23rd week of 2016 patent applcation highlights part 29 |
Patent application number | Title | Published |
20160160219 | COMPOSITION CONTAINING PPAR-gamma NEDDYLATION INHIBITOR FOR INHIBITING ADIPOCYTE DIFFERENTIATION AND USE THEREOF - Provided is a method for suppressing an adipose differentiation comprising administering to a subject in need thereof a PPAR-v neddylation inhibitor for inhibiting adipocyte differentiation and a method for screening an adipocyte differentiation inhibitor using PPAR-v neddylation associated with adipocyte differentiation. The inhibitor of a neddylation pathway of PPAR-v inhibits the differentiation from mesenchymal stem cells to mast cells, and thus can be effectively used to treat obesity, and particularly, can be also useful in the treatment of severe obesity which cannot be excepted to be treated by existing obesity treatment agents. | 2016-06-09 |
20160160220 | Methods and Compositions for Treating Autoimmune Disorders by Targeting Kv1.3 Ion Channels with Functionalized Lipid-Derived Nanovesicles - Synthesis and pharmaceutical compositions of antibody-functionalized nanovesicles encapsulating ion channel knockout siRNA, and methods of treating autoimmune diseases associated with increased expression and/or hyperactivity of T cells by selectively targeting memory T cells with the nanoparticles, which deliver their siRNA cargo into the cytosol of the T | 2016-06-09 |
20160160221 | NOVEL STRINGENT SELECTABLE MARKERS - The present invention relates to nucleic acid constructs comprising selectable marker genes in a multicistronic transcription unit for use in the generation and selection of eukaryotic host cells for expression of a gene product of interest. For increased stringency of selection, the coding sequence of the selectable marker may be directed preceded by a relatively short functional open reading frame to reduce the efficiency of translation of the selectable marker, and/or the amino acid sequence of the selectable marker may comprise one or more mutations that reduce the level of resistance provide by the mutated marker as compared to its wild type counterpart. The invention further relates to methods for generating eukaryotic host cells for expression of a gene product of interest, wherein these nucleic acid constructs are used, and to methods for producing a gene product of interest wherein thus generated host cells are applied. | 2016-06-09 |
20160160222 | DNA MOLECULES AND METHODS - The present application discloses a DNA molecule comprising a modified Group II intron which does not express the intron-encoded reverse transcriptase but which contains a modified selectable marker gene in the reverse orientation, wherein the marker gene comprises a Group I intron in forward orientation of causing expression in a bacteria cell of the class Clostridia and wherein the DNA molecule comprises sequences that allow for the insertion of the RNA transcript of the Group II intron in the chromosome of a bacterial cell of the class Clostridia. A method of introducing a nucleic acid molecule into a site of a DNA molecule in a bacterial cell of the class Clostridia is also provided. The DNA molecule and the method are useful for making mutations | 2016-06-09 |
20160160223 | RECOMBINANT MICROORGANISMS EXHIBITING INCREASED FLUX THROUGH A FERMENTATION PATHWAY - The invention provides a recombinant, carboxydotrophic | 2016-06-09 |
20160160224 | CRYPTOSPORIDIUM TRANSFECTION METHODS AND TRANSFECTED CRYPTOSPORIDIUM CELLS - This disclosure describes, in one aspect, a method of transfecting a | 2016-06-09 |
20160160225 | PEPPER WITH NOVEL FLAVOR - The present invention relates to a pepper plant ( | 2016-06-09 |
20160160226 | GENE FOR INCREASING PLANT WEIGHT AND METHOD FOR USING THE SAME - A gene having novel functions is searched for, by which plant weight (that is, biomass level) can be increased and by which substance productivity can be increased or decreased. A chimeric protein is expressed in which a transcriptional factor comprising the amino acid sequence shown in SEQ ID NO: 2, 4, or 6 is fused to a functional peptide that converts an arbitrary transcriptional factor into a transcriptional repression factor. | 2016-06-09 |
20160160227 | GENE FOR INCREASING PLANT WEIGHT AND METHOD FOR USING THE SAME - A gene having novel functions is searched for, by which plant weight (that is, biomass level) can be increased and by which substance productivity can be increased or decreased. A chimeric protein is expressed in which a transcriptional factor comprising the amino acid sequence shown in SEQ ID NO: 2, 4, or 6 is fused to a functional peptide that converts an arbitrary transcriptional factor into a transcriptional repression factor. | 2016-06-09 |
20160160228 | TRANSGENIC ALOE PLANTS FOR PRODUCTION OF PROTEINS AND RELATED METHODS - The present inventions provide transgenic aloe plants and recombinant constructs for transforming aloe plants, aspects of which, may be applied to other monocots. The recombinant constructs may include one or more DNA sequences encoding mammalian proteins and at least one promoter capable of directing the expression of recombinant proteins in an aloe plant. The present inventions also provide methods for constructing and reproducing a transgenic aloe plant. The present inventions include methods for transfection of an aloe plant with several genes of interest simultaneously. The aloe plant production methods of the inventions may provide the potential to inexpensively and more safely mass-produce some biologically active compounds including biopharmaceuticals for disease therapy, diagnosis and prevention, and is more accessible to the less affluent countries. The aloe plant production methods may also produce proteins for cosmetics. | 2016-06-09 |
20160160229 | METHODS OF PRODUCING ANTIBODY-RICH CANNABIS AND HONEYSUCKLE PLANTS - A method of producing antibody-rich | 2016-06-09 |
20160160230 | TRANSGENIC MAIZE - The present invention provides a method of producing transgenic plants which are drought resistant, plants obtainable by the method and uses thereof. | 2016-06-09 |
20160160231 | USE OF POLYPEPTIDES AND NUCLEIC ACIDS FOR IMPROVING PLANT GROWTH, STRESS TOLERANCE AND PRODUCTIVITY - Transgenic plants that over-express a Big Grain 2 (BG2) gene and methods of using such for improving the growth, productivity, or stress tolerance of a plant. | 2016-06-09 |
20160160232 | ALS INHIBITOR HERBICIDE TOLERANT MUTANT PLANTS - The present invention relates to an ALS inhibitor herbicide tolerant polyploid plants, such as | 2016-06-09 |
20160160233 | Downy Mildew Resistance Providing Genes in Sunflower - Described herein are downy mildew resistant genes in sunflower and downy mildew resistance sunflower plants. Specifically, the present invention relates to sunflower plants being resistant to the plant pathogen downy mildew, wherein the plant comprises a downy mildew resistance conferring gene encoding a protein including the amino acid sequence as shown in SEQ ID No. 2 or SEQ ID No. 4 and wherein the expression of the resistance conferring gene is reduced as compared to the expression of said resistance conferring gene in a sunflower plant not being resistant to the plant pathogen downy mildew or the enzymatic activity of said protein is reduced as compared to the enzymatic activity of said protein in a sunflower plant not being resistant to the plant pathogen downy mildew. | 2016-06-09 |
20160160234 | COMPOSITION FOR TRANSFERRING GENE TO CELL - Disclosed are a composition for gene transfer, a method for introducing a gene into cell of a non-human animal, a method for introducing a gene into an in vitro cell, and a kit for gene transfer. The composition comprises (A) at least one lipid selected from the group consisting of sorbitan sesquioleate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan trioleate, sorbitan monooleate, L-α-phosphatidylinositol, L-α-dioleoyl phosphatidylethanolamine, octadecylamine, hexadecylamine, DOTAP, and cardiolipin; (B) at least one protein selected from the group consisting of albumin, casein, gelatin, and sericin; and (C) at least one positively charged substance selected from the group consisting of protamine sulfate, polyarginine, polylysine, polyethyleneimine, and hexadimethrine bromide. | 2016-06-09 |
20160160235 | MINIMAL PIGGYBAC VECTORS FOR GENOME INTEGRATION - Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into target cells using the genetic delivery systems. | 2016-06-09 |
20160160236 | SELECTABLE MARKERS AND RELATED METHODS - The invention relates to newly identified selectable marker systems, cells for use in a selectable marker system, and methods for using the selectable marker systems. | 2016-06-09 |
20160160237 | Mitochondrial Collection and Concentration, and Uses Thereof - Preparations and methods of producing a concentrated mitochondrial preparation using inverted phase centrifugation are disclosed. The methods include centrifuging a closed-bottom tube containing a heavy phase including a mitochondrial suspension in the portion of the tube proximal to the axis of rotation and a light phase in the portion of the tube distal to the axis of rotation. The centrifugation causes the suspension to form a concentrated mitochondrial layer at the interface between the heavy layer and the light layer, and the fluid at this interface is collected to produce the concentrated mitochondrial preparation. The concentrated mitochondrial preparation can be used for various applications, including in vitro fertilization applications. | 2016-06-09 |
20160160238 | HETEROZYGOUS MODIFICATIONS OF TUMOR SUPPRESSOR GENES - Animals genomically modified to have heterozygous modifications of one or more tumor suppressor genes are disclosed. | 2016-06-09 |
20160160239 | METHOD FOR CYCLING BIOMASSES BETWEEN MUSHROOM CULTIVATION AND ANAEROBIC BIOGAS FERMENTATION, AND FOR SEPARATING AND DRYING A DEGASSED BIOMASS - The present invention is related to recycling of fermentable and metabolizable biomass materials for sequentially performing a cultivation of fungal cells and for producing biogas by anaerobic fermentation of said biomass materials. | 2016-06-09 |
20160160240 | PROCESSING BIOMASS - Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to proceed ethanol and/or butanol, e.g., by fermentation. | 2016-06-09 |
20160160241 | NOVEL YEAST STRAINS - Several mutated strains of | 2016-06-09 |
20160160242 | METHOD OF PRODUCING ALCOHOL FROM CELLULOSE-CONTAINING BIOMASS - A method of producing alcohol from cellulose-containing biomass includes steps (1) to (8): step (1): pretreating a cellulose-containing biomass; step (2): saccharifying the pretreated cellulose-containing biomass obtained in step (1) with a saccharification enzyme; step (3): removing a saccharification residual solid from a saccharification treated product obtained in step (2); step (4): culturing an alcohol fermentation microorganism with an aqueous sugar solution obtained in step (3) as a fermentation raw material; step (5): removing the alcohol fermentation microorganism from a culture liquid containing the alcohol fermentation microorganism obtained in step (4); step (6): distilling the alcohol fermentation liquid obtained in step (5) to recover alcohol; step (7): passing and filtering a distillation residual liquid obtained in step (6) through a reverse osmosis membrane; and step (8): performing treatment of discharging a retentate obtained in step (7). | 2016-06-09 |
20160160243 | Biological Production of Multi-Carbon Compounds from Methane - Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH | 2016-06-09 |
20160160244 | Microorganisms Engineered to Produce Phenol and Its Derivatives - Novel methods for the in vivo production of phenol from renewable substrates using a recombinant microorganism (FIG. | 2016-06-09 |
20160160245 | METHOD OF PRODUCING SUCCINIC ACID AND OTHER CHEMICLAS USING FACILITATED DIFFUSION FOR SUGAR IMPORT - This invention relates to the production of succinic acid and other chemicals derived from phosphoenolpyruvate (PEP) by fermentation with a microorganism in which the fermentation medium contains one or more sugars, and in which one or more of the sugars is imported into the cell by facilitated diffusion. As a specific example, succinic acid is produced from a glucose-containing renewable feedstock through fermentation using a biocatalyst. Examples of such a biocatalyst include microorganisms that have been enhanced in their ability to utilize glucose as a carbon and energy source. The biocatalysts of the present invention are derived from the genetic manipulation of parental strains that were originally constructed with the goal to produce one or more chemicals (for example succinic acid and/or a salt of succinic acid) at a commercial scale using feedstocks that include, for example, glucose, fructose, or sucrose. The genetic manipulations of the present invention involve the introduction of exogenous genes involved in the transport and metabolism of glucose or fructose into the parental strains. The genes involved in the transport and metabolism of glucose or fructose can also be introduced into a microorganism prior to developing the organism to produce a particular chemical. The genes involved in the transport and metabolism of sucrose can also be used to augment or improve the efficiency of sugar transport and metabolism by strains already known to have some ability for glucose utilization in biological fermentations. | 2016-06-09 |
20160160246 | Oleaginous Microorganism Disruption Process Using Supersonic Disperser and Method for Producing Bio-Oil Using Same - Provided are an oleaginous microorganism disruption process using a supersonic disperser and a method for producing bio-oil using the same. The method for producing bio-oil according to the present invention induces a cell disruption of oleaginous microorganisms without a separate drying process, thereby providing a method for continuously producing bio-oil in an economical and simple manner. In addition, the method of the present invention induces a cell disruption of oleaginous microorganisms without a heating process, thereby producing bio-oil without a change in physical properties due to the heat. | 2016-06-09 |
20160160247 | Modified algae strain and method of triacylglycerol accumulation using said strain - The present invention relates to a genetically engineered algae strain in which the expression of the CGI-58 gene or homologous gene thereof is silenced. The present invention further relates to a method of triacylglycerol accumulation using said genetically engineered diatom and/or diatom strain. | 2016-06-09 |
20160160248 | METHOD FOR PRODUCING PULVERULENT CERAMIDE - Disclosed herein is a pulverulent ceramide producing method that enables easily and efficiently extracting and separating ceramide from sugar beet pulp, and efficiently pulverizing the ceramide by spray drying. The pulverulent ceramide can be efficiently obtained by a process that includes concentrating, with and/or without adding water, a sugar beet pulp ethanol extract obtained by extraction of a sugar beet pulp (for example, such as a beet fiber) with ethanol, adding pectinase to the resulting concentrate and performing an enzymatic reaction, performing emulsification after inactivating the enzyme, and pulverizing the resulting emulsion using spray drying. | 2016-06-09 |
20160160249 | INCREASING METHIONINE YIELD - Process for the production of methionine or its derivatives by culturing a microorganism in an appropriate culture medium comprising a source of carbon and a source of sulfur. The microorganism and/or the culture medium are modified in such way that the methionine/carbon source yield is increased. The isolation of methionine or its derivates from the fermentation medium is also described. | 2016-06-09 |
20160160250 | HYPHOMICROBIUM SP. MICROORGANISM AND METHOD OF PRODUCING PYRROLOQUINOLINE QUINONE USING THE SAME - Provided are a | 2016-06-09 |
20160160251 | Optimized Method For Producing A Composition Containing Isomaltulose - The present invention relates to a method for producing a composition containing isomaltulose from a substrate containing sucrose. | 2016-06-09 |
20160160252 | POLYMERS IN BIOMASS SACCHARIFICATION BIOPROCESS - Methods and systems for increasing the yield of sugars from a biomass, such as a lignocellulosic biomass, are described. A non-ionic organic polymer is contacted with the biomass during the saccharification reaction, and the hydrolyzed mixture is separated using a filter into a permeate and a retentate, where the non-ionic organic polymer is present in the retentate. The retentate with the polymer is recycled to the hydrolysis mixture, which increased the yield of sugars using less saccharification enzymes. The methods thus allow for increased cost savings by reducing the amount of enzymes required to convert the biomass to sugars. | 2016-06-09 |
20160160253 | METHODS OF PROCESSING LIGNOCELLULOSIC BIOMASS USING SINGLE-STAGE AUTOHYDROLYSIS PRETREATMENT AND ENZYMATIC HYDROLYSIS - Methods of processing lignocellulosic biomass to fermentable sugars are provided which rely on hydrothermal pretreatment. Soft lignocellulosic biomass feedstock is pretreated in a single-stage pressurized hydrothermal pretreatment to very low severity. The pre-treated biomass is hydrolysed, typically as a whole slurry, using enzymatic hydrolysis catalysed by an enzyme mixture comprising endoglucanase, exoglucanase, β-glucosidase, endoxylanase, and β-xylosidase activities at activity levels in nkat/g glucan of endoglucanase of at least 1100, exoglucanase of at least 280, β-glucosidase of at least 3000, endoxylanase of at least 1400, and β-xylosidase of at least 75, so as to produce a hydrolysate in which the yield of C5 monomers is at least 55% of the original xylose and arabinose content of the feedstock prior to pretreatment. | 2016-06-09 |
20160160254 | PLANTS EXPRESSING CELL WALL DEGRADING ENZYMES AND EXPRESSION VECTORS - Vectors for expression of proteins in plants are described. The proteins may be enzymes and the enzymes can be but are not limited to cell wall degrading enzymes. A number of plants designed to express specific cell wall degrading enzymes are provided. The plants may have industrial and/or agricultural applications. Methods and materials for making the expression vectors and for making the plants are provided. Processes for which the plants could be used in industrial and agricultural applications are also provided. | 2016-06-09 |
20160160255 | Methods and Materials for Producing 6-Carbon Monomers - This document describes biochemical pathways for producing 6-hydroxyhexanoic acid using a polypeptide having β-ketothiolase activity to form a 3-oxo-6-hydroxyhexanoyl-CoA intermediate. 6-hydroxyhexanoic acid can be enzymatically converted to adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine or 1,6-hexanediol. This document also describes recombinant hosts producing 6-hydroxyhexanoic acid as well as adipic acid, caprolactam, 6-aminohexanoic acid, hexamethylenediamine and 1,6-hexanediol. | 2016-06-09 |
20160160256 | METHOD FOR SYNTHESIZING SELECTIVELY LABELED RNA - The invention relates to a method for synthesizing a selectively labeled RNA, and an apparatus for performing the method. Specific segments or discrete residues within the RNA may be selectively labeled, and different segments may include different labels. | 2016-06-09 |
20160160257 | DITERPENE PRODUCTION IN YARROWIA - The present invention relates to a method for the production of a diterpene or a glycosylated diterpene, which method comprises: a. fermenting a recombinant microorganism of the genus | 2016-06-09 |
20160160258 | MONOCLONAL ANTIBODY PRODUCTION BY EBV TRANSFORMATION OF B CELLS - A method for producing a clone of an immortalised human B memory lymphocyte, comprising the step of transforming human B memory lymphocytes using Epstein Barr virus (EBV) in the presence of a polyclonal B cell activator. The method is particularly useful in a method for producing a clone of an immortalised human B memory lymphocyte capable of producing a human monoclonal antibody with a desired antigen specificity, comprising the steps of: (i) selecting and isolating a human memory B lymphocyte subpopulation; (ii) transforming the subpopulation with Epstein Barr virus (EBV) in the presence of a polyclonal B cell activator; (iii) screening the culture supernatant for antigen specificity; and (iv) isolating an immortalised human B memory lymphocyte clone capable of producing a human monoclonal antibody having the desired antigen specificity. | 2016-06-09 |
20160160259 | AUTOMATED DETECTION OF ASSAY-POSITIVE AREAS IN MICROFLUIDIC DEVICES - Methods are provided for the automated detection of assay-positive assay areas in a microfluidic device. When assays are performed in a microfluidic device, the configuration of the microfluidic circuit and its constituent circuit elements can determine where the reagents/analytes used in the assay can be located within the microfluidic circuit. Methods are provided for automatic identification of the size and shape of the assay areas based on a number of parameters which may include type of assay involved, shape and dimensions of microfluidic circuit elements, velocity and physical characteristics of the fluidic medium within the microfluidic circuit, physical/chemical properties of the analytes/reagents, and/or the number of cells being assayed. | 2016-06-09 |
20160160260 | Multi-Sample Laser-Scatter Measurement Instrument With Incubation Feature And Systems For Using The Same - An optical measurement instrument is an integrated instrument that includes an optical cavity with a light source, a sample cuvette, and an optical sensor. The light source and sensor are on a bench that is on a translational or rotational mechanical platform such that optical beam can be moved to multiple sample containers. The instrument can be used for taking measurements of organism concentration in multiple samples as a production tool for microbiology. Preferably, the instrument holds multiple, individually-loaded, independent fluid samples and determines bacteria concentration via a forward-scattering signal. The instrument can incorporate onboard incubation to promote bacterial growth in the samples during the test. In another aspect, the instrument can be a part of a network for medical diagnostic testing data where data is stored in a manner that is inherently untainted by patient identifiable information. | 2016-06-09 |
20160160261 | METHOD FOR ESTABLISHING RESISTANCE CHARACTERISTICS OF A BIOLOGICAL INDICATOR - A method is provided for establishing resistance characteristics of a biological indicator in a sterilization process using a sterilant vapor. The method includes the step of creating a biological indicator inactivation profile by obtaining differential sterilant vapor pressure values in a sterilization chamber during sterilant vapor injection and determining D-values as a function of the differential sterilant vapor pressure values obtained. The biological indicator inactivation profile, when represented as a function of differential sterilant vapor pressure, may be linear over the full range of inactivation. The biological indicator inactivation profile may be created by injecting the sterilant vapor into the sterilization chamber and measuring biological indicator survival at different differential sterilant vapor pressure values. The method may include providing biological indicator inactivation data during sterilization at a given sterilization chamber temperature and initial sterilant concentration for use in creating the biological indicator inactivation profile at another temperature and sterilant concentration. | 2016-06-09 |
20160160262 | TEST KITS INCLUDING ACTIVATED MEDIATORS FOR DETECTING ANALYTES - Activated mediators for detecting predetermined analytes in a sample, as well as kits including testing surfaces incorporating an enzyme-activated mediator are disclosed. The enzyme-activated mediator may have a first color prior to the application of a sample to the portion of the testing surface including the enzyme-activated mediator. The enzyme-activated mediator is configured to undergo a detectable color change to a second color different from the first color in response to the sample applied to the testing surface including a predetermined analyte reactive with the enzyme-activated mediator. Methods for making the testing surfaces and using the testing surfaces to detect analytes are also disclosed. | 2016-06-09 |
20160160263 | PERSONALIZED PROTEASE ASSAY TO MEASURE PROTEASE ACTIVITY IN NEOPLASMS - Disclosed herein, the invention pertains to methods and compositions that find use in diagnostic, prognostic and characterization of neoplasia samples based on the ability of a neoplasia sample to cleave a MTS molecule of the present invention. In some embodiments, a MTS molecule disclosed herein has the formula (A-X-B-C), wherein A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and C is a detectable moiety. | 2016-06-09 |
20160160264 | DIAGNOSTIC IN VITRO METHOD - Disclosed is a diagnostic in vitro method for determining the activity of thiopurine S-methyltransferase (TPMT) in individuals to be examined, characterized in that the content of urothione and/or jukathione in body fluids is determined. | 2016-06-09 |
20160160265 | DEVICES AND METHODS FOR THERMALLY-MEDIATED CHEMICAL REACTIONS - One aspect of the invention provides container for thermal cycling a plurality of samples in a microfluidic array. The container includes a plurality of walls defining an interior volume and a conductive member for heating the interior volume. Another aspect of the invention provides container for thermal cycling a plurality of samples in a microfluidic array. The container includes a plurality of walls defining an interior volume and a plurality of conductive members for heating an interior volume. Another aspect of the invention provides a container for thermal cycling a plurality of samples in a microfluidic array. The container includes a plurality of walls defining an interior volume and a first conductive member located in the interior volume and adapted to contact a first end of the microfluidic array. | 2016-06-09 |
20160160266 | WASHING-FREE TEMPLATE-READY PCR DETECTION METHOD FOR RNA - Provided in the present invention is a washing-free template-ready PCR detection method for RNA. On the basis of retaining the advantages of the original template-ready PCR method, i.e., there being no need to purify and extract the RNA, no need for a reverse transcription reaction, etc., the method of the present invention designs a probe for the restriction enzymes to thereby integrate the enzyme digestion reaction, so as to eliminate the interference of various pollution sources of double-stranded DNA with no need for a washing step. | 2016-06-09 |
20160160267 | COMPOSITION FOR EVALUATING OR PREDICTING PATIENTS THERAPEUTIC RESPONSE TO METHORMIN - The present invention relates to a biomarker for evaluating or predicting response of a patient to metformin, and use thereof. The present invention relates to a composition and a kit for evaluating or predicting therapeutic response of a patient to metformin, comprising an agent capable of detecting one or more microorganisms selected from the group consisting of | 2016-06-09 |
20160160268 | AMDINOCILLIN FOR RAPID DETERMINATION OF SUSCEPTIBILITY TO BETA-LACTAM ANTIBIOTICS - Described are methods for detecting susceptibility of a specimen to antibiotics, and particularly for enhancing such susceptibility testing for beta lactam antibiotics and antibiotics that bind to penicillin-binding proteins. The method comprises contacting the specimen with an oligonucleotide probe that specifically hybridizes with a target nucleic acid sequence region of ribosomal RNA. The target sequence is mature ribosomal RNA or at the splice site between a pre-ribosomal RNA tail and mature ribosomal RNA. Performing the method in the presence and absence of an antibiotic permits determination of antibiotic susceptibility. Rapid susceptibility testing is enabled by the addition of the PBP2-specific antibiotic, amdinocillin. | 2016-06-09 |
20160160269 | Fluid Identification System and Production and Use Thereof - A fluid identification system comprising a plurality of particles, each particle encapsulating therein at least one tracer material having an identifiable DNA, the at least one tracer material being encapsulated by an encapsulation material, wherein the particles are adapted to retain the at least one tracer material in an encapsulated form after exposure of the particles to a temperature of at least 75° C. and/or a pressure of at least 1000 psi (6.9×10 | 2016-06-09 |
20160160270 | METHODS FOR MODELING CHINESE HAMSTER OVARY (CHO) CELL METABOLISM - Embodiments of the present invention generally relate to the computational analysis and characterization biological networks at the cellular level in Chinese Hamster Ovary (CHO) cells. Based on computational methods utilizing a hamster reference genome, the invention provides methods for identifying a CHO cell line having a desired genetic trait, as well as for generating a desired CHO cell line having a genetic basis for a desired phenotype. Additionally, described herein are methods for constructing and analyzing in silico models of biological networks for CHO cells. | 2016-06-09 |
20160160271 | Real Time Microarrays - This invention provides methods and systems for measuring the binding of analytes in solution to probes bound to surfaces in real-time. | 2016-06-09 |
20160160272 | Arrays and Methods of Use - Methods are provided for producing a molecular array comprising a plurality of molecules immobilised to a solid substrate at a density which allows individual immobilised molecules to be individually resolved, wherein each individual molecule in the array is spatially addressable and the identity of each molecule is known or determined prior to immobilization. The use of spatially addressable low density molecular arrays in single molecule detection and analysis techniques is also provided. Novel assays and methods are also provided. | 2016-06-09 |
20160160273 | Lyophilized integrated composition for storage and manipulation of pyrophosphorolysis activated polymerization - The invention provides a method for lyophilizing integrated composition of pyrophosphorolysis activated polymerization (PAP) in an aqueous solution. It also provides lyophilized integrated PAP composition. Except for nucleic acid template, the integrated composition contains all components. For manipulation, simply add nucleic acid template in an aqueous solution to start amplification. In addition to the easy manipulation, the lyophilized integrated composition can be stored for prolonged period at ambiguous temperature. | 2016-06-09 |
20160160274 | MATERIALS AND METHODS FOR PROFILING MICRORNAS - The present invention provides materials and methods for detecting, quantifying, and/or high-throughput-profiling microRNAs. Advantageously, the present invention is more sensitive and specific than other currently-available miRNA qPCR assays. In addition, the present invention is convenient, easy-to-perform, and cost-effective. In one embodiment, the present invention provides a universal primer for reverse transcription of all miRNAs, a universal reverse primer for PCR amplification reaction, and universal probes. In another embodiment, the present invention provides assays that allow simultaneous detection and/or quantification of a plurality of target miRNAs using a single reverse transcription reaction. | 2016-06-09 |
20160160275 | WHOLE-GENOME AND TARGETED HAPLOTYPE RECONSTRUCTION - The present invention relates to methods for haplotype determination and, m particular, haplotype determination at the whole genome level as well as targeted haplotype determination. | 2016-06-09 |
20160160276 | OPTICAL ALIGNMENT TOOL - Provided is an inspection apparatus including: (a) a translucent or transparent plate having a bottom surface, at least a portion of the bottom surface having an opaque material printed thereon in a pattern having at least one transparent or translucent portion; and (b) a chamber disposed below the bottom surface, whereby light emitted from the chamber or through the chamber can pass through the at least one transparent or translucent portion. | 2016-06-09 |
20160160277 | METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE - The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which permit the sequential determination of nucleotide sequences in two distinct and separate regions on complementary strands of the double-stranded polynucleotide template. The two regions for sequence determination may or may not be complementary to each other. | 2016-06-09 |
20160160278 | In Situ Hybridization Method And Buffer - An improved method of in situ hybridization which relies on an improved formulation of the in situ hybridization buffer is described. In at least some formulations the buffer are non-toxic. The combination of Locked Nucleic Acid (LNA) comprising ISH probes and the improved ISH buffer are useful for detection of small non-coding RNA as well as in the manufacturing of ISH kits directed to the detection of such small non-coding RNA. Further disclosed is a method of semi-quantitative ISH and demonstration of the semi-quantitative ISHs diagnostic potential. | 2016-06-09 |
20160160279 | PROGNOSIS OF RESPONSE TO TREATMENT WITH ANTI-TNF-ALPHA IN PATIENTS WITH RHEUMATOID ARTHRITIS - The invention relates to the use of SNP rs3794271, and/or an SNP that is in total linkage disequilibrium with same, as a marker in predicting the response to treatment with anti-TNF in a patient with RA. The invention also relates to methods for predicting the response to treatment with anti-TNF, as well as for deciding on or recommending a treatment for a patient with RA, based on determining the genotype for rs3794271 and/or an SNP that is in total linkage disequilibrium with same. | 2016-06-09 |
20160160280 | METHODS OF PREDICTING TOXICITY - Described herein are compounds useful for the treatment and investigation of diseases, methods for the prediction of in vivo toxicity of compounds useful for the treatment and investigation of diseases, and methods of discovering and identifying compounds useful for the treatment and investigation of diseases that have reduced in vivo toxicity. | 2016-06-09 |
20160160281 | CYSTIC FIBROSIS GENE MUTATIONS - The present invention provides novel mutations of the CFTR gene related to cystic fibrosis or to conditions associated with cystic fibrosis. Also provided are probes for detecting the mutant sequences. Methods of identifying if an individual has a genotype containing one or more mutations in the CFTR gene are further provided. | 2016-06-09 |
20160160282 | Neprilysin Gene Polymorphism and Amyloid Beta Plaques in Traumatic Brain Injury - The invention relates to methods of diagnosing risk of amyloid β deposition following traumatic brain injury. The invention further relates to the discovery of a specific single nucleotide polymorphism in the neprilysin gene that is linked to an increased risk of amyloid β deposition after traumatic brain injury. | 2016-06-09 |
20160160283 | Methods of Detecting Kidney-Associated Diseases or Conditions - This invention provides methods of using phagocytic cells alone or in combination with non-phagocytic cells in the diagnosis, prognosis, or monitoring of kidney-associated diseases or conditions. The invention also provides methods of using phagocytic cells alone or in combination with non-phagocytic cells to identify markers of kidney-associated diseases or conditions. | 2016-06-09 |
20160160284 | Methods of Detecting Neurological or Neuropsychiatric Diseases or Conditions - This invention provides methods of using phagocytic cells alone or in combination with non-phagocytic cells in the diagnosis, prognosis, or monitoring of neurological or neuropsychiatric diseases or conditions. The invention also provides methods of using phagocytic cells alone or in combination with non-phagocytic cells to identify markers of neurological or neuropsychiatric diseases or conditions. | 2016-06-09 |
20160160285 | METHOD FOR DETECTING GENES SENSITIVE TO LOW-LEVEL IONIZING RADIATION, AND GENE DETECTED BY THE METHOD - A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation and related to suppressing thymic cancer, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous AKR/J mouse and a normal ICR mouse to low-level radiation. Thymus is collected therefrom, immunogenic and apoptotic genes are classified via microarray processing of the thymus. The genes are amplified and the levels of gene expression are measured. Thus, a gene having a specific reaction to radiation to be accurately detected by preventing the interference of confounding variables. | 2016-06-09 |
20160160286 | METHODS FOR DETERMINING CANCER RESISTANCE TO HISTONE DEACETYLASE INHIBITORS - Described herein are methods and compositions for determining whether a particular cancer is resistant to or susceptible to a histone deacetylase inhibitor or to histone deacetylase inhibitors. The methods include analysis of the expression levels of at least four biomarker genes associated with response to a histone deacetylase inhibitor. Also described herein are methods and compositions for increasing the likelihood of a therapeutically effective treatment in a patient, comprising an analysis of the expression levels of at least four biomarker genes associated with response to a histone deacetylase inhibitor. Also described herein are isolated populations of nucleic acids derived from a cancer sensitive to or resistant to a histone deacetylase inhibitor. Further described are kits and indications that are optionally used in conjunction with the aforementioned methods and compositions. | 2016-06-09 |
20160160287 | METHOD FOR DETERMINING THE RISK OF DEVELOPING RADIATION-INDUCED TOXICITY AFTER EXPOSURE TO RADIATION - The invention is in the art of medical treatments, in particular the treatment of tumors with ionizing radiation. It provides means and methods for predicting whether a subject is likely to develop radiation damage upon radiotherapy. The invention provides tools that allow individualized and optimized radiation treatment of a subject in need of a radiation treatment. The invention also provides methods of determining the risk of developing severe dyspnea after radiation treatment. More in particular, the invention relates to an in vitro method for predicting the risk of developing radiation induced toxicity comprising the steps of obtaining mitochondrial DNA from a sample of a subject, determining the number of non-synonymous variations present in at least one gene encoding a mitochondrial protein, attributing a value to the number of non-synonymous variations, wherein a higher value corresponds to a higher risk of developing radiation induced lung toxicity. | 2016-06-09 |
20160160288 | METHOD FOR DETERMINING NUCLEIC ACID COMPOSITION OF NUCLEIC ACID MIXTURE - The present invention provides a method for determining the nucleic acid composition in a total nucleic acid mixture comprising a first nucleic acid and a second nucleic acid. The method comprises: 1) treating the total nucleic acid mixture with a bisulfate, to convert the non-methylated cytosine in the total nucleic acid mixture into uracil, and obtain a converted total nucleic acid mixture; 2) subjecting the converted total nucleic acid mixture to multiplexed fluorescent quantitative PCR using a first set of amplification primers and a second set of amplification primers; and 3) based on the ratio R of the methylated amplification product to the non-methylated amplification product of the predetermined nucleic acid fragment, a methylation proportion M | 2016-06-09 |
20160160289 | EML4-ALK TRANSLOCATIONS IN LUNG CANCER - The present disclosure relates to methods for the diagnosis and evaluation of neoplastic disorders, particularly non-small cell lung cancer. Assays are described in which patient test samples are analyzed for the presence of one or more specific EML4-ALK fusion genes associated with neoplastic disorders. | 2016-06-09 |
20160160290 | METHODS AND BIOMARKERS FOR PREDICTING EFFICACY AND EVALUATION OF AN OX40 AGONIST TREATMENT - The present disclosure provides methods for predicting responsiveness of a subject having cancer to an OX40 agonist treatment by measuring the expression level of one or more biomarkers. Also provided are methods for monitoring pharmacodynamic activity of or responsiveness to an OX40 agonist treatment by measuring the expression level of one or more biomarkers. Further provided are methods related thereto for treating or delaying progression of cancer in a subject by administering an effective amount of an OX40 agonist to a subject. Specific biomarkers for all such methods are described herein. | 2016-06-09 |
20160160291 | COMPOSITIONS AND METHODS FOR CHARACTERIZING A DNA REPAIR VARIANT POLYPEPTIDE - As described below, the present invention provides quantitative homologous recombination assays developed to characterize the pathogenicity DNA repair polypeptides (e.g., BRCA1, BRCA2, Rad51) and provide urgently needed functional information on the significance of DNA repair variants of uncertain significance (VUS) alleles. The invention also provides a method of generating site-specific recombination at a genomic locus or site-specific genome editing by inhibiting replication at the genomic locus, e.g., involving contacting the genomic locus with polypeptides that specifically bind target sequences at the genomic locus. | 2016-06-09 |
20160160292 | Tyrosine Kinome - Protein kinases are important signaling molecules involved in tumorigenesis. Mutational analysis of the human tyrosine kinase gene family (98 genes) identified somatic alterations in ˜20% of colorectal cancers, with the majority of mutations occurring in NTRK3, FES, GUCY2F and a previously uncharacterized tyrosine kinase gene called MCCK/MLK4. Most alterations were in conserved residues affecting key regions of the kinase domain. These data represent a paradigm for the unbiased analysis of signal transducing genes in cancer and provide useful targets for therapeutic intervention. | 2016-06-09 |
20160160293 | BREAST CANCER TREATMENT WITH TAXANE THERAPY - The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including a taxane or a taxane derivative. The application also describes methods for treating subjects with breast cancer by screening them for the likelihood of the effectiveness of treating the cancer with a therapy including a taxane or a taxane derivative and administering the therapy in subjects when it is found that a taxane or a taxane derivative is likely to be effective. | 2016-06-09 |
20160160294 | METHODS AND MATERIALS FOR PREDICTING RESPONSE TO NIRAPARIB - This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature to predict response to niraparib. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature to predict response to niraparib are provided. | 2016-06-09 |
20160160295 | NON-CODING RNAS AND USES THEREOF - Provided herein are compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, provided herein are non-coding RNAs as diagnostic markers and clinical targets for cancer. | 2016-06-09 |
20160160296 | BIOMARKERS FOR COLORECTAL CANCER - Biomarkers and methods related to microbiota for predicting the risk of a disease, particularly colorectal cancer (CRC), are described. | 2016-06-09 |
20160160297 | METHODS AND COMPOSITIONS FOR DETECTING MUTATIONS IN THE HUMAN PI3KCA (PIK3CA) GENE - The invention comprises reagents and methods for detecting cancer-associated mutations in the human PI3KCA (PIK3CA) gene and assessing the patients based thereon. | 2016-06-09 |
20160160298 | DIAGNOSTIC METHODS FOR DETERMINING PROGNOSIS OF NON-SMALL CELL LUNG CANCER - Disclosed are methods for identifying early-stage non-small-cell lung cancer (NSCLC) patients who will have an unfavorable prognosis for the recurrence of lung cancer after surgical resection. The methods are based in part on the discovery that chromosomal copy number gains at Chr19, 34.7 Mb-35.6 Mb can be used for prognostic classification. The methods preferably use fluorescence in situ hybridization with fluorescently labeled nucleic acid probes to hybridize to patient samples to quantify the chromosomal copy number of this genetic locus. | 2016-06-09 |
20160160299 | SHORT EXOGENOUS PROMOTER FOR HIGH LEVEL EXPRESSION IN FUNGI - Provided herein are short exogenous fungi transcription promoter nucleic acid sequences and methods of using the exogenous fungi transcription promoter nucleic acid sequences to modulate transcription initiation or rate of transcription. | 2016-06-09 |
20160160300 | APPARATUS AND METHOD FOR STRETCHING A PELT ON A PELT BOARD - An apparatus is disclosed for stretching a pelt ( | 2016-06-09 |
20160160301 | PROCESS FOR RETANNING LEATHER - The present invention is directed to a process for retanning leather comprising the steps of: a) providing tanned or pre-tanned leather b) treating the tanned leather of step a) with a composition comprising hollow microspheres, preferably as an aqueous composition, the hollow microspheres have a true density of from 0.01 to 0.10 g/cm | 2016-06-09 |
20160160302 | FLUXING AGENT, PROCESS OF ITS PRODUCTION, AGGLOMERATION MIXTURE AND USE OF SLUG FROM SECONDARY METALLURGY - The invention relates to fluxing agents for the agglomeration process based on slag from the secondary metallurgy, the use of these fluxing agents in the process of agglomeration in the manufacture of the agglomerate designed for the use as a metallic charge in blast furnaces and a process of production of fluxing agents based on slag from the secondary metallurgy or based on a mixture of slag from the secondary metallurgy with other materials. | 2016-06-09 |
20160160303 | EXHAUST GAS TREATMENT METHOD AND EXHAUST GAS TREATMENT FACILITY - An exhaust gas treatment method includes: burning a combustible component in exhaust gas by causing the exhaust gas, which is produced in an electric furnace, to flow into a slag holding furnace and supplying oxygen-containing gas into the slag holding furnace; causing the burned exhaust gas to flow from the slag holding furnace to a suction device through an exhaust gas pipe; adjusting an internal pressure of the electric furnace by introducing external air into the exhaust gas pipe through an opening portion provided in the middle of the exhaust gas pipe; and changing an area of the opening portion depending on a variation in the internal pressure of the electric furnace by using an opening area changing unit provided in the opening portion. | 2016-06-09 |
20160160304 | USE OF TOP GAS IN DIRECT REDUCTION PROCESSES - In one aspect, the invention relates to a system for producing direct reduced iron wherein a portion of the top gas from a first module for reducing iron oxide by a direct reduction process is utilized as fuel in the thermal equipment of a second module for reducing iron oxide by a direct reduction process, wherein the second module comprises a process gas heating unit. In various aspects, the thermal equipment of the second module is a reducing gas heater and/or a steam boiler. In a further aspect, the top gas from multiple instances of the first module can be utilized collectively as fuel in the thermal equipment of the second module. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 2016-06-09 |
20160160305 | METHOD OF FORMING GOLF CLUB HEAD ASSEMBLY - A method of forming a golf club head assembly includes aligning a faceplate with a recess of a club head; welding the faceplate to the club head; then, after welding the faceplate, heating the club head and the faceplate to at least a solvus temperature of the faceplate for a predetermined amount of time; and then, after heating the club head and the faceplate, allowing the club head and the faceplate to air cool. | 2016-06-09 |
20160160306 | COIL SPRING, AND METHOD FOR MANUFACTURING SAME - To provide a coil spring having excellent fatigue resistance. | 2016-06-09 |
20160160307 | LOW ALLOY OIL WELL STEEL PIPE AND METHOD FOR MANUFACTURING SAME - Low-alloy oil-well steel pipe includes a composition consisting, in mass %, of C: 0.40 to 0.65%, Si: 0.05 to 0.50%, Mn: 0.10 to 1.00%, P: 0.020% or less, S: 0.0020% or less, Cu: 0.15% or less, Cr: 0.40 to 1.50%, Mo: 0.50 to 2.50%, V: 0.05 to 0.25%, Ti: 0 to less than 0.01%, Nb: 0.01 to 0.2%, sol.Al: 0.010 to 0.100%, N: 0.006% or less, B: 0 to 0.0015%, and Ca: 0 to 0.003%, the balance being Fe and impurities. The structure has tempered martensite and 0 to less than 2% volume ratio of retained austenite. A grain size number of prior-austenite grain in the structure is 9.0 or more. An equivalent circular diameter of a sub-structure surrounded by a boundary having a crystal orientation difference of 15° or more from a packet boundary, a block boundary and a lath boundary is 3 μm or less for the tempered martensite. | 2016-06-09 |
20160160308 | STEEL SHEET FOR CAN AND METHOD FOR MANUFACTURING THE SAME - A steel sheet exhibiting good drawability and excellent buckling strength of a can body portion against an external pressure, and a method for manufacturing the same. The steel sheet includes C: 0.0030% or more and 0.0100% or less, Si: 0.05% or less, Mn: 0.10% or more and 1.0% or less, P: 0.030% or less, S: 0.020% or less, Al: 0.010% or more and 0.100% or less, N: 0.0050% or less, Nb: 0.010% or more and 0.050% or less, and incidental impurities. Contents of C and Nb satisfy 0.10 ([Nb]/92.9)/([C]/12)<0.60, the HR30T hardness of the steel sheet is 56 or more, and the average Young's modulus of the steel sheet is 210 GPa or more. | 2016-06-09 |
20160160309 | STEEL SHEET HAVING VERY HIGH MECHANICAL PROPERTIES OF STRENGTH AND DUCTILITY, MANUFACTURING METHOD AND USE OF SUCH SHEETS - The invention relates to the manufacture of a cold-rolled steel sheet having a strength of more than 900 MPa, an elastic limit of more than 700 MPa and distributed elongation of more than 12%, the composition of which includes, the contents being expressed as weight percentages: 0.26%≦C≦0.45%, 1.0%≦Mn≦3.0%, 1.0%≦Si≦3.0%, Al≦0.10%, 0%≦Cr≦1.5% %, S≦0.005%, P≦0.020%, Nb≦0.1%, Ti≦0.020%, V≦0.015%, N≦0.01%, the remainder of the composition being iron and inevitable impurities resulting from the production process. The microstructure, given in surface proportions, comprises 13% to 25% residual austenite and 13% to 30% MA islands, the remainder consisting of bainite and possibly ferrite. | 2016-06-09 |
20160160310 | HIGH-STRENGTH GALVANIZED STEEL SHEET HAVING EXCELLENT FORMABILITY AND CRASHWORTHINESS AND METHOD FOR MANUFACTURING THE SAME - A method of manufacturing a galvanized steel sheet having a composition containing, by mass %, C: 0.05% or more and 0.5% or less, Si: 0.01% or more and 2.5% or less, Mn: 0.5% or more and 3.5% or less, P: 0.003% or more and 0.100% or less, S: 0.02% or less, Al: 0.010% or more and 0.5% or less, B: 0.0002% or more and 0.005% or less, Ti: 0.05% or less, a relationship of Ti>4N being satisfied, and the balance comprising Fe and inevitable impurities, and a microstructure containing 60% or more and 95% or less of tempered martensite in terms of area ratio and 5% or more and 20% or less of retained austenite in terms of area ratio | 2016-06-09 |
20160160311 | METHOD FOR FORMING BLANK AND METHOD FOR DETERMINING PREFORMING SHAPE - By using, as a raw material, a thick hot-rolled steel sheet having a chemical composition containing, by mass %, C: 0.02% or more and 0.10% or less, Si: 0.05% or more and 0.30% or less, Mn: 0.80% or more and 2.00% or less, and Nb: 0.010% or more and 0.100% or less and satisfying the condition that a carbon equivalent Ceq is 0.25% or more and 0.50% or less, a microstructure including a bainitic ferrite phase and/or a bainite phase, a high strength of 52 ksi or more in terms of yield strength and a high toughness of −45° C. or lower in terms of fracture transition temperature vTrs, an electric resistance weld zone having a microstructure including a bainitic ferrite phase and/or a bainite phase and satisfying the condition that the ratio of the average crystal grain size of the coarsest-grain portion to the average crystal grain size of the finest-grain portion is 2.0 or less in every portion in the wall thickness direction is obtained. | 2016-06-09 |
20160160312 | Hydrometallurgical System and Process Using an Ion Transport Membrane - A hydrometallurgical system and process with a hydrometallurgical processing circuit integrated with an ion transport membrane assembly. The ion transport membrane assembly provide oxygen to the hydrometallurgical processing circuit. | 2016-06-09 |
20160160313 | PROCESSES FOR PRODUCING TANTALUM ALLOYS AND NIOBIUM ALLOYS - Processes for the production of tantalum alloys and niobium are disclosed. The processes use aluminothermic reactions to reduce tantalum pentoxide to tantalum metal or niobium pentoxide to niobium metal. | 2016-06-09 |
20160160314 | APPARATUS AND METHOD FOR SEQUENTIAL MELTING AND REFINING IN A CONTINUOUS PROCESS - An apparatus and a method performable with the apparatus for sequential melting and refining of materials are proposed. The materials treated in the process are converted to a liquid state of matter by heat sources. The process is particularly suitable for treating metals, semimetals and ceramics, for example in order to produce alloys and/or to refine the materials. During the method, the material goes through various treatment chambers which enable treatment at different pressure levels. | 2016-06-09 |
20160160315 | METHOD FOR RECYCLING LEAD OXIDE-CONTAINING WASTE MATERIAL - Provided is a method for recycling a lead oxide-containing waste material, comprising: (1) contacting the lead oxide-containing waste material with a desulphurizer under desulphurization reaction conditions, and performing a solid-liquid separation on the mixture after contacting to obtain a filtrate and a filtration residue; (2) performing a conversion reaction on the above-mentioned filtration residue at a temperature of 350-750° C. so as to convert the lead-containing components in the filtration residue into lead oxide; (3) contacting the product obtained from step (2) with an alkaline solution so as to dissolve the PbO therein, and then performing a solid-liquid separation to obtain a PbO-alkaline solution; and (4) crystallizing the PbO-alkaline solution from step (3) to obtain PbO crystals and an alkaline filtrate. The method can reduce the energy consumption. | 2016-06-09 |
20160160316 | METHOD FOR DIRECTLY RECOVERING LEAD OXIDE USED FOR A LEAD-ACID BATTERY CATHODE FROM WASTE LEAD PASTE - Provided is a method for directly recovering lead oxide used for a lead-acid battery negative electrode from waste lead paste. The method comprises: (1) contacting waste lead paste with a barium-containing desulphurizer under desulphurization reaction conditions, and performing a solid-liquid separation on the mixture after contacting to obtain a filtrate and a filtration residue; and (2) performing a conversion reaction on the above-mentioned filtration residue at a temperature of 350-750° C. so as to convert the lead-containing components in the filtration residue into lead oxide. In the method, the direct recovery of a lead oxide raw material applicable to a lead-acid battery negative electrode from waste lead paste is achieved by quantitatively replenishing a barium sulphate additive in the process of desulphuration thereby substantially decreasing the recovery cost and energy consumption, and improving the comprehensive utilization of waste lead paste. | 2016-06-09 |
20160160317 | METHOD AND SYSTEM FOR REMOVING SILICA FROM AN ORE - The present disclosure provides a beneficiation arrangement for removing silica from an ore. The beneficiation arrangement includes one or more scrubbing arrangements to scrub the ore with a stream of a washing fluid and recover the silica, one or more screening arrangements to perform screening of the scrubbed ore to extract a first quantity of recovered ore and an underflow, and one or more separating arrangements to enable separation of at least silica particles from the underflow. The one or more separating arrangements include one or more cyclonic separating arrangements to cyclonically separate the silica particles into one or more ranges of sizes of the silica particles from the underflow, and one or more filter press arrangements to perform pressure filtration on a recovered ore extract mix of the one or more recovered ore extract mix. | 2016-06-09 |
20160160318 | SYSTEM AND METHOD FOR ADDING MOLTEN LITHIUM TO A MOLTEN ALUMINIUM MELT - A system for adding molten lithium and inert gas in a molten aluminium or aluminium alloy melt including, a crucible defining a chamber for melting and storing molten metal, in particular molten lithium; the crucible having a sealed lid; an inert gas delivery system for maintaining chamber overpressure using inert gas; a conduit for withdrawing a portion of the molten metal from the crucible. The conduit arranged with respect to the crucible or the sealed lid so the conduit inlet can be moved below and above the molten metal surface level and arranged for feeding molten metal from the crucible to a separate holding furnace with the help of overpressure when the conduit inlet is below the molten metal surface level and arranged for feeding inert gas from the crucible to the separate holding furnace when the conduit inlet is above the molten metal surface level. | 2016-06-09 |