24th week of 2011 patent applcation highlights part 43 |
Patent application number | Title | Published |
20110142716 | Microchip and Process for Producing Microchip - A microchip | 2011-06-16 |
20110142717 | EMISSIVE SENSORS AND DEVICES INCORPORATING THESE SENSORS - The present invention generally relates to luminescent and/or optically absorbing compositions and/or precursors to those compositions, including solid films incorporating these compositions/precursors, exhibiting increased luminescent lifetimes, quantum yields, enhanced stabilities and/or amplified emissions. The present invention also relates to sensors and methods for sensing analytes through luminescent and/or optically absorbing properties of these compositions and/or precursors. Examples of analytes detectable by the invention include electrophiles, alkylating agents, thionyl halides, and phosphate ester groups including phosphoryl halides, cyanides and thioates such as those found in certain chemical warfare agents. The present invention additionally relates to devices and methods for amplifying emissions, such as those produced using the above-described compositions and/or precursors, by incorporating the composition and/or precursor within a polymer having an energy migration pathway. In some cases, the compositions and/or precursors thereof include a compound capable of undergoing a cyclization reaction. | 2011-06-16 |
20110142718 | GLUCOSE SENSOR CHIP - According to one embodiment, a glucose sensor chip includes an optical waveguide layer on a main surface of a substrate, the optical waveguide layer including a pair of gratings which are separated each other, a sensing film on a surface of a portion of the optical waveguide layer between the pair of the gratings, the sensing film being constituted with a membrane polymer, a cross-linking polymer and a low-molecular compound, the sensing film including a first enzyme which oxidizes or reduces a color forming dye and a glucose, and a second enzyme which reacts with a product of the first enzyme and generates a material which produces the color forming dye. | 2011-06-16 |
20110142719 | CARBON MONOXIDE (CO) MICROSIR SENSOR SYSTEM - The present invention provides very small low cost apparatus and method for determining the concentration and/or hazard from a target gas by means of optically monitoring one or more sensors that responds to carbon monoxide. The apparatus comprises a photon source optically coupled to the sensor and the photon intensity passing through the sensor is quantified by one or more photodiode(s) in a system, so that the photon flux is a function of at least one sensor's response to the target gas, e.g., transmits light through the sensor to the photodiode. The photocurrent from the photodiode is converted to a sensor reading value proportional to the optical characteristics of the sensors and is loaded into a microprocessor or other logic circuit. In the microprocessor, the sensor readings may be differentiated to determine the rate of change of the sensor readings and the total photons absorbed value may be used to calculate the CO concentration. | 2011-06-16 |
20110142720 | METHOD FOR IMPROVING A POLYMERIZATION REACTION BY TAKING OUT AND ANALYSING A SAMPLE - The invention relates to a device for taking out and analysing a sample from a polymerisation reactor comprising one or more sample conduits ( | 2011-06-16 |
20110142721 | FUEL GASIFICATION EQUIPMENT - Provided is a fuel gasification equipment capable of effectively utilizing a CO | 2011-06-16 |
20110142722 | METHOD AND APPARATUS FOR PRODUCING SYNTHESIS GAS - A method and apparatus for reacting a hydrocarbon containing feed stream by steam methane reforming reactions to form a synthesis gas. The hydrocarbon containing feed is reacted within a reactor having stages in which the final stage from which a synthesis gas is discharged incorporates expensive high temperature materials such as oxide dispersed strengthened metals while upstream stages operate at a lower temperature allowing the use of more conventional high temperature alloys. Each of the reactor stages incorporate reactor elements having one or more separation zones to separate oxygen from an oxygen containing feed to support combustion of a fuel within adjacent combustion zones, thereby to generate heat to support the endothermic steam methane reforming reactions. | 2011-06-16 |
20110142723 | Exhaust Gas Purifying Device - An exhaust gas purifying device includes: a case body including a plurality of cases, and heat insulating rings and heat insulators that cover the case body over a substantially-entire area from an upstream side to a downstream side in an exhaust gas flowing direction. The heat insulators are placed inward from joint portions between the cases, and the heat insulating rings are placed in such a manner as to bridge over the joint portions between the cases. With the above arrangement, the surface temperature of the case body can be reliably prevented from becoming high. | 2011-06-16 |
20110142724 | SYSTEM FOR REFINING UMG Si USING STEAM PLASMA TORCH - Disclosed is a system for refining UMG Si including a vacuum chamber, a cold crucible disposed within the vacuum chamber, a device disposed within the vacuum chamber to supply Si to the cold crucible, a steam plasma torch disposed above the cold crucible to apply steam plasma formed by introducing a reactive gas into plasma flame by an inert gas to the Si supplied to the cold crucible, and an impurity collector disposed above the cold crucible within the vacuum chamber to collect impurity gas generated in the cold crucible and discharge the collected impurity gas to the outside of the vacuum chamber. | 2011-06-16 |
20110142725 | AIR PURIFICATION APPARATUS AND METHOD OF FORMING THE SAME - A photocatalytic air purification apparatus and method of fabricating the same. The apparatus may be configured to include a light source surrounded by one or more porous plate substrates. An inner and outer surface of each plate substrate may be coated with a photocatalyst material. The light source may be placed in a direction parallel to the direction of an air flow and in optical proximity to the plate substrates in order to activate the photocatalyst coating. The photocatalyst coating associated with the plate substrates may be activated by absorbing light with a wavelength shorter than a cut-off activation wavelength from the light source in order to capture and decompose organic components and airborne pollutants in the air by the activated photocatalyst. | 2011-06-16 |
20110142726 | NANOCARBON PRODUCING APPARATUS - According to one embodiment, a nanocarbon producing apparatus includes a heating vessel which provides a reducing atmosphere therein, a heating source disposed on an outer circumference of the heating vessel, a hydrocarbon injection nozzle disposed on an upstream side of the heating vessel for spraying hydrocarbon into the heating vessel, and a nanocarbon product discharge nozzle disposed on a downstream side of the heating vessel, wherein a metallic substrate is disposed on an inside surface of the heating vessel and the hydrocarbon is continuously sprayed from the hydrocarbon injection nozzle, effecting a reaction to grow nanocarbon on the metallic substrate, and the grown nanocarbon product is peeled off from the metallic substrate and discharged through the discharge nozzle. | 2011-06-16 |
20110142727 | METHOD OF GROWING CARBON NANOTUBE AND CARBON NANOTUBE GROWING SYSTEM - When growing carbon nanotubes, a substrate is delivered into a thermal CVD chamber whose internal temperature is a room temperature, and a mixed gas of an inert gas and a raw gas is introduced in the inside thereof. After a pressure inside of the chamber is stabilized at 1 kPa, the temperature in the chamber is raised to 510° C. in 1 minute. As a result, the carbon nanotubes start to grow linearly from the respective catalytic particles without any fusion of each of the catalytic particles. Subsequently, the temperature and an atmosphere are maintained for about 30 minutes. Once the carbon nanotubes start to grow, surfaces of the catalytic particles are covered by carbon, so that any fusion of each of the catalytic particles can be avoided even during the maintenance for about 30 minutes. | 2011-06-16 |
20110142728 | SELECTIVE CATALYTIC OXIDATION OF AMMONIA TO WATER AND NITROGEN - A catalyst includes a platinum coating deposited on a silica support. The support has an average surface area between about 100 m | 2011-06-16 |
20110142729 | APPARATUS FOR PRODUCING HYDROCARBON FUEL - Slurry hydrocracking a heavy hydrocarbon feed produces a HVGO stream and a pitch stream. At least a portion of the pitch stream is subjected to SDA to prepare a DAO stream low in metals. The DAO is blended with at least a portion of the HVGO stream to provide turbine or marine fuel with acceptable properties for combustion in gas turbines or for marine fuel grades. | 2011-06-16 |
20110142730 | Crystalline Silicon Formation Apparatus - In a crystalline silicon formation apparatus, a quick cooling method is applied to the bottom of a crucible to control a growth orientation of a polycrystalline silicon grain, such that the crystal grain forms twin boundary, and the twin boundary is a symmetric grain boundary, and the crystal grain is solidified and grown upward in unidirection to form a complete polycrystalline silicon, such that defects or impurities will not form in the polycrystalline silicon easily. | 2011-06-16 |
20110142731 | DEVICE FOR STERILIZING CLOSURES - The invention relates to a device for sterilizing caps or the like closures for closing bottles or the like containers. Said device comprises a conveyor system conveying the caps in a direction of conveyance through a treatment section having a plurality of successive treatment stations in the direction of conveyance. | 2011-06-16 |
20110142732 | Resonance Chamber, Especially For An Apparatus For Pasteurization Of Liquid Products - The resonance chamber ( | 2011-06-16 |
20110142733 | Diffusive Sampling Device - A kit of parts is for assembling a diffusive dosimeter for the detection of pollutants, said kit of parts includes a housing ( | 2011-06-16 |
20110142734 | DEVICE AND METHOD FOR PRESSURE-DRIVEN PLUG TRANSPORT - The present invention provides microfabricated substrates and methods of conducting reactions within these substrates. The reactions occur in plugs transported in the flow of a carrier-fluid. | 2011-06-16 |
20110142735 | METHOD FOR SEPARATING RADIOACTIVE COPPER USING CHELATING-ION EXCHANGE RESIN - Disclosed is a method for rapidly separating radioactive copper from nickel that contains radioactive copper and radioactive cobalt, which comprises dissolving nickel that contains radioactive copper and radioactive cobalt in an acid solution and leading it to pass through a chelating-ion exchange resin-filled column to thereby make nickel, radioactive copper and radioactive cobalt held by the chelating-ion exchange resin, and then leading an acid solution to pass through the chelating-ion exchange resin-filled column to elute nickel and radioactive cobalt, and thereafter leading an acid solution having a higher concentration than that of the previous acid solution to pass through the chelating-ion exchange resin-filled column after nickel and radioactive elution therefrom to thereby elute radioactive copper. | 2011-06-16 |
20110142736 | PROCESS OF RECOVERY OF BASE METALS FROM OXIDE ORES - A method for recovering base metal values from oxide ore is provided, where the ore includes a first group metal selected from iron, magnesium and aluminum and a second group metal selected from nickel, cobalt and copper. The method includes reducing ore particle size to suit the latter unit operations, favoring contact of the metal elements, contacting the ore with ferric or ferrous chloride, hydrated or anhydrous, to produce a mix of ore and iron(II or III) chloride, subjecting the mixture of the ore and ferric or ferrous chloride to enough energy to decompose the chlorides into hydrochloric acid and a iron oxide, contacting the readily-formed hydrochloric acid with the base metal oxides from the second group, forming their respective chlorides, selectively dissolve the produced base metal chlorides, leaving the metals as oxides and in the solid state, and recovering the dissolved base metal values from aqueous solution. | 2011-06-16 |
20110142737 | SELECTIVE CATALYTIC REDUCTION OF NITROGEN OXIDES IN THE EXHAUST GAS OF DIESEL ENGINES - A catalyst and a process for selective catalytic reduction of nitrogen oxides in diesel engine exhaust gases with ammonia or a compound decomposable to ammonia are described. The exhaust gas to be cleaned is passed together with ammonia or a compound decomposable to ammonia over a catalyst which comprises a zeolite or a zeolite-like compound containing 1-10% by weight of copper, based on the total weight of the zeolite or of the zeolite-like compound, and a homogeneous cerium-zirconium mixed oxide and/or a cerium oxide. The zeolite used or the zeolite-like compound used is selected from the group consisting of chabazite, SAPO-34, ALPO-34 and zeolite-β. | 2011-06-16 |
20110142738 | METHOD FOR TREATING SPENT REGENERATION GAS - The invention covers a method for treating spent regeneration gas from one or more molecular sieve treaters, first in an amine solvent unit and then in a caustic unit. The amine solvent unit removes hydrogen sulfide and carbonyl sulfide and the caustic unit removes mercaptans. Optionally, there are additional treatments before the treated gas has met specifications for burning as a fuel or used for other purposes. | 2011-06-16 |
20110142739 | MULTI-COMPARTMENT OVERFIRE AIR AND N-AGENT INJECTION METHOD AND SYSTEM FOR NITROGEN OXIDE REDUCTION IN FLUE GAS - A method of decreasing a concentration of nitrogen oxides in a combustion gas flowing through a vessel including: generating a flue gas in a combustion zone of the vessel, the flue gas containing nitrogen oxides and carbon monoxide; providing overfire air into a burnout zone of the vessel from a first injector of overfire air to oxidize at least some of the carbon monoxide in the flue gas; injecting a selective reducing agent concurrent with overfire air at a level in the burnout zone downstream of the first injector of overfire air and downstream of the oxidization of the carbon monoxide, and reacting the selective reducing agent with the flue gas to reduce the nitrogen oxides. | 2011-06-16 |
20110142740 | METHOD AND SYSTEM FOR TREATMENT OF MALODOROUS GASES EMANATING FROM A PULP MILL - The method and system relate to reducing the content of hazardous chemicals when handling malodorous gases emanating from a pulp mill and before burning said malodorous gases in final incineration equipment in oxygen excess environment in order to oxidize the sulphur compounds. The flow of malodorous gases is transported to final incineration (C | 2011-06-16 |
20110142741 | CRYSTAL GROWTH IN SOLUTION UNDER STATIC CONDITIONS - A method for growing crystals in solution is suitable for the rapid, controlled and effective preparation of crystals of large dimensions from a solution supersaturated with a compound. The crystal growth is carried out under static conditions. To do this: the growth is performed in a crystallisation chamber kept at a constant temperature T | 2011-06-16 |
20110142742 | METHOD FOR PURIFICATION OF SILICON TETRACHLORIDE - An object of the present invention is to provide a method for purification of silicon tetrachloride which solves the problems of separating and removing organic chlorosilanes by distillation or adsorption. | 2011-06-16 |
20110142743 | ISOLATION OF SINGLE-WALLED CARBON NANOTUBES FROM DOUBLE AND MULTI-WALLED CARBON NANOTUBES - A method and system are disclosed for separating single-walled carbon nanotubes from double and multi-walled carbon nanotubes by using the difference in the buoyant density of Single-Walled versus Multi-Walled carbon nanotubes. In one embodiment, the method comprises providing a vessel with first and second solutions. The first solution comprises a quantity of carbon nanotubes, including single-walled carbon nanotubes and double and multi-walled carbon nanotubes. The single walled nanotubes have a first density, the double and multi-walled nanotubes having a second density. The second solution in the vessel has a third density between said first and second densities. The vessel is centrifuged to form first and second layers in the vessel, with the second solution between said first and second layers. The single-walled carbon nanotubes are predominantly in the first layer, and the second and multi-walled carbon nanotubes are predominantly in the second layer. | 2011-06-16 |
20110142744 | METHOD FOR MAKING CARBON NANOTUBE STRUCTURE - The present disclosure relates to a method for making a carbon nanotube carbon nanotube structure. The method includes steps of providing a tubular carbon nanotube array; and drawing out a carbon nanotube structure from the tubular carbon nanotube array by using a drawing tool. The carbon nanotube structure is a carbon nanotube film or a carbon nanotube wire. | 2011-06-16 |
20110142745 | METHOD AND APPARATUS FOR FORMING CARBON NANOTUBE ARRAY - The present disclosure relates to a method for forming a carbon nanotube array. In the method a tubular substrate is provided. The tubular substrate includes an outer sidewall with a catalyst layer located on the outer sidewall. The heating member, and the tubular substrate with the catalyst layer is received in a reacting chamber. The tubular substrate is heated by the heating member. A carbon source gas is supplied into the reacting chamber to grow the carbon nanotube array on the tubular substrate. | 2011-06-16 |
20110142746 | SYSTEM AND PROCESS FOR CADMIUM TELLURIDE (CdTe) RECLAMATION IN A VAPOR DEPOSITION CONVEYOR ASSEMBLY - A conveyor assembly for use in a vapor deposition apparatus wherein a sublimed source material is deposited as a thin film on a photovoltaic (PV) module substrate. The assembly includes a conveyor movable in an endless loop path that includes an upper leg that moves in a conveyance direction to carry a substrate through a deposition area of the vapor deposition apparatus. A heat source is disposed relative to the endless loop path so as to heat the conveyor at a location generally after the point where substrates leave the conveyor. The heat source heats the conveyor to a temperature effective for sublimating source material from the conveyor. A cold trap is disposed relative to the endless loop path downstream of the heat source in a direction of movement of the conveyor and is maintained at a temperature effective for causing sublimated source material generated from heating the conveyor to plate out onto a collection member configured with the cold trap. An associated process for reclamation of source material from conveyor components is also provided. | 2011-06-16 |
20110142747 | THREE PHASE SULFUR SEPARATION SYSTEM WITH INTERFACE CONTROL - A liquid separator system having a gas phase zone, an aqueous phase zone and a denser liquid zone is used to separate mixtures of fluids. The separator can be used for separating molten sulfur from liquid redox solution or reslurry water. The system includes a vessel with a top part and a bottom part. The vessel has a larger diameter at the top part than at the bottom part. The system also includes an inlet for introducing a redox solution or reslurry water and molten sulfur, which is denser than redox solution or reslurry water, into the vessel. An outlet near the bottom part of the vessel allows a flow of the molten sulfur from the vessel. An interface control structure senses an interface level between the redox solution or reslurry water and the molten sulfur, and the interface control structure controls the flow of molten sulfur from the outlet. The interface control structure is adjusted to optimally alter the vertical height of the interface level within the vessel so that the residence time of the molten sulfur in the vessel does not decrease as the sulfur production throughput decreases, and so that the interface area of the molten sulfur and the redox solution is reduced as the sulfur throughput decreases. A pressure controller monitors the pressure in the vessel and adds or removes gas from a gas phase zone in the vessel to maintain a predetermined pressure regardless of the vertical height of the interface. | 2011-06-16 |
20110142748 | PROCESS FOR THE PRODUCTION OF OXYGEN AT HIGH TEMPERATURE WITH MATERIALS OF THE MANGANESE OXIDES TYPE HAVING A LAMELLAR STRUCTURE - The present invention relates to a process for separating oxygen at high temperature by means of a material comprising at least one compound according to the formula A | 2011-06-16 |
20110142749 | ALUMINUM HYDROXIDE GEL PARTICLE AND PRODUCTION METHOD THEREOF - An aluminum hydroxide gel particle having high purity and extremely high acid reactivity and a production method thereof. | 2011-06-16 |
20110142750 | HYBRID HYDROGEN STORAGE SYSTEM AND METHOD USING THE SAME - According to one aspect of the present invention, a hybrid hydrogen storage system is provided. In one embodiment, the hybrid hydrogen storage system includes: a first hydrogen storage material present at a first volume percent (%) having a first gravimetric capacity and a first volumetric capacity; and a second hydrogen storage material forming an unreacted mixture with the first hydrogen storage material and present at a second volume % being 100 volume % minus the first volume %, the second storage material having a second gravimetric capacity and a second volumetric capacity, the first gravimetric capacity at the first volume % being higher or lower than the second gravimetric capacity at the second volume %, and the first volumetric capacity at the first volume % being the other of higher or lower than the second volumetric capacity at the second volume %. | 2011-06-16 |
20110142751 | HYDROGEN GENERATOR - A device includes a chemical hydride fuel pellet having a plurality of holes extending from a first end to a second end. A plurality of tubes formed of water vapor permeable and hydrogen impermeable material extend from the first end to the second end through the tubes. A container has an inlet for water vapor containing gas coupled to the first end of the tubes and an outlet coupled to the second end of the tubes. A hydrogen outlet is coupled to the fuel pellet. | 2011-06-16 |
20110142752 | Hydrogen Storage Materials - In one embodiment, a hydrogen storage system includes a core of hydrogen sorbent material and a shell of crystalline metal hydride material enclosing at least a portion of the core of hydrogen sorbent material. In another embodiment, the hydrogen storage system further includes an intermediate layer of amorphous metal hydride material, at least a portion of which being positioned between the core of hydrogen sorbent material and the shell of crystalline metal hydride material. | 2011-06-16 |
20110142753 | DROPLET IMPINGEMENT CHEMICAL REACTORS AND METHODS OF PROCESSING FUEL - Fuel processors, methods of using fuel processors, and the like, are disclosed. | 2011-06-16 |
20110142754 | ONE-OFF AND ADJUSTMENT METHOD OF HYDROGEN RELEASING FROM CHEMICAL HYDRIDE - An one-off and adjustment method of hydrogen releasing from chemical hydride. The “one/off” of hydrogen release is controlled by the “contact/non-contact” procedures between the reactants. First, at least a hydride powder, a catalyst powder and a water-containing reactant are provided, and at least any two of three are mixed to form a mixture. Hydrogen gas is generated by adjusting a contact area between the mixture and the remaining one. The hydrogen-releasing reaction is terminated when a non-contacting state between the mixture and the remaining one occurs. Alternatively, an inhibitor or an inhibiting method could be used for suppressing or terminating the hydrogen-releasing reaction. The hydrogen-releasing rate could be controlled and adjusted by the extent of suppression. | 2011-06-16 |
20110142755 | PROCESS FOR THE PREPARATION OF ZEOLITES HAVING B-CHA STRUCTURE - The present invention relates to a process for the preparation of zeolites having B-CHA framework structure and a composition comprising the molar ratio (n SiO | 2011-06-16 |
20110142756 | Method And Composition For The Treatment Of Cancer By The Enzymatic Conversion Of Soluble Radioactive Toxic Precipitates In The Cancer - The invention features compositions and methods for treating or alleviating a symptom of cancer. The compositions and methods of the invention direct supra-lethal doses of radiation, called Hot-Spots, to virtually all cancer cell types. | 2011-06-16 |
20110142757 | NOVEL COMPOUNDS AND THEIR USES IN DIAGNOSIS - A compound of formula (I) wherein, X and Y independently bind TSPO, wherein X and Y are the same or different; and L is a linker that links X to Y; or a salt or solvate thereof. For preference, X and Y may be (II) or (III). The compounds may be radiolabeled with a radioisotope. Also methods for diagnosing or treating TSPO related disorders such as neurodegenerative disorder, inflammation or anxiety, eg. Alzheimer's disease, Parkinson's disease, Huntington's disease, multiple sclerosis, multiple system atrophy, epilepsy, encephalopathy, stroke, brain tumour, anxiety, stress, emotional disturbances or cognitive impairment, glioblastoma, ischemic stroke, herpes encephalitis, HIV, amyotrophic lateral sclerosis, corticobasal degeneration, cancer, depression, an auto-immune disease and an infectious disease. | 2011-06-16 |
20110142758 | INDOLYL-PYRIDAZINYL-DIAZABICYCLONONANE DERIVATIVES IN LABELLED AND UNLABELLED FORM AND THEIR USE IN DIAGNOSTIC METHODS - The present invention relates to indolyl-pyhdazinyl-diazabicyclononane derivatives in their labelled and unlabelled form. Furthermore, the present invention relates to the use of said derivatives in their labelled or unlabelled form in diagnostic methods, in particular for in vivo receptor imaging (neuroimaging). | 2011-06-16 |
20110142759 | AGENTS AND METHODS FOR THE IMAGING OF MYELIN BASIC PROTEIN - The present invention relates to agents capable of binding to myelin basic protein in a subject. Also provided are methods for the detection of myelin-associated neuropathy comprising identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, administering to a subject an agent that binds specifically to myelin basic protein, and determining myelination in the subject by detecting the agent present in the subject. A kit containing the agent or its derivatives for use in detecting myelin basic protein is also provided. | 2011-06-16 |
20110142760 | PSMA-BINDING AGENTS AND USES THEREOF - Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis. | 2011-06-16 |
20110142761 | IL-1 BINDING PROTEINS - The present invention describes IL-1β binding proteins, including chimeric, CDR-grafted, and humanized antibodies that bind IL-1β. Binding proteins of the invention have high affinity for IL-1β and neutralize IL-1β activity. A binding protein of the invention can be a full-length antibody or an IL-1β-binding portion thereof. Methods of making and methods of using the binding proteins of the invention are also described. The IL-1β binding proteins of the invention are useful for detecting IL-1β and for inhibiting IL-1β activity, including in a human subject suffering from a disease or disorder in which IL-1β activity is detrimental. | 2011-06-16 |
20110142762 | Conjugates for medical imaging comprising carrier, targeting moiety and a contrast agent - This invention relates to the delivery of agents to the body. One particular class of such agents are contrast agents useful in medical imaging techniques. The agents may be metals useful as contrast agents in magnetic resonance imaging (MRI), or in nuclear imaging, including positron emission tomography (PET), or as therapeutic agents in radiotherapy. The agents may alternatively be contrast agents useful in X-ray imaging. The invention also relates to methods by which agents for delivery to the body can be coupled to carriers and to targeting moieties effective to direct the agent to a specific locus within the body. | 2011-06-16 |
20110142763 | Megalin-Based Delivery of Therapeutic Compounds to the Brain and Other Tissues - The present invention is directed to a methods and compositions for receptor mediated drug delivery, particularly across the blood-brain barrier. | 2011-06-16 |
20110142764 | CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESIS AGENT AND USES THEREOF IN THE TREATMENT AND MONITORING OF BONE RELATED DISEASES - Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing same, are disclosed. | 2011-06-16 |
20110142765 | NOVEL PHLOROGLUCINOL DERIVATIVES HAVING SELECTIN LIGAND ACTIVITY - Pharmaceutical compositions comprising at least one compound of the formula (I) and a pharmaceutically acceptable carrier which is useful in a medicine wherein the symbols and substituents have the following meaning —X— is e.g. and Y being e.g. or the pharmaceutically acceptable salts, esters or amides and prodrugs can be applied to modulate the in-vitro and in-vivo binding processes mediated by E-, P- or selectin binding. | 2011-06-16 |
20110142766 | Effervescent Multi-Vitamin Formulation and Methods of Use Thereof - The present invention provides an effervescent dietary supplement formulation that may be beneficial to the management of symptoms related to ocular diseases. Also provided are methods of treating an ocular disease, such as macular degeneration, by administering the dietary supplement to a subject in need thereof. | 2011-06-16 |
20110142767 | RNAi-MEDIATED INHIBITION OF TUMOR NECROSIS FACTOR ALPHA-RELATED CONDITIONS - RNA interference is provided for inhibition of tumor necrosis factor α (TNFα) by silencing TNFα cell surface receptor TNF receptor-1 (TNFR1) mRNA expression, or by silencing TNFα converting enzyme (TACE/ADAM17) mRNA expression. Silencing such TNFα targets, in particular, is useful for treating patients having a TNFα-related condition or at risk of developing a TNFα-related condition such as the ocular conditions dry eye, allergic conjunctivitis, or ocular inflammation, or such as dermatitis, rhinitis, or asthma, for example. | 2011-06-16 |
20110142768 | CALCIUM PEROXYPHOSPHATES AND USE THEREOF IN DENTAL COMPOSITIONS - Calcium peroxyphosphate compounds and dental compositions comprising these compounds that combine both whitening/stain removal of teeth with remineralization are disclosed. The calcium peroxyphosphate compounds are capable of releasing, in an aqueous environment, whitening and remineralization effective amounts of calcium ion, phosphate ion, and active oxygen. Preferred compounds are calcium peroxymonophosphate or calcium diperoxymonophosphate compounds. These compounds may be used in humans and other animals, including other mammals. | 2011-06-16 |
20110142769 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM - An active agent delivery composition is provided that allows topical delivery of active agents including vitamin A and its derivatives. A polyhalogenic vehicle such as methoxyonafluorobutane or ethoxyonafluorobutane serves as a coupler for an active agent and a silicone carrier so as to allow solubilization of active agents not normally miscible in silicones and providing a moisture maintaining composition. | 2011-06-16 |
20110142770 | SUNSCREEN COMPOSITIONS INCORPORATING METHYLCELLULOSE AS AN SPF AND/OR PPD BOOSTER AND METHODS - Described are sunscreen compositions, comprising organic pigment particulates and methylcellulose, and methods of boosting the SPF (sun protection factor) and/or PPD (Persistent Pigment Darkening) of a sunscreen composition having organic pigment particulates, comprising including methylcellulose in the sunscreen composition. | 2011-06-16 |
20110142771 | Photostabilization of Retinoids with Alkoxycrylene Compounds - The photostabilizing electronic excited state energy—particularly singlet state energy from retinoid compounds—has been found to be readily transferred to (accepted by) α-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinafter “alkoxycrylenes”) on one of the phenyl rings having the formula (I): | 2011-06-16 |
20110142772 | COMPOSITIONS - The present invention relates to topical compositions comprising at least 3 wt.-% of polysilicones-15, at least 4.5 wt.-% of butyl methoxydibenzoylmethane and at least 3 wt.-% of phenylbenzimidazol sulfonic acid in combination with at least 10 wt.-%, preferably at least 12 wt.-% of at least one further UVB and/or broadband-filter substance. | 2011-06-16 |
20110142773 | COMPOSITION AND PERIODICAL DELIVERY SYSTEM FOR CELLULAR REJUVENATION - A composition and delivery system is provided. The composition for skin treatment includes a plurality of autologous human adult adipose stem cells an activating cream, an effective amount of coenzyme Q10, an effective amount of GHK-Cu complex peptide, an effective amount of Ascorbate, an effective amount of Human Telomerase Reverse Transcriptase, an effective amount of Lipoic Acid, an effective amount of Rosa Mosqueta oil and delivery system for the composition including a housing unit, a plurality of chambers, an insulated partition defining the chambers, a plurality of internal singular vial apertures within the insulated partition connecting the chambers, an internal motor unit, a central processing unit and at least one storage container containing at least one vial. | 2011-06-16 |
20110142774 | OIL-IN-OIL TYPE COSMETIC COMPOSITION - The present invention provides an oil-in-oil type cosmetic composition that has excellent transfer resistance after application, a luster, favorable spreadability during application, and also excellent stability. The oil-in-oil type cosmetic composition comprises (a) 5 to 80% by mass of non-volatile hydrocarbon oil, (b) 1 to 70% by mass of non-volatile silicone oil, and (c) 0.1 to 10% by mass of dextrin fatty acid ester. Preferably, the non-volatile hydrocarbon oil (a) and the non-volatile silicone oil (b) are formulated at a ratio (mass ratio) of (a)/[(a)+(b)]=0.4 to 0.8. | 2011-06-16 |
20110142775 | COSMETIC AND DERMATOLOGICAL FORMULATIONS WITH NATURAL PIGMENTS AND METHODS OF USE - Pigments from plant products can be combined with a cosmetic carrier formulation to create a cosmetic and/or dermatological product for transferring color to the skin of the person. A plant product extract or reformulation, such as a concentrate, flake or powder of the plant, can be combined with a cosmetic carrier formulation to create a cosmetic and/or dermatological product for transferring color to the skin of the person. In some embodiments, fruits, vegetables, seeds and legumes can be used to extract natural pigment or reformulate a plant product into a concentrate, flake or powder. Resultant cosmetic products can include lipstick, lip gloss, lip stain, lip liner, blush, face tint, cheek stain, cheek gel, cheek butter, eye shadow, eyebrow powder, eyeliner, mascara, foundation, sheer foundation, bronzer, facial illuminator, facial highlighter, face powder, lotion and tinted moisturizer. | 2011-06-16 |
20110142776 | DIVINYL ETHER DERIVATIVES CAPABLE OF RELEASING ACTIVE ALDEHYDES AND KETONES AND METHODS OF USE FOR PERFUMING SURFACES - The present invention provides divinyl ether derivatives capable of releasing in a controlled manner at least one active aldehyde and/or ketone into the surrounding environment. The invention relates to the use of these divinyl ether derivatives as perfuming or flavoring ingredients, as well as to the perfuming compositions and consumer articles containing them. | 2011-06-16 |
20110142777 | Use of indole compounds as a cosmetic - The invention relates to a compound of formula I | 2011-06-16 |
20110142778 | Shampoo Composition Having Improved Care Properties - The invention relates to a cosmetic preparation that contains (a) at least one surfactant selected from anionic, zwitterionic or amphoteric surfactants, (b) a microemulsion and (c) at least one cationic polymer. | 2011-06-16 |
20110142779 | PERSONAL CARE COMPOSITIONS WITH TERTIARY AMINO MODIFIED CELLULOSE DERIVATIVES - Described are personal care compositions, comprising an aqueous dispersion comprising an ethylene acrylic acid copolymer and a least one cosmetically acceptable surfactant, emollient, or cosmetic active. | 2011-06-16 |
20110142780 | AGENT FOR KERATIN-CONTAINING FIBERS, COMPRISING AT LEAST ONE PARTICULAR AMPHIPHILIC CATIONIC POLYMER AND AT LEAST ONE POLYMER WITH SILICON-CONTAINING SIDECHAINS AND ANIONIC GROUPS - Agent for treating keratin-containing fibers, particularly, human hair, containing in a cosmetically-acceptable vehicle: (a) at least one amphiphilic, cationic polymer having at least one formula (I) structural unit, at least one formula (II) structural unit, at least one formula (III) structural, and at least one formula (IV) structural unit, where R | 2011-06-16 |
20110142781 | AGENT FOR FIBERS CONTAINING KERATIN, COMPRISING AT LEAST ONE SPECIFIC AMPHIPHILIC CATIONIC POLYMER AND AT LEAST ONE SPECIFIC, ADDITIONAL FILM-FORMING ANIONIC AND/OR STABILIZING ANIONIC POLYMER - Agent for treating fibers containing keratin, particularly human hair, having in a cosmetically acceptable carrier, (a) at least one amphiphilic, cationic polymer comprising at least one structural unit of formulae (I) to (IV), wherein R | 2011-06-16 |
20110142782 | Multi-functional, all-use, environmentally-friendly (Green) Soap - A bar of soap that will help the environment, solve an age old problem of what to do with the annoying pieces of leftover soap, save consumers money by using the complete bar of soap and provide additional functions from one bar of soap. | 2011-06-16 |
20110142783 | [(4E, 4Z)-5-METHOXY-3-METHYL-4-PENTENYL]-BENZENE AND ITS USE IN PERFUME COMPOSITIONS - The present invention is directed to a novel compound, [(4E, 4Z)-5-methoxy-3-methyl-4-pentenyl]-benzene, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of this novel compound. | 2011-06-16 |
20110142784 | Adhesive agent for application on a sanitary object - An agent for the sanitary sector, which agent can be applied directly on the sanitary object, adheres there and can be flushed away only after a relatively large number of flushing operations. The agent includes fillers from the group of surfactants and also an adhesion promoter. The adhesion promoter is selected from the group of polyalkylene derivatives which include polyalkylene chains with randomly distributed functional groups, or from the group of copolymers from the group of monoalkylesters of poly/methyl vinylethers/carboxylic anhydrides, olefin homopolymers and copolymers of two or more olefins being partially oxidized or further functionalized via graft molecules, and from the group of polyalkyleneimines, also in alkoxylated form, polyether amines (alkoxylated amines) and polyglycerol polyether alkylcarboxylic acids or polymers or derivatives containing these polymer groups. The viscosity of the agent is at least 30 Pas, measured using a Haake viscometer, plate/plate system, plate diameter 10 mm, at a shear gradient of 2.62 s | 2011-06-16 |
20110142785 | Adhesive agent for application on a sanitary object - An agent for the sanitary sector, which agent can be applied directly on a sanitary object, adheres there and can be flushed away only after a relatively large number of flushing operations. The agent includes fillers from the group of surfactants and also an adhesion promoter. The adhesion promoter is selected from hydrogenated polystyrene derivatives and olefin homopolymers and copolymers of two or more olefins, where the olefin homopolymers and copolymers may also be partially hydrogenated, and the viscosity of the agent is at least 30 Pas, measured using a Haake viscometer, plate/plate system, plate diameter 10 mm, at a shear gradient of 2.62 s | 2011-06-16 |
20110142786 | LENS CARE SOLUTIONS FUNCTIONALIZED ALKYLDIMONIUM HYDROXYPROPYL ALKYLGLUCOSIDES - A contact lens care solution that includes a functionalized hydroxypropyl alkylglucoside. The functionalized hydroxypropyl alkylglucoside is typically in the form a mixture of various alkylglycosides because: (1) the functional reagents can react with any one or more of the many hydroxyl groups on the glycoside; and (2) the glycosides are present as a mixture of glycosides with a degree of polymerization from 1 to about 4. The solution will also include a buffer system to maintain the pH of the composition from 7.2 to 8.5. In particular, the solution can be formulated to clean and disinfect contact lenses or the solution is formulated as a rewet eye drop for use with contact lenses. | 2011-06-16 |
20110142787 | POLYMERIZED CYCLIC NITROXIDE RADICAL COMPOUND AND USE THEREOF - A method of covalently bonding a cyclic nitroxide radical compound to a hydrophobic block of a specific hydrophylic-phobic block copolymer, and polymerized cyclic nitroxide radical compound copolymerized in this manner, as well as use of such a compound, for instance, in the medical field are provided. The compound demonstrates long term stability in vivo under reductive environment. | 2011-06-16 |
20110142788 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE ORGANIC STRUCTURING AGENT, AT LEAST ONE ABSORBENT MIXTURE AND AT LEAST ONE SURFACTANT FOR APPLICATION TO KERATIN MATERIALS - Provided herein is an anhydrous cosmetic composition comprising at least one organic structuring agent, at least one modified starch, at least one wood meal, at least one surfactant, and at least one anhydrous liquid phase. Also provided is a method for cleansing and/or conditioning keratin materials, comprising applying at least one of the anhydrous cosmetic compositions to the keratin materials. | 2011-06-16 |
20110142789 | Compositions and Methods for the Diagnosis and Treatment of Amyotrophic Lateral Sclerosis - Compositions and methods for diagnosis and treatment of ALS are provided. | 2011-06-16 |
20110142790 | Polyol Based - Bioceramic Composites - Polyol-bioceramic composites are prepared by the reaction of a polyol and polycarboxylic acid in the presence of a bioceramic. Implantable medical devices fabricated at least in part with the crosslinked polyol-bioceramic composite materials are useful in a wide variety of applications. | 2011-06-16 |
20110142791 | COMPOSITIONS AND METHODS FOR PREVENTION OF ESCAPE MUTATION IN THE TREATMENT OF HER2/NEU OVER-EXPRESSING TUMORS - This invention provides compositions and methods for treating and vaccinating against an Her2/neu antigen-expressing tumor and inducing an immune response against dominant and several sub-dominant epitopes of the antigen. | 2011-06-16 |
20110142792 | Compositions for Increasing Polypeptide Stability and Activity, and Related Methods - This disclosure provides peptides, polypeptides, fusion polypeptides, compositions, and methods for enhancing or increasing the stability of a polypeptide (e.g., Taq polymerase). Such peptides, polypeptides, fusion polypeptides, or compositions include polypeptides linked to a peptide tag that enhances the stability of the polypeptide. The peptides, polypeptides, fusion polypeptides, compositions may also enhance the activity, specificity, and/or fidelity of other polypeptides in a reaction mixture. The disclosure also provides methods of using such peptides, polypeptides, fusion polypeptides, compositions. | 2011-06-16 |
20110142793 | COMPOSITION FOR TREATING ARTICULAR CARTILAGE DEFECT, AND METHOD OF MANUFACTURE THEREOF - The present invention provides a composition for treating an articular cartilage defect and a manufacturing method thereof. The composition comprises a cartilage fragment and platelet-rich fibrin (PRF), and is transplanted to a surface of the defective cartilage of a mammal in order to treat the articular cartilage defect. Wherein the cartilage fragment is acquired from the cartilage of the same mammal, and the PRF is acquired from the blood of the same mammal. | 2011-06-16 |
20110142794 | Methods and Compositions to Determine the Chemosensitizing Dose of Suramin Used in Combination Therapy - A method for determining a therapeutically effective amount of suramin for administering to a patient, who is to receive a cytotoxic agent, which comprises the steps of determining the circulating suramin concentration in the patient; administering suramin, if required, to establish a low circulating concentration of suramin in the patient of below about 200 μM; and administering the chemotherapeutic agent to the patient when the low circulating concentration of suramin is present in the patient. Conveniently a nomogram can be constructed for use in clinical settings with the suramin. | 2011-06-16 |
20110142795 | METHODS OF TREATING COGNITIVE IMPAIRMENT - The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one or more inflammatory mediator(s), for example, fms-related tyrosine kinase 3 (Flt3) ligand, interleukin-6 (IL-6), macrophage migration inhibitory factor (MIF), interleukin-1 (IL-1), interleukin-3 (IL-3), erythropoietin (EPO), vascular endothelial growth factor A (VEGF-A), hypoxia-inducible transcription factor (HIF-1alpha), insulin like growth factor-1 (IGF-1), tumor necrosis factor (TNF), granulocyte colony-stimulating factor (G-CSF), granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF), Stem Cell Factor (SCF), Darbepoetin (ARANESP), and metalloproteinases, to an animal or person in need of treatment. | 2011-06-16 |
20110142796 | Fused Pyridine, Pyrimidine and Triazine Compounds as Cell Cycle Inhibitors - Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives. | 2011-06-16 |
20110142797 | Method For Prophylaxis or Treatment of Feline Infectious Peritonitis - Provided is a method for treatment and/or prophylaxis of FIP in cats. The method is performed by administering to a cat a composition comprising a therapeutic and/or prophylactic amount of a cysteine protease inhibitor. The cysteine protease inhibitor can be a selective cathepsin B inhibitor. Also provided is a method for inhibiting FIPV replication. The method comprises contacting a cell infected with FIPV with a cysteine protease inhibitor in an amount effective to inhibit replication of FIPV. It is expected the method will be effective for therapy or prophylaxis of FIP in any species of cat and will be effective against any strain of feline coronavirus. | 2011-06-16 |
20110142798 | HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 2011-06-16 |
20110142799 | MODULATION OF NEURODEGENERATIVE DISEASE BY MODULATING XBP-1 ACTIVITY - The invention provides methods for treating and preventing a neurodegenerative disease associated with aberrant protein aggregation by modulating the expression and/or activity of XBP-1, IRE-1 alpha, and/or EDEM. The present invention also pertains to methods for identifying compounds that modulate the expression and/or activity of XBP-1, 1RE-1 alpha, and/or EDEM. The present invention further provides methods for determining whether a subject is at risk of developing or has developed a neurodegenerative disease associated with aberrant protein aggregation. | 2011-06-16 |
20110142800 | METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEINS - This invention provides compositions comprising a protein, an absorption enhancer, a protease inhibitor, methods for treating diabetes mellitus, comprising administering same, and methods for oral administration of a protein with an enzymatic activity, comprising orally administering same. | 2011-06-16 |
20110142801 | PROTEASE RESISTANT MODIFIED INTERFERON-BETA POLYPEPTIDES AND THEIR USE IN TREATING DISEASES - Protease resistant modified interferon-beta polypeptides, pharmaceutical compositions and methods of treatment by administering the compositions are provided. The modified interferon-beta polypeptides are orally available; hence pharmaceutical compositions formulated for oral administration also are provided. | 2011-06-16 |
20110142802 | FUNGICIDAL COMPOSITIONS - A fungicidal composition suitable for control of disease caused by phytopathogens comprising (A) a compound of formula (I), wherein R | 2011-06-16 |
20110142803 | METHOD FOR TREATING INFLAMMATION ASSOCIATED WITH AMYLOID DEPOSITS AND BRAIN INFLAMMATION INVOLVING ACTIVATED MICROGLIA - Filamentous bacteriophage which does not display an antibody or a non-filamentous bacteriophage antigen on its surface is used to inhibit or treat brain inflammation associated with amyloid deposits and/or involving activated microglia, to inhibit the formation of amyloid deposits, and to disaggregate pre-formed amyloid deposits. | 2011-06-16 |
20110142804 | NANOFIBER SCAFFOLD - The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery. | 2011-06-16 |
20110142805 | METHOD OF RENAL REPAIR AND REGENERATION AND THE TREATMENT OF DIABETIC NEPHROPATHY - We have disclosed methods for treating chronic kidney disease. More specifically, we have disclosed methods for treating diabetic nephropathy with human kidney derived cells. | 2011-06-16 |
20110142806 | Electroactive Scaffold - A scaffold assembly and related methods of manufacturing and/or using the scaffold for stem cell culture and tissue engineering applications are disclosed which at least partially mimic a native biological environment by providing biochemical, topographical, mechanical and electrical cues by using an electroactive material. The assembly includes at least one layer of substantially aligned, electrospun polymer fiber having an operative connection for individual voltage application. A method of cell tissue engineering and/or stem cell differentiation uses the assembly seeded with a sample of cells suspended in cell culture media, incubates and applies voltage to one or more layers, and thus produces cells and/or a tissue construct. In another aspect, the invention provides a method of manufacturing the assembly including the steps of providing a first pre-electroded substrate surface; electrospinning a first substantially aligned polymer fiber layer onto the first surface; providing a second pre-electroded substrate surface; electrospinning a second substantially aligned polymer fiber layer onto the second surface; and, retaining together the layered surfaces with a clamp and/or an adhesive compound. | 2011-06-16 |
20110142807 | Mesenchymal Stem Cells and Uses Therefor - Methods of treating autoimmune diseases, allergic responses, cancer, or inflammatory diseases in an animal, promoting would healing, and promoting angiogenesis in an organ or tissue of an animal by administering to the animal mesenchymal stem cells in an effective amount. | 2011-06-16 |
20110142808 | Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells - Solutions and suspensions comprising polymerized hemoglobin derived from human blood are disclosed. The solutions and suspensions may comprise cell culture medium, an enzyme (such as a protease), and/or a buffer. Processes of preparing the solutions and suspensions are also disclosed. The solutions and suspensions may be employed in methods of isolating mammalian cells, such as pancreatic islets, methods of preserving mammalian tissue and organs, methods of aiding the recovery of mammalian cells following their isolation, methods of maintaining mammalian cells, methods of propagating mammalian cells, and methods of treating a mammal with diabetes. | 2011-06-16 |
20110142809 | METHOD FOR SEPARATING HIGHLY ACTIVE STEM CELLS FROM HUMAN STEM CELLS AND HIGHLY ACTIVE STEM CELLS SEPARATED THEREBY - The present invention relates to a method for separating highly active stem cells from human stem cells, the highly active stem cells separated by the method, a cell therapeutic agent containing the stem cells, and a medium for separating the highly active stem cells from stem cells containing a specific cytokine. According to the present invention, the method is useful for separating the highly efficient stem cells from mesenchymal stem cells of various origins. Further, the method is very useful in developing a cell therapeutic agent of high efficiency because the method can be applicable to stem cells of various origins which are cultured under different conditions. Senescent stem cells increased by several passage times in vitro can be effectively sorted out, so the method can be used for reactivating the stem cells. | 2011-06-16 |
20110142810 | CELL PREPARATION FOR BONE TISSUE REGENERATION - The present invention provides a cell preparation that can be prepared from cells collected from a patient of any age group, and that has an excellent bone tissue regenerative capacity and is effective for bone tissue regeneration. Undifferentiated osteoblasts obtained from alveolar bone, particularly those obtained by being cultured after the enzyme treatment of alveolar bone have a remarkable bone tissue regenerative capacity, and are therefore useful for a cell preparation for bone tissue regeneration. | 2011-06-16 |
20110142811 | MEASLES VIRUS FOR THE ELIMINATION OF UNWANTED CELL POPULATIONS - The present invention concerns recombinant measles virus as a therapeutic, in particular a recombinant measles virus comprising a suicide gene in its genome, a mutated viral hemagglutinin, and a specificity domain specifically recognizing a cancer antigen. Furthermore, it relates to a polynucleotide coding for such a recombinant measles virus and a vector comprising said polynucleotide. The current invention also relates to a method for the manufacture of and a medicament comprising said recombinant measles virus, as well as a method for treating a solid tumor using said recombinant measles virus. | 2011-06-16 |
20110142812 | SUPPRESSIVE MACROPHAGES, C-REACTIVE PROTEIN AND THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND IMMUNE THROMBOCYTOPENIC PURPURA - The present invention relates to the use of suppressive macrophage or dendritic cells (activated with C-reactive protein or CRP-related compounds), for the treatment of various disease states and conditions associated with immune thrombocytopenic purpura (ITP) and/or systemic lupus erythematosus (SLE), including lupus of the skin (discoid), systemic lupus of the joints, lungs and kidneys, hematological conditions including hemolytic anemia and low lymphocyte counts, lymphadenopathy and CNS effects, including memory loss, seizures and psychosis, among numerous others as otherwise disclosed herein. In another aspect of the invention, the reduction in the likelihood that a patient who is at risk for an outbreak of a disease state or condition associated with systemic lupus erythematosus or ITP will have an outbreak is an additional aspect of the present invention. In the case of ITP, methods of the present invention are used to increase platelet counts in the treated patient. In addition, in the case of ITP, the present invention relates to the use of CRP or a CRP-related compound in the absence of suppressive macrophages for the treatment of ITP. | 2011-06-16 |
20110142813 | Use Of Anti-Cancer Cell Composition For Treatment Of Head And Neck Cancer, Which Is Intended To Be Administered To Nutrient Artery Of Tumor - To provide a method of efficiently delivering cells having an anti-tumor activity to tumor tissues to evoke a stronger anti-tumor reaction, and a method of providing a more effective tumor regression effect, both in a cellular immunotherapy for cancer utilizing cells having an anti-tumor activity or antigen presenting cells for activating cells capable of exhibiting an anti-tumor activity. Provided are: a method of treating head and neck cancer, comprising administering an anti-cancer cell composition containing NKT cells activated in vitro with an NKT cell ligand into the tumor-feeding artery, and administering an NKT cell-stimulating agent containing antigen presenting cells treated with an NKT cell ligand through the upper respiratory tract mucous membrane; a use, in anti-cancer treatment of head and neck region, of the anti-cancer cell composition and the NKT cell-stimulating agent; a kit comprising the anti-cancer cell composition and the NKT cell-stimulating agent; and the anti-cancer cell composition. | 2011-06-16 |
20110142814 | Methods for Using Protein Kinase C-Theta Inhibitors in Adoptive Immunotherapy - The present invention provides methods for reducing tumor necrosis factor activation of regulatory T cells (Tregs), restoring the activity of defective Tregs, and enhancing the function of Tregs using Protein Kinase C theta (PKC-θ) inhibitors. The enhancement in Treg function is of use in facilitating adoptive immunotherapy in the treatment of immunological disorders. | 2011-06-16 |
20110142815 | COMPOUNDS, COMPOSITION, METHODS, TARGETS FOR CANCER THERAPY - This invention describes methods and pharmaceutical compositions for combinational cancer treatments that are capable of inducing JNK phosphorylation and induce programmed cell death. It also identified genes as target for anti-cancer drug development and enhancement of the chemotherapeutic drug effect for the treatment of cancer. This invention points to a novel method and principle for a new avenue of developing more efficient and low or non cytotoxic cancer treatment. | 2011-06-16 |