17th week of 2022 patent applcation highlights part 8 |
Patent application number | Title | Published |
20220125656 | METHODS AND APPARATUS FOR CELL AND GENE THERAPY AT POINT-OF-CARE LOCATION - Methods and apparatus for producing a treatment dose of engineered cells for individual patients at the point-of-care location. In some embodiments, a patient treatment system includes a mobile cell and gene processing station that provides individualized patient treatments at point-of-care locations. The cell and gene processing station may include a patient chamber configured to isolate a patient from an external environment, a first environment controller to adjust environmental parameters of the patient chamber, a processing chamber configured to isolate processing of patient cells from the external environment, a second environment controller to adjust environmental parameters of the processing chamber, a first apparatus configured to receive at least one blood sample from the patient, a second apparatus configured to process the blood sample, and a third apparatus configured to perform cell and gene engineering on the blood sample to create a treatment dose for the patient. | 2022-04-28 |
20220125657 | DISEASE TRANSMISSION PREVENTING MASSAGE TABLE COVER - A cover for covering a face cradle on a massage table includes a cover body for attachment to the face cradle and a matter catching means attached to the cover body. The matter catching means includes a bag-like body for sealing a face opening in the face cradle and preventing particles such as droplets and droplet nuclei expelled from a mouth and/or nose of the user from flowing therethrough. The cover is thus used for preventing disease transmission through pathogenic matter expelled from the mouth and/or nose of the user. | 2022-04-28 |
20220125658 | Surgical Table Top Accessory with Sacral Offloading Attachment - An improved surgical table top accessory with a sacral offloading attachment. | 2022-04-28 |
20220125659 | DEVICE FOR TRANSPORTING A COFFIN - A device for transporting a coffin is described, composed of a supporting frame approximately covered by the coffin, comprising a plurality of sliding shelves ( | 2022-04-28 |
20220125660 | VIBRATING STATIONARY EXERCISE MACHINE - The invention provides an exercise machine ( | 2022-04-28 |
20220125661 | Patient-Worn Therapeutic Apparatus - A patient-worn therapeutic apparatus that includes a boot, a plate, and a selectively inflatable bladder. The boot is configured to accommodate a patient's foot and the plate is pivotally disposed within the boot. By one approach the pivot point is disposed proximal to the foot's arch when the patient's foot is accommodated by the boot. The selectively inflatable bladder is disposed on an underside of the plate and is configured to cause the plate to selectively pivot the patient's foot towards the patient when the patient's foot is accommodated by the boot. | 2022-04-28 |
20220125662 | FLEXIBLE EXOSUIT FOR ASSISTIVE MOBILITY - An exosuit includes a first structure including a series of link elements joined together by joints. The series of link elements extends along a length of the first structure. The joints are configured to flex such that, when the exosuit is worn by a user, the first structure at least partially conforms to a shape of the user's anatomy at a first side of the first structure that extends along the length. The joints restrict flexing that would deform a second side of the first structure extending along the length of the first structure. The exosuit includes a second structure and an actuator coupled to the first structure and the second structure. The actuator causes movement of the first structure relative to the second structure. The exosuit includes an attachment portion to attach the exosuit to the user with the first side of the first structure facing toward the user. | 2022-04-28 |
20220125663 | Hands-Free Walking Devices and Methods - Hands-free walking devices and methods of constructing the same are described herein. The devices can include a receiving member to receive a portion of a patient's leg above a patient's knee and one or more hinges connected to the receiving member. One or more vertical members can be each connected to one of the hinges. A ground-contact member can be connected to the vertical members. The receiving member can transfer at least a portion of the patient's weight through the vertical members to the ground-contact member. The hinges can rotate about an axis about which the patient's knee also rotates while walking to support a natural gait. | 2022-04-28 |
20220125664 | FOUR-LEGGED ANIMAL WHEELCHAIR - A four-legged animal wheelchair | 2022-04-28 |
20220125665 | MASSAGE DEVICES, MASSAGE ELEMENTS, AND METHODS FOR RELIEVING SOFT TISSUE PAIN AND TENSION - A massage device that includes a wall-mountable support structure and one or more massage elements. The one or massage elements may include a first massage element, a second massage element, and a third massage element. The first massage element has massage heads positioned to provide massage to a user's cervical paraspinal muscles, trapezius muscles, deltoid muscles, and rhomboid muscles. The second massage element has massage heads positioned to provide massage to the user's latissimus dorsi muscles and thoracic paraspinal muscles. The third massage element has massage heads positioned to provide massage to the user's thoracic paraspinal muscles, oblique muscles, and gluteus maximus muscles. | 2022-04-28 |
20220125666 | DEVICES AND METHODS FOR LYMPHEDEMA TREATMENT - Provided herein are compression devices and methods of use thereof, and methods of treatment for patients with edema. The compression device can include a sleeve having a plurality of inflatable chambers and at least one pneumatic pump that can be coupled to at least one inflatable chamber. The device can also include a portable bio impedance analyzer, a microcontroller and a battery. The battery can power the microcontroller and the at least one pneumatic pump and the microcontroller can control the both the portable bio impedance analyzer and the at least one pneumatic pump. The device can be used to treat a patient. Body impedance values are received from the sensors. The inflatable chambers are inflated in a sequence and to a pressure level based on the instructions from the microcontroller when the body impedance values meet a first predefined threshold. | 2022-04-28 |
20220125667 | PROCESSING GENERATED SENSOR DATA ASSOCIATED WITH DEEP VEIN THROMBOSIS (DVT) DEVICE USAGE - Processing generated sensor data of a mobile deep vein thrombosis (DVT) device may include identifying use of the mobile DVT device corresponding to a user. Sensor data associated with the user's identified use of the mobile DVT device may be generated. At least some of the generated sensor data may comprise use data associated with a duration of use of the mobile DVT device by the user. A protocol associated with use of the mobile DVT device may be processed. The generated use data and the protocol associated with use of the mobile DVT device may be correlated. Based on correlating the generated use data and the protocol, an alert associated with the generated use data and the protocol may be generated. | 2022-04-28 |
20220125668 | MULTI-PRONGED INNER STABILIZER CONFIGURATION FOR DERMA ROLLER APPARATUS - A derma roller apparatus includes a handle, a plurality of inner stabilizers, and a head connected to the handle via the plurality of inner stabilizers. The head includes an axial member positioned transverse to the handle. Furthermore, the head includes a left geometrically-shaped member positioned around the axial member to the left of the plurality of inner stabilizers. Additionally, the head includes a first plurality of needles situated around the left geometrically-shaped member. Moreover, the head includes a right geometrically-shaped member positioned around the axial member to the right of the plurality of inner stabilizers. Also, the head includes a second plurality of needles situated around the right geometrically-shaped member. | 2022-04-28 |
20220125669 | MICRO-OUTER STABILIZER CONFIGURATION FOR DERMA ROLLER APPARATUS - A derma roller apparatus has a handle, a first outer stabilizer, a second outer stabilizer, and a head connected to the handle via the first outer stabilizer and the second outer stabilizer. The head has an axial member positioned transverse to the handle. Furthermore, the head has a geometrically-shaped member positioned around the axial member in between the first outer stabilizer and the second outer stabilizer. The geometrically-shaped member has a diameter that progressively diminishes from a first end of the geometrically-shaped member to a second end of the geometrically-shaped member. Moreover, the first end of the geometrically-shaped member is proximal to the first outer stabilizer. The second end of the geometrically-shaped member is proximal to the second outer stabilizer. Finally, the derma roller apparatus has a plurality of needles situated around the geometrically-shaped member. | 2022-04-28 |
20220125670 | MASSAGE HEAD UNIT, VIBRATION ASSEMBLY AND SMART WEARABLE DEVICE - A massage head unit, a vibration assembly and a smart wearable device, including: a soft rubber base plate, a plurality of vibrating members, a plurality of soft rubber massage heads, and a plurality of soft rubber pleated bodies capable of stretching and deforming in a axial direction of each massage head; the base plate, the pleat bodies and the massage heads are integrally molded by injection molding, the base plate is provided with a plurality of through holes penetrating therethrough, and the through holes, the pleated bodies and the massage heads are in one-to-one correspondence, each massage head is provided with a mounting cavity mounted with at least one vibrating member, each pleated body is connected to a bottom of the massage head and an edge of the through hole, such that each of the massage heads is floating and supported on the edge of the through hole. | 2022-04-28 |
20220125671 | SYSTEM AND METHOD FOR PROMOTING HEALING WITH TOPICAL APPLICATION OF VIBRATION - A vibration appliance and method for providing vibration to a portion of an animal, the method including providing a pair of CR2450 batteries on opposite ends of a hot glue formed collection of switch, a vibrator motor, and connections therebetween, where one connection is a movable magnet which can be used to selectively connect batteries at opposite ends of the vibration appliance by manually moving a wire coupled at one end to the magnet and at another end to a switch between couplings with different batteries so that during storage the device has a long battery shelf life as no batteries are coupled at both terminals to electronic components. | 2022-04-28 |
20220125672 | COOLING ATTACHMENT MODULE FOR FACIAL TREATMENT DEVICE - A cooling attachment module for use with a vibration therapy device that includes a housing and/or heat sink member that includes inner and outer walls and defines a central opening axially therethrough. A cooling recess is defined in an upper surface and a connection recess is defined in a lower surface of the heat sink member. A cover member is secured over the cooling recess. A controllable temperature element is positioned on an upper surface of the heat sink member. A spreader member is positioned on an upper surface of the controllable temperature element. An upper surface of the spreader member is positioned above an upper surface of the cover member to contact a user's body part. The controllable temperature element is configured to transfer thermal energy to a lower surface of the spreader member. A base portion that includes an electrical connector is secured under the electrical recess. | 2022-04-28 |
20220125673 | MASSAGING TOOL - In a small massaging tool, numbness in fingers, strangeness, fatigue, and other discomfort, which are caused due to vibration of a grip part that is caused by vibration of a vibration motor, are eliminated to maintain comfortable use and vibration noise is reduced. The massaging tool includes a head unit | 2022-04-28 |
20220125674 | RECOVERY AND WELLNESS POD APPARATUS - An apparatus for massage of a user in a reclined position, including a housing structure having a base portion with a user support surface for supporting the user in a reclined position, and a top cover portion that extends the full length of the base portion so that the user being disposed or the user support surface is disposed between the base portion and the top cover portion, a massage assembly disposed adjacent the user support surface, and a video display disposed on an inner surface of the top cover portion so that the video display is visible to the user disposed on the user support surface. | 2022-04-28 |
20220125675 | CPR DEVICE WITH PIVOTING SUPPORT ARM - A cardiopulmonary resuscitation (“CPR”) device having a chest compression mechanism configured to deliver CPR chest compressions to a patient, the chest compression mechanism having a rigid support arm configured to pivot about a reference line to deliver the CPR chest compressions. | 2022-04-28 |
20220125676 | MECHANICAL COMPRESSION DEVICE WITH ADJUSTABLE COMPRESSION POINT - Examples of the disclosure are directed to mechanical compression devices that can adjust a location of a compression position relative to a patient. One or more of the mechanical compression devices can adjust the compression position in an adjustment plane that is generally perpendicular to a patient. Some of the mechanical compression include support columns that have actuators that can be set asymmetrically to adjust the compression position and/or can be tilted relative to the backboard to adjust the compression position. Other examples includes mechanical compression devices that have multiple actuators that can be used to adjust the compression position as well as provide compressions. | 2022-04-28 |
20220125677 | METHODS FOR DETERMINING FLUIDIC FLOW CONFIGURATIONS IN A POOL SYSTEM - One aspect of the invention provides a computer-implemented method for controlling a swimming pool or spa system. The computer-implemented method includes: creating a data structure representing a plurality of swimming pool system components and fluidic connections between subsets of the plurality of swimming pool system components; receiving a request to control one or more of the plurality of swimming pool system components; calculating fluidic flows through the plurality of swimming pool system components based on one or more potential configurations of the plurality of swimming pool system components capable of fulfilling the request; and detecting whether the one or more potential configurations result in unsatisfactory conditions. | 2022-04-28 |
20220125678 | TRIGGER POINT ROCKER - A self-massaging tool is provided. The self-massaging tool comprises a first base layer. Further, the self-massaging tool comprises a second layer formed upon the first base layer, wherein the second layer comprises a plurality of rounded protruding structures configured to assert pressure during self-massage of the user, wherein the self-massaging tool has a curved shape providing an outward bulge around its center when the self-massaging tool is aligned with the spine of the user, and wherein the curved shape of the self-massaging tool facilitates a neutral alignment with the spine of the user. | 2022-04-28 |
20220125679 | Adjustable Bottle Support - An adjustable bottle support for a pump used in medical procedures comprises first and second support members mounted on an attachment member which is attachable to a pump body. The second support member is pivotally mounted on the attachment member for rotation between a first position in which in which the first and second support members are aligned and level with one another and a second position in which the second support member is tilted and slopes upwardly in a direction away from the first support member. | 2022-04-28 |
20220125680 | LIQUID TRANSFER DEVICE - A liquid transfer device is described. The device comprises a connector body comprising a projection portion defining a tab and an IV port arranged at a first end of the connector body, the IV port comprising an elongate connecting member projecting therefrom and defining a cutout. The projection portion is configured to be received by the elongate connecting member, and the tab is configured to mate with the cutout so as to rotationally fix the IV port relative to the connector body. | 2022-04-28 |
20220125681 | MEDICAMENT COMPOUNDING DEVICES, SYSTEMS, AND METHODS - Devices, systems, and methods used to compound a first medicament and second medicament are disclosed. The devices include a single-use or single-dose vial containing a first medicament and configured to receive an ampule containing a second medicament. The vial includes a stopper and needle configured to inject the first medicament into the ampule to compound with the second medicament. | 2022-04-28 |
20220125682 | PILL LOCATOR FOR A PILL CUTTER - A pill locator is provided. The pill locator has an edge and a hole. The edge is configured to abut a recess of the pill cutter so that the board is fixed in the recess. The hole is configured to receive a pill, a shape and a size of the hole corresponds to a shape and a size of the pill. Because the pill is fittingly positioned in the hole, the pill may not be moved with respect to the pill locator. With the edge of the board abutting the recess of the pill cutter, the pill locater may not be moved with respect to the pill cutter. As a result, the pill in the pill locater may not be moved with respect to the pill cutter, so the pill will be split into two equal pieces. | 2022-04-28 |
20220125683 | STORAGE CONTAINER FOR A STORAGE AND DISPENSING STATION AND STORAGE AND DISPENSING STATION - A storage container for a storage and dispensing station for a blister machine for separable small piece goods, such as drug portions and food supplement portions, and a storage and dispensing station are provided. The storage container includes a housing having an inside circular-cylindrical portion, a separating device arranged in the inside circular-cylindrical portion having a surface, as well as a retaining assembly. The separating device includes an electrically dischargeable discharging device, the discharging device having at least one discharging projection extending from the surface of the separating device as well as a discharging contactor coupled in an electrically dischargeable manner to the at least one discharging projection for electrically coupling the discharging device to an electrically dischargeable component of a dispensing station coupled to the storage container, the dispensing station having a drive. | 2022-04-28 |
20220125684 | SYSTEMS AND METHODS FOR PORTABLE PILL DISPENSERS WITH VARIOUS DISPENSING MECHANISMS - Portable pill dispensers are disclosed herein. The portable pill dispenser may include a container configured to house at least one pill therein, a housing attachable to the container, and a dispensing mechanism disposed within the housing. In one configuration, the dispensing mechanism includes an oscillating member configured to dispense the at least one pill from the container. | 2022-04-28 |
20220125685 | Oral Device For A Baby - An oral device for a baby is disclosed herein. The oral device includes a head portion, the head portion including one of: (i) a plurality of bristles for brushing gums and/or teeth of a baby, or (ii) a plurality of protrusions for stimulating gums and/or emerging teeth of the baby; a stop portion connected to the head portion, the stop portion sized to prevent over-insertion of the oral device into the mouth of the baby; and a handle portion connected to the stop portion, the handle portion configured to be grasped by the baby or another person for holding and/or manipulating the oral device. | 2022-04-28 |
20220125686 | TITANIUM-CONTAINING SILICATE-BASED BIOACTIVE GLASS FOR ENAMEL REMINERALIZATION - A bioactive glass composition comprising titanium homogenously incorporated and distributed throughout the glass and method of making a sol-gel or melt-derived bioactive glass, the bioactive glass increasing osteogenic differentiation and can be used for enamel remineralization in dentistry or bone tissue engineering. | 2022-04-28 |
20220125687 | DENTAL COMPOSITIONS COMPRISING NANOPARTICLES PROVIDING A REFRACTIVE INDEX DIFFERENTIAL BETWEEN POLYMERIZABLE RESIN AND FILLER - Dental compositions and methods of formulating a dental composition are described. In one embodiment, the dental composition comprises a polymerizable resin comprising one or more ethylenically unsaturated monomers or oligomers and nanoparticles. The nanoparticles have a refractive index of at least 1.600 and an average discrete or aggregate particle size of no greater than 100 nm. The dental composition further comprises inorganic metal oxide filler having a discrete or aggregate average particle size of at least 200 nm. The nanoparticles are present at a concentration to provide a refractive index differential between the cured polymerizable resin and inorganic metal oxide filler such that the contrast ratio of the dental composition is at least 40. | 2022-04-28 |
20220125688 | METHOD FOR ORAL CAVITY CARE - An oral cavity care method includes daily treatment of the oral cavity with the first and second formulations of REMARS product by alternate exposure, without rinsing the mouth with water between treatments. In this case, depending on the state of the oral cavity, sequential treatment is carried out, first with a restoring solution, to normalize the pH of the oral cavity, and then with a stabilizing solution. The method improves the effectiveness of treatment of oral cavity organs. The advantage of this method consists in the possibility of long-term treatment of the oral cavity at home after the selection of the products by the dentist. | 2022-04-28 |
20220125689 | RETINOL-CONTAINING OIL-IN-WATER EMULSION COSMETIC - An objective of the present invention is to provide a retinol-containing oil-in-water emulsion cosmetic that has excellent emulsion stability while stably retaining retinol, that also has a good fitting sensation when applied, and that has a watery and fresh feeling in use. The present invention pertains to an oil-in-water emulsion cosmetic containing (a) retinol; (b) an alkyl-modified carboxyvinyl polymer; and (c) an oil, wherein a blended amount of the (c) oil is 10% to 40% by mass relative to a total amount of the cosmetic, and the (c) oil contains at least 50% by mass of an ester oil relative to a total amount of the oil. | 2022-04-28 |
20220125690 | EXTERNAL AGENT FOR SKIN OR MUCOUS MEMBRANE AND PRODUCTION METHOD THEREOF, AND BASE FOR EXTERNAL AGENT FOR SKIN OR MUCOUS MEMBRANE - Provided is an external agent for skin or mucous membrane excellent in feeling during use despite containing petrolatum as a base. An external agent for skin or mucous membrane according to the present invention includes an oil phase, as an inner phase, that consists of petrolatum or is a liquid or a semi-solid including petrolatum with a viscosity of 5000 mPa·s or more at 25° C. and a water-insoluble functional component phase, as an inner phase, including a water-insoluble functional component, and an aqueous phase as an outer phase, in which particles of a polycondensation polymer having a hydroxyl group and/or vesicles formed of an amphiphilic substance are present at an interface between the oil phase and the aqueous phase, and at an interface between the functional component phase and the aqueous phase. | 2022-04-28 |
20220125691 | SYSTEM, METHOD, AND COMPOSITION FOR SKIN IMPROVEMENT AND TRANSIENT FLORA REDUCTION - A composition for reducing transient flora on skin and improving the condition of the skin includes Ethanol or Isopropanol in an amount that is in a range from at least 60% to about 95% v/v of the composition and a hydrophobe-in-water dispersion. The composition can be prepared by homogenizing and high-pressure high-shearing a mixture of water, humectants, and one or more hydrophobes to form a hydrophobe-in-water dispersion, separately preparing an aqueous medium having the ethanol or isopropanol, and combining hydrophobe-in-water dispersion with the aqueous medium. | 2022-04-28 |
20220125692 | NANOEMULSION COSMETIC COMPOSITION AND PROCESS FOR PREPARING SAME - The present disclosure relates to a nanoemulsion cosmetic composition including an oil phase and an aqueous phase, wherein the oil phase contains a ginseng nanopowder and an oil swollen by the ginseng nanopowder, the composition does not contain an additional surfactant, and the ginseng nanopowder is distributed uniformly in the composition. According to the present disclosure, there is provided a nanoemulsion cosmetic composition which contains a natural substance by containing a ginseng nanopowder and an oil swollen by the ginseng nanopowder in an oil phase and provides beneficial effect to skin. | 2022-04-28 |
20220125693 | WARMING CONDITIONER - A cosmetic composition comprising a first composition comprising an inorganic heat generating agent that generates a heat by mixing with water; and a second composition comprising a cationic surfactant system comprising a mono-alkyl quaternized ammonium salt cationic surfactant, a high melting point fatty compound, and an aqueous carrier; wherein the ratio of the first composition to the second composition is from about 35:65 to 98:2; the difference in viscosities between the first and second composition is less than 3.5 Pa·s; the first and second compositions are kept separate from one another until dispensed; and the cosmetic composition when dispensed has a warming benefit. | 2022-04-28 |
20220125694 | Oral Care Compositions - An oral care composition comprising zinc phosphate, stannous fluoride, an anionic polymer, and a basic amino acid, as well as methods of using the same. | 2022-04-28 |
20220125695 | INORGANIC SUNSCREEN AGENTS WITH HIGHER UV RADIATION PROTECTION - Ultraviolet radiation sun protective compositions are reported which feature micronized metal oxide inorganic particles selected from zinc oxide, titanium oxide and mixtures thereof, the inorganic particles being coated with poly[C | 2022-04-28 |
20220125696 | INFLAMMATION REDUCING COMPOSITION CONTAINING A CANNABIS SATIVA COMPOUND - A variety of personal care compositions contain one or more of a cannabinoid, a Lewis acid salt inside of a vehicle to deliver the cannabinoid to a user. The vehicle that is used depends upon where the cannabinoid is to be delivered. For example, oral care compositions contain orally-acceptable carrier(s), skin care compositions contain vehicles that are compatible with the skin, and so on. Personal care compositions can take many product forms and can be used by humans or animals. Personal care compositions include, but are not limited to, mouthwashes, toothpastes, dentifrices, tooth gels, tooth powders, tablets, rinses, subgingival gels, foams, mousses, chewing gums, lipsticks, sponges, flosses, prophy pastes, petrolatum gels, denture products, deodorants, antiperspirants, pet foods and pet chews. | 2022-04-28 |
20220125697 | MULTILAYER TYPE COMPOSITION - The present invention relates to a multilayer type composition containing the following components (A) to (D): | 2022-04-28 |
20220125698 | Oral Care Compositions and Methods of Use - This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, fluoride source, and a silica abrasive which exhibits an acid pH when measured as an aqueous slurry as well as to methods of using and of making these compositions. | 2022-04-28 |
20220125699 | TOPICAL SANITIZING FORMULATIONS AND USES THEREOF - Several embodiments disclosed herein relate to formulations having antimicrobial and/or sanitizing effects, and uses of the same. In particular, the formulations and methods of using same provide, in several embodiments, an immediate and a persistent antimicrobial effect against a broad spectrum of microorganisms. | 2022-04-28 |
20220125700 | BIO-DEGRADABLE MICROCAPSULES - Bio-degradable microcapsules with a fragrance or odorant encapsulated therein during the polymerization process are provided. The bio-degradable microcapsules are of use in fabric care or personal care formulations. | 2022-04-28 |
20220125701 | SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF - A skin care composition comprising: (i) a medium having a mixture of two or more immiscible phases; (ii) 0.1 wt. % to 10 wt. % of a terpolymer of vinyl pyrrolidone/acrylic acid/lauryl methacrylate having a relative viscosity of at least 3.3 cps; and (iii) 0.1 wt. % to 20 wt. % of at least one cosmetically/dermatologically acceptable skin care additive; wherein the skin care composition is free from surfactant(s), also discloses about skin care composition comprising surfactants. Other important embodiments of this application disclose about specific sun care compositions with surfactants/without surfactants system. In another embodiment, it also discloses about a method for providing an enhanced care to skin of humans or animals employing various compositions that are disclosed in this application. | 2022-04-28 |
20220125702 | COMPOSITION COMPRISING A FATTY SUBSTANCE, A PEG POLYMER, A DIOL AND A POLYSACCHARIDE - The present invention relates to a composition, in particular a cosmetic hair composition, comprising one or more fatty substances, one or more polysaccharides in an amount of at least 3.0% by weight of the total weight of the composition, one or more diols having a molecular weight of less than 1000, and one or more polyethylene glycols comprising from 10 000 to 200 000 oxyethylene units. The invention also relates to a process for treating keratin fibers, in particular the hair, with the composition of the invention. This invention allows in particular the shaping and/or conditioning of keratin fibers, and in particular for defining the curls of the hair and fixing the shaping of dry hair. | 2022-04-28 |
20220125703 | LIP PRODUCT FORMULATION, APPLICATOR, AND METHOD FOR MAKING SAME - Provided are lip-based compositions such as lipsticks, lip balms, and lip glosses that have favorable transparency, haze, temperature stability, hardness, taste, payoff, moisturizing effect, feel, and/or resistance to droop and/or shear. In certain embodiments, the lip-based compositions are for use with a container that exposes a substantial percentage of the surface area of the lip-based composition. Also provided are processes for production of such lip-based compositions. | 2022-04-28 |
20220125704 | COMPOSITIONS AND METHODS FOR RESHAPING KERATIN-RICH SUBSTRATES AND FORMING ADHERENT FLEXIBLE FILMS - Compositions and methods for reshaping keratin-rich substrates while forming adherent flexible films contain emulsified or soluble mixtures of silanols and hemiaminals or the reaction products of silanols and hemiaminals including silylated hemiaminals. A method for treating split-ends in hair is also described. | 2022-04-28 |
20220125705 | TOPICAL COMPOSITIONS FOR THERMAL PROTECTION AND METHODS OF MAKING THE SAME - Topical compositions for protecting the skin of a mammal from the transfer of heat from a surface are described herein. The compositions include a base formulation and additives. In some instances, the additives include thermally-insulating nanoparticles and/or microparticles, and one or more of a dimethicone, a cyclomethicone, and an amodimethicone. In some instances, the additives include a silicone acrylate emulsion, the silicone acrylate emulsion comprising a blend of about 30% of acrylates/polytrimethylsiloxy-methacrylate copolymer anionic emulsion and laureth-1 phosphate and, optionally, thermally-insulating nanoparticles and/or microparticles. In some instances, the additives include a 60% non-ionic emulsion of a polydimethylsiloxane/vinyl copolymer having a viscosity of greater than 120×10 | 2022-04-28 |
20220125706 | Microstructured Textile with Microencapsulated Compounds - A microstructured textile with microencapsulated compounds is used to enable a three part therapeutic delivery system. The microstructured textile can be turned into garments that passively deliver treatments to a user's skin. The microstructured textile has an a textile substrate, an abrasive material, and a microencapsulated compound. The textile substrate is an elastic material onto which the abrasive material is superimposed. The abrasive material removes dead skin when the microstructured textile is worn by the user. The microencapsulated compound is integrated into the textile substrate so that a therapeutic compound stored therein can be gradually released into the user's skin. Far infrared (FIR) emitting particles are integrated into the textile substrate. So, FIR radiation is applied to the user's skin to facilitate circulation. | 2022-04-28 |
20220125707 | COMPOSITIONS AND METHODS FOR HAIR REGROWTH - The disclosure provides compositions and methods for promoting hair growth and reducing hair loss using bioactive extracts of curcumin, | 2022-04-28 |
20220125708 | USE OF PEONY FLOWER EXTRACT FOR IMPROVING SKIN CONDITION - Provided is a method for skin conditioning comprising administering to a subject in need thereof a composition comprising a Dan Feng peony extract, where the Dan Feng peony extract is extracted from flowers of Dan Feng peony. The Dan Feng peony extract is used to increase the production of hyaluronic acid, maintain the structure of skin keratinocytes, and regulate the moisture content of skin cells. | 2022-04-28 |
20220125709 | GINSENG POWDER, COSMETIC COMPOSITION COMPRISING SAME AND PREPARATION METHOD THEREOF - The present disclosure relates to a | 2022-04-28 |
20220125710 | COSMETIC COMPOSITION FOR SKIN BARRIER STRENGTHENING OR MOISTURIZING COMPRISING FERMENTED RICE EXTRACTS, PINEAPPLE EXTRACTS, AND GLYCERYL GLUCOSIDE MIXTURE - The present invention relates to a cosmetic composition and/or a skin external application agent for skin barrier strengthening or moisturizing comprising fermented rice extracts, pineapple extracts and glyceryl glucoside mixture. | 2022-04-28 |
20220125711 | CANNABINOID-CONTAINING ORAL THIN FILM FORMULATIONS - The methods disclosed herein permit the synthesis of cannabinoid-containing oral thin film (OTF) strips that also contain caffeine or multiple additional active ingredients. Selection of film forming agents based on water usage coupled with low temperature mixing and low temperature drying may in various embodiments permit the incorporation of up to five additional ingredients into a cannabinoid containing OTF product. | 2022-04-28 |
20220125712 | METHODS AND COMPOSITIONS FOR TREATING MIGRAINE AND CONDITIONS ASSOCIATED WITH PAIN - The present invention relates to pharmaceutical compositions of an non-steroidal anti-inflammatory drug (NSAIDs) such as, aspirin, diclofenac, ibuprofen, ketoprofen, or naproxen, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The compositions, which can be formulated for topical administration, can provide extended release of the NSAIDs. The compositions of the invention are useful, for example, in the prophylactic treatment or treatment and/or reduction of pain, in the prophylactic treatment or treatment of headaches such as migraine headaches and symptoms of migraine headaches, and in the treatment of temporomandibular disorders (TMD). | 2022-04-28 |
20220125713 | Hematocrit Modulation Through Needle Assisted Jet Injection of Testosterone - The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted injection device. | 2022-04-28 |
20220125714 | MESOPOROUS SPONGE SPICULE AND METHODS THEREOF - A mesoporous sponge spicule, a mesoporous material is synthesized on a surface of a sponge spicule to define the mesoporous sponge spicule. | 2022-04-28 |
20220125715 | COMPARTMENTALIZED DRUG DELIVERY DEVICES - A delivery device for active pharmaceutical agents and made up of a hollow polymeric outer shape forming at least one closed internal cavity or compartment and containing a solid core of one or more active pharmaceutical agents and one or more excipients substantially unattached to the hollow polymeric outer shape is provided. Also provided are methods for production and use of this device. | 2022-04-28 |
20220125716 | POWDER PREPARATION FOR NASAL ADMINISTRATION - A powder preparation for nasal administration containing a particulate of steroid hormones having an average particle size of 50 to 300 μm as an active ingredient is prepared. | 2022-04-28 |
20220125717 | GEL AND A SUPPOSITORY AND METHODS TO PROVIDE THE GEL AND SUPPOSITORY - A gel and suppository and method to provide the gel and the suppository, are disclosed herein. The gel comprising: between 50 and 150 millimolar of lactic acid concentrate; and between 0.5 and 10 millimolar of hydrogen peroxide concentrate. The suppository comprising: between 22.5 and 67.5 milligrams of lactic acid concentrate; and between 1 and 20 milligrams of hydrogen peroxide concentrate. | 2022-04-28 |
20220125718 | STABILIZED Fc FUSION PROTEIN SOLUTIONS - There is provided, inter alia, an aqueous solution formulation comprising: (i) an Fc fusion protein; and (ii) sulfate ions at a concentration of 5-200 mM to stabilise the Fc fusion protein; which formulation is free of amino acids selected from arginine, lysine and proline, and salts thereof, and which formulation is free of magnesium ions. | 2022-04-28 |
20220125719 | ADMINISTRATION REGIMEN OF SOLUTIONS OF T4 THYROID HORMONE WITH HIGH ORAL ABSORPTION - New administration regimens of the T4 thyroid hormone are described, characterized by the use of alcohol-free, water-glycerol solutions of said hormone, administered at short temporal distance, i.e. within less than 30 minutes, typically between 15 and less than 30 minutes, from the closest consumed meal. | 2022-04-28 |
20220125720 | PERIODONTIC TREATMENT AND METHOD - Dental treatments and methods, including treating gum disease, using peroxide gel and a viscous antibacterial agent including tetracycline to chemically debride and curettage a treatment area. Treatments and methods include non-surgically scaling and root plaining the treatment area with dental tools such as periodontal scalers and/or curettes during the active period of the chemical debridement. The working surfaces of dental tools can be sharpened for optimal root and tooth surfacing during treatment. Treatment can include instructions for co-therapy by or on behalf of treatment subjects between visits and for maintenance care. | 2022-04-28 |
20220125721 | METHOD OF ENHANCING THE EFFICACY AND STABILITY OF INGREDIENTS IN SUSPENSIONS - A composition comprises a low-solubility ingredient having a particle size of at most 10 μm dispersed in a solvent. The ingredient is present in an amount greater than the saturation limit of the ingredient in the solvent. The composition passes the freeze-thaw cycling test. | 2022-04-28 |
20220125722 | LIPID FORMULATIONS WITH IMMUNOGENS - RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation. | 2022-04-28 |
20220125723 | LIPID FORMULATIONS WITH VIRAL IMMUNOGENS - RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation. | 2022-04-28 |
20220125724 | METHODS OF ADMINISTERING LIPID FORMULATIONS WITH IMMUNOGENS - RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation. | 2022-04-28 |
20220125725 | METHODS OF MAKING LIPID FORMULATIONS WITH VIRAL IMMUNOGENS - RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation. | 2022-04-28 |
20220125726 | METHODS OF MAKING LIPID FORMULATIONS WITH IMMUNOGENS - RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation. | 2022-04-28 |
20220125727 | METHODS OF ADMINISTERING LIPID FORMULATIONS WITH VIRAL IMMUNOGENS - RNA encoding an immunogen is delivered in a liposome for the purposes of immunisation. The liposome includes lipids which have a pKa in the range of 5.0 to 7.6 and, preferably, a tertiary amine. These liposomes can have essentially neutral surface charge at physiological pH and are effective for immunisation. | 2022-04-28 |
20220125728 | Strategies to Enhance Lung Cancer Treatment - A nanocarrier containing a combination of bioactive agents is provided. The nanocarrier allows for targeted delivery of the agents to cancer cells with minimized side effect. | 2022-04-28 |
20220125729 | TREATMENT OF OCULAR CONDITIONS UTILIZING A HISTONE/PROTEIN DEACETYLASE INHIBITOR - A method for treating an ocular disorder in a subject comprising administering a therapeutic agent-loaded carrier to an ocular site of the subject in need thereof, wherein the therapeutic agent is a histone deactylase inhibitor. | 2022-04-28 |
20220125730 | METHOD OF MANUFACTURING AN ORALLY DISINTIGRATING TABLET - An orally disintegrating composition having a bimodal particle size distribution, methods for its production and use thereof are provided. | 2022-04-28 |
20220125731 | CHONDROITIN SULFATE GLYCOSAMINOGLYCAN HYDROGEL MATRICES FOR THE TREATMENT OF TRAUMATIC BRAIN INJURY - Disclosed herein are compositions and methods for cellular reconstitution of photopolymerized, lyophilized, bioactive chondroitin sulfate glycosaminoglycan (CS-GAG)-based hydrogel matrices. | 2022-04-28 |
20220125732 | IBUPROFEN AND FAMOTIDINE TABLET - The invention relates to a solid, pharmaceutical composition in compressed tablet form. The tablet comprises an ibuprofen core tablet, a pair of protective barriers and a famotidine outermost coating. The ibuprofen core tablet comprises ibuprofen and one or more pharmaceutically acceptable excipients selected from disintegrants, diluents, fillers, binders, glidants and lubricants. The pair of protective barrier coatings surround the ibuprofen core tablet. The first coating comprises a methacrylic acid and ethyl acrylate copolymer, a surfactant, and hydroxypropylmethylcellulose. The second coating comprises hydroxypropylmethylcellulose, and a plasticizer. The outermost coating comprises famotidine, polyvinyl alcohol and a plasticizer. | 2022-04-28 |
20220125733 | NONGRANULATED COMPRESSED TABLETS OF MESALAMINE, AND PROCESS OF PREPARATION THEREOF - The present disclosure discloses a composition suitable for direct compression into tablets without prior granulation procedures comprising: a) mesalamine or its prodrug or derivatives thereof and b) at least one pharmaceutically acceptable excipient, wherein the composition is directly compressed into a minitablet such that largest dimension in the minitablet is range of 1.00 mm to 2.8 mm. Further disclosed is a process of preparation of composition of the present disclosure. | 2022-04-28 |
20220125734 | Stable Solid Formulation of GC-C Receptor Agonist Polypeptide Suitable for Oral Administration - Solid, stable formulations of linaclotide suitable for oral administration are described herein as are methods for preparing such formulations. The formulations described herein contain a polypeptide consisting of the amino acid sequence Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (“linaclotide”; SEQ ID NO:1) or a pharmaceutically acceptable salt thereof. The linaclotide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug. | 2022-04-28 |
20220125735 | MICROFLUIDICS DEVICE FOR FABRICATION OF LARGE, UNIFORM, INJECTABLE HYDROGEL MICROPARTICLES FOR CELL ENCAPSULATION - The devices, methods, and compositions disclosed herein accomplish robust cell encapsulation in polymer microparticles using a vertically oriented microfluidic device. A hydrophilic polymer precursor solution is flowed into a first inlet channel, which extends inward from an upper surface of the device housing. A hydrophobic fluid is flowed into a second inlet channel, which extends inward from a lower surface of the device housing. The two inlet channels meet at a junction, and an outlet channel extends away from the two inlet channels. When the two inwardly flowing streams meet at the junction, the polymer precursor solution disperses into the hydrophobic fluid. The dispersed precursor droplets are photopolymerized into microparticles as they travel through the outlet channel. The resulting microparticles are highly uniform, and are larger than conventionally formed microparticles. Cells of varying types can be encapsulated with high viability and spatial uniformity. | 2022-04-28 |
20220125736 | COMPOSITIONS AND METHODS FOR INHIBITING POST-SURGICAL ADHESIONS - In one aspect, methods are described herein employing particle compositions operable to form composite membrane for inhibition of post-surgical adhesions. Briefly, a method of treating a surgical site comprises contacting the surgical site with a particle formulation comprising targeting particles and scaffolding particles. The targeting particles and scaffolding particles are crosslinked to provide a composite membrane at the surgical site, wherein formation of post-surgical adhesions are inhibited by the composite membrane. | 2022-04-28 |
20220125737 | NANOENCAPSULATION OF ANTIGEN-BINDING MOLECULES - The present invention relates to nanospheres comprising a polymeric matrix and antigen-binding molecules esterase-releasably incorporated therein. The polymeric matrix is formed by poly(alkyl cyanoacrylates) and/or alkoxy derivatives thereof. The invention further relates to methods for preparing and compositions comprising such nanospheres. | 2022-04-28 |
20220125738 | SYSTEMS AND METHODS FOR REMOVING A COVERING FROM A BODILY SURFACE - The present disclosure provides a method of removing a cover from a bodily surface of a subject. The method may comprise applying a cover removal device to a portion of the cover that is disposed on the bodily surface of the subject, thereby generating a connection between the cover removal device and the portion of the cover. The method may comprise moving the cover removal device across the bodily surface of the subject in order to selectively remove the cover from the bodily surface and capture the cover onto the cover removal device, without the cover removal device substantially affecting or interfering with the bodily surface of the subject. | 2022-04-28 |
20220125739 | Abuse and Misuse Deterrent Transdermal Systems - An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium. The prolonged aversive agent release provides deterrence against extraction of drug from fresh and used patches and serves to prevent accidental misuse of used patches by children. The abuse deterrent and misuse deterrent patch systems can be used for transdermal delivery of therapeutically active agents and particularly those drugs that are highly prone to abuse such as opiate and opioid analgesics and stimulants. | 2022-04-28 |
20220125740 | Xanthohumol Solubilizate - In order to provide a formulation for xanthohumol which has an improved anti-inflammatory effect compared to native xanthohumol, the disclosure provides a solubilizate containing, in particular consisting of xanthohumol with a content of less than or equal to 35 wt. %, preferably less than or equal to 15 wt. %, most preferably 9 wt. % to 12 wt. %, and at least one emulsifier having an HLB value in a range between 13 and 18, in particular polysorbate 80 or polysorbate 20 or a mixture of polysorbate 20 and polysorbate 80. | 2022-04-28 |
20220125741 | SOLUBILIZATE WITH CURCUMIN AND OPTIONALLY AT LEAST ONE OTHER ACTIVE SUBSTANCE - In order to make available the health-promoting and healing properties of curcumin to the human or animal organism, also in combination with at least one further active substance, a solubilizate consists of or contains a content of curcumin equal to or smaller than 10 wt %, preferably equal to or smaller than 7.5 wt %, most preferably 6 wt %, and at least one emulsifier with an HLB value in a range below 18, preferably between 13 and 18, namely polysorbate 80 or polysorbate 20 or a mixture of polysorbate 20 and polysorbate 80, with an average diameter of the curcumin-loaded micelles ranging from 5 nm to 40 nm, preferably from 6 nm to 20 nm, most preferably from 7 nm to 10 nm, for use in particular as a dietary supplement and/or pharmaceutical drug for treating and/or preventing diseases involving inflammation, cancer and other diseases. | 2022-04-28 |
20220125742 | METHOD OF TREATING MAJOR DEPRESSIVE DISORDER - The present invention provides a method for safe and efficacious administration of esketamine. | 2022-04-28 |
20220125743 | Formulation for Inhibiting Formation of 5-HT2B Agonists and Methods of Using Same - Drug combinations and their use are disclosed. A first drug is administered in combination with a second drug. The first drug such as fenfluramine is characterized by the formation of a metabolite including 5-HT | 2022-04-28 |
20220125744 | EXPLOITING ESTROGEN RECEPTOR BETA AND TP53 INTERACTION AS A NEW THERAPEUTIC STRATEGY FOR CANCER - To induce cancer cell death, cancer cells are selected that express estrogen-receptor β (ERβ) and mutant tumor protein 53 (TP53). An agent that increases ERβ protein expression is administered to the cells to induce cell death. To treat a subject having a cancer that is characterized by cancer cells expressing ERβ and mutant TP53, an agent that increases ERβ protein expression is administered to induce cell death in the cancer cells. To increase estrogen receptor β (ERβ) expression levels in a subject having low ERβ expression levels, tamoxifen is administered to increase ERβ protein levels in the subject. To treat a subject having cancer cells expressing estrogen-receptor β (ERβ) and wildtype tumor protein 53 (TP53), an agent that inhibits ERβ and TP53 binding interaction is administered to induce cell death in the cancer cells of the subject. | 2022-04-28 |
20220125745 | PHARMACEUTICAL COMPOSITION FOR CO-ADMINISTRATION OF ACIDOSIS-INDUCING DRUG - The present invention relates to a pharmaceutical composition for administration in combination with a drug that causes acidosis. Acidosis occurs due to disrupted acid-base balance caused in a case where a large amount of acid is produced and accumulated in the body. There are many cases where acidosis occurs as a side effect associated with drugs for treating various diseases, which poses problems. The pharmaceutical composition of the present invention not only allows the intended purpose, for which a drug that causes acidosis is administered, to be maintained but also has a remarkable effect in decreasing the concentration of acid accumulated in an organism due to administration of the drug that causes acidosis. Thus, the pharmaceutical composition is expected to be widely used in the fields of medicine and health. | 2022-04-28 |
20220125746 | METHOD OF PREVENTING OR TREATING TREATMENT-INDUCED GASTROINTESTINAL INJURY - Provided herein are compositions and methods for preventing or treating gastrointestinal injury induced by chemotherapy or radiotherapy. | 2022-04-28 |
20220125747 | APPLICATION OF ACTIVE INGREDIENT WGX50 IN ZANTHOXYLUM BUNGEANUM EXTRACT - An application method of the WGX50 of active ingredient in | 2022-04-28 |
20220125748 | HISTONE ACETYLTRANSFERASE (HAT) REGULATORS AND USES THEREOF - The invention provides for compounds that are HAT activators or inhibitors. The invention further provides a method for treating neurodegenerative diseases, cancer and other malignant conditions, or to increase memory in a subject not suffering from a neurodegenerative disease by administering HAT activators or inhibitors to a subject in need thereof. The method further comprises co-administration of HD AC inhibitors with HAT activators or HD AC activators with HAT inhibitors. | 2022-04-28 |
20220125749 | TRIPLE COMBINATION FORMULATION FOR TREATMENT OF CHRONIC PAIN - The disclosure relates to use of a triple formulation comprising a histone deacytlase, a cyclodextrin and polyethylene glycol or propylene glycol, and in the treatment and management of chronic pain. | 2022-04-28 |
20220125750 | METHODS OF TREATING INJURIES OR CONDITIONS RELATED TO CNS EDEMA - The present technology is related to reducing or treating neurological swelling and related conditions with SUR1-TRPM4 channel inhibitors. In some embodiments, the methods include: reducing late neurological deterioration or preventing death, reducing cerebral midline shift, reducing the degree of disability in a subject, counteracting blood glucose levels in a subject receiving a SUR1-TRPM4 channel inhibitor, preventing brain swelling, monitoring liver enzyme activity along with treating injury or conditions related to CNS edema, or monitoring cardiac activity along with treating injury or conditions related to CNS edema. | 2022-04-28 |
20220125751 | NOVEL COMPOSITION - A composition comprising a pharmaceutically active ingredient, a solubilising agent and a thixotropic agent. | 2022-04-28 |
20220125752 | LEVODOPA DERIVATIVE AND USE THEREOF - Incorporation of L-DOPA into a carrier in a form of a block copolymer (PEG-b-poly(3,4-hydroxy-protected L-DOPA)) significantly improves the retention of the agent in the blood, thus mitigating a shortcoming associated with L-DOPA in treating Parkinson's disease. | 2022-04-28 |
20220125753 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIC STROKE - The invention is directed to methods of treating ischemic stroke by administering a therapeutically effective amount of at least one compound of Formula I or Formula II to a subject in need thereof, wherein the compound has Formula I or Formula II: | 2022-04-28 |
20220125754 | TREATING THE CAUSATIVE AGENT IN ADHESIOGENESIS - The present invention relates to a compound for use in a method of reducing the formation of heliocytes causing adhesiogenesis. An in vitro assay for the formation of heliocyte and/or the formation of adhesions is also comprised herein, as well as methods comprising the use of said in vitro assay. It also relates to a pharmaceutical composition for use in a method of reducing the formation of heliocytes comprising the compound mentioned above. | 2022-04-28 |
20220125755 | CANNABIS TIME RELEASE APPARATUS AND METHOD OF MANUFACTURE THEREOF - The invention comprises a method and apparatus for forming a Cannabis product, comprising the steps of: preparing a tetrahydrocannabinol emulsion comprising particles, the particles comprising: (1) a first peak concentration of the particles, as a function of particle size, less than nine hundred nanometers in diameter; and (2) a second peak concentration of the particles greater than nine hundred nanometers in diameter and adding the tetrahydrocannabinol emulsion to at least one of: an edible, a beverage, an additive for use in a vape cartridge, and a pre-roll, where a mixer is used to form the particles containing tetrahydrocannabinol and where the particles comprise at least one of: a micelle comprising the tetrahydrocannabinol; a droplet of the tetrahydrocannabinol; a lipid bilayer cell comprising the tetrahydrocannabinol; a mixed droplet of both the tetrahydrocannabinol and an oil; and the tetrahydrocannabinol and at least one-tenth of a percent ethanol. | 2022-04-28 |