21st week of 2021 patent applcation highlights part 22 |
Patent application number | Title | Published |
20210155521 | PREPARATION OF RAW MATERIALS FOR GLASS FURNACE - A device and to a process for the preparation and charging of starting materials for a glass furnace includes a system for carrying out a mixing of starting material powder and of liquid water producing a moistened mass of starting material powder, to a system for carrying out a mixing of cullet with the moistened mass of starting material powder producing a mixture of starting material and of cullet, known as SM/C mixture, a starting material preheater in which the SM/C mixture circulates and is heated and dried in order to produce a mass to be charged, then a system for charging the glass furnace with the mass to be charged. | 2021-05-27 |
20210155522 | EXHAUST CONDUITS FOR GLASS MELT SYSTEMS - An exhaust conduit for a glass melt system includes a corrosion resistant refractory conduit material, such as a conduit material including zirconia. The conduit can extend through a relatively dense refractory block material, such as a refractory block comprising alumina. The exhaust conduit can exhibit improved corrosion resistance in processing a variety of glass melt compositions. | 2021-05-27 |
20210155523 | UNIFORMLY PAIR SAGGED GLASS ARTICLES AND HYBRID LAMINATES - A laminate includes a first glass article having a first thickness, a first annealing point, and a first softening point, a second glass article having a second thickness, a second annealing point, and a second softening point, and an interlayer disposed between the first glass article and the second glass article. The first thickness is greater than the second thickness, the second annealing point is less than or equal to the first annealing point, and the second softening point is greater than the first softening point. | 2021-05-27 |
20210155524 | 3D GLASS-CERAMIC ARTICLES AND METHODS FOR MAKING THE SAME - Methods of forming a glass-ceramic article, the method are provided. Embodiments of the method may include initially nucleating a precursor glass composition at a first nucleation temperature and maintaining the first nucleation temperature for a pre-nucleating time period to produce a pre-nucleated crystallizable glass composition, wherein the pre-nucleated crystallizable glass composition comprises 5 wt % to 20 wt % crystalline phase ASTM C1365-18, forming the pre-nucleated crystallizable glass composition into an initial 3D shape; further nucleating the initial 3D shape for a nucleating time period to a second nucleation temperature to produce a nucleated crystallizable glass composition; and ceramming the nucleated crystallizable glass composition to a crystallization temperature and maintaining the ceramming temperature for a crystallization time period to produce the glass-ceramic article. The glass-ceramic article may have a final 3D shape is within 0.1 mm of the original design specifications. | 2021-05-27 |
20210155525 | METHOD FOR BREAKING OUT A SHEET OF GLASS - A method for breaking out a sheet of glass includes tracing a score line on a first face of the sheet of glass, the score line delimiting an exterior part and an interior part of the sheet of glass, positioning a support facing the score line on the side of the sheet of glass opposite to the first face, and breaking out by simultaneous application of at least a first force on the exterior part of the sheet of glass and of at least a second force on the interior part of the sheet of glass. | 2021-05-27 |
20210155526 | PLASMA FIBERIZATION - A method of producing fibers includes exposing an inorganic composition to a plasma plume, where the plasma plume has a temperature of at least 1500° C. and a bulk velocity of at least 350 m/s. A system for producing fibers includes a plasma torch to produce the plasma plume and a feeding device to introduce the inorganic composition to the plasma plume. | 2021-05-27 |
20210155527 | MAGNESIUM ALUMINOSILICATE GLASSES WITH HIGH FRACTURE TOUGHNESS - A glass composition includes: Si | 2021-05-27 |
20210155528 | ALUMINOSILICATE GLASSES WITH HIGH FRACTURE TOUGHNESS - A glass composition includes: Si | 2021-05-27 |
20210155529 | Y2O3-CONTAINING GLASS COMPOSITIONS, SUBSTRATES, AND ARTICLES - A glass substrate formed from a glass composition is disclosed. In embodiments, the composition comprises: from 60 mol. % to 75 mol. % SiO | 2021-05-27 |
20210155530 | ION EXCHANGEABLE ALKALI ALUMINOSILICATE GLASS COMPOSITIONS HAVING IMPROVED MECHANICAL DURABILITY - A glass composition comprises: 50.0 mol % to 70.0 mol % SiO | 2021-05-27 |
20210155531 | HIGH FRACTURE TOUGHNESS GLASSES WITH HIGH CENTRAL TENSION - A glass-based article of a composition comprising: from 48 mol. % to 75 mol. % SiO | 2021-05-27 |
20210155532 | ION-EXCHANGEABLE MIXED ALKALI ALUMINOSILICATE GLASSES - A glass composition includes from 55.0 mol % to 75.0 mol % SiO | 2021-05-27 |
20210155533 | GLASS-BASED ARTICLES WITH FRACTURE RESISTANT STRESS PROFILES - Glass-based articles comprise stress profiles providing improved fracture resistance and decreased weight gain. The glass-based articles are produced with a single-step ion exchange process. | 2021-05-27 |
20210155534 | PROCESS FOR MAKING MULTI-FIBER, PHYSICAL CONTACT FIBER FERRULE ASSEMBLIES - A method of manufacturing a fiber ferrule assembly that includes inserting an exposed end portion of a plurality of optical fibers including a core and a cladding into an array of insertion holes disposed in a glass ferrule plate. The glass ferrule plate includes a glass material that differs from a glass material of both the core and the cladding. The method further includes chemically etching the glass ferrule plate and the exposed end portion of the plurality of optical fibers using a chemical etchant for an etching time period. The glass ferrule plate etches at a first etching rate, the exposed end portion etches at a second etching rate, and the first etching rate is faster than the second etching rate such that, after the etching time period, the exposed end portion of each of the plurality of optical fibers protrude from a second surface of the glass ferrule plate. | 2021-05-27 |
20210155535 | COATED GLASS ARTICLE, METHOD OF MAKING THE SAME, AND PHOTOVOLTAIC CELL MADE THEREWITH - A coated glass article includes a glass substrate. A coating is formed on the glass substrate. The coating includes a first coating layer. The first coating layer includes fluorine doped tin oxide. A second coating layer is provided between the glass substrate and the first coating layer. The second coating layer includes silicon dioxide and at least one of phosphorus and boron. The coated glass article exhibits a haze of 2.0% or less. | 2021-05-27 |
20210155536 | GLASS AND LAMINATED GLASS - Glass for a vehicle includes a glass plate; a test-region A demarcated in the glass plate, the test-region A being specified in JIS R3212; a shielding layer provided more outwardly than the test-region A in a plan view; an information transmission/reception region demarcated within an opening portion provided in the shielding layer, and through which a device mounted in the vehicle transmits/receives information; and an infrared reflective layer positioned peripheral to the information transmission/reception region in a plan view, the infrared reflective layer having a portion that overlaps with the shielding layer in a plan view, wherein a solar direct transmittance of the test-region A is 60% or less and a solar direct reflectance of a region in which the infrared reflective layer is provided peripheral to the information transmission/reception region is greater than a solar direct reflectance of the test-region A by at least 5%. | 2021-05-27 |
20210155537 | GLASS SHEET COATED WITH A STACK OF THIN LAYERS AND AN WITH AN ENAMEL LAYER - A material includes a glass sheet coated on at least part of one of its faces with a stack of thin layers, the stack being coated on at least part of its surface with an enamel layer including zinc and less than 5% by weight of bismuth oxide, the stack further including, in contact with the enamel layer, a layer, called contact layer, which is based on an oxide, the physical thickness of the contact layer being at least 5 nm. | 2021-05-27 |
20210155538 | CHAMBERED THIN GLASS PRODUCT WITH COMPLEX SHAPE AND WITH INCREASED RESISTANCE AND THE PRODUCTION METHOD OF SAID GLASS PRODUCT - The present invention relates to a strengthening method developed for use in chambered glass products with complex shape and with thin walls and having crystalline structure and comprising SiO | 2021-05-27 |
20210155539 | GLASS PRODUCT, METHOD FOR PREPARING GLASS PRODUCT, AND GLASS PRODUCT PREPARATION APPARATUS - A glass product includes a glass substrate and first protrusion. The first protrusion is provided on the glass substrate and is with a first atom-aggregation state. The glass substrate is with a second atom-aggregation state. The first atom-aggregation state is different from the second atom-aggregation state. The present application also proposes a method for preparing the glass product and an apparatus for preparing the glass product. The glass product is irradiated with a ultra-short pulse laser on the surface of the glass substrate, so that bonds between atoms on the surface of the glass substrate are broken, thereby changing the arrangement of the atoms, and light is diffusely reflected when irradiating the surface of the glass product. | 2021-05-27 |
20210155540 | LOW-BELITE CSA CEMENT FOR CONSTRUCTION-CHEMICAL APPLICATIONS - The invention relates to a calcium sulfoaluminate cement, whereby it contains at least 90% by weight % C4A3$ in crystalline or amorphous form or as a mixture of crystalline and has amorphous parts. | 2021-05-27 |
20210155541 | POLYMER FIBERS FOR REINFORCEMENT OF CEMENT-BASED COMPOSITES - The present invention relates to a polymer composition for forming fibers for reinforcement of cement-based composites, polymer fibers made from the composition and methods of making the polymer fibers. The polymer composition comprises an olefin polymer and a bonding agent comprising vinyl alcohol based polymer, a pozzolanic material or a combination thereof. | 2021-05-27 |
20210155542 | AMPHIPATHIC MULTIFUNCTIONAL HYBRID NANOPARTICLE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF - Disclosed is an amphiphilic multifunctional hybrid nanoparticle. The nanoparticle of the present invention has a detachable hydrophilic organic polymer with both a water-soluble long chain and a hydrophobic long hydrocarbon functional group attached to the surface, wherein the body of the nanoparticle is a silica or an organofunctional group substituted silica or an organofunctional group substituted silicon-oxygen bond network, and the nanoparticle contains a free organosiloxane with hydrophobic long hydrocarbon functional groups and a fatty acid or fatty acid ester or aluminum complex of fatty acid with hydrophobic long hydrocarbon functional groups. The nanoparticle can reduce the water permeability of the cement-based material; the cement-based material has the internal hydration products and interfaces are hydrophobized, further reducing the possibility that the harmful particles erode the cement-based material through moisture penetration; furthermore, Si—Al oxides participate is beneficial to the improvement of its mechanical properties. | 2021-05-27 |
20210155543 | FLOUR BINDER FOR GYPSUM BOARD, AND RELATED METHODS, PRODUCT, AND SLURRIES - Disclosed is an acid-modified flour and a method of making the acid-modified flour. The acid-modified flour is desirably prepared using a dry milling process. A starting flour is combined with a strong acid to form a mixture. The mixture is heated. A neutralizer is added to increase the pH of the mixture. If desired, the mixture can be dried and any agglomerates can be removed. The acid-modified flour can be used as a binder in a slurry for preparing one or more gypsum layers in a gypsum board. | 2021-05-27 |
20210155544 | Cellulose-Based Aggregate Admix - What is disclosed is a cellulose-based aggregate admix product and a method for producing the aggregate admix product that includes the steps of thoroughly hydrating cellulose fibers, mixing clay and mineral particulates with a liquid to produce an emulsion, adding the emulsion to the hydrated cellulose fibers, and thoroughly impregnating the cellulose fibers with components from the emulsion and producing an aggregate admix product. | 2021-05-27 |
20210155545 | GYPSUM BOARD CONTAINING HIGH ABSORPTION PAPER AND RELATED METHODS - Disclosed are a composite gypsum board and a method of preparing composite gypsum board. The board contains at least one set gypsum layer sandwiched between two cover sheets. The set gypsum layer is formed from at least stucco and water. The stucco material generally includes a high salt impurity content, for example, when the stucco is calcined from certain sources of low-quality synthetic gypsum. For example, in some embodiments, the salts are chloride salts, e.g., sodium chloride (NaCl), potassium chloride (KCl), magnesium chloride (MgCl | 2021-05-27 |
20210155546 | CERAMIC SPHERES FROM ALUMINOSILICATES - The invention relates to a method for obtaining ceramic spheres from aluminosilicates, comprising: dry-milling a percentage of the aluminosilicates and wet-milling the remaining percentage; mixing the aluminosilicates obtained from the dry- and wet-milling processes with a binding additive; granulating same; drying the resulting granules; sieving the resulting granules in order to separate same into sub-groups; and sintering the granules obtained at a temperature between 800° and 1500° C. | 2021-05-27 |
20210155547 | DIELECTRIC CERAMIC COMPOSITION AND CERAMIC ELECTRONIC COMPONENTS - Provided is a dielectric ceramic composition including a first component and a second component, wherein the first component comprises an oxide of Ca of 0.00 mol % to 35.85 mol % an oxide of Sr of 0.00 mol % to 47.12 mol %, an oxide of Ba of 0.00 mol % to 51.22 mol %, an oxide of Ti of 0.00 mol % to 17.36 mol %, an oxide of Zr of 0.00 mol % to 17.36 mol %, an oxide of Sn of 0.00 mol % to 2.60 mol %, an oxide of Nb of 0.00 mol % to 35.32 mol %, an oxide of Ta of 0.00 mol % to 35.32 mol %, and an oxide of V of 0.00 mol % to 2.65 mol %, and the second component includes at least (a) an oxide of Mn of 0.005% by mass to 3.500% by mass and (b) an oxide of Cu and/or an oxide of Ru. | 2021-05-27 |
20210155548 | PREPARATION AND APPLICATION OF A LOW-B HIGH-RESISTANCE HIGH-TEMPERATURE THERMISTOR MATERIAL WITH WIDE TEMPERATURE RANGE - An object of the present disclosure is to provide the preparation and application of a low-B high-resistance high-temperature thermistor material with wide temperature range. The thermistor material uses CaCO | 2021-05-27 |
20210155549 | DIELECTRIC CERAMIC COMPOSITION AND CERAMIC ELECTRONIC COMPONENT - A dielectric ceramic composition including a first component and a second component. The first component comprises an oxide of Ca of 0.00 mol % to 35.85 mol % an oxide of Sr of 0.00 mol % to 47.12 mol %, an oxide of Ba of 0.00 mol % to 51.22 mol %, an oxide of Ti of 0.00 mol % to 17.36 mol %, an oxide of Zr of 0.00 mol % to 17.36 mol %, an oxide of Sn of 0.00 mol % to 2.60 mol %, an oxide of Nb of 0.00 mol % to 35.32 mol %, an oxide of Ta of 0.00 mol % to 35.32 mol %, and an oxide of V of 0.00 mol % to 2.65 mol %. The second component includes (by mass) at least (a) an oxide of Mn of 0.005% to 3.500% by mass and (b) one or both of an oxide of Cu of 0.080% by mass to 20.000% and an oxide of Ru of 0.300% to 45.000%. | 2021-05-27 |
20210155550 | SILICON NITRIDE-BASED SINTERED BODY AND CUTTING INSERT - A silicon nitride-based sintered body containing silicon nitride-based grains, which are formed of sialon grains. In the silicon nitride-based sintered body, when the size of each silicon nitride-based grain is represented by its maximum grain size, the ratio of the number of silicon nitride-based grains having a maximum grain size of 1 μm or less to the number of the entire silicon nitride-based grains is 70% or higher. Furthermore, in the distribution profile of no. % of silicon nitride-based grains with respect to maximum grain size, the maximum value of no. % (i.e., maximum no. %) of silicon nitride-based grains is 15 no. % or higher. Also disclosed is a cutting insert, which is formed of the silicon nitride-based sintered body. | 2021-05-27 |
20210155551 | METHOD FOR MANUFACTURING ZIRCONIA BLOCK FOR DENTAL PROSTHESIS HAVING LAYERED COLOR GRADIENT BY WATER ABSORPTION RATE - The present invention relates to a method for manufacturing a zirconia block for a dental prosthesis having a layered color gradient by a water absorption rate, in which the permeation degree of a coloring solution is controlled by setting a different particle size of powder for each layer of the zirconia block on the basis of the property that the amount of water absorption per hour is differentiated according to the particle size of powder, and as a result, the zirconia block is constituted so as to realize an esthetically excellent resultant product with the same color as natural teeth without carrying out the existing coloring liquid process for zirconia. | 2021-05-27 |
20210155552 | PROCESS FOR MANUFACTURING A FIBROUS PREFORM FILLED WITH PARTICLES - A process for manufacturing a fibrous preform filled with particles, includes forming the filled preform by compacting a stack of a plurality of fibrous strata impregnated by a suspension of ceramic oxide particles in a liquid medium, wherein the liquid medium includes at least one compound having a saturated vapor pressure of less than 2.3 kPa at 20° C., this compound being present in a weight content of greater than or equal to 30% relative to the total weight of the suspension. | 2021-05-27 |
20210155553 | PREFORM FOR CERAMIC MATRIX COMPOSITE, METHOD OF MAKING A CERAMIC MATRIX COMPOSITE AND CERAMIC MATRIX COMPOSITE - Disclosed is a preform for a ceramic matrix composite including direct channels extending from an exterior surface of the preform to an interior space of the preform wherein the direct channels are free of char. | 2021-05-27 |
20210155554 | Granules - Plurality of granules comprising a ceramic core having an outer surface and a shell on and surrounding the core, wherein the core comprises first ceramic particles bound together with a first inorganic binder, wherein the first inorganic binder comprises reaction product of at least alkali silicate and hardener, wherein the shell comprises at least a first concentric layer, wherein the first layer comprises a second inorganic binder and optionally second ceramic particles, wherein if present the second ceramic particles are bound together with the second inorganic binder, wherein the second inorganic binder comprises reaction product of at least alkali silicate and hardener, wherein for a given granule, the first ceramic particles are present in a first weight percent with respect to the total weight of the core and the second ceramic particles, if present in the first layer of the same granule are in a second weight percent with respect to the total weight of the first layer, wherein for a given granule, the first weight percent is greater than the second weight percent, and wherein the granules have a minimum Total Solar Reflectance of at least 0.7. The granules are useful, for example, as roofing granules. | 2021-05-27 |
20210155555 | SHEAR BINDER AGGLOMERATES ENABLING HIGH POROSITY IN CERAMIC HONEYCOMB BODIES - A ceramic precursor mixtures for extrusion and firing into porous ceramics. The ceramic precursor mixtures include ceramic beads and green inorganic shear binder agglomerates. The green inorganic shear binder agglomerates can include inorganic filler particles and a polymeric binder. The green inorganic shear binder agglomerates can deform under an applied shear stress during mixing and/or extrusion such that they are smeared into a plurality of interbead gaps between adjacent ceramic beads or pore former particles. During firing, the smeared green inorganic shear binder agglomerates can sinter and react to form ribbons extending between, and interconnecting adjacent ceramic beads. | 2021-05-27 |
20210155556 | MICROFIBER-REINFORCED HIGH-STRENGTH CONCRETE - A method is provided for producing a microfiber-reinforced high-strength concrete, comprising a cement matrix with a microfiber addition. The fiber elements have a shape-memory alloy. The method has at least the following steps: training a fiber shape of the fiber elements at a temperature above a transition temperature, wherein the fiber shape allows the fiber elements to latch; cooling the trained fiber elements; plastically deforming the fiber elements from the trained fiber shape into an intermediate form by means of which the fiber elements are prevented from latching; introducing the fiber elements into the cement matrix in order to form a fresh concrete; and casting the fresh concrete and heating the fresh concrete to the transition temperature such that the fiber elements reform into the fiber shape, thereby latching the fiber elements. The invention additionally relates to a microfiber-reinforced concrete which is produced using such a method. | 2021-05-27 |
20210155557 | Asphalt Cement Concrete Interlayer System for Reflective Crack Relief - An asphalt-cement concrete (“ACC”) interlayer formed of a plant-mix material reinforced with aramid fibers, deposited at a thickness of at least one inch (1″) over a Portland-cement concrete (“PCC”) or ACC base, can extend the service life of a hot-mix asphalt (“HMA”) surface layer installed over the interlayer by retarding or preventing “reflected” cracks—cracks in the surface layer that correspond to cracks, damage and irregularities in the PCC or ACC base. When the surface layer's useable life has expired, it can be removed and replaced, and the interlayer can continue to protect the new surface layer. | 2021-05-27 |
20210155558 | SLURRY INFILTRATION HEAT TREATMENT METHOD - A method of producing a melt infiltrated ceramic matrix composite (CMC) article that includes the steps of: forming a ceramic fiber preform; optionally, rigidizing the ceramic fiber preform with a fiber interphase coating via a Chemical Vapor Infiltration (CVI) process, infiltrating a ceramic slurry into the porous body or preform, conducting one or more secondary operations, and finally, melt infiltrating the preform with molten silicon or a silicon alloy to form the CMC article. The infiltration of a ceramic slurry into a ceramic fiber preform to form a green body is performed along with the use of convection and/or conduction as heat transfer mechanisms, such that the ceramic slurry does not require the incorporation of a pre-gelation material in order for the slurry to remain within the green body during subsequent processing steps. | 2021-05-27 |
20210155559 | METHOD AND SYSTEMS FOR ISOLATION AND/OR SEPARATION OF TARGET PRODUCTS FROM ANIMAL PRODUCED WASTE STREAMS - The present invention relates to separation methods and systems for converting high concentrations of animal wastes into useful products, wherein the separation of the desired useful products is conducted with a cross-flow filtration system having the ability to the separate desired useful energy and/or products from both viscous and non-viscous medium. | 2021-05-27 |
20210155560 | METHOD FOR OBTAINING A UREA-BASED FERTILIZER COMPOSITION COMPRISING A (THIO)PHOSPHORIC ACID TRIAMIDE UREASE INHIBITOR VIA PROVIDING A LIQUID OR SOLID PREMIX WITH SPECIFIC WEIGHT RATIOS - Method for obtaining a fertilizer composition comprising (iii) at least one urea-containing fertilizer (1); and (iv) at least one (thio)phosphoric acid triamide (2) according to general formula (I) wherein X | 2021-05-27 |
20210155561 | METHOD AND REAGENT FOR DEOXYFLUORINATION - A safe, simple, and selective method and reagent for deoxyfluorination is disclosed. With the method and reagent disclosed herein, organic compounds such as carboxylic acids, carboxylates, carboxylic acid anhydrides, aldehydes, and alcohols can be fluorinated by using the most common nucleophilic fluorinating reagents and electron deficient fluoroarenes as mediators under mild conditions, giving corresponding fluoroorganic compounds in excellent yield with a wide range of functional group compatibility and easy product purification. For example, directly utilizing KF for deoxyfluorination of carboxylic acids provides the most economical and the safest pathway to access acyl fluorides, key intermediates for syntheses of peptide, amide, ester, and dry fluoride salts. | 2021-05-27 |
20210155562 | Design of an Ethylene Oligomerization/Trimerization/Tetramerization Reactor - A process includes periodically or continuously introducing an olefin monomer and periodically or continuously introducing a catalyst system or catalyst system components into a reaction mixture within a reaction system, oligomerizing the olefin monomer within the reaction mixture to form an oligomer product, and periodically or continuously discharging a reaction system effluent comprising the oligomer product from the reaction system. The reaction system includes a total reaction mixture volume and a heat exchanged portion of the reaction system comprising a heat exchanged reaction mixture volume and a total heat exchanged surface area providing indirect contact between the reaction mixture and a heat exchange medium. A ratio of the total heat exchanged surface area to the total reaction mixture volume within the reaction system is in a range from 0.75 in | 2021-05-27 |
20210155563 | Production and isolation of monocyclic aromatic compounds from a gasification gas - The present invention concerns a process and system for producing and isolating a fraction of monocyclic aromatic compounds from a gasification gas. The process comprises (a) contacting the gas with a catalyst capable of converting ethylene and possibly other unsaturated hydrocarbons into monocyclic aromatic compounds; and (b) isolating monocyclic aromatic compounds from the gas originating from step (a). The present invention is ideally suited for treatment of gas from coal, biomass or waste gasification, which comprises substantial amounts of ethylene as well as monocyclic aromatic compounds. Treatment according to the invention first converts the ethylene into further monocyclic aromatic compounds, and the entire fraction of monocyclic aromatic compounds is isolated to obtain a valuable product. | 2021-05-27 |
20210155564 | METHOD FOR PRODUCING ACETYLENE AND SYNGAS - A process for producing acetylene and syngas by partial oxidation of hydrocarbons with oxygen, involving: separately preheating a hydrocarbon and a oxygen-comprising input stream; mixing in a mass flow ratio of the oxygen-comprising to hydrocarbon stream at an oxygen number no more than 0.31; feeding the streams via a burner block to a combustion chamber and therein partially oxidizing the hydrocarbon(s) to a cracking gas; quenching the cracking gas to 80 to 90° C. downstream by injecting an aqueous quench medium to obtain a process water stream- | 2021-05-27 |
20210155565 | Selective Hydrogen Removal - Processes are provided for the removal of hydrogen from a mixture. The process can be performed by contacting a mixture comprising hydrogen, oxygen, and one or more organic compounds with a synthetic zeolite to produce water or steam. The synthetic zeolite can include Si and Al and has a SiO | 2021-05-27 |
20210155566 | ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME - The present disclosure provides an organic compound of following formula and an organic light emitting diode and an OLED device including the organic compound. | 2021-05-27 |
20210155567 | PROCESS FOR THE PRODUCTION OF 2,3,3,3-TETRAFLUOROPROPENE - The present invention relates to a process for the gas-phase production of 2,3,3,3-tetrafluoropropene, comprising the steps: i) providing a composition A comprising 2-chloro-3,3,3-trifluoropropene and/or 2,3-dichloro-1,1,1-trifluoropropane and/or 2-chloro-1,1,1,2-tetrafluoropropane or a composition B comprising 1,1,1,2,2-pentafluoropropane and/or 1,1,1,2,3-pentafluoropropane; ii) placing said composition A in contact with hydrofluoric acid in the presence of a catalytic composition comprising a chromium-based catalyst or placing said composition B in contact with a catalytic composition comprising a chromium-based catalyst to produce a composition C comprising 2,3,3,3-tetrafluoropropene, characterized in that step ii) is performed at a temperature of between 310° C. and 450° C. and in that the temperature of step ii) is controlled so as not to exceed 450° C.; and when said catalyst is deactivated, the temperature of step ii) is increased in increments from 0.5° C. to 20° C. on condition that the temperature does not exceed 450° C. | 2021-05-27 |
20210155568 | METHOD FOR FABRICATING POLYOLS - A high-activity double-metal-cyanide catalyst, a method for fabricating the same, and applications of the same are disclosed. An organic complexing ligand, which is formed via mixing fatty alcohols and alicyclic carbonates, is used to generate a high-activity double-metal-cyanide catalyst. The high-activity double-metal-cyanide catalyst includes at least one double-metal-cyanide compound, at least one organic complexing ligand, and an optional functionalized compound. The double-metal-cyanide catalyst of the present invention has a higher activity than the conventional double-metal-cyanide catalysts. The polyols generated by the present invention has an insignificant amount of high-molecular-weight compounds. | 2021-05-27 |
20210155569 | METHOD FOR PRODUCING AT LEAST ONE OF UNSATURATED ALDEHYDE ANDUNSATURATED CARBOXYLIC ACID AND CATALYST FOR PRODUCING AT LEASTONE OF UNSATURATED ALDEHYDE AND UNSATURATED CARBOXYLIC ACID - Provided is a method for producing at least one of an unsaturated aldehyde and an unsaturated carboxylic acid from an alkene by an oxidation reaction, in which a n-layered catalyst layer (n≥2) is provided in a gas flow direction in a reaction tube, two or more kinds of catalysts having different activities are used; and the catalysts are packed in such a manner that dT≤20° C. is satisfied, when a difference between a temperature PT | 2021-05-27 |
20210155570 | RIPENING OF 1,4-BIS (4-PHENOXYBENZOYL)BENZENE - A method for manufacturing 1,4-bis(4-phenoxybenzoyl)benzene, including: reacting terephthaloyl chloride with diphenyl ether in a reaction solvent and in the presence of a Lewis acid, so as to obtain a product mixture comprising a 1,4-bis(4-phenoxybenzoyl)benzene-Lewis acid complex; putting the product mixture in contact with a protic solvent, so as to obtain a first phase containing the Lewis acid and a second phase containing 1,4-bis(4-phenoxybenzoyl)benzene; heating at least the second phase up to a maximum temperature, followed by cooling the second phase down to a separation temperature; subjecting at least the second phase to a solid/liquid separation step at the separation temperature, so as to recover solid 1,4-bis(4-phenoxybenzoyl)benzene. | 2021-05-27 |
20210155571 | PURIFICATION OF 1,4-BIS (4-PHENOXYBENZOYL)BENZENE BY CENTRIFUGAL FILTRATION - A method for manufacturing 1,4-bis(4-phenoxybenzoyl)benzene, including: reacting terephthaloyl chloride with diphenyl ether in a reaction solvent and in the presence of a Lewis acid, so as to obtain a product mixture comprising a 1,4-bis(4-phenoxybenzoyl)benzene-Lewis acid complex; putting the product mixture in contact with a protic solvent, so as to obtain a first phase containing the Lewis acid and a second phase containing 1,4-bis(4-phenoxybenzoyl)benzene; subjecting at least the second phase to a solid/liquid separation step by centrifugal filtration, so as to recover solid 1,4-bis(4-phenoxybenzoyl)benzene. | 2021-05-27 |
20210155572 | ISOMERIZATION METHOD OF CYCLOHEXANE DICARBOXYLIC ACID - Provided is an isomerization method of cyclohexane dicarboxylic acid using zirconia or titania as an isomerization catalyst. | 2021-05-27 |
20210155573 | ORGANIC AMINE COLLECTION METHOD - A method is provided for collecting a compound of formula (III) (in which R31 is a monovalent to trivalent organic group and n31 is an integer of 1 to 3) from a liquid phase component that is formed as a by-product in a method for producing a compound of general formula (I) (in which R11 is a monovalent to trivalent organic group and n 11 is an integer of 1 to 3), wherein the collection method contains steps (1) to (3) or steps (A) and (B), and step (4). Step (1): a step for reacting the liquid phase component with at least one active hydrogen-containing compound in a reactor. Step (2): a step for returning a condensed liquid obtained by cooling gas phase components in the reactor to the reactor. Step (3): a step for discharging gas phase components that are not condensed in the step (2) to the outside of the reactor. Step (A): a step for mixing the liquid phase component, water, and a compound of general formula (III). Step (B): a step for reacting the liquid phase component with water inside the reactor. Step (4): a step for discharging, as a liquid phase component inside the reactor, the reaction liquid containing the compound of general formula (III) to the outside of the reactor. | 2021-05-27 |
20210155574 | METHOD FOR SYNTHESIZING AMINES - The invention relates to a process for preparing certain amines, wherein, in a first step, a corresponding amino alcohol is reacted with a suitable carbonyl compound and then, in a second step, the intermediate obtained in the first step is reacted with a suitable amine component to form the desired amine. | 2021-05-27 |
20210155575 | PROCESS FOR PREPARATION OF AMINO ALCOHOLS - A process for the preparation of amino alcohols includes condensing a compound of Formula (II), a stereoisomer, a tautomer, or a salt thereof with a compound of Formula (IIIa) or Formula (IIIb), a stereoisomer, a tautomer, or a salt thereof to form a condensation product; hydroxylating or acyloxylating the condensation product in the presence of an oxidant to obtain a hydroxylation or acyloxylation product; and subjecting the hydroxylation or acyloxylation product to one or more subsequent reactions comprising a hydrolysis reaction, alcohol deprotection, an amino lysis reaction, or a combination of two or more thereof to obtain an amino alcohol of Formula (I). | 2021-05-27 |
20210155576 | NEPRILYSIN INHIBITORS - In one aspect, the invention relates to compounds having the formula XII: | 2021-05-27 |
20210155577 | CRYSTALLINE TRANILAST SALTS AND THEIR PHARMACEUTICAL USE - The invention relates to crystalline tranilast salts. The crystalline tranilast salts, their preparation and their characterization are described and shown in the figures. The invention relates to pharmaceutical compositions containing a crystalline tranilast salt of the invention and a pharmaceutically acceptable carrier. The invention also relates to methods of treatment and the use of a therapeutically effective amount of a crystalline tranilast salt of the invention for treatment. The invention also relates to a method of preparing a liquid pharmaceutical composition comprising the step of dissolving a crystalline tranilast salt of the invention in a pharmaceutically acceptable solvent and to liquid pharmaceutical compositions prepared according to that method. | 2021-05-27 |
20210155578 | COMPOUNDS FOR TREATING INFECTIONS - The invention relates to hydrazide compounds and their use in medicine, particularly in treating and/or preventing infections caused by a fungus. | 2021-05-27 |
20210155579 | CYANOCARBON COMPOSITIONS - The disclosure relates to the cyanocarbon compositions and processes for producing the same. The cyanocarbon compositions comprise tricyanohexane and one or more coproducts of the tricyanohexane production reaction. Exemplary coproducts include tetracyano compounds, cyanoalkenes, cyanooximes, cyanoamides, and combinations thereof. | 2021-05-27 |
20210155580 | BRANCHED URETHANE METHACRYLATE COMPOUNDS AND USE THEREOF - Branched urethane methacrylate compounds are useful as backbone resins for increasing the performance of a fastening material. Furthermore, reactive resins and reactive resin components containing such compounds are useful for chemical fastening. | 2021-05-27 |
20210155581 | AROMATIC SUBSTITUTED ETHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS - The disclosure provides recording materials including aromatic substituted ethane-core derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several structures are disclosed for monomers and polymers for use in Bragg gratings applications, leading to materials with higher refractive index, low birefringence, and high transparency. The disclosed derivatized monomers and polymers thereof can be used in any volume Bragg gratings materials, including two-stage polymer materials where a matrix is cured in a first step, and then the volume Bragg grating is written by way of a second curing step of a monomer. | 2021-05-27 |
20210155582 | METHOD AND REACTOR FOR PRODUCING UREA AMMONIUM SULPHATE - The present invention relates to a method for the production of an urea ammonium sulphate (UAS) composition, wherein said UAS composition comprises 1 to 40 weight % of ammonium sulphate (AS) relative to the total weight of the UAS composition, from sulphuric acid, ammonia and/or ammonium carbamate, and urea, in a pipe reactor comprising at least a reactor section wherein feeds of sulphuric acid and/or ammonium bisulphate, ammonia and/or ammonium carbamate, and urea are combined to obtain said urea ammonium sulphate (UAS) composition, comprising the step of including a viscosity-reducing agent, selected from the group of water soluble aluminium salts, into one or more of said feeds. Preferably, said agent is an aluminium sulphate (AluS). The present invention also relates to a pipe reactor for the production of a urea ammonium sulphate (UAS) composition from sulphuric acid, ammonia and/or ammonium carbamate, and urea, the pipe reactor comprising at least a reactor section wherein continuous feeds of sulphuric acid and/or ammonium bisulphate, ammonia and/or ammonium carbamate and urea are combined to obtain said urea ammonium sulphate (UAS) composition, wherein the pipe reactor further comprises means for supplying an aqueous solution of a viscosity-reducing agent to the urea solution upstream of said pipe reactor section, which agent reduces the viscosity of said UAS solution or slurry. The present invention also relates to the use of aluminium sulphate as viscosity-reducing agent in in a method for the production of urea ammonium sulphate (UAS) composition, wherein said UAS composition comprises 1 to 40 weight % of ammonium sulphate (AS) relative to the total weight of the UAS composition, from sulphuric acid, ammonia and/or ammonium carbamate, and urea, in a pipe reactor comprising at least a reactor section wherein continuous feeds of sulphuric acid and/or ammonium bisulphate, ammonia and/or ammonium carbamate and urea are combined to obtain said urea ammonium sulphate (UAS) composition. | 2021-05-27 |
20210155583 | AFFINITY ILLUDOFULVENE CONJUGATES - In an embodiment of the invention, a composition for treating a cell population comprises a medicant. The medicant moiety can be an illudofulvene analog. In an embodiment of the invention, a composition for treating a cell population comprises an Affinity Medicant Conjugate (AMC). The affinity moiety can be an antibody, an antibody fragment, a receptor protein, a peptidic growth factor, an anti-angiogenic protein, a specific binding peptide, protease cleavable peptide, a glycopeptide, a peptide, a peptidic toxin, a protein toxin and an oligonucleotide. The affinity moiety can be covalently bound to the medicant via a linker. | 2021-05-27 |
20210155584 | AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS - The disclosure provides recording materials including aromatic substituted methane-core derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several structures are disclosed for monomers and polymers for use in Bragg gratings applications leading to materials with higher refractive index, low birefringence, and high transparency. The disclosed derivatized monomers and polymers thereof can be used in any volume Bragg gratings materials, including two-stage polymer materials where a matrix is cured in a first step, and then the volume Bragg grating is written by way of a second curing step of a monomer. | 2021-05-27 |
20210155585 | ANTHRAQUINONE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS - The disclosure provides recording materials including anthraquinone derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several structures are disclosed for anthraquinone derivatized monomers and polymers for use in Bragg gratings applications, leading to materials with higher refractive index, low birefringence, and high transparency. The disclosed anthraquinone derivatized monomers and polymers thereof can be used in any volume Bragg gratings materials, including two-stage polymer materials where a matrix is cured in a first step, and then the volume Bragg grating is written by way of a second curing step of a monomer. | 2021-05-27 |
20210155586 | Polymorphs Of 1-(4-Benzyloxy-Benzyl)-3-Methyl-Thiourea - The present disclosure relates to a 1-(4-benzyloxy-benzyl)-3-methyl-thiourea compound in crystalline forms A, B, C, or amorphous form, a method for preparing the compound in the crystalline or amorphous forms, and a use of the compound for preventing or treating a metabolic disease or inflammatory disease. | 2021-05-27 |
20210155587 | Method For Preparing Novel Crystalline Forms Of 1-(4-Benzyloxy-Benzyl)-3-Methyl-Thiourea - The present disclosure relates to a method for preparing 1-(4-benzyloxy-benzyl)-3-methyl-thiourea and a method for preparing a novel stable crystalline form A of 1-(4-benzyloxy-benzyl)-3-methyl-thiourea. | 2021-05-27 |
20210155588 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF - The invention provides compounds having the general formula I: | 2021-05-27 |
20210155589 | METHOD OF PREPARING (3R,4S)-3-ACETAMIDO-4-ALLYL-N-(TERT-BUTYL)PYRROLIDINE-3-CARBOXAMIDE - A method is provided to conveniently separate racemic (3R,4S)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide and (3S,4R)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide using selective crystallization with chiral carboxylic acids. | 2021-05-27 |
20210155590 | ISOINDOLE DERIVATIVE - Disclosed is a compound of formula (I) and a stereoisomer thereof: | 2021-05-27 |
20210155591 | 2-(2,2-DIARYLETHYL)-CYCLIC AMINE DERIVATIVE OR SALT, SYNTHESIS THEREOF, AND APPLICATION AND COMPOSITION THEREOF - The disclosure relates to a 2-(2,2-diarylethyl)-cyclic amine derivative or salt, a synthesis method, an application and a composition thereof. Biological activity test shows that this kind of 2-(2,2-diarylethyl)-cyclic amine derivative has good M-receptor antagonistic activity; and can be used as an active component of drugs for the treatment of the diseases mediated or regulated by muscarinic receptors, such as asthma, chronic obstructive pulmonary disease (COPD), overactive bladder (OAB), bronchospasm with chronic obstructive pulmonary disease, visceral spasm, irritable bowel syndrome, Parkinson's disease, depression or anxiety, schizophrenia and related mental diseases. | 2021-05-27 |
20210155592 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS - The invention provides heterocyclic compounds with quaternary centers and methods of preparing compounds. Methods include the method for the preparation of a compound of Formula (II): | 2021-05-27 |
20210155593 | HDAC INHIBITORS FOR THE TREATMENT OF DIABETIC PERIPHERAL NEUROPATHY - The invention relates to HDAC inhibitors for use in the treatment of diabetic peripheral neuropathy in a subject in need thereof. Also provided herein are methods for treating diabetic peripheral neuropathy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC inhibitor. | 2021-05-27 |
20210155594 | HETEROCYCLIC DERIVATIVES AND USE THEREOF - The present invention relates to novel heterocyclic compounds useful in preparing drugs for the prevention or treatment of diseases associated with STAT3 protein. Specifically, these drugs are useful in the prevention or treatment of solid tumors, blood cancers, radiation or drug-resistant cancers, metastatic cancers, inflammatory diseases, immune system diseases, diabetes, macular degeneration, papillomavirus infections and tuberculosis. | 2021-05-27 |
20210155595 | PROCESS FOR THE PREPARATION OF 1-(2-METHOXYMETHYL-3-METHYLPHENYL)4H-TETRAZOLIN-5-ONE - The invention relates to a process for the preparation of 1-(2-methoxymethyl-3-methylphenyl)4H-tetrazolin-5-one, comprising a step of reacting an isocyanate compound with an azide salt in a solvent and in the presence of a silicon derivative as a catalyst. | 2021-05-27 |
20210155596 | PHARMACEUTICAL COMPOSITION COMPRISING DERIVATIVE COMPOUND OF 1,2-NAPHTHOQUINONE FOR PREVENTING OR TREATING SOLID CANCER OR BLOOD CANCER - The present invention relates to a pharmaceutical composition for preventing or treating solid cancer and blood cancers such as acute leukemia and chronic leukemia, comprising a derivative compound of 1,2-naphthoquinone or a pharmaceutically acceptable salt thereof as an effective component. The derivative compound of 1,2-naphthoquinone is highly effective in killing cancer cells of various solid cancers, acute leukemia, and chronic leukemia, and thus can be beneficially used as a pharmaceutical composition for preventing or treating cancers, especially solid cancers, acute leukemia, and chronic leukemia. | 2021-05-27 |
20210155597 | COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN - The present disclosure relates to compositions comprising a transient receptor potential vanilloid-1 (TRPV1) antagonist and an alpha-2 adrenoreceptor agonist useful in the treatment of various forms of pain, including chronic pain (CP) syndromes, inflammatory pain and pain associated with neuropathy and other diseases and disease states; and methods of use thereof. | 2021-05-27 |
20210155598 | CLASS OF BISQUATERNARY AMMONIUM COMPOUND AS WELL AS THE PREPARATIVE METHOD AND THE USE THEREOF - A two-quaternary ammonium compound has a structural formula of formula (I). L1 is a C1 to C8 alkylene group; L2 is a C1 to C8 alkylene group; Z1 is nitro group or a halogen or methoxy group; Z2 is nitro group or a halogen or methoxy group; Z3 is nitro group or a halogen or methoxy group; R═H or a C1 to C6 alkyl group; a, b, and c are independently an integer from 0-5; and M is a pharmaceutically acceptable anion, such as a bromine ion, chlorine ion, sulfonate radical, etc. A stereoisomer or mixture of stereoisomers, or a pharmaceutically acceptable salt or solvate or eutectic of the compound of formula (I) forms a composition with a pharmaceutically acceptable carrier, or forms a compounded prescription with other active components, and the composition or compounded prescription may be used in the preparation of a muscle relaxant. | 2021-05-27 |
20210155599 | AROMATIC SUBSTITUTED ALKANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS - The disclosure provides recording materials including aromatic substituted alkane-core derivatized monomers and polymers for use in volume Bragg gratings, including, but not limited to, volume Bragg gratings for holography applications. Several structures are disclosed, including Formula I. When used in Bragg gratings applications, the monomers and polymers disclosed lead to materials with higher refractive index, low birefringence, and high transparency. The disclosed derivatized monomers and polymers can be used in any volume Bragg gratings materials, including two-stage polymer materials where a matrix is cured in a first step, and then the volume Bragg grating is written by way of a second curing step of a monomer. | 2021-05-27 |
20210155600 | Urea-Oxaziridines - Chemoselective conjugation is achieved through redox reactivity by reacting an N-transfer oxidant with a thioether substrate in a redox reaction in an aqueous environment to form a conjugation product. In embodiments, Redox-Activated Chemical Tagging (ReACT) strategies for methionine-based protein functionalization. Oxaziridine (Ox) compounds serve as oxidant-mediated reagents for direct functionalization by converting methionine to the corresponding sulfimide conjugation product. | 2021-05-27 |
20210155601 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) - The present invention provides compounds that are dual inhibitors of soluble epoxide hydrolase and fatty acid amide hydrolase. The present invention also provides methods of using the compounds to inhibit soluble epoxide hydrolase and fatty acid amide hydrolase, and to treat cancer. | 2021-05-27 |
20210155602 | TETRAHYDROQUINOLINO DERIVATIVES FOR THE TREATMENT OF METASTATIC AND CHEMORESISTANT CANCERS - Disclosed herein are compounds of Structural Formula I. Compounds of Structural Formula I inhibit aldehyde dehydrogenase isoform Ia3 (ALDHIa3) and arc useful for treating cancer, for example, metastatic or chemoresistant cancer, such as metastatic cancer resistant to chemotherapy. Also disclosed herein are compositions comprising compounds of Structural Formula I and uses of compounds of Structural Formula I for treating cancer, for example, metastatic or chemoresistant cancer. | 2021-05-27 |
20210155603 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE - Provided are compounds useful for treating of cancer and methods for treating of cancer, comprising administering to a subject in need thereof a compound described therein. | 2021-05-27 |
20210155604 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF - Related to a quinazoline compound serving as an EFGR triple mutation inhibitor and applications thereof. Specifically, disclosed are a compound as represented by the following formula (I), a pharmaceutical composition comprising the compound of formula (I), and applications of the compound in treating a related disease mediated by EGFR and in a medicament for treating the related disease mediated by EGFR. | 2021-05-27 |
20210155605 | SALTS OF A PIM KINASE INHIBITOR - The present invention relates to salt forms of the Pim kinase inhibitor N-{(7R)-4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-3-yl}-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide, including methods of preparation thereof, and intermediates in the preparation thereof, where the compound is useful in the treatment of Pim kinase-related diseases such as cancer. | 2021-05-27 |
20210155606 | AMINOPYRIDINE DERIVATIVES AND THEIR USE AS SELECTIVE ALK-2 INHIBITORS - The invention relates to a compound of formula (1) in free form or in pharmaceutically acceptable salt form | 2021-05-27 |
20210155607 | INTERMEDIATES USEFUL FOR THE SYNTHESIS OF A SELECTIVE INHIBITOR AGAINST PROTEIN KINASE AND PROCESSES FOR PREPARING THE SAME - The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same. | 2021-05-27 |
20210155608 | HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES - The present invention relates to novel heteroaryl-triazole and heteroaryl-tetrazole compounds of the general formula (I), in which the structural elements Y, Q | 2021-05-27 |
20210155609 | PYRAZOLYLACYLPYRAZOLINE COMPOUNDS AND METHOD FOR TREATING PAIN - This invention relates to pyrazolylacylpyrazoline compounds or pharmaceutically acceptable salts thereof, and for the use of the compounds to treat neurological disorders. | 2021-05-27 |
20210155610 | Iridinesulfonamide Compound And Use Method Thereof - An iridinesulfonamide compound having isocitrate dehydrogenase 1 (IDH1) inhibitory activity, pharmaceutically acceptable salts, solvates or hydrates thereof, a pharmaceutical composition, as well as use of the compound or the pharmaceutically acceptable salts, solvates or hydrates thereof, and the pharmaceutical composition thereof in treating IDH1 mutation induced cancer. | 2021-05-27 |
20210155611 | THE SALTS OF A COMPOUND AND THE CRYSTALLINE FORMS THEREOF - The present invention belongs to the pharmaceutical field, and provides the compound 4-ethyl-N-(4-((3-ethynyiphenypamino)-7-methoxyquinazolin-6-yDpiperazine-1-carboxamide succinate and the crystalline forms thereof, the solvates and the crystalline forms thereof, the pharmaceutical compositions comprising the same as well as the methods of preparing the same and the use thereof. | 2021-05-27 |
20210155612 | Alpha,Beta-UNSATURATED AMIDE COMPOUND - An object of the present invention is to provide an α,β-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like. The α,β-unsaturated amide compound represented by the following formula (I) or a pharmaceutically acceptable salt or the like thereof has anticancer activity and the like: | 2021-05-27 |
20210155613 | FRUQUINTINIB EUTECTIC CRYSTAL, PREPARATION METHOD THEREFOR, COMPOSITION, AND USES THEREOF - Provided are a fruquintinib and a saccharin salt or eutectic crystal, a fruqintinib and a malonic acid eutectic crystal or a fruquintinib and a maleic euctectic crystal, a preparation method therefor, a pharmaceutical composition containing thereof, and uses thereof in preparing drugs for treating and/or preventing diseases related to abnormal angiogenesis, such as cancer, tumors, macular degeneration, chronic inflammation and the like. | 2021-05-27 |
20210155615 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION - Compounds of formula (I) wherein, R | 2021-05-27 |
20210155616 | SYNTHESIS OF DISORAZOLES AND ANALOGS THEREOF AS POTENT ANTICANCER AGENTS - In one aspect, the present disclosure provides disorazole analogs of the formula: Formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided. | 2021-05-27 |
20210155617 | INHIBITORS OF TYPE l METHIONYL-TRNA SYNTHETASE AND METHODS OF USING THEM - The present disclosure is generally directed to compositions useful in the inhibition of MetRS and methods for treating diseases that are ameliorated by the inhibition of MetRS. | 2021-05-27 |
20210155618 | SPIROHEPTANYL HYDANTOINS AS ROCK INHIBITORS - The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same. | 2021-05-27 |
20210155619 | MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES - Intermediates for compounds of the formula (I): | 2021-05-27 |
20210155620 | DIMETHYL AMINO AZETIDINE AMIDES AS JAK INHIBITORS - The invention provides compounds of formula (I): | 2021-05-27 |
20210155621 | [1,2,4]TRIAZOLO[1,5-A]PYRIDINE COMPOUND AS JAK INHIBITOR AND USE THEREOF - Disclosed are a [1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and an application thereof in preparing a drug for treating a disease related to JAK or/and TYK2. Specifically, the present invention relates to a compound represented by formula (I), or an isomer or pharmaceutically acceptable salt thereof. (I) | 2021-05-27 |