of cavity directed to achieving more than half the thickness to full depth penetration with minimum HAZ, minimizing distortion and shrinkage. The method ensures improved weld quality and surface finish substantially free of any weld defects. Also disclosed is the welding nozzle system and welding rigs adapted to facilitate such laser welding of the Niobium or its alloy based Superconducting Radio Frequency (SCRF) Cavities. The invention is thus directed to enhancing productivity, ensuring consistent quality and reliability, enhanced weld penetration with minimum HAZ, smooth finish of weld joints at possible reduced costs. | 2012-04-19 |
20120094840 | REFRIGERATOR COOLING-TYPE SUPERCONDUCTING MAGNET - Magnetic field attenuation in a persistent current mode operation is prevented, heat generation at a connecting part between the persistent current switch and the superconducting coil, and increase in a cooling temperature of the superconducting coil in a current supplying mode is suppressed to a minimum. | 2012-04-19 |
20120094841 | METHOD OF PREPARING MgB2 SUPERCONDUCTING WIRE AND THE MgB2 SUPERCONDUCTING WIRE PREPARED THEREBY - Disclosed herein is a method of preparing a MgB | 2012-04-19 |
20120094842 | METHODS OF ASSESSING AND TREATING PULMONARY DISEASE - Methods of diagnosing risk of pulmonary disease in a mammal with cystic fibrosis are provided comprising screening a biological sample obtained from the mammal for MBL2 or SP-A1 deficiency, and TGFB1 over-expression. | 2012-04-19 |
20120094843 | DETECTING AND TREATING BREAST CANCER RESISTANCE TO EGFR INHIBITORS - The application describes therapeutic compositions and methods for treating cancer. For example, therapeutic compositions and methods related to inhibition of FAM83A (family with sequence similarity 83) are provided. The application also describes methods for diagnosing cancer resistance to EGFR inhibitors. For example, a method of diagnosing cancer resistance to EGFR inhibitors by detecting increased FAM83A levels is described. | 2012-04-19 |
20120094844 | GENETIC VARIANTS IN IL-6, P53, MMP-9 AND CXCR PREDICT CLINICAL OUTCOME IN PATIENTS WITH CANCER - The invention provides compositions and methods for determining the likelihood of response or survival of cancer patients treated with anti-VEGF therapy. After determining if a patient is likely to be successfully treated, the invention also provides methods for treating the patients. | 2012-04-19 |
20120094845 | METHODS AND DEVICES FOR ASSESSING INFERTILITY AND/OR EGG QUALITY - The invention generally relates to methods and devices for assessing infertility. In certain embodiments, methods of the invention involve conducting an assay to determine presence or absence of a mutation in a plurality of genes selected from Table 1, and assessing infertility based on results of the assay, wherein presence of a mutation in at least two of the genes from Table 1 is indicative of infertility. | 2012-04-19 |
20120094846 | METHOD FOR DETECTING CYSTIC FIBROSIS - The present invention relates to methods for amplifying various regions of the cystic fibrosis transmembrane regulator (CFTR) gene. Methods are provided for amplifying one or all 27 exons of the CFTR gene and a portion of the CFTR promoter region in a single tube. The method can identify the presence or absence of CF deletions or insertions in a sample and assist in the diagnosis of a genetic predisposition to cystic fibrosis. | 2012-04-19 |
20120094847 | THE USE OF CLASS IIB RESTRICTION ENDONUCLEASES IN 2ND GENERATION SEQUENCING APPLICATIONS - The present invention relates to a method for genotyping DNA molecules contained in at least one DNA sample comprising: (a) digesting the DNA molecules contained in at least one DNA sample with a class IIB restriction endonuclease to generate DNA fragments; (b) optionally separating DNA fragments comprising the recognition site for said class IIB restriction endonuclease from the remaining DNA fragments; (c) attaching at least one adaptor DNA to the 5′ and/or 3′ end of one or both strands of the DNA fragments comprising the recognition site for said class IIB restriction endonuclease obtained in a) or separated in b) to form adaptor-fragment constructs; (d) determining the sequence of at least a fraction of the DNA fragments obtained in c); and (e) assigning genotypes to said at least one DNA sample analysed based on the sequence data obtained in d). The present invention further relates to method for determining the position of DNA molecules comprised in a DNA library within the DNA sequence represented by said DNA library or within a known DNA sequence and for establishing a cross-reference between individual DNA molecules and their location in an at least three dimensional matrix. | 2012-04-19 |
20120094848 | Method for pairwise sequencing of target polynucleotides - The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. Using the methods of the invention it is possible to obtain two linked or paired reads of sequence information from each double-stranded template on a clustered array, rather than just a single sequencing read from one strand of the template. | 2012-04-19 |
20120094849 | METHOD FOR DETERMINING COPY NUMBER VARIATIONS - The invention provides a method for determining copy number variations (CNV) of a sequence of interest in a test sample that comprises a mixture of nucleic acids that are known or are suspected to differ in the amount of one or more sequence of interest. The method comprises a statistical approach that accounts for accrued variability stemming from process-related, interchromosomal and inter-sequencing variability. The method is applicable to determining CNV of any fetal aneuploidy, and CNVs known or suspected to be associated with a variety of medical conditions. | 2012-04-19 |
20120094850 | METHOD FOR DETERMINING THE ORIGIN OF A SAMPLE - A method for determining the nature of a sample is provided, wherein the presence or absence of at least one marker small non-coding RNA in the sample is detected. Suitable marker small non-coding RNAs for different samples such as blood, saliva, semen and vaginal secretions are provided. Also provided are suitable kits and methods for identifying marker small-non coding RNAs. | 2012-04-19 |
20120094851 | Multi-through Hole Testing Plate for High Throughput Screening - A method for holding samples for analysis and an apparatus thereof includes a testing plate with a pair of opposing surfaces and a plurality of holes. Each of the holes extends from one of the opposing surfaces to the other one of the opposing surfaces. The holes are arranged in groups, where each group has at least two rows and two columns of holes. The groups are arranged in sets, where each set has at least two rows and two columns of groups. To analyze samples, at least one of the opposing surfaces of the testing plate is immersed in a solution to be analyzed. A portion of the solution enters openings for each of the holes in the immersed opposing surface. Once the holes are filled with solution, the testing plate is removed and is held above a supporting surface. Surface tension holds the solution in each of the holes. The solution in one or more of the holes is then analyzed and the solution in one of these holes is identified for further study. The location of the identified solution is marked based upon its location within a particular set and group of holes. | 2012-04-19 |
20120094852 | MAGNETIC NANOPARTICLE DETECTION ACROSS A MEMBRANE - Magnetic nanoparticles are detected across a thin membrane that separates the nanoparticles from a magnetic sensor. The technique can be used in a medical context, in which an analyte of interest (present in a test fluid, such as blood) is attached to the membrane. Other compounds are in turn bound to the analyte, with one of these compounds including a magnetic nanoparticle that is then detected by the sensor. In this way, the analyte is detected by detecting the magnetic nanoparticle. By counting the number of magnetic nanoparticles, the concentration of the analyte in the test fluid can be determined. | 2012-04-19 |
20120094853 | COMPOSITIONS AND METHODS FOR PREDICTION OF DRUG SENSITIVITY, RESISTANCE, AND DISEASE PROGRESSION - The present invention is based on the discovery that functional stratification and/or signaling profiles can be used for diagnosing disease status, determining drug resistance or sensitivity of cancer cells, monitoring a disease or responsiveness to a therapeutic agent, and/or predicting a therapeutic outcome for a subject. Provided herein are assays for diagnosis and/or prognosis of diseases in patients. Also provided are compositions and methods that evaluate the resistance or sensitivity of diseases to targeted therapeutic agents prior to initiation of the therapeutic regimen and to monitor the therapeutic effects of the therapeutic regimen. Also provided are methods for determining the difference between a basal level or state of a molecule in a sample and the level or state of the molecule after stimulation of a portion of the live sample with a modulator ex vivo, wherein the difference is expressed as a value which is indicative of the presence, absence or risk of having a disease. The methods of the invention may also be used for predicting the effect of an agent on the disease and monitoring the course of a subject's therapy. | 2012-04-19 |
20120094854 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PSYCHOTIC DISORDERS THROUGH THE IDENTIFICATION OF THE OLANZAPINE POOR RESPONSE PREDICTOR GENE SIGNATURE - Methods and compositions relate to genetic markers of psychotic disorders, e.g., schizophrenia (SZ), are provided. For example, in certain aspects methods for determinations of a OPRP genetic signature are described. Furthermore, the invention provides methods and compositions involving treatment of psychotic disorders using the genetic signature. | 2012-04-19 |
20120094855 | MEANS AND METHODS FOR DIAGNOSING PREDISPOSITION FOR TREATMENT EMERGENT SUICIDAL IDEATION (TESI) - This invention relates to a method of diagnosing a predisposition for or the occurrence of treatment emergent suicidal ideation in an individual, the method comprising determining the presence or absence of one, more or all SNPs selected from the SNPs defined by SEQ ID NOs: 8, 18, 19, 47, 50, 52, 56, 64, 73, 86, 87, 92, 94, 95, 97 and 99. | 2012-04-19 |
20120094856 | METHOD FOR DETECTING AN ANALYTE IN A SAMPLE BY MULTIPLEXING FRET ANALYSIS AND KIT - The invention concerns a method for detecting an analyte in a sample by multiplexing FRET (Förster Resonance Energy Transfer) analysis, the method comprising the following steps: providing a sample containing an energy transfer donor, several spectrally different quantum dot species, and an analyte, wherein the analyte is configured to mediate an energy transfer within a first energy transfer donor-acceptor pair provided by the energy transfer donor and a first quantum dot specie, the energy transfer donor is configured to act as energy transfer donor in the first energy transfer donor-acceptor pair, and the first quantum dot specie is configured to act as energy transfer acceptor in the first energy transfer donor-acceptor pair, irradiating excitation light from an excitation light source to the sample, in the first energy transfer donor-acceptor pair, transferring excitation energy from the energy transfer donor excited by the excitation light to the first quantum dot specie, the energy transfer being mediated by the analyte, and detecting emission light emitted by the first quantum dot specie after receiving the excitation energy. | 2012-04-19 |
20120094857 | Methods of Subclassification of Ductal Carcinoma of the Breast - Provided herein are methods of determining the aggressiveness or indolence of a ductal carcinoma in situ lesion. Also provided are methods of developing treatment plans for subjects with a ductal carcinoma in situ lesion based on the aggressiveness of the lesion. | 2012-04-19 |
20120094858 | BIOMARKERS - The invention relates to a method of diagnosing or monitoring bipolar disorders, in particular bipolar I and bipolar II disorders, such as manic psychosis. | 2012-04-19 |
20120094859 | METHODS FOR DETECTION OF DEPRESSIVE DISORDERS - The present invention relates generally to the detection or diagnosis of depressive disorders, and provides methods and compositions useful for this purpose. In particular, the present invention provides biomarkers for the detection or diagnosis of major depressive disorder, and methods of use thereof. | 2012-04-19 |
20120094860 | Compositions, Antibodies, Asthma Diagnosis Methods, and Methods for Preparing Antibodies - Methods for preparing an antibody are provided with the method including incorporating 3-bromo-4-hydroxy-benzoic acid into a protein to form an antigen, immunizing a mammalian host with the antigen, and recovering an antibody having an affinity for the antigen from the host. Antibodies having a binding affinity for a monohalotyrosine are provided as well as composition comprising an antibody bound with monohalotyrosine. Compositions comprising a protein having a 3-bromo-4-hydroxy-benzoic acid moiety are also provided. Methods for evaluating the severity of asthma are provide with the methods including analyzing sputum of a patient using an antibody having a binding affinity for monohalotyrosine, and measuring the amount of antibody bound to protein. Methods for determining eosinophil activity in bodily fluid are also provided with the methods including exposing bodily fluid to an antibody having a binding affinity for monohalotyrosine, and measuring the amount of bound antibody to determine the eosinophil activity. | 2012-04-19 |
20120094861 | Compositions and Methods for Determining Immune Status - The present invention provides compositions and methods for identifying molecules in samples that bind to molecules associated with pathogenic agents (e.g., infectious agents). In certain aspects, the invention may be used to identify individuals that have been exposed to one or more pathogenic agent or have generated antibodies in response to one or more pathogenic agent. In other aspects, the invention is directed to the identification of molecules of one or more pathogenic agent that may be used to generate immune responses in other individuals. | 2012-04-19 |
20120094862 | CLASS II HUMAN HISTONE DEACETYLASES, AND USES RELATED THERETO - The invention provides histone deacetylase class II nucleic acids and polypeptides, methods and reagents for their use, and related compounds including small molecule libraries containing class II histone deacetylase inhibitors. | 2012-04-19 |
20120094863 | BIOMARKERS AND METHODS FOR DETERMINING EFFICACY OF ANTI-EGFR ANTIBODIES IN CANCER THERAPY - The invention relates to biomarkers based on gene expression products and methods for determining the efficacy of anti-EGFR antibodies in the treatment of EGFR expressing cancer. The invention is further related to the prediction of sensitivity or resistance of a patient suffering from EGFR expressing cancer to the treatment of said patient with a specific anti-EGFR antibody. The invention is preferably related to the identification of respective biomarkers that allow a better prediction of the clinical outcome of the treatment with anti-EGFR antibodies in patients with KRAS wild-type tumors. In this context, the invention especially relates to anti-EFGR antibody c225/cetuximab (Erbitux®) and its use in patients suffering from colorectal Cancer (CRC). | 2012-04-19 |
20120094864 | EXTRACELLULAR ALLOSTERIC INHIBITOR BINDING DOMAIN FROM A TYROSINE KINASE RECEPTOR - The present invention relates to an extracellular binding domain for an allosteric inhibitor, whereby said binding domain is derived from a single membrane span tyrosine kinase receptor. More specifically, the invention relates to an extracellular domain derived from a Fibroblast Growth Factor Receptor (FGFR). It further relates to the use of this domain for the identification of similar domains in the extracellular part of other tyrosine kinase receptors, and to a screening method for identification of a small compound allosteric inhibitor. | 2012-04-19 |
20120094865 | Method for Stimulating Antigen-Specific T Cell Responses Using Accelerated Co-Cultured Dendritic Cells - The invention relates to a method for stimulating antigen-specific T cell responses by using accelerated co-cultured dendritic cells, and to uses thereof, such as a method for diagnosing a disease and a method for producing isolated T cell clones displaying specific immunological properties. | 2012-04-19 |
20120094866 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 2012-04-19 |
20120094867 | High-Throughput Molecular Rotor Viscometry Assay - Described are compositions and methods related to determining the rate of viscosity change in a suspension in real time. The compositions and methods have a broad range of applications, including the measurement of amylase-mediated liquefaction of a starch suspension. | 2012-04-19 |
20120094868 | DETECTION OF CIRCULATING TUMOR CELLS IN PERIPHERAL BLOOD WITH AN AUTOMATED SCANNING FLUORESCENCE MICROSCOPE - An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids. | 2012-04-19 |
20120094869 | MICROPLATE ASSAY KIT - The present invention provides a microplate-based assay kit that incorporates all assay reagents and standards in a simple and efficient format and may be used in biochemical assays. The assay kit includes pre-filled, pre-sealed and barcoded microplates with a standard physical footprint for use in a microplate-based automated analyzer system which enables simple and efficient operation by an unskilled user via per-use factory-sealed and barcoded reagent and calibrator microplates. Such microplates allow the user to run a broad test menu without the need to monitor the arrangement and supply of internally stored reagents and standards, thus greatly simplifying the user experience and eliminating the need for highly skilled users. | 2012-04-19 |
20120094870 | Library of a Collection of Cells - The present invention relates to combinatorial gene expression libraries and methods for making these. Such libraries are useful in discovery of novel and/or enhanced metabolic pathways leading to the production of novel compounds for e.g., drug discovery and/or to the prosecution of known compounds in novel quantities or in novel compartments of the cells. The expression libraries in particular are composed of host cells capable of co-ordinated and controllable expression of large numbers of heterologous genes in the host cells. | 2012-04-19 |
20120094871 | Particle Population and Methods of Making and Using - The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their volumes for higher loading capacities than those achievable solely with surface attachment. In one aspect, nucleic acid polymer particles of the invention comprise polyacrylamide particles with uniform size distributions having low coefficients of variations, which result in reduced particle-to-particle variation in analytical assays. Such particle compositions are used in various amplification reactions to make amplicon libraries from nucleic acid fragment libraries. | 2012-04-19 |
20120094872 | SILANE MIXTURES - Silanation compositions containing a mixture of two or more silanation reagents, where at least one silanation reagent includes a functional group capable of supporting polymer synthesis and at least one silanation reagent includes no functional group capable of supporting polymer synthesis are useful in modulating the active site density and hydrolytic stability of a surface. These compositions are particularly useful in silanating a surface prior to preparation of a polymer array and provide for increased hybridization results. | 2012-04-19 |
20120094873 | COMBINATORIAL LIBRARIES OF PROTEINS HAVING THE SCAFFOLD STRUCTURE OF C-TYPE LECTIN-LIKE DOMAINS - Novel polypeptides having the scaffold structure of a C-type lectin-like domain (CTLD) and a randomized loop region for specifically binding a variety of target compounds and also provides nucleic acids encoding the polypeptides. Combinatorial CTLD libraries, methods for constructing the libraries, and methods for screening the libraries to identify and isolate the novel CTLD polypeptides. Libraries of nucleic acids encoding polypeptides having a scaffold CTLD with a randomized loop region, as well as nucleic acid sequences, vectors, and methods for preparing and expressing the libraries. Exemplary nucleic acids useful in the combinatorial libraries are derived from tetranectin and other proteins having a CTLD. | 2012-04-19 |