16th week of 2010 patent applcation highlights part 11 |
Patent application number | Title | Published |
20100099557 | Thermosensitive Recording Medium - The present invention provides a thermosensitive recording medium, which is excellent in stamping ability, anti-scratching ability, and water and plasticizer resistance of image area as well as in recording sensitivity, image quality and storage stability. The present invention is a thermosensitive recording medium having a thermosensitive recording layer containing at least a colorless or pale colored basic leuco dye and an electron accepting developing agent as a coating layer on a substrate, wherein at least an outermost layer among the thermosensitive recording layer and other optionally prepared coated layers contains powdered cellulose, wherein the powdered cellulose is prepared by a dry grinding process at ambient temperature. The thermosensitive recording medium preferably contains a condensate composition comprising 2,2′-methylenebis(4-t-butylphenol) as an electron accepting developing agent, and a cross-linked diphenylsulfone compound such as 2,2′-bis[4-(4-hydroxyphenylsulfone) phenoxy]diphenylether as a stabilizer. | 2010-04-22 |
20100099558 | DIHALOPHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES - The present invention relates to dihalophenoxyphenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to a composition for this purpose, comprising the phenoxyamidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat. | 2010-04-22 |
20100099559 | Method for protecting soybeans from being infected by fungi - Method for protecting soybean plants from being infected by harmful fungi, wherein the soybean plants, their seed or the soil is treated with a fungicidal effective amount of a synergistically active combination comprising a) N-(2-bicycloprop-2-ylphenyl)-3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxamide (I) or 3-(difluoromethyl)-1-methyl-N-[1,2,3,4-tetrahydro-9-(1-methylethyl)-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide (II) and b) epoxiconazole or metconazole; a fungicidal agent and seed comprising said combination. | 2010-04-22 |
20100099560 | Methods and Compositions for Increasing the Amounts of Phosphorus Available for Plant Uptake from Soils - The present invention relates to a method of enhancing growth conditions for plants by growing the plants in soil containing, in proximity to the plant roots, both a phosphorus source and at least two strains of the fungus | 2010-04-22 |
20100099561 | HETEROBICYCLIC ALKYLTHIO-BRIDGED ISOXAZOLINES - Disclosed are compounds of Formula 1, N-oxides, and salts thereof, | 2010-04-22 |
20100099562 | HERBICIDE COMBINATION - The present invention relates to a herbicide combination comprising components (A) and (B), where | 2010-04-22 |
20100099563 | HERBICIDAL COMPOSITIONS CONTAINING BENZOYLPYRAZOLE COMPOUNDS - To provide a herbicidal composition which can be applied at a low dose as compared with individual application, and thus is effective to reduce the environmental load on a place where the composition is applied or a periphery thereof, of which the herbicidal spectrum is enlarged, and of which the herbicidal effects last over a long period of time. | 2010-04-22 |
20100099564 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES - Herbicide combination of dimethoxytriazinyl-substituted difluoromethanesulfonylanilides, wherein the combination comprises: (A) at least one (sulfon)amide herbicide; and (B) at least one compound, or salts thereof, described by the general formula (I): | 2010-04-22 |
20100099565 | STORAGE-STABLE COMPOSITIONS CONTAINING HYDROGEN CYANAMIDE AND PROPIONIC ACID - An aqueous storage-stable composition comprises from about 10 to about 35% by weight hydrogen cyanamide, from about 3 to about 25% by weight propionic acid, potassium propionate or ammonium propionate, and water, and has a pH of from about 2.5 to about 4, wherein the concentration of hydrogen cyanamide is greater than the concentration of propionic acid. | 2010-04-22 |
20100099566 | Agriculture actives delivery composition comprising boron and persulfate ion-crosslinked polyvinyl alcohol microcapsules and method of use thereof - An aqueous composition is provided having a pH of from about 2.0 to about 12.8 and comprising boron or persulfate ion-crosslinked polyvinyl alcohol microcapsules. A method of delivering an agriculture active to a substrate is further provided comprising applying to the substrate an aqueous composition comprised of agriculture active containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules, as well as a method of treating a substrate to protect from pests or promote crop growth comprising applying to the substrate an aqueous treating composition comprised of agriculture active containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules. | 2010-04-22 |
20100099567 | GROWTH REGULATORS FOR GRAMINEOUS WEEDS - The invention provides a growth regulator for gramineous weeds, particularly those growing in turf, which comprises, as an active ingredient, cytokinin and/or an ethylene-producing substance in combination with cytokinin; and a method for regulating the growth of gramineous weeds with the relevant growth regulator more economically with ease. | 2010-04-22 |
20100099568 | Heteroaroyl-Substituted Serine Amides - The present invention relates to heteroaroyl-substituted serinamides of the formula (I) | 2010-04-22 |
20100099569 | ADJUVANT COMPOSITION, AGROCHEMICAL SPRAY AQUEOUS SOLUTION CONTAINING THE SAME AND CONTROL METHOD USING THE SAME - The present invention relates to an adjuvant composition characterized by containing the following (A) and (B):
| 2010-04-22 |
20100099570 | SUPERCONDUCTOR CABLE - Superconductor cable having a plurality of flat, tape-shaped ribbon superconductor wires assembled to form a stack having a rectangular cross section, the stack having a twist about a longitudinal axis of the stack. Multiple superconductor cables including twisted stacked-cables of the flat-tape-shaped superconductor wires, and power cable comprising the twisted flat-tape stacked cables are disclosed. Superconducting power cable disposed within and separated from an electrical insulator with a space passing cryo-coolant between the superconducting cable and insulator is also disclosed. | 2010-04-22 |
20100099571 | Superconducting cable - A superconducting cable ( | 2010-04-22 |
20100099572 | SUPERCONDUCTING POWER CABLE CAPABLE OF QUENCH DETECTION AND QUENCH DETECTION SYSTEM USING THE SAME - Disclosed is a superconducting power cable capable of quench detection, and a quench detection system using the superconducting power cable. The superconducting power cable capable of quench detection includes a former; a superconducting conductor layer composed of a superconducting wire and surrounding the former; a conductor layer quench detection coil interposed between the former and the superconducting conductor layer and surrounding the former; an insulating layer surrounding the superconducting conductor layer; and a shielding layer surrounding the insulating layer. This superconducting power cable may detect quench generated during its operation in real time. | 2010-04-22 |
20100099573 | RARE EARTH-TYPE TAPE-SHAPED OXIDE SUPERCONDUCTOR AND A COMPOSITE SUBSTRATE USED FOR THE SAME - This invention provides a rare earth-type tape-shaped oxide superconductor having excellent mechanical strength and superconducting properties and a composite substrate using for the same. Non-oriented and non-magnetic Ni-9 at % W alloy tapes ( | 2010-04-22 |
20100099574 | METHODS OF IDENTIFYING AN ANALYTE AND NUCLEIC ACID ANALYSIS - A method of identifying an analyte. The method includes providing a plurality of microparticles. The microparticles have optically detectable codes extending along bodies of the corresponding microparticle. The microparticles have the chemical probes attached thereto. Each of the chemical probes is associated with a corresponding one of the codes. The method also includes selectively binding target analytes to the chemical probes on the microparticles to produce labeled microparticles and distributing the labeled microparticles to random locations of a substrate. The method also includes determining the codes for the labeled microparticles in the random array and code positions of the codes in the random array. The method further includes detecting the label on the labeled microparticles in the random array and label positions of the labels in the random array. The method also includes using the code positions and the label positions to analyze the target analyte. | 2010-04-22 |
20100099575 | NOVEL POLYPEPTIDE SCAFFOLDS AND USE THEREOF - Novel peptide having a sequence according to SEQ. ID. No. 1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 are disclosed and also polypeptide scaffold consisting of a four helix bundle formed of two dimerized helix-loop-helix motifs, said helix-loop-helix motifs having sequences according to SEQ. ID. No. 1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 which may comprise a fluorescent probe at the side chain of Lys15 and a ligand with affinity for a target molecule at the side chain of Lys8 or Lys34. | 2010-04-22 |
20100099576 | SKIN SUBSTITUTES WITH IMPROVED BARRIER FUNCTION - The present invention relates to in vitro cultured skin substitutes, and in particular to in vitro cultured skin substitutes that have improved barrier function. In some embodiments, improved barrier function is a result of improved culture conditions, while in other embodiments, improved barrier function results from genetic modification of keratinocytes. Improved culture conditions to improve barrier function include organotypic culture in the presence of linoleic acid and/or linoleic acid at about 75% humidity. Suitable genetic modifications for improving barrier function includes transfection with a DNA construct capable of expressing GKLF. | 2010-04-22 |
20100099577 | METHOD OF DETECTING PATHOGENIC LEGIONELLA STRAINS - The invention relates to a method of detecting pathogenic | 2010-04-22 |
20100099578 | siRNA Targeting Fructose-1, 6-bisphosphatase 1 (FBP1) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for FBP1. | 2010-04-22 |
20100099579 | NON-FOULING POLYMERIC SURFACE MODIFICATION AND SIGNAL AMPLIFICATION METHOD FOR BIOMOLECULAR DETECTION - An article such as a biosensor having a nonfouling surface thereon is described. The article comprises: (a) a substrate having a surface portion; (b) a linking layer on the surface portion; (c) a polymer layer comprising brush molecules formed on the linking layer; and (d) optionally but preferably, a first member of a specific binding pair (e.g., a protein, peptide, antibody, nucleic acid, etc.) coupled to the brush molecules. The polymer layer is preferably formed by the process of surface-initiated polymerization (SIP) of monomeric units thereon. Preferably, each of the monomeric units comprises a monomer (for example, a vinyl monomer) core group having at least one protein-resistant head group coupled thereto, to thereby form the brush molecule on the surface portion. Methods of using the articles are also described. | 2010-04-22 |
20100099580 | Photochemical methods and photoactive compounds for modifying surfaces - Compounds and methods for controlling the surface properties are described. Compounds of the invention can form radicals upon exposure to irradiation, which can then react with nearby molecules to alter the surface properties of various substrates. The invention can provide surfaces that are resistant to dewetting, surfaces that have immobilized molecules such as carbohydrates and polymers immobilized, and surfaces that have metals deposited on the surface. The invention can be utilized in a wide range of application, such as sensors, microreactors, microarrays, electroless deposition of metals, and the like. | 2010-04-22 |
20100099581 | LOCALIZED TEMPERATURE CONTROL FOR SPATIAL ARRAYS OF REACTION MEDIA - Individual temperature control in multiple reactions performed simultaneously in a spatial array such as a multi-well plate is achieved by thermoelectric modules with individual control, with each module supplying heat to or drawing heat from a single region within the array, the region containing either a single reaction vessel or a group of reaction vessels. | 2010-04-22 |
20100099582 | Biochip Package Structure - A biochip package structure is provided. The biochip package structure includes a substrate, a biochip, at least one wire, and a molding compound. The substrate has a circuit unit electrically connected, by wiring, to the biochip defined with a sensing region. The molding compound covers the wire but leaves the sensing region of the biochip exposed, allowing a cavity to be formed in the sensing region. The cavity delivers a biomedical sample. The biomedical sample reacts in the sensing region. Thus, the biochip package structure is applicable to various medical and biochemical assays. | 2010-04-22 |
20100099583 | OPTICAL DETECTING APPARATUS FOR A BIO-CHIP - An optical detecting apparatus for a bio-chip, the optical detecting apparatus including: a light source system for illuminating a bio-chip with an excitation light; a fluorescent light detecting system for detecting a fluorescent light emitted by the bio-chip; and a light path altering unit for directing the excitation light emitted by the light source system to a bio-chip and directing the fluorescent light emitted by the bio-chip to the fluorescent light detecting system, wherein a cross-sectional area of the excitation light irradiated by the light source system onto the bio-chip is greater than an area of the bio-chip, and the fluorescent light detecting system detects a fluorescent image of the entire bio-chip with a single illumination of excitation light. | 2010-04-22 |
20100099584 | MUTUAL SOLVENT SYSTEM AND METHOD FOR IMPROVED OIL AND GAS PERMEABILITY IN HIGH TEMPERATURE FORMATIONS - A method of acidizing and cleaning up a formation is disclosed, the formation being above 150 degrees C. The formation is treated with a mutual solvent system comprising a mutual solvent of oil and water, an aqueous acid, a corrosion inhibitor, and an iron control agent. In some embodiments, the iron control agent is present in an amount of less than 1% by weight of the mutual solvent system. In some embodiments, the corrosion inhibitor may be present in an amount of less than 10% by weight of the mutual solvent system. In some embodiments, the mutual solvent system further comprises an intensifier. | 2010-04-22 |
20100099585 | AQUEOUS BASE WELLBORE FLUIDS FOR HIGH TEMPERATURE-HIGH PRESSURE APPLICATIONS AND METHODS OF USE - Embodiments disclosed herein related to an aqueous based well bore fluid that includes at least one ionized polymer, at least one non-ionic polymer, a non-magnetic weighting agent, and an aqueous base fluid. | 2010-04-22 |
20100099586 | BORON CROSSLINKERS FOR FRACTURING FLUIDS WITH APPRECIABLY LOWER POLYMER LOADING - Fracturing fluid compositions and methods of fracturing subterranean formations using polyboronic compounds as crosslinking agents are provided. The compositions and methods of the present invention allow for lower polymer loadings because achieving higher fracturing fluid viscosities can be achieved using less polymer than in traditional crosslinked systems. | 2010-04-22 |
20100099587 | CARBOXYLIC ACID AND OXIDIZER CLEAN-UP COMPOSITIONS AND ASSOCIATED METHODS OF USE IN SUBTERRANEAN APPLICATIONS - Of the many methods provided herein, one method of reducing the viscosity of a viscosified treatment fluid includes: providing a clean-up composition comprising a carboxylic acid; providing a chlorite-based breaker system; providing a viscosified treatment fluid; placing the viscosified treatment fluid in a subterranean formation via a well bore penetrating the subterranean formation; contacting the viscosified treatment fluid with the clean-up composition; contacting the viscosified treatment fluid with the chlorite-based breaker; and allowing the viscosity of the viscosified treatment fluid to reduce. Also provided herein are methods that include a method of reducing polymeric residue from a subterranean formation that includes: placing a clean-up composition and a chlorite-based breaker system in a subterranean formation in contact with an amount of polymeric residue; and allowing the amount of polymeric residue present in the formation to be reduced. | 2010-04-22 |
20100099588 | Dispersant Combination for Improved Transmission Fluids - A lubricant composition of an oil, a dispersant viscosity modifier of a poly(meth)acrylate copolymer having a nitrogen-containing monomer in an amount to provide at least about 0.4 percent by weight nitrogen to the copolymer, and a succinimide dispersant prepared in the substantial absence of chlorine gives good performance as a transmission fluid. | 2010-04-22 |
20100099589 | Lubricating composition with good oxidative stability and reduced deposit formation - A lubricant composition that is particularly suited for use in steam and gas turbine oils and in circulating oils has a balance of excellent oxidative stability and reduced sludge formation and comprises a blended mixture of alkylated phenyl-α-naphthylamine and at least oil soluble triazole or triazole derivative in an oil of lubricating viscosity, such compositions being capable of a residual RPVOT of 25% after at least 500 hours test duration test duration 120° C. in Dry TOST test or, alternatively 50% after 700 hours or 25% after 1000 hours. | 2010-04-22 |
20100099590 | Oil dispersible polymer nanoparticles - There is disclosed an oil-dispersible nanoparticle comprising metal-binding functional groups on its surface. Preferably, the nanoparticle is derived from substantially spherical polymer micelles of (A | 2010-04-22 |
20100099591 | LUBRICATION METHODS - A method of lubricating a two-stroke, diesel crosshead engine comprises lubricating the engine with a cylinder oil and with a system oil, which oils are different from each other, in which the system oil is an SAE 20 or SAE 30 oil, has a total base number of at least 10 mg KOH/g and comprises: (a) a base oil; (b) at least one detergent additive in a total amount of detergent corresponding in performance, as measured by the Hot Filtration Test, to at least 1.5% by weight of the system oil, of a calcium alkyl salicylate detergent soap in which the alkyl group is a C | 2010-04-22 |
20100099592 | PROCESS AND APPARATUS FOR PREPARING A UREA GREASE - The invention provides for a process for preparing a urea grease including: (a) introducing a first feed component to a first feeding zone; (b) introducing a second feed component to a second feeding zone; (c) first reacting-mixing in a first reacting-mixing zone; and (d) cooling-mixing in a cooling-mixing zone. The invention also provides for a process for preparing a urea grease including: (a) introducing a first feed component to a first feeding zone; (b) introducing a second feed component to a second feeding zone; (c) first reacting-mixing in a first reacting-mixing zone; (d) introducing a third feed component to a third feeding zone; (e) second reacting-mixing in a second reacting-mixing zone; and (f) cooling-mixing in a cooling-mixing zone. The invention also provides for an apparatus for preparing a urea grease comprising: (a) a first feeding zone; (b) a second feeding zone; (c) a first reacting-mixing zone; and (d) a cooling-mixing zone. The invention also provides for an apparatus for preparing a urea grease comprising: (a) a first feeding zone; (b) a second feeding zone; (c) a first reacting-mixing zone; (d) a third feeding zone; (e) a second reacting-mixing zone; and (f) a cooling-mixing zone. | 2010-04-22 |
20100099593 | Additive Concentrate and a Method of Lubricating Transmissions - The present invention relates to an additive concentrate comprising a friction modifier, a corrosion inhibitor, and an oil of lubricating viscosity. The invention further provides a method for lubricating a transmission using the additive concentrate. | 2010-04-22 |
20100099594 | Fragrance-delivery composition comprising boron and persulfate ion-crosslinked polyvinyl alcohol microcapsules and method of use thereof - An aqueous composition is provided having a pH of from about 2.0 to about 5.7 to about 12.8 and comprising boron or persulfate ion-crosslinked polyvinyl alcohol microcapsules. A method of delivering a fragrance to a substrate is further provided comprising applying to the substrate an aqueous composition comprised of fragrance-containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules, as well as a method of cleaning a substrate comprising applying to the substrate an aqueous composition comprised of fragrance-containing, boron or persulfate ion-crosslinked, polyvinyl alcohol microcapsules together with at least one cleaning component. | 2010-04-22 |
20100099595 | MANUFACTURING AND CLEANSING OF THIN FILM TRANSISTOR PANELS - A manufacturing a thin film transistor array panel includes depositing a first thin film including aluminum on a substrate, patterning the first thin film by photolithography and etching, cleansing the substrate including the first thin film, and depositing a second thin film on the cleansed substrate. The cleansing is performed using a cleansing material including ultrapure water, cyclic amine, pyrogallol, benzotrizole, and methyl glycol. The cleansing material includes ultrapure water at about 85 wt % to about 99 wt %, cyclic amine at about 0.01 wt % to about 1.0 wt %, pyrogallol at about 0.01 wt % to 1.0 wt %, benzotrizole at about 0.01 wt % to 1.0 wt %, and methyl glycol at about 0.01 wt % to 1.0 wt %. | 2010-04-22 |
20100099596 | Method and composition to remove iron and iron sulfide compounds from pipeline networks - The present invention comprises an iron complexing mixture and method of using same wherein beneficial performance and natural gas pipeline cleaning methods are employed. The synergistic improvement of combining two water-soluble metal complexing agents, THPS and IDS, prove to offer advantages in performance over the individual use of either chemical. | 2010-04-22 |
20100099597 | Amylase Variants - The present invention relates to variants of a parent α-amylase, which parent α-amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, and SEQ ID No. 7, respectively; or (ii) displays at least 80% homology with one or more of these amino acid sequences; and/or displays immunological cross-reactivity with an antibody raised against an α-amylase having one of these amino acid sequences; and/or is encoded by a DNA sequence which hybridizes with the same probe as a DNA sequence encoding an α-amylase having one of these amino acid sequences; in which variant: | 2010-04-22 |
20100099598 | Amylase Variants - The present invention relates to variants of a parent α-amylase, which parent α-amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, and SEQ ID No. 7, respectively; or (ii) displays at least 80% homology with one or more of these amino acid sequences; and/or displays immunological cross-reactivity with an antibody raised against an α-amylase having one of these amino acid sequences; and/or is encoded by a DNA sequence which hybridizes with the same probe as a DNA sequence encoding an α-amylase having one of these amino acid sequences; in which variant: | 2010-04-22 |
20100099599 | ENHANCED PERFORMANCE HYDROGEN PEROXIDE FORMULATIONS COMPRISING PROTEINS AND SURFACTANTS - Disclosed herein are compositions comprising: an oxidizing agent; a surfactant; and a protein component. Also disclosed are methods of cleaning a surface, the method comprising applying an aqueous solution to the surface, the solution comprising the above compositions. | 2010-04-22 |
20100099600 | CANDIDATES AGAINST INFECTION - The present invention relates to the use of plasminogen/plasmin and its derivatives as agents for enhancing host defense against infection or other infectious diseases. The invention also relates to a method for screening of compounds which enhance host defense against infection by evaluating the host defense against bacterial arthritis and spontaneous otitis media in an animal model. | 2010-04-22 |
20100099601 | FIBRILLATION-RESISTANT INSULIN AND INSULIN ANALOGUES - A fibrillation-resistant insulin analogue may be a single-chain insulin analogue or a physiologically acceptable salt thereof, containing an insulin A chain sequence or an analogue thereof and an insulin B chain sequence or an analogue thereof connected by a polypeptide of 4-10 amino acids. The fibrillation-resistant insulin analogue preferably displays less than 1 percent fibrillation with incubation at 37° C. for at least 21 days. A single-chain insulin analogue displays greater in vitro insulin receptor binding than normal insulin while displaying less than or equal binding to IGFR than normal insulin. The fibrillation-resistant insulin may be used to treat a patient using an implantable or external insulin pump, due to its greater fibrillation resistance. | 2010-04-22 |
20100099602 | PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE FOR THE PREVENTION AND TREATMENT OF HYPOXIC INJURY - The invention is directed to compositions and methods for using the same for the prevention and treatment of hypoxic conditions, ischemia/reperfusion injury and the sequels thereof. | 2010-04-22 |
20100099603 | LYOPHILIZED RECOMBINANT VWF FORMULATIONS - The present invention provides long-term stable pharmaceutical formulations of lyophilized recombinant von-Willebrand Factor (rVWF) and methods for making and administering said formulations. | 2010-04-22 |
20100099604 | PEPTIDIC AND NON PEPTIDIC LIGANDS FOR IMMUNODETECTION OF THE RECEPTOR FOR UROTENSIN - The use of opportunely modified specific ligands of the receptor for urotensin II (UTR) or antibodies (commercially available) raised against the same receptor as tools for the definition of both the differentiation and the prognosis of human prostate adenocarcinoma is described, moreover, the use of opportunely radiolabeled ligands for UTR in the definition of the extension of disease is also described. | 2010-04-22 |
20100099605 | CHAPERONIN 10 IMMUNOSUPPRESSION - The invention is directed to the use of cpn10 in transplantation and particularly to treatment and/or prevention of graft versus host disease. The invention provides a method of administration of cpn10 to a donor and/or recipient animal or cells, tissues or organs derived from the donor, although in a particularly advantageous form treatment of both the donor and recipient animal. The method may further include the administration to the donor and/or recipient animal at least one other immunosuppressive agent to prevent or alleviate graft versus host disease. | 2010-04-22 |
20100099606 | EFFECTIVE USE METHOD OF MEDICAMENTS AND METHOD OF PREVENTING EXPRESSION OF SIDE EFFECT - To provide a medicament which efficiently expresses an immunosuppressive agent or an anti-inflammatory agent and reduces expression of side effect. | 2010-04-22 |
20100099607 | CASEIN COMPLEXES - Complexes comprising resveratrol and a casein, a process for their manufacture, their uses and compositions comprising them. | 2010-04-22 |
20100099608 | TREATMENT OF DEMYELINATING DISORDERS WITH SOLUBLE LYMPHOTOXIN-BETA-RECEPTOR - Methods of treating a demyelinating disorder using inhibitors of the lymphotoxin pathway. | 2010-04-22 |
20100099609 | eAPP AND DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE - This invention provides methods of reducing levels of amyloid beta (Aβ) protein and/or netrin-1 in a mammal. In certain embodiments the methods involve administering to the mammal a fragment of an amyloid precursor protein, or a mutant amyloid precursor protein, in an amount sufficient to decrease circulating levels of free Aβ protein in said mammal, wherein said fragment is a fragment of the extracellular domain of APP or a mutant thereof that binds amyloid beta protein and/or netrin-1. | 2010-04-22 |
20100099610 | Transglutaminase Variants with Improved Specificity - Variants of transglutaminase from | 2010-04-22 |
20100099611 | ANTI-ANGIOGENIC PEPTIDES - A purified polypeptide includes about 10 to about 40 amino acids and has an amino acid sequence corresponding to a portion of SEQ ID NO: 2. The polypeptide can inhibit binding of VEGF to VEGFR2 of cells that express VEGFR2. | 2010-04-22 |
20100099612 | RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS - This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer. | 2010-04-22 |
20100099613 | PEPTIDES FOR INDUCING A CTL AND/OR HTL RESPONSE TO HEPATITIS C VIRUS - The present invention is directed to peptides, and nucleic acids encoding them, derived from the Hepatitis C Virus (HCV). The peptides are those which elicit a CTL and/or HTL response in a host. The invention is also directed to compositions and vaccines for prevention and treatment of HCV infection and diagnostic methods for detection of HCV exposure in patients. | 2010-04-22 |
20100099614 | Antimicrobial Peptides and Methods of Use - Disclosed herein are antimicrobial peptides with useful and/or superior properties such as specificity, resistance to degradation, antimicrobial activity, desirably low levels of hemolytic activity, and a therapeutic index against a broad range of microorganisms including gram-negative, gram-positive and acid-fast bacteria, fungi and other organisms. Also provided are pharmaceutical compositions comprising these peptides and methods of using such peptides to control microbial growth or to treat or reduce incidence of infections caused by such microorganisms. Also disclosed are peptides at least one or all amino acids in the D configuration. Compositions disclosed herein are useful in the treatment of bacterial, mycobacterial and/or fungal infections or for reducing microbial cell numbers or growth on surfaces or in materials. | 2010-04-22 |
20100099615 | PANCREATIC REGENERATING PROTEIN I IN CHRONIC PANCREATITIS AND AGING IMPLICATIONS FOR NEW THERAPEUTIC APPROACHES TO DIABETES - The present invention provides a method of treating diabetes, including administering to a mammal diagnosed with diabetes a purified recombinant reg I protein. | 2010-04-22 |
20100099616 | MODIFIED BLOOD FACTORS COMPRISING A LOW DEGREE OF WATER SOLUBLE POLYMER - The present invention relates, in general, to materials and methods for the preparation of modified blood factors which have low levels of water soluble polymer molecules conjugated to the blood factor but exhibit biological activity similar to or better than molecules having a higher number of water soluble polymer moieties. | 2010-04-22 |
20100099617 | Secreted proteins - The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP. | 2010-04-22 |
20100099618 | Interleukin-9 and Interleukin-4 Chimeric Antagonist Muteins and Methods of Using Same - Chimeric polypeptide antagonists that include an interleukin-4 (IL-4) mutein linked to an interleukin-9 (IL-9) mutein are provided, as are polynucleotides encoding the IL-4 and IL-9 chimeric mutein antagonists. Also provided are methods of using the chimeric mutein antagonists and encoding polypeptides to reduce or inhibit the responsiveness of a cell to a cytokine such as IL-4, IL-9 and/or interleukin-13. Methods using the compositions to treat disorders such as pulmonary disorders (e.g., asthma) also are provided. | 2010-04-22 |
20100099619 | PANCREATIC POLYPEPTIDE FAMILY MOTIFS, POLYPEPTIDES AND METHODS COMPRISING THE SAME - The present invention provides novel Pancreatic Polypeptide Family (“PPF”) polypeptides and methods for their use. | 2010-04-22 |
20100099620 | Protracted GLP-1 Compositions - Thixotropic compositions containing GLP-1 compounds have protracted action. | 2010-04-22 |
20100099621 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula | 2010-04-22 |
20100099622 | WOUND HEALING - The present invention relates to the use of p38 MAP kinase inhibitors and p38 MAP kinase inhibition to promote wound healing. | 2010-04-22 |
20100099623 | Cross-Linked Collagen and Uses Thereof - The present invention discloses collagen cross-linked in a micro to non-fibrillar form and at a high concentration. The cross-linked collagen gel has improved volume stability or persistence than collagen cross-linked at a neutral pH. Also disclosed are methods for preparing the inventive cross-linked collagen and using such for augmenting soft tissues in mammals. | 2010-04-22 |
20100099624 | CROSS-LINKED COLLAGEN AND USES THEREOF - The present invention discloses collagen cross-linked in a micro to non-fibrillar form and at a high concentration. The cross-linked collagen gel has improved volume stability or persistence than collagen cross-linked at a neutral pH. Also disclosed are methods for preparing the inventive cross-linked collagen and using such for augmenting soft tissues in mammals. | 2010-04-22 |
20100099625 | Bio-security system - A method for preventing contamination of a teat during administration of a sealant comprises the steps of introducing/delivering a sterilising agent into the teat and subsequently delivering the sealant into the teat. A sealant injector | 2010-04-22 |
20100099626 | CELL PENETRATING PEPTIDES FOR INTRACELLULAR DELIVERY OF MOLECULES - The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX | 2010-04-22 |
20100099627 | NUCLEAR TARGETING SEQUENCES - Isolated peptides comprising nuclear targeting activity or being capable of preventing endogenous nuclear targeting activity are disclosed. Polynucleotides encoding same, pharmaceutical compositions comprising same, as well as uses thereof are also disclosed. | 2010-04-22 |
20100099628 | CARBOHYDRATE-BASED PERITONEAL DIALYSIS FLUID COMPRISING GLUTAMINE RESIDUE - The present invention relates to a carbohydrate-based peritoneal dialysis fluid, containing a compound selected from the group consisting of glutamine, preferably L-glutamine, a dipeptide capable of releasing glutamine, L-glutamine in free form, preferably selected from the group consisting of glutaminyl-glycine, glycinyl-glutamine, glutaminyl-alanine, alanyl-glutamine an oligopeptide consisting of two to seven glutamine, preferably L-glutamine residues, and mixtures thereof. The peritoneal dialysis fluids of the present invention are useful for inhibition of technical failure in a person undergoing peritoneal dialysis treatment. | 2010-04-22 |
20100099629 | OPHTHALMOLOGICAL COMPOSITION - An object is to find the minimum activity expression site of fibronectin, clarify the actions of this minimum unit in relation to opthalmological fields, and provide an opthalmological composition having this minimum unit as an effective component. This invention provides an opthalmological composition, in particular, a corneal disorder treatment agent containing the peptide, PHSRN (SEQ ID NO: 1) (Pro-His-Ser-Arg-Asn (SEQ ID NO: 1)), or Ac-Pro-His-Ser-Arg-Asn-NH | 2010-04-22 |
20100099630 | Method for improving ventilatory efficiency - This invention is a method of improving the function of the pulmonary arm of the cardiac-pulmonary axis by the administration of a pharmaceutical or nutritional supplement to a patient in which the function of the pulmonary arm is suboptimal, but not as a sequella of dysfunction of the cardiac arm. The exemplar patient is one suffering from chronic obstructive pulmonary disease. The preferred pentose is D-ribose, to be administered chronically. | 2010-04-22 |
20100099631 | Novel Use - The present invention relates to the use of the combined oral administration of caffeine with carbohydrate for increasing the rate of muscle glycogen resynthesis after strenuous exercise. | 2010-04-22 |
20100099632 | Oligosaccharide Aldonic Acids and Their Topical Use - Methods for using compositions comprising oligosaccharide aldonic acids for general care, as well as for treatment and prevention, of various cosmetic conditions and dermatological disorders, including those associated with intrinsic and/or extrinsic aging, as well as with changes or damage caused by extrinsic factors; general care, as well as treatment and prevention of diseases and conditions, of the oral, and vaginal mucosa; for general oral care, as well as treatment and prevention of oral and gum diseases; and for wound healing of the skin. Methods may comprise using compositions comprising oligosaccharide aldonic acids and additional cosmetic, pharmaceutical or other topical agents to enhance or create synergetic effects. | 2010-04-22 |
20100099633 | METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES - The present application relates to a method for enhancing absorption of a nutrient in a subject in need thereof with an effective amount of an isolated astragaloside compound. | 2010-04-22 |
20100099634 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY - The present invention relates to macrolide derivatives of formula (I) in which R | 2010-04-22 |
20100099635 | METHOD FOR TREATING CYSTIC FIBROSIS - The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, and administering to the patient an effective amount of denufosol or a pharmaceutically acceptable salt thereof and an effective amount of a macrolide. In one method, denufosol and the macrolide are administered by inhalation, preferably in a single formulation. In another method, denufosol is administered by inhalation and the macrolide is administered orally. The present invention is also directed to a pharmaceutical formulation comprising denufosol or a pharmaceutically acceptable salt thereof, a macrolide, and a pharmaceutically acceptable carrier. Preferred denufosol is denufosol tetrasodium and preferred macrolide is azithromycin. The pharmaceutical formulation preferably is in a form of an inhalable dry powder or in a liquid form. | 2010-04-22 |
20100099636 | HYDROUS GEL AND PRODUCTION PROCESS AND USE OF THE HYDROUS GEL - A hydrous gel substantially comprising at least two polymers selected from the group consisting of polyacrylic acid, sodium polyacrylate and partially neutralized polyacrylate, and water, the polymers being crosslinked by containing an aluminum compound, wherein the pH when the hydrous gel is 100-fold diluted with purified water is from 6.5 to 8.5. A hydrous gel which can stably hold an ascorbic acid or a derivative thereof, has high gel strength, exhibits good adhesion to an adherend and causes no liquid syneresis can be provided. | 2010-04-22 |
20100099637 | USE OF CYCLOARTANE COMPOUNDS FOR TREATING ARTHRITIS - A method of treating a disease associated with cartilage defect in a subject in need thereof by administering to the subject an effectively amount of a cycloartane compound of Formula (I). | 2010-04-22 |
20100099638 | IMMUNOCOMPETENT XENOGRAFT MODEL - The teachings are directed to an immunocompetent xenograft model. The model comprises an immunodeficient animal modified to have a reconstituted immune system, wherein a xenograft is transplanted in the animal and allowed to establish for an establishment period of at least about 10 days. The xenograft simulates a tissue in a subject in need of a treatment. In these embodiments, the reconstituted immune system is created after the establishment period, and is created by administering a total number of T-cells to the animal. The total number of T-cells consists of a preselected number of responsive T-cells, a preselected number of non-responsive T-cells, and a preselected ratio of responsive T-cells to total T-cells. The preselected number of responsive T-cells simulates a number of responsive T-cells in the subject, and the ratio of the number of responsive T-cells to total T-cells ranges from about 1:100,000 to about 30:100,000. | 2010-04-22 |
20100099639 | W/O/W EMULSION COMPOSITION - The present invention provides a W/O/W multiple emulsion composition composed of an internal aqueous phase, an oil phase, and an external aqueous phase, the internal aqueous phase containing an ionic physiologically active substance and a physiologically acceptable compound having a molecular weight of 1,000 or less and generating a polyvalent counterion with two or more valencies for the ionic physiologically active substance. The W/O/W emulsion composition of the present invention not only can stably encapsulate a useful substance in its internal aqueous phase at a high encapsulation ratio, but also has high safety. | 2010-04-22 |
20100099640 | TISSUE DEGENERATION PROTECTION - The present invention provides isolated or essentially pure diterpenoic tetrahydropyran, such as steviol-19-glucuronide, steviol, stevioside and rebaudioside processes for obtaining the same and methods for obtaining stable pharmaceutically acceptable salts of the same for use of such compounds or compositions in a treatment of cardiovascular disorders or vascular disease or for the manufacture of medicaments to treat a condition of a cardiovascular disorder or vascular disease. | 2010-04-22 |
20100099641 | CRYSTALLINE FORM OF 1-CHOLORO-4-(BETA-D-GLUCOPYRANOS-1-YL)-2-[4-((S)-TETRAHYDROFURAN-3-YLOXY)- -BENZYL]-BENZENE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS - The invention relates to a crystalline form of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments. | 2010-04-22 |
20100099642 | TGF-BETA STIMULANT AND FURTHER AGENT TO REDUCE SIDE EFFECTS - The invention relates to the use of TGF-beta stimulating agents, and in particular members of the triphenylethylene class of pharmaceutical agents, for the prevention, prophylaxis, treatment or amelioration of symptoms of cardiovascular disease, autoimmune diseases or neurodegeneration. In particular, improved compositions consisting of triphenylethylene agents combined with one or more additional active pharmaceutical agents in order to mitigate against side-effects of the triphenylethylene are described and claimed. | 2010-04-22 |
20100099643 | Fused Pentacyclic Polyethers - Disclosed are polycyclic polyether compounds of formula I and pharmaceutical compositions comprising such compounds. | 2010-04-22 |
20100099644 | HPMA - DOCETAXEL OR GEMCITABINE CONJUGATES AND USES THEREFORE - Disclosed are water-soluble compositions of gemcitabine and docetaxel formed by conjugating the gemcitabine or docetaxel to a water-soluble polymer such as N-2-hydroxypropyl methacrylamide (HPMA). Also disclosed are methods of using the compositions of the invention for the treatment of cancer. | 2010-04-22 |
20100099645 | Compositions containing pufa and methods of use thereof - This invention provides methods of increasing or enhancing the synthesis and levels of phospholipids, synapses, synaptic proteins, and synaptic membranes by a neural cell or brain cell; methods of treating a subject with a memory disorder, memory impairment, neurological disorder, or brain disease or disorder, comprising administering to the subject a composition comprising an omega-3 fatty acid, an omega-6 fatty acid, uridine, a metabolic precursor thereof, or a combination thereof. | 2010-04-22 |
20100099646 | W/O/W EMULSION COMPOSITION - A W/O/W emulsion composition having high emulsion stability, which can be prepared extremely easily and for which the production efficiency of the W/O/W emulsion product is favorable, and a method of producing such a W/O/W emulsion composition. The W/O/W emulsion composition of the present invention includes 0.001 to 60% by mass of a component (A) described below and 0.001 to 10% by mass of a component (B) described below; wherein, a mass ratio between the component (A) and the component (B) is within a range from 1:0.01 to 1:1.4. Component (A): a sugar fatty acid ester composition obtained by esterifying a sugar and a fatty acid of 8 to 28 carbon atoms, in which a hydroxyl value of said sugar fatty acid ester composition is within a range from 20 to 220. Component (B): a nonionic surfactant having an HLB value of not less than 7. | 2010-04-22 |
20100099647 | Aqueous Iron Carbohydrate Complexes, Their Production And Medicaments Containing Them - Water soluble iron carbohydrate complex obtainable from an aqueous solution of iron(III) salt and an aqueous solution of the oxidation product of one or more maltodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, process for its production and medicament for the treatment and prophylaxis of iron deficiency conditions. | 2010-04-22 |
20100099648 | NATURAL EQUIVALENT OF CHEMICALLY MODIFIED STARCH - The present invention relates to a composition comprising citrus fruit fiber having a water binding capacity of from 8 to 25 (w/w) and native starch selected from the group consisting of corn starch, rice flour, sorghum starch, tapioca starch and mixture thereof. | 2010-04-22 |
20100099649 | SITE-SPECIFIC CHEMICAL MODIFICATION OF PROTEINS AT THEIR N-TERMINI, ENABLING THE FORMATION OF HOMOGENEOUS ADDUCTS - Site-specific modifications of proteins at their N-termini are provided. In particular, a chemical modification of proteins at their N-termini via a transamination reaction to form homogeneous adducts such as, the corresponding oxime derivatives is provided. Methods of making and using the adducts in radio-labelling, molecular imaging applications, and treatment of disorders such as cancer, Crohn's disease, arthritis, atherothrombosis and plaque rupture are also provided. | 2010-04-22 |
20100099650 | NASAL SPRAY COMPOSITION AND METHOD FOR TREATING RHINITIS, SINUSITIS OR BOTH - A nasal spray composition for treating mucosal inflammation associated with rhinitis, sinusitis, or both can include a decongestant and at least one therapeutic agent. The therapeutic agent is selected from the group consisting of an anti-inflammatory agent and an anti-histamine agent. The nasal spray composition is non-habituating and is administered intranasally to a subject in need thereof. | 2010-04-22 |
20100099651 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF RESPIRATORY AND GASTROINTESTINAL DISORDERS - The present invention relates to novel pharmaceutical compositions comprising at least one EGFR kinase inhibitor and at least one additional active compound selected from beta-2 mimetics, steroids, PDE-IV inhibitors, p38 MAP kinase inhibitors, NK | 2010-04-22 |
20100099652 | NOVEL COMPOSITION BASED ON CHOLEST-4-EN-3-ONE OXIME - A subject of the invention is a novel composition, particularly a pharmaceutical composition comprising cholest-4-en-3-one oxime and an oil chosen from sesame oil, olive oil, soya oil, cotton oil, or a mixture of commercial medium-chain triglycerides (ESTASAN®, MYGLIOL®), or a mixture of these oils, preferably sesame oil, olive oil or soya oil, even more preferably sesame oil. | 2010-04-22 |
20100099653 | Particle Size Reduction Apparatus, and Use Thereof - A sterilisable particle-size reduction apparatus, component parts thereof and a method of sterilising and validating sterility thereof are provided. Also provided is use thereof to prepare sterile suspensions of drugs. | 2010-04-22 |
20100099654 | FATTY ACID ESTERS OF GLUCOCORTICOIDS AS ANTI-INFLAMMATORY AND ANTI-CANCER AGENTS - The present invention relates to certain unsaturated fatty acid derivatives of therapeutically active glucocorticoides-fatty acid esters of glucocorticoids as anti-inflammatory and anti-cancer agents and pharmaceutical formulations containing them. | 2010-04-22 |
20100099655 | IMPLANTS AND METHODS FOR TREATING INFLAMMATION-MEDIATED CONDITIONS OF THE EYE - Methods for treating inflammation-mediated conditions of the eye are described, comprising: implanting into the vitreous of the eye of an individual a bioerodible implant comprising a steroidal anti-inflammatory agent and a bioerodible polymer, wherein the implant delivers the agent to the vitreous in an amount sufficient to reach a concentration equivalent to at least about 0.05 μg/ml dexamethasone within about 48 hours and maintains a concentration equivalent to at least about 0.03 μg/ml dexamethasone for at least about three weeks. | 2010-04-22 |
20100099656 | Neurotherapeutic compositions - Novel neuroprotectant compositions and methods are described. (β-Lactamase inhibitors are used to prevent or reduce loss of neuronal cells and neuronal cell function in patients afflicted with or susceptible to disease states or conditions known to result in or cause neuronal tissue insult. | 2010-04-22 |