25th week of 2009 patent applcation highlights part 52 |
Patent application number | Title | Published |
20090156591 | Thiophene and Thiazole Substituted trifluoroethanone Derivatives as Histone Deacetylase (Hdac) Inhibitors - The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof. The compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases. | 2009-06-18 |
20090156592 | Fungicidal Azocyclic Amides - Disclosed are compounds of Formulae 1, 1A, 1B and 1C including all geometric and stereoisomers, N-oxides, and salts thereof, | 2009-06-18 |
20090156593 | Spirocyclic Azaindole Derivatives - The invention relates to substituted azaindole derivatives, to methods for the production thereof, to medicaments containing said compounds and to the use of substituted azaindole derivatives for producing medicaments. | 2009-06-18 |
20090156594 | HETEROCYCLIC KINASE MODULATORS - The present disclosure provides heterocyclic protein kinase modulators and methods of using these compounds to treat diseases mediated by kinase activity. | 2009-06-18 |
20090156595 | Pteridines useful as HCV inhibitors and methods for the preparation thereof - The present invention relates to the use of pteridines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to compounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceutical compositions comprising them, and combinations of said compounds with other anti-HCV agents. | 2009-06-18 |
20090156596 | Unsaturated Heterocyclic Derivatives - This invention relates to compounds of the general formula: | 2009-06-18 |
20090156597 | Novel Compounds - Novel substituted 2,4,8-trisubstituted 8H-pyrido[2,3-d]pyrimidin-7-one containing compounds and compositions, and their use in therapy as CSBP/RK/p38 kinase inhibitors. | 2009-06-18 |
20090156598 | Imidazolopyrimidine modulators of TRPV1 - Certain TRPV1-modulating imidazolopyrimidine compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPV1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease. | 2009-06-18 |
20090156599 | Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1 - Certain TRPV1-modulating imidazolo-, oxazolo-, and thiazolopyrimdine compounds are described. The compounds may be used in pharmaceutical compositions and methods for treating disease states, disorders, and conditions mediated by TRPV1 activity, such as pain, arthritis, itch, cough, asthma, or inflammatory bowel disease. | 2009-06-18 |
20090156600 | Quinolines and Their Therapeutic Use - Compounds of formula [1] are CRTH2 antagonists, useful in the treatment of conditions having an inflammatory component; in which: R | 2009-06-18 |
20090156601 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER - The invention provides compounds which are pyrimidines of formula (I): wherein —XR | 2009-06-18 |
20090156602 | Organic Compounds - The invention provides a pharmaceutical combination comprising:
| 2009-06-18 |
20090156603 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS - Provided are compounds of formula I that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes meilitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase. | 2009-06-18 |
20090156604 | FUSED BICYCLIC IMIDAZOLES - Compounds of formula (I) | 2009-06-18 |
20090156605 | Quinolones and azaquinolones that inhbit prolyl hydroxylase - Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: | 2009-06-18 |
20090156606 | OPTICAL CORRECTION - The present disclosure describes compositions which improve visual acuity and to methods for their use. | 2009-06-18 |
20090156607 | 2-OXO-1-PYRROLIDINE DERIVATIVES - The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals. | 2009-06-18 |
20090156608 | Pyridazine Compound and Use Thereof - A pyridazine compound of the formula: | 2009-06-18 |
20090156609 | TREATMENT OF POST-TRAUMATIC STRESS DISORDER WITH TETRAHYDROINDOLONE ARYLPIPERZAINE COMPOUNDS - Tetrahydroindolone and aryl piperazine derivatives for use in treating post-traumatic stress disorder and acute stress disorder. | 2009-06-18 |
20090156610 | Spiroindolinone Derivatives - There are provided compounds of the formula | 2009-06-18 |
20090156611 | MAMMALIAN HEDGEHOG SIGNALING MODULATORS - The disclosure relates to compositions for and methods of inhibiting the mammalian Hedgehog signaling pathway. | 2009-06-18 |
20090156612 | Substituted imidazole compound and use thereof - The present invention relates to a compound represented by the formula: | 2009-06-18 |
20090156613 | Bicyclic heteroaryl-substituted imidazoles as modulators of the histamine H4 receptor - Bicyclic heteroaryl-substituted imidazole compounds are described, which are useful as H | 2009-06-18 |
20090156614 | Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof - This invention provides new compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, prostate cancer, muscle wasting diseases and/or disorders or a bone-related diseases and/or disorders. | 2009-06-18 |
20090156615 | ORGANIC COMPOUNDS - The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed. | 2009-06-18 |
20090156616 | THERAPEUTIC AGENTS - The present invention relates to compounds of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, to methods for their therapeutic use and to pharmaceutical compositions containing them. | 2009-06-18 |
20090156617 | Tyrosine kinase inhibitors - The present invention relates to imidazo[1,2-a]pyrimidine derivatives, that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 2009-06-18 |
20090156618 | 1-(1- (2-Ethoxyethyl)-3-Ethyl-7-(4-Methylpyridin-2-Ylamino) - 1H-Pyrazolo [4,3-D] Pyrimidin-5-YL) Piperidine-4-Carboxylic acid and salts thereof - The present invention comprises 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid and its salts. The invention further comprises pharmaceutical compositions, methods of treatment, and synthetic methods relating to 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid and its salts. | 2009-06-18 |
20090156619 | Heterocycle Substituted Amide and Sulfur Amide Derivatives as Histone Deacetylase (HDAC) Inhibitors - The present invention related to compounds of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof. Compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Compounds of the present invention are useful for treating or preventing neurodegenerative diseases, schizophrenia and stroke among other diseases. | 2009-06-18 |
20090156620 | [4-(6-FLUORO-7-METHYLAMINO-2,4-DIOXO-1,4-DIHYDRO-2H-QUINAZOLIN-3-YL)-PHENY- L]-5-CHLORO-THIOPHEN-2-YL-SULFONYLUREA SALTS, FORMS AND METHODS RELATED THERETO - The present invention provides novel sulfonylurea salts of a salt of formula (I) | 2009-06-18 |
20090156621 | HCV INHIBITORS - The present invention relates to compounds that are useful in the treatment of viruses belonging to Flaviviridae, including flaviviruses, pestiviruses, and hepaciviruses. The invention includes compounds useful for the treatment or prophylaxis of dengue fever, yellow fever, West Nile virus, and HCV. | 2009-06-18 |
20090156622 | 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES - The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades. | 2009-06-18 |
20090156623 | N-ARYL PIPERIDINE SUBSTITUTED BIPHENYLCARBOXAMIDES - N-aryl piperidine substituted biphenylcarboxamides compounds of formula (I) | 2009-06-18 |
20090156624 | Methionine aminopeptidase-2 inhibitors and methods of use thereof - The present invention provides methods of parasitic infections, thymoma, and lymphoid malignancies in a subject by administering to the subject a therapeutically effective amount of one or more of the compounds of the invention. | 2009-06-18 |
20090156625 | Novel Use of a Nicotinic Receptor Agonist 156 - The invention relates to a novel method of treatment or prophylaxis of osteoarthritis, which comprises administering to a patient in need thereof a therapeutically effective amount of an alpha 7 nicotinic AcetylCholine receptor agonist of Formula (I), or a pharmaceutically acceptable salt thereof: | 2009-06-18 |
20090156626 | Process for Preparing Spirocyclic Cyclohexane Compounds and Methods of Using Such Compounds - Spirocyclic cyclohexane compounds corresponding to formula I | 2009-06-18 |
20090156627 | THERAPEUTIC COMPOUNDS - The invention provides compounds of formula I: | 2009-06-18 |
20090156628 | Aminothiazoles and their Uses - The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases particularly bacterial infections. | 2009-06-18 |
20090156629 | INDENOISOQUINOLINE-RELEASABLE POLYMER CONJUGATES - The present invention provides releasably-linked indenoisoquinoline polymer conjugates. Methods of making the conjugates and methods of treating mammals using the same are also disclosed. | 2009-06-18 |
20090156630 | ANTI-TUMOUR POLYCYCLIC CARBOXAMIDES - This invention relates to polycyclic carboxamide compounds of the formula I: | 2009-06-18 |
20090156631 | Controlled Release Compositions Containing Zolpidem - The present invention relates to controlled release compositions of Zolpidem or pharmaceutically acceptable salts thereof adapted to release Zolpidem over a predetermined time period, according to a monophasic and/or a biphasic profile of dissolution. The present invention also relates to monolithic matrix based formulations of Zolpidem or pharmaceutically acceptable salts thereof. | 2009-06-18 |
20090156632 | DOSAGE REGIMEN FOR PRASUGREL - A dosage regimen for treating vascular disease in a human comprising the steps of administering a loading dosage of about 30 mg to 70 mg of loading dose of prasugrel or a pharmaceutically acceptable salt thereof, and thereafter administering a daily dosage regimen of about 7.5 mg to 15 mg maintenance dose of prasugrel or a pharmaceutically acceptable salt thereof. | 2009-06-18 |
20090156633 | Heterocyclic quinolone derivatives that inhbit prolyl hydroxylase activity - Compounds of Formula I are useful inhibitors of HIF prolyl hydroxylases. Compounds of Formula I have the following structure: | 2009-06-18 |
20090156634 | Tropane alkaloids and trigonelline combinations and methods for administering the same - A nutritional composition comprising at least an effective amount of trigonelline or derivative of trigonelline and an effective amount of tropane alkaloids, wherein the ingredients act substantially simultaneously improve the consistency of muscular contractions with respect to applied force and relaxation cycles over time and reduce the onset of central fatigue. A method of same is also provided. | 2009-06-18 |
20090156635 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS - The present invention relates to compounds of formula (I) | 2009-06-18 |
20090156636 | THERAPEUTIC AGENT FOR GLOMERULAR DISEASE - The present invention relates to a preventive and/or therapeutic agent for a glomerular disease containing, as active ingredients pitavastatin or a salt thereof and candesartan cilexetil or a salt thereof. The agent of the present invention exhibits an excellent effect in the prevention and/or therapy of a glomerular disease. | 2009-06-18 |
20090156637 | BUTYROPHENONES AND SIGMA-1 RECEPTOR ANTAGONISTS PROTECT AGAINST OXIDATIVE-STRESS - The present invention includes compositions and methods for the protection of one or more central nervous system cells from trauma, when administered before, during or after the trauma, wherein the composition includes an effective amount of a butyrophenone, e.g., a 1-linked phenyl butyrophenone that is electronegative along the butyl chain and/or a Sigma-1 receptor antagonist. | 2009-06-18 |
20090156639 | COMPOSITIONS AND METHODS OF TREATMENT USING L-TYPE CALCIUM CHANNEL BLOCKERS AND CHOLINESTERASE INHIBITORS - The present invention relates to composition comprising at least one L-type calcium channel blocker, particularly the compound (+)-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)-1,4-dihydro-2,6-dimethyl-pyridine-3,5-dicarboxylate, in combination with at least one cholinesterase inhibitor, particularly donepezil, and uses thereof in methods of treatment. | 2009-06-18 |
20090156640 | NOCICEPTIN ANALOGS - A compound of the formula (I), (II), (III) or (IV) | 2009-06-18 |
20090156641 | INHIBITION OF CYCLOOXYGENASE-2 ACTIVITY - The present invention provides new methods for inhibiting the activity of the enzyme cycloxygenase-2 (or COX-2). Inhibitors of COX-2 are known to be useful anti-inflammatory, analgesic and anti-angiogenic agents. The compounds in the present case are heterocyclic substituted 4-aminoglutarimides. Methods of using the compounds to inhibit prostaglandin synthesis are claimed. | 2009-06-18 |
20090156642 | 5-Membered heterocyclic compound - The present invention provides 5-membered heterocycle compounds represented by the following general formula (I): | 2009-06-18 |
20090156643 | Substituted isoxazoline compound and pesticide - There is provided a novel pesticide, particularly an insecticide or an acaricide. A substituted isoxazoline compound of formula (1) or a salt thereof: | 2009-06-18 |
20090156644 | Use of thiazole derivatives and analogues in the treatment of cancer -
There is provided a use of a compound of formula (I), wherein X, Y, T, W, A | 2009-06-18 |
20090156645 | Method for Increasing the Susceptibility of Peptide Deformylase Inhibitors by Using Efflux Pump Inhibitors - The present invention provides methods and compositions for increasing the susceptibility of PDF inhibitors against Gram-negative organisms by using efflux pump inhibitors. | 2009-06-18 |
20090156646 | PYRIDYLPHENOL COMPOUND AND USE THEREOF - The present invention provides a compound which has metastin receptor antagonist activity and is useful for preventing and treating hormone-dependent cancer, benign prostatomegaly, endometriosis, precocious puberty, uterine myoma or the like. More specifically, the present invention provides a compound, represented by the formula: | 2009-06-18 |
20090156647 | Method for maintaining physiological pH levels during intensive physical exercise - A nutritional supplement comprising at least a therapeutically effective amount of pyridoxine α-hydroxyisocaproate is provided by the present invention. The ingredients of the present nutritional supplement act substantially simultaneously to maintain physiological blood and muscular pH and increase the time to muscular fatigue in a mammal during periods of repetitive forceful muscular exercise. A method of use is provided by the present disclosure. | 2009-06-18 |
20090156648 | Preparations containing pyridoxine and alpha-hydroxyisocaproic acid (HICA) - The present invention relates to stable salts of pyridoxine and α-hydroxyisocaproic acid (HICA) endowed with enhanced nutritional and/or therapeutical efficacy in respect to their individual effects and to solid compositions containing such salts, particularly suited to oral administration. A method of preparation is also provided. | 2009-06-18 |
20090156649 | Cellular phosphorylation potential enhancing compositions preparation and use thereof - A pharmaceutical composition comprising as an active phosphorylation potential enhancing substance a pharmaceutically-acceptable salt of an alpha-keto carboxylic acid thereof alone or in combination with nicatinamide and creatine and, its use and products containing the same. | 2009-06-18 |
20090156650 | COMPOSITION THAT COMPRISES AT LEAST ONE OXIME AND ITS USE IN THERAPEUTICS - This invention relates to a medication, a pharmaceutical composition. and method for the treatment of respiratory poisoning in animals and humans caused by organophosphorus compounds, whereby said medication and said pharmaceutical composition comprise at least one oxime and one blocker of organic cation transporters (OCT). | 2009-06-18 |
20090156651 | Heterocyclylethylbenzamide Derivatives - A compound of general formula (I): | 2009-06-18 |
20090156652 | THERAPEUTIC AGENT FOR FOOD COMPETENCE DISORDER IN STOMACH - A therapeutic agent for impaired gastric accommodation which contains as an active ingredient a compound represented by the general formula (1): | 2009-06-18 |
20090156653 | Amino alcohol derivatives, salts thereof and immunosuppresive agents - An amino alcohol derivative represented by the following general formula (1) (for example, (±)-2-amino-5-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-2-methylpentane- | 2009-06-18 |
20090156654 | DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS - This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against | 2009-06-18 |
20090156655 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES - The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like. | 2009-06-18 |
20090156656 | USE OF LIGHT-ACTIVE INDOCYANINE GREEN FOR TREATING INFLAMMATORY DISORDERS IN THE ORAL CAVITY - In a process for treating disorders, especially inflammatory disorders, in the oral cavity, by introducing a substance activable by a light source, the substance comprises the active ingredient indocyanine green and the spectrum of the light source emits significant proportions in the range of 700-1000 nm. | 2009-06-18 |
20090156657 | ANTI-INFLAMMATORY COMPOSITION - The present invention provides a method of improving or preventing various conditions through suppression of the expression of inflammatory cytokines based on the action mechanism of suppression of NF-κB activation. The present invention provides a composition for suppressing NF-κB activation, containing a serotonin derivative such as feruloyl serotonin (N-feruloyl serotonin) and p-coumaroyl serotonin (N-(p-coumaroyl)serotonin), a composition for suppressing the expression of VCAM-1 and/or MCP-1 via NF-κB, containing the serotonin derivative and an anti-inflammatory composition containing the serotonin derivative. The composition of the present invention can be used as a pharmaceutical agent or a food. | 2009-06-18 |
20090156658 | Antioxidant-Containing Food Composition For Use In Inhibiting Histamine Pathways In Companion Animals - The invention encompasses compositions for inhibiting histamine release pathways in a companion animal, for example, felines and in treating or preventing idiopathic cystitis or interstitial cystitis. The compositions of the invention include an amount of lipoic acid that is effective in inhibiting histamine release pathways in a companion animal, for example, felines and in treating or preventing idiopathic cystitis or interstitial cystitis. | 2009-06-18 |
20090156659 | SYSTEM AND METHOD FOR COLLECTING, STORING, PROCESSING, TRANSMITTING AND PRESENTING VERY LOW AMPLITUDE SIGNALS - A method and apparatus for producing an effect of a chemical or biochemical agent on a system responsive to such agent, are disclosed. In practicing the method, a plurality of low-frequency time-domain signals of the agent are generated, each at a different at a different noise level within a selected noise level range. The signals are analyzed by producing spectral plots of the time-domain signals, and identifying an optimized agent-specific time-domain signal based on information in the spectral plots. A chemical or biological system responsive to the agent is exposed to the optimized time-domain signal by placing the system within the magnetic field of an electromagnetic transducer, and applying the signal to the transducer at a signal amplitude and for a period sufficient to produce in the system an agent-specific effect on the system. | 2009-06-18 |
20090156660 | PHARMACEUTICAL COMPOSITION CONTAINING TAXANE DERIVATIVE DESTINED FOR THE PREPARATION OF AN INFUSION SOLUTION, METHOD OF PREPARATION THEREOF AND USE THEREOF - A pharmaceutical composition containing a taxane derivative, destined for the preparation of an infusion solution for administration to patients, containing a concentrate consisting of a pharmaceutically effective amount of docetaxel, a suitable solvent, which is preferably ethanol, a surfactant, which is polysorbate 80 and a pharmaceutically effective amount of an appropriate buffer; and optionally a co-solvent, consisting of an aqueous solution of a pharmaceutically effective amount of polysorbate 80 and optionally suitable organic solvent and/or a pharmaceutically effective amount of an appropriate buffer. This composition shows an excellent chemical and physical stability. The invention includes also a method of preparation of the pharmaceutical composition and the use thereof. | 2009-06-18 |
20090156661 | Compositions and Methods for Treatment and Prevention of Metabolic Syndrome and its Associated Conditions with Combinations of Flavonoids, Liminoids and Tocotrienols - The present invention is directed to compositions and methods for the treatment and/or prevention of metabolic syndrome and its associated conditions, such as insulin resistance, which involve using a combination composition of limonoids, flavonoids and tocotrienols. | 2009-06-18 |
20090156662 | Fat Absorption Inhibitor - Disclosed is a composition or beverage/food for inhibiting the fat absorption, which is derived from a natural material and therefore is safe, and which can be ingested continuously. The composition or beverage/food comprises the following components: (A) theaflavine monogallate; (B) theaflavine; (C) theaflavine digallate; and (D) polyphenol, wherein these components satisfy the following requirements: (1) a weight-based content ratio [(A)/(B)] is 0.4-100%; (2) the weight of the component (A) is larger that that of the component (C); and (3) a weight-based content ratio [A)/(D)] is 0.01-1.0%. The composition or beverage/food can be used for the prevention or treatment of a disease such as arteriosclerosis and an ischemic heart disease (e.g., angina pectoris, myocardial infarction). | 2009-06-18 |
20090156663 | Functional Foods Comprising Flavonoids and Tocotrienols and Methods Thereof - Disclosed in certain embodiments is a functional food comprising an active agent combination comprising flavonoids and tocotrienols. | 2009-06-18 |
20090156664 | Natural Vitamin E Compositions with Superior Antioxidant Potency - Compositions for increased antioxidant potency of natural vitamin E (d-alpha-tocopherol), comprising alpha-, beta-, delta-, and gamma-forms of tocopherols and tocotrienols are disclosed. All of these compositions provide 400 International Units (IU), based on one mg of d-alpha-tocopherol provides 1.49 IU. These compositions showed antioxidant activities superior to natural d-alpha-tocopherol. These compositions are designed to provide protection of the cell membrane lipid layer, and protection against heart disease, cancer, and eye disease. | 2009-06-18 |
20090156665 | Compositions Comprising Flavonoids and Toctrienols and Methods Thereof - Disclosed in certain embodiments is a pharmaceutical formulation comprising a pharmaceutical ingredient comprising an active agent combination comprising flavonoids and tocotrienols in a ratio of about 75:25 to about 95:5 and at least one pharmaceutically acceptable excipient. | 2009-06-18 |
20090156666 | NOVEL COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS - The present invention relates to novel compositions comprising magnolol and/or honokiol and glucosamine as well as to the use of these compositions as a medicament, in particular as a medicament for the treatment, co-treatment or prevention of inflammatory disorders. | 2009-06-18 |
20090156667 | METHOD OF TREATING ASTHMA, ALLERGIC RHINITIS, AND SKIN DISORDERS - The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis. | 2009-06-18 |
20090156668 | Ginkgolide Compounds, Compositions, And Extracts, And Uses Thereof - The present invention relates to Ginkgolide derivatives, compositions and extracts comprising one or more Ginkgolides and/or derivatives thereof and methods of use of the compositions to treat neurological disorders and as imaging agents. | 2009-06-18 |
20090156669 | COMBINATION OF ACTIVE INGREDIENTS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES - The novel active compound combination of spiromesifen and gamma-cyhalothrin has very good insecticidal and acaricidal properties. | 2009-06-18 |
20090156670 | NONAQUEOUS LIQUID PARENTERAL ACECLOFENAC FORMULATION - A nonaqueous liquid parenterally deliverable pharmaceutical formulation, and more particularly a nonaqueous liquid parenteral Aceclofenac formulation comprising the selective NSAID Aceclofenac, is disclosed. A process of preparing Aceclofenac formulation, the therapeutic dosage form and storage of dose, and the method of treating a subject having a condition or a disorder wherein treatment with NSAID is indicated, are also disclosed. Diclofenac formed by conversion of Aceclofenac is solubilized by the nonaqueous solubilizer(s), which are substantially inert with respect to such conversion. The composition has Aceclofenac salt stabilizing means for inhibiting precipitation of Aceclofenac. The compositions disclosed in the present invention are stable upon storage at room temperature and at refrigerated temperatures. Compositions disclosed in the present invention, whether ready-to-use or requiring dilution prior to administration, can be prepared by inexpensive processes disclosed herein. | 2009-06-18 |
20090156671 | DEUTERIUM-ENRICHED OXYBUTYNIN - The present application describes deuterium-enriched oxybutynin, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 2009-06-18 |
20090156672 | Substituted Phenyl Aziridine Precursor Analogs as Modulators of Steroid Receptor Activities - Disclosed are methods and pharmaceutical compositions for modulating one or more steroidal receptor activities. The methods typically utilize and the pharmaceutical compositions typically include one or more substituted phenyl aziridine precursors, their respective aziridines, analogs thereof, derivatives thereof, or pharmaceutically acceptable salts thereof such as CpdA. The methods and compositions may be used for treating diseases, disorders, and conditions associated with glucocorticoid receptor activity, androgen receptor activity, or both, such as cancers, acne vulgaris, and alopecia. | 2009-06-18 |
20090156673 | ANTI-INFLAMMATORY ACTIONS OF NEUROPROTECTIN D1/PROTECTIN D1 AND IT'S NATURAL STEREOISOMERS - (Neuro)protectin D1 (1OR,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid) and 15,16-dehydro-PD1 and their derivatives are useful in the treatment of airway inflammation, especially asthma. | 2009-06-18 |
20090156674 | Valnemulin Salts with Organic Acids - The invention relates to the production of a new salt form of valnemulin, a compound of formula I, which is notable for its good crystallinity in higher purity, its simpler technical usability and improved storage stability. | 2009-06-18 |
20090156675 | COMPOSITION FOR PREVENTING THE OCCURRENCE OF CARDIOVASCULAR EVENT IN MULTIPLE RISK PATIENT - Disclosed is a composition which is useful for preventing the occurrence of a cardiovascular event, particularly a composition which is expected to show a prophylactic effect on a cardiovascular event occurring in a hypercholesterolemia patient despite providing the patient with a treatment with HMG-CoA RI or a cardiovascular event occurring in a multiple risk patient. | 2009-06-18 |
20090156676 | Organic salts of beta-alanine - The present invention relates to stable salts of β-alanine and an organic acid endowed with enhanced nutritional and/or therapeutical efficacy in respect to their individual effects and to solid compositions containing such salts, particularly suited to oral administration. A method of preparation is also provided. | 2009-06-18 |
20090156677 | Gabapentin-containing Solid Compositions and Process for Preparing the Same - The present invention provides a stabilized solid composition containing a 4-amino 3-substituted-butanoic acid derivative which can be obtained by incorporating a humectant as a stabilizer. | 2009-06-18 |
20090156678 | PROCESS FOR THE PRODUCTION OF 2-[4-(3- AND 2-FLUOROBENZYLOXY) BENZYLAMINO] PROPANAMIDES - A process for obtaining therapeutically active 2-[4-(3- and 2-(fluorobenzyloxy)benzylamino]propanamides and their salts with pharmaceutically acceptable acids with high purity degree, in particular, with a content of dibenzyl derivatives impurities lower than 0.03%, preferably lower than 0.01% by weight. | 2009-06-18 |
20090156679 | LEVODOPA PRODRUG MESYLATE, COMPOSITIONS THEREOF, AND USES THEREOF - (2R)-2-Phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided. | 2009-06-18 |
20090156680 | Deodorants Containing Aminoacid Derivatives - A deodorant composition comprising an aminoacid compound of formula I or II and a carrier material. I R | 2009-06-18 |
20090156681 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS - Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. | 2009-06-18 |
20090156682 | N-(1-Methyl-2Phenylethyl)Benzamide Derivatives - A compound of general formula (I): | 2009-06-18 |
20090156683 | FAST RELEASE SOLID FORMULATION, PREPARATION AND USE THEREOF - The present invention relates to a chemically stable formulation of florfenicol, (and structurally related compounds) in compositions such as soluble blended powders, granules, fast-dissolving tablets or pellets suitable for rapid release of the drug in water, and to methods and kits for treating animals with aqueous compositions including florfenicol. | 2009-06-18 |
20090156684 | LIQUID ANTIBACTERIAL COMPOSITIONS INCORPORATING TRICHLOROCARBANILIDE WITH REDUCED WATER ACTIVITY - A liquid antibacterial soap comprising trichlorocarbanilide, wherein the composition includes, 0.1-5 wt. % trichlorocarbanilide, 0-40 wt. % water, 0.1-40 wt. % of a surfactant or mixture of surfactants, 10-60 wt. % of lower glycols to render the composition visually clear and stable, and 0.1-10 wt. % of a mixture of additional adjuvant ingredients. | 2009-06-18 |
20090156685 | (R)-CHIRAL HALOGENATED SUBSTITUTED FUSED HETEROCYCLIC AMINO COMPOUNDS USEFUL FOR INHIBITING CHOLESTEROL ESTER TRANSFER PROTEIN ACTIVITY - The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Novel high yield, stereoselective processes for the preparation of the chiral substituted alkanol compounds from chiral and achiral intermediates are described. | 2009-06-18 |
20090156686 | Composition containing higher fatty acid derivative and foods and drinks - An object of the invention is to provide a composition containing a higher fatty acid derivative, which can be easily produced at low cost, is effective as an agent for prevention and treatment of osteoporosis induced by various factors such as diet, dietary restriction, etc., is highly safe, and can be used regularly; and foods and drinks comprising the composition, which is effective as an agent for prevention and treatment of osteoporosis induced by various factors such as diet, dietary restriction, etc., and suitable as foods and drinks for hospitals, healthy drinks or foods, feeds, etc. | 2009-06-18 |
20090156687 | Fab I and inhibition of apicomplexan parasites - Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases. | 2009-06-18 |
20090156688 | SUPPRESSANT OF TOXICITY INDUCED BY CANCER CHEMOTHERAPEUTIC AGENT AND COMPOSITION OF CANCER CHEMOTHERAPEUTIC AGENT CONTAINING THE SAME - Disclosed are a suppressant of toxicity such as hepatotoxicity and nephrotoxicity, induced by cancer chemotherapeutic agent, and a composition of cancer chemotherapeutic agent containing the suppressant. The suppressant of toxicity induced by a cancer chemotherapeutic agent contains xanthorrhizol as an active ingredient. Xanthorrhizol shows an excellent ability in suppressing ill effects generated by dosage of cancer chemotherapeutic agent, such as hepatotoxicity and nephrotoxicity. | 2009-06-18 |
20090156689 | METHOD OF ENHANCING BIOLOGICAL ACTIVITY OF PLANT EXTRACTS - The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions. | 2009-06-18 |
20090156690 | Deodorizing Exfoliator - Disclosed is a method of treating body odor by scrubbing onto the skin a mixture of salt, one or more humectants, and one or more essential oils, with the salt being a gritty solid component in suspension within the other components so that the mixture is a viscously heterogeneous composition, which feels gritty to the touch and which exfoliates and moisturizes the skin when the mixture is scrubbed onto the skin, where the scrubbing allows the humectant(s) to penetrate into the skin. After scrubbing, the mixture is rinsed off of the skin (particularly the salt) with water, leaving a portion of mixture (minus the salt) remaining on the skin to terminate any residual fungi or bacteria, and to continue inhibiting the growth of new fungi and bacteria, while giving the skin a fragrance. | 2009-06-18 |
20090156691 | CELL CULTURE CARRIER IMPLANTABLE IN VIVO - A cell cultivation carrier implantable in vivo having independent pore with opening of 100 μm-1000 μm on the surface thereof produced by neutralization•gellation of collagen acidic solution, said collagen acidic solution is preliminary prepared by passing through a filter of 10 μm or less pore size by 5-20 mg/mL concentration. Especially, a cell cultivation carrier implantable in vivo having sufficiently self-organized accumulation shape•structure obtained by carrying out said neutralization under directionally supplying of alkali. | 2009-06-18 |