17th week of 2014 patent applcation highlights part 50 |
Patent application number | Title | Published |
20140114188 | ACOUSTO-OPTIC VIBROMETER - An acousto-optic vibrometer includes: an acoustic wave source to irradiating an object with an acoustic wave; an acoustic lens system which places a scattered wave from the object into a predetermined converged state; an acousto-optic medium portion in which the scattered wave transmits; a sensing light source to emit a sensing light beam in which monochromatic rays of light with different traveling directions are superposed and which is incident on the acousto-optic medium portion; a reference light source to emit a reference light beam in which monochromatic rays of light with different traveling directions are superposed and which is to be superposed on sensing light beam based diffracted light produced by the acousto-optic medium portion; an imaging lens system which converges the diffracted light on which the reference light beam is superposed; and an image receiving section which senses the light converged by the imaging lens system. | 2014-04-24 |
20140114189 | ULTRASOUND DIAGNOSTIC APPARATUS AND METHOD - According to an embodiment, an analyzer analyzes the state of a tissue at a position in a subject from which an ultrasound wave that is transmitted by an ultrasound probe into the subject is reflected, the analysis being on the basis of a received signal of the ultrasound wave. A signal acquiring unit acquires noises signal information corresponding to an area that is analyzed by the analyzer. A noise area extracting unit determines, regarding each area analyzed by the analyzer, whether the received signal that is used for the analysis performed by the analyzer is a noise signal, the determination being on the basis of the noise signal information acquired by the signal acquiring unit. A display controller configured controls a display unit such that the display unit displays an area regarding which the area extracting unit determines that the received signal is a noise signal. | 2014-04-24 |
20140114190 | TABLET ULTRASOUND SYSTEM - Exemplary embodiments provide systems and methods for portable medical ultrasound imaging. Certain embodiments provide a multi-chip module for an ultrasound engine of a portable medical ultrasound imaging system, in which a transmit/receive chip, an amplifier chip and a beamformer chip are assembled in a vertically stacked configuration. Exemplary embodiments also provide an ultrasound engine circuit board including one or more multi-chip modules, and a portable medical ultrasound imaging system including an ultrasound engine circuit board with one or more multi-chip modules. Exemplary embodiments also provide methods for fabricating and assembling multi-chip modules as taught herein. A single circuit board of an ultrasound engine with one or more multi-chip modules may include 16 to 128 channels in some embodiments. Due to the vertical stacking arrangement of the multi-chip modules, a 128-channel ultrasound engine circuit board can be assembled within exemplary planar dimensions of about 10 cm×about 10 cm. | 2014-04-24 |
20140114191 | STRUCTURED RANDOM PERMUTATION PULSE COMPRESSION SYSTEMS AND METHODS - A structured randomly permutated pulse compression system comprises an FM transmitter configured to receive an input signal and transmit an output signal. The FM transmitter is configured to modulate the frequency of the output signal by modulating the frequency of the output signal according to a structured random permutation of time samples of the input signal. At least one antenna interfaces with the FM transmitter. The FM receiver is configured to auto-correlate the output signal with a return signal. | 2014-04-24 |
20140114192 | Non-Contact Measuring Method and Apparatus in Pediatrics - A non-contact measuring method in pediatrics is disclosed. An infant model is established by acquiring a human image and a depth image of a subject infant; updating the infant model by acquiring a plurality of anthropometric characteristic points and finally obtaining an anthropometric data of the subject infant from the updated infant model. This invention also provides an apparatus to achieve the above mentioned measuring method. An infant model which includes anthropometric characteristic points and 3D surface models is established based on a human image acquired by an image acquisition module and a depth image acquired by a depth information acquisition module in conjunction with an algorithm program built in a data acquisition and processing module. Human anthropometric data is obtained by analyzing the infant model. The non-contact measuring method and measuring apparatus in pediatrics make the measuring process more humane without contacting a subject body. | 2014-04-24 |
20140114193 | ULTRASOUND SCANNING SYSTEM - A force-controlled ultrasound imaging device uses a linear drive system to maintain a suitable contact force with a subject. A combination of hardware and software limits on travel for the linear drive system provide intuitive user feedback while helping to ensure that the linear drive system remains active throughout the scan, while responding appropriately to initiation and termination of scans. | 2014-04-24 |
20140114194 | ULTRASOUND DIAGNOSIS APPARATUS AND ULTRASOUND PROBE CONTROLLING METHOD - An ultrasound diagnosis apparatus according to an embodiment includes a detecting unit and a deflecting unit. The detecting unit detects at least one selected from between a force applied to an ultrasound probe and a movement of the ultrasound probe. The deflecting unit tilts a transmission direction of an ultrasound wave transmitted from the ultrasound probe, based on at least one selected from between the force and the movement. | 2014-04-24 |
20140114195 | ULTRASOUND UNIT AND ULTRASOUND ENDOSCOPE - An ultrasound unit includes an ultrasound array that has a plurality of ultrasound elements, each of which has a first principal surface that is rectangular where a transmitting and receiving portion, a signal electrode terminal, and a ground electrode terminal are arranged in a longer side direction, longer sides of the ultrasound elements being coupled, one or more short-lines that are connected to a plurality of ground electrode terminals, a ground line that is connected to the short-line, and a plurality of signal lines, each of which is connected to one of the signal electrode terminals, and adjoining ultrasound elements of the ultrasound elements are coupled such that the signal electrode terminals are arranged alternately on opposite sides in the longer side direction of the transmitting and receiving portions that are rectangular. | 2014-04-24 |
20140114196 | MEASUREMENT PROBE, BIO-OPTICAL MEASUREMENT APPARATUS AND BIO-OPTICAL MEASUREMENT SYSTEM - A measurement probe has a fiber bundle formed by irregularly bundling a plurality of optical fibers, is detachably connected to a bio-optical measurement apparatus performing optical measurement to a biological tissue that is an object to be measured, and includes a recording unit | 2014-04-24 |
20140114197 | Probe - A probe is shown. According to one implementation, the following is included at a tip of the probe, as the optical system. A first optical fiber system forms an irradiating light guiding path to guide irradiating light. A second optical fiber system forms a receiving light guiding path to guide measuring light. A condenser lens system is positioned opposed to the first optical fiber system and the second optical fiber system, and the irradiating light is irradiated thereon and the measuring light is condensed. An optical axis of the condenser lens system, a central axis of a light emitting end of the first optical fiber system, and a central axis of a light receiving end of the second optical fiber system are positioned so a straight line which passes through two axes does not pass through a remaining axis. | 2014-04-24 |
20140114198 | Optical Connector Plug, Optical Probe, And Optical System - Provided is an optical connector plug of which housing is provided with: a first member that has at least a lower surface section that covers the lower side of a providing space in which an optical fiber and a ferrule are provided, a half of a back surface section from which the optical fiber is led out, and a half of a front surface section from which the ferrule is led out, and is composite-molded out of a thermoplastic resin; and a second member that has at least an upper surface section that covers the upper side of the providing space, the remaining half of the back surface section and the remaining half of the front surface section, and is composite-molded out of a thermoplastic resin into the same shape as the first member. | 2014-04-24 |
20140114199 | MAGNETIC-FLAP OPTICAL SENSOR - A magnetic-flap optical sensor has an emitter activated so as to transmit light into a fingertip inserted between an emitter pad and a detector pad. The sensor has a detector responsive to the transmitted light after attenuation by pulsatile blood flow within fingertip so as to generate a detector signal. Flaps extend from the emitter pad and along the sides of a detector shell housing the detector pad. Flap magnets are disposed on the flap ends and shell magnets are disposed on the detector shell sides. A spring urges the emitter shell and detector shell together, so as to squeeze the fingertip between its fingernail and its finger pad. The flap magnets have opposite north and south orientations from the shell magnets, urging the flaps to the detector shell sides and squeezing the fingertip sides. These spring and magnet squeezing forces occlude the fingertip blood flow and accentuate a detector signal responsive to an active pulsing of the fingertip. | 2014-04-24 |
20140114200 | COMPOSITE MANUAL AND AUTOMATED FETAL ANALYSIS SYSTEMS AND METHODS - A composite manual and automated fetal strip analysis system is disclosed. A computer is configured to receive at least one of a signal indicative of said physiological parameter of a fetus and a signal indicative of uterine activity and automatically detect a pre-determined pattern. A user interface allows a user to manually alter results of the automatic detection. | 2014-04-24 |
20140114201 | PORTABLE INFORMATION TERMINAL - A mobile information terminal includes: a directional microphone provided with a front port, a diaphragm and an electrode, wherein the microphone includes a front air chamber formed between a flexible thin film which covers an opening of the front port and the diaphragm, and a rear air chamber formed between a case and the electrode by hermetically covering a rear of the electrode with the case. | 2014-04-24 |
20140114202 | BLOOD WITHDRAWAL CANNULA OF A PUMP REPLACING OR ASSISTING ACTIVITY OF THE HEART - The invention relates to a blood withdrawal cannula ( | 2014-04-24 |
20140114203 | SYSTEMS AND METHODS FOR OFF-LINE REPROGRAMMING OF IMPLANTABLE MEDICAL DEVICE COMPONENTS TO REDUCE FALSE DETECTIONS OF CARDIAC EVENTS - Techniques are provided for use by implantable medical devices such as pacemakers or by external systems in communication with such devices. An intracardiac electrogram (IEGM) is sensed within a patient in which the device is implanted using a cardiac signal sensing system. Cardiac events of interest such as arrhythmias, premature atrial contractions (PACs), premature ventricular contractions (PVCs) and pacemaker mediated tachycardias (PMTs) are detected within the patient using event detection systems and then portions of the IEGM representative of the events of interest are recorded in device memory. Subsequently, during an off-line or background analysis, the recorded IEGM data is retrieved and analyzed to identify false detections. In response to false detections, the cardiac signal sensing systems and/or the event detection systems of the implantable device are selectively adjusted or reprogrammed to reduce or eliminate any further false detections, including false-positives or false-negatives. Various adaptive reprogramming techniques are described. | 2014-04-24 |
20140114204 | METHOD AND SYSTEM FOR DETECTION OF BIOLOGICAL RHYTHM DISORDERS - System, assembly and method are provided to facilitate reconstruction of cardiac information representing a complex rhythm disorder associated with a patient's heart to indicate a source of the heart rhythm disorder. The complex rhythm disorder can be treated by application of energy to modify the source of the rhythm disorder. | 2014-04-24 |
20140114205 | GENERAL-PURPOSE MEDICAL INSTRUMENTATION - A general-purpose, low-cost system provides comprehensive physiological data collection, with extensive data object oriented programmability and configurability for a variety of medical as well as other analog data collection applications. A general-purpose data routing and encapsulation architecture supports input tagging and standardized routing through modern packet switch networks, including the Internet; from one of multiple points of origin or patients, to one or multiple points of data analysis for physician review. The preferred architecture further supports multiple-site data buffering for redundancy and reliability, and real-time data collection, routing, and viewing (or slower than real-time processes when communications infrastructure is slower than the data collection rate). Routing and viewing stations allow for the insertion of automated analysis routines to aid in data encoding, analysis, viewing, and diagnosis. | 2014-04-24 |
20140114206 | Methods For Detecting Bacterial Infections - The invention is directed to methods of detecting lung, gastrointestinal tract, and systemic infections by measuring | 2014-04-24 |
20140114207 | Cognitive Management Method and System - A cognitive management method and system that monitors and manipulates a response signal from a neurological organ to optimize cognitive performance and behavioral management of the neurological organ. The method allows a user to transmit a stimulus signal such as optical or auditory to the organ and receive a return signal in response. A sensor, such as EEG electrodes detects the response signal. The response signal generated by the neurological organ is then detected by the sensor and transmitted to data storage. The signal can be reconfigured and retransmitted to a display device. The signal includes Hertz and real time frequencies. The signal includes a signal parameter with a high range and a low range. An alert actuates when the signal exceeds the parameter. The signal is monitored by the user and invited followers to analyze and treat cognitive performance and behavior. | 2014-04-24 |
20140114208 | METHOD OF TREATING VISION DISORDERS - This invention is in the field of the treatment of eye disorders. In particular, it relates to the use of a remote monitoring system for determining patient response to therapeutic treatment, in particular with VEGF antagonists. | 2014-04-24 |
20140114209 | Method and Apparatus for measuring Distortion Product Otoacoustic Emissions (DPOAE) by means of frequency modulated stimuli - A method to reduce DPOAE fine structure in the measurement of DPOAE acoustic signals generated in the cochlea in response to two primary tones. | 2014-04-24 |
20140114210 | BIOPSY DEVICE WITH AUTOMATIC ASPIRATION - The invention provides a disposable endometrial biopsy device comprising an elongated blunt-end catheter with distally placed tissue acquisition side-hole and proximally attached aspiration syringe with spring-loaded plunger having latching mechanism to release plunger for induction of aspiration. The device has a pin-hole channel or filter acting as a tissue trap between the catheter channel and the syringe in order to prevent aspiration of tissue into the body of the syringe. | 2014-04-24 |
20140114211 | DERMALLY AFFIXED DEVICE FOR INTRAVENOUS ACCESS - An improved, injection or blood removal device for intravenous access has a port with a septum at the exterior end of an intravenous catheter, a coupling element having an adhesive surface for securing attachment onto the skin, an injection or blood sampling unit, a connecting cannula piercing the septum of the port, and means to secure functional assembly. Attachment of the device to the skin covering or close to the intravenous puncture site and without long communicating tubes allows ambulant injection of drugs or measuring of concentration-time profiles of exogenous and endogenous analytes to improve treatment modalities on an individualized basis. | 2014-04-24 |
20140114212 | APPARATUS AND METHOD FOR THE ASSESSMENT OF NEURODEVELOPMENTAL DISORDERS - The present invention concerns apparatus for the detection and/or assessment of neurodevelopmental disorders of a user, the apparatus comprising: control means for providing a goal-orientated task to a display, said task being formulated to elicit a movement from a user in response to said task; input means via which a user can input a response to said task; wherein said control means records a user's response as multi-dimensional input data, which can be used to profile the user for the presence or absence of a neurodevelopmental disorder, the task being specifically formulated such that indicative characteristics of a user's movement over time can be identified by said multi-dimensional input data. | 2014-04-24 |
20140114213 | POSTURAL SWAY AND STABILITY MEASUREMENT AND THERAPEUTIC DEVICE AND RELATED METHODS - A postural and sway stability measurement device includes a slidable support that is configured to be mounted on a base such that the slidable support is movable between an initial position and a plurality of a maximum sway positions; and a patient sway unit mounted to the slidable support. The patient sway unit is configured to interact with a patient such that when the patient leans in a direction, the patient sway unit moves the slidable support from the initial position to one of the maximum sway positions to thereby measure an amount of maximum sway for the patient. | 2014-04-24 |
20140114214 | GAIT ASYMMETRY MEASUREMENT - A system for measuring variation in the gait of a subject comprises a sensor arranged to measure variations in vertical position of the subject while the subject takes a series of steps, a processor, and a display. The processor is arranged to identify a plurality of points in a first one of the steps and a plurality of points in a second one of the steps, to identify a plurality of pairs of the points, each pair comprising one point in each of the steps, to determine a value of height for each of the points in each of the pairs, and to control the display to produce a display plotting the heights of the two points in each pair against each other. | 2014-04-24 |
20140114215 | Methods for Renal Neuromodulation and Associated Systems and Devices - Methods for treating preventing or decreasing the likelihood of a human patient developing hypertension and associated systems and methods are disclosed herein. One aspect of the present technology, for example, is directed to methods for therapeutic renal neuromodulation that partially inhibit sympathetic neural activity in renal nerves proximate a renal blood vessel of a human patient. This reduction in sympathetic neural activity is expected to therapeutically treat one or more conditions associated with hypertension or prehypertension of the patient. Renal sympathetic nerve activity can be modulated, for example, using an intravascularly positioned catheter carrying a neuromodulation assembly, e.g., a neuromodulation assembly configured to use electrically-induced, thermally-induced, and/or chemically-induced approaches to modulate the renal nerves. | 2014-04-24 |
20140114216 | SYSTEMS AND METHODS FOR OPENING OF A TISSUE BARRIER IN PRIMATES - Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions. | 2014-04-24 |
20140114217 | SYSTEMS AND METHODS FOR PROMOTING LOCOMOTION AND FACILITATING EXERCISE - In one embodiment, a therapy apparatus includes a support, a body harness mounted to the body support, a gearbox positioned below the harness, the gearbox comprising at least one gear and supporting a crankshaft, crankarms mounted to the crankshaft, and pedals mounted to the crankarms, a driveshaft coupled to the at least one gear such that rotation of the driveshaft results in rotation of the crankshaft, crankarms, and pedals, and a motor that drives the driveshaft, wherein the apparatus is adapted to support part of the weight of an subject with the harness and part of the weight of the subject with the pedals and wherein rotation of the pedals due to operation of the motor provides therapy to the subject. | 2014-04-24 |
20140114218 | Method of providing a leg crutch - The method of providing leg support for an ambulatory patient comprising
| 2014-04-24 |
20140114219 | THERAPEUTIC SKIN LIFTING DEVICE AND RELATED SYSTEMS AND METHODS - A therapeutic device has a bridge portion adapted for releasable adherence to a patch of skin so as to lift the patch of skin above a sensitive underlying treatment site in reducing discomfort or pain associated with tissue compression at the treatment site. The bridge portion is elevated above the treatment site with an exposed adhesive facing the patch of skin to be lifted and/or stretched outwardly. With the application of pressure to elastically deform the device from its original neutral configuration, the bridge portion is brought into contact with the patch of skin, adhering the skin to the adhesive. When the pressure is removed, the device rebounds and generally reassumes its original configuration with the bridge portion lifting the attached patch of skin. | 2014-04-24 |
20140114220 | SKIN-STIMULATION UNIT AND SKIN-MASSAGE APPARATUS HAVING SAME - Provided are a skin-stimulation unit and a skin-massage apparatus having same. The skin-stimulation unit comprises: a striking member for applying an impact to the skin; a cap part into which the striking member is slidably inserted; and a connecting rod having a front end connected to the striking member and a rear end connected to an external source of motive powder, wherein the connecting rod linearly reciprocates the striking member. | 2014-04-24 |
20140114221 | ADJUSTABLE HANDHELD ROLLER MASSAGE APPARATUS WITH FABRIC-COVERED RESILIENT AIR-FILLED SPHERICAL CONTACT ORBS - Handheld roller massage apparatus comprising at least two air-filled elastomeric massage spheres and two handle grips attached to a support rod where the handle grips and massage spheres are fully adjustable along the support rod. Massage spheres have special size, elastic modulus, and perceived inflation pressure to reach deep muscle and ligament tissue along either side of the spine. Massage spheres deform from massage pressure primarily in the tip of the sphere and not at the base due to support from T-washer members on either side of massage spheres, which also helps reach deep muscle and ligament tissue along either side of the spine. | 2014-04-24 |
20140114222 | LEG BRACE - Provided herein are devices and methods for bracing a leg (e.g., knee braces). Leg braces are provided that immobilize or partially immobilize the knee joint or other portions of the leg, while further providing components for relieving stress associated with body weight of the subject. | 2014-04-24 |
20140114223 | ANKLE BRACE - The ankle brace includes a calf body defining lateral and medial frontal sides spaced by a frontal opening, and first and second straps depending from the first and second frontal sides of the calf body, respectively. The first and second straps are arranged to extend juxtaposed across the opening and secure to the second and first frontal sides, respectively. The brace also includes opposed lateral and medial ankle struts pivotally attached to the calf body, and a footplate connected to the ankle struts. The medial ankle strut has greater rigidity than the lateral ankle strut. The calf body medial section has greater rigidity than the calf body lateral section. | 2014-04-24 |
20140114224 | Knit Hemostatic Bandage - A knit hemostatic bandage provided herein can include a continuous rayon fiber and a continuous glass fiber. The knit hemostatic bandage can have a gauge of between 10 and 30 stitches per inch. The knit hemostatic bandage can have a Young's modulus of elasticity of less than 50 MPa. | 2014-04-24 |
20140114225 | Shape and Pressure Adjustable Dressing - A dressing for covering a wound. The dressing including: a first component having a first shape with a first dimension; a second component releasably attached to a first surface of the first component to maintain the first component in a second shape different from the first shape, the second shape having a second dimension longer than the first dimension; and an adhesive disposed on a surface of the first component different from the first surface for attaching the first component to the wound such that the second component can be released from the first component to allow the first component to take the first shape to apply a pressure to portions of the skin surrounding the wound to close the wound. Wherein the first and second dimensions are a length in more than one direction. | 2014-04-24 |
20140114226 | Biocompatible Glaucoma Drainage Device - A biocompatible glaucoma drainage device, comprising a non-porous element, a porous element, an anchoring assembly disposed around the non-porous element, wherein the anchoring assembly comprises a plurality of barbs extending outwardly therefrom. | 2014-04-24 |
20140114227 | LYMPHEDEMA MEDICAL DEVICE - Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a medical device for moving lymphatic fluid. The medical device may include an implantable body having an inlet end region and an outlet end region. The inlet end region may include one or more inlet opening. The outlet end region may include one or more outlet openings. A pump member may be positioned between the inlet end region and the outlet end region. The pump member may be configured to draw lymphatic fluid into the implantable body through the inlet end region and transfer lymphatic fluid out from the implantable body through the outlet end region. | 2014-04-24 |
20140114228 | METHODS AND DEVICES TO CURB APPETITE AND/OR TO REDUCE FOOD INTAKE - The present invention relates to devices and methods of operating the devices that contribute to curbing appetite and/or reducing food intake. In some embodiments, the methods and devices of the present invention include as intestinal/duodenal insert comprising an elongated member with at least one flow reduction element that can cause the stimulation of one or more biological signals of satiety. Some embodiments of the inserted device are anchored at the duodenal site by an anchoring member residing in the stomach, other embodiments of the device are stabilized at a targeted site by appropriate dimensions of length as well as one or more angled portions of the device that correspond to angled portions of the targeted site in the dodenum. Embodiments of the device exert effects by virtue of physical presence, as well as by more active forms of intervention, including release of bioactive materials and electrical stimulation of neurons. | 2014-04-24 |
20140114229 | OCULAR IMPLANTS FOR DELIVERY INTO THE EYE - An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. The implant includes a spine extending along a longitudinal axis of the implant, a plurality of curved supports extending from the spine, each support comprising a first end extending from a first location on a first side of the spine and a second end extending from a second location on a second side of the spine, the second location being proximal to the first location, so that each support forms a portion of a helix, the spine and supports defining a volume having a maximum width perpendicular to the longitudinal axis between 0.005 inches and 0.04 inches, the ocular implant being configured to bend preferentially in a preferential bending plane. | 2014-04-24 |
20140114230 | BARIATRIC DEVICE AND METHOD - A bariatric device and method of causing at least partial satiety in a patient, includes positioning a body in a recipient, the body having a wall defining a lumen, the wall configured to generally conform to the shape and size of at least the abdominal portion of the esophagus and the proximal cardiac portion of the stomach. Force is exerted with the wall on the proximal cardiac portion of the stomach in the absence of food thereby activating receptors located in the proximal cardiac portion of the stomach, thereby influencing a neurohormonal feedback mechanism of the patient to cause at least partial satiety by augmenting fullness caused by food and simulating fullness in the absence of food. | 2014-04-24 |
20140114231 | Formulations and Compositions of Hydrophobic Extracts of Skin Tree - This patent discloses formulations, compositions, and process method and device, of hydrophobic extracts and biomass of Skin Tree, also called | 2014-04-24 |
20140114232 | APPARATUS FOR THE TREATMENT AND/OR PREVENTION OF CORNEAL DISEASES - An apparatus for the treatment and/or prevention of corneal diseases includes an applicator head. The applicator head includes a radiation source capable of exciting a non-toxic chromophore. A control is operable to activate the radiation source to radiate, wherein at least one of the following two conditions is met: the applicator head includes a sensor capable of measuring a signal dependent on a position of the applicator head relative to the cornea; or, the applicator head is configured to be in physical contact with the cornea. The control is operable to activate the radiation source to radiate depending on a signal measured by the sensor or to activate the radiation source when the applicator head touches the cornea, respectively. | 2014-04-24 |
20140114233 | METHODS AND SYSTEMS FOR TOXIN DELIVERY TO THE NASAL CAVITY - Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity. | 2014-04-24 |
20140114234 | Systems and Methods for Enhancing the Delivery of Compounds to Skin Pores using Ultrasonic Waveforms - The invention is a device for transmitting acoustical energy through the surface of the skin of a patient, coupled with the administration of a compound, for example an acne medication, for the purpose of temporarily expanding the patient's pore size and enhancing the delivery of the compound to the patient's pores. The ultrasonic transducer emits a sonic transmission of variable intensity and frequency for the purpose of enhancing the absorption of compounds that have first been deposited onto the surface of the skin and into skin pores that have been expanded by the ultrasound transmission. | 2014-04-24 |
20140114235 | Thermal Ablation System With Dispensable Therapeutic - A cassette for a heated fluid ablation system, comprises a fluid supply lumen receiving an ablation fluid from an external fluid source and a fluid chamber containing a therapeutic agent in combination with an impeller pumping the ablation fluid but of the cassette via to a fluid delivery lumen when the cassette is in a first configuration and pumping the therapeutic agent out of the cassette via the fluid delivery lumen when the cassette is in a second configuration. | 2014-04-24 |
20140114236 | Pressure Control in Phacoemulsification System - A surgical system comprises a pressurized irrigation fluid source; an irrigation line fluidly coupled to the pressurized irrigation fluid source; a hand piece fluidly coupled to the irrigation line; an irrigation pressure sensor located at or along the pressurized irrigation fluid source or irrigation line; and a controller for controlling the pressurized irrigation fluid source. The controller controls the pressurized irrigation fluid source based on a reading from the irrigation pressure sensor and an estimated flow value modified by a compensation factor. | 2014-04-24 |
20140114237 | Pressure Control in Phacoemulsification System - A surgical system comprises a pressurized irrigation fluid source; an irrigation line fluidly coupled to the pressurized irrigation fluid source; a hand piece fluidly coupled to the irrigation line; an irrigation pressure sensor located at or along the pressurized irrigation fluid source or irrigation line; and a controller for controlling the pressurized irrigation fluid source. The controller controls the pressurized irrigation fluid source based on a reading from the irrigation pressure sensor and an estimated flow value modified by a compensation factor. | 2014-04-24 |
20140114238 | SYRINGE PUMP WITH IMPROVED FLOW MONITORING - A syringe pump provides a controlled metering of the medicament from a syringe by movement of the syringe plunger while also measuring flow from the syringe with a flow sensor. Simultaneous monitoring of flow command implicit in control of the syringe plunger and an actual flow provides additional safety and detection of irregularities in the delivery of the medicament. | 2014-04-24 |
20140114239 | Infusion Catheter Tip for Biologics with Reinforced External Balloon Valve - A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal separator. The separator is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter to reduce particle flocculation. An inflatable balloon, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. A reinforcing member is employed to strengthen the catheter wall under the inflatable balloon. With this arrangement, the catheter does not kink or collapse due to the pressure exerted on the catheter wall when the balloon is inflated. In one embodiment, the reinforcing member includes an annular shaped ring. In another embodiment, the separator is positioned under the balloon and acts as the reinforcing member. | 2014-04-24 |
20140114240 | DEVICE AND METHOD FOR ACTUATING A CARPULE - A device and a method are proposed for actuating a carpule, in which a piston is displaced in the carpule by means of a ram that is telescopically extensible by rotation, and in this way a liquid medicament formulation is expelled. For carrying out different processes, different operating movements are provided, particularly the operation of an operating element in different directions and/or the operation of different operating elements. This promotes simple, intuitive and safe operation. | 2014-04-24 |
20140114241 | COATING OF SURFACES FOR SUSTAINED DRUG RELEASE - The present invention relates to a method for coating a surface of a substrate with a drug for sustained release: (i) providing a substrate with a surface to be coated, (ii) depositing at least one bilayer on at least a portion of said surface, wherein one layer of the bilayer comprises a polyelectrolyte and the other layer comprises a pharmaceutically active ingredient, and wherein the two layers of the bilayer are oppositely charged under conditions of the deposition and one layer of the bilayer has a substantially different net charge under physiological conditions. The invention also pertains to substrates with microscopic or macroscopic surfaces coated with the method according to the invention. | 2014-04-24 |
20140114242 | INTRAJUGULAR BALLOON CATHETER - The present invention relates to the use of a catheter system for avoiding air embolisms in intracranial interventions and to the catheter system itself; the latter has a first and a second catheter main body, each with a longitudinal axis, a proximal end and a distal end. The catheter main bodies have several lumens and lumen openings and in each case an expandable structure for blocking the bloodstream in blood vessels. | 2014-04-24 |
20140114243 | Intraocular Injection Device - Described is a device for intraocular injection comprising a drug delivery device, a foot at a distal end of the drug delivery device for positioning the drug delivery device with respect to an injection site, and a magnifying device coupled to one of the drug delivery device and the foot for magnifying a view of the injection site. | 2014-04-24 |
20140114244 | APPARATUS AND METHOD FOR TARGETING A BODY TISSUE - An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member has a longitudinal framing member core defining a central framing member axis. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. The framing member comprises a plurality of longitudinally extending multi-segment framing strands. | 2014-04-24 |
20140114245 | APPARATUS AND METHOD FOR TARGETING A BODY TISSUE - An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. A framing member has a collapsed condition and an expanded condition. The framing member has a framing member body which includes a bulbous portion defining a maximum body footprint having proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The framing member is comprised of a plurality of framing member beams. At least three framing member beam arrays of framing member beams are arranged in non-overlapping longitudinal sequence to form at least a portion of the framing member. The framing member beams that make up the framing member substantially each have a width-to-thickness fractional ratio in the range of 0.6-3.0. | 2014-04-24 |
20140114246 | APPARATUS AND METHOD FOR TARGETING A BODY TISSUE - An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member, when deployed into an expanded condition, has a framing member body which includes a three-dimensionally bulbous portion defining a maximum body footprint in a lateral dimension and has longitudinally spaced proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The proximal body end is attached to the target catheter. A protrusion has a diameter which is smaller than the maximum body footprint diameter. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway is substantially spaced apart from the framing member body. | 2014-04-24 |
20140114247 | Injection Device - The invention relates to an injection device comprising a housing, a container holder arranged within said housing, the container holder being configured for accommodating a medicament container having a needle attached to one end thereof and a stopper sealingly and slidable arranged inside the medicament container at the other end thereof, a drive unit comprising a plunger rod and plunger drive means, the plunger drive means being slidable arranged in relation to the plunger rod, being rotationally locked to the plunger rod and being rotatable in relation to the housing, said drive unit further comprising a first energy accumulating member arranged in the interior of the housing of the injection device and adapted to accumulate and store energy, wherein said plunger drive means is operationally associated with said first energy accumulating member, wherein the plunger drive means is releasable such that due to an output torque from said first energy accumulating member, the plunger drive means are allowed to be rotated and the plunger rod is urged towards the proximal end of the injection device whereby an injection is performed, and a rotary injection indication mechanism configured for indicating to the user the progress of the injection, wherein the rotary injection indication mechanism comprises a signalling member and a drive mechanism for rotationally driving said signalling member, said signalling member being coupled to said drive mechanism, said drive mechanism being coupled to said plunger drive means at the distal end of said plunger drive means, said rotary injection indication mechanism being arranged such that the progress of injection is shown through at least one opening provided at least in a distal end surface of the housing. | 2014-04-24 |
20140114248 | POWER PACK FOR AN AUTOINJECTOR - A power pack, for use in an autoinjector to deliver a drug from a container at an injection rate includes a power pack body configured to hold a liquefied gas and a flow regulator, the power pack body further including at least one outlet through which some of the liquefied gas can exit the power pack in a gaseous state such that, during use, the flow regulator will control a rate of exit flow such that the liquefied gas in the canister is maintained at substantially its vapor pressure, while the gas leaving the outlet applies an adaptively changing force to the drug in the container so that delivery of the drug will occur at about a constant injection rate. | 2014-04-24 |
20140114249 | SELF CONTAINED SELF INFLATING REGULATED CONTAINER - A container has a first compartment, a sleeve configured to receive at least one container for holding fluid, and a second compartment coupled to the first compartment, outside of the first compartment. Disposed inside of the second compartment in a substantially sealed manner is at least one inflator configured to pump a fluid into the first compartment wherein the at least one inflator. There can be at least one fluid channel coupled to the first compartment and to the at least one inflator for allowing fluid to flow from the at least one inflator to the first compartment. | 2014-04-24 |
20140114250 | AUTOINJECTOR - An autoinjector includes a main body having a container, the container having a drug therein, a hollow needle coupled to the container through which the drug can be delivered. The autoinjector also has a power source having a liquefied gas therein as a driver, a flow regulator, and at least one outlet through which some of the driver can exit the power pack in a gaseous state. The power source and container are coupled together for operation such that, when an injection is initiated, the flow regulator will control an exit rate of the driver such that the liquefied gas in the power source is maintained at substantially its vapor pressure and the power source will adjustably apply a force to deliver the drug via the hollow needle at a delivery rate that is a constant delivery rate. | 2014-04-24 |
20140114251 | FLUID INJECTING APPARATUS - A fluid injecting apparatus includes: a cartridge portion which has a tube that transports a fluid, a plurality of fingers that press the tube, and a blocking member that blocks the tube; and a main body portion which has a cam that presses the plurality of fingers. When the cartridge portion is detached from the main body portion, the blocking member blocks the tube. When the cartridge portion is mounted to the main body portion, the cam presses at least one of the fingers such that the tube is blocked at the position of the pressed finger and the blocking of the tube by the blocking member is released. | 2014-04-24 |
20140114252 | Removable Controller for an Infusion Pump - Some embodiments of an infusion pump system include a controller device that is configured to removably attach to a pump device in a manner that provides a secure fitting, an overall compact size, and a reliable electrical connection. In particular embodiments, the controller device can be secured to the pump device in a generally side-by-side arrangement. The compact size can enhance the discreteness and portability of the infusion pump system. | 2014-04-24 |
20140114253 | Infusion Pump Assembly - An infusion pump assembly is disclosed. The infusion pump assembly includes a locking tab and a pump barrel inside a pump barrel housing, where the pump barrel accommodates a reservoir assembly. The reservoir assembly includes a reservoir and a plunger rod. The infusion pump assembly also includes a locking disc at a terminus of the pump barrel. The locking disc includes a clearance hole for the plunger rod. The locking disc also includes at least one locking tab notch in close proximity with the locking tab. The locking tab is in moveable engagement with the locking tab notch, and the reservoir moves the locking tab from a locked position to an unlocked position when the plunger rod is inserted through clearance hole. The locking disc rotates upon torque being applied to the reservoir assembly, the locking disc rotating from a non-loaded position to a loaded position with respect to the plunger rod and a drive screw. | 2014-04-24 |
20140114254 | SELF-COILING STYLET NEEDLE DEVICE - A medical device includes an elongate single-wire memory-metal body with a complete length that includes a proximal stylet length, an intermediate self-coiling stylet length, and a distal stylet length that is generally straight and non-self-coiling. The moment of force of the self-coiling stylet length is less than the moment of force of the medical endoscopy needle that is resistant to the stylet's self-coiling force. The device may further include being incorporated into an endoscopy needle system where the single-wire stylet body is disposed through a lumen of a medical endoscopy needle. | 2014-04-24 |
20140114255 | SELF-COILING STYLET NEEDLE DEVICE - A medical device includes an elongate single-wire memory-metal body with a complete length that includes a proximal stylet length, an intermediate self-coiling stylet length, and a distal stylet length that is generally straight and non-self-coiling. The moment of force of the self-coiling stylet length is less than the moment of force of the medical endoscopy needle that is resistant to the stylet's self-coiling force. The device may further include being incorporated into an endoscopy needle system where the single-wire stylet body is disposed through a lumen of a medical endoscopy needle. | 2014-04-24 |
20140114256 | System for Umbilical Catheter - A medical catheter or tube clamp or support structure that is secured to an infant and holds a medical tube in place to prevent the tube from pistoning (axially moving within the infant relative to the entry point). In one embodiment, the medical tube claim comprises a catheter securing system that further includes a base that further includes at least one base member, a tube support member integrally formed with at least one base member that allows the tube to be inserted into an umbilical cord or stub in a relationally secure manner to prevent the tube from pistoning within an infant, and at one least channel for receiving a tube or catheter of a specified size and for securely the tube or catheter. | 2014-04-24 |
20140114257 | INJECTION DEVICE PREVENTING THE RETURN OF THE PISTON WHEN THE SAFETY SYSTEM IS DEPLOYED - The present invention relates to an injection device comprising: a body receiving a product, having a needle and a piston attached to a piston rod movable between a storage position and an end-of-injection position, a sleeve for protecting the needle, movable between an initial position, where the needle is uncovered, and a final position, where the needle is covered, biasing means for moving said sleeve from its initial position to its final position, immobilization means for keeping said sleeve in its initial position, characterized in that: said piston rod comprises a first portion and a second portion, said second portion being able to switch between a locked position, in which said second portion is fixed to said first portion and an unlocked position, in which said second portion is movable with respect to said first portion on a predetermined distance along the longitudinal axis of said piston rod. | 2014-04-24 |
20140114258 | Medicament Injection Device and Priming Operation - A medicament delivery device for the administration of one or more drug agents is described. The device has a priming mode and a drug delivery mode for administering delivery of the drug agents. The device includes a controller operative for controlling the device to perform a priming operation, and a user interface for activation of the priming operation. The controller is operative to perform the priming operation by way of a plurality of intermittent doses of medicament, the number of intermittent doses being dependent on the activation of the user interface. | 2014-04-24 |
20140114259 | FEEDING TUBE EXTENSION - A feeding tube extension may be used to extend the length of a feeding tube. The feeding tube extension may comprise an extension tube and a connector configured to be inserted into a feeding port of the feeding tube. So the flow of fluids is not unduly restricted, an inner diameter of the extension tube and a diameter of a connector lumen may be selected to be a predetermined size relative to the a diameter of a feeding tube lumen. A feeding syringe interface may facilitate use of a feeding syringe with the extension tube. Various mechanisms may be used to seal the extension tube when feeding is complete. A right-angle bolster and catheter securing device may be configured to secure the feeding tube so that it does not kink or move and cause irritation. | 2014-04-24 |
20140114260 | MEDICAL TUBE - The present invention provides a medical tube mainly comprising a thermoplastic resin wherein the surface contacting the blood has been subjected to a heparinizing treatment and wherein quality defect due to whitening and oil defect is reduced. | 2014-04-24 |
20140114261 | METHOD AND DEVICE FOR DISPENSING A LIQUID FROM A COLLAPSIBLE CONTAINER - A method and device for dispensing a liquid from a tip includes a support structure, a cartridge, and a drive unit. The support structure is adapted for supporting a collapsible container having a connector end and a closed end. The support structure includes a liquid passage adapted for fluid communication with the collapsible container for selectively discharging the liquid. The cartridge includes an actuator selectively movable from a first position to the second position via the operatively connected drive unit. At least a portion of the actuator moves toward the connector end when moving from the first position to the second position. The actuator is adapted for gradually compressing the collapsible container from the closed end toward the connector end in order to discharge liquid droplets. | 2014-04-24 |
20140114262 | STICK PACK WITH APPLICATOR - Stick pack ( | 2014-04-24 |
20140114263 | REDUCED PRESSURE TREATMENT SYSTEM - A wound treatment apparatus is provided for treating tissue damage, which comprises a fluid impermeable wound cover sealed over a site for purposes of applying a reduced pressure to the site. The apparatus also can include a cover with protrusions on its surface for purposes of monitoring pressure at the site. One or more sensors can be positioned under the cover to provide feedback to a suction pump controller. The apparatus can have a miniature and portable vacuum source connected to the wound cover. | 2014-04-24 |
20140114264 | MEDICAL DRESSINGS, SYSTEMS, AND METHODS EMPLOYING SEALANTS - According to an illustrative embodiment, a system for treating a wound at a tissue site of a patient comprising a reduced-pressure source to supply reduced pressure, a drape adhering to the tissue site to cover the wound where possible leak passages between the drape and the tissue site may occur, and a seal disposed between the drape and the tissue site, is disclosed. The seal is adapted to react with a fluid to form a sealant substantially filling the passages in response to air leaking through the passages from outside the drape when reduced pressure is applied to the wound. According to another illustrative embodiment, a method for sealing a drape to a tissue site for treating a wound at the tissue site comprising applying the drape to cover the tissue site whereby passages are formed between the drape and the tissue site, positioning a seal between the drape and the tissue site wherein the seal is adapted to react with a fluid to form a sealant for substantially filling the passages, is also disclosed. | 2014-04-24 |
20140114265 | OSTOMY APPLIANCE - An ostomy appliance for attachment to a stoma, the ostomy appliance comprising: an adhesive wafer ( | 2014-04-24 |
20140114266 | Ostomy Implant System and Method - Various embodiments of an ostomy implant system are provided. A 3D-structured ostomy implant can adapt to the shape of the interface between the intestine and the abdominal wall. The implant can include a funnel-like device where a funnel neck portion can encapsulate and support the intestine and a larger funnel top can attach to and reinforce the abdominal wall. The implant can be a unitary implant constructed of a plurality of undulating strut members. | 2014-04-24 |
20140114267 | HYDROPHILIC MEDICAL DEVICES - A medical device including a plasma-treated porous substrate that is functionalized to provide a hydrophilic surface, and a process for preparing such a medical device, are disclosed. The method includes plasma treating at least a portion of a surface of a porous substrate with a gas species selected from oxygen, nitrogen, argon, and combination thereof. The gas species is configured to functionalize the surface of the medical device and form a hydrophilic surface. | 2014-04-24 |
20140114268 | VERY ABSORBENT, THIN ADHESIVE DRESSING, AND USES THEREOF FOR THE TREATMENT OF CHRONIC WOUNDS - The invention relates to an absorbent dressing comprising an adhesive silicone-coated side strip, which is particularly suitable for use in the care of chronic wounds, such as ulcers or eschars, or acute wounds, such as burns. | 2014-04-24 |
20140114269 | NOVEL WOUND DRESSING - A wound dressing and a method of making the wound dressing is described herein. The wound dressing is formed of an absorbent substrate formed of one or more layers and a low-adherence layer disposed on the substrate. The low-adherence layer can be disposed within at least a portion of the substrate. The low-adherence layer is formed of a mixture of at least one highly fluorinated polymer and at least one acidic polymer. The at least one highly fluorinated polymer has a fluorine content greater than the fluorine content of the at least one acidic polymer. | 2014-04-24 |
20140114270 | DIAPER FOR TREATMENT OF DIAPER RASH AND METHODS OF USING SUCH A DIAPER - A diaper for treatment of diaper rash and methods of using such a diaper to treat diaper rash are provided. The diaper may include a first layer having inner and outer surfaces and including a front portion, a rear portion, and a middle portion extending between the front and rear portions and configured to be positioned between the legs of a user when worn. A liquid absorbent element may be coupled to the inner surface of the first layer and disposed proximate at least the front and middle portions. An opening may be defined in the rear portion of the first layer to expose at least a portion of the user's buttocks to open air when worn. An air and liquid permeable mesh layer may be permanently or removeably attached adjacent the opening and may cover at least part of the opening. | 2014-04-24 |
20140114271 | Absorbent Article Having Activated Color Regions in Overlapping Layers - The present invention relates to an absorbent article comprising activated color regions. The absorbent article has a first layer and a second layer in overlapping relationship with one another. The first layer has a first activatable colorant and the second layer has a second activatable colorant. The first and second activatable colorants change color in response to an external stimulus applied to the overlapping layers producing activated color regions in the first and second layers that are visible from outside the layers. | 2014-04-24 |
20140114272 | Method And Apparatus For Forming An Adjustable Pant-Like Disposable Undergarment With Fully Severed Front Panel With Line Of Weakness - A method and apparatus for producing a pre-fastened adjustable pant-like disposable absorbent undergarment including a fully severed front body panel is disclosed. The method includes the steps of providing a moving web and first creating a line of weakness on the moving web at a weakening station to define a leading portion of the moving web and a trailing portion of the moving web connected at the line of weakness. The moving web then passes through an attachment assembly station to bridge the connected leading portion and trailing portion together with a fastener assembly that extends over the line of weakness. Finally, the moving web is then passed through a web breaking station to completely separate the leading portion and trailing portion of the moving web at the line of weakness, such that the leading portion and trailing portion remains bridged together by the fastener assembly. | 2014-04-24 |
20140114273 | REUSABLE HOLDER FOR ABSORBENT MATERIAL - A reusable holder for absorbent material for absorbing menstrual flow is made from a liquid permeable inner layer affixed to an outer liquid impermeable layer at the peripheral edges to form a pouch between the two layers. An opening in the inner layer provides access to the pouch so that disposable or reusable absorbent material such as paper or cloth may be placed in the pouch to absorb menstrual flow. After use, the absorbent material may be removed from the pouch via the opening so that the used absorbent material may be disposed of or washed for re-use. Wings extending from the sides of the reusable holder allow the holder to be fastened around an undergarment to keep the holder in place. Alternatively, strings are attached to the reusable holder to allow it to be worn like a g-string. | 2014-04-24 |
20140114274 | "Pre-Filled Active Vial Having Integral Plunger Assembly" - A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom. | 2014-04-24 |
20140114275 | METHODS AND APPARATUSES FOR DELIVERING MEDICAMENTS TO INTRAVENOUS FLUID - Methods, apparatuses, kits and systems are disclosed that allow a transfer of medication from a manufacturer's vial, ampoule or other container through a closed system transfer to an intravenous apparatus and into a patient, while reducing additional steps, procedures, components required for the same transfer procedure to reduce sources of human error and medical administered errors. | 2014-04-24 |
20140114276 | RECONSTITUTION AND APPLICATOR SYSTEM FOR WOUND SEALANT PRODUCT - A system for mixing or reconstituting agents including engageable syringe barrels, one of which having a male engagement region and the other a female engagement region. Each of the male and female engagement regions is provided with a screen. The screens are closely spaced from one another when the first and second syringe barrels are engaged with one another. The screens may take the form of a mesh, a plurality of protuberances, or cantilevered wedges having tapering thicknesses. | 2014-04-24 |
20140114277 | MEDICAMENT DELIVERY DEVICE WITH DISPENSE INTERFACE SENSOR AND METHOD CONTROLLING THE DEVICE - A medicament delivery device is shown for the administration of one or more drug agents. The device comprises a medicament cartridge retainer for holding a medicament cartridge. A dispense interface can be attached to an attachment of the device for facilitating fluidic communication from the device. Further, an interface sensor is configured to provide an output indicative of whether the dispense interface is attached to the attachment. The device also comprises a piston rod for driving a bung of the medicament cartridge, and a drive train for advancing the piston rod to the bung. A controller is configured to control the drive train to advance the piston rod towards the bung when the output of the interface sensor indicates that the dispense interface is not on the attachment. The controller is further configured to disable advancement of the piston rod when the output of the interface sensor indicates that the dispense interface is at least partially on the attachment. | 2014-04-24 |
20140114278 | INTEGRATED INSULIN DELIVERY SYSTEM WITH CONTINUOUS GLUCOSE SENSOR - Systems and methods for integrating a continuous glucose sensor | 2014-04-24 |
20140114279 | MODULATION NEURAL PATHWAYS - An administration device comprising an array of needles, one or more fluid agents, and at least one hydrogel is described. The device can simultaneously deliver a plurality of fluid agents along respective axes into a tissue. The use of hydrogel leads to constrained delivery of the fluid agents. The constrained delivery of an agent is also achieved by depositing a drug implant into a tissue. The effect of an agent on the tissue can be evaluated thereafter. In addition, the invention is directed to treating muscle diseases by delivering a therapeutic agent in vivo, and the use of reporter tissues for candidate drug evaluation, detecting and characterizing resistance. | 2014-04-24 |
20140114280 | MATERIALS AND METHODS FOR REPAIR OF CARTILAGE DEFECTS - In one embodiment, the present invention includes a method for repairing a cartilage defect including: preparing a cartilage defect by removing unwanted or damaged tissue; creating at least one perforation into or through subchondral bone, below and/or adjacent to the cartilage defect to induce the flow of bone fluid; allowing the bone fluid to bleed through the at least one perforation up into the cartilage defect to fill at least a portion of the cartilage defect; and applying a biomaterial into the defect to produce a clot for cartilage regeneration. | 2014-04-24 |
20140114281 | LAUNCHER FOR ANIMAL TREATMENT - A launcher for remotely treating an animal is described. The launcher having a first chamber adapted to receive a first dosage projectile having a first calibre, a second chamber adapted to receive a second dosage projectile having a second caliber smaller than the first calibre, a launcher barrel comprising a first cooperating caliber facilitating launching of the first dosage projectile, an adaptor comprising a second cooperating caliber facilitating launching of the second dosage projectile, and a propulsion assembly for propelling the dosage projectiles. An adaptor is also described, for adapting the launcher to launch dosage projectiles of calibers other than those associated with the launcher barrel. | 2014-04-24 |
20140114282 | Patch-Sized Fluid Delivery Systems and Methods - A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device. | 2014-04-24 |
20140114283 | NURSE CONTROLLED ACCESS OF MEDICATION PUMP - A method of distributing medication is disclosed herein. The method includes the step of opening a fluid pathway for delivering fluid intravenously to a patient. The method also includes the step of placing a medication pump in fluid communication with the pathway. The method also includes the step of locking a user interface of controls for the medication pump to place the medication pump under the exclusive control of medical professionals. | 2014-04-24 |
20140114284 | INTEGRATED SYRINGE DEVICE WITH SELF-CAPPING CONNECTOR - An embodiment in accordance with the present invention provides an integrated syringe-device which can store a volume of fluid for infusion, can connect via an air-tight connector to another device (such as a luer connector), can flush fluid through the connector into the other device, and can deliver a cap that forms an air-tight closure to the device connector. | 2014-04-24 |
20140114285 | BONE MARROW ASPIRATION DEVICE - An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high MSC/ml number. An embodiment of the invention preferably comprises three syringes, wherein a first syringe is used to aspirate bone marrow from a subject, a second syringe contains an anticoagulant, and the third syringe contains a mixture of the bone marrow aspirate and the anticoagulant. | 2014-04-24 |
20140114286 | INTRODUCER SHEATH - A introducer sheath has a high centering performance that is relatively easily capable of introducing an elongated body such as a catheter into an appropriate position, and is capable of appropriately maintaining hemostasis and insertibility of a valve body. The introducer sheath includes a tubular member provided with a hollow section through which an elongated body is freely insertable, a hub that includes an inner space which communicates with the hollow section of the tubular member and is provided on a proximal side of the tubular member, a valve body that is placed in the inner space of the hub, and an annular member that contacts with the valve body to fix the valve body to the inner space and includes a through-hole into which the elongated body can be inserted. | 2014-04-24 |
20140114287 | CATHETERS WITH ENHANCED FLEXIBILITY AND ASSOCIATED DEVICES, SYSTEMS, AND METHODS - A neuromodulation catheter includes an elongate shaft and a neuromodulation element. The shaft includes two or more first cut shapes and two or more second cut shapes along a helical path extending around a longitudinal axis of the shaft. The first cut shapes are configured to at least partially resist deformation in response to longitudinal compression and tension on the shaft and torsion on the shaft in a first circumferential direction. The second cut shapes are configured to at least partially resist deformation in response to longitudinal compression on the shaft and torsion on the shaft in both first and second opposite circumferential directions. | 2014-04-24 |