23rd week of 2018 patent applcation highlights part 22 |
Patent application number | Title | Published |
20180155197 | Apparatus and Method for Generating Nitric Oxide in Controlled and Accurate Amounts - A nitric oxide generator generates nitric oxide from a mixture of nitrogen and oxygen such as air treated by a pulsating electrical discharge. The desired concentration of nitric oxide is obtained by controlling at least one of a frequency of the pulsating electrical discharge and duration of each electrical discharge pulse. | 2018-06-07 |
20180155198 | SOLID ELECTROLYTE PRODUCTION METHOD - The invention provides a method for producing a solid electrolyte, which includes reacting two or more kinds of solid raw materials using a multi-axial kneading machine to give an amorphous solid electrolyte, and which can provide amorphous and crystalline solid electrolytes with excellent productivity and mass-productivity, as well as a method for producing a crystalline solid electrolyte including producing the amorphous solid electrolyte followed by heating the solid electrolyte. | 2018-06-07 |
20180155199 | Novel Carbon Allotrope: Protomene - The present invention provides a new and useful synthetic carbon allotrope which contains multiple clusters of carbon atoms dispersed throughout the carbon allotrope. These clusters contain carbon atoms which are bonded to four other carbon atoms by sp2 hybridized bonds. The allotrope further contains multiple surrounding carbon atoms, which are bonded to each other by sp3 hybridized bonds. One of the multiple clusters of carbon atoms is centrally located within the carbon allotrope. | 2018-06-07 |
20180155200 | FERROCENE CATALYZED METHOD FOR PREPARING CARBON NANOTUBES - A method for preparing multi-wall carbon nanotubes comprising atomizing a precursor solution comprising an aromatic hydrocarbon and a carrier gas. The mixture is then injected through an ultrasonic atomization system to form atomized precursor droplets. Then by injecting the atomized precursor droplets from the top of a vertical chemical vapor deposition reactor, the droplets can then react with a reaction gas in the reactor vessel to form a film that adsorbs to a growth surface in the reactor vessel. Layer by layer multi-wall carbon nanotubes are formed. This method is repeated to form layers of the multi-wall carbon nanotubes. The nanotubes formed have an outer diameter of 10 nm-51 nm and a length to diameter aspect ratio of 7200-13200. | 2018-06-07 |
20180155201 | METHOD FOR PREPARING GRAPHENE USING COAL AS RAW MATERIAL - The present disclosure relates to a method for the preparation of graphene from coal as a raw material, and more particularly to a method for the preparation of microporous graphene from Chinese Zhundong coal. The process consists of the following steps: first, refining the coal block or coal particle to get fine powdered coal; second, immersing the powdered coal with activation agent solution and drying water to get molten mixture; third, carbonizing the molten mixture in an inert atmosphere and at a high temperature to obtain the carbonized product; fourth, successively acid washing, water-washing and drying the carbonized product to obtain the coal-based porous graphene with the surface area up to 3345 m | 2018-06-07 |
20180155202 | METHODS FOR CARBON DIOXIDE PRODUCTION AND POWER GENERATION - A method of integrating energy into a power cycle during production of carbon dioxide using the steps of a) combusting a fuel and oxygen in a reactor to produce a mixture of carbon dioxide and water, and form a heat of reaction; b) capturing the heat of reaction; c) converting the heat of reaction into electrical energy; d) feeding the electrical energy into the power cycle; and e) purifying and recovering carbon dioxide. Alternatively, a method for the production of carbon dioxide and power is disclosed by a) combusting a fuel and oxygen in a reactor to produce a flue gas comprising carbon dioxide and contaminants and a heat of reaction; b) recovering heat from the reactor and producing electricity from the heat; c) integrating the electricity into a power cycle; and d) removing contaminants from the carbon dioxide and recovering purified carbon dioxide. | 2018-06-07 |
20180155203 | POLYALUMINUM SALTS AND THEIR USES IN PREPARATION OF HIGH-PURITY COLLOIDAL ALUMINUM-SILICA COMPOSITE PARTICLES AND ZEOLITES - Disclosed are novel aqueous aluminum complex compositions and methods of making and using them. The novel compositions comprise very low halide content, even when made from aluminum chlorohydrate. The compositions find use in the production of zeolites, coatings, abrasives, binders, and refractories; and in the treatment of wastewater for example. The methods of making the novel compositions include passing a first aqueous aluminum complex composition through an anion exchange column or otherwise contacting the first composition with the anion exchange resin to provide a second aqueous aluminum complex composition that is different from the first aqueous aluminum complex composition. Also disclosed are methods of making zeolites and aqueous silica-alumina compositions from the novel aqueous aluminum complex compositions. | 2018-06-07 |
20180155204 | PROCESS FOR THE PREPARATION OF SODIUM CYANIDE - The invention relates to a process for the preparation of alkali metal cyanides as a solid substance, comprising the steps of: i) an absorption step in the form of an absorption of hydrogen cyanide from a hydrogen cyanide-containing synthesis gas in an aqueous alkali metal hydroxide solution; ii) a crystallization step in the form of introducing said alkali metal cyanide solution into an evaporative crystallizer; iii) a separation step; iv) a recycle step; v) a drying step. | 2018-06-07 |
20180155205 | EFFICIENT METHOD FOR DECONTAMINATING WASTE GASES AND WASTE WATER CONTAINING CYANIDE IN A METHOD FOR PRODUCING ALKALI METAL CYANIDES - The invention relates to a method for producing alkali metal cyanides as solids, comprising the steps: i) an absorption step in the form of the absorption of hydrogen cyanide from a syngas containing hydrogen cyanide in an aqueous alkali metal hydroxide solution; ii) a preparation step for the waste gases containing cyanide that have accumulated in step i); iii) a crystallization step in the form of the introduction of the alkali metal cyanide solution into an evaporative crystallizer; iv) a condensation step for the vapour containing cyanide that has accumulated in step iii) to obtain a vapour condensate containing cyanide; v) a recirculation step, in which the vapour condensate containing cyanide that has been obtained in step iv) is used as an aqueous liquid in step ii). | 2018-06-07 |
20180155206 | METHOD OF PRODUCING HIGH-PURITY NANO ALUMINA - A method of producing a high-purity nano alumina powder, in which general aluminum hydroxide is dissolved in a sodium hydroxide solution to give a sodium aluminate solution, most insoluble impurities other than sodium are removed using a micro filter to give a pure sodium aluminate solution. A seed is added thereto so as to precipitate nano aluminum hydroxide as a nano slurry under optimal precipitation conditions. The nano aluminum hydroxide slurry is filtered, dried, disintegrated, and then calcined at a low temperature of 900° C. or less, thus achieving the mass production of high-purity nano alumina having a particle size of 200 nm or less, whereby high-purity alumina nanoparticles can be produced in an environmentally friendly manner at low cost. | 2018-06-07 |
20180155207 | Process For Preparing Calcium Fluoride From Fluosilicic Acid - The invention relates to a process for preparing synthetic calcium fluoride (CaF | 2018-06-07 |
20180155208 | PROCESSING OF COBALTOUS SULPHA/DITHIONATE LIQUORS DERIVED FROM COBALT RESOURCE - A process for water removal and/or recycling of sodium sulfate and/or sodium dithionate containing liquors derived from processing cobalt resource material essentially free of lithium comprising the steps of precipitation of cobalt as cobaltous carbonate or cobaltous hydroxide followed by removal thereof from the liquor, crystallization of sodium sulfate and sodium dithionate and removal of the crystals, followed by heating of the crystals to anhydrous sodium sulfate, sulphur dioxide and water and then separating the anhydrous sodium sulfate. | 2018-06-07 |
20180155209 | WATER PURIFICATION DEVICE - This invention concerns a fluid purification device. The device has container, a nozzle and a removable filter element. The container is preferably a bottle and has at least partially flexible sidewalls so that it is collapsible from a first, operative condition into a second, inoperative condition. The nozzle is connectable to the container and defines a first fluid flow path along which fluid flows when, in use, filling the container and a second fluid flow path along which fluid flows when, in use, dispensing fluid from the container. The removable filter element is carried by the nozzle such that it is positioned in the first fluid flow path so that the fluid is filtered when filling the container and positioned outside the second fluid flow path so that the flow of fluid is unobstructed by it when dispensing fluid from the container. The invention also concerns a method of filtering a fluid. | 2018-06-07 |
20180155210 | SOLAR DESALINATION SYSTEM EMPLOYING A HUMIDIFICATION-DEHUMIDIFICATION PROCESS - A hydro-thermal exchange unit (HTEU) for desalinating feed water in accordance with a humidification-dehumidification includes feed water, fresh water and gas conduit circuits for transporting feed water, fresh water, and gas, respectively. The unit also includes an evaporator through which a portion of the feed water conduit and the gas conduit pass. The evaporator causes evaporation of a portion of the feed water to produce vapor that is transported through the gas conduit. The unit also includes a condenser through which a portion of the gas conduit and the fresh water conduit pass. The condenser has input and output ports for coupling the gas and fresh water conduit circuits. The condenser extracts moisture from the vapor transported therethrough by the gas conduit. The extracted moisture is discharged through the fresh water conduit. The unit also includes a heat exchanger through which a portion of the fresh water conduit and the feed water conduit pass to thereby extract residual heat from the fresh water such that the residual heat heats the feed water. | 2018-06-07 |
20180155211 | SYSTEMS AND METHODS OF PROVIDING MICRO-RENEWABLE ELECTRICAL ENERGY - Various implementations of a system that addresses the need for clean drinking water, improved solid fuel combustion and convection of the heat resulting from the combustion, exhausting of gases and air-borne particulates resulting from combustion, and provides electricity for lighting and charging of battery-operated devices are described herein. The system may include at least one solar panel, a battery, a fan assisted exhaust hood, a fan assisted cooking device, and a water purification device. Such a device could not only save millions of lives, but the quality of life for millions of people living in impoverished areas or refugee camps could be improved dramatically. | 2018-06-07 |
20180155212 | SYSTEMS AND METHODS OF PROVIDING MICRO-RENEWABLE ELECTRICAL ENERGY - Various implementations of a system that addresses the need for clean drinking water, improved solid fuel combustion and convection of the heat resulting from the combustion, exhausting of gases and air-borne particulates resulting from combustion, and provides electricity for lighting and charging of battery-operated devices are described herein. The system may include at least one solar panel, a battery, a fan assisted exhaust hood, a fan assisted cooking device, and a water purification device. Such a device could not only save millions of lives, but the quality of life for millions of people living in impoverished areas or refugee camps could be improved dramatically. | 2018-06-07 |
20180155213 | Process For Purification Of Contaminated Water - The present disclosure relates to water purification. The teachings thereof may be embodied in processes for removing contaminants from contaminated water. An example process may include: boiling or evaporating a contaminated water to distill the contaminated water; removing a vapor stream from the boiling or evaporating contaminated water; delivering the vapor stream to an oxidation unit; removing additional contaminants from the vapor stream in the oxidation unit; and discharging a purified water stream from the oxidation unit. | 2018-06-07 |
20180155214 | COMPOSITIONS AND METHODS FOR THE REMOVAL OF PHOSPHATES AND OTHER CONTAMINANTS FROM AQUEOUS SOLUTIONS - Compositions and methods for removing phosphates, nitrates and heavy metals from aqueous solutions. | 2018-06-07 |
20180155215 | STERILIZATION DEVICE - A sterilization device includes: a processing chamber in which a fluid passing through a straightener flows in a first direction, the straightener being provided at an inlet of the processing chamber; a plurality of light emitting devices arranged in an array on a plane facing the straightener in the first direction, sandwiching the processing chamber, and irradiating the fluid in the processing chamber with ultraviolet light; a light source chamber that houses the plurality of light emitting devices inside; and a discharge path provided to the side of the light source chamber and allowing the fluid passing through the processing chamber to flow in the first direction. | 2018-06-07 |
20180155216 | Skimmer and oil water separator process - A skimmer for removing a layer of oil floating on a surface oil contaminated water which subsequently concentrated and separated in an oil water separator which removes tramp oils or other fluids, such as hydraulic oils, with specific gravity less than that of the operating fluid are required to be removed from operating fluid such as water, lubri-coolants or other liquids. The skimmer supplies concentrated oil water composite fluid to a separator apparatus designed for use in industrial applications in which unwanted tramp oils or other fluids, such as hydraulic oils, with specific gravity less than that of the operating fluid are required to be removed from operating fluid such as water, lubri-coolants or other liquids. | 2018-06-07 |
20180155217 | SYSTEM, DEVICE AND METHOD FOR THE REMOVAL OF FOULING PRECIPITATES FROM FILTRATION MEMBRANES - There is provided a system for the removal of scaling precipitants obtained due to dewatering a solution including i. at least one membrane, such as FO membrane adapted to be at least partially surrounded by a feed solution and to receive a flow through of a draw solution; and ii. a device adapted to control the flow of said draw solution through said at least one membrane; wherein said system is configured to operate in at least three predetermined different modes of operation including; filtration mode, osmotic relaxation mode and pulsation mode, according to some demonstrative embodiments. | 2018-06-07 |
20180155218 | OSMOTIC SEPARATION SYSTEMS AND METHODS - Separation processes using osmotically driven membrane systems are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane. | 2018-06-07 |
20180155219 | ELECTROCOAGULATION FLUID TREATMENT SYSTEM - A fluid treatment system having an electrocoagulation unit for treating fluid. In one embodiment, the electrocoagulation unit is has a cathode with an electrically conductive cathode tube surrounding a reactor cell. The reactor cell is provided with a non-electrically conductive reactor shell having a plurality of perforations, a plurality of reactor beads disposed within the reactor shell, and an anode rod disposed within the reactor shell in direct contact with at least a portion of some of the reactor beads. When an electrical current is applied to the anode rod and the cathode tube, an electric gradient is created between the anode rod and the cathode tube ionizing contaminants in a fluid passed from the fluid inlet to the fluid outlet. | 2018-06-07 |
20180155220 | System and Method for Treating Water Systems with High Voltage Discharge and Ozone - A system and method for treating flowing water systems with a plasma discharge to remove or control growth of microbiological species. Components of the water system are protected from being damaged by excess energy from the electrohydraulic treatment. Ozone gas generated by a high voltage generator that powers the plasma discharge is recycled to further treat the water. A gas infusion system may be used to create fine bubbles of ozone, air, or other gases in the water being treated to aid in plasma generation, particularly when the conductivity of the water is high. An electrode mounting assembly maintains a high voltage electrode and ground electrode at a fixed distance from each other to optimize plasma generation. An open support structure for the high voltage generator circuit physically separates spark gap electrodes and resists metal deposits that may disrupt discharge of a high voltage pulse to create the plasma. | 2018-06-07 |
20180155221 | WATER TREATMENT SYSTEM AND METHODS USING RADIAL DEIONIZATION - Apparatuses, systems, and methods for treating cooling tower water with a radial deionization unit are disclosed. The radial deionization unit may alone or in conjunction with other treatment units treat a make-up water being fed to a cooling tower, in order to remove dissolved solids from the water. The radial deionization unit may, in some cases, receive reclaimed water from the cooling tower or other unit operations | 2018-06-07 |
20180155222 | Systems And Processes For Treating Textiles With An Antimicrobial Agent - According to an aspect of the present disclosure, a method of treating a textile with an antimicrobial agent over a plurality of laundry cycles each including a wash cycle and a treatment cycle. The method includes (a) receiving a textile in a wash system for a first laundry cycle, (b) initiating a wash cycle comprising a detergent, (c) initiating a post-detergent treatment cycle comprising dosing the textile with a solution having a predetermined concentration of an antimicrobial agent that comprises a metallic ion, and (c) repeating steps (a)-(c) for each of a plurality of additional laundry cycles. The predetermined concentration is insufficient to achieve a predetermined antimicrobial efficacy for the textile due to the first laundry cycle alone but sufficient to achieve the predetermined antimicrobial efficacy for the textile due to a combination of the first laundry cycle and one or more of the plurality of additional laundry cycles. | 2018-06-07 |
20180155223 | SELF-CIRCULATING FLOCCULATION WASHING MACHINE AND CONTROL METHOD - A self-circulating flocculation washing machine comprises an outer barrel, a clothes washing structure arranged in the outer barrel and a flocculation water treatment device arranged outside the outer barrel, and the flocculation water treatment device comprises a flocculation container for performing flocculation treatment on water drained from the outer barrel; the washing machine is also provided with a circulating pipe for driving washing water in the outer barrel to perform self-circulation from bottom to top; one end of the circulating pipe communicates with a self-circulating water outlet in the lower part of the outer barrel, the other end of the circulating pipe communicates with a water outlet of the flocculation container and a self-circulating water inlet of the outer barrel through a tee joint, and a non-return structure for preventing the flocculation water from reflowing is arranged between the tee joint and the water outlet of the flocculation container. | 2018-06-07 |
20180155224 | METHOD OF TREATING WASTEWATER - Provided is a method of treating wastewater, which can treat wastewater, particularly organic wastewater while saving labor and decreasing the environmental impact by improving deterioration in the purification performance due to clogging of the filter bed, which is regarded as a problem when purifying wastewater, particularly organic wastewater having high SS concentration, BOD, and COD by a constructed wetland and by decreasing increases in the area and the number of stages of wetland required due to an increase in the BOD and COD load. A method of treating wastewater provided comprises: an aggregate floc forming step of forming an aggregate floc by adding a polymer flocculant to wastewater; a solid-liquid separation step of obtaining separated water by solid-liquid separation of the aggregate floc; and a purification step of purifying the separated water by using a constructed wetland. | 2018-06-07 |
20180155226 | Multiple Uses of Amine Salts for Industrial Water Treatment - A method for treating in an industrial water treatment system for at least two of metal corrosion inhibition, scale inhibition, suspended matter dispersion, biocide efficacy, or biofilm removal/biofilm dispersion is taught by the use of at least one compound which is a salt derived from a thioamine or an oxyamine and an acid. | 2018-06-07 |
20180155227 | BIOREFINERY METHOD AND SYSTEM FOR ISOLATED ENVIRONMENTS - A Biorefinery System (BIOSYS) that effectively treats all human activity-derived waste (black water, grey water, and food waste streams) using biological systems and that produces as process by-products: recovered potable water, liberated free oxygen, edible protein cake (with and without lipids), soil amendments, and machinery lube oils. Additionally, the system captures and chemically binds carbon dioxide into microbial cells and associated by-products, thus producing recovered usable returned cabin air. | 2018-06-07 |
20180155228 | METHOD AND DEVICE FOR PURIFYING DOMESTIC OR INDUSTRIAL WATER - A method and a device for the continuous purification of a domestic or industrial water stream. After passing through a biological reactor to obtain a sludge of between 4 and 12 g/l of Dry Solids, the method involves feeding a series of chambers separated by restrictions at a flow rate q, injecting air into a second chamber at a flow rate Q>q, in order to obtain an emulsion, injecting a flocculant into a third chamber, and recovering the degassed emulsion in a drain pan. Flocculated and aerated sludge floats on top, such that the remaining liquid centrate has a Dry Solids content less than 100 mg/l and has a positive redox potential>50 mV and a value greater than 100 mV relative to the redox potential of the sludge at the inlet of the chambers, and is reinjected upstream from or into the biological reactor. | 2018-06-07 |
20180155231 | FLOW STOPPER FOR A BOTTOM DELIVERY MELTER - An apparatus for stopping flow from a bottom delivery orifice of a melter includes a plug having a barrel terminating in a tapered nose. The tapered nose occludes the bottom delivery orifice when inserted a sufficient distance into the bottom delivery orifice. The plug is provided with internal cooling. One or more spray tubings are provided externally to the plug to reduce the temperature of any molten material leaking from the bottom delivery orifice while inserting the tapered nose into the bottom delivery orifice. | 2018-06-07 |
20180155232 | METHOD AND APPARATUS FOR SHAPING GLASS SHEETS - The invention relates to a method for shaping a glass sheet comprising the steps (i) heating the glass sheet to a temperature suitable for shaping; (ii) depositing the glass sheet on a first bending tool for supporting the glass sheet thereon, the glass sheet being in a first position relative to the first bending tool; (iii) contacting an edge portion of the glass sheet such that the glass sheet is moved to a second position relative to the first bending tool; and (iv) shaping the glass sheet on the first bending tool. Positioning devices for moving a hot glass sheet during the method of the invention are described. A glass shaping line for carrying out the method is also described. | 2018-06-07 |
20180155234 | LITHIUM DISILICATE GLASS-CERAMIC, METHOD FOR PRODUCTION THEREOF AND USE THEREOF - The invention relates to glass-ceramics based on the lithium disilicate system which can be mechanically machined easily in an intermediate step of crystallisation and, after complete crystallisation, represent a very strong, highly-translucent and chemically-stable glass-ceramic. Likewise, the invention relates to a method for the production of these glass-ceramics. The glass-ceramics according to the invention are used as dental material. | 2018-06-07 |
20180155235 | HIGH STRENGTH, SCRATCH RESISTANT AND TRANSPARENT GLASS-BASED MATERIALS - Embodiments of a transparent glass-based material comprising a glass phase and a second phase that is different from and is dispersed in the glass phase are provided. The second phase may comprise a crystalline or a nanocrystalline phase, a fiber, and/or glass particles. In some embodiments, the second phase is crystalline. In one or more embodiments, the glass-based material has a transmittance of at least about 88% over a visible spectrum ranging from about 400 nm to about 700 nm and a fracture toughness of at least about 0.9 MPa·m | 2018-06-07 |
20180155236 | LIGHT-SCATTERING GLASS ARTICLES AND METHODS FOR THE PRODUCTION THEREOF - According to embodiments disclosed herein, light-scattering laminated glass articles may include a first glass layer, a second glass layer, and a light-scattering component. The first glass layer may be formed from a first glass composition. The second glass layer may be formed from a second glass composition and fused to the first glass layer. The light-scattering component may be disposed at an interface of the first glass layer and the second glass layer. The light-scattering component may include a different composition or material phase than the first glass layer and the second glass layer. Also disclosed herein are methods for producing light-scattering laminated glass articles. | 2018-06-07 |
20180155237 | METHOD FOR MANUFACTURING SUBSTRATE - A method for manufacturing a substrate is disclosed. The method comprises the following steps: step one, depositing an amorphous silicon layer on a base material; step two, depositing a silicon dioxide layer with a first thickness on the amorphous silicon layer; and step three, etching the silicon dioxide layer until a thickness thereof is reduced to a second thickness. According to the method of the present disclosure, the silicon dioxide layer with a needed thickness can be manufactured on the amorphous silicon layer. When the ELA procedure is performed, the silicon dioxide layer has an enough thickness to prevent the formation of protrusions at grain boundary of polysilicon, so that the semi-conductive layer manufactured therein can have a relatively low roughness. | 2018-06-07 |
20180155238 | FLEXIBLE GLASS ARTICLE HAVING A LOW BENDING CURVATURE AND METHOD OF MAKING THE SAME - Flexible glass articles having modified bending radii and methods of making same provide an ultra-low bending curvature, while still retaining a thin profile and other favorable characteristics of glass. | 2018-06-07 |
20180155239 | SWITCHABLE LIQUID REPELLENT AND ACTIVE WATER HARVESTING SURFACE - A substrate with a switchable surface has been developed that can rapidly switch its surface character such as between two distinct liquid-repellent modes: (1) a superhydrophobic mode and (2) a slippery mode. Such surfaces have demonstrated adaptive liquid repellency and water harvesting capabilities. | 2018-06-07 |
20180155240 | Process for Manufacturing Highly Porous Slaked Lime and Product Thereby Obtained - Process for manufacturing highly porous slake lime comprising a feeding step of quicklime, a feeding step of water in a feeding zone of a hydrator, a slaking step of said quicklime in a slaking zone of said hydrator and a maturation step in a maturation zone of said hydrator to form slaked lime. | 2018-06-07 |
20180155242 | LIGHTWEIGHT FINE CERAMIC PARTICULATES - The present invention relates to lightweight fine ceramic particulates, directly obtained from fly ash, their use in different technical fields and building material compositions comprising the same. | 2018-06-07 |
20180155243 | STABILISATION OF MINERAL FOAMS - The invention relates to a mineral foam stabilised by an association of surfactants comprising: a first surfactant carrying at least one sulfate group; and a second amphoteric surfactant. | 2018-06-07 |
20180155244 | Preparation Method of Polycarboxylate Superplasticizer with Carbon Dioxide - The present invention discloses a preparation method of a polycarboxylate superplasticizer with carbon dioxide, comprising the following steps: (1) preparing a polycarboxylate superplasticizer prepolymer: performing an oxidation-reduction radical polymerization of an unsaturated macromonomer, an unsaturated phenol derivative, a reducing agent, an initiator and a chain transfer agent with different proportions under a nitrogen atmosphere to obtain a novel polycarboxylate superplasticizer prepolymer with different molecular weight; adjusting the pH by adding an alkali; (2) preparing a polycarboxylate superplasticizer: performing a Koble-Schmitt reaction between the polycarboxylate superplasticizer prepolymer and a carbon dioxide for a certain time to obtain the polycarboxylate superplasticizer. The polycarboxylate superplasticizer prepared by the method of the present invention retains the advantages of the existing water-reducing admixture of the polyether monomer compounds, and the production process is simple, safe, controllable, less side effect and has a better cost effective and competitive advantage. | 2018-06-07 |
20180155245 | High Pressure Laminate and Production Method Thereof - The present invention discloses a decorative High Pressure Laminate (HPL) and production method thereof, which relates to the technical field of building decoration materials. The raw materials of HPL may include magnesium oxide, magnesium sulfate, water, fiber, perlite, glass fabric, quartz powder and modifier, wherein the percentage by weight of magnesium oxide is 35% to 40%, the percentage by weight of magnesium sulfate is 20% to 25%, the percentage by weight of water is 20% to 25%, the percentage by weight of fibers is 5% to 10%, the percentage by weight of perlites is 0.5% to 0.9%, the percentage by weight of glass fabrics is 1% to 2%, the percentage by weight of quartz powder is 8% to 12%, and the percentage by weight of modifier is 0.1% to 0.5%. According to the technical solutions, the disclosed HPL may include magnesium oxide, magnesium sulfate, water, fiber, perlite, glass fabric, quartz powder and modifier according to appropriate proportions, and the product produced has low hygroscopicity, no helogenation, no rust, no discoloration, and has high anti-demolition force; moreover, magnesium sulfate has no corrosion on the glass fabric, thus, the laminate has a long life. | 2018-06-07 |
20180155246 | INSULATED CONCRETE FORMS, INSULATING CEMENT, AND RELATED ARTICLES PRODUCED THEREFROM - Various cement-containing compositions are disclosed, including insulating cement, forms, and prefabricated building materials produced from cement-containing compositions with insulating properties. Some of the preferred embodiments include expanded polystyrene and an acrylic component to provide enhanced insulating properties, or have a lower density, lighter weight, and increased insulating R-value in comparison with other cement-containing compositions. | 2018-06-07 |
20180155247 | TRANSPARENT CERAMIC AS A COMPONENT FOR FRACTURE-RESISTANT OPTICAL UNITS - The present invention relates to parts of transparent corundum ceramics and the production and use of said parts. | 2018-06-07 |
20180155248 | COMPOSITE MATERIALS, METHODS OF PRODUCTION AND USES THEREOF - The invention provides novel articles of composite materials having hollow interior channels or passageways, or otherwise being hollowed out, and formulations and methods for their manufacture and uses. These hollow core objects are suitable for a variety of applications in construction, pavements and landscaping, and infrastructure. | 2018-06-07 |
20180155249 | Dielectric Composition, Dielectric Element, Electronic Component and Laminated Electronic Component - The present invention relates to a dielectric composition having a main component and an auxiliary component. The main component is represented by (Bi | 2018-06-07 |
20180155250 | METHOD OF MAKING AN ALUMINA-SILICATE OXYNITRIDE AND CUBIC BORON NITRIDE CERAMIC COMPOSITE - A method for producing a composite of cubic boron nitride dispersed in a SiAlON ceramic. This method involves mixing silicon nitride nanoparticles, aluminum nitride nanoparticles, silica nanoparticles, calcium oxide nanoparticles, and cubic boron nitride microparticles to produce a mixture. The cubic boron nitride may be coated with nickel. The mixture is sintered to produce the composite, and this sintering may involve spark plasma sintering and/or sintering at a relatively low temperature. The composite may comprise a mixture of Ca-α-SiAlON and β-SiAlON ceramic reinforced by boron nitride in either or both cubic and hexagonal phases. | 2018-06-07 |
20180155251 | PRE-FORM BONDING AGENT FOR MAKING VITRIFIED PRODUCTS - Pre-form bonding agent for making vitrified products, said agent including sugar. | 2018-06-07 |
20180155252 | SYSTEMS AND METHODS FOR CERAMIC MATRIX COMPOSITES - Methods for fabricating a ceramic matrix composite are disclosed. A fiber preform may be placed in a mold. An aqueous solution may be added to the fiber preform. The aqueous solution may include water, carbon nanotubes, and a binder. The preform may be frozen. Freezing the preform may cause the water to expand and separate fibers in the fiber preform. The carbon nanotubes may bond to the fibers. The preform may be freeze dried to remove the water. The preform may then be processed according to standard CMC process. | 2018-06-07 |
20180155253 | Passive Digestion - This invention is a method for the processing of organic materials or organic wastes in a cost-effective and environmentally sound manner. The invention works both in the anaerobic or aerobic state. Processing organic material is accomplished by forcing the flow of gas through a pile of material, containing some organic matter, with liquids and gravity. The movement of gas and liquids through the pile results in very large increases in microorganism populations, accelerated evolution of the microorganisms, and corresponding increases in the processing provided organic materials. | 2018-06-07 |
20180155254 | METHOD FOR OLIGOMERIZATION OF OLEFINS (AMENDED) - The present disclosure relates to a method for oligomerization of olefins. The method for oligomerization of olefins according to the present disclosure not only provides excellent catalytic activity and stable process operation, but also exhibits high selectivity to 1-hexene or 1-octene by using a catalyst system including an activity modifier. | 2018-06-07 |
20180155255 | Process of Producing Paraxylene by The Methylation of Toluene and/or Benzene - A process for producing paraxylene by the catalytic alkylation of benzene and/or toluene with methanol. In prior art processes, water is typically co-injected with the methanol to improve the utilization of methanol, increase the amount of methanol that reacts with the benzene and/or toluene, and decrease the amount of methanol that decomposes to undesirable carbon monoxide, carbon dioxide, or water or reacts with itself to produce unwanted light olefinic gases. Rather than using purified methanol and co-feeding water as is taught in the prior art, crude, or unpurified, methanol that contains at least 5 wt %, such as between 5 and 35 wt %, water, based on the total amount of water and methanol feed, can be used as the alkylating agent, reducing the need to co-inject water at least partially, if not completely. | 2018-06-07 |
20180155256 | DUAL CATALYST SYSTEM FOR PROPYLENE PRODUCTION - Embodiments of processes for producing propylene utilize a dual catalyst system comprising a mesoporous silica catalyst impregnated with metal oxide and a mordenite framework inverted (MFI) structured silica catalyst downstream of the mesoporous silica catalyst, where the mesoporous silica catalyst includes a pore size distribution of at least 2.5 nm to 40 nm and a total pore volume of at least 0.600 cm | 2018-06-07 |
20180155257 | TREATING C8-C10 AROMATIC FEED STREAMS TO PREPARE AND RECOVER TRANSMETHYLATED BENZENES - Methods are provided for the treatment of a feed stream containing C9 aromatic components to produce mesitylene-containing products. The methods include hydrodealkylating the feed stream to remove C2 and higher alkyl groups from the aromatic components and transalkylating the feed stream to rearrange the distribution of methyl groups among the aromatic components. Disclosed methods also include the treatment of a hydrocarbon feedstock by hydrodealkylation and/or transalkylation in order to produce a hydrocarbon product having an increased mass percentage of mesitylene. | 2018-06-07 |
20180155258 | ACETYLENE REMOVAL FROM LIGHT HYDROCARBON MIXTURES BY METAL-ORGANIC FRAMEWORK EXHIBITING DUAL SIZE AND CHEMICAL SELECTIVITIES - The present invention provides a gas separation system and a gas separation method capable of separating various types of hydrocarbon gas with high selectivity, and a gas separation system is for separating one type or more of hydrocarbon gases from mixed gas consisting of two types or more of hydrocarbon gases; having a porous metal-organic complex having pores determined by metal ion-containing planar ligands facing each other and pillar ligands coordinating between the planar ligands, and a controller for controlling at least a pressure of the mixed gas; and in which the pressure is controlled to control adsorption of the hydrocarbon gas to the porous metal-organic complex or desorption thereof from the porous metal-organic complex. | 2018-06-07 |
20180155259 | METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUNDS - Provided is an efficient method for producing a fluorine-containing compound without the need for a rectification column involving numerous stages, extractive distillation, etc. The method for producing a fluorine-containing compound includes the step of supplying a composition containing a mixture to a dehydrohalogenation step, the mixture being at least one member selected from the group consisting of mixtures of at least one fluoroolefin and at least one hydrofluorocarbon, the boiling points of which are close to each other, azeotropic mixtures of at least one fluoroolefin and at least one hydrofluorocarbon, and pseudo-azeotropic compounds of at least one fluoroolefin and at least one hydrofluorocarbon. | 2018-06-07 |
20180155260 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN - The present invention provides a method for producing a target fluorine-containing olefin with high conversion and selectivity using a process comprising a dehydrofluorination reaction of a hydrofluorocarbon. The method comprises a first reaction step comprising subjecting a hydrofluorocarbon to dehydrofluorination in the presence of a catalyst. The hydrofluorocarbon is a compound represented by Formula (1): R | 2018-06-07 |
20180155261 | METHOD FOR CONVERTING NATURAL GAS TO DIMETHYL ETHER - Systems and methods for upgrading natural gas that may include the division of a natural gas feed steam into two parts—one that is partially oxidized into syngas and a second that is “dry” reformed into syngas with the assistance of heat from the partial oxidation. Each of the resulting syngas products may then be combined, and after water is condensed from the syngas, the combined syngas product may be converted to dimethyl ether. | 2018-06-07 |
20180155262 | OXIDATION OF LIMONENE - The invention discloses a process for the oxidation of limonene, comprising the reaction of limonene with hydrogen peroxide in the presence of a catalyst containing atoms and/or ions of at least one metal, selected from the group consisting of molybdenum, tungsten, scandium, vanadium, titanium, lanthanum, zirconium, praseodymium, neodymium, samarium, europium, terbium, dysprosium, erbium or ytterbium, characterised in that the molecular weight of the catalyst is less than 2,000 g/mol and that the reaction is performed at a pH value of more than 7.5. | 2018-06-07 |
20180155263 | METHODS AND CATALYSTS FOR CONVERTING METHANE TO METHANOL - The invention encompasses methods of directly converting methane- to methanol The invention further encompasses catalysts that efficiently afford this transformation at low temperatures. Exemplary embodiments encompassed by the invention include a gas stream containing methane gas and oxygen,—which is passed over an oxygen-activated catalyst to directly form methanol | 2018-06-07 |
20180155264 | CATALYTIC OXIDATION OF 3,5,5-TRIMETHYLCYCLOHEXA-3-ENE-1-ONE ( -ISOPHORONE) WITH HYDROGEN PEROXIDE TO AFFORD 2,6,6-TRIMETHYL-2-CYCLOHEXENE-1,4-DIONE (KETO-ISOPHORONE) - The present invention provides a novel process for producing 2,6,6-trimethyl-2-cyclohexene-1,4-dione (keto-isophorone) by catalytic oxidation of 3,5,5-trimethylcyclohexa-3-ene-1-one (β-isophorone) with hydrogen peroxide as the oxidant. In particular, the novel process includes phase transfer reagent in a biphasic system including an organic phase and an aqueous phase wherein the biphasic system includes 1) a tungsten polyoxyometallate as catalyst and hydrogen peroxide, and/or 2) a mixture of a) a mineral acid, b) hydrogen peroxide, and c) a metal tungstate. | 2018-06-07 |
20180155265 | 3,6-DICHLOROSALICYLIC ACID COMPOUNDS AND RELATED SYNTHETIC PROCESSES - The present disclosure relates, in general, to 5-halo-3,6-dichlorosalicylic acid compounds, 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for preparing 5-halo-3,6-dichlorosalicylic acid compounds, processes for preparing 5-halo-3,6-dichlorosalicyaldehyde compounds, processes for preparing 3,6-dichlorosalicylic acid compounds, and processes that employ such compounds as intermediates in the preparation of the herbicide dicamba. | 2018-06-07 |
20180155266 | 4-HYDROXYBUTYRIC ACID ANALOGS - This invention relates to novel derivatives of 4-hydroxybutyric acid and prodrugs thereof, and pharmaceutically acceptable salts of the foregoing. This invention also provides pharmaceutical compositions comprising a compound of this invention and the use of such compositions in methods of treating narcolepsy, fibromyalgia, other disorders or conditions that are beneficially treated by improving nocturnal sleep or by administering sodium oxybate. | 2018-06-07 |
20180155267 | 7-METHYL-3-METHYLENE-7-OCTENAL ACETAL COMPOUND AND METHODS FOR PRODUCING ALDEHYDE COMPOUND AND ESTER COMPOUND USING THE SAME - There are provided methods of efficiently producing compounds that are, for example, sex pheromones of San Jose Scale. For example, there is provided a method for producing a 7-methyl-3-methylene-7-octenyl carboxylate compound (4), the method including the steps of: hydrolyzing a 7-methyl-3-methylene-7-octenal acetal compound (1) to obtain 7-methyl-3-methylene-7-octenal (2); reducing the 7-methyl-3-methylene-7-octenal (2) to obtain 7-methyl-3-methylene-7-octenol (3); and esterifying the 7-methyl-3-methylene-7-octenol (3) to obtain a 7-methyl-3-methylene-7-octenyl carboxylate compound (4). | 2018-06-07 |
20180155268 | NOVEL PRODUCTION METHOD OF HIGHLY UNSATURATED FATTY ACID ETHYL ESTER - The present invention provides a method of producing/purifying highly unsaturated fatty acids and/or derivatives thereof while suppressing deterioration of a silver salt aqueous solution, in production/purification of highly unsaturated fatty acids and/or derivatives thereof using the aqueous solution of silver salt. The present invention also contacts or mixes a mixture having a peroxide value (POV) of 10 or smaller with an aqueous solution of silver salt, in a method of purifying highly unsaturated fatty acids and/or derivatives thereof from a mixture comprising highly unsaturated fatty acids and/or derivatives thereof. | 2018-06-07 |
20180155269 | METHOD OF PURIFYING NITRATED AROMATIC COMPOUNDS FROM A NITRATION PROCESS - A process for removing impurities from crude nitrated aromatic products obtained during the nitration of aromatic compounds. The nitrated aromatic products are purified by treatment with ammonia washing followed by caustic washing. The nitrophenolic-containing wash waters are treated to recover dissolved organics and ammonia, and the stripped ammonia-wash effluent is incinerated. Carbon dioxide, which can accumulate in the process, is purged to the caustic washer. | 2018-06-07 |
20180155270 | PROCESS FOR PREPARATION OF CINACALCET INTERMEDIATE AND CINACALCET HYDROCHLORIDE - The present invention provides one pot process for preparation of highly pure unsaturated cinacalcet hydrochloride (II) comprising: i) converting 3-(trifluromethyl) cinnamic acid (III) into 3-(3-(trifluoromethyl)phenyl)prop-2-en-1-ol (IV), ii) converting 3-(3-(trifluoromethyl)phenyl)prop-2-en-1-ol (IV) to compound (V), wherein R is Cl, Br, I, tosylate and mesylate, Formula (V) iii) reacting compound (V) with (R)-1-(1-Naphthyl) ethylamine (VI) in presence of base followed by treatment with hydrochloric acid. The present invention further provides conversion of unsaturated cinacalcet hydrochloride (II) to cinacalcet hydrochloride (I). | 2018-06-07 |
20180155271 | SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES - The present disclosure describes methods for silylating aromatic organic substrates, and associated chemical systems, said methods comprising or consisting essentially of contacting the aromatic organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the aromatic substrate. | 2018-06-07 |
20180155272 | PROCESS FOR RECOVERING AMINOALCOHOLS AND GLYCOLS FROM AQUEOUS STREAMS OF TAURINE PRODUCTION - There is disclosed an extraction process for recovering aminoalcohols and glycols from aqueous streams of taurine production. The aqueous streams which contain aminoalcohols and/or glycols are first mixed with a base to increase pH and then extracted with C | 2018-06-07 |
20180155273 | CRYSTALLINE SOLID FORMS OF THE ACETATE SALT OF (1S,3S,4R)-4-((3AS,4R,5S,7AS)-4-(AMINOMETHYL)-7A-METHYL-1-METHYLENEOCTAHY- DRO-1H-INDEN-5-YL)-3-(HYDROXYMETHYL)-4-METHYLCYCLOHEXANOL - The present invention is generally directed to novel crystalline forms of the acetate salt of (1S,3S,4R)-4-((3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol and processes for their preparation. | 2018-06-07 |
20180155274 | IDENTIFIABLE CHEMICAL PRODUCT - The invention is a process for manufacturing a chemical product which may be later identified and distinguished from similar chemical products, and comprises the steps of (i) forming a reaction mixture comprising chemical intermediate A, chemical intermediate B and marker chemical M (ii) providing the conditions which enable chemical intermediate A and chemical intermediate B to react together to form chemical product C, and for marker chemical M to react either with chemical intermediate A to form a marker product AM or with chemical product C to form a marker product CM (iii) after said reactions have taken place, separating a mixture of product C with product AM and/or a mixture of product C with marker product CM from the reaction mix tune wherein product AM and product CM are both distinguishable from product C by analysis. By using the method of the invention, the marked product is formed in situ and in a mixture with unmarked product. | 2018-06-07 |
20180155275 | A Novel Neuroprotective and Neurorestorative N-Propargyl Caffeamide (PACA) and Use as A Treatment for Neurodegenerative Diseases - The present invention is directed to compounds, pharmaceutical compositions, and related methods of treatment and/or prevention for neurodegenerative diseases, such as Parkinson's disease. | 2018-06-07 |
20180155276 | PHTHALONITRILE COMPOUND - The present application can provide a phthalonitrile compound and a use thereof. The present application can provide a phthalonitrile compound capable of forming a phthalonitrile resin by self-curing or of serving as a curing agent after being mixed with another phthalonitrile compound, and a use of the phthalonitrile compound. The phthalonitrile compound can form a phthalonitrile resin by rapid self-curing even at a low temperature and does not create any defects resulting from the use of a conventional curing agent. Also, the phthalonitrile compound can be applied as a curing agent after being mixed with another compound, in which case, even if the content of the compound applied as a curing agent increases, the total content of the phthalonitrile resin obtained does not decrease, and thus a resin exhibiting an excellent degree of cure can be provided. | 2018-06-07 |
20180155277 | GAS GENERATING AGENT, AND METHOD FOR PRODUCING FOAM USING THE SAME - The gas generating agent of the present invention comprises an oxalic acid salt of an aminoguanidine compound represented by general formula (1) below. | 2018-06-07 |
20180155279 | ARYL ETHERS AND USES THEREOF - The present disclosure relates to HIF-2α inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2α scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo. | 2018-06-07 |
20180155280 | PREPOLYMERS EXHIBITING RAPID DEVELOPMENT OF PHYSICAL PROPERTIES - Hydroxyl-containing bis(alkenyl) ethers can be incorporated into the backbone of polythioether prepolymers and can be used as curing agents in thiol-terminated polythioether prepolymer compositions. Cured sealants prepared using compositions containing hydroxyl-containing bis(alkenyl) ether-containing polythioether prepolymers and/or hydroxyl-containing bis(alkenyl) ether curing agents exhibit improved physical properties such as rapid curing and compatibility with fillers suitable for use in aerospace sealant applications. | 2018-06-07 |
20180155281 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF - Disclosed herein are novel compounds of formula (I) as described herein: | 2018-06-07 |
20180155282 | PSYCHOTROPIC AGENTS AND USES THEREOF - Novel amisulpride derivatives and pharmaceutical compositions thereof are disclosed. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may have better membrane permeability compared to amisulpride. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for antagonizing dopamine and/or serotonin (e.g., 5-HT2a) and/or α2 receptor in a subject, either individually or in combination with other CNS active agents. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for treating one or more conditions responsive to modulation of dopamine and/or serotonin (e.g., 5-HT2a) and/or α2 receptor in a subject, either individually or in combination with other CNS active agents. The amisulpride derivative disclosed herein or a pharmaceutical composition thereof may be used for treating one or more disorders associated with an abnormality in levels of dopamine and/or serotonin in the brain, either individually or in combination with other CNS active agents. | 2018-06-07 |
20180155283 | DOPAMINE D2 RECEPTOR LIGANDS - The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopammode inergic activity. The present invention relates to novel compounds that modulate dopamine D2 receptors. In particular, compounds of the present invention show functional selectivity at the dopamine D2 receptors and exhibit selectivity downstream of the D2 receptors, on the 0-arrestin pathway and/or on the cAMP pathway. | 2018-06-07 |
20180155284 | PROCESSES TO PRODUCE BRIVARACETAM - The present invention provides a scalable synthesis of enantiomerically pure brivaracetam, and related derivatives. | 2018-06-07 |
20180155285 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES - Compounds of formula (I) as described hereinprocesses for their production and their use as anti-cancer agents. | 2018-06-07 |
20180155286 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS - The present disclosure describes a method to treat conditions, including bacterial infections and cancer, using a photosensitive compound that, upon exposure to white light, can be activated. The photosensitive compound can also interact synergistically with antibiotics used concomitantly to kill drug-resistant bacteria. The photosensitive compounds can also be used to inhibit the proliferation of cancer cells. | 2018-06-07 |
20180155287 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN - The invention relates to the compounds of formula I, formula II, formula III, formula IV and formula V or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I, formula II, formula III, formula IV or formula V and methods for the treatment of inflammation and pain may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, oral solution, buccal mucosal layer tablet, parenteral administration, syrup, or injection. Such compositions may be used to treatment of pain, oral mucosal inflammatory or oral infectious diseases. | 2018-06-07 |
20180155288 | UV Absorbing Compounds, Compositions Comprising Same and Uses Thereof - There is provided a range of novel compounds which have been demonstrated to have useful electromagnetic radiation absorbing properties. These compounds will find use in a range of applications such as active components in sunscreen formulations, paints, plastics, fabrics, glass and UV protective coatings. | 2018-06-07 |
20180155289 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF - This invention is in the field of medicinal chemistry. In particular, the invention relates to mixed disulfide conjugates of thienopyridine compounds, and their use as therapeutics for the treatment, amelioration, and prevention of cardiovascular diseases. | 2018-06-07 |
20180155290 | Improved Process for the Preparation of Aripiprazole with Reduced Particle Size - The present invention relates to process for preparation of Aripiprazole with reduced particle size having dehydro impurity less than 0.1%. | 2018-06-07 |
20180155291 | NEW CRYSTAL FORM OF LENVATINIB METHANESULFONATE SALT AND PREPARATION METHOD THEREOF - The present disclosure relates to a novel crystalline form of lenvatinib mesylate and the preparation method thereof. The novel crystalline form of mesylate of the present disclosure can be used for treating invasive and differentiated thyroid cancer. The novel crystalline form of mesylate of the present disclosure has good solubility, stability, and remarkable purification effect in process. The preparation method of this novel crystalline form is simple, low cost, and has an important value for future optimization and development of the drug. | 2018-06-07 |
20180155292 | NOVEL 5-HT2 ANTAGONISTS - The present invention relates to 1-amidino-3-aryl-2-pyrazoline derivatives of the general formula I The invention specifically relates to such derivatives which exhibit antagonizing activity towards serotonin 5-HT | 2018-06-07 |
20180155293 | Substituted Heterocyclyl Derivatives as CDK Inhibitors - The present invention provides substituted heterocyclyl derivatives of formula (I), which are therapeutically useful, particularly as selective transcriptional CDK inhibitors including CDK7, CDK9, CDK12, CDK13 and CDK18, more particularly transcriptional CDK7 inhibitors. These compounds are useful in the treatment and prevention of diseases and/or disorders associated with selective transcriptional CDKs in a mammal. The present invention also provides preparation of the compounds and pharmaceutical formulations comprising at least one of the substituted heterocyclyl derivatives of formula (I) or a pharmaceutically acceptable salt or a stereoisomer thereof. | 2018-06-07 |
20180155294 | FIPRONIL PRODUCTION PROCESS - An improved oxidation process for preparing 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulphinyl-pyrazole, of formula (I) is described. The process includes admixing 5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylthiopyrazole of formula (II) with dichloroacetic acid and hydrogen peroxide in the presence of a strong acid. | 2018-06-07 |
20180155295 | CXCR4 CHEMOKINE RECEPTOR MODULATORS - Provided herein are small molecule modulators of CXCR4 activity (e.g., agonists, antagonists, inverse agonists, partial agonists), and methods of use thereof (e.g., for the treatment of disease). | 2018-06-07 |
20180155296 | SPIROCYCLOHEPTANES AS INHIBITORS OF ROCK - The present invention provides compounds of Formula (I): | 2018-06-07 |
20180155297 | INHIBITORS OF ACK1/TNK2 TYROSINE KINASE - Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new Ack1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I through IV are disclosed. | 2018-06-07 |
20180155298 | PYRIMIDINE COMPOUNDS CONTAINING ACIDIC GROUPS - The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of viral infections and cancers. | 2018-06-07 |
20180155299 | Azasteroidal Mimics - An azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic is formed via an oxocycloalkenyl isoxazolium anhydrobase and its dimer. The dimer can be used to form mono- and dihydrazones, which can be an azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic. A method of preparation of the dimer and the azasteroid mimic or an intermediate for the preparation of an azasteroid and azasteroid mimic occurs with hydrazonation and, optionally, a subsequent dehydrazonation. The dimer can be converted by inserting a nitrogen atom into the six membered ring of to a C-17 position cyclohexenone moiety of the dimer to yield a reduced tetrazolo[1,5-a]azepin-8-yl group. A subsequent hydrozone formation at a benzylic ketone can be carried out to generate an azasteroid mimic with a (triazol-4-yl)imino substituent. Monohydrazones can be converted to their thione equivalents. | 2018-06-07 |
20180155300 | SOLID STATE FORMS OF TRISODIUM VALSARTAN: SACUBITRIL - Solid state forms of trisodium vaisartan:sacubitril, processes for their preparation, pharmaceutical compositions containing such solid state forms and treatment methods using the pharmaceutical compositions are described. | 2018-06-07 |
20180155301 | ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS - This invention relates to methods for controlling parasitic infestations of animals and their environments, and, more particularly, to methods using isoxazolines to control parasites in or on animals or in their environments, as well as treat parasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzamides) and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides). This invention also relates to compositions comprising the isoxazolines for use in such methods, the use of the isoxazolines to make medicaments for use in such methods, and kits comprising the isoxazolines for carrying out such methods. This invention further relates to the use of the isoxazolines as medicaments, particularly medicaments that can be used in the above-referenced method. | 2018-06-07 |
20180155302 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS - The present invention relates to compound of formula (I), or stereoisomers and pharmaceutically acceptable salts as muscarinic M1 receptor positive allosteric modulators. This invention also relates to methods of preparing such compounds and pharmaceutical compositions comprising such compounds. The compounds of this invention are useful in the treatment of various disorders that are related to muscarinic M1 receptor. | 2018-06-07 |