28th week of 2015 patent applcation highlights part 8 |
Patent application number | Title | Published |
20150190526 | Activated Polyoxazolines and Conjugates and Compositions Comprising the Same - The present disclosure provides POZ derivatives having a range of active functional groups allowing conjugation of POZ derivatives to a variety of target molecules under a wide range of reaction conditions to produce a hydrolytically stable target molecule-POZ conjugate. Furthermore, the present disclosure provides novel methods of synthesis for the disclosed POZ derivatives and hydrolytically stable target molecule-POZ conjugates created using the disclosed terminally activated monofunctional POZ derivatives. In one embodiment, the POZ derivative is a terminally activated monofunctional POZ derivative. | 2015-07-09 |
20150190527 | BLADDER CANCER SPECIFIC LIGAND PEPTIDES - The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X | 2015-07-09 |
20150190528 | LIQUID FORMULATION OF LONG-ACTING INSULIN AND INSULINOTROPIC PEPTIDE - The present invention relates to a liquid formulation of a combination of long-acting insulin and insulinotropic peptide, comprising insulin which is a physiologically active peptide, insulinotropic peptide, and albumin-free stabilizer, wherein the stabilizer comprises a buffer, a sugar alcohol, a non-ionic surfactant, and an isotonic agent; and a method for preparing the liquid formulation. The liquid formulation of the present invention does not contain a human serum albumin and potentially toxic factors to the body, and thus it has excellent storage stability for insulin conjugate and insulinotropic peptide conjugate at high concentration, without a risk of viral contamination. | 2015-07-09 |
20150190529 | TARGETING MULTIPLE RECEPTORS ON A CELL SURFACE FOR SPECIFIC CELL TARGETING - A method of delivering a cargo agent into cytosol of a cell can include: providing the delivery system of one of the embodiments described herein having the first and second delivery platforms; and administering the delivery system to a cell so as to cause targeting of two features on the cell so as to: cause endocytosis of the first and second delivery platforms of the delivery system into a common endosome, destabilize the endosome of the cell having the delivery system, release the cargo agent from the second linker; and release the cargo agent from the destabilized endosome into cytosol of the cell. A method of treating a disease can include: performing the method of method of delivering a cargo agent into cytosol of a cell in a subject having a disease, wherein the cargo agent is a therapeutic agent for the disease. | 2015-07-09 |
20150190530 | FUNCTIONALIZED LIPOSOMES USEFUL FOR THE DELIVERY OF BIOACTIVE COMPOUNDS - The invention relates to conjugates in which a sterol is functionalized by an ether bond with a water-soluble polymer to which a guiding ligand is bound. These conjugates improve the physico-chemical and delivery properties of their carrying vesicles, making these more stable, homogeneous and effective. A method for their preparation, a pharmaceutical composition containing said liposomes, and their therapeutic use are described as well. | 2015-07-09 |
20150190531 | NANOPARTICLE DELIVERY SYSTEM FOR TARGETED ANTI-OBESITY TREATMENT - A magnetic nanoparticles including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical can include a core region having a magnetic nanoparticle (MNPs) and a TRPV1 protein agonist. Further, an exterior coating comprising a polymer can be formed around the core region. The magnetically responsive pharmaceutical can be administered to a recipient and directed to a target region using an external magnetic field. | 2015-07-09 |
20150190532 | SMOOTH MUSCLE SPECIFIC INHIBITION FOR ANTI-RESTENOTIC THERAPY - The present invention provides for the incorporation of target sequences of microRNAs into the 3′ UTR region of a gene of interest in nucleic acid vectors. The invention also provides for an expression system comprising such vectors, a pharmaceutical composition comprising such vectors, as well as methods of treating or preventing cardiovascular disease by using such vectors. | 2015-07-09 |
20150190533 | X-RAY IMAGING CONTRAST MEDIA WITH LOW IODINE CONCENTRATION AND X-RAY IMAGING PROCESS - The present invention relates to X-ray examinations and to the improvement of patient safety during such. More specifically the invention relates to X-ray diagnostic compositions having low concentrations of iodine and an optimized amount of electrolytes. The invention further relates to methods of X-ray examinations wherein a body is administered with an X-ray diagnostic composition comprising a low concentration of iodine and irradiated with a radiation dose. | 2015-07-09 |
20150190534 | COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS - The present invention relates generally to compounds according to formula I that bind more specifically to mutated androgen receptors than to the wild type androgen receptors and therefore are useful as imaging agents for positron emission tomography (PET) used in the diagnosis and monitoring of prostate cancer. | 2015-07-09 |
20150190535 | SYSTEMS, METHODS, AND DEVICES FOR STERILIZING ANTISEPTIC SOLUTIONS - A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85° C. to about 135° C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%. | 2015-07-09 |
20150190536 | SYSTEMS, METHODS, AND DEVICES FOR STERILIZING ANTISEPTIC SOLUTIONS - A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85° C. to about 135° C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%. | 2015-07-09 |
20150190537 | Sanitizing Apparatus - The present disclosure presents sanitization devices and methods. More particularly, the disclosure presents devices and methods that significantly reduce or eliminate the activity of germs, bacteria and/or other infectious microorganisms from objects such as TV remotes, cell phones, electronic devices and personal and other handheld devices. The devices and methods use a pre-cleaning component to substantially remove radiation blocking debris allowing the germicidal radiation to exposes areas of the object that would not be exposed if the debris had not been removed allowing for improved sanitization. | 2015-07-09 |
20150190538 | Sanitizing Systems and Methods - Systems and methods for disinfecting/sanitizing various articles using disinfecting solutions and ultraviolet (UV) light. In one embodiment, an exemplary system includes a tank that contains a sanitizing liquid, coupled to a pipe system that includes multiple spray nozzles. A pump pumps the sanitizing liquid from the tank to the nozzles, which dispense the liquid to a disinfecting area. Some or all of the system may be mounted on a transportable mobile unit such as a trailer. In one embodiment, a portion including the tank and pump are mounted on the mobile unit and are connectable to a pipe system and nozzles that are permanently installed in a disinfecting area, such as the interior of a vehicle. Other embodiments are also possible. | 2015-07-09 |
20150190539 | INSTRUMENT DISINFECTION QUALITY METHODS AND DEVICES - Devices and methods for defining a data set, referred to herein as a signature, for a particular device having interior channels. A baseline signature is established for the particular device while the particular device is known to be in a decontaminated condition. After use of the device and subsequent decontamination of the device, a signature for the particular device is determined and compared with the baseline signature to verify that the latter signature is within an acceptable range. | 2015-07-09 |
20150190540 | Ultraviolet Discharge Lamp Apparatuses with One or More Reflectors - Apparatuses are disclosed which include a discharge lamp configured to emit ultraviolet light, a power circuit configured to operate the discharge lamp, and a reflector system configured to redirect ultraviolet light emitted from the discharge lamp. In some embodiments, the apparatuses include a support structure containing the power circuit and supporting the discharge lamp. In some of such embodiments, the reflector system is configured to redirect ultraviolet light propagating away from the support structure to a region exterior to the apparatus and which is between approximately 2 feet and approximately 4 feet from a floor of a room in which the apparatus is arranged. In other embodiments, the reflector system may be additionally or alternatively configured to redirect ultraviolet light propagating away from the support structure to encircle an exterior surface of the apparatus. In any case, the reflector system may, in some embodiments, include a repositionable reflector. | 2015-07-09 |
20150190541 | MEDICAL INSTRUMENT STERILIZATION METHOD AND STERILIZATION CONTROL DEVICE - A sterilization method for a medical instrument housed in a housing container includes a temperature-increasing step of housing the housing container in the autoclave and introducing high pressure steam into the autoclave to increase a temperature within the autoclave to a prescribed temperature, a cover sheet being thermally bonded to a peripheral wall portion of the container main body; a sterilizing step of holding the temperature within the autoclave at the prescribed temperature for a prescribed time to sterilize a medical instrument; and a cooling step of reducing the temperature within the autoclave. In the temperature-increasing step, the sterilizing step, and the cooling step, compressed gas is introduced into the autoclave under a steam atmosphere obtained by the introduction of the high pressure steam to increase a current pressure in the autoclave to higher than or equal to a pressure in the housing container and inhibit the cover sheet from peeling from the peripheral wall portion. | 2015-07-09 |
20150190542 | FRAGRANCE DIFFUSION DEVICE WITH A MULTITUDE OF OPENINGS - A fragrance diffusion device includes:
| 2015-07-09 |
20150190543 | COFORM NANOFIBROUS SUPERABSORBENT MATERIALS - A fibrous super absorbent material is disclosed including a) a hydrophilic three-dimensional fibrous web consisting of a first population of fibrillated nanofibers, and a second population of fibrillated microfibers, both populations uniformly distributed throughout the three-dimensional fibrous web where the first population comprises at least 50% of the total fiber population and b) a population of superabsorbent polymer (SAP) particles with a median size of less than 40 microns dispersed throughout the fibrous web. In various embodiments, a plurality of coarse (greater than 40 microns in diameter), fine from about (40 μm to about 10 μm in diameter), ultrafine (from about 10 μm to about one μm in diameter) and nanosize (less than one μm in diameter) particles are dispersed into the fibrous structure to absorb liquids or remove contaminants or bacteria from the fluids. | 2015-07-09 |
20150190544 | SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION - Provided herein are pre-formulations forming a biocompatible hydrogel polymer comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally a therapeutic agent and/or viscosity enhancer. In some embodiments, the biocompatible hydrogel polymer covers a wound in a mammal and adheres to the surrounding skin tissue. In other embodiments, the hydrogel polymer is delivered into a joint space to treat joint disease or navicular disease. | 2015-07-09 |
20150190545 | SPATIAL CONTROL OF ADDITIVES BY HIGH TEMPERATURE - Provided is a method of making a polymeric material with a spatially controlled distribution of one or more additives including the steps of blending the one or more additives with a polymeric material, consolidating the polymeric material, heating at least a portion of at least one surface of the consolidated additive-blended polymeric material, and cooling the heated consolidated additive-blended polymeric material, thereby forming a polymeric material with a spatially controlled distribution of additive. | 2015-07-09 |
20150190546 | THERAPEUTIC TRANSPLANTATION USING DEVELOPING, HUMAN OR PORCINE, RENAL OR HEPATIC, GRAFTS - A method of treating a renal, hepatic or enzyme-deficiency disorder in a subject in need thereof is disclosed. The method is effected by transplanting into the subject tissue derived from a human or porcine, kidney or liver, the kidney or liver being at a selected gestational stage. | 2015-07-09 |
20150190547 | BONE MATRIX COMPOSITIONS AND METHODS - An osteoinductive composition, corresponding osteoimplants, and methods for making the osteoinductive composition are disclosed. The osteoinductive composition comprises osteoinductive factors, such as may be extracted from demineralized bone, and a carrier. The osteoinductive composition is prepared by providing demineralized bone, extracting osteoinductive factors from the demineralized bone, and adding the extracted osteoinductive factors to a carrier. Further additives such as bioactive agents may be added to the osteoinductive composition. The carrier and osteoinductive factors may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, can induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. Also, in some embodiments, the osteoinductive composition can be used as a delivery device to administer bioactive agents. | 2015-07-09 |
20150190548 | IMPLANT AND METHOD FOR PRODUCING AN IMPLANT - The invention relates to an implant derived from intestinal tissue and to an improved method for producing an implant from intestinal tissue. According to the invention, intestinal tissue comprising a tubular segment of intestine with at least part of its associated vasculature intact is processed by: perfusing the vasculature through a vessel thereof with at least one decellularising medium; and separately perfusing the tubular segment of intestine through its lumen with at least one decellularising medium. The new method greatly improves tissue processing as compared with the methods previously known in the art, in which decellularisation solutions were perfused into the tissue via the vasculature only, relying on diffusion to decellularise and purify the small bowel tissue. In contrast, the invention provides for separate decellularisation and purification protocols for the vascular and tubular intestinal components, which are designed to optimise decellularisation and purification of each of these tissue structures while preserving certain tissue-specific three-dimensional structures. The resulting scaffold is substantially decellularised and provides an excellent implant for repair and regeneration of bowel tissue. | 2015-07-09 |
20150190549 | APPARATUS AND METHOD FOR PRODUCING A DENTAL BONE GRAFT - According to some embodiments of the invention, there is provided a method of producing a bone graft, comprising: providing a tooth, converting the tooth into a plurality of particles, and selecting from available particles a subset of particles. In some embodiments, the method is performed at a dental clinic. In some embodiments, the dental bone graft is an autograft produced by grinding a patient's tooth. According to some embodiments of the invention, there is provided an apparatus configured for connecting to a motor unit to produce a bone graft at a dental clinic, comprising: a housing encasing: a chamber sized to receive a tooth, a blade assembly positioned within the chamber and configured to pulverize the tooth, an accessible compartment in which a subset of tooth particles is collected, and one or more sieves positioned to sift particles that flow between the chamber and the accessible compartment. | 2015-07-09 |
20150190550 | Method for Producing a Dispersion Containing Silver Nanoparticles and Use of a Mixture Containing Silver Nanoparticles as a Coating Agent - A method for producing a dispersion containing silver nanoparticles, in particular for producing bone cement or a coating agent for implants from a silver salt. | 2015-07-09 |
20150190551 | PELLET-SHAPED COMPOSITION FOR MEDICAL USE, AND MOLDED PRODUCT - A problem that the present invention is to solve is to provide a pellet-shaped composition for medical use mainly comprising a polyvinyl chloride resin and exhibiting antithrombotic property when merely being molded. | 2015-07-09 |
20150190552 | AMORPHOUS METAL ALLOY MEDICAL DEVICES - This invention provides a new class of medical devices and implants comprising amorphous metal alloys. The medical devices and implants may be temporary or permanent and may comprise other materials as well, such as polymers, ceramics, and conventional crystalline or polycrystalline metal alloys. | 2015-07-09 |
20150190553 | EMBOLIC DEVICES - Described herein are apparatus, compositions, systems and methods for occluding vascular structures and vascular malformations with radiopaque hydrogel filaments. The filaments can contain no support members and can be CT and MR compatible. Methods of forming such filaments are also disclosed. | 2015-07-09 |
20150190554 | INJECTABLE HYDROGEL IMPLANT FOR TREATING GLAUCOMA - A method is provided for increasing the aqueous outflow of fluid through a trabecular meshwork and into a Schlemm's canal of an eye. A liquid hydrogel precursor solution is introduced into the Schlemm's canal, during a medical procedure. The liquid hydrogel precursor solution is crosslinked to form a water-permeable flexible semi-solid hydrogel in the Schlemm's canal, during the medical procedure. The hydrogel is left in the Schlemm's canal upon conclusion of the medical procedure. Other embodiments are also described. | 2015-07-09 |
20150190555 | Methods, Systems, and Devices Relating to Directional Eluting Implantable Medical Devices - Implantable medical devices may directionally elute a first therapeutic agent that promotes the growth of endothelial cells and a second therapeutic agent that inhibits the growth of smooth muscle cells. In some embodiments, implantable medical devices may elute a first therapeutic agent such as an anti-proliferative drug from an abluminal side of the implantable medical device and a second therapeutic agent such as an endothelialization agent from a luminal side of the implantable medical device. | 2015-07-09 |
20150190556 | DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES - The invention provides a medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The invention also provides a method of treating a narrowing in a body passageway comprising placing an implantable medical device comprising a hydrophobic analog of a medicament known to inhibit cell proliferation and migration. The medicaments can be incorporated within or coated on the device. The invention further provides hydrophobic analogs of medicaments known to inhibit cell proliferation and migration. | 2015-07-09 |
20150190557 | Suction Canister Cover - A suction canister cover is intended to hide the contents of a suction canister during a medical procedure from patients and other non-medical personnel who may become queasy at the sight of bodily fluids. The suction canister cover includes a base cover, a tubular lateral cover, an annular restraint, and a viewport. The base cover hides the bottom of the suction canister while the tubular lateral cover obscures the patients view through the sides of the suction canister. The annular restraint secures the suction canister cover to the suction canister to prevent the suction canister cover from being easily removed or sliding from the suction canister. The viewport allows medical personnel to view the volume of contents within the suction canister while keeping the contents blocked from patients and non-medical personnel. | 2015-07-09 |
20150190558 | METHOD AND DEVICE FOR INFUSION OF PHARMACOLOGIC AGENTS AND THROMBUS ASPIRATION IN ARTERY - A catheter device and method for treating an artery with thrombus, the catheter comprising an inflatable member. A carrier catheter has a proximal end and a distal end adapted to be inserted percutaneously into an artery, the carrier catheter having a tubular body adjacent to a rear end of the inflatable member. An inflating tube passes through the tubular body and having an open front end in fluid communication with the inflatable member to inflate same. An infusion tube is adapted to infuse pharmacologic agents, the infusion tube passing through the tubular body and having an open front end extending beyond the inflatable member. An aspiration tube is adapted to aspire the thrombus, the aspiration tube passing through the tubular body and having an open front end between the carrier catheter and the inflatable member. | 2015-07-09 |
20150190559 | WOUND HEALING SYSTEM USING POSITIVE PRESSURE TO PROMOTE GRANULATION AT A TISSUE SITE - A wound healing system for promoting healing of a wound of a patient includes a positive pressure source, a reduced pressure source, and a porous foam positioned in contact with the wound. The porous foam includes a plurality of flow channels in fluid communication with the reduced pressure source. The system further includes a filler member having a flexible wall defining an interior chamber. The interior chamber is in fluid communication with the positive pressure source, and a cover member is positioned over the filler member. | 2015-07-09 |
20150190560 | BREAST PUMP SYSTEM WITH ACTUATOR - The present application relates to a breast pump system comprising a vacuum pump, an actuator for driving the vacuum pump, and a power supply for supplying electrical power to a plurality of components including the actuator, and also to a method for use in such as system. An output voltage of the power supply is detected, and in response to the detected output voltage being less than a first threshold voltage, the supply of electrical power to a predetermined one of the plurality of components is suspended. Then, if the detected output voltage recovers to a level above a second threshold value, the supply of electrical power is resumed. | 2015-07-09 |
20150190561 | ENDOVASCULAR HEART ASSIST DEVICE - The invention is a next generation miniature heart assist device developed in order to maintain the blood circulation in patients with severe heart failure, and is applied endovascularly to the large arteries. This device is technically a kind of synchronous servo electric motor using “direct drive technology”. It provides longer battery life and high blood flow. Small volume and very low energy consumption provide a much longer battery life and a high blood flow. As the outer surface of the parts placed into the blood vessel will be completely covered with the endothelial cells and the intima layer of the arteries in time, there will be no foreign surface contacting directly with blood. As a result, no thromboembolic event or any negative effect on the cellular components of blood is expected. | 2015-07-09 |
20150190562 | Intelligent Nanomagnetic Cardiac Assist Device for a Failing Heart - The present invention is directed to a contractible and expandable jacket configured to encase at least a portion of a patient's heart. The jacket has a plurality of individual contractile cells with each of the cells having a first electrically conductive coil and a second electrically conductive coil spaced from the first coil. The first coil preferably defines at least in part a first periphery of an inner nucleus of the cell and the second coil preferably defining at least in part an outer portion of the cell spaced outwardly from the inner nucleus. When electrical current passes through the first and second coils in opposite directions, the cell contracts and when electrical current passes through the first and second coils in the same direction the cell expands. Each of the individual cells has conductive appendages for conducting information to and from the individual cells. | 2015-07-09 |
20150190563 | HYDROPHILIC RESIN COMPOUND HAVING SUGAR CHAIN AFFIXED THERETO, POLYMER SUBSTRATE FOR VIRUS-REMOVAL, AND BIOCOMPATIBLE MATERIAL - Provided is: a resin compound having an immobilized sugar chain, obtained by reacting a an epoxy-group-containing compound (B) with a hydrophilic resin (A), followed by reacting an amino-group-containing compound (C) therewith, and then reacting a sugar therewith; a virus-removal-polymer substrate obtained by coating the resin compound on a polymer support to immobilize a sugar chain that can adsorb a virus; and a biocompatible material using the resin compound. | 2015-07-09 |
20150190564 | SYSTEMS AND METHODS FOR LIMB TREATMENT - A method of delivering a medicament to a limb of a patient body includes isolating a circulatory system of the limb from a circulatory system of the patient body, wherein the limb circulatory system is substantially all limb arteries and substantially all limb veins located between an isolation region and an end of the limb. A perfusion catheter is inserted into a limb artery in an antegrade position, while a collection catheter is inserted into a limb vein in a retrograde position. The blood flow of the limb circulatory system is then circulated by collecting the blood flow with the collection catheter and delivering the blood flow with the perfusion catheter. A medicament is perfused into the limb circulatory system with the perfusion catheter. | 2015-07-09 |
20150190565 | LIQUID SUPPLY DEVICE AND BIOLOGICAL CLEANING DEVICE - The purpose of the present invention is to provide a liquid supply device and biological cleaning device that, by supplying a sterile liquid including low-flow, low-pressure microbubbles, can dramatically increase cleaning effects and clean quickly and neatly without damaging a biological tissue. A liquid supply device | 2015-07-09 |
20150190566 | PREFILLED SYRINGE OUTER CYLINDER AND PREFILLED SYRINGE OUTER CYLINDER PACKAGING - A prefilled syringe outer cylinder packaging includes a container having an upper face that has an upper face opening; an outer cylinder holding member that is located in the container and includes at least one outer cylinder holding opening part; at least one prefilled syringe outer cylinder that is held by the outer cylinder holding member; and a removable sheet-shaped lid member that seals the upper face opening of the container. The prefilled syringe outer cylinder includes: an outer cylinder main body part; a flange part; a nozzle part that is provided at a tip part of the outer cylinder main body part and has a tip opening part at its tip; and a distal cylindrical part that covers the nozzle part, has a diameter that is larger than an outer diameter of the outer cylinder main body part, and passes through the outer cylinder holding opening part. | 2015-07-09 |
20150190567 | EQUIPMENT MOUNTING APPARATUS AND METHOD OF CONTROLLING EQUIPMENT MOUNTING APPARATUS - An equipment mounting apparatus on which a plurality of equipment devices are mountable, each equipment device having, in a memory thereof, drug dosage information associated with drug usage location information, includes a main body having a plurality of installation portions, each installation portion being configured to receive one of the equipment devices. Each of the equipment devices is configured such that, when the drug usage location information is specified, the equipment device displays the related drug dosage information based on the drug usage location information that is specified. The equipment mounting apparatus is configured to set a standard specifying drug usage location information and to use the standard specifying drug usage location information to cause the drug usage location information of each of the plurality of equipment devices to coincide with the standard specifying drug usage location information. | 2015-07-09 |
20150190568 | PRESSURE MANAGEMENT FOR IMPLANTABLE DRUG-DELIVERY DEVICES - Excess gas generated by and within electrolytic drug-pump devices is managed by strategically facilitating catalytic recombination or sequestration of excess electrolysis gases in void regions where such gases are most likely to accumulate. | 2015-07-09 |
20150190569 | Drug Container and Drug Delivery Device - The invention relates to a drug container, comprising a flexible bag with a distal end connectable to a discharge nozzle, wherein the bag is compressible by a compression means, wherein the compression means is arranged as an axle attached to an opposite end of the bag and arranged to be rotated so as to spirally wind the bag about the axle. | 2015-07-09 |
20150190570 | CATHETER ASSEMBLIES WITH VALVES AND RELATED METHODS - Needle assemblies with valves and related methods are disclosed. An exemplary needle assembly includes a needle hub with a needle attached to a distal end of the needle hub and a catheter hub having a wall structure defining an interior cavity and a catheter tube extending distally therefrom having the needle projecting through the catheter tube. A valve with a cylindrical walled structure and a disc with a plurality of slits and flaps are located in the interior cavity of the catheter hub in which the cylindrical walled structure defines an open proximal end. A plurality of flexible ribs can be included and connect to an interior wall surface of the cylindrical walled structure and the disc with an actuator disposed inside the interior cavity of the catheter hub and having a distal end sized and shaped to project into the open proximal end of the valve. | 2015-07-09 |
20150190571 | Alert Device for Intravenous Drip - An alert device for use with an intravenous drip, comprises two induction ends and a control unit. The control unit comprises a circuit module, an alarm module and a power module. The two induction ends are located on a pipe of the intravenous drip and are contacting with an injection solution inside the pipe. The two induction ends are electrically connected to the control unit by wires. The circuit module detects the induction ends to determine whether the induction ends are in an open-loop status or not. The circuit module connects to the alarm module. The power module supplies power for the control unit. The induction ends uses the injection solution as a conducting means to form an electrically closed loop; when the induction ends do not contact with the injection solution, the induction ends become an open-loop, and thus the alarm module generates alarm signals. | 2015-07-09 |
20150190572 | Trace Control System for an Intravenous Drip - A trace control system for an intravenous drip includes a housing having an inlet and an outlet. A cover is mounted to a side of the housing. The cover and the housing together define a receiving space. The inlet and the outlet are provided on an outer periphery of the housing and intercommunicate with the receiving space. A shaft unit is received in the receiving space. An impeller is coupled to the shaft unit and includes at least one vane. At least two magnetic elements are provided on the at least one vane. A magnetically inductive actuator is mounted to the outer periphery of the housing and detects the at least two magnetic elements. A controller is coupled to the magnetically inductive actuator and controls operation timing of the magnetically inductive actuator. | 2015-07-09 |
20150190573 | METHOD AND APPARATUS FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP - An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. A method, system, and an article of manufacture for automatically detecting an occlusion in a medication infusion pump is provided. The electrical current to an infusion pump is measured. Based on a series of measurements of one or more variables, the infusion pump detects whether there is an occlusion in the system. | 2015-07-09 |
20150190574 | Device for Administering of Medication in Fluid Form - An infusion device for continuous infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion. The device comprises a flow regulating device comprising a passage defined by at least a first element and a second element, wherein at least one of the first and second element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases. | 2015-07-09 |
20150190575 | Injection Device With A Capacitive Proximity Sensor - An injection device for injecting medication to a patient, comprising a surface ( | 2015-07-09 |
20150190576 | METHODS AND DEVICES FOR AUTOFLUSH SYRINGES - Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration. | 2015-07-09 |
20150190577 | PORTABLE MEDICINE INJECTION DEVICE AND ANALYTE METERING SYSTEM - Methods, systems, and devices are described for setting a dose of medicine and injecting the medicine. In one aspect, a method to dispense a medicine includes inserting a cartridge containing a medicine into a cartridge holder coupled to a housing of a medicine injection device, positioning a spine component of the device to make contact with the cartridge in the cartridge holder, selecting a dose of the medicine for injection, in which the selecting includes rotating an injection component of the device to a setting corresponding to the selected dose, and linearly advancing the injection component to rotate a drive gear coupled to the injection component to drive the spine component so as to push the end of the cartridge to dispense the medicine in the amount of the selected dose. | 2015-07-09 |
20150190578 | PRODUCTION METHOD FOR PRE-FILLED SYRINGE AND PRE-FILLED SYRINGE PRODUCTION DEVICE - A production method for a pre-filled syringe includes holding a syringe assembly; reducing a pressure in the outer barrel of the syringe assembly to a set pressure; while the pressure in the outer barrel of the syringe assembly is at the set pressure, sealing the proximal end opening of the outer barrel with the gasket by disposing the gasket at a sealing position; and pushing the gasket toward the barrel tip with a sliding motion through the outer barrel to move the gasket from the sealing position to an insertion position, and the insertion position being a position at which a distal end surface of the gasket is spaced from the drug solution. After the gasket is moved to the insertion position, a pressure in a space between the drug solution and the distal end surface of the gasket is approximately equal to the atmospheric pressure. | 2015-07-09 |
20150190579 | DRUG DELIVERY DEVICE AND CARTRIDGE HOLDER FOR A DRUG DELIVERY DEVICE - A drug delivery device is provided comprising a cartridge holder comprising at least one guide track, and a body comprising at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track. The guide track comprises a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis, wherein, for connecting the cartridge holder to the body, the interaction member is configured to mechanically cooperate with the first section such that the cartridge holder is axially moved and rotated with respect to the body, and the interaction member is configured to mechanically cooperate with the second section such that the cartridge holder is rotated with respect to the body, whereby an axial movement of the cartridge holder with respect to the body is prevented. Furthermore, a cartridge holder for a drug delivery device is provided. | 2015-07-09 |
20150190580 | LIQUID ADMINISTRATION DEVICE - A liquid administration device includes an inner structure that includes a cylindrical body that has a bottom part in a distal portion thereof and an opening portion in a proximal portion thereof, a needle tube that is mounted in the distal portion of the cylindrical body and has a sharp needle tip at a distal end and a proximal end of which is communicatable with an inside of the cylindrical body, and a gasket that is located in the cylindrical body; an operation member that includes a plunger, the operation member being configured to perform a pressing operation in which the plunger is moved relative to the cylindrical body in a distal direction while being pressed; an engagement portion that includes: a first engagement portion and a second engagement portion. | 2015-07-09 |
20150190581 | PISTON FOR A CARTRIDGE AND PISTON ROD FOR A DRUG DELIVERY DEVICE - The present invention relates to a piston for a cartridge for a drug delivery device comprising: at least one annular sealing surface to radially abut against an inner side wall of a cartridge, a distal surface to confine a drug receiving volume of the cartridge, a thrust receiving surface adapted to receive a thrust exerting plunger of a drug delivery device for displacing the piston in a proximal direction relative to the side wall, wherein the thrust receiving surface comprises numerous centering elements protruding from the thrust receiving surface towards the plunger and wherein the centering elements comprise an outer shape and geometry that matches with a corresponding receptacle of the plunger, and wherein the centering elements are arranged and aligned on the circumference of an imaginary annular or circular structure. | 2015-07-09 |
20150190582 | Medicament Delivery Device - The invention relates to a medicament delivery device ( | 2015-07-09 |
20150190583 | RESETTABLE DRUG DELIVERY DEVICE - A resettable dosing mechanism comprises a dose button and a dial grip operatively coupled to the dose button. A spindle acts on a bung of a cartridge and a driver is operatively coupled between the dose button and the spindle. During an injection of the dose, the dose button moves in an axial direction to cause the spindle to administer the dose. During resetting of the dose setting mechanism, the spindle is retracted back into the dose setting mechanism. An advantageous resetting mechanism is described. | 2015-07-09 |
20150190584 | SYRINGE WITH A HOLLOW PLUNGER - A syringe for mixing and ejecting an active pharmaceutical ingredient is disclosed. The syringe is designed in such a manner that it is ensured that substantially all of the mixed drug is ejected, and in such a manner that an active pharmaceutical ingredient can be lyophilized directly into the syringe. The syringe comprises a syringe body, a first plunger arranged movably inside the syringe body and a second plunger arranged movably inside the first plunger. In one aspect the second plunger comprises a first plunger part and a second plunger part, and the first and second plunger parts are adapted to cooperate to collapse the cavity of the first plunger. In a second aspect the cavity of the first plunger has a first diameter at a distal end and a second diameter at a proximal end, the first diameter being smaller than the second diameter. | 2015-07-09 |
20150190585 | DRUG ADMINISTRATION INSTRUMENT - A drug administration instrument including a syringe including: a tubular surrounding periphery portion forming a drug chamber configured to store a drug; a discharge part disposed at a first axial end of the surrounding periphery portion; and a flange portion disposed at a second axial end of the surrounding periphery portion; and a sheath member having a tubular shape, surrounding an outer circumference of the surrounding periphery portion of the syringe, and holding the syringe. The sheath member includes a fitting part configured to support at least one of the surrounding periphery portion and the discharge part of the syringe. | 2015-07-09 |
20150190586 | INJECTOR - An injector includes a hollow needle; a main body unit including a needle holding portion that holds the needle; and a protection device configured to cover the needle before and after puncturing a puncture target with the needle. The protection device includes: an inner member attached to the needle holding portion and being freely rotatable around an outer periphery of the needle holding portion; and an outer member configured to (i) cover an outer side of the needle and the inner member before puncturing, (ii) expose the needle by moving toward a proximal end side relative to the main body unit at a time of puncturing, and (iii) cover a distal end of the needle by moving toward a distal end side relative to the main body unit after puncturing. | 2015-07-09 |
20150190587 | VASCULAR ACCESS DEVICE AND GUIDING PORTION - According to various embodiments, a method and system to obtain access to a blood vessel underneath a skin layer that may preserve lifespan of the blood vessel and reduce executional skill variability may be provided. The method includes placing a guiding portion between the blood vessel and the skin layer; and configuring the guiding portion to receive and guide a needle to reach the same location of the blood vessel repeatedly and consistently; and forming a resultant scarred track between the blood vessel and the skin layer as the guiding portion is resorbed over time. The system includes a vascular access device configurable to first possess strength to penetrate through a tissue layer, subsequently possess flexibility to conform to the surrounding tissue beneath the tissue layer; and a guiding portion which may be resorbable, wherein the inlet includes a larger diameter compared to the outlet. | 2015-07-09 |
20150190588 | INSERTION MECHANISMS HAVING VENTED FLUID PATHWAYS FOR DRUG DELIVERY PUMPS - An insertion mechanism having a vented fluid pathway includes an insertion biasing member | 2015-07-09 |
20150190589 | INJECTION DEVICE - The invention provides an injector comprising a body and a container. The body has an injection opening and including a drive mechanism which can be actuated to move the container within the body and inject medication from the container through the injection opening. The container comprises an outlet and includes an injection needle releasably coupled thereto. The injection needle comprises a hub and a needle. The hub extends along a first axis between a connecting end and a needle end. The connection end comprises connection means for connecting to the container and the needle connecting to the hub at a needle end. The needle extends from the hub along the first axis to an injection end. The injection needle comprises a channel extending from the connection end of the hub to the injection end of the needle. The hub comprises at least one reference shoulder extending radially from the hub and directed towards the injection end. The injection needle further comprises a needle shield, the needle shield releasably coupled to the needle hub and substantially covering the needle. The body further includes a body stop, the body stop comprises a shoulder extending radially inwardly from the body to define an aperture though which the needle shield, but not the reference shoulder can pass. The body stop being configured to contact the at least one reference shoulder extending from the hub to limit the distance the injection end of the needle extends out of the injection opening. | 2015-07-09 |
20150190590 | Injection Device - The invention refers to an injection device comprising a delivery mechanism for injection of a medicament, preferably through a needle, and an end of dose mechanism comprising a feedback element, wherein the end of dose mechanism is operable to be activated at a position at which the delivery mechanism reaches the end of the dose and the end of dose mechanism is further operable to force the feedback element to move into a feedback direction which is opposite or parallel to the activation direction of a release button and/or into the longitudinal direction, wherein the activation direction is preferably a longitudinal direction of the device. | 2015-07-09 |
20150190591 | DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY - An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal. | 2015-07-09 |
20150190592 | APPARATUS AND METHOD FOR AEROSOL DELIVERY TO THE LUNGS OR OTHER LOCATIONS OF THE BODY - This disclosure relates to an apparatus useful for the delivery of aerosols, such as those containing drugs, to the lungs or other locations in the body. The disclosure also relates to methods of administering an aerosol to the lungs or other locations in the body of a patient. | 2015-07-09 |
20150190593 | POWDER FILLING PROCESSES - A method for filling a plurality of microdepressions in a major surface of a web with finely divided powder in which the web is fed continuously to and through a powder filling stage including a driven roller. A method of manufacturing an elongate carrier with microdepressions containing finely divided powder comprising steps filling a plurality of microdepressions in a major surface of a web as described, removing from upper surface of the web excess powder not filled within the microdepressions and remaining on areas of the surface between the depressions, and optionally slitting and/or cutting the web in width and/or length. | 2015-07-09 |
20150190594 | DRY-POWDER INHALATION DEVICE - An improved dry-powder inhalation device having a casing having an air inlet located at a first terminus; a powder delivery port located at a second terminus, which is positioned distal to the air inlet; and an elongated support panel located within an interior of the casing and being fitted within the casing so as to partially rotate therein about a single axis. The support panel has at least one compartment containing dry-powder located proximally to the second terminus, and the casing has a plurality of needle-like structures located proximal to the delivery port and arranged above the dry-powder compartment. The compartment with a dry-powder includes a blister structure encasing the dry-powder, whereby airflow through the device causes the elongated support panel to partially rotate repeatedly within the casing, thereby striking the plurality of needle-like structures and releasing the dry-powder in the airflow. | 2015-07-09 |
20150190595 | DRY-POWDER INHALATION DEVICE - A dry-powder inhalation device including a casing having at least one push button located on an external portion thereof, the push button including at least one pin structure, an air inlet located at a first terminus of the casing; a powder delivery port located at a second terminus of the casing and is positioned distal to the air inlet; and an elongated support panel located within an interior of the casing and being fitted within the casing so as to partially rotate therein about a single axis. The support panel has at least one compartment containing dry-powder located proximal to the first terminus, and the at least one pin structure is located proximal to the air inlet and arranged above the dry-powder compartment. The compartment with a dry-powder includes a blister structure encasing the dry-powder, whereby airflow through the device causes the elongated support panel to partially rotate repeatedly within the casing, thereby striking the plurality of needle-like structures and releasing the dry-powder in the airflow. | 2015-07-09 |
20150190596 | METHODS AND APPARATUS FOR VARYING THE BACK-UP RATE FOR A VENTILATOR - A ventilator device delivers ventilatory support to a patient in a back up timed mode when patient respiration is not detected or a spontaneous mode when patient respiration is detected. The timing threshold governing the back-up mode is chosen to deviate from normal expected respiration time for the patient to promote patient initiated ventilation in the spontaneous mode but permit back-up ventilation in the event of apnea. Automated adjustments to the timing threshold during the timed mode are made from the less vigilant timing threshold to a more vigilant threshold at or near a timing of normal expected breathing of the patient. Such adjustments may be made from a minimum to a maximum vigilance timing settings or incrementally there between as a function of time in the timed mode which is preferably the number of delivered machine breaths. | 2015-07-09 |
20150190597 | ORAL CARE SYSTEM METHOD AND KIT - A system for oral care of patients ventilated with an ETT tube | 2015-07-09 |
20150190598 | Sputum Apparatus, Artificial Ventilation System, and Method for Operating Sputum Apparatus - A sputum apparatus includes a suction line, a switching unit, a measurement unit, and a control unit. The suction line has a suction inlet which aspirates sputum produced in patient's respiratory tract; and an accommodating part maintained at negative pressure, which accommodates the aspirated sputum. The switching unit is in the suction line, and can switch between first state where the suction inlet communicates with the accommodating part, and second state where the suction inlet is shutoff from the accommodating part. The measurement unit measures the expired air being aspirated into the accommodating part, under the first state. The control unit can switch the switching unit from the second state to the first state during expiration, and keep the first state when the expired air measured by the measurement unit is under predetermined value. | 2015-07-09 |
20150190599 | ENDOSCOPIC BITE BLOCK - There is provided herein, a bite block comprising an insertion channel and an airway channel, wherein the airway channel is adapted to receive exhaled breath and wherein the first insert channel is adapted to pass a medical instrument. There is provided herein, a bite block comprising an oral insert channel, wherein a portion of said channel opens into a cavity adapted to slidably receive an oral prong the oral insert channel is adapted to receive exhaled breath. | 2015-07-09 |
20150190600 | PATIENT INTERFACE - A patient interface comprises a patient interface element for delivering a gas a patient, and a forehead support. An improved adjustment mechanism is provided for the forehead support. | 2015-07-09 |
20150190601 | FOREHEAD PAD FOR RESPIRATORY MASK - A forehead pad for use in a respiratory mask with a forehead support, which includes a base portion to contact a user's forehead, a support post connected to the base portion, and a head adapted to connect the support post to a forehead support. A pair of forehead pads may be joined with a connector. | 2015-07-09 |
20150190602 | PATIENT INTERFACE SYSTEMS - A patient interface structure for delivery of respiratory therapy to a patient includes a front plate configured to conform to the shape of the patient's face; a mouth cushion defining a breathing chamber and provided to the front plate and configured to seal around the patient's mouth; and a nasal cushion configured to seal the patient's nasal airways. The nasal cushion is supported by the mouth cushion, does not contact a bridge of the patient's nose in use, and extends at least partially into the breathing chamber. A patient interface system includes a patient interface structure and a patient interface structure positioning system configured to position, stabilize and secure the patient interface structure in sealing engagement with the patient's face. | 2015-07-09 |
20150190603 | PORTABLE MANUAL VENTILATION DEVICE - A portable, compact closed circuit ventilation device for manual ventilation of a patient undergoing a surgical or medical procedure that requires sedation as well as emergency management of respiratory failure. One example embodiment includes a closed breathing circuit having a manually squeezable bag, a carbon dioxide absorption canister, a plurality of valves, a gas port and a plurality of sensors for measuring Tidal Volume (TV), Peak Airway Pressure (PAP) and End Tidal CO2 (ETCO2). Another example embodiment includes an open breathing circuit having a bag, valves and sensors. A monitor displays the sensor measurements during the respiratory phases. In a spontaneously breathing patient the device may be used to assess the adequacy of patient's respiratory efforts. During manual or assisted ventilation, the monitor assures safe and efficacious ventilation by the closed breathing circuit. | 2015-07-09 |
20150190604 | GAS GENERATING SYSTEM FOR HEALTH USE - A gas generating system for health use is provided, comprising a hydrogen-oxygen gas generator and an atomized/volatile gas generator. The hydrogen-oxygen gas generator has a first casing. The first casing accommodates an electrolysis device for electrolyzing water in order to produce a gas mixture of hydrogen and oxygen. The atomized/volatile gas generator has a second casing, the second casing accommodates a gas mixing camber coupled to the electrolysis device to receive and combine the gas mixture of hydrogen and oxygen with water vapor, an atomized medicine, a volatile essential oil or any combination thereof in order to produce a healthy gas for a user to inhale. | 2015-07-09 |
20150190605 | POSITIVE AIRWAY PRESSURE DEVICE - A positive airway pressure (PAP) device for supplying a flow of breathable gas to a patient includes a flow generator configured to pressurize a flow of breathable gas and a humidifier configured to receive and humidify the pressurized flow of breathable gas from the flow generator. The PAP device also includes a power source. The flow generator, humidifier and power source are positioned so that heat generated by at least one of the flow generator and the power source is conveyed to water in the humidifier. | 2015-07-09 |
20150190606 | VENT VALVE ASSEMBLY - A vent valve apparatus ( | 2015-07-09 |
20150190607 | CONTROL METHOD, CONTROL DEVICE, AND EYE MASK - A control method includes the steps of: (a) monitoring an electrooculogram signal of a user using an electrooculogram sensor for monitoring the electrooculogram signal of the user; (b) determining whether or not a sleep state of the user is a non-rapid eye movement (non-REM) sleep state, based on the electrooculogram signal monitored in step (a); and (c) performing a control operation to cause an element capable of warming the eye area of the user to warm an eye area of the user when the sleep state of the user is determined not to be the non-REM sleep state in step (b). | 2015-07-09 |
20150190608 | REALTIME FEEDBACK RESPONSE SYSTEM AND METHODS OF USING THE SAME - Provided herein are apparatus and methods of relaxation. In particular, disclosed herein includes a system that provides realtime or near realtime feedback response to a user in order to achieve a relaxation response. In particular, the realtime feedback response comprises aural signals relating to the user's own heartbeat, breathing, or a combination thereof | 2015-07-09 |
20150190609 | Device, Method, Medium for Guiding a User to a Desired Sleep State - A device includes a sleep depth data acquisition unit configured to acquire sleep depth data indicating a sleep depth of a user in a state in which a sound is being emitted. The device also includes a generation unit configured to generate influence data indicating an influence exerted on a variation with time of the sleep depth of the user by the sound based on a variation with time of the sleep depth indicated by the sleep depth data acquired by the sleep depth data acquisition unit and a variation with time of the sleep depth serving as a reference relating to the user. | 2015-07-09 |
20150190610 | CABLE ARRANGER - Catheterization employing a cable extending from the catheter to a fixed point of attachment is performed by providing a sensor to detect rotation of the catheter about its longitudinal axis, the rotation causing the cable to form a twist. The cable extends through a cable arranger that operates to remove the twist. A controller receives signals from the sensor and generates control signals to actuate the cable arranger responsively to the signals from the sensor. | 2015-07-09 |
20150190611 | PERICARDIAL ACCESS DEVICE AND ITS METHODS OF USE - A pericardial access device includes a first tube, a second tube coupled to the first tube, and a biasing mechanism coupled to the second tube. The pericardial access device is moveable between an expanded configuration and a contracted configuration. The biasing mechanism biases the pericardial access device towards the expanded configuration, and the pericardial access device moves towards the contracted configuration when a force is applied to the second tube. | 2015-07-09 |
20150190612 | CATHETER ASSEMBLIES HAVING A PROTECTIVE SHEATH AND METHODS OF MANUFACTURE - Catheters and methods of making catheters are provided which include a connector with a guide wire channel and an inflation channel, a shaft extending from a proximal end to a distal end and having a guide wire lumen and an inflation lumen, the shaft being connected, at its proximal end, to the connector so that said guidewire lumen and inflation lumen are mechanically and fluidly connected with said guide wire channel and inflation channel respectively. The connection is realized in correspondence to a kink portion. Such catheters may include a protective sheath placed around an external wall of the shaft extending from a first sheath end, axially placed at a first distance from the proximal end of the shaft so as to allow direct contact and fixation between the external wall of the shaft and the internal wall of the kink portion, to a second sheath end. | 2015-07-09 |
20150190613 | MANUALLY POSITIONED ARMATURE SYSTEM AND METHOD OF USE - A manually positionable armature system including a flexible semi-rigid housing including an inner wall, a connecter coupled to the housing to connect the housing to a holding structure, a holder coupled to the housing to hold an instrument in place during a procedure, a compressible media disposed within the flexible semi-rigid housing, an adjustable volume member disposed within the compressible media within the flexible semi-rigid housing, the adjustable volume member adjustable between at least a first volume state where the compressible media is less compressed against the inner wall of the housing and the flexible semi-rigid housing is freely positionable and a second volume state where the compressible media is more compacted against the inner wall of the housing, rigidizing and fixing the flexible semi-rigid housing in a desired orientation. | 2015-07-09 |
20150190614 | MR-Capable or RF-Capable Medical Guide Wire - A medical guide wire is provided having a wire core made, for example, of MR-invisible material and a sheath that surrounds the wire core at least sectionally and so as to be in touching contact therewith. The sheath can have a multilayer structure which has at least two solid material layers and/or fiber layers which are formed by different, MR-invisible plastics materials. The MR marker has at least one MR marker element which is integrated at least partially into the multilayer structure of the sheath or is surrounded thereby. | 2015-07-09 |
20150190615 | CATHETER SYSTEM - A catheter system includes an elongate catheter having a lumen extending at least partially therethrough, and a leading catheter end segment, a guidewire positionable within the lumen of the catheter, and fastening structure supported adjacent the leading catheter end segment. The guidewire and the catheter are adapted for relative movement. The fastening structure is dimensioned to selectively engage the guidewire to secure the guidewire with respect to the leading catheter end segment such that movement of the guidewire causes deflection of the leading end segment with respect to the longitudinal axis. | 2015-07-09 |
20150190616 | MEDICAL DEVICE INCLUDING MANIPULABLE PORTION WITH CONNECTED ELONGATE MEMBERS - A medical system may include a shaft member and a structure physically coupled to the shaft member. A portion of the shaft member may be sized to be delivered through a bodily opening leading to a bodily cavity. The structure may include at least two flexible couplings, each flexible coupling extending transversely from an intermediate portion of a respective one of at least two elongate members of the structure. The flexible coupling extending transversely from the intermediate portion of a first one of the at least two elongate members forms at least a part of a first closed loop arranged to receive a portion of the flexible coupling of a second one of the at least two elongate members therethrough to limit a spacing between the intermediate portions of the first and the second ones of the at least two elongate members. | 2015-07-09 |
20150190617 | GUIDE EXTENSION CATHETER - Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include a push member having a proximal portion with a proximal stiffness, a distal portion with a distal stiffness different from the proximal stiffness, and a transition portion disposed between the proximal portion and the distal portion. The transition portion may provide a smooth transition between the proximal stiffness and the distal stiffness. The push member may have a first outer diameter. A distal tubular member may be attached to the push member. The distal tubular member may have a second outer diameter larger than the first outer diameter. | 2015-07-09 |
20150190618 | Balloon Catheter With Elastomeric Sheath and Methods - Balloon catheters that include a balloon and an elastomeric sheath, each having a surface with a therapeutic agent disposed thereon, along with methods of making and methods of using the disclosed balloon catheters. | 2015-07-09 |
20150190619 | APPARATUS AND METHOD FOR DELIVERING INTRALUMINAL THERAPY - A catheter and methods for luminal therapy are provided wherein a catheter has an outer balloon with a multiplicity of apertures for infusing one or more therapeutic agents into a vessel wall, an intermediate balloon having a multiplicity of apertures offset from the apertures of outer balloon to serve as a baffle that reduces jetting and promotes uniform distribution of therapeutic agent exiting through the outer balloon, and an impermeable inner balloon disposed within the intermediate balloon that enables the intermediate and outer balloons to be forced into engagement with the vessel wall to dilate the vessel and disrupt plaque lining the vessel wall and to also facilitate the uniform delivery of the therapeutic agent. The outer balloon may include protrusions that contact the vessel wall to disrupt the plaque, bumpers to reduce washout during infusion of therapeutic agents; the intermediate balloon may include a texture, ribs or protrusions on its outer surface to prevent adhesion to the outer balloon during dilation of the vessel; and the catheter may include a guide wire lumen sized to accept an energy delivery device to delivery energy that enhances uptake of the therapeutic agent or prolongs therapeutic effectiveness of the is agent. | 2015-07-09 |
20150190620 | IMPLANTABLE SYSTEM FOR COLLECTION AND SUPPLY OF INTERSTITIAL FLUID - A system for redistributing interstitial fluid within a mammal is disclosed. The system comprises an implantable accumulation chamber, a confined flow passageway such as a catheter in communication with the accumulation chamber, and a liquid transfer pump for dispensing accumulated interstitial fluid from the accumulation chamber to a predetermined body site via the confined flow passageway. | 2015-07-09 |
20150190621 | Device and Method for Tissue Displacement in Brachytherapy - The present invention provides a device for displacing healthy or normal tissue away from radiation exposure during brachytherapy. In one embodiment, the device of the present invention comprises an inflatable component attached to the ring of a tandem and ring brachytherapy applicator. When the tandem and ring applicator is inserted, the balloon is deflated so that patient discomfort is minimized. Once the ring is in the correct position, the balloon is inflated and the rectum is displaced. The balloon remains inflated during any image guidance that is performed and for the duration of the brachytherapy treatment. The balloon is deflated prior to the removal of the ring from the body. | 2015-07-09 |
20150190622 | MEDICAL HUB AND METHOD OF USING SAME - Methods and apparatus are disclosed for making and using adjustable epidermal tissue ingrowth cuff and catheter assemblies for transcutaneous placement to provide periodic or continuous external access for medical purposes to an interior body region of a patent who requires such medical treatment over an extended period of time. | 2015-07-09 |
20150190623 | CONNECTOR - A connector includes in a main body, first to third ports each having a flow channel allowing inflow or outflow of an infusion solution, an internal flow channel configured to communicate between flow channels of the first port and the second port, and a through hole connected to an internal flow channel. In the internal flow channel, an upstream side wall surface is provided which guides infusion solution flowing into the internal flow channel from the first port to the through hole, and reduces the cross-sectional area of the flow channel for the infusion solution near the through hole relative to the cross-sectional area of the flow channel of the first port in order to increase a flow rate of the infusion solution. | 2015-07-09 |
20150190624 | POLYVINYL CHLORIDE-FREE MEDICAL TUBE, AND MOLDED ARTICLES AND MEDICAL SUPPLIES PRODUCED THEREWITH - Provided is a medical tube including at least one layer made of a composition containing a cross-copolymerized olefin-aromatic vinyl compound-diene copolymer. The medical tube according to the present invention, which has excellent kink resistance, toughness, transparency, non-adsorption of drugs, and the like, and is made of a non-toxic polyvinyl chloride (PVC)-free material, may be combined with an injection-molded article of the resin, the resultant article may be effectively used for medical supplies such as an infusion set, a blood transfusion set, a medical liquid container set, a medical catheter, and the like. | 2015-07-09 |
20150190625 | Fluid Transfer Devices - A fluid transfer device may include a fluid transfer tip that has a tapered friction fitting for a corresponding hub and an additional means for gripping a hub in a locked position when connected to the fluid transfer tip by the friction fitting. A disconnecting member is provided with a resilient bias that causes it to engage the gripping means and thereby assist in holding the hub in the locked position. The disconnecting member is moveable relative to the fluid transfer tip and against the resilient bias so as to release engagement of the gripping means, move the hub out of the locked position provided by the gripping means and release the hub from the friction fitting. | 2015-07-09 |