24th week of 2012 patent applcation highlights part 51 |
Patent application number | Title | Published |
20120149550 | CATALYST COMPOSITIONS FOR IMPROVED FLUID CATALYTIC CRACKING (FCC) PROCESSES TARGETING PROPYLENE PRODUCTION - Catalyst compositions comprising a siliceous zeolite component, either in separately formed catalyst particles or dispersed in the same binder or matrix as other zeolites of the compositions, are described. The catalyst compositions, for example as blends of three different bound zeolite catalysts, are particularly useful in fluid catalytic cracking (FCC) processes due to the reductions in coke and dry gas yields that allow FCC throughput, which is normally constrained by gas handling and/or catalyst regeneration capacity, to be increased. | 2012-06-14 |
20120149551 | TWO-LAYER CATALYST, PROCESS FOR PREPARING SAME AND USE FOR THE MANUFACTURE OF NANOTUBES - A catalyst material for preparing nanotubes, especially carbon nanotubes, said material being in the form of solid particles, said particles including a porous substrate supporting two superposed catalytic layers, a first layer, directly positioned on the substrate, including at least one transition metal from column VIB of the Periodic Table, preferably molybdenum, and a second catalytic layer, positioned on the first layer, comprising iron. Also, a process for preparing same and to a process for the synthesis of nanotubes using this catalyst material. | 2012-06-14 |
20120149552 | Processes For Making Multimodal Molecular Weight Distribution Polyolefins - This invention relates to a process to make a multimodal polyolefin composition comprising: (i) contacting at least one first olefin monomer with a mixed catalyst system, under polymerization conditions, to produce at least a first polyolefin component having a Mw of 5,000 g/mol to 600,000 g/mol, wherein the mixed catalyst system comprises: (a) at least one polymerization catalyst comprising a Group 4 or Group 5 transition metal; (b) at least one organochromium polymerization catalyst; (c) an activator; and (d) a support material; (ii) thereafter, contacting the first polyolefin component/mixed catalyst system combination with a molecular switch; (iii) contacting the first polyolefin component/mixed catalyst system combination with at least one second olefin monomer, which may be the same or different, under polymerization conditions; and (iv) obtaining a multimodal polyolefin composition. | 2012-06-14 |
20120149553 | CONCENTRATED SOLUTIONS OF ALKALINE-EARTH METAL OXIDES IN APROTIC SOLVENTS AND METHOD FOR THE PRODUCTION THEREOF - A concentrated solution of mixed alkaline-earth alkoxide compounds M(OCH | 2012-06-14 |
20120149554 | GRAPHENE/NANO-TITANIUM DIOXIDE COMPOSITES AND METHODS FOR PREPARING THE SAME - Disclosed herein are methods for preparing graphene/nano-titanium dioxide composites. About 500 to 10,000 parts by weight of nano-titanium dioxide and about 1 part by weight of graphene are distributed in a water-ethanol (about 2:1 to 3:1 by volume) solution to obtain a dispersion. The nano-titanium dioxide and graphene within the dispersion are allowed to react under a pressure of about 10 to 15 MPa and a temperature of about 100 to 200° C. thereby producing the graphene/nano-titanium dioxide composites. | 2012-06-14 |
20120149555 | Method for Producing Alloy Catalyst for Redox Reaction - A method for producing an alloy catalyst for redox reaction comprising alloy particles of platinum and nickel, wherein the alloy particles are equipped at an outer surface with a crystal lattice plane represented by a Miller index {111} and have an average particle diameter in a range of 6 to 20 nm, the method comprising: dissolving, in an alcohol, a salt and/or complex of platinum, a salt and/or complex of nickel, and a polymer containing a plurality of salt structures comprising an organic cation and a halogen anion in a polymer chain and heating the resulting solution to reflux under an inert atmosphere. | 2012-06-14 |
20120149556 | PHOTOCATALYTIC MATERIAL - One subject of the invention is a material comprising a substrate coated on at least one portion of at least one of its faces with a stack comprising a photocatalytic layer, the geometrical thickness of which is between 2 and 30 nm, and at least one pair of respectively high and low refractive index layers positioned underneath said photocatalytic layer so that in the or each pair, the or each high refractive index layer is closest to the substrate, said material being such that the optical thickness, for a wavelength of 350 nm, of the or each high refractive index layer, except the photocatalytic layer, is between 170 and 300 nm and the optical thickness, for a wavelength of 350 nm, of the or each low refractive index layer is between 30 and 90 nm. | 2012-06-14 |
20120149557 | EXHAUST GAS-PURIFYING CATALYST - An exhaust gas-purifying catalyst includes first particles of oxygen storage material, second particles of one or more alkaline-earth metal elements and/or compounds thereof interposed between the first particles, and third particles of one or more precious metal elements interposed between the first particles. A spectrum of a first characteristic X-ray intensity for one of the one or more alkaline-earth metal elements and a spectrum of a second characteristic X-ray intensity for one of the one or more precious metal elements that are obtained by performing a line analysis using energy-dispersive X-ray spectrometry along a length of 500 nm have a correlation coefficient σ(AE,PM) of 0.70 or more. | 2012-06-14 |
20120149558 | Catalyst for hydrodechlorination of chlorosilanes to hydrogen silanes and method for implementing hydrogen silanes using said catalyst - The invention relates to a method for producing hydrogen silanes of general formula R | 2012-06-14 |
20120149559 | EGGSHELL CATALYST AND METHODS OF ITS PREPARATION - An eggshell catalyst useful for a Fischer-Tropsch (FT) synthesis or other reactions comprises a homogeneously dispersed transition metal and a promoter situated in an active phase in a precisely selected outer region of a catalyst pellet. The active phase region is controlled to a specific depth, which permits the control of the catalysts selectivity, for example, the size of the hydrocarbon chains formed in the FT process. A method of preparing these eggshell catalysts involves a non-aqueous synthesis where polar and non-polar solvents of relatively low vapor pressure are employed to define the depth of penetration of metal species in a refractory oxide substrate, which is followed by fixing and activating metallic catalytic species in the structure by calcination of the catalyst particles. | 2012-06-14 |
20120149560 | METHOD OF MANUFACTURING POROUS METAL OXIDE - Provided is a method of manufacturing porous metal oxide, the method including: preparing a metal-organic framework (MOF) wherein an ion of a metal to be used as a catalyst is linked to an organic ligand; impregnating the MOF with a precursor solution of metal oxide to be manufactured; and thermally treating the metal oxide precursor solution-impregnated MOF to remove the organic ligand. The inventive method of manufacturing porous metal oxide involves the impregnation of a metal oxide precursor solution in a MOF wherein metal ions are uniformly linked to organic ligands and the thermal treatment (calcination) of the metal oxide precursor solution-impregnated MOF to remove the organic ligands. | 2012-06-14 |
20120149561 | ON-DEMAND PRINTABLE CONSTRUCT - Multi-ply thermally printable constructs include a thermal print medium sandwiched between two opaque substrates that are temporarily bonded together to prevent information that is thermally printed through one of the substrates from being viewed until the substrates are separated. The thermal print medium, opaque substrates, and the means for bonding the substrates can take various forms for achieving particular objectives. | 2012-06-14 |
20120149562 | DECOLORING APPARATUS AND CONTROL METHOD FOR DECOLORING APPARATUS - According to one embodiment, first and second branch paths of a decoloring apparatus are formed downstream in a sheet conveying direction of a reading section in a conveying path. A diverting section is provided at a branch point of the first and second branch paths in the conveying path. A control section determines on the basis of image data whether decoloring processing should be applied to a sheet, diverts, if determining that the decoloring processing should be applied to the sheet, the sheet to the first branch path with the diverting section, and diverts, if determining that the decoloring processing should not be applied to the sheet, the sheet to the second branch path with the diverting section. A decoloring section is provided between the reading section and the branch point in the conveying path and heats the sheet to decolor an image formed with a decolorable color material. | 2012-06-14 |
20120149563 | ACRYLATE/METHACRYLATE-BASED RANDOM COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING - Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition:
| 2012-06-14 |
20120149564 | ANTHRANILIC DIAMIDE AND CYCLODEXTRIN COMPOSITIONS FOR PROPAGULE COATING - Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition:
| 2012-06-14 |
20120149565 | ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGLE COATING - Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition:
| 2012-06-14 |
20120149566 | ACRYLATE/METHACRYLATE-BASED DIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING - Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition:
| 2012-06-14 |
20120149567 | ACRYLATE/METHACRYLATE-BASED STAR COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGLE COATING - Disclosed is an insecticidal composition comprising by weight based on the total weight of the composition:
| 2012-06-14 |
20120149568 | COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES - The present invention provides: a composition for controlling plant diseases comprising, as active ingredients, 4-oxo-4-[(2-phenylethyl)amino]-butyric acid and ethaboxam; a method for controlling plant diseases which comprises applying effective amounts of 4-oxo-4-[(2-phenylethyl)amino]-butyric acid and ethaboxam to a plant or soil for growing plant; and so on. | 2012-06-14 |
20120149569 | Mitigating Necrosis in Transgenic Glyphosate-Tolerant Cotton Plants Treated with Herbicidal Glyphosate Formulations - This invention relates generally to improved methods and herbicidal glyphosate compositions for use in controlling the growth of weeds and unwanted vegetation, and particularly for use in controlling weeds in a crop of transgenic glyphosate-tolerant cotton plants by over-the-top, foliar application of a herbicidal glyphosate formulation. | 2012-06-14 |
20120149570 | Foamable Pesticide Compositions And Methods Of Application - Ready-to-use foamable pesticide compositions that contain a pesticide dispersed in a composition containing water, a co-solvent, surfactant and propellant. Methods for treating pests such as arthropods by contacting pests with such compositions are also provided. | 2012-06-14 |
20120149571 | Inoculants Including Bacillus Bacteria for Inducing Production of Volatile Organic Compounds in Plants - Disclosed are inoculants that include | 2012-06-14 |
20120149572 | USE OF AGROCHEMICAL MIXTURES FOR INCREASING THE HEALTH OF A PLANT - The present invention relates to the use of a mixture comprising, as active compounds 1) a herbicide (compound I) selected from the group of synthetic auxins consisting of (i) Phenoxy-carboxylic-acids selected from clomeprop, 2,4-D, 2,4-DB, dichlorprop, MCPA, MCPB and mecoprop; (ii) Benzoic acids selected from chloramben, dicamba and 2,3,6-TBA; (iii) Pyridine carboxylic acids selected from aminopyralid, clopyralid, fluoroxypyr, picloram and triclopyr; (iv) Quinoline carboxylic acids selected from quinclorac and quinmerac; (v) benazolin-ethyl; and (vi) amino-cylopyrachlor; and 2) a fungicide (compound II) selected from the group of strobilurines consisting of pyraclostrobin, orysastrobin, azoxystrobin, dimoxystrobin, enestroburin, fluoxastrobin, kresoxim-methyl, metominostrobin, picoxystrobin, pyribencarb, trifloxystrobin, 2-(2-(6-(3-chloro-2-methyl-phenoxy)-5-fluoro-pyrimidin-4-yloxy)-phenyl)-2-methoxyimino-N-methyl-acetamide, 3-methoxy-2-(2-(N-(4-methoxy-phenyl)-cyclopropane-carboximidoylsulfanylmethyl)-phenyl)-acrylic acid methyl ester, methyl (2-chloro-5-[1-(3-methylbenzyloxyimino)-ethyl]benzyl)carbamate and 2-(2-(3-(2,6-dichlorophenyl)-1-methyl-allylideneaminooxymethyl)-phenyl)-2-methoxyimino-N-methyl-acetamide; for synergistically increasing the health of a plant. In addition, the invention relates to respective mixtures for increasing the health of a plant. | 2012-06-14 |
20120149573 | HERBICIDAL BUS-NITROGEN-CONTAINING OXO AND SULFONO HETEROCYCLES - Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, | 2012-06-14 |
20120149574 | Methods and Compositions for Managing Water Quality in a Body of Water - Described are compositions and methods for application to a body of water to manage water quality therein. The compositions and methods involve the use of a combination of aluminum sulfate and copper sulfate formulated for rapid release in the body of water. Simple compositions and facile methods are made available which balance algae control and phosphorous depletion to improve or maintain water quality while not unduly upsetting other chemistries of the body of water. | 2012-06-14 |
20120149575 | A-87774 COMPOUNDS OR SALTS THEREOF, PRODUCTION METHOD THEREOF AND AGROCHEMICALS CONTAINING THE SAME AS ACTIVE INGREDIENT - There are provided novel A-87774 compounds or salts thereof having a herbicidal activity or a plant growth regulating activity, a microorganism producing the same, a production method thereof, an agrochemical (in particular, herbicide or plant growth regulator) containing the same as an active ingredient, a method for using the same, and a culture of the microorganism. | 2012-06-14 |
20120149576 | METHOD FOR CULTIVATING CROP PLANT - The present invention enables providing a method for cultivating a crop plant into which has been introduced either one or both of (1) DNA comprising a nucleotide sequence encoding the amino acid sequence of a cytochrome P450 that shows saflufenacil metabolizing activity and (2) DNA comprising a nucleotide sequence encoding the amino acid sequence of a protein that shows protoporphyrinogen IX oxidase activity, wherein said method comprises applying a weed control agent that contains saflufenacil as an active ingredient to an area where said crop plant is cultivated; among others. | 2012-06-14 |
20120149577 | Aqueous Suspension Concentrate Formulations Containing Saflufenacil - The present invention relates to aqueous suspension concentrate formulation for plant protection comprising:
| 2012-06-14 |
20120149578 | Manipulation of Cloud Point for Two-Phase, Aqueous Polymeric Systems - Two-phase, aqueous polymeric systems comprised of lactamic monomers containing additives suitable for adjusting the cloud point temperature of the polymeric compositions are described. Of particular utility is the use of these additives to adjust the cloud point in aqueous solutions comprised of salts. | 2012-06-14 |
20120149579 | Precursor for a Nb3Sn superconductor wire, method for manufacturing the same, Nb3Sn superconductor wire, and superconducting magnet system - A precursor for a Nb | 2012-06-14 |
20120149580 | Method of Manufacturing a Solenoidal Magnet, and a Solenoidal Magnet Structure - A method of manufacturing a solenoidal magnet structure, comprising the steps of providing a collapsible mold in which to wind coils; winding wire into defined positions ( | 2012-06-14 |
20120149581 | Process of constructing oxidation-reduction nanomedicine quantum dots room temperature quantum bit networks - Preparation of oxidation-reduction (redox) nano-medicine quantum dot room temperature superconductor quantum bit (qubit) networks includes processes of making unitary, binary, ternary, and/or quaternary liquid pharmaceutical ingredients of an antioxidase antioxidant, a β-adrenergic receptor agonist, a P | 2012-06-14 |
20120149582 | METHOD FOR DETERMINING COPY NUMBER VARIATIONS - The invention provides a method for determining copy number variations (CNV) of a sequence of interest in a test sample that comprises a mixture of nucleic acids that are known or are suspected to differ in the amount of one or more sequence of interest. The method comprises a statistical approach that accounts for accrued variability stemming from process-related, interchromosomal and inter-sequencing variability. The method is applicable to determining CNV of any fetal aneuploidy, and CNVs known or suspected to be associated with a variety of medical conditions. CNV that can be determined according to the present method include trisomies and monosomies of any one or more of chromosomes 1-22, X and Y, other chromosomal polysomies, and deletions and/or duplications of segments of any one or more of the chromosomes, which can be detected by sequencing only once the nucleic acids of a test sample. | 2012-06-14 |
20120149583 | METHOD FOR DETERMINING COPY NUMBER VARIATIONS - The invention provides a method for determining copy number variations (CNV) of a sequence of interest in a test sample that comprises a mixture of nucleic acids that are known or are suspected to differ in the amount of one or more sequence of interest. The method comprises a statistical approach that accounts for accrued variability stemming from process-related, interchromosomal and inter-sequencing variability. The method is applicable to determining CNV of any fetal aneuploidy, and CNVs known or suspected to be associated with a variety of medical conditions. CNV that can be determined according to the present method include trisomies and monosomies of any one or more of chromosomes 1-22, X and Y, other chromosomal polysomies, and deletions and/or duplications of segments of any one or more of the chromosomes, which can be detected by sequencing only once the nucleic acids of a test sample. | 2012-06-14 |
20120149584 | METHODS OF DIAGNOSING AND TREATING MICROBIOME-ASSOCIATED DISEASE USING INTERACTION NETWORK PARAMETERS - Methods of diagnosing and treating microbiome-associated disease or improving health using interaction network parameters are provided. Methods are provided to analyze interaction networks between microbes, and between microbes and the host, to determine important (e.g. “highly-connected”) organisms or molecules as determined by various network parameters. Methods are provided including and beyond correlation to use these “highly-connected” organisms or molecules as targets for modulation or as therapeutic agents to improve health. | 2012-06-14 |
20120149585 | COMPENSATOR FOR MULTIPLE SURFACE IMAGING - A system and method for imaging biological samples on multiple surfaces of a support structure are disclosed. The support structure may be a flow cell through which a reagent fluid is allowed to flow and interact with the biological samples. Excitation radiation from at least one radiation source may be used to excite the biological samples on multiple surfaces. In this manner, fluorescent emission radiation may be generated from the biological samples and subsequently captured and detected by detection optics and at least one detector. The detected fluorescent emission radiation may then be used to generate image data. This imaging of multiple surfaces may be accomplished either sequentially or simultaneously. In addition, the techniques of the present invention may be used with any type of imaging system. For instance, both epifluorescent and total internal reflection methods may benefit from the techniques of the present invention. | 2012-06-14 |
20120149586 | METHODS OF PREDICTING THE RISK OF RECURRENCE OF CANCER - Disclosed herein are methods of predicting the risk of recurrence of cancer on the basis of the expression of microRNA of the miR-520 family. | 2012-06-14 |
20120149587 | METHOD FOR DETECTING NUCLEATED CELLS - The invention provides methods to detect or quantify cells such as nucleated cells in a sample such as a physiological sample, which employ magnetic substrates and subjects the sample and the magnetic substrate to forms of energy so as to induce aggregate formation. | 2012-06-14 |
20120149588 | Phased Genome Sequencing - The present disclosure provides methods for determining phased nucleic acid sequence for a single chromosome of interest and/or a single chromosomal fragment of interest. The present disclosure also provides methods for determining phased nucleic acid sequence for a plurality of single chromosomes of interest and/or a plurality of single chromosomal fragments of interest. The plurality of single chromosomes of interest may be of one or more chromosome types. The present disclosure also provides a method for isolating a plurality of chromosomal fragments of a specified size range, where the chromosomal fragments are from one or more specified regions of the genome. The plurality of chromosomal fragments may be separated into single chromosomal fragments and sequenced to provide phased nucleic acid sequence for the single chromosomal fragments. Alternatively, the plurality of chromosomal fragments may be sequenced together to provide unphased nucleic acid sequence for the chromosomal fragments. | 2012-06-14 |
20120149589 | Epigentic Markers Associated with Substance Use Disorders - DNA methylations markers are associated with brain and behavioral mechanisms that underlie substance abuse disorders. These methylation markers present novel measures for predicting and/or identifying effective treatment options, risk of cancer development, risk of developing substance abuse disorders, and substance-abuse related behaviors such as binge drinking. These markers may further be useful in developing novel pharmaceuticals and treatment methodologies and provide mechanisms for following the course of an individual's treatment, risks, or behaviors over time. | 2012-06-14 |
20120149590 | LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING CELL SURFACE PROTEIN HOMOLOGUES AND USES THEREFORE - Cell wall, cell surface and secreted protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, cell wall, cell surface and secreted fusion proteins, antigenic peptides, and anti-cell wall, cell surface and secreted antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and host cells into which the expression vectors have been introduced. Methods for producing the polypeptides of the invention and methods for their use are further disclosed. | 2012-06-14 |
20120149591 | IN VITRO PEPTIDE EXPRESSION LIBRARY - The invention provides a method for making in vitro peptide expression libraries, and for the isolation of nucleotide sequences encoding peptides of interest, wherein the peptides or proteins are specifically associated with the DNA encoding them through non-covalent protein:DNA binding. The method describes ways of making the library itself, DNA molecules encoding the library and uses of the expression library. | 2012-06-14 |
20120149592 | Compositions And Methods For Assessing Cytotoxicity Of Single Cells - The invention provides a method of analyzing interactions between pairs of target and effector cells utilizing high-throughput screenings methods for profiling large numbers of single cells in microarrays. | 2012-06-14 |
20120149593 | METHODS AND ARRAYS FOR PROFILING DNA METHYLATION - This invention provides methods and arrays for determination of the methylation patterns at single-nucleotide resolution by array-based hybrid selection and next-generation sequencing of bisulfite-treated DNA. | 2012-06-14 |
20120149594 | BIOMARKERS FOR PREDICTION OF BREAST CANCER - The invention provides gene expression profiles (GEPs), protein expression profiles (PEPs) as well as gene/protein expression profiles (GPEPs) and methods for using them to identify those patients who are likely to progress to breast cancer after detection of suspicious calcifications and/or fibrocystic disease by standard imaging techniques, e.g., mammography, MRI or ultrasound. The present invention further allows a treatment provider to identify those patients who are most likely to develop breast cancer to initiate and/or adjust treatment options for such patients accordingly. | 2012-06-14 |
20120149595 | MARKERS FOR DIAGNOSIS OF PULMONARY INFLAMMATION AND METHODS RELATED THERETO - The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163. | 2012-06-14 |
20120149596 | METHODS FOR ASSESSING ATHEROGENESIS BY DETERMINING OXIDIZED PHOSPHOLIPID TO APOLIPOPROTEIN B RATIOS - The present invention relates to the analysis of oxidized phospholipids (OxPL) on apolipoprotein B-100 in patients at high risk or with documented coronary artery disease (CAD) or acute coronary syndromes (ACS) such as unstable angina and acute myocardial infarction or suspected of being at risk for ACS. Such methods are useful for diagnostic purposes and for monitoring the effects of dietary interventions or with drugs such as statins. More particularly, the present invention relates to methods for determining OxPL/apoB ratios as indices of atherosclerosis regression and plaque stability. | 2012-06-14 |
20120149597 | Protein fragment complementation assays for high-throughput and high-content screening - The present invention provides protein fragment complementation assays for drug discovery, in particular to identify compounds that activate or inhibit cellular pathways. Based on the selection of an interacting protein pair combined with an appropriate PCA reporter, the assays may be run in high-throughput or high-content mode and may be used in automated screening of libraries of compounds. The interacting pair may be selected by cDNA library screening; by gene-by-gene interaction mapping; or by prior knowledge of a pathway. Fluorescent and luminescent assays can be constructed using the methods provided herein. The selection of suitable PCA reporters for high-throughput or high-content (high-context) assay formats is described for a diversity of reporters, with particular detail provided for examples of monomeric enzymes and fluorescent proteins. Methods are described for constructing such assays for one or more steps in a biochemical pathway; testing the effects of compounds from combinatorial, natural product, peptide, antibody, nucleic acid or other diverse libraries on the protein or pathway(s) of interest; and using the results of the screening to identify specific compounds that activate or inhibit the protein or pathway(s) of interest. Single-color and multi-color assays are disclosed. Further disclosed are universal expression vectors with cassettes that allow the rapid construction of assays for a large and diverse number of gene/reporter combinations. The development of such assays is shown to be straightforward, providing for a broad, flexible and biologically relevant platform for drug discovery. | 2012-06-14 |
20120149598 | FEEDER CELLS FOR TARGET CELL INDUCTION - The present invention provides a feeder cell for target cell induction, wherein the feeder cell is transduced with an immortalizing gene and a suicide gene; and a production process for a target cell sheet using the feeder cell for target cell induction. | 2012-06-14 |
20120149599 | COMBINED RAPID SUSCEPTIBILITY ASSAY AND MICROORGANISM IDENTIFICATION SYSTEM - In response to the need for highly-sensitive antibiotic susceptibility assays and identification assays that do not require extensive incubation times, the present invention provides automated assay methods and systems that permit the determination of antibiotic susceptibilities and/or microorganism identification in a timeframe that is substantially shorter than has previously been attainable using a hybrid system that combines turbimetric and fluorescence determinations using a single, clear-plastic assay platform. Related devices, kits, and components thereof are also disclosed. | 2012-06-14 |
20120149600 | MICROFLUIDIC DEVICES AND METHODS - Contemplated microfluidic devices and methods are drawn to protein arrays in which distinct and detergent-containing antigen preparations are deposited onto an optical contrast layer in a non-specific and non-covalent manner. Detection of binding a is carried out using a dye that precipitates or agglomerates to so form a visually detectable signal at a dynamic range of at least three orders of magnitude. | 2012-06-14 |
20120149601 | Methods and systems for detection of nitroalkyl, nitroamine, nitroaromatic and peroxide compounds - Methods, systems and related apparatus for fluorescence-based detection of various nitro and peroxide compounds. | 2012-06-14 |
20120149602 | METHOD FOR MAKING POPULATIONS OF DEFINED NUCLEIC ACID MOLECULES - The present invention provides methods of making a population of nucleic acid molecules, wherein each nucleic acid molecule comprises a predetermined nucleic acid sequence, each of said methods comprising the steps of: (a) synthesizing, on a substrate, a population of nucleic acid molecules wherein: i) each synthesized nucleic acid molecule comprises a predetermined nucleic acid sequence; and ii) each synthesized nucleic acid molecule is localized to a defined area of said substrate; (b) harvesting said population of synthesized nucleic acid molecules from said substrate to yield harvested nucleic acid molecules; and (c) introducing said harvested nucleic acid molecules into vector molecules. | 2012-06-14 |
20120149603 | SAMPLE ANALYSIS SYSTEM - An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber. | 2012-06-14 |
20120149604 | Chemical Scavenger For Downhole Chemical Analysis - A method for analyzing formation fluid in a subterranean formation is disclosed, wherein the method includes the steps of: adding a scavenger compound to an analytical reagent to form a reagent solution; collecting an amount of formation fluid into a formation tester, wherein the formation tester includes at least one fluids analyzer comprising at least one probe, at least one flow line, at least one reagent container, and at least one spectral analyzer, wherein the fluids analyzer is configured such that the collected formation fluid is fed through the at least one flow line to the at least one spectral analyzer; mixing an amount of the collected formation fluid with an amount of the reagent solution to form a mixture; and analyzing the mixture downhole. | 2012-06-14 |
20120149605 | Composition and Method For Using Waxy Oil-External Emulsions To Modify Reservoir Permeability Profiles - A waxy oil-external emulsion is provided for injection into a selected zone of a subsurface formation. The selected zone is typically a high permeability zone. The emulsion generally comprises oil, added wax, and water. The emulsion may also include an emulsifying agent and a solvent. The emulsion is formulated to be a liquid at a temperature greater than a targeted temperature in the subsurface formation, but a solid at the targeted temperature. The targeted temperature is typically the maximum operating temperature for the formation. A method of formulating the emulsion is also provided. Further, a method of plugging a high permeability zone using the emulsion is disclosed. | 2012-06-14 |
20120149606 | System, Method And Apparatus For Enhancing Wellbore Treatment Fluid Flexibility - A method includes performing a chemical process to create a chemical product and an amount of heat, and transferring the heat to a first fluid. The method further includes hydrating a polymer in the first fluid, and adding the chemical product from the chemical process to the first fluid to create a treatment fluid. The method further includes diluting the treatment fluid with respect to at least one constituent of the treatment fluid. The method includes treating a formation of interest in a wellbore with the treatment fluid. The method includes changing a formulation of the treatment fluid during the treating. The method also includes extending the treating beyond a design amount, or ending the treatment before the design amount and preserving some reagents of the chemical process. | 2012-06-14 |
20120149607 | Method for Preventing Calcium Citrate Precipitation During Citric Acid Acidizing Treatments - Methods of preventing precipitation of calcium citrate and iron-based scale during acidizing treatments and related compositions are provided as embodiments of the present invention. The acidizing treatment fluid includes citric acid and tetra-salts of EDTA. | 2012-06-14 |
20120149608 | CORROSION INHIBITORS FOR OIL AND GAS APPLICATIONS - A corrosion inhibitor composition and method of inhibiting corrosion on a surface in an oil or gas application is disclosed and claimed. The corrosion inhibitor includes at least one fatty acid; at least one alkanolamine; at least one alkylamine; and at least one organic sulfonic acid. The method of inhibiting corrosion includes on a surface in an oil or gas application comprises contacting an effective dosage of the corrosion inhibitor with the surface. | 2012-06-14 |
20120149609 | POLYEPIHALOHYDRIN REVERSE EMULSION BREAKERS - A composition and method for resolving reverse emulsions and complex water external emulsions using one or more polyepihalohydrins, one or more polyelectrolytes thereof, and any combination thereof is disclosed and claimed. The disclosed invention may be used in any crude oil production process where such emulsions are encountered. | 2012-06-14 |
20120149610 | MULTIPLE COMPONENT NEUTRALLY BUOYANT PROPPANT - Proppant used to keep open a fissure in a reservoir created by hydraulic or other action is disclosed. The proppant demonstrates a reduced specific gravity controlled by the geometry of the structure of the proppant. Proppant must be capable of withstanding the hydrostatic environment of the hydraulic pumping system, pass through a perforation in the casing of the well, travel into the fissure, and, upon reduction of hydrostatic pressure, withstand the closure pressure of the formation. A proppant having neutral buoyancy or substantial neutral buoyancy yet capable of withstanding the hydraulic and closure pressures is described that has a tubular structure hollow in the center with a wall of material sufficiently strong to withstand the majority of closure pressures. | 2012-06-14 |
20120149611 | Coating Composition For Sliding Members - A coating composition for a sliding member, wherein from 30 to 120 parts by weight of a solid lubricant and from 5 to 80 parts by weight of a silicone resin are included per 100 parts by weight of a film-forming organic resin. As a result of forming the film on the surface of the sliding member, a coating composition for a sliding member is provided whereby low frictional drag can be maintained for an extended period of time, and the sticking of the sliding member to glass surfaces and similar smooth surfaces can be prevented. | 2012-06-14 |
20120149612 | PROCESS TO MAKE BASE OIL BY OLIGOMERIZING LOW BOILING OLEFINS - A process for making base oil, comprising: oligomerizing one or more olefins having a boiling point less than 82° C. in the presence of an ionic liquid catalyst to produce the base oil having a kinematic viscosity at 40° C. of 1100 mm | 2012-06-14 |
20120149613 | GREASE COMPOSITION AND METHODS FOR MANUFACTURING THE GREASE COMPOSITION - The present invention relates to a non-hydroxide grease composition comprising a base oil and a thickener which comprises amorphous hydrophilic silicon oxide particles and one or more metal salts of different organic acids, wherein the silicon oxide particles have a BET specific surface area of at least 50 m | 2012-06-14 |
20120149614 | Grease, rolling bearing, constant velocity joint, and rolling parts - The present invention provides grease which prevents frictional wear on a lubricating surface and excellent in performance of preventing occurrence of flaking, heat-resistant performance, and long-term durability, a grease-enclosed rolling bearing, a constant velocity joint, and rolling parts. Grease is composed of base grease, essentially containing a thickener, to which at least 0.01 to 15 wt % of one substance selected from among bismuth and inorganic bismuth compounds is added. The inorganic bismuth compounds are at least one inorganic bismuth selected from among bismuth sulfate, bismuth trioxide, bismuth carbonate, and sodium bismuthate. The above-described grease is used for the rolling bearing and the constant velocity joint. A coating film of at least one substance selected from among the bismuth and the inorganic bismuth is formed on surfaces of the rolling parts. | 2012-06-14 |
20120149615 | Strong Base Amines to Minimize Corrosion in Systems Prone to Form Corrosive Salts - Corrosion by ammonia/amine salts in hydrocarbon streams such as distillation overhead streams that contain a mineral acid and water can be prevented, avoided or minimized by adding certain strong amines to the streams. The amines have a pKa between about 10.5 to about 12 and include, but are not necessarily limited to, dimethylamine, diethylamine, dipropylamine, diisopropyl-amine, di-n-butylamine, diisobutylamine, di-sec-butylamine, di-tert-butylamine, pyrrolidine, piperidine, and combinations thereof. If the hydrocarbon stream further includes a nitrogen-containing compound such as ammonia, a tramp and/or a residual amine which can form a corrosive salt with the mineral acid, then the added amine is a stronger base than the tramp or residual amine, if present. The amount of added amine is greater than total amount of nitrogen-containing compound, so that any corrosive salts formed are less corrosive than the salts that would otherwise form from the ammonia and/or tramp amine. | 2012-06-14 |
20120149616 | WATER-BASED LUBRICANTS - Water-based lubricants for the lubrication of frictional partners in drive elements, as well as their use. In particular, a water-based lubricant that contains 5 to 80% by weight of water-soluble polyalkylene glycol that is selected from the group that is composed of statistically distributed polyoxyethylene units and/or polyoxypropylene units and/or other polyoxyalkylene components, a block polymer that that is composed of polyoxyethylene units and/or polyoxypropylene units and/or other polyoxyalkylene components, 0.5 to 20% by weight of foaming or non-foaming emulsifiers from the class of anionic, non-ionic, or cationic surfactants, water-soluble or water-emulsifiable carboxylic acid esters, 0.5 to 50% by weight of anti-icing additives, selected from the group that is composed of alkylene glycol, glycerol, salts or ionic liquids, 0.05 to 10% by weight of corrosion additives, 0.001 to 1% by weight of additives for preventing the formation of foam, and 0.05 to 5% by weight of friction-reducing agents and water added to make 100% by weight. | 2012-06-14 |
20120149617 | POLYTETRAHYDROBENZOXAZINES AND BISTETRAHYDROBENZOXAZINES AND USE THEREOF AS A FUEL ADDITIVE OR LUBRICANT ADDITIVE - Polytetrahydrobenzoxazines and bistetrahydrobenzoxazines, obtainable by (A) reacting at least one diamine of the formula H | 2012-06-14 |
20120149618 | Method for improving fluorocarbon elastomer seal compatibility - Disclosed is a method for improving compatibility of a fluorocarbon elastomer seal with a lubricating oil composition containing (a) a major amount of a base oil of lubricating viscosity; and (b) one or more dispersants containing one or more basic nitrogen atoms. The method involves adding to the lubricating oil composition an effective amount of one or more fluorocarbon elastomer compatibility improving agents comprising one or more non-halogen-containing oil-soluble titanium complexes comprising at least one ligand selected from the group consisting of (i) an anion of a saturated carboxylic acid, (ii) an anion of an α-, β- or γ-hydroxycarbonyl compound; (iii) an anion of an α-, β- or γ-hydroxycarboxylic acid, amide, or ester; (iv) an anion of an α-, β- or γ-aminocarboxylic acid; and (v) an anion of an α-, β- or γ-keto acid. | 2012-06-14 |
20120149619 | LUBRICANT COMPOSITION AND CONTINUOUSLY-VARIABLE TRANSMISSION - A lubricating oil composition is provided by mixing a lubricant base oil with components (A) to (C) as follows:
| 2012-06-14 |
20120149620 | GLYCOL ETHER-BASED CYCLOHEXANOATE ESTERS, THEIR SYNTHESIS AND METHODS OF USE - Glycol ether-based cyclohexanoate esters, their synthesis and methods of use as lubricant basestocks or co-basestocks. | 2012-06-14 |
20120149621 | LIQUID MIXTURE TO CLEAN DIELECTRIC BARRIER DISCHARGE SURFACES - Disclosed is a liquid cleaning mixture used to remove DMSO and other solvents and compounds that may build up on the surface of dielectric barrier material in a plasma cleaning device, where the DMSO, solvent and compounds have become contaminants. | 2012-06-14 |
20120149622 | PHOTORESIST STRIPPING AGENT COMPOSITION - Disclosed is a stripping agent that can easily strip a photoresist residue and the like at a low temperature in a short time and, at the same time, does not corrode a wiring material at all and has no need to use an organic solvent such as alcohol as a rinsing liquid. The stripping agent disclosed herein comprises 5 to 50% by mass of a specific amine, 30 to 65% by mass of a specific acid amide, 0.1 to 15% by mass of a saccharide or a sugar alcohol, and 1 to 64.5% by mass of water. | 2012-06-14 |
20120149623 | SOIL RESISTANT FLOOR CLEANER - A cleaning composition includes a fatty acid salt constituting up to about 50% by weight of the composition, an anti-slip agent constituting up to about 20% by weight of the composition, a soil resistant agent constituting up to about 20% by weight of the composition and water. Methods of cleaning coated and uncoated surfaces, and particularly stone surfaces, are also provided. | 2012-06-14 |
20120149624 | Subtilase Variants - The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. | 2012-06-14 |
20120149625 | Detergent Composition - The addition of a protease inhibitor to a particulate protease-containing detergent composition can improve its detergency and the inhibitor can improve the in-wash stability of the protease in a solution of the detergent. | 2012-06-14 |
20120149626 | Dibasic esters utilized as terpene co-solvents, substitutes and/or carriers in tar sand/bitumen/asphaltene cleaning applications - A heavy oil cleaning composition comprising: a) a blend of dibasic esters comprising dialkyl methylglutarate and at least one of a dialkyl adipate or dialkyl ethylsuccinate; b) at least one terpene; and c) at least one surfactant. Also described are methods for delivering a solvent at reduced concentration comprising the steps of: a) obtaining a terpene-based solvent; and b) mixing the terpene-based solvent with a carrier fluid (the carrier fluid comprising a microemulsion of i) a blend of dibasic esters selected from the group consisting of dialkyl methylglutarate, dialkyl adipate, dialkyl ethylsuccinate, dialkyl succinate, dialkyl glutarate and any combination thereof, ii) at least one surfactant selected from the group consisting of a terpene alkoxylate, an alcohol alkoxylate and any combination thereof; and iii) water) in order to obtain a mixture to clean heavy oils. | 2012-06-14 |
20120149627 | DETERGENT COMPOSITIONS AND METHODS OF MAKING - The present invention relates to a detergent composition for dish washing and clothes washing machines which includes an anionic surfactant, a non-ionic surfactant, and a foam control agent which includes polydimethylsiloxane, sodium acetate, and mixtures thereof. The detergent composition is in a dry form and is capable to reduce or preclude the formation of suds when combined with water. | 2012-06-14 |
20120149628 | SOLIDIFICATION MATRIX USING A POLYCARBOXYLIC ACID POLYMER - A solidification matrix includes a polycarboxylic acid polymer, sodium carbonate, and water. Exemplary polycarboxylic acid polymers include a polyacrylic acid polymer having a molecular weight of between about 1,000 and about 100,000, a modified polyacrylic acid polymer having a molecular weight of between about 1,000 and about 100,000, and a polymaleic acid polymer having a molecular weight of between about 500 and about 5,000. The polycarboxylic acid polymer, sodium carbonate, and water interact to form a hydrate solid. The solidification matrix may be used, for example, in a solid detergent composition. | 2012-06-14 |
20120149629 | PEARLESCENT CONCENTRATE AND PROCESS FOR PRODUCTION - The invention relates to pumpable aqueous pearlescent concentrates having a high active content of alkyl sulfates, alkyl ether sulfates, alkyl sulfonates, mono and diesters of sulfosuccinic acid (sulfosuccinates), alkyl glycinates, alkyl sarcosinates, and/or alkyl taurates, and fatty acid glycol esters and/or carbolic acid amides as pearlescent agents, and to a method for the production thereof. The pearlescent concentrates according to the invention are suitable as additives for improving the optical appearance of tenside components, for example of liquid washing and cleaning agents or liquid body wash and body care agents and hair care agents. The pearlescent concentrates according to the invention comprise 35 to 85% by weight of a dispersant selected from alkyl ether sulfates, alkyl sulfates, alkyl sulfonates, mono and diesters of sulfosuccinic acid, alkyl glycinates, alkyl sarcosinates and/or alkyl taurates, and mixtures thereof, 15 to 40% by weight of a pearlescent agent component selected from fatty acid glycol esters, fatty acid alkanol amides and mixtures thereof, optionally advantageous additives and water in the quantity short of 100% by weight, but not in a concentration greater than 30% by weight. | 2012-06-14 |
20120149630 | END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF - Poly(beta-amino esters) are end-modified to form materials useful in the medical as well as non-medical field. An amine-terminated poly(beta-amino ester) is reacted with an electrophile, or an acrylate-terminated poly(beta-amino ester) is reacted with a nucleophile. The inventive end-modified polymers may be used in any field where polymers have been found useful including the drug delivery arts. The end-modified polymers are particularly useful in delivery nucleic acids such as DNA or RNA. The invention also provides compositions including the inventive end-modified polymers, methods of preparing the inventive polymers, and method of using the inventive polymers. | 2012-06-14 |
20120149631 | ANTIMICROBIAL AND ANTIBIOFILM ACTIVITY OF CATHELICIDINS - The present disclosure relates to peptides, and fragments thereof, conferring antimicrobial and/or antibiofilm growth, as well as products and methodology for using same. | 2012-06-14 |
20120149632 | GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY - The invention relates to derivatives of glycopeptide and lipoglycopeptide antibiotics possessing an altered ionization state with respect to the parent glycopeptide or lipoglycopeptide antibiotic, and having the ability to be regenerated as the parent glycopeptide or lipoglycopeptide antibiotic under physiological conditions. These compounds are useful as antibiotics for the prevention and/or the treatment of bacterial infections. | 2012-06-14 |
20120149633 | MODULATION OF CD4+ T CELL RESPONSES BY A TICK SALIVA PROTEIN, SALP15 AND POLYPEPTIDES DERIVED THEREFROM - Salp15, biologically functional equivalents and fragments thereof, and nucleic acid molecules encoding the same are disclosed. Recombinant host cells, recombinant nucleic acids and recombinant proteins are also disclosed. Salp15 gene products and Salp15 polypeptide fragments have biological activity in modulating CD4+ T cell activation through specific binding to CD4. Thus, therapeutic methods involving modulating T cell activation using Salp15 and biologically active polypeptide fragments thereof are also disclosed. The specific binding of Salp15 and fragment peptides thereof to CD4 can inhibit HIV infection of T cells, and thus methods of using Salp15 for inhibiting HIV infection are also disclosed. Screening methods for selecting substances having an ability to modulate activation of T cells are also disclosed. | 2012-06-14 |
20120149634 | COMPOUNDS AND METHODS FOR TREATING BONE DISORDERS AND CONTROLLING WEIGHT - The present invention provides peptides and methods of their use in treating bone disorders and bone-related conditions and in treating obesity. | 2012-06-14 |
20120149635 | TREATMENT FOR OBESITY - The present invention provides peptides and pharmaceutical compositions thereof for appetite suppression and weight control. Preferred peptides are calcitonin analogs, preferably with specific amino acid changes to make the peptide more amylin-like. | 2012-06-14 |
20120149636 | Modified Leptin Polypeptides and Their Uses - Modified human leptin polypeptides and uses thereof are provided. | 2012-06-14 |
20120149637 | AMINOTETRAHYDROPYRANS AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES - The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. | 2012-06-14 |
20120149638 | METHODS FOR PREVENTING OR TREATING INSULIN RESISTANCE - The invention provides methods of preventing or treating insulin resistance in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (p | 2012-06-14 |
20120149639 | USE OF A DPP-IV INHIBITOR TO REDUCE HYPOGLYCEMIC EVENTS - The invention relates to a method to reduce the hypoglycemic events, especially severe hypoglycemic events resulting from insulin treatment, wherein the patient is treated with a Dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor) or a pharmaceutically acceptable salt thereof. | 2012-06-14 |
20120149640 | PEPTIDES MODULATING THE ACTIVITY OF IGF-1 AND THE APPLICATIONS OF SAID PEPTIDES - The invention relates to peptides for modulate IGF-1 activity, a pharmaceutical composition comprising them as well as their applications as medicinal products and cell proliferation modulating agents in vitro. | 2012-06-14 |
20120149641 | Methods and Compositions for Regenerating Articular Cartilage - Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent. | 2012-06-14 |
20120149642 | FIBROSIS INHIBITOR FOR IMPLANTED ORGAN - A pharmaceutical preparation comprising a hepatocyte growth factor or a DNA molecule encoding the same and the like according to the present invention can suppress the fibrosis of a transplanted organ after organ transplantation. The present invention is useful in the fields of organ transplantation and regeneration therapy. | 2012-06-14 |
20120149643 | Safe Desmopressin Administration - Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients. The dispensers of the invention may be used in the treatment of nocturia, primary nocturnal enuresis, incontinence, urinary frequency, diabetes insipidus, or any disease or syndrome where desmopressin therapy is useful or where safe temporary suppression of urine production may lead to beneficial health effects or increased convenience in voiding control. | 2012-06-14 |
20120149644 | COMPOSITIONS AND METHODS FOR TREATING GROWTH HORMONE DEFICIENCY - The present invention relates to methods of predicting the level of response to treatment with growth hormone in an individual having Growth Hormone Deficiency (GHD) or Turner Syndrome (TS). | 2012-06-14 |
20120149645 | COMPOSITIONS AND MODULATION OF MYOCYTE ENHANCER FACTOR 2 (MEF2) - The disclosure relates to mitochondrial myocyte enhancer factor 2 (MEF2), Parkinson's disease, and other related diseases. In certain embodiments, the disclosure relates to analyzing the levels of mitochondrial MEF2 isoforms and/or its mitochondrial target gene ND6 in peripheral blood cells such as white blood cells as an indicator for neuronal mitochondrial MEF2 or ND6 and correlated the level to disease diagnosis, treatment, and prognosis. | 2012-06-14 |
20120149646 | LONG TERM POTENTIATION WITH CYCLIC-GLUR6 ANALOGS - This invention discloses CN2097-like compositions that facilitate the induction of long-term potentiation (LTP). In one embodiment the method comprises inducing long-term potentiation in a subject by the method of administering a therapeutically effective dose of a CN2907-like compound. | 2012-06-14 |
20120149647 | Methods for Assessing the Efficacy of Gemcitabine or Ara-C Treatment of Cancer Using Human Antigen R Levels - Disclosed are compositions and methods relating to the treatment of a disease with a nucleoside analog, such as gemcitabine or Ara-C, and a polynucleotide construct encoding for an mRNA binding protein, such as Human antigen R. | 2012-06-14 |
20120149648 | THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active peptidomimetic macrocycles for the treatment of cell proliferative disorders such as cancer and immunoproliferative disease. | 2012-06-14 |
20120149649 | SHORT-CHAIN CATIONIC POLYAMINO ACID AND USE THEREOF - The present invention provides a cationic polyamino acid suitable for a carrier that can form a stable complex with a nucleic acid under a physiological condition and release the nucleic acid in cells suitably. The cationic polyamino acid can associate with a nucleic acid and includes a cationic amino acid residue having a cationic group in a side chain and a hydrophobic amino acid residue having a hydrophobic group in a side chain. The cationic polyamino acid includes 1 to 20 units of the cationic amino acid residue and is represented by the following formula (1). | 2012-06-14 |